https://longevityharbor.com/en/entry/research/nmn-2021 https://longevityharbor.com/de/entry/research/nmn-2021 https://longevityharbor.com/en/entry/research/calerie-2023 https://longevityharbor.com/de/entry/research/calerie-2023 https://longevityharbor.com/en/entry/research/rapa-2009 https://longevityharbor.com/de/entry/research/rapa-2009 https://longevityharbor.com/en/entry/research/seno-2019 https://longevityharbor.com/de/entry/research/seno-2019 https://longevityharbor.com/en/entry/research/hallmarks-2023 https://longevityharbor.com/de/entry/research/hallmarks-2023 https://longevityharbor.com/en/entry/products/nmn https://longevityharbor.com/de/entry/products/nmn https://longevityharbor.com/en/entry/products/omega https://longevityharbor.com/de/entry/products/omega https://longevityharbor.com/en/entry/products/vitamind https://longevityharbor.com/de/entry/products/vitamind https://longevityharbor.com/en/entry/products/oura https://longevityharbor.com/de/entry/products/oura https://longevityharbor.com/en/entry/products/whoop https://longevityharbor.com/de/entry/products/whoop https://longevityharbor.com/en/entry/clinics/clp https://longevityharbor.com/de/entry/clinics/clp https://longevityharbor.com/en/entry/clinics/lanserhof https://longevityharbor.com/de/entry/clinics/lanserhof https://longevityharbor.com/en/entry/clinics/fountain https://longevityharbor.com/de/entry/clinics/fountain https://longevityharbor.com/en/entry/creators/attia https://longevityharbor.com/de/entry/creators/attia https://longevityharbor.com/en/entry/creators/patrick https://longevityharbor.com/de/entry/creators/patrick https://longevityharbor.com/en/entry/creators/nia-video https://longevityharbor.com/de/entry/creators/nia-video https://longevityharbor.com/en/entry/regulations/us https://longevityharbor.com/de/entry/regulations/us https://longevityharbor.com/en/entry/regulations/eu https://longevityharbor.com/de/entry/regulations/eu https://longevityharbor.com/en/entry/regulations/uk https://longevityharbor.com/de/entry/regulations/uk https://longevityharbor.com/en/entry/regulations/us-care https://longevityharbor.com/de/entry/regulations/us-care https://longevityharbor.com/en/watch/-1967nPCBNo Video description: light, circadian rhythm and longevity claims https://i.ytimg.com/vi/-1967nPCBNo/hqdefault.jpg The description presents sunlight as a possible key to longevity and says circadian biology may influence sleep, cognition, energy, metabolism, the heart, hormones and recovery. It names no studies, numbers or outcomes; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/-1967nPCBNo 605 2026-05-18T04:09:42.000Z 2026-10-23T00:45:05.111Z https://longevityharbor.com/de/watch/-1967nPCBNo Videobeschreibung: Licht, circadianer Rhythmus und Langlebigkeitsaussagen https://i.ytimg.com/vi/-1967nPCBNo/hqdefault.jpg Die Beschreibung stellt Sonnenlicht als möglichen Schlüssel zur Langlebigkeit dar und sagt, circadiane Biologie könne Schlaf, Kognition, Energie, Stoffwechsel, Herz, Hormone und Erholung beeinflussen. Sie nennt keine Studien, Zahlen oder Ergebnisse; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/-1967nPCBNo 605 2026-05-18T04:09:42.000Z 2026-10-23T00:45:05.111Z https://longevityharbor.com/en/watch/-2Hr-RkjLAM Legs After 60: Sitting-Rising, Walking Speed and Muscle Clues in a Video Description https://i.ytimg.com/vi/-2Hr-RkjLAM/hqdefault.jpg The description of this Feynman Explains 2.0 video says it covers sitting-rising ability, walking speed after 60, calf muscle pumping, strength versus power, muscle and blood sugar, a three-week bed rest experiment and whether fitness can improve with age. It stresses that some changes linked to aging may reflect deconditioning. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/-2Hr-RkjLAM 796 2026-10-10T12:23:47.000Z 2026-10-22T20:41:59.662Z https://longevityharbor.com/de/watch/-2Hr-RkjLAM Beine ab 60: Aufstehen vom Boden, Gehtempo und Muskelhinweise in einer Videobeschreibung https://i.ytimg.com/vi/-2Hr-RkjLAM/hqdefault.jpg Die Beschreibung dieses Videos von Feynman Explains 2.0 nennt das Aufstehen vom Boden, Gehtempo ab 60, das Pumpen der Wadenmuskeln, Kraft versus Schnellkraft, Muskeln und Blutzucker, ein dreiwöchiges Bettruhe-Experiment und die Frage, ob Fitness mit dem Alter besser werden kann. Betont wird, dass manche mit Altern verbundene Veränderungen auch Dekonditionierung widerspiegeln können. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/-2Hr-RkjLAM 796 2026-10-10T12:23:47.000Z 2026-10-22T20:41:59.662Z https://longevityharbor.com/en/watch/-5Yehv8vf7A Video description claims a 6.4–7.8 hour sleep window and slower biological aging https://i.ytimg.com/vi/-5Yehv8vf7A/hqdefault.jpg The description says Columbia University researchers studied 23 biological aging clocks across 17 organs in 500,000 UK Biobank participants and found that sleeping 6.4–7.8 hours minimizes cellular aging. This is a creator claim from the description only. https://www.youtube-nocookie.com/embed/-5Yehv8vf7A 97 2026-09-14T04:00:38.000Z 2026-10-22T22:12:54.799Z https://longevityharbor.com/de/watch/-5Yehv8vf7A Videobeschreibung behauptet ein Schlaffenster von 6,4–7,8 Stunden und langsameres biologisches Alter https://i.ytimg.com/vi/-5Yehv8vf7A/hqdefault.jpg Die Beschreibung nennt Forschende der Columbia University, die 23 biologische Altersuhren in 17 Organen bei 500.000 Teilnehmenden der UK Biobank untersucht und gefunden hätten, dass Schlaf von 6,4–7,8 Stunden zelluläres Altern minimiert. Dies ist eine Aussage des Erstellers aus der Beschreibung. https://www.youtube-nocookie.com/embed/-5Yehv8vf7A 97 2026-09-14T04:00:38.000Z 2026-10-22T22:12:54.799Z https://longevityharbor.com/en/watch/-7nd-0xU8DE Video description: anti-aging supplements and the gap to human evidence https://i.ytimg.com/vi/-7nd-0xU8DE/hqdefault.jpg The description says Dr. Zadeh separates promising longevity science from strong human evidence and notes that many widely discussed compounds still lack long-term human outcome data. https://www.youtube-nocookie.com/embed/-7nd-0xU8DE 110 2026-06-01T20:05:13.000Z 2026-10-23T00:12:26.890Z https://longevityharbor.com/de/watch/-7nd-0xU8DE Videobeschreibung: Anti-Aging-Supplemente und die Lücke zur Human-Evidenz https://i.ytimg.com/vi/-7nd-0xU8DE/hqdefault.jpg Laut Beschreibung trennt Dr. Zadeh vielversprechende Longevity-Wissenschaft von starker Human-Evidenz und betont, dass vielen diskutierten Verbindungen weiterhin Langzeitdaten zu menschlichen Endpunkten fehlen. https://www.youtube-nocookie.com/embed/-7nd-0xU8DE 110 2026-06-01T20:05:13.000Z 2026-10-23T00:12:26.890Z https://longevityharbor.com/en/watch/-BtP3z_wqHo RAPAMYCIN: How Easter Island Led To The Discovery of the mTOR Pathway [2021] https://i.ytimg.com/vi/-BtP3z_wqHo/hqdefault.jpg 👉 More longevity bioacks. Join my free community: https://www.skool.com/the-longevity-alliance/about Reading medical studies and boning up on longevity makes for some dry reading. Not so with the discovery story of rapamycin and the mTOR pathway. Today's video is a 2-parter. The first part is the history of rapamycin and it's a tale with exotic locales and not one resurrection, but two; one from the last place you'd think. The second part of this video takes a good look at several studies of rapamycin, both past and present. And we'll examine rapamycin's role in the age-related decline in immunity and loss of muscle mass. I'll admit it. I've never been a big fan of taking rapamycin to inhibit the mTOR pathway and possibly extend lifespans. But these studies have reset my thinking, and I may be changing my mind. Chapters & Timestamps: 00:00 Intro 00:50 The Story of Rapamycin 05:30 Rapamycin Studies 10:21 Rapamycin & Immunosuppression 11:55 Rapamycin & Sarcopenia 14:52 Conclusions Links to studies referred to in this video: Rapamycin extends lifespans in mice: https://www.nature.com/articles/nature08221 Opinion article on Rapamycin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814615/ Rapamycin and the quest to slow aging through drug discovery: https://pubmed.ncbi.nlm.nih.gov/32467649/ Rapalogs and COVID-19: https://pubmed.ncbi.nlm.nih.gov/33665645/ Rapamycin, sarcopenia and aging muscle: https://pubmed.ncbi.nlm.nih.gov/31454792/ ************************************************************** SOCIAL MEDIA LINKS: Facebook: https://www.facebook.com/lancehitchings/ Instagram: https://www.instagram.com/lancehitchings/ Twitter: https://twitter.com/LanceHitchings ************************************************************** AFFILIATE LINKS: Discount code for DoNotAge: LANCE Product Links for DoNotAge: Annual Subscription: https://donotage.org/subscribe/ Products : https://donotage.org/products/ Discount code for Alive By Science: LANCE10 Product Links: https://alivebyscience.com/all-pro https://www.youtube-nocookie.com/embed/-BtP3z_wqHo 1003 2021-06-08T11:00:00.000Z 2026-10-22T17:43:41.082Z https://longevityharbor.com/de/watch/-BtP3z_wqHo RAPAMYCIN: How Easter Island Led To The Discovery of the mTOR Pathway [2021] https://i.ytimg.com/vi/-BtP3z_wqHo/hqdefault.jpg 👉 More longevity bioacks. Join my free community: https://www.skool.com/the-longevity-alliance/about Reading medical studies and boning up on longevity makes for some dry reading. Not so with the discovery story of rapamycin and the mTOR pathway. Today's video is a 2-parter. The first part is the history of rapamycin and it's a tale with exotic locales and not one resurrection, but two; one from the last place you'd think. The second part of this video takes a good look at several studies of rapamycin, both past and present. And we'll examine rapamycin's role in the age-related decline in immunity and loss of muscle mass. I'll admit it. I've never been a big fan of taking rapamycin to inhibit the mTOR pathway and possibly extend lifespans. But these studies have reset my thinking, and I may be changing my mind. Chapters & Timestamps: 00:00 Intro 00:50 The Story of Rapamycin 05:30 Rapamycin Studies 10:21 Rapamycin & Immunosuppression 11:55 Rapamycin & Sarcopenia 14:52 Conclusions Links to studies referred to in this video: Rapamycin extends lifespans in mice: https://www.nature.com/articles/nature08221 Opinion article on Rapamycin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814615/ Rapamycin and the quest to slow aging through drug discovery: https://pubmed.ncbi.nlm.nih.gov/32467649/ Rapalogs and COVID-19: https://pubmed.ncbi.nlm.nih.gov/33665645/ Rapamycin, sarcopenia and aging muscle: https://pubmed.ncbi.nlm.nih.gov/31454792/ ************************************************************** SOCIAL MEDIA LINKS: Facebook: https://www.facebook.com/lancehitchings/ Instagram: https://www.instagram.com/lancehitchings/ Twitter: https://twitter.com/LanceHitchings ************************************************************** AFFILIATE LINKS: Discount code for DoNotAge: LANCE Product Links for DoNotAge: Annual Subscription: https://donotage.org/subscribe/ Products : https://donotage.org/products/ Discount code for Alive By Science: LANCE10 Product Links: https://alivebyscience.com/all-pro https://www.youtube-nocookie.com/embed/-BtP3z_wqHo 1003 2021-06-08T11:00:00.000Z 2026-10-22T17:43:41.082Z https://longevityharbor.com/en/watch/-CLu7rQBZ6M DNA Damage, Senescence & Apoptosis | 48 - Aditi Gurkar https://i.ytimg.com/vi/-CLu7rQBZ6M/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Check out the Gurkar lab: http://agresearchlab.com/ In May 2024, Matt delivered a talk at the 2024 Glenn AFAR Grantee Conference in Santa Barbara, California and met with several people doing interesting work in the longevity field. One of these was Aditi Gurkar, an assistant professor in the University of Pittsburgh's Aging Institute, Division of Geriatric Medicine whose lab focuses on the downstream effects of DNA damage on aging. Prior to setting up her lab at the University of Pittsburgh, Aditi conducted research on the impact of DNA damage on aging at Scripps Research. She also completed postdoctoral training at Massachusetts General Hospital/Harvard Medical School and the Broad Institute of MIT and Harvard, where she focused on the tumor suppressor p53 as well as on autophagy regulation. Aditi received a PhD and a B.S. from the Boston University School of Medicine and Florida International University in Miami respectively. Matt and Aditi spend much of this episode chatting about senescent cells: how Aditi developed a focus on cellular senescence and found its relevance to aging, potential therapeutic benefits of senescent cell clearance, and the much-debated question of how to define a senescent cell. They also discuss the importance of "zooming out" from narrow areas of focus in the geroscience field to find new solutions and of breaking your own models on your way to productive new directions in science. 0:00 Introduction 1:11 How Aditi became interested in the biology of aging 8:04 Some people say that the potential impact of reprogramming is small because the DNA damage is permanent: Aditi's take 11:52 How do you differentiate between cellular senescence and apoptosis? 13:08 Cellular senescence and lipid mediators that may drive inflammation 16:06 Aditi's early work in cellular senescence + why senescence happens 19:03 How can we define a senescent cell? 22:15 Reprogramming senescent cells 24:20 The different flavors of senescent cells 26: https://www.youtube-nocookie.com/embed/-CLu7rQBZ6M 3950 2024-07-12T14:00:00.000Z 2026-10-22T19:04:38.823Z https://longevityharbor.com/de/watch/-CLu7rQBZ6M DNA Damage, Senescence & Apoptosis | 48 - Aditi Gurkar https://i.ytimg.com/vi/-CLu7rQBZ6M/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Check out the Gurkar lab: http://agresearchlab.com/ In May 2024, Matt delivered a talk at the 2024 Glenn AFAR Grantee Conference in Santa Barbara, California and met with several people doing interesting work in the longevity field. One of these was Aditi Gurkar, an assistant professor in the University of Pittsburgh's Aging Institute, Division of Geriatric Medicine whose lab focuses on the downstream effects of DNA damage on aging. Prior to setting up her lab at the University of Pittsburgh, Aditi conducted research on the impact of DNA damage on aging at Scripps Research. She also completed postdoctoral training at Massachusetts General Hospital/Harvard Medical School and the Broad Institute of MIT and Harvard, where she focused on the tumor suppressor p53 as well as on autophagy regulation. Aditi received a PhD and a B.S. from the Boston University School of Medicine and Florida International University in Miami respectively. Matt and Aditi spend much of this episode chatting about senescent cells: how Aditi developed a focus on cellular senescence and found its relevance to aging, potential therapeutic benefits of senescent cell clearance, and the much-debated question of how to define a senescent cell. They also discuss the importance of "zooming out" from narrow areas of focus in the geroscience field to find new solutions and of breaking your own models on your way to productive new directions in science. 0:00 Introduction 1:11 How Aditi became interested in the biology of aging 8:04 Some people say that the potential impact of reprogramming is small because the DNA damage is permanent: Aditi's take 11:52 How do you differentiate between cellular senescence and apoptosis? 13:08 Cellular senescence and lipid mediators that may drive inflammation 16:06 Aditi's early work in cellular senescence + why senescence happens 19:03 How can we define a senescent cell? 22:15 Reprogramming senescent cells 24:20 The different flavors of senescent cells 26: https://www.youtube-nocookie.com/embed/-CLu7rQBZ6M 3950 2024-07-12T14:00:00.000Z 2026-10-22T19:04:38.823Z https://longevityharbor.com/en/watch/-Co6qYFqvFY Video description: zombie cells and why ageing feels faster after 75 https://i.ytimg.com/vi/-Co6qYFqvFY/hqdefault.jpg The description says the video explains cellular senescence ('zombie cells'), why the immune system may stop removing them, inflammaging, and factors said to slow this process. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/-Co6qYFqvFY 1886 2026-09-26T13:00:34.000Z 2026-10-22T21:48:20.132Z https://longevityharbor.com/de/watch/-Co6qYFqvFY Videobeschreibung: Zombie-Zellen und schnelleres Altern nach 75 https://i.ytimg.com/vi/-Co6qYFqvFY/hqdefault.jpg Laut Beschreibung erklärt das Video zelluläre Seneszenz („Zombie-Zellen“), warum das Immunsystem sie womöglich nicht mehr entfernt, Inflammaging und Faktoren, die diesen Prozess angeblich verlangsamen. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/-Co6qYFqvFY 1886 2026-09-26T13:00:34.000Z 2026-10-22T21:48:20.132Z https://longevityharbor.com/en/watch/-DkgwYsHfHo EpiAge: NGS-Based ELOVL2 Epigenetic Clock for Aging Assessment | Aging-US https://i.ytimg.com/vi/-DkgwYsHfHo/hqdefault.jpg Aging-US #published this #research paper on January 22, 2025, in Volume 17, Issue 1, entitled “EpiAge: a next-generation sequencing-based ELOVL2 epigenetic clock for biological age assessment in saliva and blood across health and disease" by researchers from EpiMedTech Global, Singapore 409051, Singapore; HKG Epitherapeutics Ltd., Hong Kong SAR, China; Gerald Bronfman Department of Oncology, McGill University, Montreal H4A 3T2, Canada; Department of Pharmacology & Therapeutics, McGill University, Montreal H3G 1Y6, Canada; Visiting Professor, Department of Pharmacology, Oxford University, Oxford OX13QT, UK; Department of Drug and Health Sciences, University of Catania, Catania 95125, Italy; Neuropharmacology and Translational Neurosciences Research Unit, Oasi Research Institute-IRCCS, Troina 94018, Italy. @EpiMedTechGlobal #aging #epigeneticclocks #alzheimers #biologicalage #health #spotlight #openaccess #openscience #peerreviewed #journalpublication #publishing #meded DOI - https://doi.org/10.18632/aging.206188 Corresponding author - Moshe Szyf - moshe.szyf@epimedtech.com Author interview - https://www.youtube.com/watch?v=NA8Vctks0gY Abstract This study introduces EpiAgePublic, a new method to estimate biological age using only three specific sites on the gene ELOVL2, known for its connection to aging. Unlike traditional methods that require complex and extensive data, our model uses a simpler approach that is well-suited for next-generation sequencing technology, which is a more advanced method of analyzing DNA methylation. This new model overcomes some of the common challenges found in older methods, such as errors due to sample quality and processing variations. We tested EpiAgePublic with a large and varied group of over 4,600 people to ensure its accuracy. It performed on par with, and sometimes better than, more complicated models that use much more data for age estimation. We examined its effectiveness in understanding how factors like HIV infection and stress affect aging, confirming its usefulness https://www.youtube-nocookie.com/embed/-DkgwYsHfHo 114 2025-02-20T18:43:01.000Z 2026-10-22T19:43:51.839Z https://longevityharbor.com/de/watch/-DkgwYsHfHo EpiAge: NGS-Based ELOVL2 Epigenetic Clock for Aging Assessment | Aging-US https://i.ytimg.com/vi/-DkgwYsHfHo/hqdefault.jpg Aging-US #published this #research paper on January 22, 2025, in Volume 17, Issue 1, entitled “EpiAge: a next-generation sequencing-based ELOVL2 epigenetic clock for biological age assessment in saliva and blood across health and disease" by researchers from EpiMedTech Global, Singapore 409051, Singapore; HKG Epitherapeutics Ltd., Hong Kong SAR, China; Gerald Bronfman Department of Oncology, McGill University, Montreal H4A 3T2, Canada; Department of Pharmacology & Therapeutics, McGill University, Montreal H3G 1Y6, Canada; Visiting Professor, Department of Pharmacology, Oxford University, Oxford OX13QT, UK; Department of Drug and Health Sciences, University of Catania, Catania 95125, Italy; Neuropharmacology and Translational Neurosciences Research Unit, Oasi Research Institute-IRCCS, Troina 94018, Italy. @EpiMedTechGlobal #aging #epigeneticclocks #alzheimers #biologicalage #health #spotlight #openaccess #openscience #peerreviewed #journalpublication #publishing #meded DOI - https://doi.org/10.18632/aging.206188 Corresponding author - Moshe Szyf - moshe.szyf@epimedtech.com Author interview - https://www.youtube.com/watch?v=NA8Vctks0gY Abstract This study introduces EpiAgePublic, a new method to estimate biological age using only three specific sites on the gene ELOVL2, known for its connection to aging. Unlike traditional methods that require complex and extensive data, our model uses a simpler approach that is well-suited for next-generation sequencing technology, which is a more advanced method of analyzing DNA methylation. This new model overcomes some of the common challenges found in older methods, such as errors due to sample quality and processing variations. We tested EpiAgePublic with a large and varied group of over 4,600 people to ensure its accuracy. It performed on par with, and sometimes better than, more complicated models that use much more data for age estimation. We examined its effectiveness in understanding how factors like HIV infection and stress affect aging, confirming its usefulness https://www.youtube-nocookie.com/embed/-DkgwYsHfHo 114 2025-02-20T18:43:01.000Z 2026-10-22T19:43:51.839Z https://longevityharbor.com/en/watch/-H6cDIl6pgo “Zombie” Senescent cells may play HUGE role in LIVING LONGER, Here's How: | 22 - Natalia Mitin https://i.ytimg.com/vi/-H6cDIl6pgo/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Senescent cells, cells that cease to divide and proliferate while remaining metabolically active, are a complex and intriguing aspect of biological aging. They serve as both a protective mechanism against cancer, preventing damaged cells from uncontrollable replication, as well as a contributor to tissue dysfunction and age-related pathologies such as cardiovascular disease, neurodegenerative disorders, and diabetes. The precise mechanisms that underlie senescence and its contributions to the aging process remain areas of ongoing investigation and debate. In this episode, Matt chats with Sapere Bio co-founder and CEO Natalia Mitin about measuring cellular senescence, using those measurements in the clinic, and the complex and heterogeneous role of cellular senescence in aging and disease. They also discuss Natalia's personal experiences using rapamycin off-label to improve energy levels and immune function, the importance of monitoring biomarkers when using off-label medications, and Natalia's thoughts on "rapamycin for all". Prior to co-founding Sapere Bio, Natalia served as an assistant professor at the University of North Carolina at Chapel Hill's Department of Pharmacology. She spent over two decades developing assays for use in cancer research. She holds a B.S. in chemical engineering from the Mendeleev Institute for Chemical Technology and a PhD in biochemistry and molecular biology from Bowling Green State University. Optispan uses the SapereX test in its healthspan optimization program. 0:00 Trailer 0:46 Introduction 1:22 How Natalia's background led her to start Sapere Bio 11:46 What does the SapereX test actually measure? 22:11 Is the marker of autophagy inhibition in the SapereX test responsive to rapamycin? 24:58 The clinical utility of the SapereX test 31:37 Are clinical trials using tools like SapereX to measure cellular senescence? 33:00 When is too little senescence detrimental? 42:30 Can we design a test for measuring how well our b https://www.youtube-nocookie.com/embed/-H6cDIl6pgo 3567 2024-04-11T14:00:00.000Z 2026-10-22T19:04:38.727Z https://longevityharbor.com/de/watch/-H6cDIl6pgo “Zombie” Senescent cells may play HUGE role in LIVING LONGER, Here's How: | 22 - Natalia Mitin https://i.ytimg.com/vi/-H6cDIl6pgo/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Senescent cells, cells that cease to divide and proliferate while remaining metabolically active, are a complex and intriguing aspect of biological aging. They serve as both a protective mechanism against cancer, preventing damaged cells from uncontrollable replication, as well as a contributor to tissue dysfunction and age-related pathologies such as cardiovascular disease, neurodegenerative disorders, and diabetes. The precise mechanisms that underlie senescence and its contributions to the aging process remain areas of ongoing investigation and debate. In this episode, Matt chats with Sapere Bio co-founder and CEO Natalia Mitin about measuring cellular senescence, using those measurements in the clinic, and the complex and heterogeneous role of cellular senescence in aging and disease. They also discuss Natalia's personal experiences using rapamycin off-label to improve energy levels and immune function, the importance of monitoring biomarkers when using off-label medications, and Natalia's thoughts on "rapamycin for all". Prior to co-founding Sapere Bio, Natalia served as an assistant professor at the University of North Carolina at Chapel Hill's Department of Pharmacology. She spent over two decades developing assays for use in cancer research. She holds a B.S. in chemical engineering from the Mendeleev Institute for Chemical Technology and a PhD in biochemistry and molecular biology from Bowling Green State University. Optispan uses the SapereX test in its healthspan optimization program. 0:00 Trailer 0:46 Introduction 1:22 How Natalia's background led her to start Sapere Bio 11:46 What does the SapereX test actually measure? 22:11 Is the marker of autophagy inhibition in the SapereX test responsive to rapamycin? 24:58 The clinical utility of the SapereX test 31:37 Are clinical trials using tools like SapereX to measure cellular senescence? 33:00 When is too little senescence detrimental? 42:30 Can we design a test for measuring how well our b https://www.youtube-nocookie.com/embed/-H6cDIl6pgo 3567 2024-04-11T14:00:00.000Z 2026-10-22T19:04:38.727Z https://longevityharbor.com/en/watch/-JMAspl8OGw #09 – David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR https://i.ytimg.com/vi/-JMAspl8OGw/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Original release date: 8/13/2018 In this episode, my good friend David Sabatini delves into his extensive work with the mechanistic target of rapamycin—better known as mTOR—and rapamycin. The compound rapamycin is the only known pharmacological agent to extend lifespan all the way from yeast to mammals—across a billion years of evolution. David, a professor of biology and a member of the Whitehead Institute at MIT, shares his remarkable journey and discovery of mTOR in mammalian cells and its central role in nutrient sensing and longevity. Fasting, rapamycin, mTOR, autophagy, gedankenexperiments: having this conversation with David is like being the proverbial kid in the world’s greatest candy store. We discuss: -mTOR and David’s student years [4:30]; -Rapamycin and the discovery of mTOR [8:15]; -The connection between rapamycin, mTOR, and longevity [30:30]; -mTOR as the cell’s general contractor [34:45]; -The effect of glucose, insulin, and amino acids on mTORC1 [42:50]; -Methionine sensing and restriction [49:45]; -An intermittent approach to rapamycin [54:30]; -Rapamycin’s effects on cancer, cardiovascular disease, and neurodegeneration [57:00]; -Gedankenexperiment: couch potatoes on rapamycin vs perfectly behaved humans [1:03:15]; -David’s dream experiment with no resource constraints [1:07:00]; and -More. Show notes page: https://peterattiamd.com/davidsabatini/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 10 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. The practice applies nutritional biochemistry, exercise physiology, sleep physiology, techniques to increase distress tolerance, lipi https://www.youtube-nocookie.com/embed/-JMAspl8OGw 4288 2019-12-23T03:03:12.000Z 2026-10-22T17:43:41.074Z https://longevityharbor.com/de/watch/-JMAspl8OGw #09 – David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR https://i.ytimg.com/vi/-JMAspl8OGw/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Original release date: 8/13/2018 In this episode, my good friend David Sabatini delves into his extensive work with the mechanistic target of rapamycin—better known as mTOR—and rapamycin. The compound rapamycin is the only known pharmacological agent to extend lifespan all the way from yeast to mammals—across a billion years of evolution. David, a professor of biology and a member of the Whitehead Institute at MIT, shares his remarkable journey and discovery of mTOR in mammalian cells and its central role in nutrient sensing and longevity. Fasting, rapamycin, mTOR, autophagy, gedankenexperiments: having this conversation with David is like being the proverbial kid in the world’s greatest candy store. We discuss: -mTOR and David’s student years [4:30]; -Rapamycin and the discovery of mTOR [8:15]; -The connection between rapamycin, mTOR, and longevity [30:30]; -mTOR as the cell’s general contractor [34:45]; -The effect of glucose, insulin, and amino acids on mTORC1 [42:50]; -Methionine sensing and restriction [49:45]; -An intermittent approach to rapamycin [54:30]; -Rapamycin’s effects on cancer, cardiovascular disease, and neurodegeneration [57:00]; -Gedankenexperiment: couch potatoes on rapamycin vs perfectly behaved humans [1:03:15]; -David’s dream experiment with no resource constraints [1:07:00]; and -More. Show notes page: https://peterattiamd.com/davidsabatini/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 10 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. The practice applies nutritional biochemistry, exercise physiology, sleep physiology, techniques to increase distress tolerance, lipi https://www.youtube-nocookie.com/embed/-JMAspl8OGw 4288 2019-12-23T03:03:12.000Z 2026-10-22T17:43:41.074Z https://longevityharbor.com/en/watch/-Q_eSV70hsc Video description on senescence, senolytics and partial reprogramming https://i.ytimg.com/vi/-Q_eSV70hsc/hqdefault.jpg The description says the video covers cellular senescence, senolytic drugs such as dasatinib plus quercetin, partial reprogramming with Yamanaka factors, a 2020 Sinclair Lab mouse vision experiment, NAD+ and sirtuins, and challenges such as cancer risk. https://www.youtube-nocookie.com/embed/-Q_eSV70hsc 240 2026-01-11T14:30:00.000Z 2026-10-23T02:56:12.804Z https://longevityharbor.com/de/watch/-Q_eSV70hsc Videobeschreibung zu Seneszenz, Senolytika und Teil-Reprogrammierung https://i.ytimg.com/vi/-Q_eSV70hsc/hqdefault.jpg Laut Beschreibung behandelt das Video zelluläre Seneszenz, Senolytika wie Dasatinib plus Quercetin, Teil-Reprogrammierung mit Yamanaka-Faktoren, ein Maus-Sehexperiment des Sinclair-Labors von 2020, NAD+ und Sirtuine sowie Herausforderungen wie Krebsrisiko. https://www.youtube-nocookie.com/embed/-Q_eSV70hsc 240 2026-01-11T14:30:00.000Z 2026-10-23T02:56:12.804Z https://longevityharbor.com/en/watch/-Sbco73Kh2s Multiple Aging Clocks: Which to Use and Why? https://i.ytimg.com/vi/-Sbco73Kh2s/hqdefault.jpg In this recorded webinar, you’ll explore the differences between aging clocks like OMICmAge, SYMPHONYAge, and DunedinPACE. Each clock serves a unique role in predicting health outcomes, from tracking multi-omic measurements for mortality to monitoring biomarkers for organ function and assessing the pace of aging. While they all predict biological age, they provide distinct insights, helping you decide which tool to use for optimal health management. Watch now to gain a deeper understanding of these innovative clocks! Google slides link here 👉 https://docs.google.com/presentation/d/1N8mj_Oe5NtEF5FOmuLkd6qvYBurvHHduZOEk1IuTzcU/edit 👉 𝗢𝗨𝗥 𝗧𝗥𝗨𝗔𝗚𝗘 𝗕𝗜𝗢𝗟𝗢𝗚𝗜𝗖𝗔𝗟 𝗔𝗚𝗘 𝗧𝗘𝗦𝗧 https://shop.trudiagnostic.com/products/truage-complete-epigenetic-collection 🔗 𝗦𝗢𝗖𝗜𝗔𝗟𝗦 + 𝗪𝗘𝗕𝗦𝗜𝗧𝗘 📸 Instagram - / https://www.instagram.com/trudiagnosticofficial/ 📱Facebook - / https://www.facebook.com/TruDiagnostic 🐦Twitter - / https://twitter.com/TruDiagnostic 🧪Website - www.trudiagnostic.com https://www.youtube-nocookie.com/embed/-Sbco73Kh2s 3092 2024-10-24T13:19:34.000Z 2026-10-22T19:43:52.061Z https://longevityharbor.com/de/watch/-Sbco73Kh2s Multiple Aging Clocks: Which to Use and Why? https://i.ytimg.com/vi/-Sbco73Kh2s/hqdefault.jpg In this recorded webinar, you’ll explore the differences between aging clocks like OMICmAge, SYMPHONYAge, and DunedinPACE. Each clock serves a unique role in predicting health outcomes, from tracking multi-omic measurements for mortality to monitoring biomarkers for organ function and assessing the pace of aging. While they all predict biological age, they provide distinct insights, helping you decide which tool to use for optimal health management. Watch now to gain a deeper understanding of these innovative clocks! Google slides link here 👉 https://docs.google.com/presentation/d/1N8mj_Oe5NtEF5FOmuLkd6qvYBurvHHduZOEk1IuTzcU/edit 👉 𝗢𝗨𝗥 𝗧𝗥𝗨𝗔𝗚𝗘 𝗕𝗜𝗢𝗟𝗢𝗚𝗜𝗖𝗔𝗟 𝗔𝗚𝗘 𝗧𝗘𝗦𝗧 https://shop.trudiagnostic.com/products/truage-complete-epigenetic-collection 🔗 𝗦𝗢𝗖𝗜𝗔𝗟𝗦 + 𝗪𝗘𝗕𝗦𝗜𝗧𝗘 📸 Instagram - / https://www.instagram.com/trudiagnosticofficial/ 📱Facebook - / https://www.facebook.com/TruDiagnostic 🐦Twitter - / https://twitter.com/TruDiagnostic 🧪Website - www.trudiagnostic.com https://www.youtube-nocookie.com/embed/-Sbco73Kh2s 3092 2024-10-24T13:19:34.000Z 2026-10-22T19:43:52.061Z https://longevityharbor.com/en/watch/-SyDLdjDCAk The Symphony of Aging: Dr. Raghav Sehgal on Epigenetic Clocks & Longevity https://i.ytimg.com/vi/-SyDLdjDCAk/hqdefault.jpg In this episode, Dr. Jeremy Koenig sits down with Dr. Raghav Sehgal, a Yale-trained computational biologist and longevity researcher, to uncover the science behind aging, resilience, and the future of preventative medicine. From his unconventional journey starting in electronics engineering in India to pioneering breakthroughs in epigenetic clocks and system-specific biomarkers of aging, Dr. Sehgal reveals how technology, biology, and proactive healthcare intersect to redefine longevity. Together, they explore how aging is not a single timeline but a complex symphony across 11 bodily systems, why resilience is as important as lifespan, and how interventions—from intermittent fasting to personalized medicine—can reshape healthspan. The conversation also dives into the limitations of reactive healthcare, the role of big pharma, and the promise of proactive, precision-based longevity science. Whether you’re a biohacker, physician, or someone curious about living not just longer but better, this episode offers insights into the future of aging research and human flourishing. ✨ Key Takeaways: 🧬 Aging is not one clock—it’s 11 interconnected systems that can be tuned like instruments. 🩺 Moving from reactive medicine to proactive longevity science is the key to healthier lives. 💊 Epigenetic clocks reveal how interventions like Ozempic and lifestyle changes target specific organ systems. ⚡ Resilience—your body’s ability to bounce back—is a stronger predictor of healthy aging than years alone. 🤝 Social connections and mental health are just as critical as diet, exercise, and sleep for longevity. 🥗 Intermittent fasting, diverse exercise, and preventative care are simple but powerful tools for better healthspan. 🌍 The future of medicine may include longevity clinics, personalized dashboards, and even gamification of aging. LINKS: https://www.drjeremykoenig.com/ https://www.instagram.com/drjeremykoenig/ https://www.youtube.com/@drjeremykoenig Here's the link for this week's episode: https://drjeremykoenig.s https://www.youtube-nocookie.com/embed/-SyDLdjDCAk 3368 2025-08-27T07:00:00.000Z 2026-10-22T19:21:27.758Z https://longevityharbor.com/de/watch/-SyDLdjDCAk The Symphony of Aging: Dr. Raghav Sehgal on Epigenetic Clocks & Longevity https://i.ytimg.com/vi/-SyDLdjDCAk/hqdefault.jpg In this episode, Dr. Jeremy Koenig sits down with Dr. Raghav Sehgal, a Yale-trained computational biologist and longevity researcher, to uncover the science behind aging, resilience, and the future of preventative medicine. From his unconventional journey starting in electronics engineering in India to pioneering breakthroughs in epigenetic clocks and system-specific biomarkers of aging, Dr. Sehgal reveals how technology, biology, and proactive healthcare intersect to redefine longevity. Together, they explore how aging is not a single timeline but a complex symphony across 11 bodily systems, why resilience is as important as lifespan, and how interventions—from intermittent fasting to personalized medicine—can reshape healthspan. The conversation also dives into the limitations of reactive healthcare, the role of big pharma, and the promise of proactive, precision-based longevity science. Whether you’re a biohacker, physician, or someone curious about living not just longer but better, this episode offers insights into the future of aging research and human flourishing. ✨ Key Takeaways: 🧬 Aging is not one clock—it’s 11 interconnected systems that can be tuned like instruments. 🩺 Moving from reactive medicine to proactive longevity science is the key to healthier lives. 💊 Epigenetic clocks reveal how interventions like Ozempic and lifestyle changes target specific organ systems. ⚡ Resilience—your body’s ability to bounce back—is a stronger predictor of healthy aging than years alone. 🤝 Social connections and mental health are just as critical as diet, exercise, and sleep for longevity. 🥗 Intermittent fasting, diverse exercise, and preventative care are simple but powerful tools for better healthspan. 🌍 The future of medicine may include longevity clinics, personalized dashboards, and even gamification of aging. LINKS: https://www.drjeremykoenig.com/ https://www.instagram.com/drjeremykoenig/ https://www.youtube.com/@drjeremykoenig Here's the link for this week's episode: https://drjeremykoenig.s https://www.youtube-nocookie.com/embed/-SyDLdjDCAk 3368 2025-08-27T07:00:00.000Z 2026-10-22T19:21:27.758Z https://longevityharbor.com/en/watch/-WjSuYJz9z4 Podcast talk on biological age tests, mTOR, calorie restriction and protein https://i.ytimg.com/vi/-WjSuYJz9z4/hqdefault.jpg In this English-language podcast episode, biologist Matt Kaeberlein discusses, according to the description, how useful biological age tests are, why mTOR is described as a central metabolic switch in aging, and how calorie restriction and protein intake relate to these pathways. https://www.youtube-nocookie.com/embed/-WjSuYJz9z4 5512 2025-12-30T04:00:00.000Z 2026-10-23T03:04:25.591Z https://longevityharbor.com/de/watch/-WjSuYJz9z4 Podcast-Gespräch über biologische Alterstests, mTOR, Kalorienrestriktion und Protein https://i.ytimg.com/vi/-WjSuYJz9z4/hqdefault.jpg In dieser englischsprachigen Podcast-Folge spricht Biologe Matt Kaeberlein laut Beschreibung darüber, wie sinnvoll Tests zum biologischen Alter sind, warum mTOR als zentraler Stoffwechselschalter im Altern gilt und wie Kalorienrestriktion und Proteinzufuhr mit diesen Signalwegen zusammenhängen. https://www.youtube-nocookie.com/embed/-WjSuYJz9z4 5512 2025-12-30T04:00:00.000Z 2026-10-23T03:04:25.591Z https://longevityharbor.com/en/watch/-_2Z8I1sdvw Video description: theobromine and slower epigenetic ageing in two human cohorts https://i.ytimg.com/vi/-_2Z8I1sdvw/hqdefault.jpg The description reports a 2025 study linking higher theobromine levels to slower epigenetic ageing in two human cohorts, while stating this does not prove that eating dark chocolate slows ageing. https://www.youtube-nocookie.com/embed/-_2Z8I1sdvw 91 2026-09-10T08:24:42.000Z 2026-10-22T22:19:03.224Z https://longevityharbor.com/de/watch/-_2Z8I1sdvw Videobeschreibung: Theobromin und langsameres epigenetisches Altern in zwei Kohorten https://i.ytimg.com/vi/-_2Z8I1sdvw/hqdefault.jpg Die Beschreibung berichtet von einer Studie aus 2025, die höhere Theobrominwerte mit langsameren epigenetischem Altern in zwei menschlichen Kohorten verknüpft, und betont, dass dies nicht beweist, dass dunkle Schokolade das Altern verlangsamt. https://www.youtube-nocookie.com/embed/-_2Z8I1sdvw 91 2026-09-10T08:24:42.000Z 2026-10-22T22:19:03.224Z https://longevityharbor.com/en/watch/-bOTIKEBG54 Dr. Raul Mostoslavsky - SIRT6 and The Hallmarks of Aging https://i.ytimg.com/vi/-bOTIKEBG54/hqdefault.jpg In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Raul Mostoslavsky, the Laurel Schwartz Professor of Oncology at Harvard Medical School. Dr. Raul Mostoslavsky has studied sirtuin functions in cancer for many years and has identified a pathway responsible for tumor growth in 30% to 40% of pancreatic cancer patients and more recently identified metabolism as a heterogeneous feature of cancer. Dr. Raul Mostoslavsky discusses the role of sirtuins in aging and explains how the mechanisms that protect us from cancer may also preserve our longevity on a cellular level. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast — Let’s Connect! Instagram - https://www.instagram.com/insidetracker Twitter - https://twitter.com/InsideTracker Facebook - https://www.facebook.com/InsideTracker LinkedIn- https://www.linkedin.com/company/insidetracker/  TikTok- https://www.tiktok.com/@insidetracker_  Pinterest- https://www.pinterest.com/insidetracker/  Website - https://www.insidetracker.com/  In the Press - https://www.insidetracker.com/press-page/ https://www.youtube-nocookie.com/embed/-bOTIKEBG54 3626 2022-03-25T13:41:51.000Z 2026-10-22T17:43:39.321Z https://longevityharbor.com/de/watch/-bOTIKEBG54 Dr. Raul Mostoslavsky - SIRT6 and The Hallmarks of Aging https://i.ytimg.com/vi/-bOTIKEBG54/hqdefault.jpg In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Raul Mostoslavsky, the Laurel Schwartz Professor of Oncology at Harvard Medical School. Dr. Raul Mostoslavsky has studied sirtuin functions in cancer for many years and has identified a pathway responsible for tumor growth in 30% to 40% of pancreatic cancer patients and more recently identified metabolism as a heterogeneous feature of cancer. Dr. Raul Mostoslavsky discusses the role of sirtuins in aging and explains how the mechanisms that protect us from cancer may also preserve our longevity on a cellular level. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast — Let’s Connect! Instagram - https://www.instagram.com/insidetracker Twitter - https://twitter.com/InsideTracker Facebook - https://www.facebook.com/InsideTracker LinkedIn- https://www.linkedin.com/company/insidetracker/  TikTok- https://www.tiktok.com/@insidetracker_  Pinterest- https://www.pinterest.com/insidetracker/  Website - https://www.insidetracker.com/  In the Press - https://www.insidetracker.com/press-page/ https://www.youtube-nocookie.com/embed/-bOTIKEBG54 3626 2022-03-25T13:41:51.000Z 2026-10-22T17:43:39.321Z https://longevityharbor.com/en/watch/-dNM35NNypk Webinar description: intermittent fasting, meal timing and metabolic health https://i.ytimg.com/vi/-dNM35NNypk/hqdefault.jpg The description announces a webinar in which Dr. Altonji discusses what intermittent fasting is, how its main approaches differ, and what research shows about skipping breakfast, eating later in the evening, blood sugar, cardiovascular risk factors, weight management and healthy aging. https://www.youtube-nocookie.com/embed/-dNM35NNypk 3397 2026-05-28T19:31:25.000Z 2026-10-23T00:18:46.370Z https://longevityharbor.com/de/watch/-dNM35NNypk Webinar-Beschreibung: Intervallfasten, Essenszeiten und Stoffwechselgesundheit https://i.ytimg.com/vi/-dNM35NNypk/hqdefault.jpg Die Beschreibung kündigt ein Webinar an, in dem Dr. Altonji erklärt, was Intervallfasten ist, wie sich die wichtigsten Ansätze unterscheiden und was die Forschung zu ausgelassenem Frühstück, späterem Essen am Abend, Blutzucker, Herz-Kreislauf-Risikofaktoren, Gewichtsmanagement und gesundem Altern zeigt. https://www.youtube-nocookie.com/embed/-dNM35NNypk 3397 2026-05-28T19:31:25.000Z 2026-10-23T00:18:46.370Z https://longevityharbor.com/en/watch/-ujIfZXGbDA Does this Dog Supplement Really Work to REVERSE AGE? (PART 1) | 19 - Longevity This Week #3 (1/2) https://i.ytimg.com/vi/-ujIfZXGbDA/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Part II: https://youtu.be/Xu1H2lECbBs When drug development companies promote their products, they understandably highlight the benefits and potential relief they offer. While these advertisements can make the products seem like game-changers for health issues, it's important not to swallow the marketing spiel whole. Question it, test it, poke and prod it to see if it holds up under scrutiny. Take the time to research the drug independently and examine what the press release or advertisement claims. Look for unbiased sources like medical journals, regulatory agencies, or reputable health websites that might provide a more balanced view of the drug's efficacy and safety. Part of our mission at the Optispan Podcast is to encourage critical thinking about science, including and especially science related to health- and lifespan. In this episode, Matt puts the spotlight on a recent press release that made a splash in the longevity community: an announcement of a combination senolytic/NAD booster product that researchers suggested has the potential to reverse age-related decline in dogs. Matt goes over claims the press release and the researchers make, what the product might contain (spoiler: we're not sure), what we do and don't know about it, and his personal feelings about whether it should actually be on the market for pet owners to purchase. This episode is Part I of a two-part series. In part II, Matt will go deeper into the actual research behind claims in the press release and examine how well it withstands critical evaluation. 0:00 Trailer 0:42 Introduction 2:32 bioRxiv primer 4:05 Troubling press release claim #1 5:30 Troubling press release claim #2 6:20 Troubling press release claim #3 6:22 The most egregious quote 8:14 Tackling the aging of companion animals as a goal 9:59 What's in the Animal Biosciences product "LeapYears"? 12:06 Are the molecules in the product good for dog life- and/or healthspan? 21:33 Takeaways Producers: Tara Mei, Ni https://www.youtube-nocookie.com/embed/-ujIfZXGbDA 1396 2024-03-27T14:00:00.000Z 2026-10-22T19:54:20.292Z https://longevityharbor.com/de/watch/-ujIfZXGbDA Does this Dog Supplement Really Work to REVERSE AGE? (PART 1) | 19 - Longevity This Week #3 (1/2) https://i.ytimg.com/vi/-ujIfZXGbDA/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Part II: https://youtu.be/Xu1H2lECbBs When drug development companies promote their products, they understandably highlight the benefits and potential relief they offer. While these advertisements can make the products seem like game-changers for health issues, it's important not to swallow the marketing spiel whole. Question it, test it, poke and prod it to see if it holds up under scrutiny. Take the time to research the drug independently and examine what the press release or advertisement claims. Look for unbiased sources like medical journals, regulatory agencies, or reputable health websites that might provide a more balanced view of the drug's efficacy and safety. Part of our mission at the Optispan Podcast is to encourage critical thinking about science, including and especially science related to health- and lifespan. In this episode, Matt puts the spotlight on a recent press release that made a splash in the longevity community: an announcement of a combination senolytic/NAD booster product that researchers suggested has the potential to reverse age-related decline in dogs. Matt goes over claims the press release and the researchers make, what the product might contain (spoiler: we're not sure), what we do and don't know about it, and his personal feelings about whether it should actually be on the market for pet owners to purchase. This episode is Part I of a two-part series. In part II, Matt will go deeper into the actual research behind claims in the press release and examine how well it withstands critical evaluation. 0:00 Trailer 0:42 Introduction 2:32 bioRxiv primer 4:05 Troubling press release claim #1 5:30 Troubling press release claim #2 6:20 Troubling press release claim #3 6:22 The most egregious quote 8:14 Tackling the aging of companion animals as a goal 9:59 What's in the Animal Biosciences product "LeapYears"? 12:06 Are the molecules in the product good for dog life- and/or healthspan? 21:33 Takeaways Producers: Tara Mei, Ni https://www.youtube-nocookie.com/embed/-ujIfZXGbDA 1396 2024-03-27T14:00:00.000Z 2026-10-22T19:54:20.292Z https://longevityharbor.com/en/watch/-umfAzgU0KI Epigenetische Reprogrammierung – Prof. Dr. Björn Schumacher über die Verjüngung von Zellen https://i.ytimg.com/vi/-umfAzgU0KI/hqdefault.jpg In diesem Podcast spreche ich erneut mit Prof. Dr. Björn Schumacher vom CECAD Forschungszentrum der Uni Köln. Bereits letzte Woche hat Prof. Schumacher uns in die Welt der Epigenetik und den Forschungsstand der epigenetischen Uhren aufgeklärt. Heute sprechen wir konkret über die epigenetische Reprogrammierung und die Yamanaka-Faktoren. In dieser Folge behandeln wir folgende Fragen: - Wie funktioniert epigenetische Reprogrammierung? - Wie können die Stoppschilder der Zelle neu programmiert werden? - Was sind Yamanaka-Faktoren? - Wie weit ist die Forschung? - Welche Krankheiten könnten hiermit geheilt werden? Weitere Informationen zu Prof. Dr. Björn Schumacher findest du hier: https://www.cecad.uni-koeln.de/research/principal-investigators/full-members/bjoern-schumacher Die Folge mit Prof. Dr. Schumacher zur Epigenetik findest du hier: https://link.stayoung.de/STY-114 Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder Youtube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an deinen Arzt/deine Ärztin. STY-112 https://www.youtube-nocookie.com/embed/-umfAzgU0KI 2214 2024-08-23T04:00:07.000Z 2026-10-22T17:11:30.659Z https://longevityharbor.com/de/watch/-umfAzgU0KI Epigenetische Reprogrammierung – Prof. Dr. Björn Schumacher über die Verjüngung von Zellen https://i.ytimg.com/vi/-umfAzgU0KI/hqdefault.jpg In diesem Podcast spreche ich erneut mit Prof. Dr. Björn Schumacher vom CECAD Forschungszentrum der Uni Köln. Bereits letzte Woche hat Prof. Schumacher uns in die Welt der Epigenetik und den Forschungsstand der epigenetischen Uhren aufgeklärt. Heute sprechen wir konkret über die epigenetische Reprogrammierung und die Yamanaka-Faktoren. In dieser Folge behandeln wir folgende Fragen: - Wie funktioniert epigenetische Reprogrammierung? - Wie können die Stoppschilder der Zelle neu programmiert werden? - Was sind Yamanaka-Faktoren? - Wie weit ist die Forschung? - Welche Krankheiten könnten hiermit geheilt werden? Weitere Informationen zu Prof. Dr. Björn Schumacher findest du hier: https://www.cecad.uni-koeln.de/research/principal-investigators/full-members/bjoern-schumacher Die Folge mit Prof. Dr. Schumacher zur Epigenetik findest du hier: https://link.stayoung.de/STY-114 Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder Youtube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an deinen Arzt/deine Ärztin. STY-112 https://www.youtube-nocookie.com/embed/-umfAzgU0KI 2214 2024-08-23T04:00:07.000Z 2026-10-22T17:11:30.659Z https://longevityharbor.com/en/watch/0-YwCD_xFG8 Video description on metformin, rapamycin and semaglutide in anti-aging research https://i.ytimg.com/vi/0-YwCD_xFG8/hqdefault.jpg According to the description, dermatologist Dr. med. Robert Kasten explains the current study situation on metformin, rapamycin and semaglutide (Ozempic) in anti-aging research, without exaggeration; he states he does not prescribe these drugs or advise on them in his practice. https://www.youtube-nocookie.com/embed/0-YwCD_xFG8 496 2026-04-04T22:00:00.000Z 2026-10-23T01:45:06.964Z https://longevityharbor.com/de/watch/0-YwCD_xFG8 Videobeschreibung zu Metformin, Rapamycin und Semaglutid in der Anti-Aging-Forschung https://i.ytimg.com/vi/0-YwCD_xFG8/hqdefault.jpg Laut Beschreibung erklärt der Dermatologe Dr. med. Robert Kasten die aktuelle Studienlage zu Metformin, Rapamycin und Semaglutid (Ozempic) in der Anti-Aging-Forschung, ohne Übertreibung; er gibt an, diese Medikamente in seiner Praxis nicht zu verschreiben und dazu nicht zu beraten. https://www.youtube-nocookie.com/embed/0-YwCD_xFG8 496 2026-04-04T22:00:00.000Z 2026-10-23T01:45:06.964Z https://longevityharbor.com/en/watch/0-l35R-kuxk Video description compares Cata-Kor NMN capsule and powder https://i.ytimg.com/vi/0-l35R-kuxk/hqdefault.jpg The description asks about the difference between Cata-Kor's NMN capsule and the powder, but gives no ingredients, doses or comparison results; it only links to product pages. https://www.youtube-nocookie.com/embed/0-l35R-kuxk 127 2026-09-02T23:47:31.000Z 2026-10-22T22:30:49.742Z https://longevityharbor.com/de/watch/0-l35R-kuxk Videobeschreibung vergleicht Cata-Kor-NMN-Kapsel und -Pulver https://i.ytimg.com/vi/0-l35R-kuxk/hqdefault.jpg Die Beschreibung fragt nach dem Unterschied zwischen Cata-Kors NMN-Kapsel und dem Pulver, nennt aber keine Inhaltsstoffe, Dosierungen oder Vergleichsergebnisse; sie verlinkt nur auf Produktseiten. https://www.youtube-nocookie.com/embed/0-l35R-kuxk 127 2026-09-02T23:47:31.000Z 2026-10-22T22:30:49.742Z https://longevityharbor.com/en/watch/03wio1l4QMQ Die besten Beinstärkungsübungen für Senioren https://i.ytimg.com/vi/03wio1l4QMQ/hqdefault.jpg 🎓 Willkommen im exklusiven Mitgliederbereich von SeniorenGesundheit+! Hier erhalten Sie jede Woche neue Trainingsprogramme, ausführliche PDF-Leitfäden, exklusive Videos und Schritt-für-Schritt-Erklärungen, die auf YouTube nicht verfügbar sind. Alle Inhalte basieren auf aktueller Physiotherapie und wissenschaftlichen Erkenntnissen und wurden speziell entwickelt, um Menschen ab 60 dabei zu helfen, länger aktiv, mobil und selbstständig zu bleiben. 👉 Jetzt Mitglied werden: https://www.patreon.com/cw/SeniorenGesundheit Starke Beine ab 60 sind kein Zufall. In diesem Video zeige ich drei einfache, aber extrem wirksame Übungen für Senioren, die gezielt die wichtigsten Muskeln für Stabilität, Balance und sicheres Gehen aktivieren. Diese Routine stärkt Fußmuskeln, Unterschenkel und die gesamte Beinachse – perfekt für Senioren-Gesundheit, bessere Mobilität und mehr Sicherheit im Alltag. Ideal für alle, die leichter gehen, länger stehen und ihre Beinkraft spürbar verbessern möchten. Regelmäßig durchgeführt, unterstützen diese Übungen: • bessere Beinstabilität • sicherere Schritte • weniger Müdigkeit in den Beinen • gesundes, aktives Gehen im Alter Bleib aktiv – deine Beine tragen dich durchs ganze Leben. #gesundheit #senioren #seniorengesundheit #übungen Disclaimer: Die Videos auf diesem Kanal bieten allgemeine Informationen zur Seniorengesundheit, sind jedoch keine medizinische Beratung. Bei gesundheitlichen Problemen konsultieren Sie bitte immer einen Arzt. Wir übernehmen keine Haftung für die Anwendung der gezeigten Inhalte. https://www.youtube-nocookie.com/embed/03wio1l4QMQ 373 2025-11-27T13:03:56.000Z 2026-10-22T19:21:28.597Z https://longevityharbor.com/de/watch/03wio1l4QMQ Die besten Beinstärkungsübungen für Senioren https://i.ytimg.com/vi/03wio1l4QMQ/hqdefault.jpg 🎓 Willkommen im exklusiven Mitgliederbereich von SeniorenGesundheit+! Hier erhalten Sie jede Woche neue Trainingsprogramme, ausführliche PDF-Leitfäden, exklusive Videos und Schritt-für-Schritt-Erklärungen, die auf YouTube nicht verfügbar sind. Alle Inhalte basieren auf aktueller Physiotherapie und wissenschaftlichen Erkenntnissen und wurden speziell entwickelt, um Menschen ab 60 dabei zu helfen, länger aktiv, mobil und selbstständig zu bleiben. 👉 Jetzt Mitglied werden: https://www.patreon.com/cw/SeniorenGesundheit Starke Beine ab 60 sind kein Zufall. In diesem Video zeige ich drei einfache, aber extrem wirksame Übungen für Senioren, die gezielt die wichtigsten Muskeln für Stabilität, Balance und sicheres Gehen aktivieren. Diese Routine stärkt Fußmuskeln, Unterschenkel und die gesamte Beinachse – perfekt für Senioren-Gesundheit, bessere Mobilität und mehr Sicherheit im Alltag. Ideal für alle, die leichter gehen, länger stehen und ihre Beinkraft spürbar verbessern möchten. Regelmäßig durchgeführt, unterstützen diese Übungen: • bessere Beinstabilität • sicherere Schritte • weniger Müdigkeit in den Beinen • gesundes, aktives Gehen im Alter Bleib aktiv – deine Beine tragen dich durchs ganze Leben. #gesundheit #senioren #seniorengesundheit #übungen Disclaimer: Die Videos auf diesem Kanal bieten allgemeine Informationen zur Seniorengesundheit, sind jedoch keine medizinische Beratung. Bei gesundheitlichen Problemen konsultieren Sie bitte immer einen Arzt. Wir übernehmen keine Haftung für die Anwendung der gezeigten Inhalte. https://www.youtube-nocookie.com/embed/03wio1l4QMQ 373 2025-11-27T13:03:56.000Z 2026-10-22T19:21:28.597Z https://longevityharbor.com/en/watch/05OcR_Tki0Q 2024 - Precision Health & Longevity Summit (8/15) https://i.ytimg.com/vi/05OcR_Tki0Q/hqdefault.jpg Speech Part 1/8 https://www.youtube-nocookie.com/embed/05OcR_Tki0Q 1904 2026-02-04T20:42:16.000Z 2026-10-22T19:32:34.312Z https://longevityharbor.com/de/watch/05OcR_Tki0Q 2024 - Precision Health & Longevity Summit (8/15) https://i.ytimg.com/vi/05OcR_Tki0Q/hqdefault.jpg Speech Part 1/8 https://www.youtube-nocookie.com/embed/05OcR_Tki0Q 1904 2026-02-04T20:42:16.000Z 2026-10-22T19:32:34.312Z https://longevityharbor.com/en/watch/06TkxF8VITw Senescent Cell Expert : Big Pharma Walked Away, But The Future Is Bright https://i.ytimg.com/vi/06TkxF8VITw/hqdefault.jpg Senescent cells were supposed to be the "easy" target in aging research—clear them out and extend healthspan. But new research reveals the field is far more complex than anyone imagined, with major clinical trial setbacks forcing scientists to completely rethink their approach. Some links are affiliate links so we will earn a commission when they are used to purchase products. I--------------------- If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan *Renue By Science* (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR *BiOptimizers* (15% off: Modern10) https://bit.ly/42OqRVW - Magnesium Breakthrough *Stemregen* (15% off: MODERN) *US only* https://tinyurl.com/45z968yr *Qualia* (15% off: MODERN) Senolytic: https://tinyurl.com/22t9thrn • Mind: https://tinyurl.com/5hatj2t2 *Life Extension* ($10 off $50 order) NAC: https://tinyurl.com/vzvbde99 • Ergothioneine 25mg https://tinyurl.com/48h2bnst *NOVOS* ($5 off: 5OFFMHS24) https://novos.sjv.io/QyWP7o, https://novos.sjv.io/NOVOS *n1o1* (10% off: Modern) https://tidd.ly/3IczGRW - Nitric Oxide Lozenges *Wellness Extract* (10% off: MODERNWE) http://wellnessextract.com/RICHARDWE Geranylgeraniol • Vit E *AX3 Life* (20% off: MODERN20) https://ax3.life/MODERN20 - Astaxanthin *Oxford Healthspan* (15% off: MHS) https://tinyurl.com/hrxfnzpn - Spermidine *Nuchido* (20% off first order: MODERN20) https://nuchido.com/MODERN - Time+ --------------------- In this conversation with Dr. Paul Robbins from the University of Minnesota, we explore the evolving world of senescent cell research and senolytics—drugs designed to clear "zombie" cells from our bodies. Dr. Robbins reveals how recent research shows senescence is far more complex than expected, with different types arising from different stresses. We discuss why Unity Biotech's trials failed, mixed results from fisetin studies, and surprising positive signals from Mayo Clinic trials in patients with high senescent cell burden. He explains why future trea https://www.youtube-nocookie.com/embed/06TkxF8VITw 3537 2025-08-24T13:07:49.000Z 2026-10-22T19:21:23.157Z https://longevityharbor.com/de/watch/06TkxF8VITw Senescent Cell Expert : Big Pharma Walked Away, But The Future Is Bright https://i.ytimg.com/vi/06TkxF8VITw/hqdefault.jpg Senescent cells were supposed to be the "easy" target in aging research—clear them out and extend healthspan. But new research reveals the field is far more complex than anyone imagined, with major clinical trial setbacks forcing scientists to completely rethink their approach. Some links are affiliate links so we will earn a commission when they are used to purchase products. I--------------------- If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan *Renue By Science* (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR *BiOptimizers* (15% off: Modern10) https://bit.ly/42OqRVW - Magnesium Breakthrough *Stemregen* (15% off: MODERN) *US only* https://tinyurl.com/45z968yr *Qualia* (15% off: MODERN) Senolytic: https://tinyurl.com/22t9thrn • Mind: https://tinyurl.com/5hatj2t2 *Life Extension* ($10 off $50 order) NAC: https://tinyurl.com/vzvbde99 • Ergothioneine 25mg https://tinyurl.com/48h2bnst *NOVOS* ($5 off: 5OFFMHS24) https://novos.sjv.io/QyWP7o, https://novos.sjv.io/NOVOS *n1o1* (10% off: Modern) https://tidd.ly/3IczGRW - Nitric Oxide Lozenges *Wellness Extract* (10% off: MODERNWE) http://wellnessextract.com/RICHARDWE Geranylgeraniol • Vit E *AX3 Life* (20% off: MODERN20) https://ax3.life/MODERN20 - Astaxanthin *Oxford Healthspan* (15% off: MHS) https://tinyurl.com/hrxfnzpn - Spermidine *Nuchido* (20% off first order: MODERN20) https://nuchido.com/MODERN - Time+ --------------------- In this conversation with Dr. Paul Robbins from the University of Minnesota, we explore the evolving world of senescent cell research and senolytics—drugs designed to clear "zombie" cells from our bodies. Dr. Robbins reveals how recent research shows senescence is far more complex than expected, with different types arising from different stresses. We discuss why Unity Biotech's trials failed, mixed results from fisetin studies, and surprising positive signals from Mayo Clinic trials in patients with high senescent cell burden. He explains why future trea https://www.youtube-nocookie.com/embed/06TkxF8VITw 3537 2025-08-24T13:07:49.000Z 2026-10-22T19:21:23.157Z https://longevityharbor.com/en/watch/07fNPovQnd4 Longevity Science 2024: New Insights on "The Hallmarks of Aging" & What They Mean | 14 - LS #5 https://i.ytimg.com/vi/07fNPovQnd4/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Over a decade ago, five researchers published a paper proposing the Hallmarks of Aging paradigm: a set of cellular and molecular processes that underlie the aging process in different organisms. These hallmarks encompass a range of interconnected pathways, including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient signaling, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis. Together, the hallmarks contribute to the gradual decline in physiological function and increased susceptibility to age-related diseases that occurs with age, and provide a framework for understanding how we age. In this episode, Matt takes us through a quick download of each hallmark of aging, talks about some of the paradigm's shortcomings and limitations, and discusses the implications of the Hallmarks of Aging paradigm for the geroscience field. 0:00 Trailer 0:44 Introduction 2:30 Definition of the hallmarks of aging 4:40 Criteria 1: Age-associated manifestation 6:43 Criticisms of the hallmarks of aging 8:36 The current version of the hallmarks of aging 9:00 Genomic instability 10:27 Telomere attrition 12:40 Epigenetic alterations 15:32 Loss of proteostasis 17:40 Disabled macroautophagy 20:17 Deregulated nutrient signaling 21:57 Mitochondrial dysfunction 23:13 Cellular senescence 27:13 Stem cell exhaustion 29:50 Altered intercellular communication 30:47 Chronic inflammation + "inflammaging" 32:09 Dysbiosis 33:43 The interconnectedness of hallmarks 35:48 Our rudimentary understanding of biological aging 40:37 Advice for the field 40:48 Pillars of aging and their impact on the aging process Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor s https://www.youtube-nocookie.com/embed/07fNPovQnd4 2611 2024-03-11T11:00:51.000Z 2026-10-22T17:43:40.092Z https://longevityharbor.com/de/watch/07fNPovQnd4 Longevity Science 2024: New Insights on "The Hallmarks of Aging" & What They Mean | 14 - LS #5 https://i.ytimg.com/vi/07fNPovQnd4/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Over a decade ago, five researchers published a paper proposing the Hallmarks of Aging paradigm: a set of cellular and molecular processes that underlie the aging process in different organisms. These hallmarks encompass a range of interconnected pathways, including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient signaling, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis. Together, the hallmarks contribute to the gradual decline in physiological function and increased susceptibility to age-related diseases that occurs with age, and provide a framework for understanding how we age. In this episode, Matt takes us through a quick download of each hallmark of aging, talks about some of the paradigm's shortcomings and limitations, and discusses the implications of the Hallmarks of Aging paradigm for the geroscience field. 0:00 Trailer 0:44 Introduction 2:30 Definition of the hallmarks of aging 4:40 Criteria 1: Age-associated manifestation 6:43 Criticisms of the hallmarks of aging 8:36 The current version of the hallmarks of aging 9:00 Genomic instability 10:27 Telomere attrition 12:40 Epigenetic alterations 15:32 Loss of proteostasis 17:40 Disabled macroautophagy 20:17 Deregulated nutrient signaling 21:57 Mitochondrial dysfunction 23:13 Cellular senescence 27:13 Stem cell exhaustion 29:50 Altered intercellular communication 30:47 Chronic inflammation + "inflammaging" 32:09 Dysbiosis 33:43 The interconnectedness of hallmarks 35:48 Our rudimentary understanding of biological aging 40:37 Advice for the field 40:48 Pillars of aging and their impact on the aging process Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor s https://www.youtube-nocookie.com/embed/07fNPovQnd4 2611 2024-03-11T11:00:51.000Z 2026-10-22T17:43:40.092Z https://longevityharbor.com/en/watch/08JEGaLxh1s This One Exercise Strengthens Your Legs Faster Than the Gym https://i.ytimg.com/vi/08JEGaLxh1s/hqdefault.jpg Welcome to Feynman Longevity — your guide to the science of healthy aging and longevity! Explore the science behind the human body, muscle strength, blood circulation, nutrition, mobility, and healthy aging. Our goal is to make complex health science easy to understand through educational content inspired by scientific research. Discover evidence-informed insights to help you better understand your body and learn more about healthy aging, daily habits, and long-term well-being. 🔔 Subscribe to Feynman Longevity for more educational videos on longevity, human biology, and health science. ⚠️ Disclaimer: This video is for educational and informational purposes only. It is not medical advice and does not replace professional medical diagnosis or treatment. Always consult a qualified healthcare professional regarding personal health concerns. #FeynmanLongevity #HealthyAging #Longevity #HealthScience #HumanBody #HealthyLiving #AgingWell #Nutrition #BloodCirculation #MuscleStrength https://www.youtube-nocookie.com/embed/08JEGaLxh1s 1656 2026-10-22T14:30:01.000Z 2026-10-22T19:54:15.746Z https://longevityharbor.com/de/watch/08JEGaLxh1s This One Exercise Strengthens Your Legs Faster Than the Gym https://i.ytimg.com/vi/08JEGaLxh1s/hqdefault.jpg Welcome to Feynman Longevity — your guide to the science of healthy aging and longevity! Explore the science behind the human body, muscle strength, blood circulation, nutrition, mobility, and healthy aging. Our goal is to make complex health science easy to understand through educational content inspired by scientific research. Discover evidence-informed insights to help you better understand your body and learn more about healthy aging, daily habits, and long-term well-being. 🔔 Subscribe to Feynman Longevity for more educational videos on longevity, human biology, and health science. ⚠️ Disclaimer: This video is for educational and informational purposes only. It is not medical advice and does not replace professional medical diagnosis or treatment. Always consult a qualified healthcare professional regarding personal health concerns. #FeynmanLongevity #HealthyAging #Longevity #HealthScience #HumanBody #HealthyLiving #AgingWell #Nutrition #BloodCirculation #MuscleStrength https://www.youtube-nocookie.com/embed/08JEGaLxh1s 1656 2026-10-22T14:30:01.000Z 2026-10-22T19:54:15.746Z https://longevityharbor.com/en/watch/0CgvUGCyAec Podcast description: fasting mimicking diet, midlife and Prolon https://i.ytimg.com/vi/0CgvUGCyAec/hqdefault.jpg The description presents a podcast episode in which Renee Fitton of Prolon explains the fasting mimicking diet, autophagy, protein advice and midlife nutrition; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/0CgvUGCyAec 2429 2026-06-17T08:00:17.000Z 2026-10-22T23:57:27.709Z https://longevityharbor.com/de/watch/0CgvUGCyAec Podcast-Beschreibung: Fasten-imitierende Diät, Lebensmitte und Prolon https://i.ytimg.com/vi/0CgvUGCyAec/hqdefault.jpg Die Beschreibung stellt eine Podcast-Folge vor, in der Renee Fitton von Prolon die fasten-imitierende Diät, Autophagie, Eiweißempfehlungen und Ernährung in der Lebensmitte erklärt; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/0CgvUGCyAec 2429 2026-06-17T08:00:17.000Z 2026-10-22T23:57:27.709Z https://longevityharbor.com/en/watch/0DFg9fAgl4Y Video description: five home glute exercises proposed for adults over 60 https://i.ytimg.com/vi/0DFg9fAgl4Y/hqdefault.jpg The description says the video presents five home exercises for adults over 60, ranked from beginner activation to the most powerful, aiming to improve stability and reduce fall risk. It cites research sources but reports no study results of its own. https://www.youtube-nocookie.com/embed/0DFg9fAgl4Y 1324 2026-02-13T20:53:24.000Z 2026-10-23T02:35:23.691Z https://longevityharbor.com/de/watch/0DFg9fAgl4Y Videobeschreibung: fünf häusliche Gesäßübungen für Erwachsene über 60 vorgeschlagen https://i.ytimg.com/vi/0DFg9fAgl4Y/hqdefault.jpg Laut Beschreibung zeigt das Video fünf häusliche Übungen für Erwachsene über 60, geordnet von einfacher Aktivierung bis zur stärksten Übung, mit dem Ziel, Stabilität zu verbessern und das Sturzrisiko zu senken. Es nennt Forschungsquellen, berichtet aber keine eigenen Studienergebnisse. https://www.youtube-nocookie.com/embed/0DFg9fAgl4Y 1324 2026-02-13T20:53:24.000Z 2026-10-23T02:35:23.691Z https://longevityharbor.com/en/watch/0GWSrv90BpE Role of Sleep, Exercise, and Food in Healthy Aging and Longevity: Science-Backed Lifestyle Essential https://i.ytimg.com/vi/0GWSrv90BpE/hqdefault.jpg "Role of Sleep, Exercise, and Food in Healthy Aging and Longevity: Science-Backed Lifestyle Essentials 2025 Discover how balanced sleep, regular exercise, and nutritious food synergistically promote healthy aging and extend longevity. Quality sleep supports metabolic health, brain function, and cellular repair, while physical activity maintains muscle mass, cardiovascular fitness, and functional independence. Nutrition rich in antioxidants, proteins, and essential vitamins fuels immune response, reduces inflammation, and protects against chronic diseases. This 2025 guide presents science-backed strategies showing how integrating these lifestyle pillars can enhance healthspan, prevent age-related decline, and help you live a longer, vibrant life. #healthyaging #longevity #sleephealth #physicalactivity #nutrition #antiaging #wellness #fitness #healthylifestyle #agingwell sleep and healthy aging, exercise longevity benefits, nutrition for aging, role of physical activity in aging, dietary antioxidants aging, muscle health aging, metabolic health longevity, circadian rhythm aging, healthy diet for longevity, Mediterranean diet aging, protein intake aging, cardiovascular health exercise, sleep quality and longevity, anti aging lifestyle tips, chronic disease prevention aging, immune support nutrition aging, stress management aging, fitness and cognitive health aging, longevity lifestyle factors " https://www.youtube-nocookie.com/embed/0GWSrv90BpE 116 2025-09-13T02:00:02.000Z 2026-10-22T19:43:48.754Z https://longevityharbor.com/de/watch/0GWSrv90BpE Role of Sleep, Exercise, and Food in Healthy Aging and Longevity: Science-Backed Lifestyle Essential https://i.ytimg.com/vi/0GWSrv90BpE/hqdefault.jpg "Role of Sleep, Exercise, and Food in Healthy Aging and Longevity: Science-Backed Lifestyle Essentials 2025 Discover how balanced sleep, regular exercise, and nutritious food synergistically promote healthy aging and extend longevity. Quality sleep supports metabolic health, brain function, and cellular repair, while physical activity maintains muscle mass, cardiovascular fitness, and functional independence. Nutrition rich in antioxidants, proteins, and essential vitamins fuels immune response, reduces inflammation, and protects against chronic diseases. This 2025 guide presents science-backed strategies showing how integrating these lifestyle pillars can enhance healthspan, prevent age-related decline, and help you live a longer, vibrant life. #healthyaging #longevity #sleephealth #physicalactivity #nutrition #antiaging #wellness #fitness #healthylifestyle #agingwell sleep and healthy aging, exercise longevity benefits, nutrition for aging, role of physical activity in aging, dietary antioxidants aging, muscle health aging, metabolic health longevity, circadian rhythm aging, healthy diet for longevity, Mediterranean diet aging, protein intake aging, cardiovascular health exercise, sleep quality and longevity, anti aging lifestyle tips, chronic disease prevention aging, immune support nutrition aging, stress management aging, fitness and cognitive health aging, longevity lifestyle factors " https://www.youtube-nocookie.com/embed/0GWSrv90BpE 116 2025-09-13T02:00:02.000Z 2026-10-22T19:43:48.754Z https://longevityharbor.com/en/watch/0IIAWa5GZC4 Epigenetic Clocks for Testing Your Biological Age https://i.ytimg.com/vi/0IIAWa5GZC4/hqdefault.jpg Epigenetic clocks have become established as robust measures of chronological age, surpassing telomere length as the best age predictor. In addition to predicting time-to-death, epigenetic clocks also appear to foretell healthspan indicators, such as cognitive decline, frailty, arthritis, and the progression of diseases like Alzheimer’s and Parkinson’s. What are telomeres? See What to Eat to Prevent Telomere Shortening (https://nutritionfacts.org/video/what-to-eat-to-prevent-telomere-shortening/). For more on epigenetics and disease, see my videos The Role of Epigenetics in the Obesity Epidemic (https://nutritionfacts.org/video/the-role-of-epigenetics-in-the-obesity-epidemic/) and Animal Protein, Pregnancy, and Childhood Obesity (https://nutritionfacts.org/video/animal-protein-pregnancy-and-childhood-obesity/). For more on how to slow biological aging, check out my book How Not to Age (https://nutritionfacts.org/book/how-not-to-age/) from your local public library. If you haven’t seen them yet, check out the book trailer (https://nutritionfacts.org/video/book-trailer-for-how-not-to-age) and my new presentation (https://nutritionfacts.org/video/how-not-to-age-live-presentation/). (As always, all proceeds I receive from all of my books (https://nutritionfacts.org/books/) are donated to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/epigenetic-clocks-for-testing-your-biological-age and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/epigenetic-clocks-for-testing-your-biological-age. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 h https://www.youtube-nocookie.com/embed/0IIAWa5GZC4 357 2024-08-28T11:59:52.000Z 2026-10-22T17:43:35.150Z https://longevityharbor.com/de/watch/0IIAWa5GZC4 Epigenetic Clocks for Testing Your Biological Age https://i.ytimg.com/vi/0IIAWa5GZC4/hqdefault.jpg Epigenetic clocks have become established as robust measures of chronological age, surpassing telomere length as the best age predictor. In addition to predicting time-to-death, epigenetic clocks also appear to foretell healthspan indicators, such as cognitive decline, frailty, arthritis, and the progression of diseases like Alzheimer’s and Parkinson’s. What are telomeres? See What to Eat to Prevent Telomere Shortening (https://nutritionfacts.org/video/what-to-eat-to-prevent-telomere-shortening/). For more on epigenetics and disease, see my videos The Role of Epigenetics in the Obesity Epidemic (https://nutritionfacts.org/video/the-role-of-epigenetics-in-the-obesity-epidemic/) and Animal Protein, Pregnancy, and Childhood Obesity (https://nutritionfacts.org/video/animal-protein-pregnancy-and-childhood-obesity/). For more on how to slow biological aging, check out my book How Not to Age (https://nutritionfacts.org/book/how-not-to-age/) from your local public library. If you haven’t seen them yet, check out the book trailer (https://nutritionfacts.org/video/book-trailer-for-how-not-to-age) and my new presentation (https://nutritionfacts.org/video/how-not-to-age-live-presentation/). (As always, all proceeds I receive from all of my books (https://nutritionfacts.org/books/) are donated to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/epigenetic-clocks-for-testing-your-biological-age and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/epigenetic-clocks-for-testing-your-biological-age. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 h https://www.youtube-nocookie.com/embed/0IIAWa5GZC4 357 2024-08-28T11:59:52.000Z 2026-10-22T17:43:35.150Z https://longevityharbor.com/en/watch/0KfNVUV6M0U Video description: six daily habits proposed for healthy aging after 55 https://i.ytimg.com/vi/0KfNVUV6M0U/hqdefault.jpg The description says Dr. Cale Smith presents six habits for adults over 55: movement, strength training, anti-inflammatory nutrition, brain health, social connection and sleep. It names no study results. https://www.youtube-nocookie.com/embed/0KfNVUV6M0U 1513 2026-10-01T17:44:57.000Z 2026-10-22T21:31:59.826Z https://longevityharbor.com/de/watch/0KfNVUV6M0U Videobeschreibung: sechs Alltagsgewohnheiten für gesundes Altern ab 55 https://i.ytimg.com/vi/0KfNVUV6M0U/hqdefault.jpg Laut Beschreibung stellt Dr. Cale Smith sechs Gewohnheiten für Erwachsene über 55 vor: Bewegung, Krafttraining, entzündungshemmende Ernährung, Gehirngesundheit, soziale Kontakte und Schlaf. Studienergebnisse werden nicht genannt. https://www.youtube-nocookie.com/embed/0KfNVUV6M0U 1513 2026-10-01T17:44:57.000Z 2026-10-22T21:31:59.826Z https://longevityharbor.com/en/watch/0Ld4Jzi3nSs Podcast: Is aging a disease? Weinkove on longevity and healthspan https://i.ytimg.com/vi/0Ld4Jzi3nSs/hqdefault.jpg In this Brighter100 episode description, Professor David Weinkove argues aging is likely not a disease itself, though it is described as one of the strongest risk factors for chronic conditions, and that no single pill is likely to solve aging. https://www.youtube-nocookie.com/embed/0Ld4Jzi3nSs 3493 2026-07-26T12:14:51.000Z 2026-10-22T23:22:30.249Z https://longevityharbor.com/de/watch/0Ld4Jzi3nSs Podcast: Ist Altern eine Krankheit? Weinkove über Langlebigkeit und Gesundheitsspanne https://i.ytimg.com/vi/0Ld4Jzi3nSs/hqdefault.jpg In dieser Beschreibung einer Brighter100-Episode argumentiert Professor David Weinkove, Altern sei wahrscheinlich keine Krankheit an sich, werde aber als einer der stärksten Risikofaktoren für chronische Erkrankungen beschrieben; eine einzelne Pille werde das Altern wohl nicht lösen. https://www.youtube-nocookie.com/embed/0Ld4Jzi3nSs 3493 2026-07-26T12:14:51.000Z 2026-10-22T23:22:30.249Z https://longevityharbor.com/en/watch/0M4G9MZTcjk Death, Grief, & Purpose from a Longevity Science Perspective https://i.ytimg.com/vi/0M4G9MZTcjk/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Grief: one of the most profound emotions humanity shares; a universal experience that transcends time, culture, and place; a phenomenon as ancient as human existence. Grief is as intrinsic to the human experience as joy or hope, and no one escapes it—to grieve is to be human. In this episode, Matt and Nick discuss their recent personal experiences with grief and loss. Matt lost his German Shepherd Dobby to degenerative myelopathy, while Nick's father succumbed to health issues precipitated by heavy alcohol use. Together they explore how grief affects mental and physical health, including how it affects the four Pillars of Healthspan—Eat, Sleep, Move, and Connect—as well as the hallmarks of aging. They also discuss the tricky emotions that can accompany grief, the different ways people react to change, and the unanticipated positives of negative experiences. 0:00 Introduction 4:11 Reacting to grief differently 7:20 Dealing with change 9:56 How Nick handled his first major loss 16:21 Grieving things other than loved ones 18:36 The five stages of grief 19:55 How grief affected the Pillars of Health for Matt and Nick 29:30 Grief and the hallmarks of aging 35:50 Takeaways for dealing with grief 41:24 Death and the longevity field 45:18 Deriving purpose from life 48:10 Closing thoughts Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided b https://www.youtube-nocookie.com/embed/0M4G9MZTcjk 2953 2024-11-14T14:00:01.000Z 2026-10-22T19:54:20.467Z https://longevityharbor.com/de/watch/0M4G9MZTcjk Death, Grief, & Purpose from a Longevity Science Perspective https://i.ytimg.com/vi/0M4G9MZTcjk/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Grief: one of the most profound emotions humanity shares; a universal experience that transcends time, culture, and place; a phenomenon as ancient as human existence. Grief is as intrinsic to the human experience as joy or hope, and no one escapes it—to grieve is to be human. In this episode, Matt and Nick discuss their recent personal experiences with grief and loss. Matt lost his German Shepherd Dobby to degenerative myelopathy, while Nick's father succumbed to health issues precipitated by heavy alcohol use. Together they explore how grief affects mental and physical health, including how it affects the four Pillars of Healthspan—Eat, Sleep, Move, and Connect—as well as the hallmarks of aging. They also discuss the tricky emotions that can accompany grief, the different ways people react to change, and the unanticipated positives of negative experiences. 0:00 Introduction 4:11 Reacting to grief differently 7:20 Dealing with change 9:56 How Nick handled his first major loss 16:21 Grieving things other than loved ones 18:36 The five stages of grief 19:55 How grief affected the Pillars of Health for Matt and Nick 29:30 Grief and the hallmarks of aging 35:50 Takeaways for dealing with grief 41:24 Death and the longevity field 45:18 Deriving purpose from life 48:10 Closing thoughts Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided b https://www.youtube-nocookie.com/embed/0M4G9MZTcjk 2953 2024-11-14T14:00:01.000Z 2026-10-22T19:54:20.467Z https://longevityharbor.com/en/watch/0M6iG_0IJSM Your brain has a ⏰. Disrupt your circadian rhythm long-term and dementia risk increases. https://i.ytimg.com/vi/0M6iG_0IJSM/hqdefault.jpg Your brain has a ⏰. Disrupt your circadian rhythm long-term and dementia risk increases. https://www.youtube-nocookie.com/embed/0M6iG_0IJSM 113 2026-02-19T14:58:22.000Z 2026-10-22T18:54:02.122Z https://longevityharbor.com/de/watch/0M6iG_0IJSM Your brain has a ⏰. Disrupt your circadian rhythm long-term and dementia risk increases. https://i.ytimg.com/vi/0M6iG_0IJSM/hqdefault.jpg Your brain has a ⏰. Disrupt your circadian rhythm long-term and dementia risk increases. https://www.youtube-nocookie.com/embed/0M6iG_0IJSM 113 2026-02-19T14:58:22.000Z 2026-10-22T18:54:02.122Z https://longevityharbor.com/en/watch/0Qt1pizYdKA NAD+ in the video description: cellular energy and aging claims https://i.ytimg.com/vi/0Qt1pizYdKA/hqdefault.jpg A video description says NAD+ helps cells turn nutrients into energy and that NAD+ levels tend to decline with age, which is why it draws interest for cellular energy and healthy aging. No study, data or outcomes are reported. https://www.youtube-nocookie.com/embed/0Qt1pizYdKA 125 2026-10-16T12:30:36.000Z 2026-10-22T19:52:18.894Z https://longevityharbor.com/de/watch/0Qt1pizYdKA NAD+ in der Videobeschreibung: Aussagen zu Zellenergie und Altern https://i.ytimg.com/vi/0Qt1pizYdKA/hqdefault.jpg Eine Videobeschreibung sagt, NAD+ helfe Zellen, Nährstoffe in Energie umzuwandeln, und NAD+-Spiegel sinken mit dem Alter tendenziell, weshalb es für Zellenergie und gesundes Altern interessant sei. Es werden keine Studie, Daten oder Ergebnisse berichtet. https://www.youtube-nocookie.com/embed/0Qt1pizYdKA 125 2026-10-16T12:30:36.000Z 2026-10-22T19:52:18.894Z https://longevityharbor.com/en/watch/0QyQY9ToQpw Biohacking Aging: Everything You Need To Know About Rapamycin https://i.ytimg.com/vi/0QyQY9ToQpw/hqdefault.jpg Rapamycin might be the most powerful longevity drug ever discovered — a molecule that slows aging by tricking your cells into thinking they’re fasting. In this video, I break down how rapamycin actually works, what the ITP studies found, and why it’s one of the only drugs that consistently extends lifespan in mammals. We’ll look at the human trials, side effects, and mechanism of action. Connect with Me: Subscribe to this channel: https://www.youtube.com/@DarkModeBiohacking?sub_confirmation=1 Discord: https://discord.gg/4WH9bxv2 X: https://x.com/darkmodebio Chapters: 00:00 Intro 00:39 1 – Why Did Nature Make This? 01:24 2 – How Does it Work? 02:42 3 – What Do the Studies Say? References: Rapamycin, the only drug that has been consistently demonstrated to increase mammalian longevity. An update 10.1016/j.exger.2023.112166 Rapamycin for longevity: the pros, the cons, and future perspectives 10.3389/fragi.2025.1628187 What is the clinical evidence to support off-label rapamycin therapy in healthy adults? 10.18632/aging.206300 Sirolimus and mTOR Inhibitors: A Review of Side Effects and Specific Management in Solid Organ Transplantation 10.1007/s40264-019-00810-9 Targeting the biology of ageing with mTOR inhibitors to improve immune function in older adults: phase 2b and phase 3 randomised trials 10.1016/s2666-7568(21)00062-3 Hallmarks of aging: An expanding universe 10.1016/j.cell.2022.11.001 Targeting ageing with rapamycin and its derivatives in humans: a systematic review 10.1016/s2666-7568(23)00258-1 Blazing a trail for the clinical use of rapamycin as a geroprotecTOR 10.1007/s11357-023-00935-x Evaluation of off-label rapamycin use to promote healthspan in 333 adults 10.1007/s11357-023-00818-1 Sex as a major determinant of pro-longevity drug efficacy: a review of two decades of the NIA Interventions Testing Program 10.1093/gerona/glaf138 Rapamycin, Not Metformin, Mirrors Dietary Restriction‐Driven Lifespan Extension in Vertebrates: A Meta‐Analysis https://www.youtube-nocookie.com/embed/0QyQY9ToQpw 283 2025-10-30T01:49:52.000Z 2026-10-22T17:43:41.088Z https://longevityharbor.com/de/watch/0QyQY9ToQpw Biohacking Aging: Everything You Need To Know About Rapamycin https://i.ytimg.com/vi/0QyQY9ToQpw/hqdefault.jpg Rapamycin might be the most powerful longevity drug ever discovered — a molecule that slows aging by tricking your cells into thinking they’re fasting. In this video, I break down how rapamycin actually works, what the ITP studies found, and why it’s one of the only drugs that consistently extends lifespan in mammals. We’ll look at the human trials, side effects, and mechanism of action. Connect with Me: Subscribe to this channel: https://www.youtube.com/@DarkModeBiohacking?sub_confirmation=1 Discord: https://discord.gg/4WH9bxv2 X: https://x.com/darkmodebio Chapters: 00:00 Intro 00:39 1 – Why Did Nature Make This? 01:24 2 – How Does it Work? 02:42 3 – What Do the Studies Say? References: Rapamycin, the only drug that has been consistently demonstrated to increase mammalian longevity. An update 10.1016/j.exger.2023.112166 Rapamycin for longevity: the pros, the cons, and future perspectives 10.3389/fragi.2025.1628187 What is the clinical evidence to support off-label rapamycin therapy in healthy adults? 10.18632/aging.206300 Sirolimus and mTOR Inhibitors: A Review of Side Effects and Specific Management in Solid Organ Transplantation 10.1007/s40264-019-00810-9 Targeting the biology of ageing with mTOR inhibitors to improve immune function in older adults: phase 2b and phase 3 randomised trials 10.1016/s2666-7568(21)00062-3 Hallmarks of aging: An expanding universe 10.1016/j.cell.2022.11.001 Targeting ageing with rapamycin and its derivatives in humans: a systematic review 10.1016/s2666-7568(23)00258-1 Blazing a trail for the clinical use of rapamycin as a geroprotecTOR 10.1007/s11357-023-00935-x Evaluation of off-label rapamycin use to promote healthspan in 333 adults 10.1007/s11357-023-00818-1 Sex as a major determinant of pro-longevity drug efficacy: a review of two decades of the NIA Interventions Testing Program 10.1093/gerona/glaf138 Rapamycin, Not Metformin, Mirrors Dietary Restriction‐Driven Lifespan Extension in Vertebrates: A Meta‐Analysis https://www.youtube-nocookie.com/embed/0QyQY9ToQpw 283 2025-10-30T01:49:52.000Z 2026-10-22T17:43:41.088Z https://longevityharbor.com/en/watch/0Yv_e2KYG0Q Warum Muskelkraft über Ihre Gesundheit entscheidet | Dr. Simone Koch https://i.ytimg.com/vi/0Yv_e2KYG0Q/hqdefault.jpg Muskeln sind weit mehr als nur Kraft – sie wirken wie ein hormonaktives Organ, regulieren den Stoffwechsel und schützen vor Entzündungen. Dr. Simone Koch erklärt im ERCM Medizin Podcast, warum gezieltes Training die Grundlage für Gesundheit, Energie und Langlebigkeit ist. Darüber spricht sie: - Warum Muskeln das wichtigste Organ für Ihre Gesundheit sind - Wie Myokine Entzündungen im Körper hemmen - Warum Muskeltraining Krankheiten vorbeugt und den Stoffwechsel stärkt - Welche Rolle Bewegung für gesundes Altern spielt 📺 Sehen Sie sich die ganze Folge hier an: https://youtu.be/qAop6GeYF2M Abonnieren Sie unseren Hauptkanal: @ERCMPodcast #Muskeln #Gesundheit #Langlebigkeit #Myokine #Krafttraining #Prävention #GesundAltern #ercmpodcast https://www.youtube-nocookie.com/embed/0Yv_e2KYG0Q 368 2025-10-08T14:30:01.000Z 2026-10-22T18:54:05.055Z https://longevityharbor.com/de/watch/0Yv_e2KYG0Q Warum Muskelkraft über Ihre Gesundheit entscheidet | Dr. Simone Koch https://i.ytimg.com/vi/0Yv_e2KYG0Q/hqdefault.jpg Muskeln sind weit mehr als nur Kraft – sie wirken wie ein hormonaktives Organ, regulieren den Stoffwechsel und schützen vor Entzündungen. Dr. Simone Koch erklärt im ERCM Medizin Podcast, warum gezieltes Training die Grundlage für Gesundheit, Energie und Langlebigkeit ist. Darüber spricht sie: - Warum Muskeln das wichtigste Organ für Ihre Gesundheit sind - Wie Myokine Entzündungen im Körper hemmen - Warum Muskeltraining Krankheiten vorbeugt und den Stoffwechsel stärkt - Welche Rolle Bewegung für gesundes Altern spielt 📺 Sehen Sie sich die ganze Folge hier an: https://youtu.be/qAop6GeYF2M Abonnieren Sie unseren Hauptkanal: @ERCMPodcast #Muskeln #Gesundheit #Langlebigkeit #Myokine #Krafttraining #Prävention #GesundAltern #ercmpodcast https://www.youtube-nocookie.com/embed/0Yv_e2KYG0Q 368 2025-10-08T14:30:01.000Z 2026-10-22T18:54:05.055Z https://longevityharbor.com/en/watch/0aHOSFOLE8A Video description: eggs, leucine and protein timing for muscle loss after 50 https://i.ytimg.com/vi/0aHOSFOLE8A/hqdefault.jpg This video description claims bone broth barely helps rebuild muscle, while eggs, the amino acid leucine and spreading protein across the day may counter muscle loss after 50. No studies, numbers or outcomes are reported; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/0aHOSFOLE8A 1364 2026-10-19T22:23:44.000Z 2026-10-22T19:49:59.333Z https://longevityharbor.com/de/watch/0aHOSFOLE8A Videobeschreibung: Eier, Leucin und Protein-Timing bei Muskelverlust nach 50 https://i.ytimg.com/vi/0aHOSFOLE8A/hqdefault.jpg Diese Videobeschreibung behauptet, Knochenbrühe helfe kaum beim Muskelaufbau, während Eier, die Aminosäure Leucin und über den Tag verteiltes Protein dem Muskelverlust nach 50 entgegenwirken könnten. Es werden keine Studien, Zahlen oder Ergebnisse genannt; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/0aHOSFOLE8A 1364 2026-10-19T22:23:44.000Z 2026-10-22T19:49:59.333Z https://longevityharbor.com/en/watch/0gMea70xodw Video description: leg weakness after 60 linked to motor unit loss, not only muscle shrinkage https://i.ytimg.com/vi/0gMea70xodw/hqdefault.jpg The description says new research points beyond shrinking muscles: by the 70s, up to a third of nerve connections controlling leg muscles may be gone, and this motor unit loss is presented as a bigger reason for weak legs after 60. https://www.youtube-nocookie.com/embed/0gMea70xodw 1227 2026-08-19T16:00:19.000Z 2026-10-22T22:54:26.175Z https://longevityharbor.com/de/watch/0gMea70xodw Videobeschreibung: Beinschwäche nach 60 mit Verlust motorischer Einheiten, nicht nur Muskelschwund https://i.ytimg.com/vi/0gMea70xodw/hqdefault.jpg Laut Beschreibung deutet neue Forschung über Muskelschwund hinaus: Bis in die 70er könne bis zu ein Drittel der Nervenverbindungen zu den Beinmuskeln fehlen; dieser Verlust motorischer Einheiten wird als wichtigerer Grund für schwache Beine nach 60 dargestellt. https://www.youtube-nocookie.com/embed/0gMea70xodw 1227 2026-08-19T16:00:19.000Z 2026-10-22T22:54:26.175Z https://longevityharbor.com/en/watch/0iQsi8jdAjg Video description lists 13 habits for aging after 40, not tested anti-aging methods https://i.ytimg.com/vi/0iQsi8jdAjg/hqdefault.jpg The description of this video lists 13 science-backed ways to reverse aging after 40, with chapters on sleep, movement, breakfast, blood sugar, diet, inflammation and gut health. It gives no study details, results or evidence, and the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/0iQsi8jdAjg 801 2026-10-02T14:45:32.000Z 2026-10-22T21:30:33.984Z https://longevityharbor.com/de/watch/0iQsi8jdAjg Videobeschreibung nennt 13 Gewohnheiten ab 40, keine geprüften Anti-Aging-Methoden https://i.ytimg.com/vi/0iQsi8jdAjg/hqdefault.jpg Die Beschreibung dieses Videos nennt 13 wissenschaftlich untermauerte Wege, das Altern nach 40 rückwärts zu drehen, mit Kapiteln zu Schlaf, Bewegung, Frühstück, Blutzucker, Ernährung, Entzündung und Darmgesundheit. Sie liefert keine Studiendetails, Ergebnisse oder Belege; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/0iQsi8jdAjg 801 2026-10-02T14:45:32.000Z 2026-10-22T21:30:33.984Z https://longevityharbor.com/en/watch/0nvd9_8OYhE Quercetin and senolytics: a video description on clearing senescent cells https://i.ytimg.com/vi/0nvd9_8OYhE/hqdefault.jpg The description presents quercetin as a plant flavonoid that, according to the creator, acts as an antioxidant and anti-inflammatory and helps the body identify and eliminate senescent 'zombie cells'. It also mentions food sources such as red onions and kale and concentrated supplements; no study results are given. https://www.youtube-nocookie.com/embed/0nvd9_8OYhE 117 2026-03-09T16:31:36.000Z 2026-10-23T02:11:47.421Z https://longevityharbor.com/de/watch/0nvd9_8OYhE Quercetin und Senolytika: eine Videobeschreibung zum Entfernen seneszenter Zellen https://i.ytimg.com/vi/0nvd9_8OYhE/hqdefault.jpg Die Beschreibung stellt Quercetin als pflanzliches Flavonoid dar, das laut dem Ersteller als Antioxidans und entzündungshemmend wirkt und dem Körper helfen soll, seneszente „Zombie-Zellen“ zu erkennen und zu entfernen. Außerdem nennt sie Lebensmittelquellen wie rote Zwiebeln und Grünkohl sowie konzentrierte Nahrungsergänzungsmittel; Studienergebnisse werden nicht genannt. https://www.youtube-nocookie.com/embed/0nvd9_8OYhE 117 2026-03-09T16:31:36.000Z 2026-10-23T02:11:47.421Z https://longevityharbor.com/en/watch/0okQz-3XM_w Video description: strength training and healthy ageing, with muscles as more than appearance https://i.ytimg.com/vi/0okQz-3XM_w/hqdefault.jpg The description presents regular strength training as one of the most important measures for healthy ageing and says muscles affect balance, metabolism, mobility and quality of life. It attributes these points to the creator and cites studies, but gives no study details. https://www.youtube-nocookie.com/embed/0okQz-3XM_w 614 2026-04-25T07:00:01.000Z 2026-10-23T01:24:07.943Z https://longevityharbor.com/de/watch/0okQz-3XM_w Videobeschreibung: Krafttraining und gesundes Altern – Muskeln sind mehr als Optik https://i.ytimg.com/vi/0okQz-3XM_w/hqdefault.jpg Die Beschreibung stellt regelmäßiges Krafttraining als eine der wichtigsten Maßnahmen für gesundes Altern dar und nennt Auswirkungen von Muskeln auf Gleichgewicht, Stoffwechsel, Mobilität und Lebensqualität. Sie schreibt dies dem Ersteller zu und verweist auf Studien, ohne Studiendetails zu nennen. https://www.youtube-nocookie.com/embed/0okQz-3XM_w 614 2026-04-25T07:00:01.000Z 2026-10-23T01:24:07.943Z https://longevityharbor.com/en/watch/0vn793tn3Dc Vivix+ video description: NMN, NAD⁺ and Shaklee trial claims https://i.ytimg.com/vi/0vn793tn3Dc/hqdefault.jpg The description says the video explains Vivix+ ingredients, what NAD⁺ does and why it declines with age, Shaklee trial results on VO2 max, inflammation and DNA damage, and how the supplement compares with NAD⁺ IV drips. https://www.youtube-nocookie.com/embed/0vn793tn3Dc 333 2026-08-23T20:48:20.000Z 2026-10-22T22:48:25.342Z https://longevityharbor.com/de/watch/0vn793tn3Dc Vivix+-Videobeschreibung: NMN, NAD⁺ und Shaklee-Studienangaben https://i.ytimg.com/vi/0vn793tn3Dc/hqdefault.jpg Laut Beschreibung erklärt das Video die Inhaltsstoffe von Vivix+, was NAD⁺ in Zellen tut und warum es mit dem Alter abnimmt, Shaklee-Studienergebnisse zu VO2 max, Entzündung und DNA-Schäden sowie den Vergleich mit NAD⁺-Infusionen. https://www.youtube-nocookie.com/embed/0vn793tn3Dc 333 2026-08-23T20:48:20.000Z 2026-10-22T22:48:25.342Z https://longevityharbor.com/en/watch/0zaCKAnFogQ The epigenetic clock, biological age, and chronic diseases https://i.ytimg.com/vi/0zaCKAnFogQ/hqdefault.jpg The epigenetic clock, biological age, and chronic diseases Air date: Wednesday, June 15, 2016, 3:00:00 PM Category: WALS - Wednesday Afternoon Lectures Runtime: 01:03:40 Description: NIH Director’s Wednesday Afternoon Lecture Series It has been a long standing goal to develop molecular biomarkers of biological age. Recent studies demonstrate that powerful epigenetic biomarkers of aging can be defined based on DNA methylation levels. For example, the epigenetic clock (PMID: 24138928) is a multivariate age estimation method that applies to sorted cell types (CD4T cells or neurons), complex tissues, and organs and even prenatal brain samples. The epigenetic clock is an attractive biomarker of aging because a) it applies to most human and chimpanzee tissues, b) its accurate measurement of chronological age is unprecedented, c) it is predictive of all-cause mortality even after adjusting for a variety of known risk factors, d) it correlates with measures of cognitive and physical fitness in the elderly, and e) it has been found useful for detecting accelerated aging effects due to obesity, Down syndrome, and HIV infection. Recent genomewide association studies shed light on the underlying biological mechanisms. For more information go to https://oir.nih.gov/wals Author: Steve Horvath, Sc.D., Ph.D., University of California, Los Angeles Permanent link: http://videocast.nih.gov/launch.asp?19753 https://www.youtube-nocookie.com/embed/0zaCKAnFogQ 3820 2016-06-20T15:29:19.000Z 2026-10-22T17:11:30.670Z https://longevityharbor.com/de/watch/0zaCKAnFogQ The epigenetic clock, biological age, and chronic diseases https://i.ytimg.com/vi/0zaCKAnFogQ/hqdefault.jpg The epigenetic clock, biological age, and chronic diseases Air date: Wednesday, June 15, 2016, 3:00:00 PM Category: WALS - Wednesday Afternoon Lectures Runtime: 01:03:40 Description: NIH Director’s Wednesday Afternoon Lecture Series It has been a long standing goal to develop molecular biomarkers of biological age. Recent studies demonstrate that powerful epigenetic biomarkers of aging can be defined based on DNA methylation levels. For example, the epigenetic clock (PMID: 24138928) is a multivariate age estimation method that applies to sorted cell types (CD4T cells or neurons), complex tissues, and organs and even prenatal brain samples. The epigenetic clock is an attractive biomarker of aging because a) it applies to most human and chimpanzee tissues, b) its accurate measurement of chronological age is unprecedented, c) it is predictive of all-cause mortality even after adjusting for a variety of known risk factors, d) it correlates with measures of cognitive and physical fitness in the elderly, and e) it has been found useful for detecting accelerated aging effects due to obesity, Down syndrome, and HIV infection. Recent genomewide association studies shed light on the underlying biological mechanisms. For more information go to https://oir.nih.gov/wals Author: Steve Horvath, Sc.D., Ph.D., University of California, Los Angeles Permanent link: http://videocast.nih.gov/launch.asp?19753 https://www.youtube-nocookie.com/embed/0zaCKAnFogQ 3820 2016-06-20T15:29:19.000Z 2026-10-22T17:11:30.670Z https://longevityharbor.com/en/watch/0znPGtxF8cU Video description: caloric restriction and intermittent fasting as autophagy triggers after 60 https://i.ytimg.com/vi/0znPGtxF8cU/hqdefault.jpg The description says Dr. Thomas explains caloric restriction and intermittent fasting as autophagy triggers, cites the CALERIE trial and animal lifespan findings, and names risks; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/0znPGtxF8cU 469 2026-04-16T18:00:06.000Z 2026-10-23T01:34:13.968Z https://longevityharbor.com/de/watch/0znPGtxF8cU Videobeschreibung: Kalorienrestriktion und Intervallfasten als Autophagie-Auslöser nach 60 https://i.ytimg.com/vi/0znPGtxF8cU/hqdefault.jpg Laut Beschreibung erklärt Dr. Thomas Kalorienrestriktion und Intervallfasten als Autophagie-Auslöser, nennt die CALERIE-Studie und Tierbefunde zur Lebensspanne sowie Risiken; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/0znPGtxF8cU 469 2026-04-16T18:00:06.000Z 2026-10-23T01:34:13.968Z https://longevityharbor.com/en/watch/11-N3QHs4n8 Video description: epigenetic clock, DNA methylation and lifestyle factors https://i.ytimg.com/vi/11-N3QHs4n8/hqdefault.jpg The description presents the epigenetic clock as a biomarker that tracks chemical DNA modifications and distinguishes biological from chronological age; it says diet, sleep, movement and stress can influence this clock, without reporting results. https://www.youtube-nocookie.com/embed/11-N3QHs4n8 487 2026-03-13T03:00:01.000Z 2026-10-23T02:09:32.490Z https://longevityharbor.com/de/watch/11-N3QHs4n8 Videobeschreibung: epigenetische Uhr, DNA-Methylierung und Lebensstilfaktoren https://i.ytimg.com/vi/11-N3QHs4n8/hqdefault.jpg Die Beschreibung stellt die epigenetische Uhr als Biomarker vor, der chemische DNA-Veränderungen erfasst und biologisches von chronologischem Alter unterscheidet; Ernährung, Schlaf, Bewegung und Stress könnten diese Uhr beeinflussen, Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/11-N3QHs4n8 487 2026-03-13T03:00:01.000Z 2026-10-23T02:09:32.490Z https://longevityharbor.com/en/watch/132HfSBXuBk Doctor Reviews NAD+ vs Peptides - Which Does MORE? https://i.ytimg.com/vi/132HfSBXuBk/hqdefault.jpg In this video, I break down two of the buzziest topics in wellness right now—NAD+ therapy and peptides—and give you a clear, no-nonsense comparison from a real primary care doctor. What you’ll learn in this video: What NAD+ is, how it fuels your mitochondria, and why you might need more of it as you age What peptides are, the most common ones being used (BPC-157, CJC-1295, ipamorelin, etc.), and what they claim to do The truth about cost, safety, and clinical evidence My honest take as a doctor on whether NAD or peptides are worth your money I’ll cover benefits, risks, sourcing issues, and real-world stories so you can decide which—if any—makes sense for your goals. ***Nothing I share here is personal medical advice. Always check with your own provider before starting a new supplement or treatment.*** my preferred brand (this is an affiliate link and I earn a small comission from purchases made through this link): https://bit.ly/45DOjXF Get a FREE Peptide Roadmap https://peptideroadmap.drafroese.com https://www.youtube-nocookie.com/embed/132HfSBXuBk 416 2025-09-09T12:00:04.000Z 2026-10-22T19:32:38.584Z https://longevityharbor.com/de/watch/132HfSBXuBk Doctor Reviews NAD+ vs Peptides - Which Does MORE? https://i.ytimg.com/vi/132HfSBXuBk/hqdefault.jpg In this video, I break down two of the buzziest topics in wellness right now—NAD+ therapy and peptides—and give you a clear, no-nonsense comparison from a real primary care doctor. What you’ll learn in this video: What NAD+ is, how it fuels your mitochondria, and why you might need more of it as you age What peptides are, the most common ones being used (BPC-157, CJC-1295, ipamorelin, etc.), and what they claim to do The truth about cost, safety, and clinical evidence My honest take as a doctor on whether NAD or peptides are worth your money I’ll cover benefits, risks, sourcing issues, and real-world stories so you can decide which—if any—makes sense for your goals. ***Nothing I share here is personal medical advice. Always check with your own provider before starting a new supplement or treatment.*** my preferred brand (this is an affiliate link and I earn a small comission from purchases made through this link): https://bit.ly/45DOjXF Get a FREE Peptide Roadmap https://peptideroadmap.drafroese.com https://www.youtube-nocookie.com/embed/132HfSBXuBk 416 2025-09-09T12:00:04.000Z 2026-10-22T19:32:38.584Z https://longevityharbor.com/en/watch/16U3G3GbVWk Conference talk: nutraceuticals and cellular senescence, animal and human findings https://i.ytimg.com/vi/16U3G3GbVWk/hqdefault.jpg In this conference description, Dr Lihuan Guan is said to examine nutraceutical effects on cellular senescence, drawing on animal models and human studies. The description gives no results, numbers or study designs. https://www.youtube-nocookie.com/embed/16U3G3GbVWk 361 2026-08-26T06:29:29.000Z 2026-10-22T22:42:42.241Z https://longevityharbor.com/de/watch/16U3G3GbVWk Konferenzvortrag: Nutrazeutika und zelluläre Seneszenz, Tier- und Humanbefunde https://i.ytimg.com/vi/16U3G3GbVWk/hqdefault.jpg In dieser Konferenzbeschreibung wird Dr. Lihuan Guan vorgestellt, die Effekte von Nutrazeutika auf zelluläre Seneszenz anhand von Tiermodellen und Humanstudien untersucht. Ergebnisse, Zahlen oder Studiendesigns nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/16U3G3GbVWk 361 2026-08-26T06:29:29.000Z 2026-10-22T22:42:42.241Z https://longevityharbor.com/en/watch/16xlLK_Zsus Video describes DEAF1–mTORC1 muscle-aging pathway in flies and mice https://i.ytimg.com/vi/16xlLK_Zsus/hqdefault.jpg The description presents a peer-reviewed study in fruit flies and aged mice linking exercise to lower DEAF1 and normalized mTORC1 activity; human trials are described as the next step. https://www.youtube-nocookie.com/embed/16xlLK_Zsus 621 2026-08-25T16:00:08.000Z 2026-10-22T22:46:47.227Z https://longevityharbor.com/de/watch/16xlLK_Zsus Video beschreibt DEAF1-mTORC1-Muskelalterung bei Fliegen und Mäusen https://i.ytimg.com/vi/16xlLK_Zsus/hqdefault.jpg Die Beschreibung stellt eine begutachtete Studie an Fruchtfliegen und gealterten Mäusen vor, die Training mit weniger DEAF1 und normalisierter mTORC1-Aktivität verbindet; Humanstudien werden als nächster Schritt genannt. https://www.youtube-nocookie.com/embed/16xlLK_Zsus 621 2026-08-25T16:00:08.000Z 2026-10-22T22:46:47.227Z https://longevityharbor.com/en/watch/1C0gudubTgg Calorie restriction vs fasting: what the video description says https://i.ytimg.com/vi/1C0gudubTgg/hqdefault.jpg The description says both calorie restriction and fasting can influence longevity-linked biomarkers, but timing, intensity and individual response differ; it reports no study results. https://www.youtube-nocookie.com/embed/1C0gudubTgg 99 2026-05-18T17:00:02.000Z 2026-10-23T00:44:46.290Z https://longevityharbor.com/de/watch/1C0gudubTgg Kalorienrestriktion vs. Fasten: Was die Videobeschreibung sagt https://i.ytimg.com/vi/1C0gudubTgg/hqdefault.jpg Die Beschreibung sagt, dass Kalorienrestriktion und Fasten beide altersbezogene Biomarker beeinflussen können, doch Zeitpunkt, Intensität und individuelle Reaktion unterscheiden sich; Studienergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/1C0gudubTgg 99 2026-05-18T17:00:02.000Z 2026-10-23T00:44:46.290Z https://longevityharbor.com/en/watch/1D5LGsQw538 6mg of rapamycin per week, is it a safe dose for longevity? https://i.ytimg.com/vi/1D5LGsQw538/hqdefault.jpg In this episode of TimePie on site, we are glad to welcome Professor Andrea Maier to share with us his opinion on the following four questions regarding antiaging and longevity: 1. You have conducted extensive research on muscle health and nutrition in the elderly. In your opinion, what diet/nutrition intervention do you think is best for preventing muscle loss in the elderly, and are there any other recommended interventions? 2. You have shared on ARDD two impressive clinical trials: one using an age clock to screen subjects to enter the AKG trial, and another involving healthy adults taking 6 mg of rapamycin per day. What is the progress of the trials so far? 3. Some readers have expressed concern that 6 mg per day may be too high. What is your opinion? 4. What is the current operational status and recruitment progress of the first longevity clinic in Singapore since its opening, and are there any plans to expand its scale? Professor Maier serves at the National University of Singapore as Co-Director of the Centre for Healthy Longevity as well as the President of the Australian and New Zealand Society for Sarcopenia and Frailty Research. Her research focuses on unraveling the mechanisms of ageing and age-related diseases. During the last 10 years she has conducted multiple international observational studies and intervention trials and has published more than 300 peer-reviewed articles, achieving an H index of 54. #aging #longevity #antiaging #rapamycin #akg #drug #lifespan https://www.youtube-nocookie.com/embed/1D5LGsQw538 230 2024-04-06T16:00:01.000Z 2026-10-22T19:54:22.284Z https://longevityharbor.com/de/watch/1D5LGsQw538 6mg of rapamycin per week, is it a safe dose for longevity? https://i.ytimg.com/vi/1D5LGsQw538/hqdefault.jpg In this episode of TimePie on site, we are glad to welcome Professor Andrea Maier to share with us his opinion on the following four questions regarding antiaging and longevity: 1. You have conducted extensive research on muscle health and nutrition in the elderly. In your opinion, what diet/nutrition intervention do you think is best for preventing muscle loss in the elderly, and are there any other recommended interventions? 2. You have shared on ARDD two impressive clinical trials: one using an age clock to screen subjects to enter the AKG trial, and another involving healthy adults taking 6 mg of rapamycin per day. What is the progress of the trials so far? 3. Some readers have expressed concern that 6 mg per day may be too high. What is your opinion? 4. What is the current operational status and recruitment progress of the first longevity clinic in Singapore since its opening, and are there any plans to expand its scale? Professor Maier serves at the National University of Singapore as Co-Director of the Centre for Healthy Longevity as well as the President of the Australian and New Zealand Society for Sarcopenia and Frailty Research. Her research focuses on unraveling the mechanisms of ageing and age-related diseases. During the last 10 years she has conducted multiple international observational studies and intervention trials and has published more than 300 peer-reviewed articles, achieving an H index of 54. #aging #longevity #antiaging #rapamycin #akg #drug #lifespan https://www.youtube-nocookie.com/embed/1D5LGsQw538 230 2024-04-06T16:00:01.000Z 2026-10-22T19:54:22.284Z https://longevityharbor.com/en/watch/1NlWfFH0Bhs DEREGULATED NUTRIENT SENSING & AGING | The Hallmarks of Aging [2020] https://i.ytimg.com/vi/1NlWfFH0Bhs/hqdefault.jpg DEREGULATED NUTRIENT SENSING & AGING. Today we’ll be covering one of the Hallmarks of Aging, and if you use research into drugs that can extend the human lifespan, one of the most important ones. Food is essential. We eat food to fuel our bodies so we can move and to repair and build tissues. In order for our bodies to use food as fuel, it has to recognize the nutrients and get to work breaking them down and utilizing them. Good thing our bodies have several mechanisms to make that happen. This is the latest installment on the series on The Hallmarks Of Aging. In today's video, we will go over nutrient-sensing, which pathways are involved in that and how those processes tend to change, or become deregulated, as we age. And as always, there will be discussion to go over what, if anything, can be done about reversing those changes. Tune in to learn more about how the body uses food as fuel and how that changes as we age. https://www.youtube-nocookie.com/embed/1NlWfFH0Bhs 562 2020-08-18T19:47:58.000Z 2026-10-22T17:43:39.342Z https://longevityharbor.com/de/watch/1NlWfFH0Bhs DEREGULATED NUTRIENT SENSING & AGING | The Hallmarks of Aging [2020] https://i.ytimg.com/vi/1NlWfFH0Bhs/hqdefault.jpg DEREGULATED NUTRIENT SENSING & AGING. Today we’ll be covering one of the Hallmarks of Aging, and if you use research into drugs that can extend the human lifespan, one of the most important ones. Food is essential. We eat food to fuel our bodies so we can move and to repair and build tissues. In order for our bodies to use food as fuel, it has to recognize the nutrients and get to work breaking them down and utilizing them. Good thing our bodies have several mechanisms to make that happen. This is the latest installment on the series on The Hallmarks Of Aging. In today's video, we will go over nutrient-sensing, which pathways are involved in that and how those processes tend to change, or become deregulated, as we age. And as always, there will be discussion to go over what, if anything, can be done about reversing those changes. Tune in to learn more about how the body uses food as fuel and how that changes as we age. https://www.youtube-nocookie.com/embed/1NlWfFH0Bhs 562 2020-08-18T19:47:58.000Z 2026-10-22T17:43:39.342Z https://longevityharbor.com/en/watch/1W9z_G5PI3M Conference session on geroscience and geromedicine at the Mauritius Longevity Summit https://i.ytimg.com/vi/1W9z_G5PI3M/hqdefault.jpg According to the description, John C. Newman's session at the Mauritius Longevity Summit linked aging biology from the laboratory with clinical care and discussed geroscience-driven approaches to healthspan. https://www.youtube-nocookie.com/embed/1W9z_G5PI3M 1950 2025-12-17T06:30:52.000Z 2026-10-23T03:16:16.084Z https://longevityharbor.com/de/watch/1W9z_G5PI3M Konferenzsitzung zu Geroscience und Geromedizin beim Mauritius Longevity Summit https://i.ytimg.com/vi/1W9z_G5PI3M/hqdefault.jpg Laut Beschreibung verband John C. Newmans Sitzung beim Mauritius Longevity Summit die Biologie des Alterns aus dem Labor mit der klinischen Versorgung und diskutierte geroscience-getriebene Ansätze für die Gesundheitsspanne. https://www.youtube-nocookie.com/embed/1W9z_G5PI3M 1950 2025-12-17T06:30:52.000Z 2026-10-23T03:16:16.084Z https://longevityharbor.com/en/watch/1ablQrDq9iA Video description: beans, methionine and autophagy without fasting https://i.ytimg.com/vi/1ablQrDq9iA/hqdefault.jpg The description says legumes are low in methionine and that this may keep the autophagy window open while eating; it cites animal models and does not report human lifespan results. https://www.youtube-nocookie.com/embed/1ablQrDq9iA 1384 2026-08-07T14:00:38.000Z 2026-10-22T23:15:01.598Z https://longevityharbor.com/de/watch/1ablQrDq9iA Videobeschreibung: Bohnen, Methionin und Autophagie ohne Fasten https://i.ytimg.com/vi/1ablQrDq9iA/hqdefault.jpg Die Beschreibung nennt Hülsenfrüchte als methioninarm und sagt, dadurch könne das Autophagie-Zeitfenster beim Essen offen bleiben; sie nennt Tiermodelle und keine menschlichen Langlebigkeitsergebnisse. https://www.youtube-nocookie.com/embed/1ablQrDq9iA 1384 2026-08-07T14:00:38.000Z 2026-10-22T23:15:01.598Z https://longevityharbor.com/en/watch/1bYNdEaKJwg jungbleiben#13 Hallmarks of Aging - Beste Version von dir - Podcast https://i.ytimg.com/vi/1bYNdEaKJwg/hqdefault.jpg Nicolas Ting zu den Kennzeichen der Alterung https://www.youtube-nocookie.com/embed/1bYNdEaKJwg 2237 2024-01-16T16:06:53.000Z 2026-10-22T19:04:37.595Z https://longevityharbor.com/de/watch/1bYNdEaKJwg jungbleiben#13 Hallmarks of Aging - Beste Version von dir - Podcast https://i.ytimg.com/vi/1bYNdEaKJwg/hqdefault.jpg Nicolas Ting zu den Kennzeichen der Alterung https://www.youtube-nocookie.com/embed/1bYNdEaKJwg 2237 2024-01-16T16:06:53.000Z 2026-10-22T19:04:37.595Z https://longevityharbor.com/en/watch/1c3QNEurlQM Fit im Alter - 6 Minuten Ganzkörper Workout für Ältere ✅ Mehr Mobilität https://i.ytimg.com/vi/1c3QNEurlQM/hqdefault.jpg Wir haben für Dich ein 6 Minuten Ganzkörper Workout, welches ideal für Menschen im höheren Alter geeignet ist! Entdecke jetzt die neue Ergotopia App - inklusive kostenloser Kurse! 💙 ➞ https://www.ergotopia.de/app?utm_medium=social&utm_source=youtube&utm_campaign=description_fit_im_alter ▸ 3 umfangreiche und individuell abgestimmte Kurse für langfristige Gesundheit, Energie und Produktivität ▸ Gesunde Gewohnheiten entwickeln, um fast schon automatisch voranzukommen ▸ Geballte Expertise zum Thema Rückengesundheit, Entspannung und Wohlbefinden ▸ 100 % Kostenlos Jetzt Ergotopia App entdecken: ➞ https://www.ergotopia.de/app?utm_medium=social&utm_source=youtube&utm_campaign=description_fit_im_alter ------------------------------ #bewegung #workout #ergotopia #fitimalter #übungen Fit im Alter? Na klar ist das möglich! Wir zeigen Dir ein einfaches Workout, das besonders für Menschen über 60 Jahre geeignet ist und mit dem Du von Kopf bis Fuß fit bleibst! Nimm Dir täglich nur 6 Minuten und führe mit Sportwissenschaftlerin Nina Mammana diese einfachen Fitnessübungen durch, um fit zu bleiben. 🙃 Mobilisiere und kräftige Deinen Körper in nur 6 Minuten! Das ist nicht nur, aber besonders auch im Alter sehr wichtig. Besonders effektiv wirken die Übungen, wenn Du sie wirklich täglich machst und in Deinen Alltag einbaust. Die Übungen finden alle im Stehen statt und Du brauchst nur 2 kleine Wasserflaschen als Gewichte. Falls Du Probleme mit dem Gleichgewicht hast, nimm Dir einen Stuhl zur Seite, an dem Du Dich stützen kannst. Viel Spaß! 💙 Dir hat das Video gefallen? Abonniere unseren YouTube-Kanal für mehr Tipps & Workouts! ------------------------------ Folge uns gerne auch auf anderen Plattformen: ➞ Ergotopia Blog: https://www.ergotopia.de/blog?utm_medium=social&utm_source=youtube&utm_campaign=description_fit_im_alter ➞ Instagram: https://www.instagram.com/ergotopia.de ➞ Facebook: https://www.facebook.com/ergotopia/ ➞ X: https://twitter.com/ergotopia_de ➞ Linkedin: https://www.linkedin.com/company/ergoto https://www.youtube-nocookie.com/embed/1c3QNEurlQM 405 2020-05-19T15:00:00.000Z 2026-10-22T17:43:36.087Z https://longevityharbor.com/de/watch/1c3QNEurlQM Fit im Alter - 6 Minuten Ganzkörper Workout für Ältere ✅ Mehr Mobilität https://i.ytimg.com/vi/1c3QNEurlQM/hqdefault.jpg Wir haben für Dich ein 6 Minuten Ganzkörper Workout, welches ideal für Menschen im höheren Alter geeignet ist! Entdecke jetzt die neue Ergotopia App - inklusive kostenloser Kurse! 💙 ➞ https://www.ergotopia.de/app?utm_medium=social&utm_source=youtube&utm_campaign=description_fit_im_alter ▸ 3 umfangreiche und individuell abgestimmte Kurse für langfristige Gesundheit, Energie und Produktivität ▸ Gesunde Gewohnheiten entwickeln, um fast schon automatisch voranzukommen ▸ Geballte Expertise zum Thema Rückengesundheit, Entspannung und Wohlbefinden ▸ 100 % Kostenlos Jetzt Ergotopia App entdecken: ➞ https://www.ergotopia.de/app?utm_medium=social&utm_source=youtube&utm_campaign=description_fit_im_alter ------------------------------ #bewegung #workout #ergotopia #fitimalter #übungen Fit im Alter? Na klar ist das möglich! Wir zeigen Dir ein einfaches Workout, das besonders für Menschen über 60 Jahre geeignet ist und mit dem Du von Kopf bis Fuß fit bleibst! Nimm Dir täglich nur 6 Minuten und führe mit Sportwissenschaftlerin Nina Mammana diese einfachen Fitnessübungen durch, um fit zu bleiben. 🙃 Mobilisiere und kräftige Deinen Körper in nur 6 Minuten! Das ist nicht nur, aber besonders auch im Alter sehr wichtig. Besonders effektiv wirken die Übungen, wenn Du sie wirklich täglich machst und in Deinen Alltag einbaust. Die Übungen finden alle im Stehen statt und Du brauchst nur 2 kleine Wasserflaschen als Gewichte. Falls Du Probleme mit dem Gleichgewicht hast, nimm Dir einen Stuhl zur Seite, an dem Du Dich stützen kannst. Viel Spaß! 💙 Dir hat das Video gefallen? Abonniere unseren YouTube-Kanal für mehr Tipps & Workouts! ------------------------------ Folge uns gerne auch auf anderen Plattformen: ➞ Ergotopia Blog: https://www.ergotopia.de/blog?utm_medium=social&utm_source=youtube&utm_campaign=description_fit_im_alter ➞ Instagram: https://www.instagram.com/ergotopia.de ➞ Facebook: https://www.facebook.com/ergotopia/ ➞ X: https://twitter.com/ergotopia_de ➞ Linkedin: https://www.linkedin.com/company/ergoto https://www.youtube-nocookie.com/embed/1c3QNEurlQM 405 2020-05-19T15:00:00.000Z 2026-10-22T17:43:36.087Z https://longevityharbor.com/en/watch/1chfcfpPDjM Video description on epigenetic clocks and biological age https://i.ytimg.com/vi/1chfcfpPDjM/hqdefault.jpg The description says epigenetic clocks estimate biological rather than chronological age from DNA methylation patterns, and that the video covers ageing biomarkers, lifestyle influence and possible uses in preventive care and longevity research. No results are reported. https://www.youtube-nocookie.com/embed/1chfcfpPDjM 446 2026-02-25T07:56:49.000Z 2026-10-23T02:20:23.704Z https://longevityharbor.com/de/watch/1chfcfpPDjM Videobeschreibung zu epigenetischen Uhren und biologischem Alter https://i.ytimg.com/vi/1chfcfpPDjM/hqdefault.jpg Laut Beschreibung schätzen epigenetische Uhren anhand von DNA-Methylierungsmustern das biologische statt des chronologischen Alters; das Video behandelt Alterungsbiomarker, Lifestyle-Einflüsse und mögliche Nutzung in Vorsorge und Langlebigkeitsforschung. Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/1chfcfpPDjM 446 2026-02-25T07:56:49.000Z 2026-10-23T02:20:23.704Z https://longevityharbor.com/en/watch/1fq21kCXMDg Video description: three Japanese leg exercises claimed to support strength in later life https://i.ytimg.com/vi/1fq21kCXMDg/hqdefault.jpg The description presents Heel Raises, Deep Squat and Sanpo as exercises Japanese longevity experts recommend to rebuild leg strength, balance and mobility at any age. It offers no study data and says the video is educational, not medical advice. https://www.youtube-nocookie.com/embed/1fq21kCXMDg 462 2026-09-24T02:59:24.000Z 2026-10-22T21:51:37.679Z https://longevityharbor.com/de/watch/1fq21kCXMDg Videobeschreibung: drei japanische Beinübungen als angebliche Stütze für Kraft im Alter https://i.ytimg.com/vi/1fq21kCXMDg/hqdefault.jpg Die Beschreibung stellt Fersenheben, tiefe Kniebeuge und Sanpo als Übungen vor, die japanische Langlebigkeitsexperten empfehlen, um Beinkraft, Gleichgewicht und Mobilität in jedem Alter wieder aufzubauen. Sie nennt keine Studiendaten und bezeichnet das Video als Bildungsinhalt, nicht als medizinischen Rat. https://www.youtube-nocookie.com/embed/1fq21kCXMDg 462 2026-09-24T02:59:24.000Z 2026-10-22T21:51:37.679Z https://longevityharbor.com/en/watch/1gDnROQePRA Calorie Restriction And Fasting Extend Lifespan https://i.ytimg.com/vi/1gDnROQePRA/hqdefault.jpg Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD Discount Links/Affiliates: Blood testing (where I get the majority of my labs): https://www.ultalabtests.com/partners/michaellustgarten At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten Use Code: CONQUERAGING At Checkout Clearly Filtered Water Filter: https://get.aspr.app/SHoPY Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ62UkAVXBWtRVKJUM0&irgwc=1 Use Code: CONQUERAGING NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/ Use Code: ConquerAging At Checkout Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten Enter Code: ConquerAging SiphoxHealth Blood Testing (ApoB, GrimAge): https://getquantify.io/mlustgarten Green Tea: https://www.ochaandco.com/?ref=fqbtflod Use Code: ML10OFF Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack= If you'd like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/ --------------------------------------------------------------------------------------------------------------------------- Paper referenced in the video: Dietary restriction impacts health and lifespan of genetically diverse mice https://www.nature.com/articles/s41586-024-08026-3 https://www.youtube-nocookie.com/embed/1gDnROQePRA 4458 2025-02-23T12:00:04.000Z 2026-10-22T18:32:09.963Z https://longevityharbor.com/de/watch/1gDnROQePRA Calorie Restriction And Fasting Extend Lifespan https://i.ytimg.com/vi/1gDnROQePRA/hqdefault.jpg Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD Discount Links/Affiliates: Blood testing (where I get the majority of my labs): https://www.ultalabtests.com/partners/michaellustgarten At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten Use Code: CONQUERAGING At Checkout Clearly Filtered Water Filter: https://get.aspr.app/SHoPY Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ62UkAVXBWtRVKJUM0&irgwc=1 Use Code: CONQUERAGING NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/ Use Code: ConquerAging At Checkout Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten Enter Code: ConquerAging SiphoxHealth Blood Testing (ApoB, GrimAge): https://getquantify.io/mlustgarten Green Tea: https://www.ochaandco.com/?ref=fqbtflod Use Code: ML10OFF Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack= If you'd like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/ --------------------------------------------------------------------------------------------------------------------------- Paper referenced in the video: Dietary restriction impacts health and lifespan of genetically diverse mice https://www.nature.com/articles/s41586-024-08026-3 https://www.youtube-nocookie.com/embed/1gDnROQePRA 4458 2025-02-23T12:00:04.000Z 2026-10-22T18:32:09.963Z https://longevityharbor.com/en/watch/1njEqxeXugw NAD or NMN for anti aging and longevity? #nad #nmn #antiaging #tiktokshopspringglowup https://i.ytimg.com/vi/1njEqxeXugw/hqdefault.jpg NAD or NMN for anti aging and longevity? #nad #nmn #antiaging #tiktokshopspringglowup #tiktokshopcreatorpicks https://www.youtube-nocookie.com/embed/1njEqxeXugw 138 2026-08-11T17:11:13.000Z 2026-10-22T19:32:37.683Z https://longevityharbor.com/de/watch/1njEqxeXugw NAD or NMN for anti aging and longevity? #nad #nmn #antiaging #tiktokshopspringglowup https://i.ytimg.com/vi/1njEqxeXugw/hqdefault.jpg NAD or NMN for anti aging and longevity? #nad #nmn #antiaging #tiktokshopspringglowup #tiktokshopcreatorpicks https://www.youtube-nocookie.com/embed/1njEqxeXugw 138 2026-08-11T17:11:13.000Z 2026-10-22T19:32:37.683Z https://longevityharbor.com/en/watch/1qf75ZhzMF8 𝗠𝗘𝗧𝗛𝗬𝗟𝗔𝗧𝗜𝗢𝗡 𝗕𝗜𝗢𝗠𝗔𝗥𝗞𝗘𝗥𝗦 𝗢𝗙 𝗔𝗚𝗜𝗡𝗚 𝗘𝗫𝗣𝗟𝗔𝗜𝗡𝗘𝗗 | 𝗘𝗣𝗜𝗚𝗘𝗡𝗘𝗧𝗜 https://i.ytimg.com/vi/1qf75ZhzMF8/hqdefault.jpg Discover how DNA methylation biomarkers—also known as epigenetic clocks—are revolutionizing our understanding of aging and longevity. Learn how these powerful tools estimate biological age, guide anti-aging interventions, and predict disease risk. Featuring top commercial players like TruDiagnostic, EpiAging, and Deep Longevity, this video breaks down how methylation-based tests are transforming preventive healthcare and personalized medicine. #Epigenetics #BiologicalAge #AgingBiomarkers #LongevityScience #Methylation #TruDiagnostic #DeepLongevity #AntiAging #PrecisionMedicine #DNA #HealthTech #AgeReversal #EpigeneticClock #myDNAge #GrimAge #DunedinPACE #Biohacking #HealthOptimization #FutureOfMedicine https://www.youtube-nocookie.com/embed/1qf75ZhzMF8 340 2025-08-31T04:00:04.000Z 2026-10-22T18:32:06.795Z https://longevityharbor.com/de/watch/1qf75ZhzMF8 𝗠𝗘𝗧𝗛𝗬𝗟𝗔𝗧𝗜𝗢𝗡 𝗕𝗜𝗢𝗠𝗔𝗥𝗞𝗘𝗥𝗦 𝗢𝗙 𝗔𝗚𝗜𝗡𝗚 𝗘𝗫𝗣𝗟𝗔𝗜𝗡𝗘𝗗 | 𝗘𝗣𝗜𝗚𝗘𝗡𝗘𝗧𝗜 https://i.ytimg.com/vi/1qf75ZhzMF8/hqdefault.jpg Discover how DNA methylation biomarkers—also known as epigenetic clocks—are revolutionizing our understanding of aging and longevity. Learn how these powerful tools estimate biological age, guide anti-aging interventions, and predict disease risk. Featuring top commercial players like TruDiagnostic, EpiAging, and Deep Longevity, this video breaks down how methylation-based tests are transforming preventive healthcare and personalized medicine. #Epigenetics #BiologicalAge #AgingBiomarkers #LongevityScience #Methylation #TruDiagnostic #DeepLongevity #AntiAging #PrecisionMedicine #DNA #HealthTech #AgeReversal #EpigeneticClock #myDNAge #GrimAge #DunedinPACE #Biohacking #HealthOptimization #FutureOfMedicine https://www.youtube-nocookie.com/embed/1qf75ZhzMF8 340 2025-08-31T04:00:04.000Z 2026-10-22T18:32:06.795Z https://longevityharbor.com/en/watch/1sQAiDy8lLE Mitochondria and Aging https://i.ytimg.com/vi/1sQAiDy8lLE/hqdefault.jpg Researchers have identified several molecular pathways at a cellular level, including within the mitochondria, which appear to influence both aging and age-related chronic disease. These cellular changes associated with aging are cumulatively referred to as age-associated cellular decline, or AACD. Identifying AACD risk factors and intervening with cellular nutrients earlier in the aging process, before major mobility disabilities and disease driven limitations emerge, could help improve overall healthy aging.  A set of three podcast discussions from the panel of the What’s Hot on Cellular Nutrition and Its Influence on Age-Associated Cellular Decline (https://www.geron.org/images/gsa/documents/whatshotcellularnutrition.pdf) , explores various elements of AACD and the care of older adults. This episode focuses specifically on what researchers are learning about the importance of mitochondrial function. Download the Transcript (https://gsaenrich.geron.org/files/1179060) Guest: Anthony J. A. Molina, PhD Vice Chief of Research, Division of Geriatrics, Gerontology, and Palliative Care, University of California San Diego School of Medicine  Associate Professor, Department of Medicine, University of California San Diego School of Medicine  Host: Roger A. Fielding, PhD Associate Director, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University Lead Scientist and Senior Scientist Nutrition, Exercise Physiology, and Sarcopenia Team, Tufts University Professor of Nutrition Friedman School of Nutrition Science and Policy, Tufts University Professor of Medicine, Tufts University School of Medicine Associate Director, Boston Claude D. Pepper Older Americans Independence Center This podcast series was developed by The Gerontological Society of America (GSA) (http://geron.org) .  This program has received a grant from Nestle Health Science (https://www.nestlehealthscience.com/) . https://www.youtube-nocookie.com/embed/1sQAiDy8lLE 991 2024-06-10T14:23:18.000Z 2026-10-22T17:43:40.124Z https://longevityharbor.com/de/watch/1sQAiDy8lLE Mitochondria and Aging https://i.ytimg.com/vi/1sQAiDy8lLE/hqdefault.jpg Researchers have identified several molecular pathways at a cellular level, including within the mitochondria, which appear to influence both aging and age-related chronic disease. These cellular changes associated with aging are cumulatively referred to as age-associated cellular decline, or AACD. Identifying AACD risk factors and intervening with cellular nutrients earlier in the aging process, before major mobility disabilities and disease driven limitations emerge, could help improve overall healthy aging.  A set of three podcast discussions from the panel of the What’s Hot on Cellular Nutrition and Its Influence on Age-Associated Cellular Decline (https://www.geron.org/images/gsa/documents/whatshotcellularnutrition.pdf) , explores various elements of AACD and the care of older adults. This episode focuses specifically on what researchers are learning about the importance of mitochondrial function. Download the Transcript (https://gsaenrich.geron.org/files/1179060) Guest: Anthony J. A. Molina, PhD Vice Chief of Research, Division of Geriatrics, Gerontology, and Palliative Care, University of California San Diego School of Medicine  Associate Professor, Department of Medicine, University of California San Diego School of Medicine  Host: Roger A. Fielding, PhD Associate Director, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University Lead Scientist and Senior Scientist Nutrition, Exercise Physiology, and Sarcopenia Team, Tufts University Professor of Nutrition Friedman School of Nutrition Science and Policy, Tufts University Professor of Medicine, Tufts University School of Medicine Associate Director, Boston Claude D. Pepper Older Americans Independence Center This podcast series was developed by The Gerontological Society of America (GSA) (http://geron.org) .  This program has received a grant from Nestle Health Science (https://www.nestlehealthscience.com/) . https://www.youtube-nocookie.com/embed/1sQAiDy8lLE 991 2024-06-10T14:23:18.000Z 2026-10-22T17:43:40.124Z https://longevityharbor.com/en/watch/1u5PupzYrBE Webinar description: senescent cells, SASP and senolytic research https://i.ytimg.com/vi/1u5PupzYrBE/hqdefault.jpg The description announces an educational webinar on cellular senescence, the senescence-associated secretory phenotype (SASP), and senotherapeutic strategies, naming senolytics such as dasatinib plus quercetin and fisetin and intermittent dosing. It states the webinar gives no medical advice. https://www.youtube-nocookie.com/embed/1u5PupzYrBE 3576 2026-03-11T18:34:46.000Z 2026-10-23T02:10:08.316Z https://longevityharbor.com/de/watch/1u5PupzYrBE Webinar-Beschreibung: seneszente Zellen, SASP und Senolytika-Forschung https://i.ytimg.com/vi/1u5PupzYrBE/hqdefault.jpg Die Beschreibung kündigt ein Schulungs-Webinar über zelluläre Seneszenz, den seneszenzassoziierten sekretorischen Phänotyp (SASP) und senotherapeutische Strategien an, nennt Senolytika wie Dasatinib plus Quercetin und Fisetin sowie intermittierende Dosierung. Medizinische Beratung gebe das Webinar nicht, so die Beschreibung. https://www.youtube-nocookie.com/embed/1u5PupzYrBE 3576 2026-03-11T18:34:46.000Z 2026-10-23T02:10:08.316Z https://longevityharbor.com/en/watch/220KHIdFCwg Video description: lymphopenia, IL-15 and ANKTIVA as a proposed longevity drug https://i.ytimg.com/vi/220KHIdFCwg/hqdefault.jpg The description presents lymphopenia as linked to higher mortality in three cohort studies and ANKTIVA as the first FDA-approved IL-15 super-agonist, approved for bladder cancer; a longevity role is called an untested hypothesis. https://www.youtube-nocookie.com/embed/220KHIdFCwg 779 2026-05-24T23:18:42.000Z 2026-10-23T00:26:16.814Z https://longevityharbor.com/de/watch/220KHIdFCwg Videobeschreibung: Lymphopenie, IL-15 und ANKTIVA als vorgeschlagenes Langlebigkeitsmedikament https://i.ytimg.com/vi/220KHIdFCwg/hqdefault.jpg Die Beschreibung stellt Lymphopenie in drei Kohortenstudien als mit höherer Sterblichkeit verbunden dar und ANKTIVA als ersten von der FDA zugelassenen IL-15-Superagonisten, zugelassen für Blasenkrebs; eine Rolle für Langlebigkeit wird als ungeprüfte Hypothese bezeichnet. https://www.youtube-nocookie.com/embed/220KHIdFCwg 779 2026-05-24T23:18:42.000Z 2026-10-23T00:26:16.814Z https://longevityharbor.com/en/watch/27jcwfrboyc [OAP] Prescriptions for Aging Well: Muscle, Strength and Protein Matter https://i.ytimg.com/vi/27jcwfrboyc/hqdefault.jpg Join us for another installment in the Optimal Aging Portal Health & Wellness Series.   In this upcoming one-hour webinar with Dr. Stuart Phillips, Professor of Kinesiology and a leading researcher in the field, he will share how strength training and protein intake can help older adults maintain muscle, improve mobility, and support overall well-being. This session will offer evidence-based advice and simple strategies to help you age actively and confidently. Whether you're new to this form of exercise or curious about how much protein you really need as you age, you don't want to miss this opportunity to hear from one of Canada’s most prominent researchers on skeletal muscle health. This talk is part of the Optimal Aging Portal Webinar Series, a great resource of evidence-based healthy aging information, and is hosted by Dr. Anthony Levinson. All talks are recorded and archived for future viewing. About our speaker: Stuart Phillips, PhD, is a Canada Research Chair and Professor of Kinesiology at McMaster University and serves as the Director of the Physical Activity Centre of Excellence (PACE). He is a fellow of the Canadian Academy of Science and the American College of Sports Medicine. He is also a 5-time nominee and 3-time recipient of the McMaster Student's Union Teaching Award. His research centers on the roles exercise and nutrition play in influencing human skeletal muscle health in aging. https://www.youtube-nocookie.com/embed/27jcwfrboyc 4264 2025-09-25T00:20:33.000Z 2026-10-22T18:54:06.023Z https://longevityharbor.com/de/watch/27jcwfrboyc [OAP] Prescriptions for Aging Well: Muscle, Strength and Protein Matter https://i.ytimg.com/vi/27jcwfrboyc/hqdefault.jpg Join us for another installment in the Optimal Aging Portal Health & Wellness Series.   In this upcoming one-hour webinar with Dr. Stuart Phillips, Professor of Kinesiology and a leading researcher in the field, he will share how strength training and protein intake can help older adults maintain muscle, improve mobility, and support overall well-being. This session will offer evidence-based advice and simple strategies to help you age actively and confidently. Whether you're new to this form of exercise or curious about how much protein you really need as you age, you don't want to miss this opportunity to hear from one of Canada’s most prominent researchers on skeletal muscle health. This talk is part of the Optimal Aging Portal Webinar Series, a great resource of evidence-based healthy aging information, and is hosted by Dr. Anthony Levinson. All talks are recorded and archived for future viewing. About our speaker: Stuart Phillips, PhD, is a Canada Research Chair and Professor of Kinesiology at McMaster University and serves as the Director of the Physical Activity Centre of Excellence (PACE). He is a fellow of the Canadian Academy of Science and the American College of Sports Medicine. He is also a 5-time nominee and 3-time recipient of the McMaster Student's Union Teaching Award. His research centers on the roles exercise and nutrition play in influencing human skeletal muscle health in aging. https://www.youtube-nocookie.com/embed/27jcwfrboyc 4264 2025-09-25T00:20:33.000Z 2026-10-22T18:54:06.023Z https://longevityharbor.com/en/watch/2D2CD0gnAYM Andrea Maier at ARDD2025: Epigenetic clocks Working group https://i.ytimg.com/vi/2D2CD0gnAYM/hqdefault.jpg Andrea Maier, National University of Singapore, presents at the 12th Aging Research and Drug Discovery meeting: Epigenetic clocks Working group https://www.youtube-nocookie.com/embed/2D2CD0gnAYM 1401 2026-03-06T13:18:35.000Z 2026-10-22T19:21:27.609Z https://longevityharbor.com/de/watch/2D2CD0gnAYM Andrea Maier at ARDD2025: Epigenetic clocks Working group https://i.ytimg.com/vi/2D2CD0gnAYM/hqdefault.jpg Andrea Maier, National University of Singapore, presents at the 12th Aging Research and Drug Discovery meeting: Epigenetic clocks Working group https://www.youtube-nocookie.com/embed/2D2CD0gnAYM 1401 2026-03-06T13:18:35.000Z 2026-10-22T19:21:27.609Z https://longevityharbor.com/en/watch/2EIzwKGzmE4 Intermittent Fasting: A Strategy To Prevent Cardiometabolic Diseases And Promote Healthy Aging https://i.ytimg.com/vi/2EIzwKGzmE4/hqdefault.jpg Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explores the science and clinical evidence behind intermittent fasting and its role in promoting cardiometabolic health. He explains how aligning eating patterns with the body’s natural circadian rhythms can improve weight, blood pressure, glucose regulation, and other risk factors, especially in individuals with metabolic syndrome or type 2 diabetes. Wilkinson highlights promising results from time-restricted eating studies conducted in collaboration with UC San Diego and the Salk Institute, where narrowing the daily eating window led to improved metabolic markers and potential benefits beyond weight loss. He also outlines practical tips for safely adopting this lifestyle approach and stresses the importance of ongoing research. [Show ID: 40319] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/2EIzwKGzmE4 3271 2025-08-23T02:00:02.000Z 2026-10-22T17:43:38.440Z https://longevityharbor.com/de/watch/2EIzwKGzmE4 Intermittent Fasting: A Strategy To Prevent Cardiometabolic Diseases And Promote Healthy Aging https://i.ytimg.com/vi/2EIzwKGzmE4/hqdefault.jpg Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explores the science and clinical evidence behind intermittent fasting and its role in promoting cardiometabolic health. He explains how aligning eating patterns with the body’s natural circadian rhythms can improve weight, blood pressure, glucose regulation, and other risk factors, especially in individuals with metabolic syndrome or type 2 diabetes. Wilkinson highlights promising results from time-restricted eating studies conducted in collaboration with UC San Diego and the Salk Institute, where narrowing the daily eating window led to improved metabolic markers and potential benefits beyond weight loss. He also outlines practical tips for safely adopting this lifestyle approach and stresses the importance of ongoing research. [Show ID: 40319] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/2EIzwKGzmE4 3271 2025-08-23T02:00:02.000Z 2026-10-22T17:43:38.440Z https://longevityharbor.com/en/watch/2If31DruBsg Caloric restriction's impact on muscle mass, strength, and the immune system | Matt Kaeberlein https://i.ytimg.com/vi/2If31DruBsg/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/4sqyGwqyAao Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 222 - How nutrition impacts longevity with Matt Kaeberlein, Ph.D. In this clip, they discuss: - Challenges in studying caloric restriction (CR) in laboratory animals vs. real-world humans - Effects of CR on immune function, frailty, and sarcopenia in controlled studies - Risks, downsides, and uncertainties of caloric restriction as a therapeutic strategy - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or de https://www.youtube-nocookie.com/embed/2If31DruBsg 605 2025-01-22T17:00:01.000Z 2026-10-22T17:43:38.463Z https://longevityharbor.com/de/watch/2If31DruBsg Caloric restriction's impact on muscle mass, strength, and the immune system | Matt Kaeberlein https://i.ytimg.com/vi/2If31DruBsg/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/4sqyGwqyAao Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 222 - How nutrition impacts longevity with Matt Kaeberlein, Ph.D. In this clip, they discuss: - Challenges in studying caloric restriction (CR) in laboratory animals vs. real-world humans - Effects of CR on immune function, frailty, and sarcopenia in controlled studies - Risks, downsides, and uncertainties of caloric restriction as a therapeutic strategy - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or de https://www.youtube-nocookie.com/embed/2If31DruBsg 605 2025-01-22T17:00:01.000Z 2026-10-22T17:43:38.463Z https://longevityharbor.com/en/watch/2LOjvT5L0dc Video description: wild herbs said to support a healthy diet https://i.ytimg.com/vi/2LOjvT5L0dc/hqdefault.jpg The description says wild herbs are rich in bitter compounds, vitamins and minerals and can support a healthy diet; it gives no study, amounts or evidence. https://www.youtube-nocookie.com/embed/2LOjvT5L0dc 123 2026-03-15T14:20:47.000Z 2026-10-23T02:05:41.784Z https://longevityharbor.com/de/watch/2LOjvT5L0dc Videobeschreibung: Wildkräuter als angebliche Unterstützung gesunder Ernährung https://i.ytimg.com/vi/2LOjvT5L0dc/hqdefault.jpg Die Beschreibung nennt Wildkräuter reich an Bitterstoffen, Vitaminen und Mineralien und als Unterstützung gesunder Ernährung; Studien, Mengen oder Belege fehlen. https://www.youtube-nocookie.com/embed/2LOjvT5L0dc 123 2026-03-15T14:20:47.000Z 2026-10-23T02:05:41.784Z https://longevityharbor.com/en/watch/2LthFi6v_c8 Video description: fasting-mimicking diet discussed by Prof. Reuter https://i.ytimg.com/vi/2LthFi6v_c8/hqdefault.jpg The description announces a QS24 studio talk with Prof. Dr. Uwe Reuter on the fasting-mimicking diet: how it is said to work, how it differs from classic fasting, and which studies and clinical experiences are to be discussed. https://www.youtube-nocookie.com/embed/2LthFi6v_c8 1659 2026-08-17T18:00:39.000Z 2026-10-22T22:56:54.955Z https://longevityharbor.com/de/watch/2LthFi6v_c8 Videobeschreibung: Scheinfasten im Gespräch mit Prof. Reuter https://i.ytimg.com/vi/2LthFi6v_c8/hqdefault.jpg Die Beschreibung kündigt ein QS24-Studiogespräch mit Prof. Dr. Uwe Reuter über Scheinfasten an: wie es laut Ankündigung wirken soll, wie es sich vom klassischen Fasten unterscheidet und welche Studien und klinischen Erfahrungen besprochen werden sollen. https://www.youtube-nocookie.com/embed/2LthFi6v_c8 1659 2026-08-17T18:00:39.000Z 2026-10-22T22:56:54.955Z https://longevityharbor.com/en/watch/2MjFrRmth9k Wall sit vs step-ups: described muscle demands after 60 https://i.ytimg.com/vi/2MjFrRmth9k/hqdefault.jpg The description says wall sits and step-ups both strengthen legs but demand different things: a steady hold versus movement, balance and repeated force. It frames a biomechanics comparison, not a proven winner. https://www.youtube-nocookie.com/embed/2MjFrRmth9k 917 2026-08-09T12:30:28.000Z 2026-10-22T23:08:05.236Z https://longevityharbor.com/de/watch/2MjFrRmth9k Wandsitz vs. Step-ups: beschriebene Muskelanforderungen nach 60 https://i.ytimg.com/vi/2MjFrRmth9k/hqdefault.jpg Laut Beschreibung stärken Wandsitz und Step-ups beide die Beine, verlangen aber Unterschiedliches: ruhiges Halten gegenüber Bewegung, Gleichgewicht und wiederholter Kraft. Sie rahmt einen Biomechanik-Vergleich ein, keinen belegten Sieger. https://www.youtube-nocookie.com/embed/2MjFrRmth9k 917 2026-08-09T12:30:28.000Z 2026-10-22T23:08:05.236Z https://longevityharbor.com/en/watch/2Ni7kYGuYIc NR vs NMN: Which NAD+ Booster Wins for Real Energy & Anti-Aging? (Research Guide) https://i.ytimg.com/vi/2Ni7kYGuYIc/hqdefault.jpg Feeling constantly run-down? It's not just age—your NAD+ levels drop! In this research-backed guide, we compare NR (Nicotinamide Riboside – the gold standard with most human trials) vs NMN (the biohacking favorite) to see which precursor actually boosts cellular energy best. Discover why NAD+ is your body's "energy delivery truck," how precursors help rebuild it, dosing tips (250-300mg morning), quality red flags (third-party tested + GMP), and why supplements shine when paired with exercise, sleep, and nutrition. No magic pill—just smart science support for your mitochondria! Full guide + high-quality options: https://VibranceWay.com Timestamps: 0:00 – Why NAD+ Matters as You Age 1:20 – NAD+ as Your Cell's Delivery Truck 2:45 – NR: The Research-Backed Gold Standard 4:10 – NMN: Biohacker Favorite Explained 5:30 – Quality & Dosing Tips 6:45 – Lifestyle Wins Over Supplements Alone 7:50 – Final Verdict & Next Steps Like, subscribe & hit the bell for more practical wellness science! #NADPlus #NRvsNMN #AntiAging #CellularEnergy #Biohacking #Longevity #WellnessTips #VibranceWay https://www.youtube-nocookie.com/embed/2Ni7kYGuYIc 152 2026-02-15T14:00:05.000Z 2026-10-22T20:11:48.399Z https://longevityharbor.com/de/watch/2Ni7kYGuYIc NR vs NMN: Which NAD+ Booster Wins for Real Energy & Anti-Aging? (Research Guide) https://i.ytimg.com/vi/2Ni7kYGuYIc/hqdefault.jpg Feeling constantly run-down? It's not just age—your NAD+ levels drop! In this research-backed guide, we compare NR (Nicotinamide Riboside – the gold standard with most human trials) vs NMN (the biohacking favorite) to see which precursor actually boosts cellular energy best. Discover why NAD+ is your body's "energy delivery truck," how precursors help rebuild it, dosing tips (250-300mg morning), quality red flags (third-party tested + GMP), and why supplements shine when paired with exercise, sleep, and nutrition. No magic pill—just smart science support for your mitochondria! Full guide + high-quality options: https://VibranceWay.com Timestamps: 0:00 – Why NAD+ Matters as You Age 1:20 – NAD+ as Your Cell's Delivery Truck 2:45 – NR: The Research-Backed Gold Standard 4:10 – NMN: Biohacker Favorite Explained 5:30 – Quality & Dosing Tips 6:45 – Lifestyle Wins Over Supplements Alone 7:50 – Final Verdict & Next Steps Like, subscribe & hit the bell for more practical wellness science! #NADPlus #NRvsNMN #AntiAging #CellularEnergy #Biohacking #Longevity #WellnessTips #VibranceWay https://www.youtube-nocookie.com/embed/2Ni7kYGuYIc 152 2026-02-15T14:00:05.000Z 2026-10-22T20:11:48.399Z https://longevityharbor.com/en/watch/2Pqm1VwNiIU Video description: eight proposed keys to healthy longevity https://i.ytimg.com/vi/2Pqm1VwNiIU/hqdefault.jpg The description presents a talk by Ralph Steuernagel on healthy longevity, centred on preserving healthspan rather than only extending lifespan, and lists eight proposed keys. https://www.youtube-nocookie.com/embed/2Pqm1VwNiIU 4507 2026-10-04T07:00:03.000Z 2026-10-22T21:28:19.472Z https://longevityharbor.com/de/watch/2Pqm1VwNiIU Videobeschreibung: acht vorgeschlagene Schlüssel für gesundes Altern https://i.ytimg.com/vi/2Pqm1VwNiIU/hqdefault.jpg Die Beschreibung stellt einen Vortrag von Ralph Steuernagel über gesundes Altern vor, der auf den Erhalt der Gesundheitsspanne statt nur der Lebenszeit zielt, und nennt acht vorgeschlagene Schlüssel. https://www.youtube-nocookie.com/embed/2Pqm1VwNiIU 4507 2026-10-04T07:00:03.000Z 2026-10-22T21:28:19.472Z https://longevityharbor.com/en/watch/2UN_EO6QXvY Rapamycin may slow aging. Here's one way the drug will be tested (via Allison Aubrey/NPR) https://i.ytimg.com/vi/2UN_EO6QXvY/hqdefault.jpg Rapamycin may slow aging. Here's one way the drug will be tested SUPPORT THE CHANNEL ➡️ Subscribe: https://tinyurl.com/medxclusiveSUB ➡️ Blog: https://medXclusive.org ➡️ Subscribe to us for Medicine, Preventive Medicine, Board Exams' High Yield Review + QBank, Health Tips, & Patient Awareness. ➡️ Check out our playlists: USMLE High Yield Qbank: https://youtu.be/RtCBukwxPMw Medical High Yield Review: https://youtu.be/GRulrRJdTJ4 Medical Up-to-Date: https://youtu.be/ZuU6LpsSkiA Medical Animation: https://youtu.be/EeE7Fpg061I Medical Topics: https://youtu.be/jpTeSWML9ks Preventative Medicine: https://youtu.be/CaaoU0tsTFQ For Complete list of Playlists, Visit: https://www.youtube.com/medxclusivelearnings CREDITS: ➡️ Music: https://www.youtube.com/channel/UCroT3lzmdQUabW1WAiyWsFQ Trends: medical lectures, medical education, medical news, medical school, medical student, healthcare, health education, health news, medicine, medicina, research news, research, medxclusive, medxclusive learning —————————————————————————————————————- This channel is directed towards healthcare professionals, students, & individuals with a genuine interest in medical education. As members of the medical community, it is imperative to remember that healthcare is centered around care & compassion. Our objective is to offer accessible & up-to-date medical information through written materials (blog) & multimedia content. Our hope is that this platform serves as a useful resource for exam preparation & staying current with medical news - for free. Subscribe for Medical News, Preventive Medicine, Board Exam Review + Qbank, Health Tips & Patient awareness videos. Hope you support us in our journey! *Disclaimer: The information provided on this channel is for educational purposes only & is not intended as medical advice or diagnosis. Please consult a licensed healthcare provider for personal medical advice & treatment.* Any Video Clips Used - are used with permission or under fair use: Section 105 of the Copyright Act (17 U.S.C. § 105 https://www.youtube-nocookie.com/embed/2UN_EO6QXvY 188 2024-07-03T02:20:02.000Z 2026-10-22T19:32:35.594Z https://longevityharbor.com/de/watch/2UN_EO6QXvY Rapamycin may slow aging. Here's one way the drug will be tested (via Allison Aubrey/NPR) https://i.ytimg.com/vi/2UN_EO6QXvY/hqdefault.jpg Rapamycin may slow aging. Here's one way the drug will be tested SUPPORT THE CHANNEL ➡️ Subscribe: https://tinyurl.com/medxclusiveSUB ➡️ Blog: https://medXclusive.org ➡️ Subscribe to us for Medicine, Preventive Medicine, Board Exams' High Yield Review + QBank, Health Tips, & Patient Awareness. ➡️ Check out our playlists: USMLE High Yield Qbank: https://youtu.be/RtCBukwxPMw Medical High Yield Review: https://youtu.be/GRulrRJdTJ4 Medical Up-to-Date: https://youtu.be/ZuU6LpsSkiA Medical Animation: https://youtu.be/EeE7Fpg061I Medical Topics: https://youtu.be/jpTeSWML9ks Preventative Medicine: https://youtu.be/CaaoU0tsTFQ For Complete list of Playlists, Visit: https://www.youtube.com/medxclusivelearnings CREDITS: ➡️ Music: https://www.youtube.com/channel/UCroT3lzmdQUabW1WAiyWsFQ Trends: medical lectures, medical education, medical news, medical school, medical student, healthcare, health education, health news, medicine, medicina, research news, research, medxclusive, medxclusive learning —————————————————————————————————————- This channel is directed towards healthcare professionals, students, & individuals with a genuine interest in medical education. As members of the medical community, it is imperative to remember that healthcare is centered around care & compassion. Our objective is to offer accessible & up-to-date medical information through written materials (blog) & multimedia content. Our hope is that this platform serves as a useful resource for exam preparation & staying current with medical news - for free. Subscribe for Medical News, Preventive Medicine, Board Exam Review + Qbank, Health Tips & Patient awareness videos. Hope you support us in our journey! *Disclaimer: The information provided on this channel is for educational purposes only & is not intended as medical advice or diagnosis. Please consult a licensed healthcare provider for personal medical advice & treatment.* Any Video Clips Used - are used with permission or under fair use: Section 105 of the Copyright Act (17 U.S.C. § 105 https://www.youtube-nocookie.com/embed/2UN_EO6QXvY 188 2024-07-03T02:20:02.000Z 2026-10-22T19:32:35.594Z https://longevityharbor.com/en/watch/2UZtvn2N7Eg Der Stoffwechsel-Experte: Prof Dr. Lenhard Rudolph über Kalorienrestriktion & Gesundes Altern https://i.ytimg.com/vi/2UZtvn2N7Eg/hqdefault.jpg In diesem Podcast spreche ich mit Prof. Dr. Karl Lenhard Rudolph über die Auswirkungen von Kalorienrestriktion (z.B. FDH) auf die Alterung. Professor Rudolf ist Stammzellen- und Stoffwechsel-Experte am Leibniz Institut für Alternsforschung in Jena.   In dieser Folge sprechen wir über: -  Funktion und Wirkung den Diabetes-Medikamentes Metformin auf die Zellalterung. -  Wie das Medikament Rapamyzin auf die Zellalterung wirkt. -  Weshalb die Diät Restriktion vielleicht das einfachste und beste Mittel für gesunde Langlebigkeit ist. -  Weshalb Diät Restriktion nicht nur Verzicht bedeutet. - Wie unser Wachstumshormon sich auf unsere Langlebigkeit auswirkt. - Welche Forschungen zurzeit zum Thema durchgeführt werden. - Was wir an Selbstversuchen bereits getestet haben.   Weitere Informationen zu Prof. Dr. Rudolph und seinem Forschungsteam findest du hier: ⁠https://www.leibniz-fli.de/de/forschung/forschungsgruppen/rudolph⁠ (STY-5) Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen, wende dich bitte an deinen Arzt/deine Ärztin. https://www.youtube-nocookie.com/embed/2UZtvn2N7Eg 3408 2024-03-08T05:00:07.000Z 2026-10-22T19:04:43.811Z https://longevityharbor.com/de/watch/2UZtvn2N7Eg Der Stoffwechsel-Experte: Prof Dr. Lenhard Rudolph über Kalorienrestriktion & Gesundes Altern https://i.ytimg.com/vi/2UZtvn2N7Eg/hqdefault.jpg In diesem Podcast spreche ich mit Prof. Dr. Karl Lenhard Rudolph über die Auswirkungen von Kalorienrestriktion (z.B. FDH) auf die Alterung. Professor Rudolf ist Stammzellen- und Stoffwechsel-Experte am Leibniz Institut für Alternsforschung in Jena.   In dieser Folge sprechen wir über: -  Funktion und Wirkung den Diabetes-Medikamentes Metformin auf die Zellalterung. -  Wie das Medikament Rapamyzin auf die Zellalterung wirkt. -  Weshalb die Diät Restriktion vielleicht das einfachste und beste Mittel für gesunde Langlebigkeit ist. -  Weshalb Diät Restriktion nicht nur Verzicht bedeutet. - Wie unser Wachstumshormon sich auf unsere Langlebigkeit auswirkt. - Welche Forschungen zurzeit zum Thema durchgeführt werden. - Was wir an Selbstversuchen bereits getestet haben.   Weitere Informationen zu Prof. Dr. Rudolph und seinem Forschungsteam findest du hier: ⁠https://www.leibniz-fli.de/de/forschung/forschungsgruppen/rudolph⁠ (STY-5) Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen, wende dich bitte an deinen Arzt/deine Ärztin. https://www.youtube-nocookie.com/embed/2UZtvn2N7Eg 3408 2024-03-08T05:00:07.000Z 2026-10-22T19:04:43.811Z https://longevityharbor.com/en/watch/2_sMFBuY3y4 Why High Protein Diets Could Be Dangerous | Dr. Valter Longo https://i.ytimg.com/vi/2_sMFBuY3y4/hqdefault.jpg Excess protein may dramatically increase the risk of cancer and accelerate aging. Dr. Valter Longo, one of the top scientists in aging research and creator of the Fasting Mimicking Diet, explains why the risk is so high. Dr. Tamiko Katsumoto from Stanford conducted most of the interview. Her background: https://stanfordhealthcare.org/doctors/k/tamiko-katsumoto.html PAPERS: Nature: Optimal dietary patterns for healthy aging https://www.nature.com/articles/s41591-025-03570-5 Fasting mimicking diet cycles versus a Mediterranean diet and cardiometabolic risk in overweight and obese hypertensive subjects: a randomized clinical trial by Valter Longo https://www.nature.com/articles/s44324-023-00002-1 Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population https://www.cell.com/cell-metabolism/fulltext/S1550-4131(14)00062-X Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(18)30135-X/fulltext Dietary Amino Acids and Risk of Stroke Subtypes: Results from 3 Large Prospective Cohort Studies https://www.sciencedirect.com/science/article/pii/S0022316625001786 Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2540540 Dietary protein intake in midlife in relation to healthy aging – results from the prospective Nurses’ Health Study cohort https://www.sciencedirect.com/science/article/pii/S0002916523662823 FILM: Fasting and the Longevity Revolution with Valter Longo (awesome): https://www.fastingandthelongevityrevolution.com/ WEBSITES: All things Dr. Longo — books, a documentary, information https://valterlongo.com/ Fasting Mimicking Diet kits (Prolon): https://prolonlife.com/ The Create Cures Foundation (A Longo foundation): https://createcures.org/ Fondazione Valter Longo https://www.fondazionevalterlongo.org/en/ 0:00 Exc https://www.youtube-nocookie.com/embed/2_sMFBuY3y4 5902 2025-06-21T13:00:09.000Z 2026-10-22T19:32:32.125Z https://longevityharbor.com/de/watch/2_sMFBuY3y4 Why High Protein Diets Could Be Dangerous | Dr. Valter Longo https://i.ytimg.com/vi/2_sMFBuY3y4/hqdefault.jpg Excess protein may dramatically increase the risk of cancer and accelerate aging. Dr. Valter Longo, one of the top scientists in aging research and creator of the Fasting Mimicking Diet, explains why the risk is so high. Dr. Tamiko Katsumoto from Stanford conducted most of the interview. Her background: https://stanfordhealthcare.org/doctors/k/tamiko-katsumoto.html PAPERS: Nature: Optimal dietary patterns for healthy aging https://www.nature.com/articles/s41591-025-03570-5 Fasting mimicking diet cycles versus a Mediterranean diet and cardiometabolic risk in overweight and obese hypertensive subjects: a randomized clinical trial by Valter Longo https://www.nature.com/articles/s44324-023-00002-1 Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population https://www.cell.com/cell-metabolism/fulltext/S1550-4131(14)00062-X Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(18)30135-X/fulltext Dietary Amino Acids and Risk of Stroke Subtypes: Results from 3 Large Prospective Cohort Studies https://www.sciencedirect.com/science/article/pii/S0022316625001786 Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2540540 Dietary protein intake in midlife in relation to healthy aging – results from the prospective Nurses’ Health Study cohort https://www.sciencedirect.com/science/article/pii/S0002916523662823 FILM: Fasting and the Longevity Revolution with Valter Longo (awesome): https://www.fastingandthelongevityrevolution.com/ WEBSITES: All things Dr. Longo — books, a documentary, information https://valterlongo.com/ Fasting Mimicking Diet kits (Prolon): https://prolonlife.com/ The Create Cures Foundation (A Longo foundation): https://createcures.org/ Fondazione Valter Longo https://www.fondazionevalterlongo.org/en/ 0:00 Exc https://www.youtube-nocookie.com/embed/2_sMFBuY3y4 5902 2025-06-21T13:00:09.000Z 2026-10-22T19:32:32.125Z https://longevityharbor.com/en/watch/2d0exG3WkEg Fasting and longevity: Prof. Michalsen on what the hype is worth https://i.ytimg.com/vi/2d0exG3WkEg/hqdefault.jpg In this foodwatch video description, Prof. Dr. Andreas Michalsen is presented as explaining what fasting really does for health, what to pay attention to, and why there are so few studies on the topic. The description does not report his answers. https://www.youtube-nocookie.com/embed/2d0exG3WkEg 1736 2026-09-07T11:28:54.000Z 2026-10-22T22:27:54.316Z https://longevityharbor.com/de/watch/2d0exG3WkEg Fasten und Longevity: Prof. Michalsen zum Hype und was dran ist https://i.ytimg.com/vi/2d0exG3WkEg/hqdefault.jpg In dieser foodwatch-Videobeschreibung wird Prof. Dr. Andreas Michalsen vorgestellt, der erklärt, was Fasten gesundheitlich wirklich bringt, worauf man achten sollte und warum es so wenige Studien dazu gibt. Seine Antworten nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/2d0exG3WkEg 1736 2026-09-07T11:28:54.000Z 2026-10-22T22:27:54.316Z https://longevityharbor.com/en/watch/2iCVKRxsgE0 Fasting is NOT THE SAME as Calorie Restriction (what the science says) https://i.ytimg.com/vi/2iCVKRxsgE0/hqdefault.jpg Use Code THOMASMAY for 20% Off Kettle & Fire: https://www.kf91trk.com/BXCXC4/9B9DM/?sub1=may-youtube Fasting and continuous calorie restriction are constantly being compared to each other. So let's take a look at the similarities and differences between the two and see if one is better than the other! This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Please check out the new workout channel, Garage Built Life, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Fasting is NOT THE SAME as Calorie Restriction (what the science says)- Thomas DeLauer Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857384/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990470/ https://onlinelibrary.wiley.com/doi/10.1111/j.1467-789X.2011.00873.x https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509734/ https://pubmed.ncbi.nlm.nih.gov/22283635/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC303494/pdf/jcinvest00079-0206.pdf https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30429-2 Timestamps ⏱ 0:00 - Intro - Fasting vs Caloric Restriction 0:30 - Fasting is Caloric Restriction 2:33 - If You Fast Everyday... 3:30 - Intermittent vs Daily Energy Restriction 5:38 - Benefits Independent of Weight Loss 7:50 - Intermittent vs Daily Energy Restriction on Muscle Mass 9:48 - Try a Bone Broth Fast 10:05 - Use Code THOMASMAY for 20% Off Kettle & Fire 10:59 - Fasting & Ketones 13:38 - Autophagy 15:33 - How Do They Differ? Which is Better? https://www.youtube-nocookie.com/embed/2iCVKRxsgE0 994 2022-05-04T14:20:08.000Z 2026-10-22T17:43:38.478Z https://longevityharbor.com/de/watch/2iCVKRxsgE0 Fasting is NOT THE SAME as Calorie Restriction (what the science says) https://i.ytimg.com/vi/2iCVKRxsgE0/hqdefault.jpg Use Code THOMASMAY for 20% Off Kettle & Fire: https://www.kf91trk.com/BXCXC4/9B9DM/?sub1=may-youtube Fasting and continuous calorie restriction are constantly being compared to each other. So let's take a look at the similarities and differences between the two and see if one is better than the other! This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Please check out the new workout channel, Garage Built Life, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Fasting is NOT THE SAME as Calorie Restriction (what the science says)- Thomas DeLauer Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857384/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990470/ https://onlinelibrary.wiley.com/doi/10.1111/j.1467-789X.2011.00873.x https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509734/ https://pubmed.ncbi.nlm.nih.gov/22283635/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC303494/pdf/jcinvest00079-0206.pdf https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30429-2 Timestamps ⏱ 0:00 - Intro - Fasting vs Caloric Restriction 0:30 - Fasting is Caloric Restriction 2:33 - If You Fast Everyday... 3:30 - Intermittent vs Daily Energy Restriction 5:38 - Benefits Independent of Weight Loss 7:50 - Intermittent vs Daily Energy Restriction on Muscle Mass 9:48 - Try a Bone Broth Fast 10:05 - Use Code THOMASMAY for 20% Off Kettle & Fire 10:59 - Fasting & Ketones 13:38 - Autophagy 15:33 - How Do They Differ? Which is Better? https://www.youtube-nocookie.com/embed/2iCVKRxsgE0 994 2022-05-04T14:20:08.000Z 2026-10-22T17:43:38.478Z https://longevityharbor.com/en/watch/2lTjPIOXGGk DW documentary description: Mediterranean diet and health claims https://i.ytimg.com/vi/2lTjPIOXGGk/hqdefault.jpg The description says the documentary examines how traditional Mediterranean cuisine, based mainly on plant foods, may affect the body and how foods, combinations and lifestyle may reduce disease risk. It names research centers in six countries; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/2lTjPIOXGGk 2546 2025-12-31T17:00:08.000Z 2026-10-23T03:02:44.930Z https://longevityharbor.com/de/watch/2lTjPIOXGGk DW-Dokumentarbeschreibung: Mittelmeerdiät und Gesundheitsaussagen https://i.ytimg.com/vi/2lTjPIOXGGk/hqdefault.jpg Laut Beschreibung untersucht die Dokumentation, wie sich traditionelle mediterrane Küche, vor allem auf pflanzlichen Lebensmitteln, auf den Körper auswirken kann und wie Lebensmittel, Kombinationen und Lebensstil Krankheitsrisiken senken könnten. Sie nennt Forschungszentren in sechs Ländern; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/2lTjPIOXGGk 2546 2025-12-31T17:00:08.000Z 2026-10-23T03:02:44.930Z https://longevityharbor.com/en/watch/2lmHrII0MzI Der Fasten- & Ernährung-Experte! Prof. Dr. Andreas Michalsen (staYoung - Der Longevity-Podcast #2) https://i.ytimg.com/vi/2lmHrII0MzI/hqdefault.jpg In dieser längeren Folge hörst du von einer echten Koryphäe. Prof. Dr. med. Andreas Michalsen ist Chefarzt für Innere Medizin und gleichzeitig Chefarzt für Naturheilkunde. Er arbeitet in Berlin an der Charité und am Immanuel Krankenhaus. Tauche ein in die Welt von Prof. Michalsen: Fasten & Kalorienreduktion Zucker (Glucose, Fructose & Saccharose) Tiefkühlprodukte Vegane Ersatzprodukte Arsen im Reis Proteine & Fette Bio-Produkte Polyphenole Fermentierte Lebensmittel ... und vieles mehr. Hinterlasse eine Bewertung für diesen Podcast, wenn er dir gefallen hat und teile diese Folge mit Freunden via Whatsapp oder Telegram. Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen, wende dich bitte an deinen Arzt/deine Ärztin. https://www.youtube-nocookie.com/embed/2lmHrII0MzI 3173 2024-02-16T05:00:09.000Z 2026-10-22T17:43:37.672Z https://longevityharbor.com/de/watch/2lmHrII0MzI Der Fasten- & Ernährung-Experte! Prof. Dr. Andreas Michalsen (staYoung - Der Longevity-Podcast #2) https://i.ytimg.com/vi/2lmHrII0MzI/hqdefault.jpg In dieser längeren Folge hörst du von einer echten Koryphäe. Prof. Dr. med. Andreas Michalsen ist Chefarzt für Innere Medizin und gleichzeitig Chefarzt für Naturheilkunde. Er arbeitet in Berlin an der Charité und am Immanuel Krankenhaus. Tauche ein in die Welt von Prof. Michalsen: Fasten & Kalorienreduktion Zucker (Glucose, Fructose & Saccharose) Tiefkühlprodukte Vegane Ersatzprodukte Arsen im Reis Proteine & Fette Bio-Produkte Polyphenole Fermentierte Lebensmittel ... und vieles mehr. Hinterlasse eine Bewertung für diesen Podcast, wenn er dir gefallen hat und teile diese Folge mit Freunden via Whatsapp oder Telegram. Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen, wende dich bitte an deinen Arzt/deine Ärztin. https://www.youtube-nocookie.com/embed/2lmHrII0MzI 3173 2024-02-16T05:00:09.000Z 2026-10-22T17:43:37.672Z https://longevityharbor.com/en/watch/2nqvJ8cn5Fg Behind the Study: Longevity Biotechnology - AI, Biomarkers, Geroscience for Healthy Aging | Aging-US https://i.ytimg.com/vi/2nqvJ8cn5Fg/hqdefault.jpg Drs. Alex Zhavoronkov, Morten Scheibye-Knudsen, Evelyne Bischof and Dominika Wilczok discuss a #research paper they co-authored that was #published as the #cover of Aging (Aging-US) Volume 16, Issue 20, entitled, “Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.” @ardd3628 #authors #interview #authorinterview #researchers #aging #biotechnology #ai #artificialintelligence #longevity #healthspan #lifespan #openaccess #openscience #peerreview #journal #publication #publishing #meded DOI - https://doi.org/10.18632/aging.206135 Corresponding Authors - Yu-Xuan Lyu - lvyx@sustech.edu.cn, Alex Zhavoronkov - alex@insilico.com, Morten Scheibye-Knudsen - mscheibye@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk Video transcription - https://www.aging-us.com/interviews/longevity-biotechnology-ai-biomarkers-geroscience-for-healthy-aging Video short - https://www.youtube.com/watch?v=Hpfe5WJ5g7I Abstract The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We, from the gathering at the Aging Research and Drug Discovery Meeting in 2023, summarised the latest developments in healthspan biotechnology, with a particular emphasis on artificial intelligence (AI), biomarkers and clocks, geroscience, and clinical trials and interventions for healthy longevity. Moreover, we provide an overview of academic research and the biotech industry focused on targeting ageing as the root of age-related diseases to combat multimorbidity and extend healthspan. We propose that the integration of generative AI, cutting-edge biological technology, and longevity medicine is essential for extending the productive and healthy human lifespan. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206135 Subscribe for free publication alerts from Aging - http https://www.youtube-nocookie.com/embed/2nqvJ8cn5Fg 1000 2024-11-21T15:45:43.000Z 2026-10-22T19:04:38.782Z https://longevityharbor.com/de/watch/2nqvJ8cn5Fg Behind the Study: Longevity Biotechnology - AI, Biomarkers, Geroscience for Healthy Aging | Aging-US https://i.ytimg.com/vi/2nqvJ8cn5Fg/hqdefault.jpg Drs. Alex Zhavoronkov, Morten Scheibye-Knudsen, Evelyne Bischof and Dominika Wilczok discuss a #research paper they co-authored that was #published as the #cover of Aging (Aging-US) Volume 16, Issue 20, entitled, “Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.” @ardd3628 #authors #interview #authorinterview #researchers #aging #biotechnology #ai #artificialintelligence #longevity #healthspan #lifespan #openaccess #openscience #peerreview #journal #publication #publishing #meded DOI - https://doi.org/10.18632/aging.206135 Corresponding Authors - Yu-Xuan Lyu - lvyx@sustech.edu.cn, Alex Zhavoronkov - alex@insilico.com, Morten Scheibye-Knudsen - mscheibye@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk Video transcription - https://www.aging-us.com/interviews/longevity-biotechnology-ai-biomarkers-geroscience-for-healthy-aging Video short - https://www.youtube.com/watch?v=Hpfe5WJ5g7I Abstract The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We, from the gathering at the Aging Research and Drug Discovery Meeting in 2023, summarised the latest developments in healthspan biotechnology, with a particular emphasis on artificial intelligence (AI), biomarkers and clocks, geroscience, and clinical trials and interventions for healthy longevity. Moreover, we provide an overview of academic research and the biotech industry focused on targeting ageing as the root of age-related diseases to combat multimorbidity and extend healthspan. We propose that the integration of generative AI, cutting-edge biological technology, and longevity medicine is essential for extending the productive and healthy human lifespan. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206135 Subscribe for free publication alerts from Aging - http https://www.youtube-nocookie.com/embed/2nqvJ8cn5Fg 1000 2024-11-21T15:45:43.000Z 2026-10-22T19:04:38.782Z https://longevityharbor.com/en/watch/2uqy9izxe3k Metabolism, Fasting, and Strength Training: The Latest in Longevity https://i.ytimg.com/vi/2uqy9izxe3k/hqdefault.jpg Get ready to discover the ultimate blueprint for staying youthful, fit, and energised! https://www.youtube-nocookie.com/embed/2uqy9izxe3k 3700 2025-02-20T10:23:13.000Z 2026-10-22T19:32:30.815Z https://longevityharbor.com/de/watch/2uqy9izxe3k Metabolism, Fasting, and Strength Training: The Latest in Longevity https://i.ytimg.com/vi/2uqy9izxe3k/hqdefault.jpg Get ready to discover the ultimate blueprint for staying youthful, fit, and energised! https://www.youtube-nocookie.com/embed/2uqy9izxe3k 3700 2025-02-20T10:23:13.000Z 2026-10-22T19:32:30.815Z https://longevityharbor.com/en/watch/2xR7q_t2WSo 9 Signs You’re Aging Too Fast & How to Reverse Them https://i.ytimg.com/vi/2xR7q_t2WSo/hqdefault.jpg We’ve been told aging is inevitable, but what if you could slow it down? In this episode, Dr. Josh Axe unpacks the latest science on how lifestyle, not just genetics, shapes how long (and how well) we live. From Blue Zones eating habits to ancient herbal wisdom, you’ll learn practical, research-backed steps to protect your body at the cellular level, boost energy, and add healthy years to your life. In this episode, you’ll discover: * The 9 “hallmarks of aging” and how to address each one naturally * What Blue Zone cultures eat (and do) to live past 100 * Herbs and supplements that help fight inflammation, protect mitochondria, and support longevity * The role of gut health in slowing aging * Simple daily habits that can add years to your life—without extreme diets or workouts #longevityhacks #agingwell #healthyhabits #wellnesstips #antiinflammatory #superfoods #nutritionalhealing #healthylivingtips #wellnesslifestyle #drjoshaxe -------------------- 0:00 Introduction 2:35 Aging starts in your cells 3:29 Altered cellular communication 5:12 Microbiome dysbiosis 7:12 Epigenetic imbalances 10:46 Mitochondrial dysfunction 13:42 Oxidative stress 15:48 Inflammaging 18:35 Impaired autophagy 21:33 Cellular senescence 24:36 Stem cell exhaustion 26:47 Bloodwork ad 27:40 3 treasures of longevity 31:11 #1 Body 31:39 #2 Energy 35:30 Blue Zone diets and "Power 9" 42:07 Exercise + Pickelball 45:15 Top herbs and supplements for longevity 49:00 Longevity -------------------- Links: https://pubmed.ncbi.nlm.nih.gov/8786073/ https://www.bluezones.com/2016/11/power-9/ https://www.americashealthrankings.org/learn/reports/2016-annual-report/comparison-with-other-nations https://www.commonwealthfund.org/blog/2022/americans-no-matter-state-they-live-die-younger-people-many-other-countries https://pmc.ncbi.nlm.nih.gov/articles/PMC6125071/ https://path-of-dao-qigong.ch/en/jing-qi-shen/ https://threetreasurestcm.com/jing-qi-shen/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3836174/ https://www.sciencedirect.com/science/arti https://www.youtube-nocookie.com/embed/2xR7q_t2WSo 3073 2025-08-11T16:00:05.000Z 2026-10-22T19:04:37.517Z https://longevityharbor.com/de/watch/2xR7q_t2WSo 9 Signs You’re Aging Too Fast & How to Reverse Them https://i.ytimg.com/vi/2xR7q_t2WSo/hqdefault.jpg We’ve been told aging is inevitable, but what if you could slow it down? In this episode, Dr. Josh Axe unpacks the latest science on how lifestyle, not just genetics, shapes how long (and how well) we live. From Blue Zones eating habits to ancient herbal wisdom, you’ll learn practical, research-backed steps to protect your body at the cellular level, boost energy, and add healthy years to your life. In this episode, you’ll discover: * The 9 “hallmarks of aging” and how to address each one naturally * What Blue Zone cultures eat (and do) to live past 100 * Herbs and supplements that help fight inflammation, protect mitochondria, and support longevity * The role of gut health in slowing aging * Simple daily habits that can add years to your life—without extreme diets or workouts #longevityhacks #agingwell #healthyhabits #wellnesstips #antiinflammatory #superfoods #nutritionalhealing #healthylivingtips #wellnesslifestyle #drjoshaxe -------------------- 0:00 Introduction 2:35 Aging starts in your cells 3:29 Altered cellular communication 5:12 Microbiome dysbiosis 7:12 Epigenetic imbalances 10:46 Mitochondrial dysfunction 13:42 Oxidative stress 15:48 Inflammaging 18:35 Impaired autophagy 21:33 Cellular senescence 24:36 Stem cell exhaustion 26:47 Bloodwork ad 27:40 3 treasures of longevity 31:11 #1 Body 31:39 #2 Energy 35:30 Blue Zone diets and "Power 9" 42:07 Exercise + Pickelball 45:15 Top herbs and supplements for longevity 49:00 Longevity -------------------- Links: https://pubmed.ncbi.nlm.nih.gov/8786073/ https://www.bluezones.com/2016/11/power-9/ https://www.americashealthrankings.org/learn/reports/2016-annual-report/comparison-with-other-nations https://www.commonwealthfund.org/blog/2022/americans-no-matter-state-they-live-die-younger-people-many-other-countries https://pmc.ncbi.nlm.nih.gov/articles/PMC6125071/ https://path-of-dao-qigong.ch/en/jing-qi-shen/ https://threetreasurestcm.com/jing-qi-shen/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3836174/ https://www.sciencedirect.com/science/arti https://www.youtube-nocookie.com/embed/2xR7q_t2WSo 3073 2025-08-11T16:00:05.000Z 2026-10-22T19:04:37.517Z https://longevityharbor.com/en/watch/2zAg0DPhrs0 Dudley Lamming: mTOR – How Dietary Protein and Amino Acids Affect Aging and Disease Processes https://i.ytimg.com/vi/2zAg0DPhrs0/hqdefault.jpg Research has shown that excessive dietary protein intake and high amounts of branch-chain amino acids (BCAA) in particular can accelerate aging and exacerbate chronic diseases of aging. In this episode University of Wisconsin Assoc. Professor Dudley Lamming talks about the cellular amino acid sensing mTOR pathway and its influences on aging and disease processes. The Lamming laboratory is making major contributions to establishing how amino acid intake affects cells and organ systems in health and disease. This research has important implications for optimizing health throughout the lifespan. LINKS Lamming lab webpage: https://lamminglab.medicine.wisc.edu/ Review article: https://pmc.ncbi.nlm.nih.gov/articles/PMC9197406/pdf/ACEL-21-e13626.pdf Protein restriction in Alzheimer’s mouse model: https://pmc.ncbi.nlm.nih.gov/articles/PMC11189507/pdf/41467_2024_Article_49589.pdf BCAA restriction, aging, and lifespan: https://pmc.ncbi.nlm.nih.gov/articles/PMC10655617/pdf/nihms-1939504.pdf https://www.youtube-nocookie.com/embed/2zAg0DPhrs0 4537 2025-03-11T12:46:24.000Z 2026-10-22T19:04:40.700Z https://longevityharbor.com/de/watch/2zAg0DPhrs0 Dudley Lamming: mTOR – How Dietary Protein and Amino Acids Affect Aging and Disease Processes https://i.ytimg.com/vi/2zAg0DPhrs0/hqdefault.jpg Research has shown that excessive dietary protein intake and high amounts of branch-chain amino acids (BCAA) in particular can accelerate aging and exacerbate chronic diseases of aging. In this episode University of Wisconsin Assoc. Professor Dudley Lamming talks about the cellular amino acid sensing mTOR pathway and its influences on aging and disease processes. The Lamming laboratory is making major contributions to establishing how amino acid intake affects cells and organ systems in health and disease. This research has important implications for optimizing health throughout the lifespan. LINKS Lamming lab webpage: https://lamminglab.medicine.wisc.edu/ Review article: https://pmc.ncbi.nlm.nih.gov/articles/PMC9197406/pdf/ACEL-21-e13626.pdf Protein restriction in Alzheimer’s mouse model: https://pmc.ncbi.nlm.nih.gov/articles/PMC11189507/pdf/41467_2024_Article_49589.pdf BCAA restriction, aging, and lifespan: https://pmc.ncbi.nlm.nih.gov/articles/PMC10655617/pdf/nihms-1939504.pdf https://www.youtube-nocookie.com/embed/2zAg0DPhrs0 4537 2025-03-11T12:46:24.000Z 2026-10-22T19:04:40.700Z https://longevityharbor.com/en/watch/33-CAAztikU Video description: senolytics, FOXO4-DRI and mTOR explained by a PhD scientist https://i.ytimg.com/vi/33-CAAztikU/hqdefault.jpg According to the description, the creator, a PhD scientist studying cellular biology, explains senescence, senolytics, autophagy, mitophagy and mTOR, and says she is personally waiting on the FOXO4-DRI peptide until human clinical data exist because it is currently supported mainly by mouse data. https://www.youtube-nocookie.com/embed/33-CAAztikU 1215 2026-03-15T13:30:04.000Z 2026-10-23T02:05:52.531Z https://longevityharbor.com/de/watch/33-CAAztikU Videobeschreibung: Senolytika, FOXO4-DRI und mTOR, erklärt von einer PhD-Wissenschaftlerin https://i.ytimg.com/vi/33-CAAztikU/hqdefault.jpg Laut Beschreibung erklärt die Erstellerin, eine PhD-Wissenschaftlerin, die Zellbiologie untersucht, Seneszenz, Senolytika, Autophagie, Mitophagie und mTOR; sie persönlich wartet beim Peptid FOXO4-DRI auf humane klinische Daten, da es derzeit vor allem durch Mausdaten gestützt sei. https://www.youtube-nocookie.com/embed/33-CAAztikU 1215 2026-03-15T13:30:04.000Z 2026-10-23T02:05:52.531Z https://longevityharbor.com/en/watch/34cNHqVb9fc Circadian Rhythms in Muscle Cells: Impact of Disruption on Aging and Metabolism https://i.ytimg.com/vi/34cNHqVb9fc/hqdefault.jpg This podcast episode explores the role of circadian rhythms in muscle health and metabolism, discussing how internal clocks within muscle cells influence aging, energy management, and recovery. It covers the impact of disrupted rhythms on muscle function, insulin resistance, and metabolic flexibility, while also highlighting potential interventions like chrono-nutrition and timed exercise. https://gfunfacts.online/article/ea5e51eb-5d52-43e9-8fba-54251a1b6771.html https://www.youtube-nocookie.com/embed/34cNHqVb9fc 500 2025-06-06T02:09:34.000Z 2026-10-22T19:21:25.296Z https://longevityharbor.com/de/watch/34cNHqVb9fc Circadian Rhythms in Muscle Cells: Impact of Disruption on Aging and Metabolism https://i.ytimg.com/vi/34cNHqVb9fc/hqdefault.jpg This podcast episode explores the role of circadian rhythms in muscle health and metabolism, discussing how internal clocks within muscle cells influence aging, energy management, and recovery. It covers the impact of disrupted rhythms on muscle function, insulin resistance, and metabolic flexibility, while also highlighting potential interventions like chrono-nutrition and timed exercise. https://gfunfacts.online/article/ea5e51eb-5d52-43e9-8fba-54251a1b6771.html https://www.youtube-nocookie.com/embed/34cNHqVb9fc 500 2025-06-06T02:09:34.000Z 2026-10-22T19:21:25.296Z https://longevityharbor.com/en/watch/3CnKnIXKDoE Peptides and Longevity: What the Lifespan Episode Description Says https://i.ytimg.com/vi/3CnKnIXKDoE/hqdefault.jpg The description says David and Matt discuss peptides such as GHK-Cu, MOTS-c, Epitalon and apelin and what research suggests about cellular repair, stem cells, telomeres and hallmarks of aging. It says David separates promising treatments from unproven hype and covers possible benefits, risks and open questions. https://www.youtube-nocookie.com/embed/3CnKnIXKDoE 3363 2026-10-18T17:00:37.000Z 2026-10-22T19:57:31.751Z https://longevityharbor.com/de/watch/3CnKnIXKDoE Peptide und Langlebigkeit: Was die Lifespan-Episodenbeschreibung sagt https://i.ytimg.com/vi/3CnKnIXKDoE/hqdefault.jpg Laut Beschreibung sprechen David und Matt über Peptide wie GHK-Cu, MOTS-c, Epitalon und Apelin und darüber, was die Forschung zu Zellreparatur, Stammzellen, Telomeren und Hallmarks des Alterns nahelegt. David trenne vielversprechende Ansätze von unbelegtem Hype und behandle mögliche Nutzen, Risiken und offene Fragen. https://www.youtube-nocookie.com/embed/3CnKnIXKDoE 3363 2026-10-18T17:00:37.000Z 2026-10-22T19:57:31.751Z https://longevityharbor.com/en/watch/3FC1j4PG1O0 Rapamycin for Longevity? The Anti-Aging Drug Backed by Science | Doctors Group Australia https://i.ytimg.com/vi/3FC1j4PG1O0/hqdefault.jpg Can a drug from Easter Island slow aging and extend life? In this video, we explore the growing science behind Rapamycin — a compound originally used in organ transplants that is now being studied for its powerful anti-aging effects. Backed by exciting research, Rapamycin works by inhibiting the mTOR pathway, triggering the body’s repair systems and promoting cellular rejuvenation. 🧬 What we’ll cover: What Rapamycin is and how it works How it supports autophagy (your body’s cellular cleanup system) Findings from animal studies showing extended lifespan and improved organ function New human clinical trials (2024) exploring its role in immune aging, inflammation, and longevity Potential benefits for brain health, cancer prevention, and age-related diseases Cautions, side effects, and why intermittent, low-dose use is key At Doctors Group – Longevity Organic, we explore the intersection of modern science and clean living — sharing powerful wellness tools backed by global research. 📍Based in Australia | Clean. Natural. Science-Backed. 🎯 Subscribe for weekly longevity videos 📲 Follow us on Instagram: @doctorsgroupofficial 🌐 Learn more at www.doctorsgroup.au ⚠️ Medical Disclaimer : Disclaimer: This video is for informational and educational purposes only and does not constitute medical advice. Rapamycin is a prescription-only medication that is not approved for anti-aging use in Australia or most countries. Always consult a licensed medical professional before starting any new medication or treatment. Content is based on publicly available research and is not a substitute for professional healthcare guidance. This content is intended for educational purposes only. Rapamycin is a prescription-only medication and not approved for anti-aging use in Australia. Always consult with a qualified medical professional before using any medication or starting a new treatment. https://www.youtube-nocookie.com/embed/3FC1j4PG1O0 198 2025-06-25T04:03:33.000Z 2026-10-22T19:04:40.798Z https://longevityharbor.com/de/watch/3FC1j4PG1O0 Rapamycin for Longevity? The Anti-Aging Drug Backed by Science | Doctors Group Australia https://i.ytimg.com/vi/3FC1j4PG1O0/hqdefault.jpg Can a drug from Easter Island slow aging and extend life? In this video, we explore the growing science behind Rapamycin — a compound originally used in organ transplants that is now being studied for its powerful anti-aging effects. Backed by exciting research, Rapamycin works by inhibiting the mTOR pathway, triggering the body’s repair systems and promoting cellular rejuvenation. 🧬 What we’ll cover: What Rapamycin is and how it works How it supports autophagy (your body’s cellular cleanup system) Findings from animal studies showing extended lifespan and improved organ function New human clinical trials (2024) exploring its role in immune aging, inflammation, and longevity Potential benefits for brain health, cancer prevention, and age-related diseases Cautions, side effects, and why intermittent, low-dose use is key At Doctors Group – Longevity Organic, we explore the intersection of modern science and clean living — sharing powerful wellness tools backed by global research. 📍Based in Australia | Clean. Natural. Science-Backed. 🎯 Subscribe for weekly longevity videos 📲 Follow us on Instagram: @doctorsgroupofficial 🌐 Learn more at www.doctorsgroup.au ⚠️ Medical Disclaimer : Disclaimer: This video is for informational and educational purposes only and does not constitute medical advice. Rapamycin is a prescription-only medication that is not approved for anti-aging use in Australia or most countries. Always consult a licensed medical professional before starting any new medication or treatment. Content is based on publicly available research and is not a substitute for professional healthcare guidance. This content is intended for educational purposes only. Rapamycin is a prescription-only medication and not approved for anti-aging use in Australia. Always consult with a qualified medical professional before using any medication or starting a new treatment. https://www.youtube-nocookie.com/embed/3FC1j4PG1O0 198 2025-06-25T04:03:33.000Z 2026-10-22T19:04:40.798Z https://longevityharbor.com/en/watch/3FkCbvcoL7A Podcast interview on menopause, hormones, energy and healthy ageing for women over 40 https://i.ytimg.com/vi/3FkCbvcoL7A/hqdefault.jpg In this podcast description, Ralph Steuernagel, described as an expert in hormonal health with almost 30 years of practice, talks with Katherina Bock about how menopause is experienced, why exhaustion is described as common, and the roles of sleep, movement and breathing. The description says the video avoids unrealistic promises. https://www.youtube-nocookie.com/embed/3FkCbvcoL7A 5166 2026-04-03T07:00:05.000Z 2026-10-23T01:45:43.837Z https://longevityharbor.com/de/watch/3FkCbvcoL7A Podcast-Interview zu Wechseljahren, Hormonen, Energie und gesundem Altern für Frauen Ü40 https://i.ytimg.com/vi/3FkCbvcoL7A/hqdefault.jpg In dieser Podcast-Beschreibung spricht Ralph Steuernagel, bezeichnet als Experte für hormonelle Gesundheit mit fast 30 Jahren Praxisarbeit, mit Katherina Bock darüber, wie die Wechseljahre erlebt werden, warum Erschöpfung als häufig beschrieben wird und welche Rolle Schlaf, Bewegung und Atmung spielen. Laut Beschreibung verzichtet das Video auf unrealistische Versprechen. https://www.youtube-nocookie.com/embed/3FkCbvcoL7A 5166 2026-04-03T07:00:05.000Z 2026-10-23T01:45:43.837Z https://longevityharbor.com/en/watch/3InuvdIsfyQ Podcast on inflammaging in arthritis, brain injury and critical illness https://i.ytimg.com/vi/3InuvdIsfyQ/hqdefault.jpg In this GeriPal podcast description, three researchers discuss inflammaging, described as chronic progressive low-grade inflammation with aging, and how it relates to rheumatologic, neurologic and critical-illness conditions. https://www.youtube-nocookie.com/embed/3InuvdIsfyQ 3028 2025-12-03T23:07:25.000Z 2026-10-23T03:22:23.363Z https://longevityharbor.com/de/watch/3InuvdIsfyQ Podcast zu Inflammaging bei Arthritis, Hirnverletzung und kritischer Krankheit https://i.ytimg.com/vi/3InuvdIsfyQ/hqdefault.jpg In dieser GeriPal-Podcastbeschreibung sprechen drei Forschende über Inflammaging, beschrieben als chronische fortschreitende niedriggradige Entzündung beim Altern, und dessen Bezug zu rheumatologischen, neurologischen und kritisch-kranken Erkrankungen. https://www.youtube-nocookie.com/embed/3InuvdIsfyQ 3028 2025-12-03T23:07:25.000Z 2026-10-23T03:22:23.363Z https://longevityharbor.com/en/watch/3J2-tdvUxJA Anti-Aging-Forschung: Sind Senolytika der Schlüssel zu einem längeren Leben? https://i.ytimg.com/vi/3J2-tdvUxJA/hqdefault.jpg Die Entwicklung sogenannter Senolytika ist eines der derzeit spannendsten Themen der Anti-Aging-Forschung. Aber was versteht man darunter? Senolytika sollen seneszente Zellen, man spricht auch von Zombie-Zellen, endgültig unschädlich machen. Gelänge es, ein entsprechendes Medikament zu entwickeln, ließe sich die Lebenserwartung deutlich steigern. Und zumindest in Laborversuchen zeigen Senolytika bereits herausragende Ergebnisse. Aber warum sind seneszente Zellen so gefährlich und was haben faule Äpfel damit zu tun? Wir klären auf! Hier findest du den Science Proof: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610675/ Professor Bernd Kleine-Gunk ist renommierter Buchautor und Präsident der German Society of Anti-Aging-Medicine. Er beschäftigt sich seit Jahren mit den Themen Anti-Aging, Lebensverlängerung, Fitness und Gesundheitsoptimierung. Like "Für immer jung mit Kleine-Gunk" bei Facebook: https://www.facebook.com/F%C3%BCr-immer-jung-mit-Kleine-Gunk-106299400758644/ Abonniere "Für immer jung mit Kleine-Gunk": https://www.youtube.com/channel/UCb34TcCb6AFZhZ9LGtUmSoA Bild-Credits: Zombie: DoomSlayer/Pixabay Maus: Clker-Free-Vector-Images/Pixabay https://www.youtube-nocookie.com/embed/3J2-tdvUxJA 518 2020-07-24T05:00:01.000Z 2026-10-23T02:24:27.174Z https://longevityharbor.com/de/watch/3J2-tdvUxJA Anti-Aging-Forschung: Sind Senolytika der Schlüssel zu einem längeren Leben? https://i.ytimg.com/vi/3J2-tdvUxJA/hqdefault.jpg Die Entwicklung sogenannter Senolytika ist eines der derzeit spannendsten Themen der Anti-Aging-Forschung. Aber was versteht man darunter? Senolytika sollen seneszente Zellen, man spricht auch von Zombie-Zellen, endgültig unschädlich machen. Gelänge es, ein entsprechendes Medikament zu entwickeln, ließe sich die Lebenserwartung deutlich steigern. Und zumindest in Laborversuchen zeigen Senolytika bereits herausragende Ergebnisse. Aber warum sind seneszente Zellen so gefährlich und was haben faule Äpfel damit zu tun? Wir klären auf! Hier findest du den Science Proof: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610675/ Professor Bernd Kleine-Gunk ist renommierter Buchautor und Präsident der German Society of Anti-Aging-Medicine. Er beschäftigt sich seit Jahren mit den Themen Anti-Aging, Lebensverlängerung, Fitness und Gesundheitsoptimierung. Like "Für immer jung mit Kleine-Gunk" bei Facebook: https://www.facebook.com/F%C3%BCr-immer-jung-mit-Kleine-Gunk-106299400758644/ Abonniere "Für immer jung mit Kleine-Gunk": https://www.youtube.com/channel/UCb34TcCb6AFZhZ9LGtUmSoA Bild-Credits: Zombie: DoomSlayer/Pixabay Maus: Clker-Free-Vector-Images/Pixabay https://www.youtube-nocookie.com/embed/3J2-tdvUxJA 518 2020-07-24T05:00:01.000Z 2026-10-23T02:24:27.174Z https://longevityharbor.com/en/watch/3TzvSL8aliY Lab Med and Pathology Research & Discovery Seminar | Matt Kaeberlein https://i.ytimg.com/vi/3TzvSL8aliY/hqdefault.jpg Lab Med and Pathology Research & Discovery Seminar: Matt Kaeberlein - Toward clinical evaluation of rapamycin to target biological aging Toward clinical evaluation of rapamycin to target biological aging Matt Kaeberlein, PhD Professor, Director, Healthy Aging & Longevity Research Institute Director, Nathan Shock Center of Excellence in The Basic Biology of Aging Director, Biological Mechanisms of Healthy Aging Training Program Co-Director, Dog Aging Project Department of Laboratory Medicine & Pathology University of Washington Why Attend this Seminar? The mTOR inhibitor rapamycin is the most robust and reproducible pharmacological intervention to increase lifespan and healthspan metrics in laboratory animals. Several groups have independently shown that short-term treatment with rapamycin during middle-age in mice can prevent age-related decline or rejuvenate functional measures of health in various organs and tissues including brain, heart, kidney, muscle, oral cavity, immune system, and ovary. Here I will summarize the preclinical evidence that rapamycin can positively modulate biological aging and describe current efforts to determine whether these effects are shared in companion dogs and people. Chapters: 0:00 - Introduction by Dr. Alexander Mendenhall 1:01 - Dr. Kaeberlein's Presentation 59:30 - Q&A https://www.youtube-nocookie.com/embed/3TzvSL8aliY 5353 2023-03-09T22:39:26.000Z 2026-10-22T17:43:41.787Z https://longevityharbor.com/de/watch/3TzvSL8aliY Lab Med and Pathology Research & Discovery Seminar | Matt Kaeberlein https://i.ytimg.com/vi/3TzvSL8aliY/hqdefault.jpg Lab Med and Pathology Research & Discovery Seminar: Matt Kaeberlein - Toward clinical evaluation of rapamycin to target biological aging Toward clinical evaluation of rapamycin to target biological aging Matt Kaeberlein, PhD Professor, Director, Healthy Aging & Longevity Research Institute Director, Nathan Shock Center of Excellence in The Basic Biology of Aging Director, Biological Mechanisms of Healthy Aging Training Program Co-Director, Dog Aging Project Department of Laboratory Medicine & Pathology University of Washington Why Attend this Seminar? The mTOR inhibitor rapamycin is the most robust and reproducible pharmacological intervention to increase lifespan and healthspan metrics in laboratory animals. Several groups have independently shown that short-term treatment with rapamycin during middle-age in mice can prevent age-related decline or rejuvenate functional measures of health in various organs and tissues including brain, heart, kidney, muscle, oral cavity, immune system, and ovary. Here I will summarize the preclinical evidence that rapamycin can positively modulate biological aging and describe current efforts to determine whether these effects are shared in companion dogs and people. Chapters: 0:00 - Introduction by Dr. Alexander Mendenhall 1:01 - Dr. Kaeberlein's Presentation 59:30 - Q&A https://www.youtube-nocookie.com/embed/3TzvSL8aliY 5353 2023-03-09T22:39:26.000Z 2026-10-22T17:43:41.787Z https://longevityharbor.com/en/watch/3dYwMfWsnuU NIH Common Fund Cellular Senescence Network (SenNet) Program https://i.ytimg.com/vi/3dYwMfWsnuU/hqdefault.jpg For more information on the Cellular Senescence Network (SenNet) program, visit our website at: https://commonfund.nih.gov/senescence A cell dividing into two cells is a hallmark of human development. Over time, our bodies accumulate a small number of cells that no longer divide. These “senescent” cells are a rare type of cells that play both positive and negative roles in biological processes, either directly or through the release of molecules that affect neighboring cells. The rarity and diversity of these cells previously made them difficult to identify and study, but recent advances in studying individual cells, or single-cell analysis, now make it possible. Therapeutics called “senolytics” are being developed to target senescent cells and remove them from the body, however a deeper understanding of cellular senescence is needed to ensure therapies like senolytics encourage the beneficial effects of senescent cells while suppressing their tissue-damaging effects. For this reason, the Common Fund’s Cellular Senescence Network (SenNet) program was established to comprehensively identify and characterize the differences in senescent cells across the body, across various states of human health, and across the lifespan. SenNet will develop innovative tools and technologies for the study of senescent cells and provide publicly accessible maps and atlases of senescent cells. These data and resources would otherwise be difficult to achieve through individual efforts, and will accelerate the ability of biomedical researchers to develop therapeutics that target cellular senescence and improve human health. https://www.youtube-nocookie.com/embed/3dYwMfWsnuU 183 2023-11-14T14:02:24.000Z 2026-10-22T18:43:13.536Z https://longevityharbor.com/de/watch/3dYwMfWsnuU NIH Common Fund Cellular Senescence Network (SenNet) Program https://i.ytimg.com/vi/3dYwMfWsnuU/hqdefault.jpg For more information on the Cellular Senescence Network (SenNet) program, visit our website at: https://commonfund.nih.gov/senescence A cell dividing into two cells is a hallmark of human development. Over time, our bodies accumulate a small number of cells that no longer divide. These “senescent” cells are a rare type of cells that play both positive and negative roles in biological processes, either directly or through the release of molecules that affect neighboring cells. The rarity and diversity of these cells previously made them difficult to identify and study, but recent advances in studying individual cells, or single-cell analysis, now make it possible. Therapeutics called “senolytics” are being developed to target senescent cells and remove them from the body, however a deeper understanding of cellular senescence is needed to ensure therapies like senolytics encourage the beneficial effects of senescent cells while suppressing their tissue-damaging effects. For this reason, the Common Fund’s Cellular Senescence Network (SenNet) program was established to comprehensively identify and characterize the differences in senescent cells across the body, across various states of human health, and across the lifespan. SenNet will develop innovative tools and technologies for the study of senescent cells and provide publicly accessible maps and atlases of senescent cells. These data and resources would otherwise be difficult to achieve through individual efforts, and will accelerate the ability of biomedical researchers to develop therapeutics that target cellular senescence and improve human health. https://www.youtube-nocookie.com/embed/3dYwMfWsnuU 183 2023-11-14T14:02:24.000Z 2026-10-22T18:43:13.536Z https://longevityharbor.com/en/watch/3dhjjoEgvN4 Horvath: epigenetic clocks as proposed tools for precision medicine https://i.ytimg.com/vi/3dhjjoEgvN4/hqdefault.jpg In this video description, Steve Horvath discusses how epigenetic clocks based on DNA methylation could measure biological age and support precision medicine; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/3dhjjoEgvN4 1590 2026-08-08T08:43:49.000Z 2026-10-22T23:09:07.557Z https://longevityharbor.com/de/watch/3dhjjoEgvN4 Horvath: epigenetische Uhren als vorgeschlagene Werkzeuge der Präzisionsmedizin https://i.ytimg.com/vi/3dhjjoEgvN4/hqdefault.jpg In dieser Videobeschreibung erläutert Steve Horvath, wie epigenetische Uhren auf Basis von DNA-Methylierung biologisches Alter messen und Präzisionsmedizin unterstützen könnten; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/3dhjjoEgvN4 1590 2026-08-08T08:43:49.000Z 2026-10-22T23:09:07.557Z https://longevityharbor.com/en/watch/3qPSFNT--Ts Podcast on biological age tests: epigenetics, proteomics and their interpretation https://i.ytimg.com/vi/3qPSFNT--Ts/hqdefault.jpg In this podcast episode, a guest who developed the proteomic platform behind MOLEQLAR Analytics discusses what biological age means, how it differs from chronological age, and which test approaches exist; the description says different tests often give different results and that longitudinal tracking matters more than a single measurement. https://www.youtube-nocookie.com/embed/3qPSFNT--Ts 4010 2026-04-09T05:00:02.000Z 2026-10-23T01:37:46.278Z https://longevityharbor.com/de/watch/3qPSFNT--Ts Podcast zu biologischen Alterstests: Epigenetik, Proteomik und ihre Einordnung https://i.ytimg.com/vi/3qPSFNT--Ts/hqdefault.jpg In dieser Podcast-Folge spricht ein Gast, der die proteomische Plattform hinter MOLEQLAR Analytics entwickelte, darüber, was biologisches Alter bedeutet, wie es sich vom chronologischen Alter unterscheidet und welche Testverfahren es gibt; laut Beschreibung liefern verschiedene Tests oft unterschiedliche Ergebnisse und longitudinales Tracking sei wichtiger als ein einzelner Messwert. https://www.youtube-nocookie.com/embed/3qPSFNT--Ts 4010 2026-04-09T05:00:02.000Z 2026-10-23T01:37:46.278Z https://longevityharbor.com/en/watch/3qvlKdJgMUM Overview of Longevity Sciences | Davos In The Desert | Longevity Science Conference 2024 #stemcell https://i.ytimg.com/vi/3qvlKdJgMUM/hqdefault.jpg Overview of Longevity Sciences The Longevity Sciences Industry is multi-faceted, with new approaches being explored globally. Key segments include: Senolytics and Senescence: These focus on removing or rejuvenating senescent cells, which accumulate with age and contribute to various age-related diseases. Telomere Research: Telomeres, protective caps at the end of chromosomes, play a role in cellular aging. Research aims to maintain or lengthen telomeres. Metabolic Interventions: Caloric restriction, intermittent fasting, and mimetics (such as resveratrol) target metabolic pathways to promote longevity. Epigenetics: Understanding how gene expression changes with age and finding ways to modulate it for healthier aging. Stem Cell Therapies: Using stem cells to regenerate damaged tissues and organs. Biological Clocks: Investigating biological clocks (e.g., circadian rhythms) and their impact on aging. NAD+ Boosters: NAD+ is crucial for cellular energy production. Boosting NAD+ levels may enhance health span. AI and Longevity: Machine learning and AI help analyze large datasets and identify potential interventions. https://www.youtube-nocookie.com/embed/3qvlKdJgMUM 3958 2024-09-18T18:59:24.000Z 2026-10-22T19:43:47.895Z https://longevityharbor.com/de/watch/3qvlKdJgMUM Overview of Longevity Sciences | Davos In The Desert | Longevity Science Conference 2024 #stemcell https://i.ytimg.com/vi/3qvlKdJgMUM/hqdefault.jpg Overview of Longevity Sciences The Longevity Sciences Industry is multi-faceted, with new approaches being explored globally. Key segments include: Senolytics and Senescence: These focus on removing or rejuvenating senescent cells, which accumulate with age and contribute to various age-related diseases. Telomere Research: Telomeres, protective caps at the end of chromosomes, play a role in cellular aging. Research aims to maintain or lengthen telomeres. Metabolic Interventions: Caloric restriction, intermittent fasting, and mimetics (such as resveratrol) target metabolic pathways to promote longevity. Epigenetics: Understanding how gene expression changes with age and finding ways to modulate it for healthier aging. Stem Cell Therapies: Using stem cells to regenerate damaged tissues and organs. Biological Clocks: Investigating biological clocks (e.g., circadian rhythms) and their impact on aging. NAD+ Boosters: NAD+ is crucial for cellular energy production. Boosting NAD+ levels may enhance health span. AI and Longevity: Machine learning and AI help analyze large datasets and identify potential interventions. https://www.youtube-nocookie.com/embed/3qvlKdJgMUM 3958 2024-09-18T18:59:24.000Z 2026-10-22T19:43:47.895Z https://longevityharbor.com/en/watch/3r56QSWmADU Episode 2: Your Mighty Mitochondria - Feeding your cellular engines https://i.ytimg.com/vi/3r56QSWmADU/hqdefault.jpg Discover how your mitochondria—your body's tiny power plants—impact your energy, aging, and overall health. In this episode: mitophagy (cellular cleanup), urolithin A, and practical food strategies to support mitochondrial function. ⚠️ DISCLAIMER This content is educational only and not medical advice. I’m not a doctor—honestly, I barely passed chemistry! Always talk with your healthcare provider before trying supplements, diets, or new routines. Conflict of Interest Note: Some researchers discussed (Andreux et al.) have commercial interests in urolithin A products. I have no affiliations. 🏷️ TIMESTAMPS 0:00 Intro1:24 Why I’m doing this series5:16 Confession6:30 Mitochondria 1019:32 Quality over Quantity14:32 Paper 1: Palikaras21:13 Paper 2: Andreux30:00 Connecting the papers35:00 Kitchen Application: Walnut-Crusted Salmon35:40 Microbiome Resources52:00 Pomegranate Tea53:00 Limitations54:25 Wrap-Up & Next Week 📚 PAPERS DISCUSSED Paper 1: Palikaras et al. (2017). Mitophagy and Age-Related Pathologies.https://doi.org/10.1016/j.pharmthera.2017.04.005 Paper 2: Andreux et al. (2019). Urolithin A and Mitochondrial Health. https://doi.org/10.1038/s42255-019-0073-4Referenced: López-Otín et al. (2023). Hallmarks of Aging. https://doi.org/10.1016/j.cell.2022.11.001 🔬 KEY TERMS Mitochondria: Cellular energy producers Mitophagy: Cleanup of damaged mitochondria ATP: Energy currency Biogenesis: Making new mitochondria Free Radicals: “Sparks” that cause damage Ellagitannins: Compounds in pomegranates, walnuts, berries Urolithin A: Molecule from gut bacteria that activates mitophagy Homeostasis: Balance of removing/building mitochondria 🍽️ RECIPE Walnut-Crusted Salmon + Cranberry-Pomegranate RelishFull recipe: https://drive.google.com/file/d/17yk_ZbSpa_fIn1nUdL7DS3dCJFPQ9o8O/view?usp=sharingInspired by chef Reilly Meehan. 🧬 GUT MICROBIOME TESTING RESOURCES Tiny Health (Preferred for urolithin A producer status) Technology: Shotgun metagenomics (gold standard) Identifies specific bacteria: Enterocloster bolteae, Gordon https://www.youtube-nocookie.com/embed/3r56QSWmADU 3427 2025-11-26T19:02:26.000Z 2026-10-22T19:54:19.198Z https://longevityharbor.com/de/watch/3r56QSWmADU Episode 2: Your Mighty Mitochondria - Feeding your cellular engines https://i.ytimg.com/vi/3r56QSWmADU/hqdefault.jpg Discover how your mitochondria—your body's tiny power plants—impact your energy, aging, and overall health. In this episode: mitophagy (cellular cleanup), urolithin A, and practical food strategies to support mitochondrial function. ⚠️ DISCLAIMER This content is educational only and not medical advice. I’m not a doctor—honestly, I barely passed chemistry! Always talk with your healthcare provider before trying supplements, diets, or new routines. Conflict of Interest Note: Some researchers discussed (Andreux et al.) have commercial interests in urolithin A products. I have no affiliations. 🏷️ TIMESTAMPS 0:00 Intro1:24 Why I’m doing this series5:16 Confession6:30 Mitochondria 1019:32 Quality over Quantity14:32 Paper 1: Palikaras21:13 Paper 2: Andreux30:00 Connecting the papers35:00 Kitchen Application: Walnut-Crusted Salmon35:40 Microbiome Resources52:00 Pomegranate Tea53:00 Limitations54:25 Wrap-Up & Next Week 📚 PAPERS DISCUSSED Paper 1: Palikaras et al. (2017). Mitophagy and Age-Related Pathologies.https://doi.org/10.1016/j.pharmthera.2017.04.005 Paper 2: Andreux et al. (2019). Urolithin A and Mitochondrial Health. https://doi.org/10.1038/s42255-019-0073-4Referenced: López-Otín et al. (2023). Hallmarks of Aging. https://doi.org/10.1016/j.cell.2022.11.001 🔬 KEY TERMS Mitochondria: Cellular energy producers Mitophagy: Cleanup of damaged mitochondria ATP: Energy currency Biogenesis: Making new mitochondria Free Radicals: “Sparks” that cause damage Ellagitannins: Compounds in pomegranates, walnuts, berries Urolithin A: Molecule from gut bacteria that activates mitophagy Homeostasis: Balance of removing/building mitochondria 🍽️ RECIPE Walnut-Crusted Salmon + Cranberry-Pomegranate RelishFull recipe: https://drive.google.com/file/d/17yk_ZbSpa_fIn1nUdL7DS3dCJFPQ9o8O/view?usp=sharingInspired by chef Reilly Meehan. 🧬 GUT MICROBIOME TESTING RESOURCES Tiny Health (Preferred for urolithin A producer status) Technology: Shotgun metagenomics (gold standard) Identifies specific bacteria: Enterocloster bolteae, Gordon https://www.youtube-nocookie.com/embed/3r56QSWmADU 3427 2025-11-26T19:02:26.000Z 2026-10-22T19:54:19.198Z https://longevityharbor.com/en/watch/3r_jK8jeN9w Video description on NMN: NAD⁺ link, human studies and exaggerated claims https://i.ytimg.com/vi/3r_jK8jeN9w/hqdefault.jpg According to the description, this episode examines the research behind NMN, its relation to NAD⁺, proposed effects on ageing, energy and metabolism, what human studies show, and misconceptions and safety questions. The creator says it is research-focused and not intended to promote miracle claims. https://www.youtube-nocookie.com/embed/3r_jK8jeN9w 121 2026-05-14T02:00:39.000Z 2026-10-23T01:04:52.739Z https://longevityharbor.com/de/watch/3r_jK8jeN9w Videobeschreibung zu NMN: NAD⁺-Bezug, Humanstudien und übertriebene Aussagen https://i.ytimg.com/vi/3r_jK8jeN9w/hqdefault.jpg Laut Beschreibung untersucht diese Episode die Forschung zu NMN, den Bezug zu NAD⁺, vorgeschlagene Wirkungen auf Altern, Energie und Stoffwechsel, was Humanstudien zeigen sowie Missverständnisse und Sicherheitsfragen. Der Ersteller bezeichnet sie als forschungsorientiert und nicht als Werbung für Wunderversprechen. https://www.youtube-nocookie.com/embed/3r_jK8jeN9w 121 2026-05-14T02:00:39.000Z 2026-10-23T01:04:52.739Z https://longevityharbor.com/en/watch/3v0hZe4niW0 Organ-specific aging clocks reviewed in Nature Medicine https://i.ytimg.com/vi/3v0hZe4niW0/hqdefault.jpg A Nature Medicine review described in this video looks at aging clocks based on epigenetic, proteomic, cellular, imaging and artificial intelligence data, and their possible use in predicting disease, guiding prevention and assessing whether aging can be modified. https://www.youtube-nocookie.com/embed/3v0hZe4niW0 144 2026-07-10T09:06:43.000Z 2026-10-22T23:38:58.566Z https://longevityharbor.com/de/watch/3v0hZe4niW0 Organspezifische Alternsuhren in Nature Medicine besprochen https://i.ytimg.com/vi/3v0hZe4niW0/hqdefault.jpg Eine in diesem Video beschriebene Nature-Medicine-Übersicht betrachtet Alternsuhren auf Basis epigenetischer, proteomischer, zellulärer, bildgebender und KI-gestützter Daten und ihren möglichen Nutzen bei Krankheitsvorhersage, Prävention und der Frage, ob Altern veränderbar ist. https://www.youtube-nocookie.com/embed/3v0hZe4niW0 144 2026-07-10T09:06:43.000Z 2026-10-22T23:38:58.566Z https://longevityharbor.com/en/watch/3wngpV7jyAI Podcast: Dr. Barzilai on aging clocks, hype and longevity medicine https://i.ytimg.com/vi/3wngpV7jyAI/hqdefault.jpg In this podcast description, Dr. Kara Fitzgerald and longevity physician Dr. David Barzilai discuss biological age testing such as DunedinPACE, separating longevity science from hype, and where longevity medicine may be headed. https://www.youtube-nocookie.com/embed/3wngpV7jyAI 4227 2026-09-25T14:13:09.000Z 2026-10-22T21:49:12.634Z https://longevityharbor.com/de/watch/3wngpV7jyAI Podcast: Dr. Barzilai über Altersuhren, Hype und Langlebigkeitsmedizin https://i.ytimg.com/vi/3wngpV7jyAI/hqdefault.jpg In dieser Podcast-Beschreibung sprechen Dr. Kara Fitzgerald und der Langlebigkeitsmediziner Dr. David Barzilai über biologische Altersmessungen wie DunedinPACE, die Trennung von Wissenschaft und Hype und die mögliche Zukunft der Langlebigkeitsmedizin. https://www.youtube-nocookie.com/embed/3wngpV7jyAI 4227 2026-09-25T14:13:09.000Z 2026-10-22T21:49:12.634Z https://longevityharbor.com/en/watch/3yzX18FZU4A Using Aging Research to Improve Resilience in Older Adults https://i.ytimg.com/vi/3yzX18FZU4A/hqdefault.jpg Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Recorded on 09/25/2025. [Show ID: 40961] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Resilience and Healthy Aging Symposium (https://www.uctv.tv/resilience-healthy-aging) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by pro https://www.youtube-nocookie.com/embed/3yzX18FZU4A 2886 2025-10-16T02:00:03.000Z 2026-10-22T17:43:40.153Z https://longevityharbor.com/de/watch/3yzX18FZU4A Using Aging Research to Improve Resilience in Older Adults https://i.ytimg.com/vi/3yzX18FZU4A/hqdefault.jpg Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Recorded on 09/25/2025. [Show ID: 40961] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Resilience and Healthy Aging Symposium (https://www.uctv.tv/resilience-healthy-aging) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by pro https://www.youtube-nocookie.com/embed/3yzX18FZU4A 2886 2025-10-16T02:00:03.000Z 2026-10-22T17:43:40.153Z https://longevityharbor.com/en/watch/40HZEDgXHNQ Video description compares NMN and astaxanthin supplements https://i.ytimg.com/vi/40HZEDgXHNQ/hqdefault.jpg The description presents NMN as supporting cellular energy by boosting NAD+ levels and astaxanthin as an antioxidant that helps protect cells from oxidative stress, with skin, joint and recovery support. It gives no study data and is a promotional supplement video. https://www.youtube-nocookie.com/embed/40HZEDgXHNQ 135 2026-08-08T17:13:12.000Z 2026-10-22T23:08:22.901Z https://longevityharbor.com/de/watch/40HZEDgXHNQ Videobeschreibung vergleicht NMN- und Astaxanthin-Präparate https://i.ytimg.com/vi/40HZEDgXHNQ/hqdefault.jpg Die Beschreibung stellt NMN als Unterstützung der zellulären Energie durch erhöhte NAD+-Spiegel dar und Astaxanthin als Antioxidans, das Zellen vor oxidativem Stress schützen soll, mit Unterstützung für Haut, Gelenke und Erholung. Studiendaten fehlen; es handelt sich um ein werbliches Nahrungsergänzungsvideo. https://www.youtube-nocookie.com/embed/40HZEDgXHNQ 135 2026-08-08T17:13:12.000Z 2026-10-22T23:08:22.901Z https://longevityharbor.com/en/watch/43OJuHumMjs Dietary alternatives to long-term caloric restriction | Peter Attia & Steven Austad https://i.ytimg.com/vi/43OJuHumMjs/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/WNKRSiSGvGE Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode #171 of The Drive - Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules | Steve Austad, Ph.D. In this episode, Peter is joined by Steve Austad, Ph.D. a distinguished professor of biology at the University of Alabama and director of one of the Nathan Shock Centers of Excellence in aging biology. In this clip, we discuss: - Ways to transition away from the typical American diet - Time restricted feeding - Which type of dietary restriction gives us the best insight on health benefits - How fasting and suppressing mTOR can have multiple health benefits -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 60 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this inf https://www.youtube-nocookie.com/embed/43OJuHumMjs 626 2023-07-08T16:00:03.000Z 2026-10-22T17:43:38.453Z https://longevityharbor.com/de/watch/43OJuHumMjs Dietary alternatives to long-term caloric restriction | Peter Attia & Steven Austad https://i.ytimg.com/vi/43OJuHumMjs/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/WNKRSiSGvGE Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode #171 of The Drive - Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules | Steve Austad, Ph.D. In this episode, Peter is joined by Steve Austad, Ph.D. a distinguished professor of biology at the University of Alabama and director of one of the Nathan Shock Centers of Excellence in aging biology. In this clip, we discuss: - Ways to transition away from the typical American diet - Time restricted feeding - Which type of dietary restriction gives us the best insight on health benefits - How fasting and suppressing mTOR can have multiple health benefits -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 60 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this inf https://www.youtube-nocookie.com/embed/43OJuHumMjs 626 2023-07-08T16:00:03.000Z 2026-10-22T17:43:38.453Z https://longevityharbor.com/en/watch/478VNVqHK0Q Caloric Restriction: The Science Behind Longevity Through Diet https://i.ytimg.com/vi/478VNVqHK0Q/hqdefault.jpg Caloric Restriction and Longevity: Science or the Key to a Longer Life? Caloric restriction—reducing daily calorie intake without malnutrition—has been linked to increased lifespan and improved health across various species, from yeast and worms to mammals like rodents and primates. Studies suggest that eating fewer calories triggers beneficial metabolic changes, including reduced oxidative stress, enhanced cellular repair, and improved hormonal balance, all of which may slow aging and extend lifespan. #CaloricRestriction #Longevity #HealthyAging #Metabolism #AntiAgingScience #CellularRepair One key mechanism behind caloric restriction is lower oxidative damage. When fewer calories are consumed, cells generate energy more efficiently, producing fewer reactive oxygen species (ROS), which can damage proteins, DNA, and cell membranes. Additionally, caloric restriction activates longevity-associated pathways: 🔹 Sirtuins (SIRT) – Proteins that regulate DNA repair, stress resistance, and metabolism. 🔹 AMPK (AMP-activated protein kinase) – Enhances energy efficiency and cellular repair. 🔹 mTOR inhibition – Slows cellular aging and promotes autophagy, the process of removing damaged cell components. In animal studies, mice on a calorie-restricted diet lived up to 50% longer than those on a normal diet. Similar effects have been observed in fruit flies and worms, with increased lifespan and stress resistance. In primate studies, caloric restriction improved metabolic health and reduced age-related diseases, though its full impact on lifespan is still under investigation. Key Topics Covered in This Video: 🥗 What Is Caloric Restriction? The science behind longevity through diet. 🧬 Cellular Benefits: How fewer calories enhance repair and reduce damage. 🔬 Sirtuins, AMPK & mTOR: The metabolic pathways involved in aging. 📉 Disease Prevention: Lower risks of diabetes, heart disease, and cancer. 🚀 Future Research: Can science replicate these benefits without extreme dieting? Context Timestamps: 00:00 - Introduction: https://www.youtube-nocookie.com/embed/478VNVqHK0Q 634 2025-03-13T05:44:18.000Z 2026-10-22T19:32:32.030Z https://longevityharbor.com/de/watch/478VNVqHK0Q Caloric Restriction: The Science Behind Longevity Through Diet https://i.ytimg.com/vi/478VNVqHK0Q/hqdefault.jpg Caloric Restriction and Longevity: Science or the Key to a Longer Life? Caloric restriction—reducing daily calorie intake without malnutrition—has been linked to increased lifespan and improved health across various species, from yeast and worms to mammals like rodents and primates. Studies suggest that eating fewer calories triggers beneficial metabolic changes, including reduced oxidative stress, enhanced cellular repair, and improved hormonal balance, all of which may slow aging and extend lifespan. #CaloricRestriction #Longevity #HealthyAging #Metabolism #AntiAgingScience #CellularRepair One key mechanism behind caloric restriction is lower oxidative damage. When fewer calories are consumed, cells generate energy more efficiently, producing fewer reactive oxygen species (ROS), which can damage proteins, DNA, and cell membranes. Additionally, caloric restriction activates longevity-associated pathways: 🔹 Sirtuins (SIRT) – Proteins that regulate DNA repair, stress resistance, and metabolism. 🔹 AMPK (AMP-activated protein kinase) – Enhances energy efficiency and cellular repair. 🔹 mTOR inhibition – Slows cellular aging and promotes autophagy, the process of removing damaged cell components. In animal studies, mice on a calorie-restricted diet lived up to 50% longer than those on a normal diet. Similar effects have been observed in fruit flies and worms, with increased lifespan and stress resistance. In primate studies, caloric restriction improved metabolic health and reduced age-related diseases, though its full impact on lifespan is still under investigation. Key Topics Covered in This Video: 🥗 What Is Caloric Restriction? The science behind longevity through diet. 🧬 Cellular Benefits: How fewer calories enhance repair and reduce damage. 🔬 Sirtuins, AMPK & mTOR: The metabolic pathways involved in aging. 📉 Disease Prevention: Lower risks of diabetes, heart disease, and cancer. 🚀 Future Research: Can science replicate these benefits without extreme dieting? Context Timestamps: 00:00 - Introduction: https://www.youtube-nocookie.com/embed/478VNVqHK0Q 634 2025-03-13T05:44:18.000Z 2026-10-22T19:32:32.030Z https://longevityharbor.com/en/watch/47D9HvWgC14 Can Fasting Help Me Live Longer? https://i.ytimg.com/vi/47D9HvWgC14/hqdefault.jpg 🎉 Welcome to The Longevity Lab! Your go-to community for credible, science-backed insights on healthspan and longevity. Want to stay informed, inspired, and connected as you build a healthier, longer life? Join here: https://chat.whatsapp.com/CYf7Ld8PaPkLaqeF0RrNUO 💡 For a limited time, it’s completely free! https://www.youtube-nocookie.com/embed/47D9HvWgC14 112 2025-05-29T09:18:47.000Z 2026-10-22T19:32:30.849Z https://longevityharbor.com/de/watch/47D9HvWgC14 Can Fasting Help Me Live Longer? https://i.ytimg.com/vi/47D9HvWgC14/hqdefault.jpg 🎉 Welcome to The Longevity Lab! Your go-to community for credible, science-backed insights on healthspan and longevity. Want to stay informed, inspired, and connected as you build a healthier, longer life? Join here: https://chat.whatsapp.com/CYf7Ld8PaPkLaqeF0RrNUO 💡 For a limited time, it’s completely free! https://www.youtube-nocookie.com/embed/47D9HvWgC14 112 2025-05-29T09:18:47.000Z 2026-10-22T19:32:30.849Z https://longevityharbor.com/en/watch/49ny_6bPtzo The Social Hallmarks Of Aging https://i.ytimg.com/vi/49ny_6bPtzo/hqdefault.jpg Earlier episodes have introduced the hallmarks of aging, a framework used to guide aging research and interpret the findings. In this series of three episodes, we’re going to explore the recently proposed social hallmarks of aging. The idea is that a set of social factors act as underlying, interrelated causes of age-related outcomes, similar to the way that the biological hallmarks underlie different diseases and disorders of aging. In the first episode, we discuss a paper that identified five social factors that have a strong effect on aging even when biological factors are taken into account. Addressing these could be a powerful tool in increasing the average lifespan. SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Crimmins EM. Social hallmarks of aging: Suggestions for geroscience research. Ageing Research Reviews (2020), doi: 10.1016/j.arr.2020.101136 López-Otín C, Blasco MA, Partridge L, Serrano M, and Kroemer G. The hallmarks of aging. Cell (2013), doi: 10.1016/j.cell.2013.05.039. FOOTAGE, IMAGES, AND MUSIC CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Stock pictures from Shutterstock Stock footage from Music: "Monkey races" by Eric Matyas Thumbnail font: Cocogoose Pro Family by Zetafonts -http://www.zetafonts.com/collection/308 ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #aging #longevity #socialissues #socialhallmarks #halmarksofaging https://www.youtube-nocookie.com/embed/49ny_6bPtzo 276 2021-07-28T16:00:02.000Z 2026-10-22T17:43:40.094Z https://longevityharbor.com/de/watch/49ny_6bPtzo The Social Hallmarks Of Aging https://i.ytimg.com/vi/49ny_6bPtzo/hqdefault.jpg Earlier episodes have introduced the hallmarks of aging, a framework used to guide aging research and interpret the findings. In this series of three episodes, we’re going to explore the recently proposed social hallmarks of aging. The idea is that a set of social factors act as underlying, interrelated causes of age-related outcomes, similar to the way that the biological hallmarks underlie different diseases and disorders of aging. In the first episode, we discuss a paper that identified five social factors that have a strong effect on aging even when biological factors are taken into account. Addressing these could be a powerful tool in increasing the average lifespan. SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Crimmins EM. Social hallmarks of aging: Suggestions for geroscience research. Ageing Research Reviews (2020), doi: 10.1016/j.arr.2020.101136 López-Otín C, Blasco MA, Partridge L, Serrano M, and Kroemer G. The hallmarks of aging. Cell (2013), doi: 10.1016/j.cell.2013.05.039. FOOTAGE, IMAGES, AND MUSIC CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Stock pictures from Shutterstock Stock footage from Music: "Monkey races" by Eric Matyas Thumbnail font: Cocogoose Pro Family by Zetafonts -http://www.zetafonts.com/collection/308 ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #aging #longevity #socialissues #socialhallmarks #halmarksofaging https://www.youtube-nocookie.com/embed/49ny_6bPtzo 276 2021-07-28T16:00:02.000Z 2026-10-22T17:43:40.094Z https://longevityharbor.com/en/watch/4AsrTjLqJxE How effective is NAD and its precursors for longevity? https://i.ytimg.com/vi/4AsrTjLqJxE/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/Io5xV9rtbm4?si=YbHDA2iR02950c9u Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 300 ‒ Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, & more. In this clip, they discuss: - Peter's current thoughts on NAD - What we still need to study about NAD to know if it's effective - Promising data supporting the efficacy of NAD - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition https://www.youtube-nocookie.com/embed/4AsrTjLqJxE 594 2024-05-17T16:00:03.000Z 2026-10-22T18:43:09.822Z https://longevityharbor.com/de/watch/4AsrTjLqJxE How effective is NAD and its precursors for longevity? https://i.ytimg.com/vi/4AsrTjLqJxE/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/Io5xV9rtbm4?si=YbHDA2iR02950c9u Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 300 ‒ Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, & more. In this clip, they discuss: - Peter's current thoughts on NAD - What we still need to study about NAD to know if it's effective - Promising data supporting the efficacy of NAD - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition https://www.youtube-nocookie.com/embed/4AsrTjLqJxE 594 2024-05-17T16:00:03.000Z 2026-10-22T18:43:09.822Z https://longevityharbor.com/en/watch/4BpBtwRdhik Video description: Sinclair's aging theory, zombie cells and fasting claims https://i.ytimg.com/vi/4BpBtwRdhik/hqdefault.jpg The description presents David Sinclair's Information Theory of Aging, calls senescent cells 'zombie cells' linked to joint pain and brain fog, and says intermittent fasting turns on autophagy and cold, heat and exercise wake sirtuin genes. https://www.youtube-nocookie.com/embed/4BpBtwRdhik 592 2026-05-26T18:00:06.000Z 2026-10-23T00:25:43.177Z https://longevityharbor.com/de/watch/4BpBtwRdhik Videobeschreibung: Sinclairs Alterungstheorie, Zombiezellen und Fasten-Aussagen https://i.ytimg.com/vi/4BpBtwRdhik/hqdefault.jpg Die Beschreibung stellt David Sinclairs Informationstheorie des Alterns vor, nennt seneszente Zellen „Zombiezellen“, die mit Gelenkschmerzen und Brain Fog verbunden werden, und sagt, Intervallfasten aktiviere Autophagie und Kälte, Hitze und Bewegung weckten Sirtuin-Gene. https://www.youtube-nocookie.com/embed/4BpBtwRdhik 592 2026-05-26T18:00:06.000Z 2026-10-23T00:25:43.177Z https://longevityharbor.com/en/watch/4HCsw5cexcA The Mystery of Aging—And Why Science Is Finally Catching Up https://i.ytimg.com/vi/4HCsw5cexcA/hqdefault.jpg ReProgram Episode 2 IWhat is aging, and can we actually reverse it? We examine the current science to separate biological reality from speculation. The definition of aging remains fluid, yet it is a universal process that impacts every biological system. We explore the distinction between chronological time and biological age, analyzing how current metrics help us quantify physiological decline rather than just counting birthdays. This discussion covers the foundational hallmarks of aging and the emerging field of geroscience. We look at how epigenetics influences these processes and evaluate whether true age reversal is a scientific possibility at the cellular level or currently limited to theoretical models. If you value longevity science without the hype, subscribe to The ReProgram. Keywords aging, science, medicine, longevity, epigenetics, biological clocks, senescence, gene therapy, regenerative medicine, immortality, geroscience Takeaways Aging is a complex and mysterious process and is defined variably by different scientists. Modern science is exploring senolytic drugs and gene therapies. The hallmarks of aging provide a framework for understanding the process. Biological aging clocks are a tool for measuring age. Epigenetics play a key role in how we age. Aging is a universal process affecting everyone. Research is ongoing to find ways to slow or reverse aging. Age reversal is possible at the cellular level, but is not yet a reality for humans. Office Artifact On the desk: Ostrich egg from South Africa Chapters 00:00 The Mystery of Aging 03:01 Understanding Aging: Damage Accumulation and Resilience 06:10 The Hallmarks of Aging 08:54 Epigenetics: The Key to Biological Age 12:11 Age Reversal: Resetting the Slinky Notes: Seminal Hallmarks of Aging Paper: https://pubmed.ncbi.nlm.nih.gov/23746838/ https://www.youtube-nocookie.com/embed/4HCsw5cexcA 832 2025-11-17T17:00:07.000Z 2026-10-22T18:32:11.626Z https://longevityharbor.com/de/watch/4HCsw5cexcA The Mystery of Aging—And Why Science Is Finally Catching Up https://i.ytimg.com/vi/4HCsw5cexcA/hqdefault.jpg ReProgram Episode 2 IWhat is aging, and can we actually reverse it? We examine the current science to separate biological reality from speculation. The definition of aging remains fluid, yet it is a universal process that impacts every biological system. We explore the distinction between chronological time and biological age, analyzing how current metrics help us quantify physiological decline rather than just counting birthdays. This discussion covers the foundational hallmarks of aging and the emerging field of geroscience. We look at how epigenetics influences these processes and evaluate whether true age reversal is a scientific possibility at the cellular level or currently limited to theoretical models. If you value longevity science without the hype, subscribe to The ReProgram. Keywords aging, science, medicine, longevity, epigenetics, biological clocks, senescence, gene therapy, regenerative medicine, immortality, geroscience Takeaways Aging is a complex and mysterious process and is defined variably by different scientists. Modern science is exploring senolytic drugs and gene therapies. The hallmarks of aging provide a framework for understanding the process. Biological aging clocks are a tool for measuring age. Epigenetics play a key role in how we age. Aging is a universal process affecting everyone. Research is ongoing to find ways to slow or reverse aging. Age reversal is possible at the cellular level, but is not yet a reality for humans. Office Artifact On the desk: Ostrich egg from South Africa Chapters 00:00 The Mystery of Aging 03:01 Understanding Aging: Damage Accumulation and Resilience 06:10 The Hallmarks of Aging 08:54 Epigenetics: The Key to Biological Age 12:11 Age Reversal: Resetting the Slinky Notes: Seminal Hallmarks of Aging Paper: https://pubmed.ncbi.nlm.nih.gov/23746838/ https://www.youtube-nocookie.com/embed/4HCsw5cexcA 832 2025-11-17T17:00:07.000Z 2026-10-22T18:32:11.626Z https://longevityharbor.com/en/watch/4LcQdJ_IQMM Rapamycin explained: mTOR, animal lifespan data and open human questions https://i.ytimg.com/vi/4LcQdJ_IQMM/hqdefault.jpg The description says rapamycin is among the most studied longevity compounds and works through mTOR inhibition; laboratory data from yeast to primates reportedly show lifespan extension, but human use, side effects and dosing remain open questions. https://www.youtube-nocookie.com/embed/4LcQdJ_IQMM 498 2026-02-15T01:48:24.000Z 2026-10-23T02:33:42.338Z https://longevityharbor.com/de/watch/4LcQdJ_IQMM Rapamycin erklärt: mTOR, Tier-Lebensspannen-Daten und offene Fragen beim Menschen https://i.ytimg.com/vi/4LcQdJ_IQMM/hqdefault.jpg Laut Beschreibung gehört Rapamycin zu den am besten untersuchten Langlebigkeits-Verbindungen und wirkt über mTOR-Hemmung; Labordaten von Hefe bis zu Primaten zeigen demnach eine verlängerte Lebensspanne, doch Nutzung beim Menschen, Nebenwirkungen und Dosierung bleiben offene Fragen. https://www.youtube-nocookie.com/embed/4LcQdJ_IQMM 498 2026-02-15T01:48:24.000Z 2026-10-23T02:33:42.338Z https://longevityharbor.com/en/watch/4MIMwpeGwmo Inflammaging proposed in 2000 as a driver of age-related disease https://i.ytimg.com/vi/4MIMwpeGwmo/hqdefault.jpg The description says a 2000 paper by Claudio Franceschi and colleagues proposed inflammaging: chronic, low-grade, sterile inflammation as a hallmark of aging and a proposed active driver of age-related diseases. https://www.youtube-nocookie.com/embed/4MIMwpeGwmo 652 2026-08-27T09:27:26.000Z 2026-10-22T22:41:32.267Z https://longevityharbor.com/de/watch/4MIMwpeGwmo Inflammaging 2000 als Treiber altersbezogener Krankheiten vorgeschlagen https://i.ytimg.com/vi/4MIMwpeGwmo/hqdefault.jpg Laut Beschreibung schlug eine Arbeit von Claudio Franceschi und Kollegen 2000 „Inflammaging“ vor: chronische, niedriggradige, sterile Entzündung als Kennzeichen des Alterns und als vorgeschlagener aktiver Treiber altersbezogener Krankheiten. https://www.youtube-nocookie.com/embed/4MIMwpeGwmo 652 2026-08-27T09:27:26.000Z 2026-10-22T22:41:32.267Z https://longevityharbor.com/en/watch/4O5li45zxMc Book description: exercise, nutrition and stress for healthy ageing https://i.ytimg.com/vi/4O5li45zxMc/hqdefault.jpg The description presents Thomas Kälicke's book LNGVTY as a guide to exercise, nutrition, sleep and stress management for healthy ageing, and claims only 20–30% of lifespan is genetically predetermined. https://www.youtube-nocookie.com/embed/4O5li45zxMc 185 2026-09-27T18:27:39.000Z 2026-10-22T21:43:42.255Z https://longevityharbor.com/de/watch/4O5li45zxMc Buchbeschreibung: Bewegung, Ernährung und Stress für gesundes Altern https://i.ytimg.com/vi/4O5li45zxMc/hqdefault.jpg Die Beschreibung stellt Thomas Kälickes Buch LNGVTY als Leitfaden zu Bewegung, Ernährung, Schlaf und Stressbewältigung für gesundes Altern vor und behauptet, nur 20–30% der Lebensspanne seien genetisch vorgegeben. https://www.youtube-nocookie.com/embed/4O5li45zxMc 185 2026-09-27T18:27:39.000Z 2026-10-22T21:43:42.255Z https://longevityharbor.com/en/watch/4P27OY9fekg Book description: HIT strength training and muscle loss with age https://i.ytimg.com/vi/4P27OY9fekg/hqdefault.jpg The description presents Prof. Dr. Dr. Jürgen Gießing's book Reverse Aging, which claims muscle loss begins around age 30 and proposes high-intensity training (HIT) twice weekly, plus protein and creatine strategies, to counter sarcopenia. https://www.youtube-nocookie.com/embed/4P27OY9fekg 2303 2026-08-12T11:27:36.000Z 2026-10-22T23:06:05.289Z https://longevityharbor.com/de/watch/4P27OY9fekg Buchbeschreibung: HIT-Krafttraining und Muskelabbau im Alter https://i.ytimg.com/vi/4P27OY9fekg/hqdefault.jpg Die Beschreibung stellt Prof. Dr. Dr. Jürgen Gießings Buch Reverse Aging vor: Muskelabbau beginne etwa mit 30, und ein Hochintensitätstraining (HIT) zweimal pro Woche sowie Strategien zu Protein und Kreatin sollen Sarkopenie entgegenwirken. https://www.youtube-nocookie.com/embed/4P27OY9fekg 2303 2026-08-12T11:27:36.000Z 2026-10-22T23:06:05.289Z https://longevityharbor.com/en/watch/4PdmqNMu8YI How to Slow Down Biological Aging (The Longevity Blueprint) | Matt Kaeberlein | AFP 40 https://i.ytimg.com/vi/4PdmqNMu8YI/hqdefault.jpg What if getting older didn’t have to mean getting sicker? Discover the science-backed blueprint to slow down biological aging, optimize your healthspan, and prevent disease. Join Jeroen Schreel and Matt Kaeberlein, a professor of Oral Health Sciences at the University of Washington and CEO of Optispan, as they delve into the science of biological aging. Discover how your daily habits, nutrient strategies, emerging therapeutics, and powerful new research could help you live a longer, healthier life. 00:00 Intro 00:34 Ads 02:15 Why Body Size Affects Longevity 03:52 IGF-1 Growth Factors and the Rate of Aging 05:26 What is Biological Aging? 06:28 Homeostasis, Entropy, and the Physics of Aging 08:00 Why Humans Live Beyond Reproductive Years 09:37 Programmed Aging vs. Evolutionary Byproducts 10:34 Healthspan vs. Lifespan: What Really Matters? 12:00 Compression of Morbidity: Maximizing Quality of Life 13:06 Can You Increase Lifespan Without Healthspan? 14:35 Barriers to Human Lifespan 15:41 Why Humans Age at Different Rates 17:11 Genetics vs. Environment: Impact After Age 50 18:47 Epigenetics: How Lifestyle Controls Gene Expression 19:53 The 12 Hallmarks of Aging 20:26 The 4 Pillars of Health: Eat, Move, Sleep, Connect 21:50 Matt's Nutrition Strategy: Whole Foods for Longevity 22:21 The Biological Danger of Added Sugars 23:09 Intermittent Fasting vs. Total Caloric Intake 24:33 Alcohol and Aging: How Much is Too Much? 24:58 High Protein Diets and Muscle Mass Maintenance 25:59 Resistance Training vs. Cardiovascular Exercise 27:18 Maintaining Bone Density and Lean Mass 27:42 Muscle as Metabolic Defense Against Diabetes 28:40 Sleep Hygiene and the Impact of Alcohol 29:39 Human Connection: Loneliness and Longevity 31:12 Why Added Sugars Accelerate the Aging Process 32:07 Insulin Sensitivity and the Obesity Epidemic 33:29 Continuous Glucose Monitors (CGM) for Health 35:22 Natural Sugars vs. Added Sugars 35:58 Hormesis: Stressing Your Body for Longevity 36:27 Does Fasting Actually Extend Lifespan? 43:15 Autophagy Myths and https://www.youtube-nocookie.com/embed/4PdmqNMu8YI 4784 2025-04-29T22:00:06.000Z 2026-10-22T17:43:39.291Z https://longevityharbor.com/de/watch/4PdmqNMu8YI How to Slow Down Biological Aging (The Longevity Blueprint) | Matt Kaeberlein | AFP 40 https://i.ytimg.com/vi/4PdmqNMu8YI/hqdefault.jpg What if getting older didn’t have to mean getting sicker? Discover the science-backed blueprint to slow down biological aging, optimize your healthspan, and prevent disease. Join Jeroen Schreel and Matt Kaeberlein, a professor of Oral Health Sciences at the University of Washington and CEO of Optispan, as they delve into the science of biological aging. Discover how your daily habits, nutrient strategies, emerging therapeutics, and powerful new research could help you live a longer, healthier life. 00:00 Intro 00:34 Ads 02:15 Why Body Size Affects Longevity 03:52 IGF-1 Growth Factors and the Rate of Aging 05:26 What is Biological Aging? 06:28 Homeostasis, Entropy, and the Physics of Aging 08:00 Why Humans Live Beyond Reproductive Years 09:37 Programmed Aging vs. Evolutionary Byproducts 10:34 Healthspan vs. Lifespan: What Really Matters? 12:00 Compression of Morbidity: Maximizing Quality of Life 13:06 Can You Increase Lifespan Without Healthspan? 14:35 Barriers to Human Lifespan 15:41 Why Humans Age at Different Rates 17:11 Genetics vs. Environment: Impact After Age 50 18:47 Epigenetics: How Lifestyle Controls Gene Expression 19:53 The 12 Hallmarks of Aging 20:26 The 4 Pillars of Health: Eat, Move, Sleep, Connect 21:50 Matt's Nutrition Strategy: Whole Foods for Longevity 22:21 The Biological Danger of Added Sugars 23:09 Intermittent Fasting vs. Total Caloric Intake 24:33 Alcohol and Aging: How Much is Too Much? 24:58 High Protein Diets and Muscle Mass Maintenance 25:59 Resistance Training vs. Cardiovascular Exercise 27:18 Maintaining Bone Density and Lean Mass 27:42 Muscle as Metabolic Defense Against Diabetes 28:40 Sleep Hygiene and the Impact of Alcohol 29:39 Human Connection: Loneliness and Longevity 31:12 Why Added Sugars Accelerate the Aging Process 32:07 Insulin Sensitivity and the Obesity Epidemic 33:29 Continuous Glucose Monitors (CGM) for Health 35:22 Natural Sugars vs. Added Sugars 35:58 Hormesis: Stressing Your Body for Longevity 36:27 Does Fasting Actually Extend Lifespan? 43:15 Autophagy Myths and https://www.youtube-nocookie.com/embed/4PdmqNMu8YI 4784 2025-04-29T22:00:06.000Z 2026-10-22T17:43:39.291Z https://longevityharbor.com/en/watch/4Ru-dFJNYRc The REAL Reasons to Use Nicotinamide Adenine Dinucleotide (NAD+) https://i.ytimg.com/vi/4Ru-dFJNYRc/hqdefault.jpg CMEs with Dr. A: https://www.consultdranderson.com Dr. A discusses the importance of NAD+, a crucial component for overall health and wellness. This video explains, "what is an NAD supplement" and how it functions within the body, as well as ways to maintain or boost NAD levels. He also emphasizes the significance of nicotinamide adenine dinucleotide for longevity. ____________________________ CHAPTERS 00:00 Intro: Why Everyone’s Talking About NAD 00:24 What Is NAD+ & What Does It Do? 01:46 How Your Body Makes NAD+ 02:15 NAD’s Role in Energy & Mitochondria 03:17 NAD in Brain, Detox & Histamine Pathways 04:13 Why It’s Popular for Energy & Recovery 04:34 Supplements to Raise NAD Naturally 05:17 How I Support NAD in Practice 06:05 Niacin vs. Niacinamide: Which Is Better? 06:47 NMN vs. NR: What’s the Difference? 08:37 IV NAD vs. Oral NAD Supplements 09:28 NAD Side Effects & How to Start Safely 10:42 When to Use Stronger NAD Support ___________________________ This video is NOT sponsored. Helpful Links CE COURSES FOR PROFESSIONALS: https://bit.ly/dra-continuingeducation Continuing Education for Professionals: consultdranderson.com Methylene Blue CE Webinar: https://www.consultdranderson.com/product/107-methylene-blue/ Probiotics Research Paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC10470842/ Connect with Dr. Anderson ~ Dr A YouTube Channel: https://www.youtube.com/channel/UC1FLIaKDzkU5Z0knDYYKyPQ Dr A Instagram: https://www.instagram.com/draonline/ Dr A Links: https://linktr.ee/DrAonline Dr A Website: https://dranow.com/ Consult with Dr. A- https://www.consultdranderson.com/product/vitamin-c-webinar-bundle/ ____________________________ INTEGRATIVE MEDICINE REFERRAL LINKS (Use these to find providers.) [For your reference only – no referral or implication of professional superiority is claimed or intended.] NAEM (Environmental Medicine) Providers: https://envmedicine.com/find-a-provider/ US Naturopathic Physicians: https://naturopathic.org/search/default.asp?m=radius Canadian Naturopathic https://www.youtube-nocookie.com/embed/4Ru-dFJNYRc 737 2025-08-06T13:00:15.000Z 2026-10-22T18:43:09.993Z https://longevityharbor.com/de/watch/4Ru-dFJNYRc The REAL Reasons to Use Nicotinamide Adenine Dinucleotide (NAD+) https://i.ytimg.com/vi/4Ru-dFJNYRc/hqdefault.jpg CMEs with Dr. A: https://www.consultdranderson.com Dr. A discusses the importance of NAD+, a crucial component for overall health and wellness. This video explains, "what is an NAD supplement" and how it functions within the body, as well as ways to maintain or boost NAD levels. He also emphasizes the significance of nicotinamide adenine dinucleotide for longevity. ____________________________ CHAPTERS 00:00 Intro: Why Everyone’s Talking About NAD 00:24 What Is NAD+ & What Does It Do? 01:46 How Your Body Makes NAD+ 02:15 NAD’s Role in Energy & Mitochondria 03:17 NAD in Brain, Detox & Histamine Pathways 04:13 Why It’s Popular for Energy & Recovery 04:34 Supplements to Raise NAD Naturally 05:17 How I Support NAD in Practice 06:05 Niacin vs. Niacinamide: Which Is Better? 06:47 NMN vs. NR: What’s the Difference? 08:37 IV NAD vs. Oral NAD Supplements 09:28 NAD Side Effects & How to Start Safely 10:42 When to Use Stronger NAD Support ___________________________ This video is NOT sponsored. Helpful Links CE COURSES FOR PROFESSIONALS: https://bit.ly/dra-continuingeducation Continuing Education for Professionals: consultdranderson.com Methylene Blue CE Webinar: https://www.consultdranderson.com/product/107-methylene-blue/ Probiotics Research Paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC10470842/ Connect with Dr. Anderson ~ Dr A YouTube Channel: https://www.youtube.com/channel/UC1FLIaKDzkU5Z0knDYYKyPQ Dr A Instagram: https://www.instagram.com/draonline/ Dr A Links: https://linktr.ee/DrAonline Dr A Website: https://dranow.com/ Consult with Dr. A- https://www.consultdranderson.com/product/vitamin-c-webinar-bundle/ ____________________________ INTEGRATIVE MEDICINE REFERRAL LINKS (Use these to find providers.) [For your reference only – no referral or implication of professional superiority is claimed or intended.] NAEM (Environmental Medicine) Providers: https://envmedicine.com/find-a-provider/ US Naturopathic Physicians: https://naturopathic.org/search/default.asp?m=radius Canadian Naturopathic https://www.youtube-nocookie.com/embed/4Ru-dFJNYRc 737 2025-08-06T13:00:15.000Z 2026-10-22T18:43:09.993Z https://longevityharbor.com/en/watch/4Sw2DiMSnNY How does FASTING affect your HEALTH?Ep.31 https://i.ytimg.com/vi/4Sw2DiMSnNY/hqdefault.jpg Join us in this episode as we delve into the intriguing topic of fasting and the fasting mimicking diet, and their profound impact on healthy lifespan. Our esteemed guest, Dr. Valter Longo, PhD in biochemistry and the Edna M. Jones Professor of Gerontology and Biological Sciences at the University of Southern California – Leonard Davis School of Gerontology, Los Angeles, shares invaluable insights from his extensive research at one of the foremost centers for aging and age-related disease studies. Dr. Longo, also serving as the Director of the Longevity and Cancer Program at the IFOM Institute of Molecular Oncology in Milan, Italy, brings a wealth of knowledge to the table. Through this engaging discussion, we explore the mechanisms behind fasting's effects on longevity, the science of the fasting mimicking diet, and its potential implications for human health and disease prevention. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez This conversation was based on the following article: Reference: Longo VD, Panda S. Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan. Cell Metab. 2016 Jun 14;23(6):1048-1059. doi: 10.1016/j.cmet.2016.06.001. PMID: 27304506; PMCID: PMC5388543. Chapters: 00:00 Coming up 02:13 Introduction 03:54 Motivation to start researching the topic 05:08 The importance of the circadian cycle for nutrition 08:30 Types of fasting 15:46 What is the fasting mimicking diet 16:55 Molecular changes during fasting 21:36 How diet can reduce inflammation 26:22 Effects on sleep and improvement in adherence 29:03 The balance between the fed and fast states 32:04 Browning of fat 36:00 The main goal for people who want to be healthy Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the info https://www.youtube-nocookie.com/embed/4Sw2DiMSnNY 2399 2024-05-01T18:21:47.000Z 2026-10-22T19:54:17.993Z https://longevityharbor.com/de/watch/4Sw2DiMSnNY How does FASTING affect your HEALTH?Ep.31 https://i.ytimg.com/vi/4Sw2DiMSnNY/hqdefault.jpg Join us in this episode as we delve into the intriguing topic of fasting and the fasting mimicking diet, and their profound impact on healthy lifespan. Our esteemed guest, Dr. Valter Longo, PhD in biochemistry and the Edna M. Jones Professor of Gerontology and Biological Sciences at the University of Southern California – Leonard Davis School of Gerontology, Los Angeles, shares invaluable insights from his extensive research at one of the foremost centers for aging and age-related disease studies. Dr. Longo, also serving as the Director of the Longevity and Cancer Program at the IFOM Institute of Molecular Oncology in Milan, Italy, brings a wealth of knowledge to the table. Through this engaging discussion, we explore the mechanisms behind fasting's effects on longevity, the science of the fasting mimicking diet, and its potential implications for human health and disease prevention. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez This conversation was based on the following article: Reference: Longo VD, Panda S. Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan. Cell Metab. 2016 Jun 14;23(6):1048-1059. doi: 10.1016/j.cmet.2016.06.001. PMID: 27304506; PMCID: PMC5388543. Chapters: 00:00 Coming up 02:13 Introduction 03:54 Motivation to start researching the topic 05:08 The importance of the circadian cycle for nutrition 08:30 Types of fasting 15:46 What is the fasting mimicking diet 16:55 Molecular changes during fasting 21:36 How diet can reduce inflammation 26:22 Effects on sleep and improvement in adherence 29:03 The balance between the fed and fast states 32:04 Browning of fat 36:00 The main goal for people who want to be healthy Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the info https://www.youtube-nocookie.com/embed/4Sw2DiMSnNY 2399 2024-05-01T18:21:47.000Z 2026-10-22T19:54:17.993Z https://longevityharbor.com/en/watch/4TSkiMzLv-Q Video description: eight everyday strategies for muscle strength in older adults https://i.ytimg.com/vi/4TSkiMzLv-Q/hqdefault.jpg A video description lists eight practical strategies said to help older adults maintain muscle strength, balance and everyday function, and advises professional advice before starting exercise with certain health conditions. https://www.youtube-nocookie.com/embed/4TSkiMzLv-Q 1365 2026-10-21T17:47:02.000Z 2026-10-22T19:47:42.544Z https://longevityharbor.com/de/watch/4TSkiMzLv-Q Videobeschreibung: acht Alltagsstrategien für Muskelkraft bei älteren Erwachsenen https://i.ytimg.com/vi/4TSkiMzLv-Q/hqdefault.jpg Eine Videobeschreibung nennt acht praktische Strategien, die älteren Erwachsenen helfen sollen, Muskelkraft, Gleichgewicht und Alltagsfunktion zu erhalten, und rät bei bestimmten Gesundheitsproblemen vor dem Trainingsbeginn zu professionellem Rat. https://www.youtube-nocookie.com/embed/4TSkiMzLv-Q 1365 2026-10-21T17:47:02.000Z 2026-10-22T19:47:42.544Z https://longevityharbor.com/en/watch/4XSOpox2pzc Video description: centenarians, resilience and 17 proposed categories https://i.ytimg.com/vi/4XSOpox2pzc/hqdefault.jpg The description says Dr. Rutherford discusses what people living to 100 share, why it is mostly not genetics, and previews 17 categories of physiological resilience; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/4XSOpox2pzc 1586 2026-09-01T21:35:49.000Z 2026-10-22T22:35:24.601Z https://longevityharbor.com/de/watch/4XSOpox2pzc Videobeschreibung: Hundertjährige, Resilienz und 17 vorgeschlagene Kategorien https://i.ytimg.com/vi/4XSOpox2pzc/hqdefault.jpg Laut Beschreibung erörtert Dr. Rutherford, was Menschen gemeinsam haben, die 100 werden, warum es überwiegend nicht die Genetik ist, und gibt einen Ausblick auf 17 Kategorien physiologischer Resilienz; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/4XSOpox2pzc 1586 2026-09-01T21:35:49.000Z 2026-10-22T22:35:24.601Z https://longevityharbor.com/en/watch/4cCEWiVywMQ UAB study examining impact of calorie reduction, intermittent fasting on aging process https://i.ytimg.com/vi/4cCEWiVywMQ/hqdefault.jpg UAB study examining impact of calorie reduction, intermittent fasting on aging process Subscribe to WVTM on YouTube now for more: https://bit.ly/2jvAaUD Get more Birmingham news: http://www.wvtm13.com Like us: https://www.facebook.com/WVTM13/ Follow us: https://twitter.com/WVTM13 Instagram: https://www.instagram.com/wvtm13/ https://www.youtube-nocookie.com/embed/4cCEWiVywMQ 141 2023-05-17T00:15:10.000Z 2026-10-22T17:43:38.462Z https://longevityharbor.com/de/watch/4cCEWiVywMQ UAB study examining impact of calorie reduction, intermittent fasting on aging process https://i.ytimg.com/vi/4cCEWiVywMQ/hqdefault.jpg UAB study examining impact of calorie reduction, intermittent fasting on aging process Subscribe to WVTM on YouTube now for more: https://bit.ly/2jvAaUD Get more Birmingham news: http://www.wvtm13.com Like us: https://www.facebook.com/WVTM13/ Follow us: https://twitter.com/WVTM13 Instagram: https://www.instagram.com/wvtm13/ https://www.youtube-nocookie.com/embed/4cCEWiVywMQ 141 2023-05-17T00:15:10.000Z 2026-10-22T17:43:38.462Z https://longevityharbor.com/en/watch/4lb6teUSO-s Biological-age tests: do scores prove better health? https://i.ytimg.com/vi/4lb6teUSO-s/hqdefault.jpg The description says some interventions change selected aging biomarkers, but a younger biological-age score is not yet a validated certificate of broad human age reversal. https://www.youtube-nocookie.com/embed/4lb6teUSO-s 4669 2026-10-06T12:00:12.000Z 2026-10-22T21:17:41.855Z https://longevityharbor.com/de/watch/4lb6teUSO-s Biologische Alters-Tests: Belegen Werte bessere Gesundheit? https://i.ytimg.com/vi/4lb6teUSO-s/hqdefault.jpg Laut Beschreibung verändern manche Maßnahmen ausgewählte Alterns-Biomarker, doch ein jüngerer biologischer Alterswert ist noch kein belegter Nachweis einer umfassenden Verjüngung beim Menschen. https://www.youtube-nocookie.com/embed/4lb6teUSO-s 4669 2026-10-06T12:00:12.000Z 2026-10-22T21:17:41.855Z https://longevityharbor.com/en/watch/4mUF7BXpARs Autophagy, Can You Extend Your Life with Fasting? https://i.ytimg.com/vi/4mUF7BXpARs/hqdefault.jpg Clip from S6 - E7 - The Other Side of Yes with Matt McAlister Matt is currently a PhD student in Biomedical Sciences at the Baylor College of Medicine. He studies aging and longevity with the goal of (eventually) extending healthy human lifespan.(nbd) He has two undergraduate degrees, one in philosophy and one in biochemistry, which along with some serious improv chops as a performer, teacher and coach, helps explain what makes this conversation fascinating! We talk about life lessons from improv, including the power of being wrong and agreeing with someone who tells you that you’re wrong and the secret to staying young forever! (for reals but you’ll have to listen) LinkedIn: https://www.linkedin.com/in/mdmcalister/ Instagram: https://www.instagram.com/matt.d.mcalister/ X: https://x.com/mdMcAlister Facebook: https://www.facebook.com/matt.mcalister We would like to thank our title sponsor for season 6, CoVet. Meet the world's most powerful veterinary AI copilot. CoVet's easy AI scribe writes your records and automates your admin work so you can focus on the things that matter most. Get 15% off your first year with the promo code below. Website: https://www.co.vet Promo details: 15% off first-year annual membership Promo code: co.vet/boston2025 or https://app.co.vet/authorization?campaign=boston2025&signup=true  Thanks for listening to Comedicine! Send is a text to let us know what you think! Instagram @comedicine_comedy Comedicine Facebook Your host, Dr Sarah Boston Dr Sarah Boston is a veterinary surgical oncologist (cancer surgeon for dogs and cats), cancer survivor (ironic, right?), bestselling author, actor and stand up comedian. She is a 2023 graduate of the Humber College Comedy Performance and Writing Program. She is the 2023 recipient of the Tim Sims Encouragement Fund Award, which recognizes and supports promising comedic performers in the early stages of their career She is also the recipient of the Award for Academic Excellence from Humber College because she is a nerd in all https://www.youtube-nocookie.com/embed/4mUF7BXpARs 97 2025-10-20T04:00:05.000Z 2026-10-22T19:32:30.830Z https://longevityharbor.com/de/watch/4mUF7BXpARs Autophagy, Can You Extend Your Life with Fasting? https://i.ytimg.com/vi/4mUF7BXpARs/hqdefault.jpg Clip from S6 - E7 - The Other Side of Yes with Matt McAlister Matt is currently a PhD student in Biomedical Sciences at the Baylor College of Medicine. He studies aging and longevity with the goal of (eventually) extending healthy human lifespan.(nbd) He has two undergraduate degrees, one in philosophy and one in biochemistry, which along with some serious improv chops as a performer, teacher and coach, helps explain what makes this conversation fascinating! We talk about life lessons from improv, including the power of being wrong and agreeing with someone who tells you that you’re wrong and the secret to staying young forever! (for reals but you’ll have to listen) LinkedIn: https://www.linkedin.com/in/mdmcalister/ Instagram: https://www.instagram.com/matt.d.mcalister/ X: https://x.com/mdMcAlister Facebook: https://www.facebook.com/matt.mcalister We would like to thank our title sponsor for season 6, CoVet. Meet the world's most powerful veterinary AI copilot. CoVet's easy AI scribe writes your records and automates your admin work so you can focus on the things that matter most. Get 15% off your first year with the promo code below. Website: https://www.co.vet Promo details: 15% off first-year annual membership Promo code: co.vet/boston2025 or https://app.co.vet/authorization?campaign=boston2025&signup=true  Thanks for listening to Comedicine! Send is a text to let us know what you think! Instagram @comedicine_comedy Comedicine Facebook Your host, Dr Sarah Boston Dr Sarah Boston is a veterinary surgical oncologist (cancer surgeon for dogs and cats), cancer survivor (ironic, right?), bestselling author, actor and stand up comedian. She is a 2023 graduate of the Humber College Comedy Performance and Writing Program. She is the 2023 recipient of the Tim Sims Encouragement Fund Award, which recognizes and supports promising comedic performers in the early stages of their career She is also the recipient of the Award for Academic Excellence from Humber College because she is a nerd in all https://www.youtube-nocookie.com/embed/4mUF7BXpARs 97 2025-10-20T04:00:05.000Z 2026-10-22T19:32:30.830Z https://longevityharbor.com/en/watch/4mcPPhP8G5A Wasserfasten und Longevity https://i.ytimg.com/vi/4mcPPhP8G5A/hqdefault.jpg Herzlich willkommen in unserer Wasserfasten‑Community! https://www.patreon.com/c/profschwarzfastet Ich freue mich sehr, dass Sie hier sind und sich so bewusst mit dem Thema Wasserfasten auseinandersetzen. In diesem Bereich finden Sie alles, was Sie für ein sicheres und wirksames Fasten brauchen: Hintergrundwissen zum Stoffwechsel, praktische Tipps für die 14 Tage, Antworten zu Themen wie Mikrobiom, Glaubern, Sport, Laborwerten nach dem Fasten und vieles mehr. Mein Ziel ist, Sie medizinisch fundiert, aber alltagstauglich zu begleiten – egal ob Sie zum ersten Mal fasten oder bereits Erfahrung haben. Nutzen Sie den Chat gern, um ​ - Fragen zu Ihrer Vorbereitung oder zu konkreten Fastentagen zu stellen, - kurze Rückmeldungen zu Ihrem Verlauf zu geben - und sich gegenseitig zu unterstützen und zu motivieren. Stöbern Sie in den Beiträgen, schreiben Sie Ihre Fragen und Erfahrungen in den Chat – genau daraus lebt diese Gemeinschaft. Entdecken Sie die Kraft des Wasserfastens! Im Onlinekurs „Wasserfasten nach Schwarz“ lernen Sie alles über sicheres Fasten – von Vorbereitung bis Integration in den Alltag. Mit persönlicher Begleitung, wissenschaftlicher Basis und inspirierender Praxis. Als Mitglied "Interessierter" kostenfrei. Jetzt mit dem Code "WASSER" 30% Rabatt auf den ersten Monatsbeitrag oder sogar das erste Jahr https://www.patreon.com/c/profschwarzfastet Liebe Interessierte an dem Fastenkanal auf Patreon, der Fastenchat ist für alle Mitglieder ab Level "Interessierter - Fasteninfo praktisch " zugänglich #longevity #profschwarzfastet #wasserfasten Wasserfasten ist ein starkes Werkzeug im Longevity‑Werkzeugkasten, aber kein alleiniger „Lebenselixier‑Trick“ – die vielversprechendsten Effekte entstehen über Autophagie, Stoffwechselentlastung und die Kombination mit langfristiger Kalorien- und Proteinreduktion. Mechanismen: Warum Fasten alternsrelevant ist Schon 24–48 Stunden Nahrungsverzicht aktivieren in Leber, Gehirn und anderen Geweben Autophagie, also das „Recyclingprogramm“ für geschädigte Zellbestandte https://www.youtube-nocookie.com/embed/4mcPPhP8G5A 139 2026-05-13T11:08:31.000Z 2026-10-22T18:32:09.087Z https://longevityharbor.com/de/watch/4mcPPhP8G5A Wasserfasten und Longevity https://i.ytimg.com/vi/4mcPPhP8G5A/hqdefault.jpg Herzlich willkommen in unserer Wasserfasten‑Community! https://www.patreon.com/c/profschwarzfastet Ich freue mich sehr, dass Sie hier sind und sich so bewusst mit dem Thema Wasserfasten auseinandersetzen. In diesem Bereich finden Sie alles, was Sie für ein sicheres und wirksames Fasten brauchen: Hintergrundwissen zum Stoffwechsel, praktische Tipps für die 14 Tage, Antworten zu Themen wie Mikrobiom, Glaubern, Sport, Laborwerten nach dem Fasten und vieles mehr. Mein Ziel ist, Sie medizinisch fundiert, aber alltagstauglich zu begleiten – egal ob Sie zum ersten Mal fasten oder bereits Erfahrung haben. Nutzen Sie den Chat gern, um ​ - Fragen zu Ihrer Vorbereitung oder zu konkreten Fastentagen zu stellen, - kurze Rückmeldungen zu Ihrem Verlauf zu geben - und sich gegenseitig zu unterstützen und zu motivieren. Stöbern Sie in den Beiträgen, schreiben Sie Ihre Fragen und Erfahrungen in den Chat – genau daraus lebt diese Gemeinschaft. Entdecken Sie die Kraft des Wasserfastens! Im Onlinekurs „Wasserfasten nach Schwarz“ lernen Sie alles über sicheres Fasten – von Vorbereitung bis Integration in den Alltag. Mit persönlicher Begleitung, wissenschaftlicher Basis und inspirierender Praxis. Als Mitglied "Interessierter" kostenfrei. Jetzt mit dem Code "WASSER" 30% Rabatt auf den ersten Monatsbeitrag oder sogar das erste Jahr https://www.patreon.com/c/profschwarzfastet Liebe Interessierte an dem Fastenkanal auf Patreon, der Fastenchat ist für alle Mitglieder ab Level "Interessierter - Fasteninfo praktisch " zugänglich #longevity #profschwarzfastet #wasserfasten Wasserfasten ist ein starkes Werkzeug im Longevity‑Werkzeugkasten, aber kein alleiniger „Lebenselixier‑Trick“ – die vielversprechendsten Effekte entstehen über Autophagie, Stoffwechselentlastung und die Kombination mit langfristiger Kalorien- und Proteinreduktion. Mechanismen: Warum Fasten alternsrelevant ist Schon 24–48 Stunden Nahrungsverzicht aktivieren in Leber, Gehirn und anderen Geweben Autophagie, also das „Recyclingprogramm“ für geschädigte Zellbestandte https://www.youtube-nocookie.com/embed/4mcPPhP8G5A 139 2026-05-13T11:08:31.000Z 2026-10-22T18:32:09.087Z https://longevityharbor.com/en/watch/4pM0KEYKCaI Live Longer with Intermittent Fasting But... | Educational Video | Layne Norton PhD https://i.ytimg.com/vi/4pM0KEYKCaI/hqdefault.jpg Citations- IF + Probiotic Study: https://pubmed.ncbi.nlm.nih.gov/39143654/ IF Scoping Review: https://pubmed.ncbi.nlm.nih.gov/38276554/ Get my research review REPS: biolayne.com/REPS Get my new nutrition coaching app, Carbon Diet Coach: http://onelink.to/9h4d62 My research based supplements: http://www.outworknutrition.com Get my books on how to lose fat: http://www.biolaynestore.com Take my online course "The Science of Nutrition": https://chfi.click/laynenorton_online Get Custom Workouts by me for $12.99/month: https://biolayne.com/workout-builder/ http://www.facebook.com/laynenorton http://www.twitter.com/biolayne http://www.instagram.com/biolayne https://www.youtube-nocookie.com/embed/4pM0KEYKCaI 402 2024-11-27T20:00:02.000Z 2026-10-22T17:43:38.461Z https://longevityharbor.com/de/watch/4pM0KEYKCaI Live Longer with Intermittent Fasting But... | Educational Video | Layne Norton PhD https://i.ytimg.com/vi/4pM0KEYKCaI/hqdefault.jpg Citations- IF + Probiotic Study: https://pubmed.ncbi.nlm.nih.gov/39143654/ IF Scoping Review: https://pubmed.ncbi.nlm.nih.gov/38276554/ Get my research review REPS: biolayne.com/REPS Get my new nutrition coaching app, Carbon Diet Coach: http://onelink.to/9h4d62 My research based supplements: http://www.outworknutrition.com Get my books on how to lose fat: http://www.biolaynestore.com Take my online course "The Science of Nutrition": https://chfi.click/laynenorton_online Get Custom Workouts by me for $12.99/month: https://biolayne.com/workout-builder/ http://www.facebook.com/laynenorton http://www.twitter.com/biolayne http://www.instagram.com/biolayne https://www.youtube-nocookie.com/embed/4pM0KEYKCaI 402 2024-11-27T20:00:02.000Z 2026-10-22T17:43:38.461Z https://longevityharbor.com/en/watch/50_mJBuxY1A The Role of Exercise in Healthy Aging by Dr. Jill Barnes https://i.ytimg.com/vi/50_mJBuxY1A/hqdefault.jpg Dr. Jill Barnes discussed exercise and a preventive measure for Alzheimer's disease at the 2017 Wisconsin Alzheimer's Disease Research Center Fall Lecture - "The Science Behind Alzheimer's Disease Prevention and Brain Health." https://www.youtube-nocookie.com/embed/50_mJBuxY1A 1249 2017-10-26T16:13:10.000Z 2026-10-22T17:43:36.911Z https://longevityharbor.com/de/watch/50_mJBuxY1A The Role of Exercise in Healthy Aging by Dr. Jill Barnes https://i.ytimg.com/vi/50_mJBuxY1A/hqdefault.jpg Dr. Jill Barnes discussed exercise and a preventive measure for Alzheimer's disease at the 2017 Wisconsin Alzheimer's Disease Research Center Fall Lecture - "The Science Behind Alzheimer's Disease Prevention and Brain Health." https://www.youtube-nocookie.com/embed/50_mJBuxY1A 1249 2017-10-26T16:13:10.000Z 2026-10-22T17:43:36.911Z https://longevityharbor.com/en/watch/54QkLFayAnQ 1098: Intermittent Fasting vs. Calorie Restriction (Winner Announced) (TT) https://i.ytimg.com/vi/54QkLFayAnQ/hqdefault.jpg A lot of people may not know this about me, but deep down I'm a big-time skeptic when it comes to a lot of research studies... Don't get me wrong, I'm reading the research and science behind them daily, but the fact is that many of them are "paid for" or funded by groups that have an agenda... And other studies have such a small sample size that the data isn't really clinically significant, yet the media makes it out to be this "groundbreaking" study! But, I make sure to never let the bad crowd out some really great studies and I think this initial research (although still small) gave us some insight on how intermittent fasting (IF) stacks up versus continuous daily calorie reduction... Check out today's #CabralConcept 1098 to discover the winner of the debate of whether intermittent fasting is better than calorie reduction for weight loss and overall health - Enjoy the show! - - -   Show Notes & Resources: http://StephenCabral.com/1098 (http://stephencabral.com/1098) - - - Dr. Cabral's New Book, The Rain Barrel Effect https://amzn.to/2H0W7Ge - - - Join the Community & Get Your Questions Answered: http://CabralSupportGroup.com (http://cabralsupportgroup.com/) - - -   Dr. Cabral’s Most Popular Supplements: ＞ “The Dr. Cabral Daily Protocol (http://stephencabral.com/store/product/dr-cabral-daily-protocol-powder/) ” (This is what Dr. Cabral does every day!) - - - ＞ Dr. Cabral Detox (http://drcabraldetox.com/)   (The fastest way to get well, lose weight, and feel great!) - - - ＞ Daily Nutritional Support Shake (https://stephencabral.com/store/product/daily-nutritional-support/)   (#1 “All-in-One recommendation in my practice) - - - ＞ Daily Fruit & Vegetables Blend (http://stephencabral.com/store/product/daily-fruit-vegetables-blend/)   (22 organic fruit & vegetables “greens powder”) - - - ＞ CBD Oil (http://stephencabral.com/store/product/organic-cbd-oil/)   (Full-spectrum, 3rd part-tested & organically grown) - - - ＞ Cand https://www.youtube-nocookie.com/embed/54QkLFayAnQ 1597 2024-02-20T02:59:38.000Z 2026-10-22T19:54:18.106Z https://longevityharbor.com/de/watch/54QkLFayAnQ 1098: Intermittent Fasting vs. Calorie Restriction (Winner Announced) (TT) https://i.ytimg.com/vi/54QkLFayAnQ/hqdefault.jpg A lot of people may not know this about me, but deep down I'm a big-time skeptic when it comes to a lot of research studies... Don't get me wrong, I'm reading the research and science behind them daily, but the fact is that many of them are "paid for" or funded by groups that have an agenda... And other studies have such a small sample size that the data isn't really clinically significant, yet the media makes it out to be this "groundbreaking" study! But, I make sure to never let the bad crowd out some really great studies and I think this initial research (although still small) gave us some insight on how intermittent fasting (IF) stacks up versus continuous daily calorie reduction... Check out today's #CabralConcept 1098 to discover the winner of the debate of whether intermittent fasting is better than calorie reduction for weight loss and overall health - Enjoy the show! - - -   Show Notes & Resources: http://StephenCabral.com/1098 (http://stephencabral.com/1098) - - - Dr. Cabral's New Book, The Rain Barrel Effect https://amzn.to/2H0W7Ge - - - Join the Community & Get Your Questions Answered: http://CabralSupportGroup.com (http://cabralsupportgroup.com/) - - -   Dr. Cabral’s Most Popular Supplements: ＞ “The Dr. Cabral Daily Protocol (http://stephencabral.com/store/product/dr-cabral-daily-protocol-powder/) ” (This is what Dr. Cabral does every day!) - - - ＞ Dr. Cabral Detox (http://drcabraldetox.com/)   (The fastest way to get well, lose weight, and feel great!) - - - ＞ Daily Nutritional Support Shake (https://stephencabral.com/store/product/daily-nutritional-support/)   (#1 “All-in-One recommendation in my practice) - - - ＞ Daily Fruit & Vegetables Blend (http://stephencabral.com/store/product/daily-fruit-vegetables-blend/)   (22 organic fruit & vegetables “greens powder”) - - - ＞ CBD Oil (http://stephencabral.com/store/product/organic-cbd-oil/)   (Full-spectrum, 3rd part-tested & organically grown) - - - ＞ Cand https://www.youtube-nocookie.com/embed/54QkLFayAnQ 1597 2024-02-20T02:59:38.000Z 2026-10-22T19:54:18.106Z https://longevityharbor.com/en/watch/58fHhbcF4l8 Podcast - The Rich Roll Podcast | In Conversation with Dr. Valter Longo https://i.ytimg.com/vi/58fHhbcF4l8/hqdefault.jpg What if fasting could help the body regenerate itself? Dr. Valter Longo explains how cycles of fasting mimicking diet activate bone marrow stem cells to regenerate the immune system and restore normal insulin production in the pancreas, results that could transform approaches to cancer therapy and diabetes treatment. Watch the full episode at the following link: https://www.youtube.com/watch?v=ZwdhdevxlRg (link in bio for Instagram) @richroll #ProfValterLongo #longevitydiet #fastingmimickingdiet #createcuresfoundation #TheRichRollPodcast #RichRoll #therapeuticfasting #regeneration #stemcells #diabetes #cancerresearch #healthyaging #nutritionscience https://www.youtube-nocookie.com/embed/58fHhbcF4l8 91 2025-10-23T13:00:09.000Z 2026-10-22T18:54:06.998Z https://longevityharbor.com/de/watch/58fHhbcF4l8 Podcast - The Rich Roll Podcast | In Conversation with Dr. Valter Longo https://i.ytimg.com/vi/58fHhbcF4l8/hqdefault.jpg What if fasting could help the body regenerate itself? Dr. Valter Longo explains how cycles of fasting mimicking diet activate bone marrow stem cells to regenerate the immune system and restore normal insulin production in the pancreas, results that could transform approaches to cancer therapy and diabetes treatment. Watch the full episode at the following link: https://www.youtube.com/watch?v=ZwdhdevxlRg (link in bio for Instagram) @richroll #ProfValterLongo #longevitydiet #fastingmimickingdiet #createcuresfoundation #TheRichRollPodcast #RichRoll #therapeuticfasting #regeneration #stemcells #diabetes #cancerresearch #healthyaging #nutritionscience https://www.youtube-nocookie.com/embed/58fHhbcF4l8 91 2025-10-23T13:00:09.000Z 2026-10-22T18:54:06.998Z https://longevityharbor.com/en/watch/5BOm1QPlb80 Talk on rapamycin, mTOR and aging in lab models, companion animals and humans https://i.ytimg.com/vi/5BOm1QPlb80/hqdefault.jpg The description announces a talk by Dr. Matt Kaeberlein on how rapamycin and the mTOR pathway became central to aging research, including what is and is not known about healthy aging in people. https://www.youtube-nocookie.com/embed/5BOm1QPlb80 4800 2026-04-20T19:30:01.000Z 2026-10-23T01:30:10.368Z https://longevityharbor.com/de/watch/5BOm1QPlb80 Vortrag zu Rapamycin, mTOR und Altern in Labormodellen, Begleittieren und Menschen https://i.ytimg.com/vi/5BOm1QPlb80/hqdefault.jpg Die Beschreibung kündigt einen Vortrag von Dr. Matt Kaeberlein dazu an, wie Rapamycin und der mTOR-Signalweg zentral für die Alternsforschung wurden, einschließlich dessen, was über gesundes Altern beim Menschen bekannt ist und was nicht. https://www.youtube-nocookie.com/embed/5BOm1QPlb80 4800 2026-04-20T19:30:01.000Z 2026-10-23T01:30:10.368Z https://longevityharbor.com/en/watch/5BfHMVgvUQo Rapamycin, mTOR & Autophagy: More Anti Aging Concepts (David Sinclair LIFESPAN - Part 3) https://i.ytimg.com/vi/5BfHMVgvUQo/hqdefault.jpg Want to learn one of the basics of heart attack & stroke prevention... for free? Get free access to the CV inflammation course by completing this form: https://care.prevmedhealth.com/FreeOnlineCourse. Learn how to predict & prevent heart attack & stroke: https://care.prevmedhealth.com/How-To-Predict-a-Heart-Attack. Learn how to reduce & reverse arterial plaque: https://care.prevmedhealth.com/How-To-Reverse-Arterial-Plaque. -- ABOUT THIS VIDEO: This is part 3 of our series on David Sinclair's new book, "Lifespan: Why We Age and Why We Don't Have To." We'll talk about 3 concepts—rapamycin, mTOR, autophagy. Rapamycin (an antibiotic) inhibits mTOR (a protein). mTOR inhibits autophagy. Autophagy is a natural process by which the body eliminates unnecessary components (like dead mitochondria). So, does rapamycin have an effect on aging and longevity? That's what we'll discuss in the video. Membership Area Registration Link - https://bit.ly/PrevMembership ABOUT DR. BREWER: Dr. Brewer started as an Emergency Doctor. After seeing too many preventable heart attacks, he went to Johns Hopkins to learn Preventive Medicine. While there, he went on the run the post-graduate training program (residency) in Preventive Medicine. From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has close to 1,000 primary care/prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack and stroke prevention clinic. At PrevMed, we focus on heart attack, stroke, and cognitive decline. We serve patients who have already experienced an event as well as those who have not developed a diagnosis or event. Dr. Brewer provides services via telemedicine or in person if you're in the Lexington, KY area. We find a lot of undiagnosed prediabetes or insulin resistance. Treating unrecognized risk factors like prediabetes allows r https://www.youtube-nocookie.com/embed/5BfHMVgvUQo 434 2019-10-24T15:00:00.000Z 2026-10-22T17:43:41.052Z https://longevityharbor.com/de/watch/5BfHMVgvUQo Rapamycin, mTOR & Autophagy: More Anti Aging Concepts (David Sinclair LIFESPAN - Part 3) https://i.ytimg.com/vi/5BfHMVgvUQo/hqdefault.jpg Want to learn one of the basics of heart attack & stroke prevention... for free? Get free access to the CV inflammation course by completing this form: https://care.prevmedhealth.com/FreeOnlineCourse. Learn how to predict & prevent heart attack & stroke: https://care.prevmedhealth.com/How-To-Predict-a-Heart-Attack. Learn how to reduce & reverse arterial plaque: https://care.prevmedhealth.com/How-To-Reverse-Arterial-Plaque. -- ABOUT THIS VIDEO: This is part 3 of our series on David Sinclair's new book, "Lifespan: Why We Age and Why We Don't Have To." We'll talk about 3 concepts—rapamycin, mTOR, autophagy. Rapamycin (an antibiotic) inhibits mTOR (a protein). mTOR inhibits autophagy. Autophagy is a natural process by which the body eliminates unnecessary components (like dead mitochondria). So, does rapamycin have an effect on aging and longevity? That's what we'll discuss in the video. Membership Area Registration Link - https://bit.ly/PrevMembership ABOUT DR. BREWER: Dr. Brewer started as an Emergency Doctor. After seeing too many preventable heart attacks, he went to Johns Hopkins to learn Preventive Medicine. While there, he went on the run the post-graduate training program (residency) in Preventive Medicine. From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has close to 1,000 primary care/prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack and stroke prevention clinic. At PrevMed, we focus on heart attack, stroke, and cognitive decline. We serve patients who have already experienced an event as well as those who have not developed a diagnosis or event. Dr. Brewer provides services via telemedicine or in person if you're in the Lexington, KY area. We find a lot of undiagnosed prediabetes or insulin resistance. Treating unrecognized risk factors like prediabetes allows r https://www.youtube-nocookie.com/embed/5BfHMVgvUQo 434 2019-10-24T15:00:00.000Z 2026-10-22T17:43:41.052Z https://longevityharbor.com/en/watch/5ExbVJdH8Mg Epigenetic clocks explained: methylation age is not proof of reversed aging https://i.ytimg.com/vi/5ExbVJdH8Mg/hqdefault.jpg In this video description, Todd Vande Hei presents epigenetic clocks and DNA methylation as emerging tools that estimate biological age, while stressing that a lower methylation age score does not mean aging has been reversed. https://www.youtube-nocookie.com/embed/5ExbVJdH8Mg 705 2026-03-19T13:00:00.000Z 2026-10-23T01:59:54.871Z https://longevityharbor.com/de/watch/5ExbVJdH8Mg Epigenetische Uhren erklärt: Methylierungsalter ist kein Beweis für rückwärts gerichtetes Altern https://i.ytimg.com/vi/5ExbVJdH8Mg/hqdefault.jpg In dieser Videobeschreibung stellt Todd Vande Hei epigenetische Uhren und DNA-Methylierung als neue Werkzeuge vor, die das biologische Alter schätzen sollen, und betont zugleich, dass ein niedrigerer Methylierungsalter-Wert nicht bedeutet, dass das Altern rückgängig gemacht wurde. https://www.youtube-nocookie.com/embed/5ExbVJdH8Mg 705 2026-03-19T13:00:00.000Z 2026-10-23T01:59:54.871Z https://longevityharbor.com/en/watch/5KnDmHtqQzI Video description: 5-day fasting-mimicking diet and claimed longevity effects https://i.ytimg.com/vi/5KnDmHtqQzI/hqdefault.jpg The description presents the fasting-mimicking diet as a 5-day, calorie-restricted, plant-based protocol and cites a 2017 randomized trial in which three cycles reduced visceral fat, blood pressure, IGF-1 and CRP. It is described as an adjunct, not a weight-loss shortcut. https://www.youtube-nocookie.com/embed/5KnDmHtqQzI 543 2026-08-14T12:00:05.000Z 2026-10-22T23:01:46.323Z https://longevityharbor.com/de/watch/5KnDmHtqQzI Videobeschreibung: 5-Tage-Fasten-Mimik-Diät und behauptete Langlebigkeitseffekte https://i.ytimg.com/vi/5KnDmHtqQzI/hqdefault.jpg Die Beschreibung stellt die Fasten-Mimik-Diät als 5-tägiges, kalorienreduziertes, pflanzliches Protokoll vor und nennt eine randomisierte Studie von 2017, in der drei Zyklen viszerales Fett, Blutdruck, IGF-1 und CRP senkten. Sie wird als Ergänzung, nicht als Abnehm-Abkürzung beschrieben. https://www.youtube-nocookie.com/embed/5KnDmHtqQzI 543 2026-08-14T12:00:05.000Z 2026-10-22T23:01:46.323Z https://longevityharbor.com/en/watch/5LcgovlTxIM Single cell epigenetic clocks & applications - Alex Trapp https://i.ytimg.com/vi/5LcgovlTxIM/hqdefault.jpg In this video we take a deep dive into the recent publication in Nature Aging, "Profiling epigenetic age in single cells", with the lead author of the paper Alex Trapp! We discuss the difference between biological and chronological age, how epigenetic clocks work, the challenges of measuring the age of a single cell and then scAge and its applications. Paper Link: Trapp, A., Kerepesi, C. & Gladyshev, V.N. Profiling epigenetic age in single cells. Nat Aging 1, 1189–1201 (2021). https://doi.org/10.1038/s43587-021-00134-3 Find Alex on Twitter - https://twitter.com/AlexandreTrapp Find me on Twitter - https://twitter.com/EleanorSheekey Support the channel through PayPal - https://paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB through Patreon - https://www.patreon.com/TheSheekeyScienceShow Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com https://www.youtube-nocookie.com/embed/5LcgovlTxIM 1097 2022-01-19T16:01:41.000Z 2026-10-22T17:43:35.319Z https://longevityharbor.com/de/watch/5LcgovlTxIM Single cell epigenetic clocks & applications - Alex Trapp https://i.ytimg.com/vi/5LcgovlTxIM/hqdefault.jpg In this video we take a deep dive into the recent publication in Nature Aging, "Profiling epigenetic age in single cells", with the lead author of the paper Alex Trapp! We discuss the difference between biological and chronological age, how epigenetic clocks work, the challenges of measuring the age of a single cell and then scAge and its applications. Paper Link: Trapp, A., Kerepesi, C. & Gladyshev, V.N. Profiling epigenetic age in single cells. Nat Aging 1, 1189–1201 (2021). https://doi.org/10.1038/s43587-021-00134-3 Find Alex on Twitter - https://twitter.com/AlexandreTrapp Find me on Twitter - https://twitter.com/EleanorSheekey Support the channel through PayPal - https://paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB through Patreon - https://www.patreon.com/TheSheekeyScienceShow Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com https://www.youtube-nocookie.com/embed/5LcgovlTxIM 1097 2022-01-19T16:01:41.000Z 2026-10-22T17:43:35.319Z https://longevityharbor.com/en/watch/5N4C_XRXKvQ Senolytics & Stem Cells: How to Live to 120 & Stay Healthy https://i.ytimg.com/vi/5N4C_XRXKvQ/hqdefault.jpg In this episode of our Longevity Series (Part 4), stem cell scientist and herbalist Christian Drapeau breaks down the science of senolytics—compounds that help eliminate aging, damaged cells and rejuvenate tissues. ► Boost your body's natural repair system! Try STEMREGEN® Release 👉https://www.stemregen.co/products/release 🧬 What You’ll Learn in This Video: ✅ The role of stem cells in tissue repair and longevity ✅ How senescent cells contribute to aging and disease (Parkinson’s, osteoporosis, etc.) ✅ The best senolytic compounds (like fisetin from strawberries and smoke bush) ✅ How to use biohacking strategies to optimize anti-aging and cellular rejuvenation ✅ How to cycle senolytics for maximum benefit 🌱 Natural Senolytics Mentioned: 🔸 Fisetin – Found in strawberries & smoke bush 🔸 Piperlongumine – Extracted from long pepper 🔸 Other plant-based compounds targeting senescent cells By strategically using senolytics for just a few days each month, you can help your body remove damaged cells, regenerate with stem cells, and optimize for longevity and anti-aging. 🔔 Subscribe for More Biohacking & Longevity Tips! 💬 What do you think about senolytics? Have you tried any natural compounds for anti-aging? Drop a comment below! #Senolytics #StemCellTherapy #Longevity #AntiAging #Biohacking #Fisetin #StemCells #HealthyAging #CellRejuvenation #LifespanExtension #ReverseAging https://www.youtube-nocookie.com/embed/5N4C_XRXKvQ 178 2025-03-28T20:37:51.000Z 2026-10-22T18:43:12.606Z https://longevityharbor.com/de/watch/5N4C_XRXKvQ Senolytics & Stem Cells: How to Live to 120 & Stay Healthy https://i.ytimg.com/vi/5N4C_XRXKvQ/hqdefault.jpg In this episode of our Longevity Series (Part 4), stem cell scientist and herbalist Christian Drapeau breaks down the science of senolytics—compounds that help eliminate aging, damaged cells and rejuvenate tissues. ► Boost your body's natural repair system! Try STEMREGEN® Release 👉https://www.stemregen.co/products/release 🧬 What You’ll Learn in This Video: ✅ The role of stem cells in tissue repair and longevity ✅ How senescent cells contribute to aging and disease (Parkinson’s, osteoporosis, etc.) ✅ The best senolytic compounds (like fisetin from strawberries and smoke bush) ✅ How to use biohacking strategies to optimize anti-aging and cellular rejuvenation ✅ How to cycle senolytics for maximum benefit 🌱 Natural Senolytics Mentioned: 🔸 Fisetin – Found in strawberries & smoke bush 🔸 Piperlongumine – Extracted from long pepper 🔸 Other plant-based compounds targeting senescent cells By strategically using senolytics for just a few days each month, you can help your body remove damaged cells, regenerate with stem cells, and optimize for longevity and anti-aging. 🔔 Subscribe for More Biohacking & Longevity Tips! 💬 What do you think about senolytics? Have you tried any natural compounds for anti-aging? Drop a comment below! #Senolytics #StemCellTherapy #Longevity #AntiAging #Biohacking #Fisetin #StemCells #HealthyAging #CellRejuvenation #LifespanExtension #ReverseAging https://www.youtube-nocookie.com/embed/5N4C_XRXKvQ 178 2025-03-28T20:37:51.000Z 2026-10-22T18:43:12.606Z https://longevityharbor.com/en/watch/5Nq0OYLcNE0 💊NMN Anti-Aging Supplement 💊 WHY I DON'T TAKE IT @DrDrayzday https://i.ytimg.com/vi/5Nq0OYLcNE0/hqdefault.jpg 💊NMN Anti-Aging Supplement 💊 WHY I DON'T TAKE IT @DrDrayzday on NMN supplement benefits for anti-aging. Is taking NMN supplements beneficial? In this video I review the research on NMN as an anti-aging supplement and discuss the FDA ban on NMN supplements in the US. #antiaging #supplements #nmn Nicotinamide supplement for skin https://youtu.be/Y0QDCgSWCx0 Skin benefits of Heliocare (polypodium) https://youtu.be/A3xs7Ox0tL4 The worst supplements for skin https://youtu.be/vBQBjq4sA8U Alpha lipoic acid for skin https://youtu.be/6LBaqYNIxnI DIM supplements for skin https://youtu.be/rO9v3vC2cEc 💊References Nadeeshani H, Li J, Ying T, Zhang B, Lu J. Nicotinamide mononucleotide (NMN) as an anti-aging health product - Promises and safety concerns. J Adv Res. 2021 Aug 11;37:267-278. doi: 10.1016/j.jare.2021.08.003. PMID: 35499054; PMCID: PMC9039735. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021 Jul 8;18(1):54. doi: 10.1186/s12970-021-00442-4. PMID: 34238308; PMCID: PMC8265078. Yoshino M, Yoshino J, Kayser BD, Patti GJ, Franczyk MP, Mills KF, Sindelar M, Pietka T, Patterson BW, Imai SI, Klein S. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021 Jun 11;372(6547):1224-1229. doi: 10.1126/science.abe9985. Epub 2021 Apr 22. PMID: 33888596; PMCID: PMC8550608. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022 Feb 11;14(4):755. doi: 10.3390/nu14040755. PMID: 35215405; PMCID: PMC8877443. Okabe K, Yaku K, Uchida Y, Fukamizu Y, Sato T, Sakurai T, Tobe K, Nakagawa T. Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects. Front Nut https://www.youtube-nocookie.com/embed/5Nq0OYLcNE0 1004 2023-02-02T17:00:07.000Z 2026-10-23T00:51:10.509Z https://longevityharbor.com/de/watch/5Nq0OYLcNE0 💊NMN Anti-Aging Supplement 💊 WHY I DON'T TAKE IT @DrDrayzday https://i.ytimg.com/vi/5Nq0OYLcNE0/hqdefault.jpg 💊NMN Anti-Aging Supplement 💊 WHY I DON'T TAKE IT @DrDrayzday on NMN supplement benefits for anti-aging. Is taking NMN supplements beneficial? In this video I review the research on NMN as an anti-aging supplement and discuss the FDA ban on NMN supplements in the US. #antiaging #supplements #nmn Nicotinamide supplement for skin https://youtu.be/Y0QDCgSWCx0 Skin benefits of Heliocare (polypodium) https://youtu.be/A3xs7Ox0tL4 The worst supplements for skin https://youtu.be/vBQBjq4sA8U Alpha lipoic acid for skin https://youtu.be/6LBaqYNIxnI DIM supplements for skin https://youtu.be/rO9v3vC2cEc 💊References Nadeeshani H, Li J, Ying T, Zhang B, Lu J. Nicotinamide mononucleotide (NMN) as an anti-aging health product - Promises and safety concerns. J Adv Res. 2021 Aug 11;37:267-278. doi: 10.1016/j.jare.2021.08.003. PMID: 35499054; PMCID: PMC9039735. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021 Jul 8;18(1):54. doi: 10.1186/s12970-021-00442-4. PMID: 34238308; PMCID: PMC8265078. Yoshino M, Yoshino J, Kayser BD, Patti GJ, Franczyk MP, Mills KF, Sindelar M, Pietka T, Patterson BW, Imai SI, Klein S. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021 Jun 11;372(6547):1224-1229. doi: 10.1126/science.abe9985. Epub 2021 Apr 22. PMID: 33888596; PMCID: PMC8550608. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022 Feb 11;14(4):755. doi: 10.3390/nu14040755. PMID: 35215405; PMCID: PMC8877443. Okabe K, Yaku K, Uchida Y, Fukamizu Y, Sato T, Sakurai T, Tobe K, Nakagawa T. Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects. Front Nut https://www.youtube-nocookie.com/embed/5Nq0OYLcNE0 1004 2023-02-02T17:00:07.000Z 2026-10-23T00:51:10.509Z https://longevityharbor.com/en/watch/5SGSoEtyhHw Boost Your Bone Density with These 6 Life-Changing Tips https://i.ytimg.com/vi/5SGSoEtyhHw/hqdefault.jpg In this informative video, we delve into effective strategies to increase your bone density and promote overall bone health. Whether you're looking to strengthen your bones as you age or want to prevent osteoporosis, we've got you covered! 🔍 What You'll Learn: ⭐The importance of bone density and its impact on health ⭐Nutritional tips for bone-strengthening foods ⭐Effective exercises to boost bone density ⭐Lifestyle changes that promote healthy bones ⭐Supplements: What you need to know Join us as we explore practical advice from experts and share easy-to-follow routines that can make a significant difference. Don’t forget to like, subscribe, and hit the notification bell for more health tips! 📅 Follow along for weekly updates! #bonehealth #osteoporosis #healthyliving #fitness #nutrition #bonedensity #wellness #exercise #diet #strongbones #healthtips #lifestylechanges #supplements ☆Daily Steps video:https://www.youtube.com/watch?v=wFGVO7n5r6E ☆Calcium Supplements video: https://www.youtube.com/watch?v=hFjOddxSmv4&t=17s ☆Magnesium video: https://www.youtube.com/watch?v=97y5gQQ3gTA Talking With Docs MERCH: https://www.spreadshirt.ca/shop/design/talking+with+docs+mens+premium+hoodie-D659bf53681f7a13c0f68ca03?sellable=GBZzyVJROjFjYgAR4J74-20-22 Donate To Oakville Hospital: https://donate.oakvillehospitalfoundation.com/ui/waystogive/donations/start Tiktok: https://vm.tiktok.com/ZMFtY2JQ7 Instagram: https://instagram.com/talkingwithdocs?igshid=YmMyMTA2M2Y= Facebook: https://www.facebook.com/profile.php?id=100066771782727&mibextid=LQQJ4d Twitter: https://twitter.com/talkingwithdocs?s=21&t=HhS0GbSwmQ5McMJMial5Jg Please see the complete user agreement at talkingwithdocs.com Medical emergency Do NOT use the Video for medical emergencies. If you have a medical emergency, call a physician or qualified healthcare provider, or CALL 911 immediately. Under no circumstances should you attempt self-treatment based on anything you have seen or read on the Video. General information is not medica https://www.youtube-nocookie.com/embed/5SGSoEtyhHw 1038 2024-11-03T19:37:23.000Z 2026-10-22T19:54:15.452Z https://longevityharbor.com/de/watch/5SGSoEtyhHw Boost Your Bone Density with These 6 Life-Changing Tips https://i.ytimg.com/vi/5SGSoEtyhHw/hqdefault.jpg In this informative video, we delve into effective strategies to increase your bone density and promote overall bone health. Whether you're looking to strengthen your bones as you age or want to prevent osteoporosis, we've got you covered! 🔍 What You'll Learn: ⭐The importance of bone density and its impact on health ⭐Nutritional tips for bone-strengthening foods ⭐Effective exercises to boost bone density ⭐Lifestyle changes that promote healthy bones ⭐Supplements: What you need to know Join us as we explore practical advice from experts and share easy-to-follow routines that can make a significant difference. Don’t forget to like, subscribe, and hit the notification bell for more health tips! 📅 Follow along for weekly updates! #bonehealth #osteoporosis #healthyliving #fitness #nutrition #bonedensity #wellness #exercise #diet #strongbones #healthtips #lifestylechanges #supplements ☆Daily Steps video:https://www.youtube.com/watch?v=wFGVO7n5r6E ☆Calcium Supplements video: https://www.youtube.com/watch?v=hFjOddxSmv4&t=17s ☆Magnesium video: https://www.youtube.com/watch?v=97y5gQQ3gTA Talking With Docs MERCH: https://www.spreadshirt.ca/shop/design/talking+with+docs+mens+premium+hoodie-D659bf53681f7a13c0f68ca03?sellable=GBZzyVJROjFjYgAR4J74-20-22 Donate To Oakville Hospital: https://donate.oakvillehospitalfoundation.com/ui/waystogive/donations/start Tiktok: https://vm.tiktok.com/ZMFtY2JQ7 Instagram: https://instagram.com/talkingwithdocs?igshid=YmMyMTA2M2Y= Facebook: https://www.facebook.com/profile.php?id=100066771782727&mibextid=LQQJ4d Twitter: https://twitter.com/talkingwithdocs?s=21&t=HhS0GbSwmQ5McMJMial5Jg Please see the complete user agreement at talkingwithdocs.com Medical emergency Do NOT use the Video for medical emergencies. If you have a medical emergency, call a physician or qualified healthcare provider, or CALL 911 immediately. Under no circumstances should you attempt self-treatment based on anything you have seen or read on the Video. General information is not medica https://www.youtube-nocookie.com/embed/5SGSoEtyhHw 1038 2024-11-03T19:37:23.000Z 2026-10-22T19:54:15.452Z https://longevityharbor.com/en/watch/5V1jr4nHWgk The Best Way to Build Muscle After 50: A Science-Backed Roadmap https://i.ytimg.com/vi/5V1jr4nHWgk/hqdefault.jpg Is it really possible to build muscle after 50? Dr. Gabrielle Lyon explains why muscle is your body's ultimate organ of longevity and reveals the absolute best way to build strength at any age. We dive deep into the importance of building healthy skeletal muscle mass, emphasizing that it's never too late to start. We explore the nuances of muscle growth and muscle adaptation, particularly through strength training and resistance training. This conversation highlights how these practices are essential for combating sarcopenia and promoting healthy aging. Discover the groundbreaking science of "muscle-centric medicine" with Dr. Gabrielle Lyon and Dr. Mark Hyman. In this episode, we dive deep into why skeletal muscle is crucial for your metabolic health, immune function, and preventing insulin resistance. You'll learn exactly why it is never too late to start resistance training and how avoiding sedentary habits can drastically transform your trajectory of healthy aging. We also break down the practical, actionable steps you need to take right now. From understanding "high ground activity" and mastering the right workout intensity, to the precise amount of protein you should eat (and when to eat it) to overcome anabolic resistance. Whether you are an advanced lifter or stepping into the gym for the first time, this guide provides a clear, science-backed roadmap to staying forever strong. Get my FREE guide 3 Steps to Reverse Aging when you sign up for my weekly health picks 👉 https://bit.ly/IncreaseHealthspan View Show Notes From This Episode: https://https://bit.ly/ep-947 This episode is brought to you by Rupa Health, Beekeepers Naturals, Thrive Market, and Fatty15. Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at https://RupaHealth.com. Head to https://BeekeepersNaturals.com/HYMAN and use the code ‘HYMAN’ to get 20% off sitewide. Head over to https://ThriveMarket.com/Hyman today to receive 30% off your first order and a free gift u https://www.youtube-nocookie.com/embed/5V1jr4nHWgk 4388 2024-09-11T10:00:06.000Z 2026-10-22T18:32:08.302Z https://longevityharbor.com/de/watch/5V1jr4nHWgk The Best Way to Build Muscle After 50: A Science-Backed Roadmap https://i.ytimg.com/vi/5V1jr4nHWgk/hqdefault.jpg Is it really possible to build muscle after 50? Dr. Gabrielle Lyon explains why muscle is your body's ultimate organ of longevity and reveals the absolute best way to build strength at any age. We dive deep into the importance of building healthy skeletal muscle mass, emphasizing that it's never too late to start. We explore the nuances of muscle growth and muscle adaptation, particularly through strength training and resistance training. This conversation highlights how these practices are essential for combating sarcopenia and promoting healthy aging. Discover the groundbreaking science of "muscle-centric medicine" with Dr. Gabrielle Lyon and Dr. Mark Hyman. In this episode, we dive deep into why skeletal muscle is crucial for your metabolic health, immune function, and preventing insulin resistance. You'll learn exactly why it is never too late to start resistance training and how avoiding sedentary habits can drastically transform your trajectory of healthy aging. We also break down the practical, actionable steps you need to take right now. From understanding "high ground activity" and mastering the right workout intensity, to the precise amount of protein you should eat (and when to eat it) to overcome anabolic resistance. Whether you are an advanced lifter or stepping into the gym for the first time, this guide provides a clear, science-backed roadmap to staying forever strong. Get my FREE guide 3 Steps to Reverse Aging when you sign up for my weekly health picks 👉 https://bit.ly/IncreaseHealthspan View Show Notes From This Episode: https://https://bit.ly/ep-947 This episode is brought to you by Rupa Health, Beekeepers Naturals, Thrive Market, and Fatty15. Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at https://RupaHealth.com. Head to https://BeekeepersNaturals.com/HYMAN and use the code ‘HYMAN’ to get 20% off sitewide. Head over to https://ThriveMarket.com/Hyman today to receive 30% off your first order and a free gift u https://www.youtube-nocookie.com/embed/5V1jr4nHWgk 4388 2024-09-11T10:00:06.000Z 2026-10-22T18:32:08.302Z https://longevityharbor.com/en/watch/5VW27IfWJR8 Secrets of Aging: Dr. Raghav Sehgal Reveals Breakthroughs in Epigenetic Clocks and Systems Age https://i.ytimg.com/vi/5VW27IfWJR8/hqdefault.jpg Sign Up Today: https://peakhuman.ca/lead-generation-lp Join Dr. Sanjeev Goel in an interview with Dr. Raghav Sehgal, a PhD student at Yale and expert in epigenetic clocks. Discover how Dr. Sehgal's research sheds light on aging, from predicting chronological age to understanding the pace of aging and mortality risk. Learn about the concept of "systems age" and how different organs age at varying rates, impacting disease prevalence. Explore the potential for personalized treatments based on these findings. Dr. Sehgal also discusses the impact of lifestyle factors like diet and exercise on reversing epigenetic aging, offering practical insights for a healthier, more youthful life. Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs ******************** Link to Study https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2812392 📚 Purchase the Peak Longevity Prediction Pack 📚 → https://peakhuman.ca/product/peak-longevity-pack/ 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** About Raghav Sehgal: "I am a PhD student at Yale University and an expert in Computational Biomedical technologies with over a decade of experience embedding Data Science and Artificial Intelligence to the Biomedical space. My current research focus is on human aging and on the side I advice venture capital funds on which longevity and geroscience companies to invest in!" To learn more about Raghav please visit this site: https://www.raghav-sehgal.com/ ******************** TIMESTAMP: 00:00 - Introduction 01:05 - Background and Entry into Epigenetic Clocks 09:03 - History of Epigenetic Clocks 17:00 - Systems Age: Measuring Aging in 11 Organs https://www.youtube-nocookie.com/embed/5VW27IfWJR8 2445 2024-03-29T16:00:06.000Z 2026-10-22T18:32:06.745Z https://longevityharbor.com/de/watch/5VW27IfWJR8 Secrets of Aging: Dr. Raghav Sehgal Reveals Breakthroughs in Epigenetic Clocks and Systems Age https://i.ytimg.com/vi/5VW27IfWJR8/hqdefault.jpg Sign Up Today: https://peakhuman.ca/lead-generation-lp Join Dr. Sanjeev Goel in an interview with Dr. Raghav Sehgal, a PhD student at Yale and expert in epigenetic clocks. Discover how Dr. Sehgal's research sheds light on aging, from predicting chronological age to understanding the pace of aging and mortality risk. Learn about the concept of "systems age" and how different organs age at varying rates, impacting disease prevalence. Explore the potential for personalized treatments based on these findings. Dr. Sehgal also discusses the impact of lifestyle factors like diet and exercise on reversing epigenetic aging, offering practical insights for a healthier, more youthful life. Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs ******************** Link to Study https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2812392 📚 Purchase the Peak Longevity Prediction Pack 📚 → https://peakhuman.ca/product/peak-longevity-pack/ 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** About Raghav Sehgal: "I am a PhD student at Yale University and an expert in Computational Biomedical technologies with over a decade of experience embedding Data Science and Artificial Intelligence to the Biomedical space. My current research focus is on human aging and on the side I advice venture capital funds on which longevity and geroscience companies to invest in!" To learn more about Raghav please visit this site: https://www.raghav-sehgal.com/ ******************** TIMESTAMP: 00:00 - Introduction 01:05 - Background and Entry into Epigenetic Clocks 09:03 - History of Epigenetic Clocks 17:00 - Systems Age: Measuring Aging in 11 Organs https://www.youtube-nocookie.com/embed/5VW27IfWJR8 2445 2024-03-29T16:00:06.000Z 2026-10-22T18:32:06.745Z https://longevityharbor.com/en/watch/5WSWY611oJA Gesunde Ernährung und gute Gewohnheiten für ein langes Leben | Dr. Julia Fischer | ARD Gesund https://i.ytimg.com/vi/5WSWY611oJA/hqdefault.jpg Wir zeigen dir, wie du dein Leben um mehr als 20 Jahre verlängern kannst! Nein, das ist kein Clickbait. Dr. Julia Fischer stellt euch die Ergebnisse aus einer aktuellen US-Studie vor, die zu dem Schluss kommt: Mit 8 einfachen Gewohnheiten kannst du fit und gesund bis ins hohe Alter bleiben und die Lebenserwartung steigern. Welche das sind und ein paar Bonustipps gibt es im Video. 00:00 - Fit und gesund bleiben 01:00 - Länger leben mit 8 Tipps 02:00 - Gewohnheit Nr. 1 04:10 - Gewohnheit Nr. 2 06:50 - Tipp für den Darm 07:40 - Gewohnheit Nr. 3 09:20 - Gewohnheit Nr. 4 10:10 - Gewohnheit Nr. 5 10:50 - Gewohnheit Nr. 6 12:00 - Gewohnheit Nr. 7 12:55 - Gewohnheit Nr. 8 13:30 - Es ist nicht nur Verzicht Du willst mit dem Rauchen aufhören? Die Bundeszentrale für gesundheitliche Aufklärung steht dir mit Tipps und Ratschlägen zur Seite - hier kannst du die Mitarbeitenden kontaktieren: https://www.bzga.de/service/infotelefone/rauchentwoehnung/ Unsere Quellen: https://journals.physiology.org/doi/full/10.1152/japplphysiol.00080.2007 https://www.bzfe.de/ernaehrung-im-fokus/aus-der-aktuellen-ausgabe/die-darm-hirn-achse/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620288/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589951/ https://www.uni-kiel.de/de/detailansicht/news/040-mikrobiom-alzheimer https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1860-3282 https://www.ndr.de/ratgeber/gesundheit/Probiotika-und-Praebiotika-Darmflora-aufbauen,darmgesundheit100.html https://www.zdf.de/nachrichten/panorama/studie-lebenserwartung-lebensstil-100.html https://www.bib.bund.de/DE/Presse/Mitteilungen/2023/2023-05-10-Lebenserwartung-Deutschland-in-Westeuropa-unter-den-Schlusslichtern.html https://www.sciencedirect.com/science/article/abs/pii/S0091743523001639?via%3Dihub https://www.swr.de/wissen/lebensstilstudie-acht-faktoren-fuer-laengeres-leben-100.html https://nutrition2023.eventscribe.net/index.asp?presTarget=2435709 https://www.aerzteblatt.de/archiv/225771/Psychische-Erkrankungen-Die-innere-Uhr-tickt-nic https://www.youtube-nocookie.com/embed/5WSWY611oJA 900 2024-08-08T14:00:06.000Z 2026-10-22T18:43:10.886Z https://longevityharbor.com/de/watch/5WSWY611oJA Gesunde Ernährung und gute Gewohnheiten für ein langes Leben | Dr. Julia Fischer | ARD Gesund https://i.ytimg.com/vi/5WSWY611oJA/hqdefault.jpg Wir zeigen dir, wie du dein Leben um mehr als 20 Jahre verlängern kannst! Nein, das ist kein Clickbait. Dr. Julia Fischer stellt euch die Ergebnisse aus einer aktuellen US-Studie vor, die zu dem Schluss kommt: Mit 8 einfachen Gewohnheiten kannst du fit und gesund bis ins hohe Alter bleiben und die Lebenserwartung steigern. Welche das sind und ein paar Bonustipps gibt es im Video. 00:00 - Fit und gesund bleiben 01:00 - Länger leben mit 8 Tipps 02:00 - Gewohnheit Nr. 1 04:10 - Gewohnheit Nr. 2 06:50 - Tipp für den Darm 07:40 - Gewohnheit Nr. 3 09:20 - Gewohnheit Nr. 4 10:10 - Gewohnheit Nr. 5 10:50 - Gewohnheit Nr. 6 12:00 - Gewohnheit Nr. 7 12:55 - Gewohnheit Nr. 8 13:30 - Es ist nicht nur Verzicht Du willst mit dem Rauchen aufhören? Die Bundeszentrale für gesundheitliche Aufklärung steht dir mit Tipps und Ratschlägen zur Seite - hier kannst du die Mitarbeitenden kontaktieren: https://www.bzga.de/service/infotelefone/rauchentwoehnung/ Unsere Quellen: https://journals.physiology.org/doi/full/10.1152/japplphysiol.00080.2007 https://www.bzfe.de/ernaehrung-im-fokus/aus-der-aktuellen-ausgabe/die-darm-hirn-achse/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620288/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589951/ https://www.uni-kiel.de/de/detailansicht/news/040-mikrobiom-alzheimer https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1860-3282 https://www.ndr.de/ratgeber/gesundheit/Probiotika-und-Praebiotika-Darmflora-aufbauen,darmgesundheit100.html https://www.zdf.de/nachrichten/panorama/studie-lebenserwartung-lebensstil-100.html https://www.bib.bund.de/DE/Presse/Mitteilungen/2023/2023-05-10-Lebenserwartung-Deutschland-in-Westeuropa-unter-den-Schlusslichtern.html https://www.sciencedirect.com/science/article/abs/pii/S0091743523001639?via%3Dihub https://www.swr.de/wissen/lebensstilstudie-acht-faktoren-fuer-laengeres-leben-100.html https://nutrition2023.eventscribe.net/index.asp?presTarget=2435709 https://www.aerzteblatt.de/archiv/225771/Psychische-Erkrankungen-Die-innere-Uhr-tickt-nic https://www.youtube-nocookie.com/embed/5WSWY611oJA 900 2024-08-08T14:00:06.000Z 2026-10-22T18:43:10.886Z https://longevityharbor.com/en/watch/5_rX1Z1TWPo Von Ernährung bis Genetik – was wirklich zählt für gesundes Altern mit Dr. Andrea Gartenbach #56 https://i.ytimg.com/vi/5_rX1Z1TWPo/hqdefault.jpg Was unterscheidet personalisierte Medizin von klassischer Schulmedizin? Welche Longevity-Tools sind wirklich sinnvoll – und welche Tests und Supplemente eher Hype als Hilfe? Und auf welche Blutwerte kommt es wirklich an, wenn du langfristig gesund bleiben willst? In der neuen Folge des CYBS Podcasts spricht Thiemo Osterhaus mit Ärztin und Longevity-Expertin Dr. Andrea Gartenbach über die Chancen und Grenzen der personalisierten Medizin – und warum „Longevity“ oft mehr verspricht, als es hält. Gemeinsam klären sie: – Was personalisierte Prävention wirklich ausmacht – Welche Biomarker und genetischen Marker aus ärztlicher Sicht sinnvoll sind – Welche Supplemente mehr schaden als nutzen – Warum Diagnostik ohne klare Konsequenz oft nur für Verunsicherung sorgt – Und weshalb Schlaf, Ernährung und Bewegung immer noch die besten Longevity-Tools sind Andrea teilt ihre Erfahrungen aus der Praxis – und erklärt, warum echte Prävention vor allem eines braucht: weniger Dogmatik, mehr Kontext – und einen alltagstauglichen Plan. Andrea bei Instagram: https://www.instagram.com/dr.andreagartenbach/ The Art of Longevity Webseite: https://www.art-of-longevity.com/ Andrea's Webseite: https://www.gartenbach.com Thiemo bei Instagram: https://www.instagram.com/doc.thiemoosterhaus/ Thiemo bei Youtube:https://www.youtube.com/channel/UCdGXfp2yqhoLRKG3g_aMxvQ Thiemos persönlicher Newsletter: https://thiemoosterhaus.com/ Thiemos Buch – Der Blutwerte Code: https://www.amazon.de/Blutwerte-Code-Gesundheit-verraten-optimierst-SPIEGEL-Bestseller/dp/3742324004/ref=sr_1_1?adgrpid=70803171723&hvadid=392750590524&hvdev=c&hvlocphy=9042418&hvnetw=g&hvqmt=e&hvrand=2048149929730305015&hvtargid=kwd-1884631836165&hydadcr=22143_1973871&keywords=der+blutwerte+code&qid=1682682967&sr=8-1 Medletics Academy – Health Coach Ausbildung: https://www.medletics-academy.de/health-coach-ausbildung?utm_source=ytto&utm_medium=social&utm_campaign=pc2207 Medletics Academy – IDN Ausbildung: https://www.medletics-academy.de/idn?utm_source=ytto&utm_medium=social&utm_cam https://www.youtube-nocookie.com/embed/5_rX1Z1TWPo 4796 2025-07-22T16:30:03.000Z 2026-10-22T18:43:10.781Z https://longevityharbor.com/de/watch/5_rX1Z1TWPo Von Ernährung bis Genetik – was wirklich zählt für gesundes Altern mit Dr. Andrea Gartenbach #56 https://i.ytimg.com/vi/5_rX1Z1TWPo/hqdefault.jpg Was unterscheidet personalisierte Medizin von klassischer Schulmedizin? Welche Longevity-Tools sind wirklich sinnvoll – und welche Tests und Supplemente eher Hype als Hilfe? Und auf welche Blutwerte kommt es wirklich an, wenn du langfristig gesund bleiben willst? In der neuen Folge des CYBS Podcasts spricht Thiemo Osterhaus mit Ärztin und Longevity-Expertin Dr. Andrea Gartenbach über die Chancen und Grenzen der personalisierten Medizin – und warum „Longevity“ oft mehr verspricht, als es hält. Gemeinsam klären sie: – Was personalisierte Prävention wirklich ausmacht – Welche Biomarker und genetischen Marker aus ärztlicher Sicht sinnvoll sind – Welche Supplemente mehr schaden als nutzen – Warum Diagnostik ohne klare Konsequenz oft nur für Verunsicherung sorgt – Und weshalb Schlaf, Ernährung und Bewegung immer noch die besten Longevity-Tools sind Andrea teilt ihre Erfahrungen aus der Praxis – und erklärt, warum echte Prävention vor allem eines braucht: weniger Dogmatik, mehr Kontext – und einen alltagstauglichen Plan. Andrea bei Instagram: https://www.instagram.com/dr.andreagartenbach/ The Art of Longevity Webseite: https://www.art-of-longevity.com/ Andrea's Webseite: https://www.gartenbach.com Thiemo bei Instagram: https://www.instagram.com/doc.thiemoosterhaus/ Thiemo bei Youtube:https://www.youtube.com/channel/UCdGXfp2yqhoLRKG3g_aMxvQ Thiemos persönlicher Newsletter: https://thiemoosterhaus.com/ Thiemos Buch – Der Blutwerte Code: https://www.amazon.de/Blutwerte-Code-Gesundheit-verraten-optimierst-SPIEGEL-Bestseller/dp/3742324004/ref=sr_1_1?adgrpid=70803171723&hvadid=392750590524&hvdev=c&hvlocphy=9042418&hvnetw=g&hvqmt=e&hvrand=2048149929730305015&hvtargid=kwd-1884631836165&hydadcr=22143_1973871&keywords=der+blutwerte+code&qid=1682682967&sr=8-1 Medletics Academy – Health Coach Ausbildung: https://www.medletics-academy.de/health-coach-ausbildung?utm_source=ytto&utm_medium=social&utm_campaign=pc2207 Medletics Academy – IDN Ausbildung: https://www.medletics-academy.de/idn?utm_source=ytto&utm_medium=social&utm_cam https://www.youtube-nocookie.com/embed/5_rX1Z1TWPo 4796 2025-07-22T16:30:03.000Z 2026-10-22T18:43:10.781Z https://longevityharbor.com/en/watch/5d4cUnT1GSA Video description: food-based caloric restriction mimetics and a personal aging-rate story https://i.ytimg.com/vi/5d4cUnT1GSA/hqdefault.jpg The creator says she once lowered her biological pace of aging to 0.65, later saw 0.76 after a supplement mistake, and now documents a one-year food-based attempt; the description says results come in Episode 26. https://www.youtube-nocookie.com/embed/5d4cUnT1GSA 3004 2026-07-22T17:58:20.000Z 2026-10-22T23:27:42.991Z https://longevityharbor.com/de/watch/5d4cUnT1GSA Videobeschreibung: kalorienrestriktionsähnliche Lebensmittel und eine persönliche Alternsraten-Gesch https://i.ytimg.com/vi/5d4cUnT1GSA/hqdefault.jpg Die Erstellerin sagt, sie habe ihr biologisches Alterungstempo einst auf 0,65 gesenkt, nach einem Supplement-Fehler 0,76 gesehen und dokumentiere nun einen einjährigen Versuch über Lebensmittel; laut Beschreibung kommen Ergebnisse in Episode 26. https://www.youtube-nocookie.com/embed/5d4cUnT1GSA 3004 2026-07-22T17:58:20.000Z 2026-10-22T23:27:42.991Z https://longevityharbor.com/en/watch/5gd_4nCoBlg Video description: hidden inflammation after 40 and a proposed physician reset https://i.ytimg.com/vi/5gd_4nCoBlg/hqdefault.jpg The description says chronic inflammation can go unnoticed and may contribute to metabolic problems such as fatigue, belly fat and muscle issues in adults over 40; it promotes a free guide and a proposed five-lever reset. https://www.youtube-nocookie.com/embed/5gd_4nCoBlg 743 2026-08-29T01:45:31.000Z 2026-10-22T22:39:50.919Z https://longevityharbor.com/de/watch/5gd_4nCoBlg Videobeschreibung: verborgene Entzündung nach 40 und ein vorgeschlagener ärztlicher Reset https://i.ytimg.com/vi/5gd_4nCoBlg/hqdefault.jpg Laut Beschreibung kann chronische Entzündung unbemerkt bleiben und bei Erwachsenen über 40 zu Stoffwechselproblemen wie Müdigkeit, Bauchfett und Muskelproblemen beitragen; beworben wird ein kostenloser Leitfaden und ein vorgeschlagener Reset mit fünf Hebeln. https://www.youtube-nocookie.com/embed/5gd_4nCoBlg 743 2026-08-29T01:45:31.000Z 2026-10-22T22:39:50.919Z https://longevityharbor.com/en/watch/5jXCuQlb104 Video description: five exercises proposed for people over 70 https://i.ytimg.com/vi/5jXCuQlb104/hqdefault.jpg The description presents five exercises for people over 70, said to be based on clinical research and to support strength, balance, mobility, heart health and independence. It names no study, sample or measured result. https://www.youtube-nocookie.com/embed/5jXCuQlb104 1237 2026-08-23T14:34:05.000Z 2026-10-22T22:48:33.590Z https://longevityharbor.com/de/watch/5jXCuQlb104 Videobeschreibung: fünf Übungen als Vorschlag für Menschen über 70 https://i.ytimg.com/vi/5jXCuQlb104/hqdefault.jpg Die Beschreibung stellt fünf Übungen für Menschen über 70 vor, angeblich auf klinischer Forschung beruhend und förderlich für Kraft, Gleichgewicht, Mobilität, Herzgesundheit und Selbstständigkeit. Sie nennt keine Studie, Stichprobe oder gemessenes Ergebnis. https://www.youtube-nocookie.com/embed/5jXCuQlb104 1237 2026-08-23T14:34:05.000Z 2026-10-22T22:48:33.590Z https://longevityharbor.com/en/watch/5l8X-g0hWYY Exploring Aging and Aging Interventions with Aubrey de Grey https://i.ytimg.com/vi/5l8X-g0hWYY/hqdefault.jpg In this episode of the Longevity Optimization Podcast, Dr. DeGray discusses groundbreaking research in aging and longevity, focusing on combination therapies, the hallmarks of aging, and the potential of stem cell and gene therapies. He emphasizes the importance of rejuvenation over merely slowing aging and explores the role of the immune system in health. The conversation also touches on biological age testing, lifestyle factors, and the future of gene therapy in enhancing longevity. Aubrey de Grey is a British biomedical gerontologist and the founder of the SENS Research Foundation. He is a leading advocate for regenerative medicine, focusing on reversing the effects of aging by repairing cellular damage. Known for his bold vision of life extension, de Grey believes that with advanced therapies, humans could significantly extend their lifespan. He is the co-author of Ending Aging, and his work continues to shape the future of longevity science. Takeaways Combination therapies are crucial for understanding aging. Rejuvenation may be easier than slowing down aging. Stem cell therapies hold great promise for the future. The immune system plays a significant role in aging. Biological age testing can provide insights into health. Gene therapy is a promising avenue for longevity research. Lifestyle factors have limited impact on lifespan extension. Understanding the hallmarks of aging is essential for interventions. Preventative maintenance is key to longevity. The future of aging research is bright with new technologies. Chapters 00:00 Introduction to Longevity and Aging Research 02:50 Combination Therapies in Aging Research 05:57 The Hallmarks of Aging 09:12 Interventions for Rejuvenation 11:57 Stem Cell Therapies and Their Future 15:03 The Role of the Immune System in Aging 17:56 Insights on Aging and Rejuvenation 20:47 Biological Age Testing and Its Implications 24:01 The Future of Gene Therapy in Aging 26:49 Lifestyle Factors and Aging 30:04 Conclusion and Final Thoughts https://www.youtube-nocookie.com/embed/5l8X-g0hWYY 2058 2024-10-10T18:03:32.000Z 2026-10-22T19:32:33.548Z https://longevityharbor.com/de/watch/5l8X-g0hWYY Exploring Aging and Aging Interventions with Aubrey de Grey https://i.ytimg.com/vi/5l8X-g0hWYY/hqdefault.jpg In this episode of the Longevity Optimization Podcast, Dr. DeGray discusses groundbreaking research in aging and longevity, focusing on combination therapies, the hallmarks of aging, and the potential of stem cell and gene therapies. He emphasizes the importance of rejuvenation over merely slowing aging and explores the role of the immune system in health. The conversation also touches on biological age testing, lifestyle factors, and the future of gene therapy in enhancing longevity. Aubrey de Grey is a British biomedical gerontologist and the founder of the SENS Research Foundation. He is a leading advocate for regenerative medicine, focusing on reversing the effects of aging by repairing cellular damage. Known for his bold vision of life extension, de Grey believes that with advanced therapies, humans could significantly extend their lifespan. He is the co-author of Ending Aging, and his work continues to shape the future of longevity science. Takeaways Combination therapies are crucial for understanding aging. Rejuvenation may be easier than slowing down aging. Stem cell therapies hold great promise for the future. The immune system plays a significant role in aging. Biological age testing can provide insights into health. Gene therapy is a promising avenue for longevity research. Lifestyle factors have limited impact on lifespan extension. Understanding the hallmarks of aging is essential for interventions. Preventative maintenance is key to longevity. The future of aging research is bright with new technologies. Chapters 00:00 Introduction to Longevity and Aging Research 02:50 Combination Therapies in Aging Research 05:57 The Hallmarks of Aging 09:12 Interventions for Rejuvenation 11:57 Stem Cell Therapies and Their Future 15:03 The Role of the Immune System in Aging 17:56 Insights on Aging and Rejuvenation 20:47 Biological Age Testing and Its Implications 24:01 The Future of Gene Therapy in Aging 26:49 Lifestyle Factors and Aging 30:04 Conclusion and Final Thoughts https://www.youtube-nocookie.com/embed/5l8X-g0hWYY 2058 2024-10-10T18:03:32.000Z 2026-10-22T19:32:33.548Z https://longevityharbor.com/en/watch/5lEBuCGvkjc After 70, Your Muscles Are Wasting Away — THIS #1 Protein Reverses It (Eggs Can't Come Close) https://i.ytimg.com/vi/5lEBuCGvkjc/hqdefault.jpg Muscle loss after 70 is real, and eggs alone may not cover what aging muscle needs. This video looks at six less common protein foods and supplements often promoted for older adults, and what the research actually shows. You'll see why aging muscle responds more slowly to protein, how much protein research suggests, and which of these six options have real trial evidence behind them. What you'll learn: － What anabolic resistance is and why it matters for muscle after 60 and 70 － How much protein per day and per meal research suggests for older adults － What the evidence says about nutritional yeast, hemp seeds, and spirulina － Where collagen and bone broth fit, and what the trials really measured － Why sardines and omega-3 fats have some of the strongest trial support － How bovine colostrum compares with whey protein in the one trial we found Eggs, fish, dairy, beans, and strength training still do most of the work. The six items here are about filling gaps wisely, not replacing the basics. 👍 If this helped you, give it a like. 🔔 Subscribe to the channel for more science-based healthy aging tips. Share this video with someone you care about who wants to stay strong. Sources & references: － PROT-AGE Study Group / Evidence-based recommendations for optimal dietary protein intake in older people / Journal of the American Medical Directors Association / 2013 － Aragon, Tipton & Schoenfeld / Age-related muscle anabolic resistance: inevitable or preventable? / Nutrition Reviews / 2023 － Zdzieblik et al. / Collagen peptide supplementation with resistance training in elderly sarcopenic men / British Journal of Nutrition / 2015 － Smith et al. / Fish oil-derived n-3 PUFA therapy increases muscle mass and function in healthy older adults / American Journal of Clinical Nutrition / 2015 － Duff et al. / The effect of bovine colostrum supplementation in older adults during resistance training / International Journal of Sport Nutrition and Exercise Metabolism / 2014 ⚠️ Educational note This video is for gener https://www.youtube-nocookie.com/embed/5lEBuCGvkjc 1221 2026-10-20T12:00:21.000Z 2026-10-22T19:04:44.824Z https://longevityharbor.com/de/watch/5lEBuCGvkjc After 70, Your Muscles Are Wasting Away — THIS #1 Protein Reverses It (Eggs Can't Come Close) https://i.ytimg.com/vi/5lEBuCGvkjc/hqdefault.jpg Muscle loss after 70 is real, and eggs alone may not cover what aging muscle needs. This video looks at six less common protein foods and supplements often promoted for older adults, and what the research actually shows. You'll see why aging muscle responds more slowly to protein, how much protein research suggests, and which of these six options have real trial evidence behind them. What you'll learn: － What anabolic resistance is and why it matters for muscle after 60 and 70 － How much protein per day and per meal research suggests for older adults － What the evidence says about nutritional yeast, hemp seeds, and spirulina － Where collagen and bone broth fit, and what the trials really measured － Why sardines and omega-3 fats have some of the strongest trial support － How bovine colostrum compares with whey protein in the one trial we found Eggs, fish, dairy, beans, and strength training still do most of the work. The six items here are about filling gaps wisely, not replacing the basics. 👍 If this helped you, give it a like. 🔔 Subscribe to the channel for more science-based healthy aging tips. Share this video with someone you care about who wants to stay strong. Sources & references: － PROT-AGE Study Group / Evidence-based recommendations for optimal dietary protein intake in older people / Journal of the American Medical Directors Association / 2013 － Aragon, Tipton & Schoenfeld / Age-related muscle anabolic resistance: inevitable or preventable? / Nutrition Reviews / 2023 － Zdzieblik et al. / Collagen peptide supplementation with resistance training in elderly sarcopenic men / British Journal of Nutrition / 2015 － Smith et al. / Fish oil-derived n-3 PUFA therapy increases muscle mass and function in healthy older adults / American Journal of Clinical Nutrition / 2015 － Duff et al. / The effect of bovine colostrum supplementation in older adults during resistance training / International Journal of Sport Nutrition and Exercise Metabolism / 2014 ⚠️ Educational note This video is for gener https://www.youtube-nocookie.com/embed/5lEBuCGvkjc 1221 2026-10-20T12:00:21.000Z 2026-10-22T19:04:44.824Z https://longevityharbor.com/en/watch/5my153yqXJ8 Daily multivitamin and biological aging markers in healthy older adults: COSMOS trial description https://i.ytimg.com/vi/5my153yqXJ8/hqdefault.jpg A video description reports that in the large COSMOS randomized trial, a standard daily multivitamin taken for two years modestly slowed certain epigenetic aging clocks by about four months of biological aging compared with placebo in healthy adults averaging age 70; cocoa extract showed no such effect. https://www.youtube-nocookie.com/embed/5my153yqXJ8 460 2026-10-18T16:43:56.000Z 2026-10-22T19:52:00.042Z https://longevityharbor.com/de/watch/5my153yqXJ8 Tägliches Multivitamin und biologische Alterungsmarker bei gesunden älteren Erwachsenen: COSMOS-Stud https://i.ytimg.com/vi/5my153yqXJ8/hqdefault.jpg Eine Videobeschreibung berichtet, dass in der großen randomisierten COSMOS-Studie ein Standard-Multivitamin über zwei Jahre bestimmte epigenetische Alterungsuhren bei gesunden Erwachsenen mit Durchschnittsalter 70 im Vergleich zu Placebo bescheiden um etwa vier Monate biologischen Alterns verlangsamte; Kakaoextrakt zeigte diesen Effekt nicht. https://www.youtube-nocookie.com/embed/5my153yqXJ8 460 2026-10-18T16:43:56.000Z 2026-10-22T19:52:00.042Z https://longevityharbor.com/en/watch/5nDJ6xuWc0Y Brian Kennedy on Rapamycin Master Series | Aging is the biggest risk factor for age-related diseases https://i.ytimg.com/vi/5nDJ6xuWc0Y/hqdefault.jpg Professor Brian Kennedy from the National University of Singapore is one of the world's leading researchers in the longevity field and has done longevity research for more than two decades. He is active in many different longevity companies and has been the President and CEO at Buck Institute for Research on Aging. Throughout the years he has made many different important and revolutionary longevity discoveries. Currently he is also one of the persons who is trying to move the longevity forward in a much efficient and faster way. This work he is doing in Singapore where he is leading a huge longevity research project. This unique project is something we are going to talk about in the podcast. We will also talk about his research on Rapamycin and other interesting longevity topics. 00:00 Intro 02:13 Longevity interest and research 04:07 Lifespan discovery of sir2 in yeast 06:42 Lifespan discovery of TOR (mTOR) in yeast 07:14 mTOR and calorie restriction 09:19 mTOR and mechanistic downstream effects 09:55 mTOR activation and inhibition 10:20 Problem with mTOR chronic overactivation 12:41 Challenges in Singapore and in the world 13:19 Increase healthspan by slowing aging 14:37 Create a pipeline for healthy longevity 16:54 Potential in squaring the longevity curve 18:48 Validation of longevity interventions 21:00 Different biological clock 23:52 Connect the longevity pieces together 25:00 Hallmarks of aging 26:11 Seven pillars of aging are connected 27:58 Aging the biggest risk factor for age-related diseases 30:51 Combining longevity interventions 33:14 Risk of too much mTOR inhibition 36:14 Alpha-ketoglutarate (AKG) 39:38 Who benefits best in taking AKG 40:55 Brian's longevity stack 42:12 His experiences with Rapamycin 45:58 Cycling mTOR inhibition 48:20 Things to keep an eye on when taking Rapamycin 49:24 Start of a Rapamycin longevity trial 51:49 Rapalogs - Next generation mTOR inhibitors 53:02 Other ways to inhibit mTOR 54:44 Low vs high protein intake for longevity 57:26 Personalized longevity interventions 1: https://www.youtube-nocookie.com/embed/5nDJ6xuWc0Y 4264 2023-10-16T22:15:00.000Z 2026-10-22T17:43:41.762Z https://longevityharbor.com/de/watch/5nDJ6xuWc0Y Brian Kennedy on Rapamycin Master Series | Aging is the biggest risk factor for age-related diseases https://i.ytimg.com/vi/5nDJ6xuWc0Y/hqdefault.jpg Professor Brian Kennedy from the National University of Singapore is one of the world's leading researchers in the longevity field and has done longevity research for more than two decades. He is active in many different longevity companies and has been the President and CEO at Buck Institute for Research on Aging. Throughout the years he has made many different important and revolutionary longevity discoveries. Currently he is also one of the persons who is trying to move the longevity forward in a much efficient and faster way. This work he is doing in Singapore where he is leading a huge longevity research project. This unique project is something we are going to talk about in the podcast. We will also talk about his research on Rapamycin and other interesting longevity topics. 00:00 Intro 02:13 Longevity interest and research 04:07 Lifespan discovery of sir2 in yeast 06:42 Lifespan discovery of TOR (mTOR) in yeast 07:14 mTOR and calorie restriction 09:19 mTOR and mechanistic downstream effects 09:55 mTOR activation and inhibition 10:20 Problem with mTOR chronic overactivation 12:41 Challenges in Singapore and in the world 13:19 Increase healthspan by slowing aging 14:37 Create a pipeline for healthy longevity 16:54 Potential in squaring the longevity curve 18:48 Validation of longevity interventions 21:00 Different biological clock 23:52 Connect the longevity pieces together 25:00 Hallmarks of aging 26:11 Seven pillars of aging are connected 27:58 Aging the biggest risk factor for age-related diseases 30:51 Combining longevity interventions 33:14 Risk of too much mTOR inhibition 36:14 Alpha-ketoglutarate (AKG) 39:38 Who benefits best in taking AKG 40:55 Brian's longevity stack 42:12 His experiences with Rapamycin 45:58 Cycling mTOR inhibition 48:20 Things to keep an eye on when taking Rapamycin 49:24 Start of a Rapamycin longevity trial 51:49 Rapalogs - Next generation mTOR inhibitors 53:02 Other ways to inhibit mTOR 54:44 Low vs high protein intake for longevity 57:26 Personalized longevity interventions 1: https://www.youtube-nocookie.com/embed/5nDJ6xuWc0Y 4264 2023-10-16T22:15:00.000Z 2026-10-22T17:43:41.762Z https://longevityharbor.com/en/watch/5qh7jRjyiEs Wie bleibt man länger gesund? 3 Dinge aus der Longevity-Forschung (AVEA Webinar) https://i.ytimg.com/vi/5qh7jRjyiEs/hqdefault.jpg Wie bleibt man länger gesund? In diesem Webinar erklärt Nikolas Thing, Longevity Coach und Ernährungsexperte bei AVEA, drei Dinge, die du selbst beeinflussen kannst: den Blutzucker nach dem Essen, die Qualität deines Schlafs und den NAD+-Spiegel deiner Zellen. Ausgangspunkt ist der Unterschied zwischen chronologischem und biologischem Alter und die Kennzeichen des Alterns, von genomischer Instabilität und Telomeren bis zu Mitochondrien, Autophagie und Darmflora. Nach Schätzungen aus der Forschung wird der Alterungsprozess zu einem großen Teil vom Lebensstil bestimmt, nicht von den Genen. Was dieses Video behandelt: • Biologisches vs. chronologisches Alter, mit einem Beispiel aus der AVEA Community • Die Kennzeichen des Alterns, kurz erklärt • Tipp 1: Blutzuckerspitzen vermeiden (Tellerregel, Reihenfolge beim Essen) • Tipp 2: Schlaf optimieren mit der 3-2-1-Regel • Tipp 3: NAD+ verstehen: wofür die Zelle es braucht und welche Wege es gibt, den Spiegel zu unterstützen (NMN, Vitamin B3, Recycling) • Welche AVEA Produkte an welcher Stelle ansetzen Kapitel 0:00 Worum es geht und wer spricht 3:54 Biologisches vs. chronologisches Alter 5:48 Wie viel der Lebensstil ausmacht 7:00 Die Kennzeichen des Alterns 11:03 Die fünf Longevity-Säulen 12:48 Tipp 1: Blutzucker und Ernährung 16:42 Tipp 2: Schlaf und die 3-2-1-Regel 18:22 Tipp 3: NAD+ erklärt 23:08 Erfahrungen aus der Community 27:39 Das Longevity Bundle Was ist das AVEA Vitality Bundle? Die Kombination aus zwei AVEA Produkten: NMN (Longevir, 99 % Reinheit, 250 mg oder 500 mg Forte) und dem NAD+ Booster, entwickelt in der Schweiz mit Longevity-Forschenden. Was macht das Vitality Bundle? Es wurde entwickelt, um den NAD+-Spiegel der Zellen zu unterstützen, der mit dem Alter sinkt. Niacin (Vitamin B3) im Booster trägt zu einem normalen Energiestoffwechsel und zur Verringerung von Müdigkeit bei. Wie funktioniert das Vitality Bundle? NMN ist eine direkte Vorstufe von NAD+, die der Körper in NAD+ umwandeln kann. Der NAD+ Booster ergänzt sechs Inhaltsstoffe, die in der For https://www.youtube-nocookie.com/embed/5qh7jRjyiEs 1936 2026-09-10T09:08:00.000Z 2026-10-22T20:43:37.210Z https://longevityharbor.com/de/watch/5qh7jRjyiEs Wie bleibt man länger gesund? 3 Dinge aus der Longevity-Forschung (AVEA Webinar) https://i.ytimg.com/vi/5qh7jRjyiEs/hqdefault.jpg Wie bleibt man länger gesund? In diesem Webinar erklärt Nikolas Thing, Longevity Coach und Ernährungsexperte bei AVEA, drei Dinge, die du selbst beeinflussen kannst: den Blutzucker nach dem Essen, die Qualität deines Schlafs und den NAD+-Spiegel deiner Zellen. Ausgangspunkt ist der Unterschied zwischen chronologischem und biologischem Alter und die Kennzeichen des Alterns, von genomischer Instabilität und Telomeren bis zu Mitochondrien, Autophagie und Darmflora. Nach Schätzungen aus der Forschung wird der Alterungsprozess zu einem großen Teil vom Lebensstil bestimmt, nicht von den Genen. Was dieses Video behandelt: • Biologisches vs. chronologisches Alter, mit einem Beispiel aus der AVEA Community • Die Kennzeichen des Alterns, kurz erklärt • Tipp 1: Blutzuckerspitzen vermeiden (Tellerregel, Reihenfolge beim Essen) • Tipp 2: Schlaf optimieren mit der 3-2-1-Regel • Tipp 3: NAD+ verstehen: wofür die Zelle es braucht und welche Wege es gibt, den Spiegel zu unterstützen (NMN, Vitamin B3, Recycling) • Welche AVEA Produkte an welcher Stelle ansetzen Kapitel 0:00 Worum es geht und wer spricht 3:54 Biologisches vs. chronologisches Alter 5:48 Wie viel der Lebensstil ausmacht 7:00 Die Kennzeichen des Alterns 11:03 Die fünf Longevity-Säulen 12:48 Tipp 1: Blutzucker und Ernährung 16:42 Tipp 2: Schlaf und die 3-2-1-Regel 18:22 Tipp 3: NAD+ erklärt 23:08 Erfahrungen aus der Community 27:39 Das Longevity Bundle Was ist das AVEA Vitality Bundle? Die Kombination aus zwei AVEA Produkten: NMN (Longevir, 99 % Reinheit, 250 mg oder 500 mg Forte) und dem NAD+ Booster, entwickelt in der Schweiz mit Longevity-Forschenden. Was macht das Vitality Bundle? Es wurde entwickelt, um den NAD+-Spiegel der Zellen zu unterstützen, der mit dem Alter sinkt. Niacin (Vitamin B3) im Booster trägt zu einem normalen Energiestoffwechsel und zur Verringerung von Müdigkeit bei. Wie funktioniert das Vitality Bundle? NMN ist eine direkte Vorstufe von NAD+, die der Körper in NAD+ umwandeln kann. Der NAD+ Booster ergänzt sechs Inhaltsstoffe, die in der For https://www.youtube-nocookie.com/embed/5qh7jRjyiEs 1936 2026-09-10T09:08:00.000Z 2026-10-22T20:43:37.210Z https://longevityharbor.com/en/watch/5r13mM_pAIQ Podcast description: epigenetics, lifestyle and biological age with Dr. Manuel Burzler https://i.ytimg.com/vi/5r13mM_pAIQ/hqdefault.jpg The description announces a discussion with Dr. Manuel Burzler on how diet, sleep, stress, the gut microbiome and daily habits relate to gene regulation and biological aging, and where limits of longevity approaches lie. https://www.youtube-nocookie.com/embed/5r13mM_pAIQ 4911 2026-06-18T05:30:11.000Z 2026-10-22T23:57:08.728Z https://longevityharbor.com/de/watch/5r13mM_pAIQ Podcast-Beschreibung: Epigenetik, Lebensstil und biologisches Alter mit Dr. Manuel Burzler https://i.ytimg.com/vi/5r13mM_pAIQ/hqdefault.jpg Die Beschreibung kündigt ein Gespräch mit Dr. Manuel Burzler darüber an, wie Ernährung, Schlaf, Stress, Darmmikrobiom und tägliche Gewohnheiten mit Genregulation und biologischem Altern zusammenhängen und wo Grenzen von Longevity-Ansätzen liegen. https://www.youtube-nocookie.com/embed/5r13mM_pAIQ 4911 2026-06-18T05:30:11.000Z 2026-10-22T23:57:08.728Z https://longevityharbor.com/en/watch/5tRNTXwDAHg Scientists Found the Anti-Aging Mechanism Inside Rapamycin https://i.ytimg.com/vi/5tRNTXwDAHg/hqdefault.jpg Is aging finally optional? In this deep dive, we analyze the groundbreaking 2026 research on Rapamycin (Sirolimus) and the cellular "mTOR" mechanism that scientists just decoded. We explore the brand-new "Pulse Protocol" — a specific dosing strategy from the 2026 Ageless Trials that triggers autophagy and clears out senescent (zombie) cells without the traditional side effects. In this video, you will discover: ✅ The exact mechanism behind the 2026 Rapamycin breakthrough. ✅ How the "Pulse Protocol" reverses biological age by up to 3 years. ✅ The critical difference between mTORC1 and mTORC2 for longevity. ✅ Why biohackers are shifting from daily supplements to intermittent pulsing. Chapters: 0:00 - The 2026 Anti-Aging Discovery 1:30 - How Rapamycin Targets the mTOR Switch 3:45 - The Pulse Protocol: 2026 Dosage Data 5:20 - Reversing the DNA Methylation Clock 7:10 - Risks, Side Effects, and Future Outlook Disclaimer: This video is for educational and entertainment purposes only. It is not medical advice. Always consult with a healthcare professional before starting any longevity protocol. #Biohacking #Longevity #Rapamycin #AntiAging #HealthTech #2026Research #Sirolimus #Biology https://www.youtube-nocookie.com/embed/5tRNTXwDAHg 397 2026-03-24T17:00:13.000Z 2026-10-22T19:04:40.920Z https://longevityharbor.com/de/watch/5tRNTXwDAHg Scientists Found the Anti-Aging Mechanism Inside Rapamycin https://i.ytimg.com/vi/5tRNTXwDAHg/hqdefault.jpg Is aging finally optional? In this deep dive, we analyze the groundbreaking 2026 research on Rapamycin (Sirolimus) and the cellular "mTOR" mechanism that scientists just decoded. We explore the brand-new "Pulse Protocol" — a specific dosing strategy from the 2026 Ageless Trials that triggers autophagy and clears out senescent (zombie) cells without the traditional side effects. In this video, you will discover: ✅ The exact mechanism behind the 2026 Rapamycin breakthrough. ✅ How the "Pulse Protocol" reverses biological age by up to 3 years. ✅ The critical difference between mTORC1 and mTORC2 for longevity. ✅ Why biohackers are shifting from daily supplements to intermittent pulsing. Chapters: 0:00 - The 2026 Anti-Aging Discovery 1:30 - How Rapamycin Targets the mTOR Switch 3:45 - The Pulse Protocol: 2026 Dosage Data 5:20 - Reversing the DNA Methylation Clock 7:10 - Risks, Side Effects, and Future Outlook Disclaimer: This video is for educational and entertainment purposes only. It is not medical advice. Always consult with a healthcare professional before starting any longevity protocol. #Biohacking #Longevity #Rapamycin #AntiAging #HealthTech #2026Research #Sirolimus #Biology https://www.youtube-nocookie.com/embed/5tRNTXwDAHg 397 2026-03-24T17:00:13.000Z 2026-10-22T19:04:40.920Z https://longevityharbor.com/en/watch/5xlSa817mbY Morgan Levine | Aging Clocks https://i.ytimg.com/vi/5xlSa817mbY/hqdefault.jpg At Ending Age-Related Diseases 2019, Morgan Levine of the Yale School of Medicine offered an informative and in-depth talk about epigenetic clocks and other biomarkers, such as co-methylation networks and markers of senescent cells. ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a Lifespan Hero: http://lifespan.io/hero #Aging #Science #Clock https://www.youtube-nocookie.com/embed/5xlSa817mbY 1010 2019-09-11T13:58:41.000Z 2026-10-22T17:43:35.330Z https://longevityharbor.com/de/watch/5xlSa817mbY Morgan Levine | Aging Clocks https://i.ytimg.com/vi/5xlSa817mbY/hqdefault.jpg At Ending Age-Related Diseases 2019, Morgan Levine of the Yale School of Medicine offered an informative and in-depth talk about epigenetic clocks and other biomarkers, such as co-methylation networks and markers of senescent cells. ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a Lifespan Hero: http://lifespan.io/hero #Aging #Science #Clock https://www.youtube-nocookie.com/embed/5xlSa817mbY 1010 2019-09-11T13:58:41.000Z 2026-10-22T17:43:35.330Z https://longevityharbor.com/en/watch/5yBSM4bmYMo Video description on entropy, telomeres and cellular aging https://i.ytimg.com/vi/5yBSM4bmYMo/hqdefault.jpg The description says the video explores why bodies cannot repair themselves forever, covering DNA tips, cellular waste, the Hayflick Limit, telomere shortening and thermodynamics, and asks whether aging is a mistake or a feature of life. https://www.youtube-nocookie.com/embed/5yBSM4bmYMo 177 2026-05-19T12:00:07.000Z 2026-10-23T00:38:24.441Z https://longevityharbor.com/de/watch/5yBSM4bmYMo Videobeschreibung zu Entropie, Telomeren und zellulärem Altern https://i.ytimg.com/vi/5yBSM4bmYMo/hqdefault.jpg Laut Beschreibung untersucht das Video, warum sich der Körper nicht ewig reparieren kann: DNA-Endstücke, zellulärer Abfall, das Hayflick-Limit, Telomerverkürzung und Thermodynamik – und ob Altern ein Fehler oder ein Merkmal des Lebens ist. https://www.youtube-nocookie.com/embed/5yBSM4bmYMo 177 2026-05-19T12:00:07.000Z 2026-10-23T00:38:24.441Z https://longevityharbor.com/en/watch/6-fnJ0FSIw8 Video description claims epigenetic clocks, zombie cells and three lifestyle levers https://i.ytimg.com/vi/6-fnJ0FSIw8/hqdefault.jpg According to the description, the video explains the epigenetic clock, senescent 'zombie' cells and Yamanaka factors, and presents a 14–16 hour meal gap, fasted exercise and deep sleep as three levers to slow biological age. https://www.youtube-nocookie.com/embed/6-fnJ0FSIw8 618 2026-04-02T23:50:26.000Z 2026-10-23T01:49:12.306Z https://longevityharbor.com/de/watch/6-fnJ0FSIw8 Videobeschreibung nennt epigenetische Uhren, Zombiezellen und drei Lebensstil-Hebel https://i.ytimg.com/vi/6-fnJ0FSIw8/hqdefault.jpg Laut Beschreibung erklärt das Video die epigenetische Uhr, seneszente „Zombiezellen“ und Yamanaka-Faktoren und nennt eine Essenspause von 14–16 Stunden, Fasten-Training und Tiefschlaf als drei Hebel, um das biologische Alter zu verlangsamen. https://www.youtube-nocookie.com/embed/6-fnJ0FSIw8 618 2026-04-02T23:50:26.000Z 2026-10-23T01:49:12.306Z https://longevityharbor.com/en/watch/60XNKvtwNt0 Wunder der Selbstheilung! Best Ager Oster Auferstehung #longevity #lifespan #ostern #heilung #natur https://i.ytimg.com/vi/60XNKvtwNt0/hqdefault.jpg Epigenetik und gesund Altern ist die Welt von Longevity - die Gesundheit im Alter zu verlängern! Mit dem 90 Tage Epigenetik Transformation Begleitprogramm zeige ich in einer 360 Grad Betrachtung, welche Bereiche deiner Umwelt du beeinflussen kannst, um deine Gesundheit ganzheitlich zu verbessern. Buche dir ein 30 min Klarheitsgespräch kostenfrei mit Lydia: https://calendly.com/lydiafillbach/erstgespraech_epigenetik_transformation_30min Gerne kannst du meine Angebote hier kennen lernen: Epigenetik 90 Tage Transformation 1:1 Begleitprogramm mit Lydia https://www.lebenswert-wien.at/traumkoerper/ Gesundheitszentrum in Wien & Webshop: https://www.lebenswert-wien.at/ Human Design Mentoring 1:1 mit Lydia: https://www.lebenswert-wien.at/human-design-analyse/ Ich bin mir sicher, dass du bei mir nicht nur KLARHEIT findest, sondern auch den nächsten wichtigen IMPULS auf dem Weg zu deinem entspannt erfülltem Leben als strahlend selbstbewusstes Menschenkind :-) Deine Lydia Fillbach https://www.youtube-nocookie.com/embed/60XNKvtwNt0 98 2025-04-21T17:30:50.000Z 2026-10-22T19:21:26.499Z https://longevityharbor.com/de/watch/60XNKvtwNt0 Wunder der Selbstheilung! Best Ager Oster Auferstehung #longevity #lifespan #ostern #heilung #natur https://i.ytimg.com/vi/60XNKvtwNt0/hqdefault.jpg Epigenetik und gesund Altern ist die Welt von Longevity - die Gesundheit im Alter zu verlängern! Mit dem 90 Tage Epigenetik Transformation Begleitprogramm zeige ich in einer 360 Grad Betrachtung, welche Bereiche deiner Umwelt du beeinflussen kannst, um deine Gesundheit ganzheitlich zu verbessern. Buche dir ein 30 min Klarheitsgespräch kostenfrei mit Lydia: https://calendly.com/lydiafillbach/erstgespraech_epigenetik_transformation_30min Gerne kannst du meine Angebote hier kennen lernen: Epigenetik 90 Tage Transformation 1:1 Begleitprogramm mit Lydia https://www.lebenswert-wien.at/traumkoerper/ Gesundheitszentrum in Wien & Webshop: https://www.lebenswert-wien.at/ Human Design Mentoring 1:1 mit Lydia: https://www.lebenswert-wien.at/human-design-analyse/ Ich bin mir sicher, dass du bei mir nicht nur KLARHEIT findest, sondern auch den nächsten wichtigen IMPULS auf dem Weg zu deinem entspannt erfülltem Leben als strahlend selbstbewusstes Menschenkind :-) Deine Lydia Fillbach https://www.youtube-nocookie.com/embed/60XNKvtwNt0 98 2025-04-21T17:30:50.000Z 2026-10-22T19:21:26.499Z https://longevityharbor.com/en/watch/61RMJCQPaqo Video description links 12 hallmarks of ageing to symptoms in women over 40 https://i.ytimg.com/vi/61RMJCQPaqo/hqdefault.jpg According to the description, Leslie Kenny walks through the full framework of the 12 hallmarks of ageing, and Dr. Stephanie connects each hallmark to symptoms that the Betties know firsthand, such as brain fog, midlife weight gain and fatigue. https://www.youtube-nocookie.com/embed/61RMJCQPaqo 259 2026-04-15T06:00:11.000Z 2026-10-23T01:35:10.164Z https://longevityharbor.com/de/watch/61RMJCQPaqo Videobeschreibung verknüpft 12 Hallmarks des Alterns mit Symptomen bei Frauen über 40 https://i.ytimg.com/vi/61RMJCQPaqo/hqdefault.jpg Laut Beschreibung geht Leslie Kenny das vollständige Rahmenwerk der 12 Hallmarks des Alterns durch, und Dr. Stephanie verknüpft jedes Hallmark mit Symptomen, die die Betties aus eigener Erfahrung kennen, etwa Brain Fog, Gewichtszunahme in der Lebensmitte und Erschöpfung. https://www.youtube-nocookie.com/embed/61RMJCQPaqo 259 2026-04-15T06:00:11.000Z 2026-10-23T01:35:10.164Z https://longevityharbor.com/en/watch/625HM-cYKyk Video description: natural aging versus aging with muscle after 60 https://i.ytimg.com/vi/625HM-cYKyk/hqdefault.jpg The description contrasts natural aging with proactively keeping strength and lean mass past 60 and says muscle loss, falls, metabolism and independence are covered; it gives no study data. https://www.youtube-nocookie.com/embed/625HM-cYKyk 697 2026-10-05T23:00:19.000Z 2026-10-22T21:18:22.365Z https://longevityharbor.com/de/watch/625HM-cYKyk Videobeschreibung: natürliches Altern versus Altern mit Muskeln nach 60 https://i.ytimg.com/vi/625HM-cYKyk/hqdefault.jpg Die Beschreibung stellt natürliches Altern dem aktiven Erhalt von Kraft und fettfreier Masse nach 60 gegenüber und nennt Muskelschwund, Stürze, Stoffwechsel und Selbstständigkeit als Themen; Studiendaten fehlen. https://www.youtube-nocookie.com/embed/625HM-cYKyk 697 2026-10-05T23:00:19.000Z 2026-10-22T21:18:22.365Z https://longevityharbor.com/en/watch/66UFiOsR4Go Rapamycin, microbiome, genetic engineering... Which would be the best antiaging intervention? EP.2 https://i.ytimg.com/vi/66UFiOsR4Go/hqdefault.jpg Welcome to our latest video featuring insightful interviews conducted at the 4th Timepie Longevity Forum. In this engaging segment, we sit down with distinguished scholars to discuss the most promising anti-aging interventions anticipated in the coming decade. From microbiome interventions to senolytics, epigenetic interventions, rapamycin, and beyond, our experts delve into the forefront of research and development in the field of longevity. Join us as we explore the potential breakthroughs that hold promise for extending human lifespan and enhancing quality of life. For more stuff on anti-aging and longevity Twitter: https://twitter.com/TimePieChina Linkedin: https://www.linkedin.com/company/timepie/ -------------------------------------------------------------------------------------------------------- TimePie is a science popularization platform based on Fudan University alumni, with over 600,000 subscribers in China. Our mission is to help people live longer and age healthier. This channel is where you can find fresh information from the anti-aging industry and exclusive lectures delivered by famous scholars and biohackers. Stay tuned for more updates from TimePie. #longevity #aging #antiaging #lifespan #intervention #gut https://www.youtube-nocookie.com/embed/66UFiOsR4Go 255 2024-02-15T10:00:04.000Z 2026-10-22T19:04:40.783Z https://longevityharbor.com/de/watch/66UFiOsR4Go Rapamycin, microbiome, genetic engineering... Which would be the best antiaging intervention? EP.2 https://i.ytimg.com/vi/66UFiOsR4Go/hqdefault.jpg Welcome to our latest video featuring insightful interviews conducted at the 4th Timepie Longevity Forum. In this engaging segment, we sit down with distinguished scholars to discuss the most promising anti-aging interventions anticipated in the coming decade. From microbiome interventions to senolytics, epigenetic interventions, rapamycin, and beyond, our experts delve into the forefront of research and development in the field of longevity. Join us as we explore the potential breakthroughs that hold promise for extending human lifespan and enhancing quality of life. For more stuff on anti-aging and longevity Twitter: https://twitter.com/TimePieChina Linkedin: https://www.linkedin.com/company/timepie/ -------------------------------------------------------------------------------------------------------- TimePie is a science popularization platform based on Fudan University alumni, with over 600,000 subscribers in China. Our mission is to help people live longer and age healthier. This channel is where you can find fresh information from the anti-aging industry and exclusive lectures delivered by famous scholars and biohackers. Stay tuned for more updates from TimePie. #longevity #aging #antiaging #lifespan #intervention #gut https://www.youtube-nocookie.com/embed/66UFiOsR4Go 255 2024-02-15T10:00:04.000Z 2026-10-22T19:04:40.783Z https://longevityharbor.com/en/watch/6AjKOe-yZeM Rapamycin's SURPRISING Effects on Aged IMMUNE SYSTEMS | 18 - RF #4 https://i.ytimg.com/vi/6AjKOe-yZeM/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan The R-Files episode 1: https://www.youtube.com/watch?v=czx_-DqnnrQ&t=1675s The R-Files episode 2: https://www.youtube.com/watch?v=EgIy0ghrDmo&t=140s The R-Files episode 3: https://www.youtube.com/watch?v=jLV5nOenD-g&feature=youtu.be The R-Files is a series of episodes about rapamycin, a naturally occurring compound originally discovered in soil samples from Easter Island, also known as Rapa Nui (hence the drug's name). Rapamycin belongs to a class of drugs called macrolides and has potent immunosuppressive and anti-proliferative effects. The drug has garnered attention for its potential anti-aging properties and has attracted research interest for its ability to extend lifespan and delay age-related diseases in various model organisms, including yeast and mice. In the fourth episode of the R-Files, Matt discusses research demonstrating that rapamycin rejuvenates the aged mouse immune system to respond to a flu vaccine as if it were in a youthful state. He also discusses papers suggesting that rapamycin may have similar effects on human immune systems. 0:00 Trailer 0:41 Introduction 1:25 A big year for rapamycin: Rapamycin fed late in life extends lifespan in genetically heterogeneous mice 2:38 mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells 8:50 The immune challenge experiment 18:20 Unanswered questions 19:20 The lifespan experiment 25:26 Caveats 26:46 Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice 27:48 Translation to humans 28:27 TORC1 inhibition enhances immune function and reduces infections in the elderly 34:52 mTOR inhibition improves immune function in the elderly 38:44 Takeaways Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relatio https://www.youtube-nocookie.com/embed/6AjKOe-yZeM 2422 2024-03-25T14:00:03.000Z 2026-10-22T19:04:40.910Z https://longevityharbor.com/de/watch/6AjKOe-yZeM Rapamycin's SURPRISING Effects on Aged IMMUNE SYSTEMS | 18 - RF #4 https://i.ytimg.com/vi/6AjKOe-yZeM/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan The R-Files episode 1: https://www.youtube.com/watch?v=czx_-DqnnrQ&t=1675s The R-Files episode 2: https://www.youtube.com/watch?v=EgIy0ghrDmo&t=140s The R-Files episode 3: https://www.youtube.com/watch?v=jLV5nOenD-g&feature=youtu.be The R-Files is a series of episodes about rapamycin, a naturally occurring compound originally discovered in soil samples from Easter Island, also known as Rapa Nui (hence the drug's name). Rapamycin belongs to a class of drugs called macrolides and has potent immunosuppressive and anti-proliferative effects. The drug has garnered attention for its potential anti-aging properties and has attracted research interest for its ability to extend lifespan and delay age-related diseases in various model organisms, including yeast and mice. In the fourth episode of the R-Files, Matt discusses research demonstrating that rapamycin rejuvenates the aged mouse immune system to respond to a flu vaccine as if it were in a youthful state. He also discusses papers suggesting that rapamycin may have similar effects on human immune systems. 0:00 Trailer 0:41 Introduction 1:25 A big year for rapamycin: Rapamycin fed late in life extends lifespan in genetically heterogeneous mice 2:38 mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells 8:50 The immune challenge experiment 18:20 Unanswered questions 19:20 The lifespan experiment 25:26 Caveats 26:46 Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice 27:48 Translation to humans 28:27 TORC1 inhibition enhances immune function and reduces infections in the elderly 34:52 mTOR inhibition improves immune function in the elderly 38:44 Takeaways Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relatio https://www.youtube-nocookie.com/embed/6AjKOe-yZeM 2422 2024-03-25T14:00:03.000Z 2026-10-22T19:04:40.910Z https://longevityharbor.com/en/watch/6N0d6s_MCbw NMN and NAD+: what the video description says about aging evidence https://i.ytimg.com/vi/6N0d6s_MCbw/hqdefault.jpg The description presents NMN as a molecule the body can use to support NAD+ levels, notes that animal research exists, and says human studies remain small and short-term. https://www.youtube-nocookie.com/embed/6N0d6s_MCbw 248 2026-09-14T14:23:19.000Z 2026-10-22T22:12:21.029Z https://longevityharbor.com/de/watch/6N0d6s_MCbw NMN und NAD+: Was die Videobeschreibung zur Alterungs-Evidenz sagt https://i.ytimg.com/vi/6N0d6s_MCbw/hqdefault.jpg Die Beschreibung stellt NMN als Molekül dar, das der Körper zur Unterstützung der NAD+-Spiegel nutzen kann, nennt Tierforschung und bezeichnet Humanstudien als noch klein und kurzfristig. https://www.youtube-nocookie.com/embed/6N0d6s_MCbw 248 2026-09-14T14:23:19.000Z 2026-10-22T22:12:21.029Z https://longevityharbor.com/en/watch/6Nt57rbwP5Y Video description: three exercises claimed to outperform walking alone https://i.ytimg.com/vi/6Nt57rbwP5Y/hqdefault.jpg The description claims three expert-recommended exercises target ankle stability, posture and pressure force, said to be more effective than walking alone; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/6Nt57rbwP5Y 605 2026-06-07T22:00:06.000Z 2026-10-23T00:06:34.493Z https://longevityharbor.com/de/watch/6Nt57rbwP5Y Videobeschreibung: drei Übungen, die besser als Gehen allein sein sollen https://i.ytimg.com/vi/6Nt57rbwP5Y/hqdefault.jpg Die Beschreibung behauptet, drei von Experten empfohlene Übungen zielten auf Knöchelstabilität, Haltung und Druckkraft und seien wirksamer als Gehen allein; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/6Nt57rbwP5Y 605 2026-06-07T22:00:06.000Z 2026-10-23T00:06:34.493Z https://longevityharbor.com/en/watch/6UrD8SgkVcc Video description: DO-HEALTH trial on vitamin D, omega-3, exercise and DNA methylation clocks https://i.ytimg.com/vi/6UrD8SgkVcc/hqdefault.jpg The description says the episode examines DO-HEALTH, a large clinical trial of vitamin D, omega-3 and exercise and their individual and additive effects on DNA methylation clocks of biological aging in older adults. https://www.youtube-nocookie.com/embed/6UrD8SgkVcc 2822 2026-06-26T13:21:48.000Z 2026-10-22T23:48:19.223Z https://longevityharbor.com/de/watch/6UrD8SgkVcc Videobeschreibung: DO-HEALTH-Studie zu Vitamin D, Omega-3, Bewegung und DNA-Methylierungsuhren https://i.ytimg.com/vi/6UrD8SgkVcc/hqdefault.jpg Laut Beschreibung untersucht die Episode DO-HEALTH, eine große klinische Studie zu Vitamin D, Omega-3 und Bewegung sowie deren einzelne und additive Effekte auf DNA-Methylierungsuhren des biologischen Alterns bei älteren Erwachsenen. https://www.youtube-nocookie.com/embed/6UrD8SgkVcc 2822 2026-06-26T13:21:48.000Z 2026-10-22T23:48:19.223Z https://longevityharbor.com/en/watch/6XQ-5Exe7Hc Video description on 12 hallmarks of aging and diet claims https://i.ytimg.com/vi/6XQ-5Exe7Hc/hqdefault.jpg The description says the video covers the 12 hallmarks of aging, epigenetics, methylation, metabolism and glucose processing, and states these depend heavily on what we eat and how we treat our body. It also advertises a continuing education course and offers practical information, but gives no results. https://www.youtube-nocookie.com/embed/6XQ-5Exe7Hc 868 2025-12-25T12:27:54.000Z 2026-10-23T03:10:07.705Z https://longevityharbor.com/de/watch/6XQ-5Exe7Hc Videobeschreibung zu 12 Hallmarks des Alterns und Ernährungsaussagen https://i.ytimg.com/vi/6XQ-5Exe7Hc/hqdefault.jpg Die Beschreibung sagt, das Video behandele die 12 Hallmarks des Alterns, Epigenetik, Methylierung, Stoffwechsel und Glukoseverarbeitung, und behauptet, diese hingen stark davon ab, was wir essen und wie wir unseren Körper behandeln. Sie bewirbt zudem einen Fortbildungskurs und verspricht praktische Informationen, nennt aber keine Ergebnisse. https://www.youtube-nocookie.com/embed/6XQ-5Exe7Hc 868 2025-12-25T12:27:54.000Z 2026-10-23T03:10:07.705Z https://longevityharbor.com/en/watch/6Zj3l-5lTVo Targeting Aging Ep3 - Rapamycin Benefits, Side Effects & Doses | Professor Matt Kaeberlein Interview https://i.ytimg.com/vi/6Zj3l-5lTVo/hqdefault.jpg Professor Kaeberlein talks about rapamycin, what are the benefits that it has shown, some of the side effects and myths around them and what doses he is using in the Dog Aging Project. Dr. Matt Kaeberlein is a Professor of Pathology, Adjunct Professor of Genome Sciences, and Adjunct Professor of Oral Health Sciences at the University of Washington. His research interests are focused on basic mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He is currently leading The Dog Aging project, a large multi-year trial to study the aging of companion dogs in a normal environment. He has published nearly 200 papers in top scientific journals and has been recognized by several prestigious awards, including a Breakthroughs in Gerontology Award, and most recent GSA’s 2020 Robert W. Kleemeier Award Professor Kaeberlein at University of Washington https://depts.washington.edu/mbwc/about/profile/matt-kaeberlein Dog Aging Project. https://dogagingproject.zendesk.com/hc/en-us #DogAgingProject #rapamycin #Healthspan https://www.youtube-nocookie.com/embed/6Zj3l-5lTVo 1136 2021-01-11T13:52:08.000Z 2026-10-22T17:43:41.775Z https://longevityharbor.com/de/watch/6Zj3l-5lTVo Targeting Aging Ep3 - Rapamycin Benefits, Side Effects & Doses | Professor Matt Kaeberlein Interview https://i.ytimg.com/vi/6Zj3l-5lTVo/hqdefault.jpg Professor Kaeberlein talks about rapamycin, what are the benefits that it has shown, some of the side effects and myths around them and what doses he is using in the Dog Aging Project. Dr. Matt Kaeberlein is a Professor of Pathology, Adjunct Professor of Genome Sciences, and Adjunct Professor of Oral Health Sciences at the University of Washington. His research interests are focused on basic mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He is currently leading The Dog Aging project, a large multi-year trial to study the aging of companion dogs in a normal environment. He has published nearly 200 papers in top scientific journals and has been recognized by several prestigious awards, including a Breakthroughs in Gerontology Award, and most recent GSA’s 2020 Robert W. Kleemeier Award Professor Kaeberlein at University of Washington https://depts.washington.edu/mbwc/about/profile/matt-kaeberlein Dog Aging Project. https://dogagingproject.zendesk.com/hc/en-us #DogAgingProject #rapamycin #Healthspan https://www.youtube-nocookie.com/embed/6Zj3l-5lTVo 1136 2021-01-11T13:52:08.000Z 2026-10-22T17:43:41.775Z https://longevityharbor.com/en/watch/6_x4nVOGjWQ Seneszenz & Auswirkungen auf unser Altern mit Prof.Dr. Brigitte König https://i.ytimg.com/vi/6_x4nVOGjWQ/hqdefault.jpg Epigenetik TV - Im Interview: Prof. Dr. Brigitte König über Seneszenz & ihre Auswirkungen auf unser Altern Prof. Dr. Brigitte König ist Expertin für Mikrobiologie und Infektionsimmunologie Sie hat Biologie, Chemie und Medizin studiert, sie hat habilitiert im Fach »Medizinische Mikrobiologie und Infektionsimmunologie« und hat 2008 das Labor MMD gegründet. Heute haben wir eine von Deutschlands größten Forscherinnen im Interview. Ich war ganz besonders gespannt, darauf, was uns Brigitte über Epigenetik, die Methylierung und über viele andere Prozesse berichtet, um auch mal die wissenschaftliche Seite zu durchleuchten. Was wissen wir über die Epigenetik und was ist mehr Vermutung oder Theorie. Sei gespannt, es war ein sehr interessantes und wissensreiches interview. ------------------------ Das Ganze Interview findest du auf https://epi-genes.com/Epigenetik_TV.aspx ------------------------ https://www.youtube-nocookie.com/embed/6_x4nVOGjWQ 98 2023-05-16T05:00:02.000Z 2026-10-23T02:24:27.206Z https://longevityharbor.com/de/watch/6_x4nVOGjWQ Seneszenz & Auswirkungen auf unser Altern mit Prof.Dr. Brigitte König https://i.ytimg.com/vi/6_x4nVOGjWQ/hqdefault.jpg Epigenetik TV - Im Interview: Prof. Dr. Brigitte König über Seneszenz & ihre Auswirkungen auf unser Altern Prof. Dr. Brigitte König ist Expertin für Mikrobiologie und Infektionsimmunologie Sie hat Biologie, Chemie und Medizin studiert, sie hat habilitiert im Fach »Medizinische Mikrobiologie und Infektionsimmunologie« und hat 2008 das Labor MMD gegründet. Heute haben wir eine von Deutschlands größten Forscherinnen im Interview. Ich war ganz besonders gespannt, darauf, was uns Brigitte über Epigenetik, die Methylierung und über viele andere Prozesse berichtet, um auch mal die wissenschaftliche Seite zu durchleuchten. Was wissen wir über die Epigenetik und was ist mehr Vermutung oder Theorie. Sei gespannt, es war ein sehr interessantes und wissensreiches interview. ------------------------ Das Ganze Interview findest du auf https://epi-genes.com/Epigenetik_TV.aspx ------------------------ https://www.youtube-nocookie.com/embed/6_x4nVOGjWQ 98 2023-05-16T05:00:02.000Z 2026-10-23T02:24:27.206Z https://longevityharbor.com/en/watch/6afIlbiKDew Why We Age - And What We Can Do About It | Brian Kennedy | Peter Attia Podcast https://i.ytimg.com/vi/6afIlbiKDew/hqdefault.jpg Want to support the channel? Become a member to get early access to our videos, watch member-only videos and request summaries of podcasts of your choice! https://www.youtube.com/channel/UClk1399isACmkiswDijHC6g/join In this podcast episode, Brian Kennedy explores the complex biology of aging, emphasizing the need for mathematical models grounded in physical principles to move beyond descriptive approaches. He critiques the "hallmarks of aging" framework, proposing that aging results from a decline in the body's homeostatic network and resilience. Chronic inflammation and dysregulation of the mTOR pathway are highlighted as central factors, with rapamycin discussed as a promising but limited geroprotective drug. Kennedy also reviews biological clocks, emerging interventions like alpha-ketoglutarate, and the challenges of translating animal research to humans. He stresses the importance of lifestyle factors, conventional medicine, and cautious combination of therapies. Finally, he addresses the potential and risks of advanced technologies such as gene therapy and AI in aging research, advocating for rigorous trials and careful integration of new tools. 00:00 Introduction 01:26 The Role of Inflammation and mTOR in Aging 02:56 Models of Aging and the “Slope” of Lifespan 04:06 Rapamycin: Potential and Limitations 05:15 Biological Clocks and Measuring Aging 06:30 Alpha-Ketoglutarate and Other Emerging Interventions 07:37 The Challenge of Translating Animal Research to Humans 08:39 The Role of Lifestyle and Conventional Medicine 09:44 The Complexity of Combining Interventions 10:39 The Promise and Perils of Emerging Technologies This video is a podcast summary of The Peter Attia Drive Podcast episode titled '357 ‒ A new era of longevity science: models of aging, rapamycin trials, biological clocks, & more'. Link: https://youtu.be/7yNvz_0Q1eQ Publish date: Jul 21, 2025 Summary article: https://podmarized.com/episodes/the-peter-attia-drive-podcast/357-a-new-era-of-longevity-science-models-of-aging-rapamycin-trials- https://www.youtube-nocookie.com/embed/6afIlbiKDew 692 2025-07-21T19:00:06.000Z 2026-10-22T19:32:33.148Z https://longevityharbor.com/de/watch/6afIlbiKDew Why We Age - And What We Can Do About It | Brian Kennedy | Peter Attia Podcast https://i.ytimg.com/vi/6afIlbiKDew/hqdefault.jpg Want to support the channel? Become a member to get early access to our videos, watch member-only videos and request summaries of podcasts of your choice! https://www.youtube.com/channel/UClk1399isACmkiswDijHC6g/join In this podcast episode, Brian Kennedy explores the complex biology of aging, emphasizing the need for mathematical models grounded in physical principles to move beyond descriptive approaches. He critiques the "hallmarks of aging" framework, proposing that aging results from a decline in the body's homeostatic network and resilience. Chronic inflammation and dysregulation of the mTOR pathway are highlighted as central factors, with rapamycin discussed as a promising but limited geroprotective drug. Kennedy also reviews biological clocks, emerging interventions like alpha-ketoglutarate, and the challenges of translating animal research to humans. He stresses the importance of lifestyle factors, conventional medicine, and cautious combination of therapies. Finally, he addresses the potential and risks of advanced technologies such as gene therapy and AI in aging research, advocating for rigorous trials and careful integration of new tools. 00:00 Introduction 01:26 The Role of Inflammation and mTOR in Aging 02:56 Models of Aging and the “Slope” of Lifespan 04:06 Rapamycin: Potential and Limitations 05:15 Biological Clocks and Measuring Aging 06:30 Alpha-Ketoglutarate and Other Emerging Interventions 07:37 The Challenge of Translating Animal Research to Humans 08:39 The Role of Lifestyle and Conventional Medicine 09:44 The Complexity of Combining Interventions 10:39 The Promise and Perils of Emerging Technologies This video is a podcast summary of The Peter Attia Drive Podcast episode titled '357 ‒ A new era of longevity science: models of aging, rapamycin trials, biological clocks, & more'. Link: https://youtu.be/7yNvz_0Q1eQ Publish date: Jul 21, 2025 Summary article: https://podmarized.com/episodes/the-peter-attia-drive-podcast/357-a-new-era-of-longevity-science-models-of-aging-rapamycin-trials- https://www.youtube-nocookie.com/embed/6afIlbiKDew 692 2025-07-21T19:00:06.000Z 2026-10-22T19:32:33.148Z https://longevityharbor.com/en/watch/6ah2CinwKhY Video description claims mitochondria control energy, performance and aging in men over 50 https://i.ytimg.com/vi/6ah2CinwKhY/hqdefault.jpg The description presents mitochondria as an overlooked system behind declining energy, performance, weight, mental sharpness and intimate function in men over 50, and lists scientific references; it reports no study results of its own. https://www.youtube-nocookie.com/embed/6ah2CinwKhY 1745 2026-01-04T20:20:34.000Z 2026-10-23T03:02:14.691Z https://longevityharbor.com/de/watch/6ah2CinwKhY Videobeschreibung behauptet, Mitochondrien steuern Energie, Leistung und Altern bei Männern über 50 https://i.ytimg.com/vi/6ah2CinwKhY/hqdefault.jpg Die Beschreibung stellt Mitochondrien als übersehenes System hinter nachlassender Energie, Leistung, Gewicht, geistiger Schärfe und intimer Funktion bei Männern über 50 dar und nennt wissenschaftliche Quellen; eigene Studienergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/6ah2CinwKhY 1745 2026-01-04T20:20:34.000Z 2026-10-23T03:02:14.691Z https://longevityharbor.com/en/watch/6b4ZCL5k3Ck Podcast description: Chris Mirabile on longevity science, healthspan and supplement evidence https://i.ytimg.com/vi/6b4ZCL5k3Ck/hqdefault.jpg In this podcast description, Chris Mirabile argues that extending human lifespan is not yet scientifically proven, while improving healthspan and reducing individual health risks may be more realistic today. He says lifestyle basics still outperform many expensive biohacking tools and that longevity products should be judged by evidence, not hype. https://www.youtube-nocookie.com/embed/6b4ZCL5k3Ck 6306 2026-10-15T14:13:10.000Z 2026-10-22T19:53:06.582Z https://longevityharbor.com/de/watch/6b4ZCL5k3Ck Podcast-Beschreibung: Chris Mirabile über Langlebigkeitsforschung, Healthspan und Belege für Nahrung https://i.ytimg.com/vi/6b4ZCL5k3Ck/hqdefault.jpg In dieser Podcast-Beschreibung argumentiert Chris Mirabile, dass eine Verlängerung der menschlichen Lebensspanne wissenschaftlich noch nicht belegt ist, während eine Verbesserung der Healthspan und die Senkung individueller Gesundheitsrisiken heute realistischer sein könnten. Seiner Darstellung nach übertreffen Lebensstil-Grundlagen viele teure Biohacking-Werkzeuge, und Langlebigkeitsprodukte sollten an Belegen statt an Werbung gemessen werden. https://www.youtube-nocookie.com/embed/6b4ZCL5k3Ck 6306 2026-10-15T14:13:10.000Z 2026-10-22T19:53:06.582Z https://longevityharbor.com/en/watch/6bSX2f3gqNg Video explains hallmarks of aging, senescent cells and epigenetic loss https://i.ytimg.com/vi/6bSX2f3gqNg/hqdefault.jpg The description says the video explains the 2013 and 2023 hallmarks of aging frameworks, senescent 'zombie' cells and epigenetic information loss, and calls the hallmarks a checklist rather than a complete theory. https://www.youtube-nocookie.com/embed/6bSX2f3gqNg 443 2026-10-01T20:00:17.000Z 2026-10-22T21:31:51.722Z https://longevityharbor.com/de/watch/6bSX2f3gqNg Video erklärt Hallmarks des Alterns, seneszente Zellen und epigenetischen Verlust https://i.ytimg.com/vi/6bSX2f3gqNg/hqdefault.jpg Laut Beschreibung erklärt das Video die Hallmark-Rahmenwerke von 2013 und 2023, seneszente „Zombie“-Zellen und epigenetischen Informationsverlust; die Hallmarks seien eine Checkliste, keine vollständige Theorie. https://www.youtube-nocookie.com/embed/6bSX2f3gqNg 443 2026-10-01T20:00:17.000Z 2026-10-22T21:31:51.722Z https://longevityharbor.com/en/watch/6kQcwIVmOlE A reality check on longevity: Mark Hamalainen’s plan to solve aging - Episode 7 https://i.ytimg.com/vi/6kQcwIVmOlE/hqdefault.jpg 🚀 Show notes for this episode available here: https://peterottsjo.beehiiv.com/p/levity-podcast-7-mark-hamalainen 🚀 Don't forget to SUBSCRIBE to our channel: https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA?sub_confirmation=1 🚀 Looking for LEVITY Merch? https://levity-7.creator-spring.com/ ------------------------ There are countless reasons to admire Mark Hamalainen, and one of them is his brutal honesty. While many longevity influencers confidently declare that longevity escape velocity and indefinite lifespans are just around the corner, you won’t get such easy assurances from Mark. That’s because, and this might seem counterintuitive at first, he’s one of the most deeply committed advocates for solving aging that I’ve encountered. Mark, a former director of science at Synthego and a former researcher at SENS Research Foundation (Aubrey de Grey has called him his protégé), has dedicated over two decades to tackling humanity’s greatest challenge. You see, Mark's honesty doesn't stem from pessimism, but from a deep commitment to reality-based thinking. His mission isn’t driven by hype but by a relentless pursuit of tangible progress in the fight against aging. I first met Mark at the Longevity Biotech Fellowship (LBF) retreat in Sweden in January 2024, where I had the opportunity to witness his vision and dedication firsthand. It left a lasting impression, not only on me but likely on everyone who attended. Here was someone who wasn’t just dreaming about a future where aging is solved - he was meticulously planning it, working hard to remove the roadblocks that stand in the way. His work with the LBF, the Longevity Acceleration Roadmap, and his broader efforts in the longevity community are all about taking concrete, actionable steps toward a future where the passing of time is not a death sentence - all the while knowing that this goal is one of the most complex challenges humanity has ever faced. In this episode, Mark discusses several key strategies that he believes are essential to makin https://www.youtube-nocookie.com/embed/6kQcwIVmOlE 6694 2024-09-03T03:00:03.000Z 2026-10-22T19:32:33.512Z https://longevityharbor.com/de/watch/6kQcwIVmOlE A reality check on longevity: Mark Hamalainen’s plan to solve aging - Episode 7 https://i.ytimg.com/vi/6kQcwIVmOlE/hqdefault.jpg 🚀 Show notes for this episode available here: https://peterottsjo.beehiiv.com/p/levity-podcast-7-mark-hamalainen 🚀 Don't forget to SUBSCRIBE to our channel: https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA?sub_confirmation=1 🚀 Looking for LEVITY Merch? https://levity-7.creator-spring.com/ ------------------------ There are countless reasons to admire Mark Hamalainen, and one of them is his brutal honesty. While many longevity influencers confidently declare that longevity escape velocity and indefinite lifespans are just around the corner, you won’t get such easy assurances from Mark. That’s because, and this might seem counterintuitive at first, he’s one of the most deeply committed advocates for solving aging that I’ve encountered. Mark, a former director of science at Synthego and a former researcher at SENS Research Foundation (Aubrey de Grey has called him his protégé), has dedicated over two decades to tackling humanity’s greatest challenge. You see, Mark's honesty doesn't stem from pessimism, but from a deep commitment to reality-based thinking. His mission isn’t driven by hype but by a relentless pursuit of tangible progress in the fight against aging. I first met Mark at the Longevity Biotech Fellowship (LBF) retreat in Sweden in January 2024, where I had the opportunity to witness his vision and dedication firsthand. It left a lasting impression, not only on me but likely on everyone who attended. Here was someone who wasn’t just dreaming about a future where aging is solved - he was meticulously planning it, working hard to remove the roadblocks that stand in the way. His work with the LBF, the Longevity Acceleration Roadmap, and his broader efforts in the longevity community are all about taking concrete, actionable steps toward a future where the passing of time is not a death sentence - all the while knowing that this goal is one of the most complex challenges humanity has ever faced. In this episode, Mark discusses several key strategies that he believes are essential to makin https://www.youtube-nocookie.com/embed/6kQcwIVmOlE 6694 2024-09-03T03:00:03.000Z 2026-10-22T19:32:33.512Z https://longevityharbor.com/en/watch/6sT4P7br75c Exploring Effects of Dasatinib, Quercetin, and Fisetin on DNA Methylation Clocks | Aging-US https://i.ytimg.com/vi/6sT4P7br75c/hqdefault.jpg Aging-US #published this #trending research #paper on February 22, 2024, in Volume 16, Issue 4, entitled, “Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions" by researchers from the Institute For Hormonal Balance, Orlando, FL; TruDiagnostic, Lexington, KY; Buck Institute for Research on Aging, Novato, CA; Cornell University, Ithaca, NY. @TruDiagnostic @buckinstituteforresearchon4229 @Cornell #aging #senolytics #epigenetics #dna #research #researchpaper #openaccess #openscience #peerreview #journal #publication #publishing #trending #meded DOI - https://doi.org/10.18632/aging.205581 Corresponding authors - Varun B. Dwaraka - varun@trudiagnostic.com Abstract Senolytics, small molecules targeting cellular senescence, have emerged as potential therapeutics to enhance health span. However, their impact on epigenetic age remains unstudied. This study aimed to assess the effects of Dasatinib and Quercetin (DQ) senolytic treatment on DNA methylation (DNAm), epigenetic age, and immune cell subsets. In a Phase I pilot study, 19 participants received DQ for 6 months, with DNAm measured at baseline, 3 months, and 6 months. Significant increases in epigenetic age acceleration were observed in first-generation epigenetic clocks and mitotic clocks at 3 and 6 months, along with a notable decrease in telomere length. However, no significant differences were observed in second and third-generation clocks. Building upon these findings, a subsequent investigation evaluated the combination of DQ with Fisetin (DQF), a well-known antioxidant and antiaging senolytic molecule. After one year, 19 participants (including 10 from the initial study) received DQF for 6 months, with DNAm assessed at baseline and 6 months. Remarkably, the addition of Fisetin to the treatment resulted in non-significant increases in epigenetic age acceleration, suggesting a potential mitigating effect of Fisetin on the impact of DQ on epigenetic aging. Furthermore, our anal https://www.youtube-nocookie.com/embed/6sT4P7br75c 139 2024-03-05T18:59:09.000Z 2026-10-22T19:21:23.257Z https://longevityharbor.com/de/watch/6sT4P7br75c Exploring Effects of Dasatinib, Quercetin, and Fisetin on DNA Methylation Clocks | Aging-US https://i.ytimg.com/vi/6sT4P7br75c/hqdefault.jpg Aging-US #published this #trending research #paper on February 22, 2024, in Volume 16, Issue 4, entitled, “Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions" by researchers from the Institute For Hormonal Balance, Orlando, FL; TruDiagnostic, Lexington, KY; Buck Institute for Research on Aging, Novato, CA; Cornell University, Ithaca, NY. @TruDiagnostic @buckinstituteforresearchon4229 @Cornell #aging #senolytics #epigenetics #dna #research #researchpaper #openaccess #openscience #peerreview #journal #publication #publishing #trending #meded DOI - https://doi.org/10.18632/aging.205581 Corresponding authors - Varun B. Dwaraka - varun@trudiagnostic.com Abstract Senolytics, small molecules targeting cellular senescence, have emerged as potential therapeutics to enhance health span. However, their impact on epigenetic age remains unstudied. This study aimed to assess the effects of Dasatinib and Quercetin (DQ) senolytic treatment on DNA methylation (DNAm), epigenetic age, and immune cell subsets. In a Phase I pilot study, 19 participants received DQ for 6 months, with DNAm measured at baseline, 3 months, and 6 months. Significant increases in epigenetic age acceleration were observed in first-generation epigenetic clocks and mitotic clocks at 3 and 6 months, along with a notable decrease in telomere length. However, no significant differences were observed in second and third-generation clocks. Building upon these findings, a subsequent investigation evaluated the combination of DQ with Fisetin (DQF), a well-known antioxidant and antiaging senolytic molecule. After one year, 19 participants (including 10 from the initial study) received DQF for 6 months, with DNAm assessed at baseline and 6 months. Remarkably, the addition of Fisetin to the treatment resulted in non-significant increases in epigenetic age acceleration, suggesting a potential mitigating effect of Fisetin on the impact of DQ on epigenetic aging. Furthermore, our anal https://www.youtube-nocookie.com/embed/6sT4P7br75c 139 2024-03-05T18:59:09.000Z 2026-10-22T19:21:23.257Z https://longevityharbor.com/en/watch/6slFNO4hWv8 NANO Talk discussion: how muscles may influence cancer, dementia and aging https://i.ytimg.com/vi/6slFNO4hWv8/hqdefault.jpg In this NANO Talk description, experts discuss myokines, muscle as a metabolic organ, and whether targeted muscle stimuli could slow cancer growth, neurodegenerative processes and aging effects such as sarcopenia. https://www.youtube-nocookie.com/embed/6slFNO4hWv8 3564 2026-09-30T15:00:16.000Z 2026-10-22T21:38:14.343Z https://longevityharbor.com/de/watch/6slFNO4hWv8 NANO-Talk-Gespräch: Wie Muskeln Krebs, Demenz und Alterung beeinflussen könnten https://i.ytimg.com/vi/6slFNO4hWv8/hqdefault.jpg In dieser NANO-Talk-Beschreibung diskutieren Fachleute über Myokine, Muskeln als Stoffwechselorgan und ob gezielte Muskelreize Krebswachstum, neurodegenerative Prozesse und Alterungseffekte wie Sarkopenie bremsen könnten. https://www.youtube-nocookie.com/embed/6slFNO4hWv8 3564 2026-09-30T15:00:16.000Z 2026-10-22T21:38:14.343Z https://longevityharbor.com/en/watch/6tb1SmbtN30 Podcast description: Leslie Kenny on spermidine, autophagy and healthy aging https://i.ytimg.com/vi/6tb1SmbtN30/hqdefault.jpg In this podcast description, Leslie Kenny links spermidine to autophagy, the body's cellular cleanup, and discusses lifestyle habits for healthspan; the video itself was not reviewed. https://www.youtube-nocookie.com/embed/6tb1SmbtN30 4517 2026-09-14T07:00:34.000Z 2026-10-22T22:12:47.233Z https://longevityharbor.com/de/watch/6tb1SmbtN30 Podcast-Beschreibung: Leslie Kenny über Spermidin, Autophagie und gesundes Altern https://i.ytimg.com/vi/6tb1SmbtN30/hqdefault.jpg In dieser Podcast-Beschreibung verbindet Leslie Kenny Spermidin mit Autophagie, der zellulären Aufräumfunktion des Körpers, und spricht über Lebensstilgewohnheiten für die Gesundheitsspanne; das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/6tb1SmbtN30 4517 2026-09-14T07:00:34.000Z 2026-10-22T22:12:47.233Z https://longevityharbor.com/en/watch/7-NvskI8Ve0 Longevity & Aging Series (S3, E6): Girish Harinath | Aging-US https://i.ytimg.com/vi/7-NvskI8Ve0/hqdefault.jpg In this episode of the Longevity & Aging Series, Girish Harinath from AgelessRx joins host Dr. Evgeniy Galimov to discuss a #research paper he co-authored in Volume 17, Issue 4 of Aging-US, titled “Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results.” @agelessrx #author #interview #authorinterview #aging #rapamycin #geroscience #longevity #healthspan #openaccess #openscience #peerreviewed #journal #publishing #meded DOI - https://doi.org/10.18632/aging.206235 Corresponding author - Stefanie L. Morgan - stefanie@agelessrx.com Stefanie L. Morgan interview - https://www.youtube.com/watch?v=2qlIiVh2OJs Abstract video - https://www.youtube.com/watch?v=z5j2nyK2HZ8 Abstract Design: This 48-week decentralized, double-blinded, randomized, placebo-controlled trial (NCT04488601) evaluated the long-term safety of intermittent low-dose rapamycin in a healthy, normative-aging human cohort. Participants received placebo, 5 mg or 10 mg compounded rapamycin weekly. The primary outcome measure was visceral adiposity (by DXA scan), secondary outcomes were blood biomarkers, and lean tissue and bone mineral content (by DXA scan). Established surveys were utilized to evaluate health and well-being. Safety was assessed through adverse events and blood biomarker monitoring. Results: Adverse and serious adverse events were similar across all groups. Visceral adiposity did not change significantly (ηp2 = 0.001, p = 0.942), and changes in blood biomarkers remained within normal ranges. Lean tissue mass (ηp2 = 0.202, p = 0.013) and self-reported pain (ηp2 = 0.168, p = 0.015) improved significantly for women using 10 mg rapamycin. Self-reported emotional well-being (ηp2 = 0.108, p = 0.023) and general health (ηp2 = 0.166, p = 0.004) also improved for those using 5 mg rapamycin. No other significant effects were observed. Conclusions: Low-dose, intermittent rapamycin administration over 48 weeks is relatively safe in healthy, normative-aging adults, and was associated with significant improvem https://www.youtube-nocookie.com/embed/7-NvskI8Ve0 3678 2025-09-26T13:57:23.000Z 2026-10-22T19:32:34.487Z https://longevityharbor.com/de/watch/7-NvskI8Ve0 Longevity & Aging Series (S3, E6): Girish Harinath | Aging-US https://i.ytimg.com/vi/7-NvskI8Ve0/hqdefault.jpg In this episode of the Longevity & Aging Series, Girish Harinath from AgelessRx joins host Dr. Evgeniy Galimov to discuss a #research paper he co-authored in Volume 17, Issue 4 of Aging-US, titled “Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results.” @agelessrx #author #interview #authorinterview #aging #rapamycin #geroscience #longevity #healthspan #openaccess #openscience #peerreviewed #journal #publishing #meded DOI - https://doi.org/10.18632/aging.206235 Corresponding author - Stefanie L. Morgan - stefanie@agelessrx.com Stefanie L. Morgan interview - https://www.youtube.com/watch?v=2qlIiVh2OJs Abstract video - https://www.youtube.com/watch?v=z5j2nyK2HZ8 Abstract Design: This 48-week decentralized, double-blinded, randomized, placebo-controlled trial (NCT04488601) evaluated the long-term safety of intermittent low-dose rapamycin in a healthy, normative-aging human cohort. Participants received placebo, 5 mg or 10 mg compounded rapamycin weekly. The primary outcome measure was visceral adiposity (by DXA scan), secondary outcomes were blood biomarkers, and lean tissue and bone mineral content (by DXA scan). Established surveys were utilized to evaluate health and well-being. Safety was assessed through adverse events and blood biomarker monitoring. Results: Adverse and serious adverse events were similar across all groups. Visceral adiposity did not change significantly (ηp2 = 0.001, p = 0.942), and changes in blood biomarkers remained within normal ranges. Lean tissue mass (ηp2 = 0.202, p = 0.013) and self-reported pain (ηp2 = 0.168, p = 0.015) improved significantly for women using 10 mg rapamycin. Self-reported emotional well-being (ηp2 = 0.108, p = 0.023) and general health (ηp2 = 0.166, p = 0.004) also improved for those using 5 mg rapamycin. No other significant effects were observed. Conclusions: Low-dose, intermittent rapamycin administration over 48 weeks is relatively safe in healthy, normative-aging adults, and was associated with significant improvem https://www.youtube-nocookie.com/embed/7-NvskI8Ve0 3678 2025-09-26T13:57:23.000Z 2026-10-22T19:32:34.487Z https://longevityharbor.com/en/watch/75Gct1YWhX8 Video description: senescent cells, senolytics and aging research https://i.ytimg.com/vi/75Gct1YWhX8/hqdefault.jpg The description says the video explains how senescent cells accumulate with age and contribute to chronic inflammation, and how senolytics are being studied as a possible way to remove these cells and support healthier aging. https://www.youtube-nocookie.com/embed/75Gct1YWhX8 597 2026-07-13T16:30:38.000Z 2026-10-22T23:32:12.130Z https://longevityharbor.com/de/watch/75Gct1YWhX8 Videobeschreibung: seneszente Zellen, Senolytika und Alternsforschung https://i.ytimg.com/vi/75Gct1YWhX8/hqdefault.jpg Laut Beschreibung erklärt das Video, wie sich seneszente Zellen mit dem Alter ansammeln und zu chronischer Entzündung beitragen, und wie Senolytika als möglicher Weg untersucht werden, diese Zellen zu entfernen und gesünderes Altern zu unterstützen. https://www.youtube-nocookie.com/embed/75Gct1YWhX8 597 2026-07-13T16:30:38.000Z 2026-10-22T23:32:12.130Z https://longevityharbor.com/en/watch/76RdFh84X-w Unlock the Secrets of Fasting: Discover How Long You Should Fast for Autophagy! https://i.ytimg.com/vi/76RdFh84X-w/hqdefault.jpg Exploring the fascinating world of fasting reveals a complex relationship between time and metabolic benefits. The journey to autophagy is nuanced, with emerging evidence suggesting that reaching a fasted state for 12 to 16 hours may be key. Yet, while human studies are limited, the promising advantages such as improved glucose levels, better blood pressure regulation, and weight loss cannot be ignored. Discover the potential of intermittent fasting and its effects on metabolic health. Dive into the science and elevate your understanding of fasting today. #autophagy #intermittentfasting #healthylifestyle #metabolichealth #fastingtips #nutrition #wellness #shorts https://www.youtube-nocookie.com/embed/76RdFh84X-w 108 2025-08-13T09:30:48.000Z 2026-10-22T19:32:30.725Z https://longevityharbor.com/de/watch/76RdFh84X-w Unlock the Secrets of Fasting: Discover How Long You Should Fast for Autophagy! https://i.ytimg.com/vi/76RdFh84X-w/hqdefault.jpg Exploring the fascinating world of fasting reveals a complex relationship between time and metabolic benefits. The journey to autophagy is nuanced, with emerging evidence suggesting that reaching a fasted state for 12 to 16 hours may be key. Yet, while human studies are limited, the promising advantages such as improved glucose levels, better blood pressure regulation, and weight loss cannot be ignored. Discover the potential of intermittent fasting and its effects on metabolic health. Dive into the science and elevate your understanding of fasting today. #autophagy #intermittentfasting #healthylifestyle #metabolichealth #fastingtips #nutrition #wellness #shorts https://www.youtube-nocookie.com/embed/76RdFh84X-w 108 2025-08-13T09:30:48.000Z 2026-10-22T19:32:30.725Z https://longevityharbor.com/en/watch/77ZaDHf1GGU Video description: review of NAD⁺ supplements such as NMN and nicotinamide riboside https://i.ytimg.com/vi/77ZaDHf1GGU/hqdefault.jpg According to the description, a new research review examines what NAD supplements such as NMN and nicotinamide riboside actually do and what the evidence says about healthy aging, longevity and overall wellness. The description names a PRISMA-guided systematic review of preclinical and clinical evidence but reports no results. https://www.youtube-nocookie.com/embed/77ZaDHf1GGU 110 2026-02-10T19:46:24.000Z 2026-10-23T02:35:48.617Z https://longevityharbor.com/de/watch/77ZaDHf1GGU Videobeschreibung: Übersicht zu NAD⁺-Supplementen wie NMN und Nicotinamid-Ribosid https://i.ytimg.com/vi/77ZaDHf1GGU/hqdefault.jpg Laut Beschreibung untersucht eine neue Forschungsübersicht, was NAD-Supplemente wie NMN und Nicotinamid-Ribosid tatsächlich bewirken und was die Evidenz zu gesundem Altern, Langlebigkeit und allgemeinem Wohlbefinden sagt. Die Beschreibung nennt eine PRISMA-geleitete systematische Übersicht präklinischer und klinischer Evidenz, berichtet aber keine Ergebnisse. https://www.youtube-nocookie.com/embed/77ZaDHf1GGU 110 2026-02-10T19:46:24.000Z 2026-10-23T02:35:48.617Z https://longevityharbor.com/en/watch/79p1X_7rAMo Supplements for Longevity & Their Efficacy | Dr. Peter Attia https://i.ytimg.com/vi/79p1X_7rAMo/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive. We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan. Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk. Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan. Access the full show notes for this episode: https://www.hubermanlab.com/episode/dr-peter-attia-supplements-for-longevity-their-efficacy *Thank you to our sponsors* AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Dr. Peter Attia* Websi https://www.youtube-nocookie.com/embed/79p1X_7rAMo 9042 2024-07-29T12:00:12.000Z 2026-10-22T18:43:09.931Z https://longevityharbor.com/de/watch/79p1X_7rAMo Supplements for Longevity & Their Efficacy | Dr. Peter Attia https://i.ytimg.com/vi/79p1X_7rAMo/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive. We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan. Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk. Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan. Access the full show notes for this episode: https://www.hubermanlab.com/episode/dr-peter-attia-supplements-for-longevity-their-efficacy *Thank you to our sponsors* AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Dr. Peter Attia* Websi https://www.youtube-nocookie.com/embed/79p1X_7rAMo 9042 2024-07-29T12:00:12.000Z 2026-10-22T18:43:09.931Z https://longevityharbor.com/en/watch/79wlYsl6JnM S1E06 - Cellular Senescence & SASP https://i.ytimg.com/vi/79wlYsl6JnM/hqdefault.jpg Season 1: The Science of Aging | Episode 6: Cellular Senescence & SASP In this insightful episode, we delve into the fascinating world of cellular senescence, exploring its role as both a protector and adversary in the aging process. Through engaging discussions and expert insights, we unravel the biological paradox where senescent cells, initially beneficial as safeguards against cancer and critical for tissue repair, become detrimental as they accumulate with age, driving chronic inflammation and degeneration. We carry listeners through a detailed examination of the intricate mechanisms behind cellular senescence, focusing on pathways involving key proteins like P53 and P16-INK4A, and the complex cocktail of molecules known as the senescence-associated secretory phenotype (SASP). Highlighting landmark mouse studies, we provide compelling evidence of how targeted removal of these cells can delay aging and enhance healthspan, offering hope for potential therapeutic interventions in humans. Join us on a journey from the microscopic to the macroscopic, as we discuss groundbreaking research that not only reshapes our understanding of aging but also opens up the tantalizing possibility of redefining the very essence of human longevity and health. https://www.youtube-nocookie.com/embed/79wlYsl6JnM 3083 2025-08-13T19:13:30.000Z 2026-10-22T19:32:34.562Z https://longevityharbor.com/de/watch/79wlYsl6JnM S1E06 - Cellular Senescence & SASP https://i.ytimg.com/vi/79wlYsl6JnM/hqdefault.jpg Season 1: The Science of Aging | Episode 6: Cellular Senescence & SASP In this insightful episode, we delve into the fascinating world of cellular senescence, exploring its role as both a protector and adversary in the aging process. Through engaging discussions and expert insights, we unravel the biological paradox where senescent cells, initially beneficial as safeguards against cancer and critical for tissue repair, become detrimental as they accumulate with age, driving chronic inflammation and degeneration. We carry listeners through a detailed examination of the intricate mechanisms behind cellular senescence, focusing on pathways involving key proteins like P53 and P16-INK4A, and the complex cocktail of molecules known as the senescence-associated secretory phenotype (SASP). Highlighting landmark mouse studies, we provide compelling evidence of how targeted removal of these cells can delay aging and enhance healthspan, offering hope for potential therapeutic interventions in humans. Join us on a journey from the microscopic to the macroscopic, as we discuss groundbreaking research that not only reshapes our understanding of aging but also opens up the tantalizing possibility of redefining the very essence of human longevity and health. https://www.youtube-nocookie.com/embed/79wlYsl6JnM 3083 2025-08-13T19:13:30.000Z 2026-10-22T19:32:34.562Z https://longevityharbor.com/en/watch/7AGVrOK9Ms4 Video description: epigenome, organ age and biological age in aging https://i.ytimg.com/vi/7AGVrOK9Ms4/hqdefault.jpg The description says aging is not only about DNA mutations and suggests the epigenome may be the real culprit; it also mentions organ age versus biological age. https://www.youtube-nocookie.com/embed/7AGVrOK9Ms4 110 2026-09-28T04:01:30.000Z 2026-10-22T21:41:56.715Z https://longevityharbor.com/de/watch/7AGVrOK9Ms4 Videobeschreibung: Epigenom, Organalter und biologisches Alter beim Altern https://i.ytimg.com/vi/7AGVrOK9Ms4/hqdefault.jpg Die Beschreibung sagt, Altern beruhe nicht nur auf DNA-Mutationen, und nennt das Epigenom als möglichen eigentlichen Verursacher; außerdem erwähnt sie Organalter gegenüber biologischem Alter. https://www.youtube-nocookie.com/embed/7AGVrOK9Ms4 110 2026-09-28T04:01:30.000Z 2026-10-22T21:41:56.715Z https://longevityharbor.com/en/watch/7BYvkN3hZhc How Fast Are You Really Ageing? The Science Behind Epigenetic Clocks https://i.ytimg.com/vi/7BYvkN3hZhc/hqdefault.jpg In this episode of "The Science of Turning Back Time," host Charmaine Shepherd delves into the fascinating world of biological aging with Dr. Varun Dwaraka, head of bioinformatics at True Diagnostics. Discover how lifestyle changes, such as diet, exercise, and stress management, can significantly impact your biological age. Dr. Dwaraka shares insights on the science behind epigenetic clocks and how simple, accessible interventions can lead to profound changes in your health span. Tune in to learn how you can take control of your aging process and improve your overall well-being. #HealthyAging #Epigenetics #LifestyleChanges https://www.youtube-nocookie.com/embed/7BYvkN3hZhc 2399 2025-08-05T01:00:06.000Z 2026-10-22T18:54:04.200Z https://longevityharbor.com/de/watch/7BYvkN3hZhc How Fast Are You Really Ageing? The Science Behind Epigenetic Clocks https://i.ytimg.com/vi/7BYvkN3hZhc/hqdefault.jpg In this episode of "The Science of Turning Back Time," host Charmaine Shepherd delves into the fascinating world of biological aging with Dr. Varun Dwaraka, head of bioinformatics at True Diagnostics. Discover how lifestyle changes, such as diet, exercise, and stress management, can significantly impact your biological age. Dr. Dwaraka shares insights on the science behind epigenetic clocks and how simple, accessible interventions can lead to profound changes in your health span. Tune in to learn how you can take control of your aging process and improve your overall well-being. #HealthyAging #Epigenetics #LifestyleChanges https://www.youtube-nocookie.com/embed/7BYvkN3hZhc 2399 2025-08-05T01:00:06.000Z 2026-10-22T18:54:04.200Z https://longevityharbor.com/en/watch/7Cy6CaTeTpA The Science of INTERMITTENT FASTING: What New Research Shows https://i.ytimg.com/vi/7Cy6CaTeTpA/hqdefault.jpg Visit Dr. Stengler’s Website: https://drstengler.com/ In this video, Dr. Stengler discusses the latest research regarding the benefits of fasting, specifically intermittent fasting, for overall health and weight loss. He touches on how intermittent fasting can affect weight and the importance of understanding calorie restriction. Learn how to adopt a healthy lifestyle through fasting! CHAPTERS 00:00 Is Intermittent Fasting Really That Good for You? 00:21 Calorie Restriction vs. Intermittent Fasting 01:13 3 Types of Intermittent Fasting Explained 01:47 Time-Restricted Eating: The Most Practical Option 02:10 Chrononutrition: Why Meal Timing Matters 02:40 What Happens in the Body During Fasting? 03:02 Cellular and Metabolic Benefits of Fasting 03:45 Cardiovascular, Brain, and Cancer Support 04:05 Microbiome and Weight Loss Benefits 04:35 Choosing the Right Fasting Approach for You 04:48 Important Considerations and Common Pitfalls 05:42 Does Fasting Really Slow Aging? 06:12 Final Thoughts on Longevity and Human Research 🔔𝐃𝐨𝐧'𝐭 𝐟𝐨𝐫𝐠𝐞𝐭 𝐭𝐨 𝐬𝐮𝐛𝐬𝐜𝐫𝐢𝐛𝐞 𝐭𝐨 𝐦𝐲 𝐜𝐡𝐚𝐧𝐧𝐞𝐥 𝐟𝐨𝐫 𝐦𝐨𝐫𝐞 𝐮𝐩𝐝𝐚𝐭𝐞𝐬. https://www.youtube.com/@DrMarkStengler/?sub_confirmation=1 🔗 Stay Connected With Me. Facebook: https://www.facebook.com/markstengler Instagram: https://www.instagram.com/markstengler/ Website: http://drstengler.com/ ============================= 🎬Suggested videos for you: 👉 https://youtu.be/OFIDLvYQA74 👉 https://youtu.be/m4r04zIasbQ 👉 https://youtu.be/_RgeZ1XRzJ8 👉 https://youtu.be/JP0JJ-drPog 👉 https://youtu.be/JLgwCRtFT2Y 👉 https://youtu.be/HsV-mkxC274 👉 https://youtu.be/yTHvZu301Q0 👉 https://youtu.be/CH8dei4SbNY ================================= ✅ About Dr. Mark Stengler. Welcome to my natural health channel, Dr. Mark Stengler! I’m Dr. Mark, a Naturopathic Medical Doctor and best-selling author with nearly 30 years of experience in integrative medicine. Here, I share expert insights on natural health, nutrition, and the power of integrative medicine—blendi https://www.youtube-nocookie.com/embed/7Cy6CaTeTpA 402 2025-08-16T13:00:13.000Z 2026-10-22T19:32:31.911Z https://longevityharbor.com/de/watch/7Cy6CaTeTpA The Science of INTERMITTENT FASTING: What New Research Shows https://i.ytimg.com/vi/7Cy6CaTeTpA/hqdefault.jpg Visit Dr. Stengler’s Website: https://drstengler.com/ In this video, Dr. Stengler discusses the latest research regarding the benefits of fasting, specifically intermittent fasting, for overall health and weight loss. He touches on how intermittent fasting can affect weight and the importance of understanding calorie restriction. Learn how to adopt a healthy lifestyle through fasting! CHAPTERS 00:00 Is Intermittent Fasting Really That Good for You? 00:21 Calorie Restriction vs. Intermittent Fasting 01:13 3 Types of Intermittent Fasting Explained 01:47 Time-Restricted Eating: The Most Practical Option 02:10 Chrononutrition: Why Meal Timing Matters 02:40 What Happens in the Body During Fasting? 03:02 Cellular and Metabolic Benefits of Fasting 03:45 Cardiovascular, Brain, and Cancer Support 04:05 Microbiome and Weight Loss Benefits 04:35 Choosing the Right Fasting Approach for You 04:48 Important Considerations and Common Pitfalls 05:42 Does Fasting Really Slow Aging? 06:12 Final Thoughts on Longevity and Human Research 🔔𝐃𝐨𝐧'𝐭 𝐟𝐨𝐫𝐠𝐞𝐭 𝐭𝐨 𝐬𝐮𝐛𝐬𝐜𝐫𝐢𝐛𝐞 𝐭𝐨 𝐦𝐲 𝐜𝐡𝐚𝐧𝐧𝐞𝐥 𝐟𝐨𝐫 𝐦𝐨𝐫𝐞 𝐮𝐩𝐝𝐚𝐭𝐞𝐬. https://www.youtube.com/@DrMarkStengler/?sub_confirmation=1 🔗 Stay Connected With Me. Facebook: https://www.facebook.com/markstengler Instagram: https://www.instagram.com/markstengler/ Website: http://drstengler.com/ ============================= 🎬Suggested videos for you: 👉 https://youtu.be/OFIDLvYQA74 👉 https://youtu.be/m4r04zIasbQ 👉 https://youtu.be/_RgeZ1XRzJ8 👉 https://youtu.be/JP0JJ-drPog 👉 https://youtu.be/JLgwCRtFT2Y 👉 https://youtu.be/HsV-mkxC274 👉 https://youtu.be/yTHvZu301Q0 👉 https://youtu.be/CH8dei4SbNY ================================= ✅ About Dr. Mark Stengler. Welcome to my natural health channel, Dr. Mark Stengler! I’m Dr. Mark, a Naturopathic Medical Doctor and best-selling author with nearly 30 years of experience in integrative medicine. Here, I share expert insights on natural health, nutrition, and the power of integrative medicine—blendi https://www.youtube-nocookie.com/embed/7Cy6CaTeTpA 402 2025-08-16T13:00:13.000Z 2026-10-22T19:32:31.911Z https://longevityharbor.com/en/watch/7E_zjimq7tU NMN as a NAD+ precursor: a video description on cellular energy and aging https://i.ytimg.com/vi/7E_zjimq7tU/hqdefault.jpg A video description says NMN is a natural molecule cells convert into NAD+, a supply used for cellular energy, DNA repair and metabolism. It notes NAD+ tends to decline with age and that NMN is being studied, not shown, for energy, metabolic health, recovery, cognition and healthy aging. https://www.youtube-nocookie.com/embed/7E_zjimq7tU 102 2026-10-15T12:15:21.000Z 2026-10-22T19:35:52.454Z https://longevityharbor.com/de/watch/7E_zjimq7tU NMN als NAD+-Vorstufe: eine Videobeschreibung zu Zellenergie und Altern https://i.ytimg.com/vi/7E_zjimq7tU/hqdefault.jpg Eine Videobeschreibung erklärt, NMN sei ein natürliches Molekül, das Zellen in NAD+ umwandeln; NAD+ werde für Zellenergie, DNA-Reparatur und Stoffwechsel genutzt. Sie erwähnt, dass NAD+ mit dem Alter tendenziell sinkt, und dass NMN für Energie, Stoffwechselgesundheit, Erholung, Kognition und gesundes Altern untersucht wird – nicht, dass dies belegt ist. https://www.youtube-nocookie.com/embed/7E_zjimq7tU 102 2026-10-15T12:15:21.000Z 2026-10-22T19:35:52.454Z https://longevityharbor.com/en/watch/7GKWADS0Xso Why You Keep Waking Up at 3AM – Doctor Explains https://i.ytimg.com/vi/7GKWADS0Xso/hqdefault.jpg Why do you keep waking up at 3AM? It might not be stress or anxiety—it could be your cortisol rhythm. In this video, I break down the science behind early-morning wakeups, how your body’s natural hormone cycles work, and what you can do to get back to deeper, uninterrupted sleep. ✅ What we cover: – How cortisol normally rises between 2–4 AM – What triggers an early cortisol spike (stress, caffeine, low blood sugar, overtraining) – Simple strategies to improve your sleep rhythm 📌 If you’re dealing with consistent 3AM wake-ups, this one’s for you. 📲 Follow for more doctor-backed sleep and performance tips. #SleepHealth #Cortisol #CircadianRhythm #3AMWakeUp #DoctorExplains #YouTubeShorts #Longevity #HealthOptimization https://www.youtube-nocookie.com/embed/7GKWADS0Xso 124 2025-08-07T00:11:59.000Z 2026-10-22T19:43:49.890Z https://longevityharbor.com/de/watch/7GKWADS0Xso Why You Keep Waking Up at 3AM – Doctor Explains https://i.ytimg.com/vi/7GKWADS0Xso/hqdefault.jpg Why do you keep waking up at 3AM? It might not be stress or anxiety—it could be your cortisol rhythm. In this video, I break down the science behind early-morning wakeups, how your body’s natural hormone cycles work, and what you can do to get back to deeper, uninterrupted sleep. ✅ What we cover: – How cortisol normally rises between 2–4 AM – What triggers an early cortisol spike (stress, caffeine, low blood sugar, overtraining) – Simple strategies to improve your sleep rhythm 📌 If you’re dealing with consistent 3AM wake-ups, this one’s for you. 📲 Follow for more doctor-backed sleep and performance tips. #SleepHealth #Cortisol #CircadianRhythm #3AMWakeUp #DoctorExplains #YouTubeShorts #Longevity #HealthOptimization https://www.youtube-nocookie.com/embed/7GKWADS0Xso 124 2025-08-07T00:11:59.000Z 2026-10-22T19:43:49.890Z https://longevityharbor.com/en/watch/7K2ieJwyJro Video description: NMN as a precursor the body can use to produce NAD⁺ https://i.ytimg.com/vi/7K2ieJwyJro/hqdefault.jpg The description says NMN is a naturally occurring molecule and a precursor the body can use to produce NAD⁺, a coenzyme involved in cellular energy metabolism. It calls NMN an interesting area of healthy-aging research. https://www.youtube-nocookie.com/embed/7K2ieJwyJro 124 2026-09-25T10:04:40.000Z 2026-10-22T21:50:29.303Z https://longevityharbor.com/de/watch/7K2ieJwyJro Videobeschreibung: NMN als Vorstufe, die der Körper zur NAD⁺-Bildung nutzen kann https://i.ytimg.com/vi/7K2ieJwyJro/hqdefault.jpg Die Beschreibung nennt NMN ein natürlich vorkommendes Molekül und eine Vorstufe, die der Körper zur Bildung von NAD⁺ nutzen kann, einem Coenzym im zellulären Energiestoffwechsel. NMN sei ein interessantes Forschungsfeld zum gesunden Altern. https://www.youtube-nocookie.com/embed/7K2ieJwyJro 124 2026-09-25T10:04:40.000Z 2026-10-22T21:50:29.303Z https://longevityharbor.com/en/watch/7Kfpfr8RrMc Video description: cellular senescence, 'zombie cells' and proposed anti-aging targets https://i.ytimg.com/vi/7Kfpfr8RrMc/hqdefault.jpg The description says the episode explains cellular senescence, in which damaged cells stop dividing but do not die, and links these accumulating cells to inflammation and age-related diseases. It also says senolytics, senomorphics and regenerative medicine are being researched as possible anti-aging approaches. https://www.youtube-nocookie.com/embed/7Kfpfr8RrMc 574 2026-07-04T04:00:07.000Z 2026-10-22T23:41:20.492Z https://longevityharbor.com/de/watch/7Kfpfr8RrMc Videobeschreibung: Zelluläre Seneszenz, „Zombiezellen“ und vorgeschlagene Anti-Aging-Ziele https://i.ytimg.com/vi/7Kfpfr8RrMc/hqdefault.jpg Laut Beschreibung erklärt die Episode die zelluläre Seneszenz: geschädigte Zellen teilen sich nicht mehr, sterben aber nicht ab. Diese sich anhäufenden Zellen werden mit Entzündung und altersbezogenen Krankheiten verbunden. Zudem werden Senolytika, Senomorphika und regenerative Medizin als mögliche Anti-Aging-Ansätze in der Forschung genannt. https://www.youtube-nocookie.com/embed/7Kfpfr8RrMc 574 2026-07-04T04:00:07.000Z 2026-10-22T23:41:20.492Z https://longevityharbor.com/en/watch/7KnrZSGkxao Biologisches Alter halbiert! https://i.ytimg.com/vi/7KnrZSGkxao/hqdefault.jpg In den heutigen Longevity News geht es um eine neue Studie, in der das biologische Alter innerhalb von 12 Monaten halbiert wurde, um Longevity Island, Prophylaxe gegen graue Haare, die Vorankündigung der Detox Serie auf Epigenetik TV uvm. - Studie Longevinaut: https://www.extendedlongevity.com/general-8 - Epigenetik TV mit Thiemo Osterhaus: https://epi-genes.com/epigenetikTVepisode/Thiemo-Osterhaus-Hormone-Pflanzenstoffe-und-Longevity.aspx - Entschlüssle deine DNA mit EpiGenes: https://epi-genes.com/myGene.aspx - Werde Longevity Coach: https://www.inex-health.com/longevity-coach https://www.youtube-nocookie.com/embed/7KnrZSGkxao 1473 2023-07-13T12:56:51.000Z 2026-10-22T17:11:32.783Z https://longevityharbor.com/de/watch/7KnrZSGkxao Biologisches Alter halbiert! https://i.ytimg.com/vi/7KnrZSGkxao/hqdefault.jpg In den heutigen Longevity News geht es um eine neue Studie, in der das biologische Alter innerhalb von 12 Monaten halbiert wurde, um Longevity Island, Prophylaxe gegen graue Haare, die Vorankündigung der Detox Serie auf Epigenetik TV uvm. - Studie Longevinaut: https://www.extendedlongevity.com/general-8 - Epigenetik TV mit Thiemo Osterhaus: https://epi-genes.com/epigenetikTVepisode/Thiemo-Osterhaus-Hormone-Pflanzenstoffe-und-Longevity.aspx - Entschlüssle deine DNA mit EpiGenes: https://epi-genes.com/myGene.aspx - Werde Longevity Coach: https://www.inex-health.com/longevity-coach https://www.youtube-nocookie.com/embed/7KnrZSGkxao 1473 2023-07-13T12:56:51.000Z 2026-10-22T17:11:32.783Z https://longevityharbor.com/en/watch/7MBlknsRvyQ Video description: worm-model molecule search claims molecules outperform rapamycin https://i.ytimg.com/vi/7MBlknsRvyQ/hqdefault.jpg The description presents Ora Biomedical's Wormbot as a high-throughput, unbiased search for longevity interventions in worms, including the Million Molecule Challenge and molecules said to outperform rapamycin. It also describes a pivot to radiation resistance for astronauts, pilots and human health. These are creator claims in a description; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/7MBlknsRvyQ 4142 2025-11-29T14:00:12.000Z 2026-10-23T03:23:11.546Z https://longevityharbor.com/de/watch/7MBlknsRvyQ Videobeschreibung: Molekülsuche im Wurmmodell will Rapamycin übertreffen https://i.ytimg.com/vi/7MBlknsRvyQ/hqdefault.jpg Die Beschreibung stellt Ora Biomedicals Wormbot als hochdurchsatzfähige, unvoreingenommene Suche nach Langlebigkeitsinterventionen im Wurm dar, einschließlich der Million Molecule Challenge und Molekülen, die Rapamycin übertreffen sollen. Zudem wird eine Hinwendung zur Strahlenresistenz für Astronauten, Piloten und die menschliche Gesundheit beschrieben. Das sind Angaben des Erstellers in einer Beschreibung; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/7MBlknsRvyQ 4142 2025-11-29T14:00:12.000Z 2026-10-23T03:23:11.546Z https://longevityharbor.com/en/watch/7OBwxnIKkcs Video description: daily stretching and healthy aging claims https://i.ytimg.com/vi/7OBwxnIKkcs/hqdefault.jpg The description says research suggests regular stretching may support mobility, flexibility and physical function, and that consistency matters more than intensity. It gives no studies, numbers or outcomes and is educational only. https://www.youtube-nocookie.com/embed/7OBwxnIKkcs 1302 2026-07-25T17:17:27.000Z 2026-10-22T23:22:39.033Z https://longevityharbor.com/de/watch/7OBwxnIKkcs Videobeschreibung: Tägliches Dehnen und Aussagen zum gesunden Altern https://i.ytimg.com/vi/7OBwxnIKkcs/hqdefault.jpg Die Beschreibung sagt, Forschung lege nahe, dass regelmäßiges Dehnen Beweglichkeit, Flexibilität und körperliche Funktion unterstützen könnte, und dass Beständigkeit wichtiger sei als Intensität. Studien, Zahlen oder Ergebnisse nennt sie nicht; sie dient nur der Bildung. https://www.youtube-nocookie.com/embed/7OBwxnIKkcs 1302 2026-07-25T17:17:27.000Z 2026-10-22T23:22:39.033Z https://longevityharbor.com/en/watch/7PS4bmzhbHY Nir Barzilai at ARDD2023 - Longevity Medicine Day: From geroscience to gerotherapeutics https://i.ytimg.com/vi/7PS4bmzhbHY/hqdefault.jpg Nir Barzilai, Albert Einstein College of Medicine, USA presents at the 10th Aging Research and Drug Discovery conference - Longevity Medicine Day: From geroscience to gerotherapeutics https://www.youtube-nocookie.com/embed/7PS4bmzhbHY 1708 2023-10-26T18:48:30.000Z 2026-10-22T19:32:34.336Z https://longevityharbor.com/de/watch/7PS4bmzhbHY Nir Barzilai at ARDD2023 - Longevity Medicine Day: From geroscience to gerotherapeutics https://i.ytimg.com/vi/7PS4bmzhbHY/hqdefault.jpg Nir Barzilai, Albert Einstein College of Medicine, USA presents at the 10th Aging Research and Drug Discovery conference - Longevity Medicine Day: From geroscience to gerotherapeutics https://www.youtube-nocookie.com/embed/7PS4bmzhbHY 1708 2023-10-26T18:48:30.000Z 2026-10-22T19:32:34.336Z https://longevityharbor.com/en/watch/7SPdpGoCAh4 Creator describes her own senolytic routine with fisetin and quercetin https://i.ytimg.com/vi/7SPdpGoCAh4/hqdefault.jpg In the description, the creator says she is doing a course of the senolytics fisetin and quercetin to remove senescent cells and names further supplements she takes; she states she is not a doctor and gives no medical advice. https://www.youtube-nocookie.com/embed/7SPdpGoCAh4 749 2026-09-19T15:45:05.000Z 2026-10-22T22:04:45.334Z https://longevityharbor.com/de/watch/7SPdpGoCAh4 Creatorin beschreibt ihre eigene Senolytika-Routine mit Fisetin und Quercetin https://i.ytimg.com/vi/7SPdpGoCAh4/hqdefault.jpg In der Beschreibung sagt die Creatorin, sie mache eine Kur mit den Senolytika Fisetin und Quercetin, um seneszente Zellen zu entfernen, und nennt weitere Supplements, die sie nimmt; sie betont, keine Ärztin zu sein und keine medizinischen Ratschläge zu geben. https://www.youtube-nocookie.com/embed/7SPdpGoCAh4 749 2026-09-19T15:45:05.000Z 2026-10-22T22:04:45.334Z https://longevityharbor.com/en/watch/7TLTN69d_gM Biological age tests from 40: what the description says https://i.ytimg.com/vi/7TLTN69d_gM/hqdefault.jpg The description presents three ways to estimate biological age: epigenetic clocks, blood-based markers and telomere tests. It calls GrimAge most accurate for predicting lifespan and telomere tests weakest as a single value. https://www.youtube-nocookie.com/embed/7TLTN69d_gM 530 2026-06-10T21:27:33.000Z 2026-10-23T00:00:21.248Z https://longevityharbor.com/de/watch/7TLTN69d_gM Biologische Alterstests ab 40: Was die Beschreibung sagt https://i.ytimg.com/vi/7TLTN69d_gM/hqdefault.jpg Die Beschreibung stellt drei Wege zur Schätzung des biologischen Alters vor: epigenetische Uhren, Blutmarker und Telomertests. GrimAge nennt sie am genauesten für die Lebenszeit-Vorhersage, Telomertests als Einzelwert am schwächsten. https://www.youtube-nocookie.com/embed/7TLTN69d_gM 530 2026-06-10T21:27:33.000Z 2026-10-23T00:00:21.248Z https://longevityharbor.com/en/watch/7WYafh0gX6s Rapamycin and ovarian reserve: animal findings, experimental human research https://i.ytimg.com/vi/7WYafh0gX6s/hqdefault.jpg The description says rapamycin, an mTOR inhibitor, is being studied for slowing activation of primordial follicles. In animals it preserved ovarian reserve and delayed markers of ovarian aging; in humans, research is still experimental, with timing, dosage and safety open. https://www.youtube-nocookie.com/embed/7WYafh0gX6s 140 2026-02-25T12:00:10.000Z 2026-10-23T02:20:06.368Z https://longevityharbor.com/de/watch/7WYafh0gX6s Rapamycin und Ovarreserve: Tierbefunde, experimentelle Forschung am Menschen https://i.ytimg.com/vi/7WYafh0gX6s/hqdefault.jpg Laut Beschreibung wird Rapamycin, ein mTOR-Hemmer, darauf untersucht, die Aktivierung primordialer Follikel zu verlangsamen. Bei Tieren erhielt es die Ovarreserve und verzögerte Marker der Ovaralterung; beim Menschen ist die Forschung noch experimentell, Zeitpunkt, Dosierung und Sicherheit sind offen. https://www.youtube-nocookie.com/embed/7WYafh0gX6s 140 2026-02-25T12:00:10.000Z 2026-10-23T02:20:06.368Z https://longevityharbor.com/en/watch/7ZtVbNfAAnQ Description presents epigenetic age as a biomarker for aging and disease risk https://i.ytimg.com/vi/7ZtVbNfAAnQ/hqdefault.jpg The description presents epigenetic age as a biomarker for aging and disease risk and says diet affects genes; it offers no study data, and the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/7ZtVbNfAAnQ 140 2026-04-30T11:01:30.000Z 2026-10-23T01:19:42.836Z https://longevityharbor.com/de/watch/7ZtVbNfAAnQ Beschreibung stellt epigenetisches Alter als Biomarker für Altern und Krankheitsrisiko vor https://i.ytimg.com/vi/7ZtVbNfAAnQ/hqdefault.jpg Die Beschreibung stellt epigenetisches Alter als Biomarker für Altern und Krankheitsrisiko vor und sagt, Ernährung beeinflusse Gene; sie liefert keine Studiendaten, und Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/7ZtVbNfAAnQ 140 2026-04-30T11:01:30.000Z 2026-10-23T01:19:42.836Z https://longevityharbor.com/en/watch/7hac8krfS_s Video description: senescent cells and senolytics explained https://i.ytimg.com/vi/7hac8krfS_s/hqdefault.jpg The creator says the clip explains senescent cells, why their buildup is said to speed aging, and how senolytics are claimed to clear them while sparing healthy cells. https://www.youtube-nocookie.com/embed/7hac8krfS_s 103 2026-07-05T13:33:29.000Z 2026-10-22T23:39:33.248Z https://longevityharbor.com/de/watch/7hac8krfS_s Videobeschreibung: seneszente Zellen und Senolytika erklärt https://i.ytimg.com/vi/7hac8krfS_s/hqdefault.jpg Der Ersteller sagt, der Clip erkläre seneszente Zellen, warum ihre Anhäufung das Altern beschleunigen soll und wie Senolytika sie angeblich beseitigen, ohne gesunde Zellen zu schädigen. https://www.youtube-nocookie.com/embed/7hac8krfS_s 103 2026-07-05T13:33:29.000Z 2026-10-22T23:39:33.248Z https://longevityharbor.com/en/watch/7jU7LCXTS2o NEW Report Alert: Organ system clock developed with Yale https://i.ytimg.com/vi/7jU7LCXTS2o/hqdefault.jpg Marking a milestone development in epigenetic research and clinical health applications, laboratory TruDiagnostic is launching the first ever, epigenetic aging analysis of individual organ systems, using validated and system-specific trained clocks. These algorithms, developed by scientists at Yale University, were previously released in biology journal bioRxiv as a preprint, with peer reviewed publications expected later this year. Now known as SYMPHONYAge (System Methylation Proxy of Heterogeneous Organ Years), this collection of system-specific clocks provides a new way of looking at aging by examining how different parts of the body decline independently, and synchronously, over time. Due to lifestyle and dietary choices, researchers explain that organ systems age differently in a single body, and that disease-related risks can be calculated by examining 11 major systems and their biological effect on one another. This includes: Lung Age, Heart Age, Brain Age, Hormone Age, Metabolic Age, Musculoskeletal Age, Blood Age, Liver Age, Inflammation Age, Kidney Age, and Immune System Age. While some biological age tests already claim to predict the extent of aging of various organ systems, SYMPHONYAge is notably different in scope, validation, and associations with various health outcomes. It is also the only published clock which gives organ specific aging information. TruDiagnostic has an exclusive license on the use of these algorithms which were previously called Systems Clock during earlier stages of research and development. Researchers explain that SYMPHONYAge differs from its early-stage predecessors in the following ways. More clocks: SYMPHONYAge reports on 11 (opposed to nine) organ systems, using system-specific clocks. Additionally, it also predicts one integrated whole-body clock that uses the 11 system-specific clocks as input. More training data: SYMPHONYAge uses 133 molecular, cellular, and functional biomarkers for modeling organ system ages, while old organ clocks only used 59 biomarkers. The https://www.youtube-nocookie.com/embed/7jU7LCXTS2o 2061 2024-06-27T16:18:50.000Z 2026-10-22T18:32:06.777Z https://longevityharbor.com/de/watch/7jU7LCXTS2o NEW Report Alert: Organ system clock developed with Yale https://i.ytimg.com/vi/7jU7LCXTS2o/hqdefault.jpg Marking a milestone development in epigenetic research and clinical health applications, laboratory TruDiagnostic is launching the first ever, epigenetic aging analysis of individual organ systems, using validated and system-specific trained clocks. These algorithms, developed by scientists at Yale University, were previously released in biology journal bioRxiv as a preprint, with peer reviewed publications expected later this year. Now known as SYMPHONYAge (System Methylation Proxy of Heterogeneous Organ Years), this collection of system-specific clocks provides a new way of looking at aging by examining how different parts of the body decline independently, and synchronously, over time. Due to lifestyle and dietary choices, researchers explain that organ systems age differently in a single body, and that disease-related risks can be calculated by examining 11 major systems and their biological effect on one another. This includes: Lung Age, Heart Age, Brain Age, Hormone Age, Metabolic Age, Musculoskeletal Age, Blood Age, Liver Age, Inflammation Age, Kidney Age, and Immune System Age. While some biological age tests already claim to predict the extent of aging of various organ systems, SYMPHONYAge is notably different in scope, validation, and associations with various health outcomes. It is also the only published clock which gives organ specific aging information. TruDiagnostic has an exclusive license on the use of these algorithms which were previously called Systems Clock during earlier stages of research and development. Researchers explain that SYMPHONYAge differs from its early-stage predecessors in the following ways. More clocks: SYMPHONYAge reports on 11 (opposed to nine) organ systems, using system-specific clocks. Additionally, it also predicts one integrated whole-body clock that uses the 11 system-specific clocks as input. More training data: SYMPHONYAge uses 133 molecular, cellular, and functional biomarkers for modeling organ system ages, while old organ clocks only used 59 biomarkers. The https://www.youtube-nocookie.com/embed/7jU7LCXTS2o 2061 2024-06-27T16:18:50.000Z 2026-10-22T18:32:06.777Z https://longevityharbor.com/en/watch/7ksKFjWt9HI Video description: epigenetic clocks and intrinsic capacity at a 2026 summit session https://i.ytimg.com/vi/7ksKFjWt9HI/hqdefault.jpg The description says Dr. David Furman's Milan Longevity Summit 2026 session covers epigenetic clocks as tools to measure intrinsic capacity, combining epigenetics, systems immunology, artificial intelligence and large human data. https://www.youtube-nocookie.com/embed/7ksKFjWt9HI 862 2026-08-08T08:38:03.000Z 2026-10-22T23:09:16.831Z https://longevityharbor.com/de/watch/7ksKFjWt9HI Videobeschreibung: epigenetische Uhren und intrinsische Kapazität bei einer Summit-Sitzung 2026 https://i.ytimg.com/vi/7ksKFjWt9HI/hqdefault.jpg Laut Beschreibung behandelt die Sitzung von Dr. David Furman beim Milan Longevity Summit 2026 epigenetische Uhren als Werkzeuge zur Messung der intrinsischen Kapazität, unter Einbezug von Epigenetik, Systemimmunologie, künstlicher Intelligenz und großen menschlichen Daten. https://www.youtube-nocookie.com/embed/7ksKFjWt9HI 862 2026-08-08T08:38:03.000Z 2026-10-22T23:09:16.831Z https://longevityharbor.com/en/watch/7o6HXptQk1A Why Not All Circadian Disruption Is the Same https://i.ytimg.com/vi/7o6HXptQk1A/hqdefault.jpg We often think of circadian disruption as something big: jet lag, night shifts, or chronic insomnia. But some of the most powerful shifts I’ve seen clinically come from something much smaller: artificial evening light. Not just overhead lights. Not just blue light. Even low, ambient light from a phone screen or bedside lamp can nudge your biology in a new direction. During my Master’s research at Oxford’s Sleep and Circadian Neuroscience Institute, I studied what happens when we expose mice to just four hours of dim light in the evening. No drastic changes. Just a subtle shift: 20 lux, layered on top of their normal light–dark cycle. What we found was unexpected: 🔹 Alpha diversity increased; beta diversity stayed stable 🔹 Akkermansiaceae and Bifidobacteriaceae showed significant reduction. 🔹 Functions shifted more than composition (notably amino-acid and oxidative-stress pathways, with B-vitamin metabolism signals) 🔹 In mice, more evening light increased sleep; in humans, comparable evening light tends to delay melatonin and fragment or shorten sleep (Tähkämö et al., 2018; Cain et al., 2020) 🔹 No change in weight or daily intake In other words, not a collapse but a timing shift of clocks and feeding. These results mirror what I see in patients: a gradual misalignment between behavior and biology. Over time, that drift can affect gut health, energy, sleep quality, and inflammation (Tam et al., 2021). Other studies show that even warm evening light, at levels common in homes, can delay melatonin release and alter sleep patterns (Tähkämö et al., 2018; Cain et al., 2020). And the gut? It runs on time too. Meal timing influences microbial activity more than light itself, so pushing dinner late can shift metabolites and balance (Heddes et al., 2022; Lotti et al., 2023). We often talk about what people eat. But we rarely ask when or under what light. That’s where the new frontier of circadian and gut health begins: small, overlooked inputs that quietly reshape the system. Want to dive deeper into the study https://www.youtube-nocookie.com/embed/7o6HXptQk1A 95 2025-09-21T08:53:10.000Z 2026-10-22T18:54:00.934Z https://longevityharbor.com/de/watch/7o6HXptQk1A Why Not All Circadian Disruption Is the Same https://i.ytimg.com/vi/7o6HXptQk1A/hqdefault.jpg We often think of circadian disruption as something big: jet lag, night shifts, or chronic insomnia. But some of the most powerful shifts I’ve seen clinically come from something much smaller: artificial evening light. Not just overhead lights. Not just blue light. Even low, ambient light from a phone screen or bedside lamp can nudge your biology in a new direction. During my Master’s research at Oxford’s Sleep and Circadian Neuroscience Institute, I studied what happens when we expose mice to just four hours of dim light in the evening. No drastic changes. Just a subtle shift: 20 lux, layered on top of their normal light–dark cycle. What we found was unexpected: 🔹 Alpha diversity increased; beta diversity stayed stable 🔹 Akkermansiaceae and Bifidobacteriaceae showed significant reduction. 🔹 Functions shifted more than composition (notably amino-acid and oxidative-stress pathways, with B-vitamin metabolism signals) 🔹 In mice, more evening light increased sleep; in humans, comparable evening light tends to delay melatonin and fragment or shorten sleep (Tähkämö et al., 2018; Cain et al., 2020) 🔹 No change in weight or daily intake In other words, not a collapse but a timing shift of clocks and feeding. These results mirror what I see in patients: a gradual misalignment between behavior and biology. Over time, that drift can affect gut health, energy, sleep quality, and inflammation (Tam et al., 2021). Other studies show that even warm evening light, at levels common in homes, can delay melatonin release and alter sleep patterns (Tähkämö et al., 2018; Cain et al., 2020). And the gut? It runs on time too. Meal timing influences microbial activity more than light itself, so pushing dinner late can shift metabolites and balance (Heddes et al., 2022; Lotti et al., 2023). We often talk about what people eat. But we rarely ask when or under what light. That’s where the new frontier of circadian and gut health begins: small, overlooked inputs that quietly reshape the system. Want to dive deeper into the study https://www.youtube-nocookie.com/embed/7o6HXptQk1A 95 2025-09-21T08:53:10.000Z 2026-10-22T18:54:00.934Z https://longevityharbor.com/en/watch/7p5JMvy9Twg DMA drug mix with low-dose navitoclax in old mice: senescent and cancer cells https://i.ytimg.com/vi/7p5JMvy9Twg/hqdefault.jpg Per the description, a combination called DMA (dichloroacetate, metformin, 10-fold lower-dose navitoclax) targeted senescent and cancer cells in vitro and, in mice, improved performance after short dosing and extended lifespan after longer dosing. https://www.youtube-nocookie.com/embed/7p5JMvy9Twg 102 2026-08-03T15:25:19.000Z 2026-10-22T23:15:27.560Z https://longevityharbor.com/de/watch/7p5JMvy9Twg DMA-Wirkstoffmix mit niedrig dosiertem Navitoclax bei alten Mäusen: seneszente und Krebszellen https://i.ytimg.com/vi/7p5JMvy9Twg/hqdefault.jpg Laut Beschreibung zielte eine Kombination namens DMA (Dichloracetat, Metformin, zehnfach niedriger dosiertes Navitoclax) in vitro auf seneszente und Krebszellen und verbesserte bei Mäusen die Leistung nach kurzer Gabe sowie die Lebensspanne nach längerer Gabe. https://www.youtube-nocookie.com/embed/7p5JMvy9Twg 102 2026-08-03T15:25:19.000Z 2026-10-22T23:15:27.560Z https://longevityharbor.com/en/watch/7wr3n-eXakM Circadian Rhythm MASTERY: How to Sync Your Body Clock for Perfect Sleep https://i.ytimg.com/vi/7wr3n-eXakM/hqdefault.jpg Learn how to optimize your body's internal clock for better sleep, more energy, and improved health. This video reveals the science behind your circadian rhythm and provides actionable strategies to synchronize it with your lifestyle for optimal performance and well-being. Timestamps 0:00 - Introduction: Your body's internal orchestra conductor 0:30 - What is circadian rhythm? Understanding your biological clock 1:00 - How your circadian rhythm controls your sleep quality 1:30 - 7 warning signs your body clock is out of sync 3:00 - Science-backed strategies to reset and optimize your rhythm 4:00 - Conclusion: The lifelong benefits of circadian alignment. Join Our Sleep Science Community 🔔 Subscribe for weekly evidence-based sleep optimization videos 💬 Share your circadian challenges in the comments 👍 Like this video if you're ready to sync your body clock Sleep Better Tonight Try implementing consistent wake-up times (even on weekends) and morning sunlight exposure for just one week and notice how your energy levels and sleep quality improve! Scientific References 1. Roenneberg, T., & Merrow, M. (2016). The Circadian Clock and Human Health. Current Biology, 26(10), R432-R443. 2. Panda, S. (2016 ). Circadian physiology of metabolism. Science, 354(6315), 1008-1015. 3. Duffy, J. F., & Czeisler, C. A. (2009 ). Effect of Light on Human Circadian Physiology. Sleep Medicine Clinics, 4(2), 165-177. 4. Hatori, M., Gronfier, C., Van Gelder, R. N., et al. (2017 ). Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies. Disclaimer This video is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider before making changes to your sleep routine, especially if you have existing sleep disorders or health conditions. #CircadianRhythm #SleepScience #BodyClock #ChronoBiology #SleepOptimization #CircadianHealth #BlueLight #TimeRestriction #SleepHygiene #EvidenceBasedHealth https://www.youtube-nocookie.com/embed/7wr3n-eXakM 392 2025-07-02T00:30:10.000Z 2026-10-22T18:54:02.018Z https://longevityharbor.com/de/watch/7wr3n-eXakM Circadian Rhythm MASTERY: How to Sync Your Body Clock for Perfect Sleep https://i.ytimg.com/vi/7wr3n-eXakM/hqdefault.jpg Learn how to optimize your body's internal clock for better sleep, more energy, and improved health. This video reveals the science behind your circadian rhythm and provides actionable strategies to synchronize it with your lifestyle for optimal performance and well-being. Timestamps 0:00 - Introduction: Your body's internal orchestra conductor 0:30 - What is circadian rhythm? Understanding your biological clock 1:00 - How your circadian rhythm controls your sleep quality 1:30 - 7 warning signs your body clock is out of sync 3:00 - Science-backed strategies to reset and optimize your rhythm 4:00 - Conclusion: The lifelong benefits of circadian alignment. Join Our Sleep Science Community 🔔 Subscribe for weekly evidence-based sleep optimization videos 💬 Share your circadian challenges in the comments 👍 Like this video if you're ready to sync your body clock Sleep Better Tonight Try implementing consistent wake-up times (even on weekends) and morning sunlight exposure for just one week and notice how your energy levels and sleep quality improve! Scientific References 1. Roenneberg, T., & Merrow, M. (2016). The Circadian Clock and Human Health. Current Biology, 26(10), R432-R443. 2. Panda, S. (2016 ). Circadian physiology of metabolism. Science, 354(6315), 1008-1015. 3. Duffy, J. F., & Czeisler, C. A. (2009 ). Effect of Light on Human Circadian Physiology. Sleep Medicine Clinics, 4(2), 165-177. 4. Hatori, M., Gronfier, C., Van Gelder, R. N., et al. (2017 ). Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies. Disclaimer This video is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider before making changes to your sleep routine, especially if you have existing sleep disorders or health conditions. #CircadianRhythm #SleepScience #BodyClock #ChronoBiology #SleepOptimization #CircadianHealth #BlueLight #TimeRestriction #SleepHygiene #EvidenceBasedHealth https://www.youtube-nocookie.com/embed/7wr3n-eXakM 392 2025-07-02T00:30:10.000Z 2026-10-22T18:54:02.018Z https://longevityharbor.com/en/watch/7yNvz_0Q1eQ 357 ‒ A new era of longevity science: models of aging, rapamycin trials, biological clocks, & more https://i.ytimg.com/vi/7yNvz_0Q1eQ/hqdefault.jpg Brian Kennedy is a renowned biologist, leader in aging research, & director of the Center for Healthy Longevity at the National University of Singapore. In this episode, Brian shares insights from ongoing human aging studies, including clinical trials of rapamycin & how dosing strategies, timing, & exercise may influence outcomes. He presents two key models of aging—one as a linear accumulation of biological decline & the other as an exponential rise in mortality risk—& explains why traditional models of aging fall short. He also explains why most current aging biomarkers lack clinical utility & describes how his team is working to develop a more actionable biological clock. Additional topics include the potential of compounds like alpha-ketoglutarate, urolithin A, & NAD boosters, along with how lifestyle interventions—such as VO2 max training, strength building, & the use of GLP-1 & SGLT2 drugs—may contribute to longer, healthier lives. View show notes here: https://bit.ly/44ShpRB Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ 0:00:00-Intro 0:01:15-Brian’s journey from the Buck Institute to Singapore, & the global evolution of aging research 0:09:12-Rethinking the biology of aging 0:14:13-How inflammation & mTOR signaling may play a central, causal role in aging 0:18:00-Biological role of mTOR in aging, & the potential of rapamycin to slow aging & enhance immune resilience 0:23:32-Aging as a linear decline in resilience overlaid with non-linear health fluctuations 0:36:03-Speculating on the future of longevity: slowing biological aging through noise reduction & reprogramming 0:42:18-The role of the epigenome in aging, & the limits of methylation clocks 0:47:14-Balancing the quest for immortality with the urgent need to improve late-life healthspan 0:52:16-Comparing the big 4 chronic diseases: which are the most inevitable & modifiable? 0:57:27-Exploring potential benefits of rapamycin: how Brian https://www.youtube-nocookie.com/embed/7yNvz_0Q1eQ 7952 2025-07-21T04:00:08.000Z 2026-10-22T17:43:41.729Z https://longevityharbor.com/de/watch/7yNvz_0Q1eQ 357 ‒ A new era of longevity science: models of aging, rapamycin trials, biological clocks, & more https://i.ytimg.com/vi/7yNvz_0Q1eQ/hqdefault.jpg Brian Kennedy is a renowned biologist, leader in aging research, & director of the Center for Healthy Longevity at the National University of Singapore. In this episode, Brian shares insights from ongoing human aging studies, including clinical trials of rapamycin & how dosing strategies, timing, & exercise may influence outcomes. He presents two key models of aging—one as a linear accumulation of biological decline & the other as an exponential rise in mortality risk—& explains why traditional models of aging fall short. He also explains why most current aging biomarkers lack clinical utility & describes how his team is working to develop a more actionable biological clock. Additional topics include the potential of compounds like alpha-ketoglutarate, urolithin A, & NAD boosters, along with how lifestyle interventions—such as VO2 max training, strength building, & the use of GLP-1 & SGLT2 drugs—may contribute to longer, healthier lives. View show notes here: https://bit.ly/44ShpRB Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ 0:00:00-Intro 0:01:15-Brian’s journey from the Buck Institute to Singapore, & the global evolution of aging research 0:09:12-Rethinking the biology of aging 0:14:13-How inflammation & mTOR signaling may play a central, causal role in aging 0:18:00-Biological role of mTOR in aging, & the potential of rapamycin to slow aging & enhance immune resilience 0:23:32-Aging as a linear decline in resilience overlaid with non-linear health fluctuations 0:36:03-Speculating on the future of longevity: slowing biological aging through noise reduction & reprogramming 0:42:18-The role of the epigenome in aging, & the limits of methylation clocks 0:47:14-Balancing the quest for immortality with the urgent need to improve late-life healthspan 0:52:16-Comparing the big 4 chronic diseases: which are the most inevitable & modifiable? 0:57:27-Exploring potential benefits of rapamycin: how Brian https://www.youtube-nocookie.com/embed/7yNvz_0Q1eQ 7952 2025-07-21T04:00:08.000Z 2026-10-22T17:43:41.729Z https://longevityharbor.com/en/watch/80IaqThlf0A Brad Stanfield on Rapamycin Longevity Series | Rapamycin, mTOR and the importance of muscle in life https://i.ytimg.com/vi/80IaqThlf0A/hqdefault.jpg Dr Brad Stanfield works as a medical doctor in New Zealand and beside his work in primary-care he has his own Youtube channel, in which he goes through the latest research and clinical guidelines on preventative medicine and longevity. In today’s podcast we are going to talk about Brad’s upcoming Rapamycin trial, the importance of muscle when we get older, sarcopenia and lots of other interesting longevity topics. 00:00 Intro 01:45 Common health problems in the clinic 04:01 When does muscle decline start? 05:09 How to minimize muscle decline 08:47 Low protein or high protein diet? 11:44 Animal or plant based protein? 14:08 Methionine restriction 15:23 Why Brad started his Rapamycin trial 16:04 Rapamycin and human research 17:35 Rapamycin, mTOR and muscle building 19:15 The Rapamycin trial design 21:21 Rapamycin blunts the effects of exercise? 22:28 Dose regime in the Rapamycin trial 23:56 Difference between the PEARL trial 24:39 Status of Brad's Rapamycin trial 26:38 Trial donation possibilities 29:13 Navigate better among all health claims 32:01 The evidence pyramid 34:36 Benefits of randomized controlled trials 39:38 Why Brad started his Youtube channel 40:51 Brad's supplement stack 48:25 The compound Taurine 50:05 Verify supplement quality and purity 51:09 Brad's view on Rapamycin 53:23 Rapamycin risks 55:05 Definition of blunt of exercise 55:40 Metformin have blunting effects of exercise 56:48 Weak points around Rapamycin 58:03 How well will Rapamycin translate to humans 59:07 The most promising longevity interventions 1:02:00 Brad's longevity interventions 1:05:03 How combine longevity interventions 1:07:17 How to find the mTOR sweet spot 1:11:07 Brad's longevity intervention when he is old 1:12:24 How to keep updated in the longevity field 1:12:50 People Brad follows Links - Brad Stanfield's Youtube https://www.youtube.com/@DrBradStanfield - Donate to Brad's Rapamycin clinical trial https://drstanfield.com/pages/ongoing-clinical-studies - Brad's MicroVitamin supplement https://drstanfield.com/products/mic https://www.youtube-nocookie.com/embed/80IaqThlf0A 4552 2023-07-11T08:48:00.000Z 2026-10-22T17:43:41.085Z https://longevityharbor.com/de/watch/80IaqThlf0A Brad Stanfield on Rapamycin Longevity Series | Rapamycin, mTOR and the importance of muscle in life https://i.ytimg.com/vi/80IaqThlf0A/hqdefault.jpg Dr Brad Stanfield works as a medical doctor in New Zealand and beside his work in primary-care he has his own Youtube channel, in which he goes through the latest research and clinical guidelines on preventative medicine and longevity. In today’s podcast we are going to talk about Brad’s upcoming Rapamycin trial, the importance of muscle when we get older, sarcopenia and lots of other interesting longevity topics. 00:00 Intro 01:45 Common health problems in the clinic 04:01 When does muscle decline start? 05:09 How to minimize muscle decline 08:47 Low protein or high protein diet? 11:44 Animal or plant based protein? 14:08 Methionine restriction 15:23 Why Brad started his Rapamycin trial 16:04 Rapamycin and human research 17:35 Rapamycin, mTOR and muscle building 19:15 The Rapamycin trial design 21:21 Rapamycin blunts the effects of exercise? 22:28 Dose regime in the Rapamycin trial 23:56 Difference between the PEARL trial 24:39 Status of Brad's Rapamycin trial 26:38 Trial donation possibilities 29:13 Navigate better among all health claims 32:01 The evidence pyramid 34:36 Benefits of randomized controlled trials 39:38 Why Brad started his Youtube channel 40:51 Brad's supplement stack 48:25 The compound Taurine 50:05 Verify supplement quality and purity 51:09 Brad's view on Rapamycin 53:23 Rapamycin risks 55:05 Definition of blunt of exercise 55:40 Metformin have blunting effects of exercise 56:48 Weak points around Rapamycin 58:03 How well will Rapamycin translate to humans 59:07 The most promising longevity interventions 1:02:00 Brad's longevity interventions 1:05:03 How combine longevity interventions 1:07:17 How to find the mTOR sweet spot 1:11:07 Brad's longevity intervention when he is old 1:12:24 How to keep updated in the longevity field 1:12:50 People Brad follows Links - Brad Stanfield's Youtube https://www.youtube.com/@DrBradStanfield - Donate to Brad's Rapamycin clinical trial https://drstanfield.com/pages/ongoing-clinical-studies - Brad's MicroVitamin supplement https://drstanfield.com/products/mic https://www.youtube-nocookie.com/embed/80IaqThlf0A 4552 2023-07-11T08:48:00.000Z 2026-10-22T17:43:41.085Z https://longevityharbor.com/en/watch/82_qcqwhnf4 My “Aging in Reverse” Secret ✨ | Cata-Kor NAD + NMN Supplement Review https://i.ytimg.com/vi/82_qcqwhnf4/hqdefault.jpg My secret to aging in reverse is @Cata-Kor USA ✨ #catakor #nad #nmn #supplementsthatwork #momlifehumor Link: https://urlgeni.us/AshleyCataKorSet https://www.youtube-nocookie.com/embed/82_qcqwhnf4 114 2026-06-24T01:00:30.000Z 2026-10-22T19:04:42.015Z https://longevityharbor.com/de/watch/82_qcqwhnf4 My “Aging in Reverse” Secret ✨ | Cata-Kor NAD + NMN Supplement Review https://i.ytimg.com/vi/82_qcqwhnf4/hqdefault.jpg My secret to aging in reverse is @Cata-Kor USA ✨ #catakor #nad #nmn #supplementsthatwork #momlifehumor Link: https://urlgeni.us/AshleyCataKorSet https://www.youtube-nocookie.com/embed/82_qcqwhnf4 114 2026-06-24T01:00:30.000Z 2026-10-22T19:04:42.015Z https://longevityharbor.com/en/watch/85jh-3lFpA4 KLRN SciTech Now Shorts: Rapamycin Research https://i.ytimg.com/vi/85jh-3lFpA4/hqdefault.jpg Aging decreases blood flow to the brain, impacting the progression of vascular-related diseases such as Alzheimer’s. Now, UT Health San Antonino researchers, working with other institutions, found that a particular drug can modify blood flow. And, that could be a boon to treating memory diseases. Learn more and watch full episodes at www.klrn.org/scitechnow https://www.youtube-nocookie.com/embed/85jh-3lFpA4 254 2020-04-18T23:17:31.000Z 2026-10-22T17:43:41.796Z https://longevityharbor.com/de/watch/85jh-3lFpA4 KLRN SciTech Now Shorts: Rapamycin Research https://i.ytimg.com/vi/85jh-3lFpA4/hqdefault.jpg Aging decreases blood flow to the brain, impacting the progression of vascular-related diseases such as Alzheimer’s. Now, UT Health San Antonino researchers, working with other institutions, found that a particular drug can modify blood flow. And, that could be a boon to treating memory diseases. Learn more and watch full episodes at www.klrn.org/scitechnow https://www.youtube-nocookie.com/embed/85jh-3lFpA4 254 2020-04-18T23:17:31.000Z 2026-10-22T17:43:41.796Z https://longevityharbor.com/en/watch/879LIpkxlh4 Dr. Joan Mannick — mTOR’s Role in Aging https://i.ytimg.com/vi/879LIpkxlh4/hqdefault.jpg During this episode of Longevity by Design, Dr. Joan Mannick explains how mTOR influences the aging process. She explains that this evolutionarily conserved protein is involved in several cellular functions in the body and acts on longevity-promoting pathways like autophagy. Dr. Mannick also discusses the connection between mTOR and the immune system, sharing her research on how low-dose mTOR inhibitors can upregulate antiviral immunity, creating an opportunity for more targeted vaccines for older adults. After extensive research on mTOR across many species, Dr. Mannick shares impressive insight into how mTOR inhibitors like rapamycin can promote longevity. Tune in to learn more about the latest research in the field. Intro: (00:00-1:20) Dr. Mannick’s background (1:20-6:52) What is mTOR → (6:53–10:15) How Rapamycin acts on mTOR → (10:16–15:17) When to treat with Rapamycin → (15:17–21:36) Dr. Mannick’s trials with rapalogs → (21:37–28:42) The future of Rapamycin → (28:42–31:02) Cautions of anti-aging therapies → (31:02–41:10) Top tip for healthspan → (41:10–41:45) Closing remarks (41:45–end) To learn more: https://hubs.li/Q01CQ86r0 — Let’s Connect! Instagram - https://www.instagram.com/insidetracker Twitter - https://twitter.com/InsideTracker Facebook - https://www.facebook.com/InsideTracker LinkedIn- https://www.linkedin.com/company/insidetracker/  TikTok- https://www.tiktok.com/@insidetracker_  Pinterest- https://www.pinterest.com/insidetracker/  Website - https://www.insidetracker.com/  In the Press - https://www.insidetracker.com/press-page/ https://www.youtube-nocookie.com/embed/879LIpkxlh4 2563 2023-02-22T15:42:07.000Z 2026-10-22T17:43:41.046Z https://longevityharbor.com/de/watch/879LIpkxlh4 Dr. Joan Mannick — mTOR’s Role in Aging https://i.ytimg.com/vi/879LIpkxlh4/hqdefault.jpg During this episode of Longevity by Design, Dr. Joan Mannick explains how mTOR influences the aging process. She explains that this evolutionarily conserved protein is involved in several cellular functions in the body and acts on longevity-promoting pathways like autophagy. Dr. Mannick also discusses the connection between mTOR and the immune system, sharing her research on how low-dose mTOR inhibitors can upregulate antiviral immunity, creating an opportunity for more targeted vaccines for older adults. After extensive research on mTOR across many species, Dr. Mannick shares impressive insight into how mTOR inhibitors like rapamycin can promote longevity. Tune in to learn more about the latest research in the field. Intro: (00:00-1:20) Dr. Mannick’s background (1:20-6:52) What is mTOR → (6:53–10:15) How Rapamycin acts on mTOR → (10:16–15:17) When to treat with Rapamycin → (15:17–21:36) Dr. Mannick’s trials with rapalogs → (21:37–28:42) The future of Rapamycin → (28:42–31:02) Cautions of anti-aging therapies → (31:02–41:10) Top tip for healthspan → (41:10–41:45) Closing remarks (41:45–end) To learn more: https://hubs.li/Q01CQ86r0 — Let’s Connect! Instagram - https://www.instagram.com/insidetracker Twitter - https://twitter.com/InsideTracker Facebook - https://www.facebook.com/InsideTracker LinkedIn- https://www.linkedin.com/company/insidetracker/  TikTok- https://www.tiktok.com/@insidetracker_  Pinterest- https://www.pinterest.com/insidetracker/  Website - https://www.insidetracker.com/  In the Press - https://www.insidetracker.com/press-page/ https://www.youtube-nocookie.com/embed/879LIpkxlh4 2563 2023-02-22T15:42:07.000Z 2026-10-22T17:43:41.046Z https://longevityharbor.com/en/watch/8B4zMktQqIU Pheraxia podcast: zombie cells, cell delivery and AI in research https://i.ytimg.com/vi/8B4zMktQqIU/hqdefault.jpg In this podcast description, a cell biologist and a Pheraxia representative discuss how a substance reaches its target cell, why senescent cells promote inflammation, and where humans decide between computer and cell studies. https://www.youtube-nocookie.com/embed/8B4zMktQqIU 1092 2026-10-05T07:00:19.000Z 2026-10-22T21:21:22.230Z https://longevityharbor.com/de/watch/8B4zMktQqIU Pheraxia-Podcast: Zombiezellen, Zielzelle und KI in der Forschung https://i.ytimg.com/vi/8B4zMktQqIU/hqdefault.jpg In dieser Podcast-Beschreibung sprechen ein Zellbiologe und ein Pheraxia-Vertreter darüber, wie ein Stoff seine Zielzelle erreicht, warum seneszente Zellen Entzündung fördern und wo Menschen zwischen Rechner- und Zellstudien entscheiden. https://www.youtube-nocookie.com/embed/8B4zMktQqIU 1092 2026-10-05T07:00:19.000Z 2026-10-22T21:21:22.230Z https://longevityharbor.com/en/watch/8Cvibr_sYNE Video description: six daily habits proposed for healthy aging after 55 https://i.ytimg.com/vi/8Cvibr_sYNE/hqdefault.jpg The description says Dr. Cale Smith presents six habits for adults over 55: movement, strength training, anti-inflammatory nutrition, brain health, social connection and better sleep. It links these to mobility, independence and well-being but reports no study results. https://www.youtube-nocookie.com/embed/8Cvibr_sYNE 1476 2026-09-09T22:00:34.000Z 2026-10-22T22:21:20.677Z https://longevityharbor.com/de/watch/8Cvibr_sYNE Videobeschreibung: sechs Alltagsgewohnheiten für gesundes Altern ab 55 https://i.ytimg.com/vi/8Cvibr_sYNE/hqdefault.jpg Laut Beschreibung stellt Dr. Cale Smith sechs Gewohnheiten für Erwachsene über 55 vor: Bewegung, Krafttraining, entzündungshemmende Ernährung, Gehirngesundheit, soziale Verbundenheit und besserer Schlaf. Sie werden mit Mobilität, Selbstständigkeit und Wohlbefinden verknüpft, Studienergebnisse nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/8Cvibr_sYNE 1476 2026-09-09T22:00:34.000Z 2026-10-22T22:21:20.677Z https://longevityharbor.com/en/watch/8DTLGUXxdXI Geriatric and Geroscience-Guided Approaches to Lower Urinary Tract Symptoms and Incontinence https://i.ytimg.com/vi/8DTLGUXxdXI/hqdefault.jpg This presentation lead by George A. Kuchel, MD, FRCP, AGSF at the annual CAIRIBU meeting in 2024. *Collaborating for the Advancement of Interdisciplinary Research in Benign Urology (CAIRIBU) is an umbrella organization that brings together NIDDK-funded investigators devoted exclusively to investigating benign genitourinary diseases and disorders. A primary objective of CAIRIBU is to encourage interdisciplinary interactions and build effective research collaborations that can tackle the most critical questions related to benign prostatic hyperplasia, urolithiasis, bladder disorders, urinary tract infection, pelvic pain, and genitourinary developmental disorders. Visit the CAIRIBU Community here: https://cairibu.urology.wisc.edu/ https://linktr.ee/cairibu https://www.youtube-nocookie.com/embed/8DTLGUXxdXI 3112 2024-12-11T20:44:06.000Z 2026-10-22T18:32:11.694Z https://longevityharbor.com/de/watch/8DTLGUXxdXI Geriatric and Geroscience-Guided Approaches to Lower Urinary Tract Symptoms and Incontinence https://i.ytimg.com/vi/8DTLGUXxdXI/hqdefault.jpg This presentation lead by George A. Kuchel, MD, FRCP, AGSF at the annual CAIRIBU meeting in 2024. *Collaborating for the Advancement of Interdisciplinary Research in Benign Urology (CAIRIBU) is an umbrella organization that brings together NIDDK-funded investigators devoted exclusively to investigating benign genitourinary diseases and disorders. A primary objective of CAIRIBU is to encourage interdisciplinary interactions and build effective research collaborations that can tackle the most critical questions related to benign prostatic hyperplasia, urolithiasis, bladder disorders, urinary tract infection, pelvic pain, and genitourinary developmental disorders. Visit the CAIRIBU Community here: https://cairibu.urology.wisc.edu/ https://linktr.ee/cairibu https://www.youtube-nocookie.com/embed/8DTLGUXxdXI 3112 2024-12-11T20:44:06.000Z 2026-10-22T18:32:11.694Z https://longevityharbor.com/en/watch/8F2gfvTTZZs Longevity Scientist: Fasting, Supplements & Tools for Aging Well w/ Matt Kaeberlein, PhD https://i.ytimg.com/vi/8F2gfvTTZZs/hqdefault.jpg Matt Kaeberlein, PhD dives into how rapamycin and tackling senescent cells could redefine aging, while spotlighting the crucial role of diet, exercise, and sleep. Crush your Workouts and stay hydrated this summer with the Electrolyte + Creatine Combo by MYOXCIENCE: https://bit.ly/electrolyte-stix *Save with code podcast at checkout Connect with Matt @optispan Eat like your life depends it Tee Shirt!: https://bit.ly/3dEHM3e -------------Health and Sleep Tools!----------------------- Berberine Fasting Accelerator: https://amzn.to/3NWv97i Eat like your life depends it Tee Shirt!: https://bit.ly/3dEHM3e Best Sauna Blanket: https://bit.ly/best-sauna-blanket Best High-Protein Snax: http://bit.ly/Carnivore-Crisps Best Mouth Tape (Nexcare): https://amzn.to/31qJayh Get this Metabolic Book: https://amzn.to/3pEfvmZ NeilMed Nasal Wash Kit https://amzn.to/3EUQaY Breath Right Strips: https://amzn.to/31t5VSl A Metabolism Book Should Have: https://amzn.to/2jUiAh5 -----------------------------------------Show Notes-------------------------------------- 0:00 Intro 2:44 Pillars of health: eat, sleep, move, connect. 10:30 Eating protein and exercise can turn up mTOR. 15:20 High dietary protein and resistance training preserves muscle while aging. 19:20 Longevity research is underfunded. 25:10 Obesity was rare 50 years ago. 26:25 Fasting, and time restricting eating may not increase longevity. 30:45 Smoking, sedentary life, alcohol consumption and obesity shorten lifespan. 34:40 Resveratrol is not a longevity drug. 36:45 Spermidine is an autophagy booster. 38:10 Alpha ketoglutarate, urolithin A, and NAD precursors, may increase lifespan. 42:45 Acarbose, SGLT-2 inhibitors, and estrogens can increase lifespan. 44:45 Metformin does not corelate to reduced all-cause mortality. 47:30 NAD is a co-factor required for thousands of metabolic reactions. 52:55 Some epigenetic signatures are predictive of future health outcomes. 54:17 Facial imaging using AI can predict future health outcomes. 58:17 Dunedin Pace measures https://www.youtube-nocookie.com/embed/8F2gfvTTZZs 5376 2024-09-08T15:37:08.000Z 2026-10-22T19:54:18.373Z https://longevityharbor.com/de/watch/8F2gfvTTZZs Longevity Scientist: Fasting, Supplements & Tools for Aging Well w/ Matt Kaeberlein, PhD https://i.ytimg.com/vi/8F2gfvTTZZs/hqdefault.jpg Matt Kaeberlein, PhD dives into how rapamycin and tackling senescent cells could redefine aging, while spotlighting the crucial role of diet, exercise, and sleep. Crush your Workouts and stay hydrated this summer with the Electrolyte + Creatine Combo by MYOXCIENCE: https://bit.ly/electrolyte-stix *Save with code podcast at checkout Connect with Matt @optispan Eat like your life depends it Tee Shirt!: https://bit.ly/3dEHM3e -------------Health and Sleep Tools!----------------------- Berberine Fasting Accelerator: https://amzn.to/3NWv97i Eat like your life depends it Tee Shirt!: https://bit.ly/3dEHM3e Best Sauna Blanket: https://bit.ly/best-sauna-blanket Best High-Protein Snax: http://bit.ly/Carnivore-Crisps Best Mouth Tape (Nexcare): https://amzn.to/31qJayh Get this Metabolic Book: https://amzn.to/3pEfvmZ NeilMed Nasal Wash Kit https://amzn.to/3EUQaY Breath Right Strips: https://amzn.to/31t5VSl A Metabolism Book Should Have: https://amzn.to/2jUiAh5 -----------------------------------------Show Notes-------------------------------------- 0:00 Intro 2:44 Pillars of health: eat, sleep, move, connect. 10:30 Eating protein and exercise can turn up mTOR. 15:20 High dietary protein and resistance training preserves muscle while aging. 19:20 Longevity research is underfunded. 25:10 Obesity was rare 50 years ago. 26:25 Fasting, and time restricting eating may not increase longevity. 30:45 Smoking, sedentary life, alcohol consumption and obesity shorten lifespan. 34:40 Resveratrol is not a longevity drug. 36:45 Spermidine is an autophagy booster. 38:10 Alpha ketoglutarate, urolithin A, and NAD precursors, may increase lifespan. 42:45 Acarbose, SGLT-2 inhibitors, and estrogens can increase lifespan. 44:45 Metformin does not corelate to reduced all-cause mortality. 47:30 NAD is a co-factor required for thousands of metabolic reactions. 52:55 Some epigenetic signatures are predictive of future health outcomes. 54:17 Facial imaging using AI can predict future health outcomes. 58:17 Dunedin Pace measures https://www.youtube-nocookie.com/embed/8F2gfvTTZZs 5376 2024-09-08T15:37:08.000Z 2026-10-22T19:54:18.373Z https://longevityharbor.com/en/watch/8HM5Ho0DnJM Night Owl or Habit? A Sleep Creator's Circadian Rhythm Explainer https://i.ytimg.com/vi/8HM5Ho0DnJM/hqdefault.jpg The description asks whether late nights reflect a natural sleep-wake preference or habits such as scrolling and irregular schedules, and proposes a 7-day self-observation challenge. It attributes this to the creator, not to a reviewed study. https://www.youtube-nocookie.com/embed/8HM5Ho0DnJM 106 2026-10-10T03:37:52.000Z 2026-10-22T20:48:05.038Z https://longevityharbor.com/de/watch/8HM5Ho0DnJM Nachteule oder Gewohnheit? Ein Schlaf-Creator erklärt den circadianen Rhythmus https://i.ytimg.com/vi/8HM5Ho0DnJM/hqdefault.jpg Die Beschreibung fragt, ob späte Nächte eine natürliche Schlaf-Wach-Präferenz oder Gewohnheiten wie Scrollen und unregelmäßige Zeiten widerspiegeln, und schlägt eine 7-Tage-Selbstbeobachtung vor. Dies wird dem Creator zugeschrieben, nicht einer geprüften Studie. https://www.youtube-nocookie.com/embed/8HM5Ho0DnJM 106 2026-10-10T03:37:52.000Z 2026-10-22T20:48:05.038Z https://longevityharbor.com/en/watch/8Ona9PrZjwE Doctor's six longevity rules: description-only overview https://i.ytimg.com/vi/8Ona9PrZjwE/hqdefault.jpg The description says Dr. Ezekiel Emanuel presents six habits from his book that may help lower the risk of dementia, heart disease, cancer and early death. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/8Ona9PrZjwE 3717 2026-07-16T15:06:10.000Z 2026-10-22T23:30:29.653Z https://longevityharbor.com/de/watch/8Ona9PrZjwE Sechs Langlebigkeitsregeln eines Arztes: reine Beschreibungsübersicht https://i.ytimg.com/vi/8Ona9PrZjwE/hqdefault.jpg Laut Beschreibung stellt Dr. Ezekiel Emanuel sechs Gewohnheiten aus seinem Buch vor, die das Risiko für Demenz, Herzkrankheiten, Krebs und frühen Tod senken könnten. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/8Ona9PrZjwE 3717 2026-07-16T15:06:10.000Z 2026-10-22T23:30:29.653Z https://longevityharbor.com/en/watch/8QAtcYMQY38 PEARL Trial: A Blow to Rapamycin’s Healthspan Narrative? https://i.ytimg.com/vi/8QAtcYMQY38/hqdefault.jpg *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]* Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST* 1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender Video of PEARL Trial Researchers: https://youtu.be/dEXBFlQOTf4?si=i6bArV6i6Cfzl5Uo Dr. Kaeberlein's Video: https://youtu.be/JUAXqSSnXzo?si=zAl5-ZxLQVsebDPq Reference [Study 346] Safety and efficacy of rapamycin on healthspan metrics after one year: PEARL Trial Results Girish Harinath, Virginia Lee, Andy Nyquist, Mauricio Moel, Jesper Hagemeier, Stefanie L. Morgan, Anar Isman, Sajad Zalzala medRxiv 2024.08.21.24312372; doi: https://doi.org/10.1101/2024.08.21.24312372 Industry Funding: AgelessRX // Potential Conflicts of Interest: Researchers are employees of Industry ********CRITIQUES, RULES, AND NOTES******** Be aware of the following rules before posting comments: - Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce). Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique: Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached. RULES: If your comment is rude, you will be banned. If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikel https://www.youtube-nocookie.com/embed/8QAtcYMQY38 489 2024-10-14T12:00:14.000Z 2026-10-22T19:32:35.600Z https://longevityharbor.com/de/watch/8QAtcYMQY38 PEARL Trial: A Blow to Rapamycin’s Healthspan Narrative? https://i.ytimg.com/vi/8QAtcYMQY38/hqdefault.jpg *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]* Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST* 1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender Video of PEARL Trial Researchers: https://youtu.be/dEXBFlQOTf4?si=i6bArV6i6Cfzl5Uo Dr. Kaeberlein's Video: https://youtu.be/JUAXqSSnXzo?si=zAl5-ZxLQVsebDPq Reference [Study 346] Safety and efficacy of rapamycin on healthspan metrics after one year: PEARL Trial Results Girish Harinath, Virginia Lee, Andy Nyquist, Mauricio Moel, Jesper Hagemeier, Stefanie L. Morgan, Anar Isman, Sajad Zalzala medRxiv 2024.08.21.24312372; doi: https://doi.org/10.1101/2024.08.21.24312372 Industry Funding: AgelessRX // Potential Conflicts of Interest: Researchers are employees of Industry ********CRITIQUES, RULES, AND NOTES******** Be aware of the following rules before posting comments: - Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce). Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique: Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached. RULES: If your comment is rude, you will be banned. If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikel https://www.youtube-nocookie.com/embed/8QAtcYMQY38 489 2024-10-14T12:00:14.000Z 2026-10-22T19:32:35.600Z https://longevityharbor.com/en/watch/8QlIhxvy9UQ The Only 5 Exercises You Need After 70 to Reverse Aging | Richard Feynman https://i.ytimg.com/vi/8QlIhxvy9UQ/hqdefault.jpg #Aging #Sarcopenia #NeuromuscularSystem 📘 The complete plan to reverse aging with the only 5 exercises after 70: https://health-decoded.netlify.app After 70, your body is not in collapse — it is in a state of imbalance between breakdown and rebuilding, and the signals that drive rebuilding have gone quiet. This video explains the exact biological mechanisms behind muscle loss, bone density decline, and the slowing of motor unit recruitment, and why the right physical inputs can shift that balance back. The five exercises covered here are not arbitrary recommendations. Each one targets a specific mechanism: posterior chain loading for spinal integrity, closed-chain pressing for shoulder stability and core coordination, hip hinging for bone strain at the femur and spine, and single-leg perturbation work for the reactive neuromuscular system that actually prevents falls. What the evidence supports and what most people are never told are two different things. The research on adaptation after 70 is consistent — the tissue still responds, the satellite cells still activate, and the myokine signals released during resistance work reach the brain. The biology does not stop listening. It just needs a louder signal. #Muscle #Strength #Balance #Osteoporosis #Proprioception #BDNF #Metabolism #Fitness #Longevity https://www.youtube-nocookie.com/embed/8QlIhxvy9UQ 2174 2026-09-26T16:00:20.000Z 2026-10-22T17:43:36.955Z https://longevityharbor.com/de/watch/8QlIhxvy9UQ The Only 5 Exercises You Need After 70 to Reverse Aging | Richard Feynman https://i.ytimg.com/vi/8QlIhxvy9UQ/hqdefault.jpg #Aging #Sarcopenia #NeuromuscularSystem 📘 The complete plan to reverse aging with the only 5 exercises after 70: https://health-decoded.netlify.app After 70, your body is not in collapse — it is in a state of imbalance between breakdown and rebuilding, and the signals that drive rebuilding have gone quiet. This video explains the exact biological mechanisms behind muscle loss, bone density decline, and the slowing of motor unit recruitment, and why the right physical inputs can shift that balance back. The five exercises covered here are not arbitrary recommendations. Each one targets a specific mechanism: posterior chain loading for spinal integrity, closed-chain pressing for shoulder stability and core coordination, hip hinging for bone strain at the femur and spine, and single-leg perturbation work for the reactive neuromuscular system that actually prevents falls. What the evidence supports and what most people are never told are two different things. The research on adaptation after 70 is consistent — the tissue still responds, the satellite cells still activate, and the myokine signals released during resistance work reach the brain. The biology does not stop listening. It just needs a louder signal. #Muscle #Strength #Balance #Osteoporosis #Proprioception #BDNF #Metabolism #Fitness #Longevity https://www.youtube-nocookie.com/embed/8QlIhxvy9UQ 2174 2026-09-26T16:00:20.000Z 2026-10-22T17:43:36.955Z https://longevityharbor.com/en/watch/8R89eTygXXg Video description on lifespan trends and proposed longevity therapies https://i.ytimg.com/vi/8R89eTygXXg/hqdefault.jpg The description says global life expectancy rose from 31 years in 1900 to over 73 today, with Japan, Singapore, Switzerland and South Korea above 85. It attributes this to science and lists emerging therapies, but gives no trial results. https://www.youtube-nocookie.com/embed/8R89eTygXXg 464 2025-12-01T13:30:12.000Z 2026-10-23T03:23:00.687Z https://longevityharbor.com/de/watch/8R89eTygXXg Videobeschreibung zu Lebensspannen-Trends und vorgeschlagenen Longevity-Therapien https://i.ytimg.com/vi/8R89eTygXXg/hqdefault.jpg Laut Beschreibung stieg die globale Lebenserwartung von 31 Jahren 1900 auf heute über 73; Japan, Singapur, die Schweiz und Südkorea liegen über 85. Sie schreibt dies der Wissenschaft zu und nennt neue Therapien, ohne Studienergebnisse zu liefern. https://www.youtube-nocookie.com/embed/8R89eTygXXg 464 2025-12-01T13:30:12.000Z 2026-10-23T03:23:00.687Z https://longevityharbor.com/en/watch/8YDFmJ2CFMA Epigenetik: Der unterschätzte Hebel für gesundes Altern. #202 Mit Dr. Manuel Burzler https://i.ytimg.com/vi/8YDFmJ2CFMA/hqdefault.jpg Sind unsere Gene wirklich unser Schicksal - oder können wir beeinflussen, welche Prozesse in unserem Körper aktiv sind? 🧬✨ In dieser spannenden Episode von HEALTHWISE spricht Host Elisabeth Seidel mit Dr. Manuel Burzler über Epigenetik, Zellgesundheit und die Frage, wie unser Lebensstil unsere Biologie mitprägen kann. Denn Epigenetik zeigt: Unsere Gene sind zwar die Grundlage, aber sie funktionieren nicht wie ein festgeschriebener Bauplan. Vielmehr können Faktoren wie Schlaf, Ernährung, Stress, Bewegung, Licht, Mikronährstoffe und Umweltreize mitbestimmen, welche Gene „an“ oder „aus“ geschaltet werden. Dr. Manuel Burzler erklärt Epigenetik mit einer einfachen Metapher: Unsere Gene sind wie die Tasten eines Klaviers - die Epigenetik ist der Spieler, der entscheidet, welche Melodie entsteht. Und genau hier beginnt die spannende Frage: Welche Alltagsfaktoren beeinflussen diesen inneren „Klavierspieler“? In der Folge geht es unter anderem darum, warum Schlaf laut Dr. Burzler einer der wichtigsten Hebel für Regeneration und Gesundheit ist, wie chronischer Stress unsere biochemischen Prozesse beeinflussen kann und weshalb Ernährung viel mehr ist als Kalorien, Proteine, Fette und Kohlenhydrate. Besonders spannend: Dr. Burzler spricht darüber, wie sekundäre Pflanzenstoffe, Ballaststoffe, Mitochondrien, Methylierung und Mikronährstoffe mit unserer Zellgesundheit zusammenhängen können. Was dich in dieser Folge erwartet: 🧬 Epigenetik einfach erklärt - Warum deine Gene nicht dein festes Schicksal sind und was es bedeutet, Gene „an“ oder „aus“ zu schalten. 🎹 Die Klavier-Metapher - Wie Dr. Burzler verständlich erklärt, was Gene und Epigenetik miteinander zu tun haben. 💤 Schlaf als Nummer 1 - Warum Schlaf für Regeneration, Gehirn, Stoffwechsel und Zellgesundheit so zentral ist. 🔥 Stress & Methylierung - Wie Stresshormone, Methylgruppen, B-Vitamine, Magnesium und Aminosäuren miteinander verbunden sein können. 🌱 Ernährung als Information - Warum Lebensmittel nicht nur Energie liefern, sondern auch Signale für unseren Kö https://www.youtube-nocookie.com/embed/8YDFmJ2CFMA 3240 2026-06-10T03:00:38.000Z 2026-10-22T17:11:30.664Z https://longevityharbor.com/de/watch/8YDFmJ2CFMA Epigenetik: Der unterschätzte Hebel für gesundes Altern. #202 Mit Dr. Manuel Burzler https://i.ytimg.com/vi/8YDFmJ2CFMA/hqdefault.jpg Sind unsere Gene wirklich unser Schicksal - oder können wir beeinflussen, welche Prozesse in unserem Körper aktiv sind? 🧬✨ In dieser spannenden Episode von HEALTHWISE spricht Host Elisabeth Seidel mit Dr. Manuel Burzler über Epigenetik, Zellgesundheit und die Frage, wie unser Lebensstil unsere Biologie mitprägen kann. Denn Epigenetik zeigt: Unsere Gene sind zwar die Grundlage, aber sie funktionieren nicht wie ein festgeschriebener Bauplan. Vielmehr können Faktoren wie Schlaf, Ernährung, Stress, Bewegung, Licht, Mikronährstoffe und Umweltreize mitbestimmen, welche Gene „an“ oder „aus“ geschaltet werden. Dr. Manuel Burzler erklärt Epigenetik mit einer einfachen Metapher: Unsere Gene sind wie die Tasten eines Klaviers - die Epigenetik ist der Spieler, der entscheidet, welche Melodie entsteht. Und genau hier beginnt die spannende Frage: Welche Alltagsfaktoren beeinflussen diesen inneren „Klavierspieler“? In der Folge geht es unter anderem darum, warum Schlaf laut Dr. Burzler einer der wichtigsten Hebel für Regeneration und Gesundheit ist, wie chronischer Stress unsere biochemischen Prozesse beeinflussen kann und weshalb Ernährung viel mehr ist als Kalorien, Proteine, Fette und Kohlenhydrate. Besonders spannend: Dr. Burzler spricht darüber, wie sekundäre Pflanzenstoffe, Ballaststoffe, Mitochondrien, Methylierung und Mikronährstoffe mit unserer Zellgesundheit zusammenhängen können. Was dich in dieser Folge erwartet: 🧬 Epigenetik einfach erklärt - Warum deine Gene nicht dein festes Schicksal sind und was es bedeutet, Gene „an“ oder „aus“ zu schalten. 🎹 Die Klavier-Metapher - Wie Dr. Burzler verständlich erklärt, was Gene und Epigenetik miteinander zu tun haben. 💤 Schlaf als Nummer 1 - Warum Schlaf für Regeneration, Gehirn, Stoffwechsel und Zellgesundheit so zentral ist. 🔥 Stress & Methylierung - Wie Stresshormone, Methylgruppen, B-Vitamine, Magnesium und Aminosäuren miteinander verbunden sein können. 🌱 Ernährung als Information - Warum Lebensmittel nicht nur Energie liefern, sondern auch Signale für unseren Kö https://www.youtube-nocookie.com/embed/8YDFmJ2CFMA 3240 2026-06-10T03:00:38.000Z 2026-10-22T17:11:30.664Z https://longevityharbor.com/en/watch/8ctnmcMHI-4 PEPMED 2026 talk summary: circadian and seasonal optimization for longevity https://i.ytimg.com/vi/8ctnmcMHI-4/hqdefault.jpg A Youthful Medicine post describes Dr. Elizabeth F. Yurth's PEPMED 2026 talk on seasonal and circadian optimization, arguing longevity care should consider the whole person, not just added medications, supplements, hormones or peptides. https://www.youtube-nocookie.com/embed/8ctnmcMHI-4 107 2026-09-21T16:37:35.000Z 2026-10-22T22:02:38.243Z https://longevityharbor.com/de/watch/8ctnmcMHI-4 PEPMED-2026-Vortrag: zirkadiane und saisonale Optimierung für Langlebigkeit https://i.ytimg.com/vi/8ctnmcMHI-4/hqdefault.jpg Ein Beitrag von Youthful Medicine beschreibt den PEPMED-2026-Vortrag von Dr. Elizabeth F. Yurth zur saisonalen und zirkadianen Optimierung und plädiert dafür, Langlebigkeitsmedizin am ganzen Menschen auszurichten statt nur weitere Medikamente, Nahrungsergänzungsmittel, Hormone oder Peptide hinzuzufügen. https://www.youtube-nocookie.com/embed/8ctnmcMHI-4 107 2026-09-21T16:37:35.000Z 2026-10-22T22:02:38.243Z https://longevityharbor.com/en/watch/8mesFW7JGgY Healthy Aging: What Sleep Really Does to Your Aging Brain | Longevity Science https://i.ytimg.com/vi/8mesFW7JGgY/hqdefault.jpg Sleep does more than make you feel rested. It is part of the biology that supports memory, attention, learning, mood, and everyday function. In this episode of The Longevity Code, we explore what sleep really does to an aging brain — and why sleep and healthy aging belong in the same conversation. As we get older, sleep can change. People may fall asleep earlier, wake earlier, experience lighter sleep, or wake more often during the night. Older adults generally still need about 7–9 hours of sleep, while both REM and non-REM sleep are involved in memory processes. In this healthy aging documentary, we explore: • How sleep changes with age • What happens in the brain during sleep • Why REM and non-REM sleep matter • Sleep, memory, attention, and brain function • Circadian rhythm and changing sleep timing • Sleep quality versus sleep duration • Common factors that can disrupt sleep • Practical habits that support healthy sleep • Why persistent sleep problems should not simply be dismissed as normal aging CHAPTERS / TIMESTAMPS 00:00 Hook — Your Brain Never Truly Switches Off 00:16 What Sleep Does During the Night 01:52 Sleep and Memory 03:04 Healthy Aging and Brain Function 03:28 How Sleep Changes With Age 05:12 How Researchers Measure Sleep 06:16 Why Sleep Quality Matters 08:48 Circadian Rhythm and Healthy Aging 10:48 Sleep as Part of a Healthy Aging System 12:00 Sleep, Cognition, and Daily Function 13:20 Sleep Duration: How Much Is Enough? 15:04 Common Sleep Disruptors 17:12 Practical Habits for Better Sleep 19:04 What Sleep Really Means for Healthy Aging 19:36 Final Takeaway 19:44 Conclusion & Subscribe The goal is not to promise that sleep can stop aging. The goal is to understand how sleep fits into the larger system of healthy aging, brain health, recovery, and longevity. If you are interested in healthy aging after 40, healthy aging after 50, brain health, sleep quality, longevity science, and the science of aging, this episode provides an evidence-aware overview of how sleep fits into the bigger picture https://www.youtube-nocookie.com/embed/8mesFW7JGgY 1201 2026-09-18T13:00:10.000Z 2026-10-22T19:21:25.124Z https://longevityharbor.com/de/watch/8mesFW7JGgY Healthy Aging: What Sleep Really Does to Your Aging Brain | Longevity Science https://i.ytimg.com/vi/8mesFW7JGgY/hqdefault.jpg Sleep does more than make you feel rested. It is part of the biology that supports memory, attention, learning, mood, and everyday function. In this episode of The Longevity Code, we explore what sleep really does to an aging brain — and why sleep and healthy aging belong in the same conversation. As we get older, sleep can change. People may fall asleep earlier, wake earlier, experience lighter sleep, or wake more often during the night. Older adults generally still need about 7–9 hours of sleep, while both REM and non-REM sleep are involved in memory processes. In this healthy aging documentary, we explore: • How sleep changes with age • What happens in the brain during sleep • Why REM and non-REM sleep matter • Sleep, memory, attention, and brain function • Circadian rhythm and changing sleep timing • Sleep quality versus sleep duration • Common factors that can disrupt sleep • Practical habits that support healthy sleep • Why persistent sleep problems should not simply be dismissed as normal aging CHAPTERS / TIMESTAMPS 00:00 Hook — Your Brain Never Truly Switches Off 00:16 What Sleep Does During the Night 01:52 Sleep and Memory 03:04 Healthy Aging and Brain Function 03:28 How Sleep Changes With Age 05:12 How Researchers Measure Sleep 06:16 Why Sleep Quality Matters 08:48 Circadian Rhythm and Healthy Aging 10:48 Sleep as Part of a Healthy Aging System 12:00 Sleep, Cognition, and Daily Function 13:20 Sleep Duration: How Much Is Enough? 15:04 Common Sleep Disruptors 17:12 Practical Habits for Better Sleep 19:04 What Sleep Really Means for Healthy Aging 19:36 Final Takeaway 19:44 Conclusion & Subscribe The goal is not to promise that sleep can stop aging. The goal is to understand how sleep fits into the larger system of healthy aging, brain health, recovery, and longevity. If you are interested in healthy aging after 40, healthy aging after 50, brain health, sleep quality, longevity science, and the science of aging, this episode provides an evidence-aware overview of how sleep fits into the bigger picture https://www.youtube-nocookie.com/embed/8mesFW7JGgY 1201 2026-09-18T13:00:10.000Z 2026-10-22T19:21:25.124Z https://longevityharbor.com/en/watch/8mlRkXZFvi8 The Truth About Biological Age Tests https://i.ytimg.com/vi/8mlRkXZFvi8/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Matt Kaeberlein dives into the controversial world of biological age tests. Many direct-to-consumer tests claim to measure your biological age, but are they accurate or useful? Based on extensive research and clinical experience, we uncover why these tests are statistically meaningless, lack regulatory validation, and fail to provide actionable health insights. Instead, we highlight proven biomarkers that actually contribute to longevity and well-being. If you're considering spending money on a biological age test, watch this first!In this episode of the Optisan Podcast, we dive into the controversial world of biological age tests. Many direct-to-consumer tests claim to measure your biological age, but are they accurate or useful? Based on extensive research and clinical experience, we uncover why these tests are statistically meaningless, lack regulatory validation, and fail to provide actionable health insights. Instead, we highlight proven biomarkers that actually contribute to longevity and well-being. If you're considering spending money on a biological age test, watch this first! 0:00 - Introduction & Overview 1:09 - Why Biological Age Tests Are Misleading 2:26 - Optisan’s Research on Biological Age Tests 4:40 - Understanding Biological Age Clocks & Their Limitations 6:34 - The Four Major Problems with These Tests 7:57 - Lack of Regulatory Approval & Oversight 10:28 - Are Doctors Benefiting from These Tests? 12:22 - Reliable Biomarkers for Longevity & Health Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment https://www.youtube-nocookie.com/embed/8mlRkXZFvi8 874 2025-03-11T14:00:10.000Z 2026-10-22T19:04:38.855Z https://longevityharbor.com/de/watch/8mlRkXZFvi8 The Truth About Biological Age Tests https://i.ytimg.com/vi/8mlRkXZFvi8/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Matt Kaeberlein dives into the controversial world of biological age tests. Many direct-to-consumer tests claim to measure your biological age, but are they accurate or useful? Based on extensive research and clinical experience, we uncover why these tests are statistically meaningless, lack regulatory validation, and fail to provide actionable health insights. Instead, we highlight proven biomarkers that actually contribute to longevity and well-being. If you're considering spending money on a biological age test, watch this first!In this episode of the Optisan Podcast, we dive into the controversial world of biological age tests. Many direct-to-consumer tests claim to measure your biological age, but are they accurate or useful? Based on extensive research and clinical experience, we uncover why these tests are statistically meaningless, lack regulatory validation, and fail to provide actionable health insights. Instead, we highlight proven biomarkers that actually contribute to longevity and well-being. If you're considering spending money on a biological age test, watch this first! 0:00 - Introduction & Overview 1:09 - Why Biological Age Tests Are Misleading 2:26 - Optisan’s Research on Biological Age Tests 4:40 - Understanding Biological Age Clocks & Their Limitations 6:34 - The Four Major Problems with These Tests 7:57 - Lack of Regulatory Approval & Oversight 10:28 - Are Doctors Benefiting from These Tests? 12:22 - Reliable Biomarkers for Longevity & Health Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment https://www.youtube-nocookie.com/embed/8mlRkXZFvi8 874 2025-03-11T14:00:10.000Z 2026-10-22T19:04:38.855Z https://longevityharbor.com/en/watch/8oMuIaoASg0 How Much Protein Should You Eat? #davidsinclair #peterattia #protein https://i.ytimg.com/vi/8oMuIaoASg0/hqdefault.jpg @interoai Does dietary protein help you live longer, or is it aging you faster? Two opposing camps have formed in the longevity community. The anti-protein camp is best represented by Harvard longevity scientist, David Sinclair. He advocates a mostly plant-based, low-protein diet based on research showing that high protein increases mTOR activation, accelerating the best known mechanism of aging. Dr. David Sinclair: “…mTOR…target of rapamycin, so MTOR is a longevity gene that makes a protein that senses amino acids. So, when you eat a big steak, mTOR activity actually is activated. And mTOR now says…ok, I’ve got lots of protein, I’m going to make muscle. I’m gonna burn energy, and that’s why when you eat a steak, you actually build up muscle more than if you don’t eat a lot of protein.” Drugs inhibiting mTOR, on the other hand, like rapamycin have proven to extend mouse lifespans by up to 20%. In the high-protein camp, we have Dr. Peter Attia, who argues that a more athletic physique, built on an omnivorous, high-protein diet makes us more robust to injury and disease, making additional mTOR activation irrelevant. It’s worth noting, somewhat ironically though, that Dr. Attia is a major proponent of rapamycin as an anti-aging therapy, while Dr. Sinclair is not. Dr. Peter Attia: “I don’t find the data for people below 50 having an increase in mortality with high protein being at all convincing. I think that is easily attributed to caloric excess as opposed to protein excess. It’s very important when people are still able to put on muscle, that they put on as much as possible. Once you’re in the over 50 category, you’re kind of clawing on for dear life, and trying to keep as much of that muscle as possible. So, I don’t really want people entering middle age with a muscle deficit.” https://www.youtube-nocookie.com/embed/8oMuIaoASg0 108 2025-01-30T17:27:26.000Z 2026-10-22T19:54:21.269Z https://longevityharbor.com/de/watch/8oMuIaoASg0 How Much Protein Should You Eat? #davidsinclair #peterattia #protein https://i.ytimg.com/vi/8oMuIaoASg0/hqdefault.jpg @interoai Does dietary protein help you live longer, or is it aging you faster? Two opposing camps have formed in the longevity community. The anti-protein camp is best represented by Harvard longevity scientist, David Sinclair. He advocates a mostly plant-based, low-protein diet based on research showing that high protein increases mTOR activation, accelerating the best known mechanism of aging. Dr. David Sinclair: “…mTOR…target of rapamycin, so MTOR is a longevity gene that makes a protein that senses amino acids. So, when you eat a big steak, mTOR activity actually is activated. And mTOR now says…ok, I’ve got lots of protein, I’m going to make muscle. I’m gonna burn energy, and that’s why when you eat a steak, you actually build up muscle more than if you don’t eat a lot of protein.” Drugs inhibiting mTOR, on the other hand, like rapamycin have proven to extend mouse lifespans by up to 20%. In the high-protein camp, we have Dr. Peter Attia, who argues that a more athletic physique, built on an omnivorous, high-protein diet makes us more robust to injury and disease, making additional mTOR activation irrelevant. It’s worth noting, somewhat ironically though, that Dr. Attia is a major proponent of rapamycin as an anti-aging therapy, while Dr. Sinclair is not. Dr. Peter Attia: “I don’t find the data for people below 50 having an increase in mortality with high protein being at all convincing. I think that is easily attributed to caloric excess as opposed to protein excess. It’s very important when people are still able to put on muscle, that they put on as much as possible. Once you’re in the over 50 category, you’re kind of clawing on for dear life, and trying to keep as much of that muscle as possible. So, I don’t really want people entering middle age with a muscle deficit.” https://www.youtube-nocookie.com/embed/8oMuIaoASg0 108 2025-01-30T17:27:26.000Z 2026-10-22T19:54:21.269Z https://longevityharbor.com/en/watch/8uqgVK21VGQ Podcast description: intermittent fasting, timing and study context https://i.ytimg.com/vi/8uqgVK21VGQ/hqdefault.jpg The description says Mark and Linnea discuss intermittent fasting, when to place the eating window, and what current studies on fasting, sport, women and longevity show. https://www.youtube-nocookie.com/embed/8uqgVK21VGQ 4802 2026-08-18T07:26:15.000Z 2026-10-22T22:56:45.555Z https://longevityharbor.com/de/watch/8uqgVK21VGQ Podcast-Beschreibung: Intervallfasten, Timing und Studienlage https://i.ytimg.com/vi/8uqgVK21VGQ/hqdefault.jpg Laut Beschreibung sprechen Mark und Linnea über Intervallfasten, die Lage des Essensfensters und die aktuelle Studienlage zu Fasten, Sport, Frauen und Langlebigkeit. https://www.youtube-nocookie.com/embed/8uqgVK21VGQ 4802 2026-08-18T07:26:15.000Z 2026-10-22T22:56:45.555Z https://longevityharbor.com/en/watch/8vUWaZLwqVE Is Rapamycin the Best Longevity Drug? with Dr Rick Cohen https://i.ytimg.com/vi/8vUWaZLwqVE/hqdefault.jpg Dive into the fascinating world of longevity research as we explore rapamycin, potentially the most powerful anti-aging pharmaceutical currently known. Dr. Rick Cohen, longevity physician with over 25 years of experience, reveals how this natural molecule discovered on Easter Island targets a fundamental cellular pathway called mTOR that acts as our body's metabolic switch between growth and repair. The conversation uncovers the remarkable story behind rapamycin's discovery - how it sat forgotten in a researcher's freezer for years before its life-extending properties were recognized. Dr. Rick explains that mTOR has been conserved through billions of years of evolution precisely because it's so critical to survival, sensing nutrient availability and telling cells whether to grow or repair themselves. What makes this discussion particularly valuable is Dr. Rick's practical approach to using rapamycin as a metabolic health tool rather than a miracle drug. He shares insights on proper dosing strategies, emphasizing the importance of cycling between periods of mTOR suppression and activation to mimic natural patterns our bodies evolved with. This cycling approach - perhaps taking rapamycin for a few months, then taking a month off for anabolic growth through strength training - may be key to optimizing its benefits. The breadth of rapamycin's benefits is truly remarkable - from hair regrowth and skin rejuvenation to improvements in hearing, fertility, and protection against diseases ranging from Alzheimer's to atherosclerosis. This suggests rapamycin isn't just treating symptoms but addressing a fundamental mechanism of aging itself. Ready to understand how this single pathway could influence every aspect of how we age? Listen now to discover why balancing growth and repair cycles might be the key to extending your healthspan and potentially your healthspan and potentially your lifespan. Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/ Get your scan https://innerscopic. https://www.youtube-nocookie.com/embed/8vUWaZLwqVE 2521 2025-08-07T07:02:16.000Z 2026-10-22T19:32:36.472Z https://longevityharbor.com/de/watch/8vUWaZLwqVE Is Rapamycin the Best Longevity Drug? with Dr Rick Cohen https://i.ytimg.com/vi/8vUWaZLwqVE/hqdefault.jpg Dive into the fascinating world of longevity research as we explore rapamycin, potentially the most powerful anti-aging pharmaceutical currently known. Dr. Rick Cohen, longevity physician with over 25 years of experience, reveals how this natural molecule discovered on Easter Island targets a fundamental cellular pathway called mTOR that acts as our body's metabolic switch between growth and repair. The conversation uncovers the remarkable story behind rapamycin's discovery - how it sat forgotten in a researcher's freezer for years before its life-extending properties were recognized. Dr. Rick explains that mTOR has been conserved through billions of years of evolution precisely because it's so critical to survival, sensing nutrient availability and telling cells whether to grow or repair themselves. What makes this discussion particularly valuable is Dr. Rick's practical approach to using rapamycin as a metabolic health tool rather than a miracle drug. He shares insights on proper dosing strategies, emphasizing the importance of cycling between periods of mTOR suppression and activation to mimic natural patterns our bodies evolved with. This cycling approach - perhaps taking rapamycin for a few months, then taking a month off for anabolic growth through strength training - may be key to optimizing its benefits. The breadth of rapamycin's benefits is truly remarkable - from hair regrowth and skin rejuvenation to improvements in hearing, fertility, and protection against diseases ranging from Alzheimer's to atherosclerosis. This suggests rapamycin isn't just treating symptoms but addressing a fundamental mechanism of aging itself. Ready to understand how this single pathway could influence every aspect of how we age? Listen now to discover why balancing growth and repair cycles might be the key to extending your healthspan and potentially your healthspan and potentially your lifespan. Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/ Get your scan https://innerscopic. https://www.youtube-nocookie.com/embed/8vUWaZLwqVE 2521 2025-08-07T07:02:16.000Z 2026-10-22T19:32:36.472Z https://longevityharbor.com/en/watch/92AZj0bfWyU Intervallfasten: Diese 5 Tipps steigern die Effektivität der Autophagie https://i.ytimg.com/vi/92AZj0bfWyU/hqdefault.jpg Online-Workshop mit Dr. med. Ulrich Bauhofer: Erfahren Sie, wie Sie die vergessenen Selbstheilungskräfte Ihres Körpers reaktivieren – ganzheitlich, wissenschaftlich fundiert und kostenfrei. ▶︎ https://www.holistic.house/online-workshop Machen Sie den Test und entdecken Sie, welche Ernährung und Routinen optimal zu Ihrem Körpertyp passen! 💡 Erhalten Sie Ihren individuellen Gesundheitsplan für mehr Energie, Vitalität und Wohlbefinden: ▶︎ https://www.holistic.house/koerpertypen-test?utm_source=youtube.com&utm_medium=social&utm_campaign=evergreen Autophagie: Darunter versteht man unser körpereigenes Reinigungs- und Recyclingsystem. Heute wollen wir den Schwerpunkt auf Tricks legen, die die Autophagie intensivieren, erleichtern und alltagstauglicher machen. Ich wünsche Ihnen viel Spaß, Ihr Dr. med. Ulrich Bauhofer Erwähnte Videos: Diese Gewohnheiten garantieren ein langes Leben! Autophagie ▶︎https://youtu.be/HZx1wGgwdm4 Intervallfasten: Diese 10 kritischen FEHLER musst du kennen ▶︎https://youtu.be/ujlOKghHSn8 Erwähnte Studien: Intervallfasten ▶︎https://www.dge.de/gesunde-ernaehrung/diaeten-und-fasten/intervallfasten/ _____________________________________________________________ 📕 Ihre Gesundheitsreise beginnt hier: ▶︎ Finden Sie Ihren Körpertyp heraus: https://holistic.house/koerpertypen-test-yt ▶︎ Ihr Detox-Programm für Zuhause: https://www.holistic.house/reset-yt ▶︎ Der 21-Tage-Kickstart Abnehmkurs: https://holistic.house/21tage-kickstart-yt ▶︎ Online-Workshop mit Dr. med. Ulrich Bauhofer: https://www.holistic.house/online-workshop-yt _____________________________________________________________ ▶︎ Hier erfahren Sie mehr: https://www.holistic.house/ ▶︎ Mein Tiktok: https://www.tiktok.com/@dr.med.ulrich.bauhofer ▶︎ Mein Instagram: https://www.instagram.com/ulrichbauhofer/ ▶︎ Mein LinkedIn: https://www.linkedin.com/in/dr-med-ulrich-bauhofer ▶︎ Was möchten Sie in Zukunft auf diesem Kanal sehen? Ihre Meinung zählt: https://www.holistic.house/umfrage Dr. med. Ulrich Bauhofer war 1980 einer der ersten beide https://www.youtube-nocookie.com/embed/92AZj0bfWyU 848 2023-09-17T08:00:05.000Z 2026-10-22T19:32:41.947Z https://longevityharbor.com/de/watch/92AZj0bfWyU Intervallfasten: Diese 5 Tipps steigern die Effektivität der Autophagie https://i.ytimg.com/vi/92AZj0bfWyU/hqdefault.jpg Online-Workshop mit Dr. med. Ulrich Bauhofer: Erfahren Sie, wie Sie die vergessenen Selbstheilungskräfte Ihres Körpers reaktivieren – ganzheitlich, wissenschaftlich fundiert und kostenfrei. ▶︎ https://www.holistic.house/online-workshop Machen Sie den Test und entdecken Sie, welche Ernährung und Routinen optimal zu Ihrem Körpertyp passen! 💡 Erhalten Sie Ihren individuellen Gesundheitsplan für mehr Energie, Vitalität und Wohlbefinden: ▶︎ https://www.holistic.house/koerpertypen-test?utm_source=youtube.com&utm_medium=social&utm_campaign=evergreen Autophagie: Darunter versteht man unser körpereigenes Reinigungs- und Recyclingsystem. Heute wollen wir den Schwerpunkt auf Tricks legen, die die Autophagie intensivieren, erleichtern und alltagstauglicher machen. Ich wünsche Ihnen viel Spaß, Ihr Dr. med. Ulrich Bauhofer Erwähnte Videos: Diese Gewohnheiten garantieren ein langes Leben! Autophagie ▶︎https://youtu.be/HZx1wGgwdm4 Intervallfasten: Diese 10 kritischen FEHLER musst du kennen ▶︎https://youtu.be/ujlOKghHSn8 Erwähnte Studien: Intervallfasten ▶︎https://www.dge.de/gesunde-ernaehrung/diaeten-und-fasten/intervallfasten/ _____________________________________________________________ 📕 Ihre Gesundheitsreise beginnt hier: ▶︎ Finden Sie Ihren Körpertyp heraus: https://holistic.house/koerpertypen-test-yt ▶︎ Ihr Detox-Programm für Zuhause: https://www.holistic.house/reset-yt ▶︎ Der 21-Tage-Kickstart Abnehmkurs: https://holistic.house/21tage-kickstart-yt ▶︎ Online-Workshop mit Dr. med. Ulrich Bauhofer: https://www.holistic.house/online-workshop-yt _____________________________________________________________ ▶︎ Hier erfahren Sie mehr: https://www.holistic.house/ ▶︎ Mein Tiktok: https://www.tiktok.com/@dr.med.ulrich.bauhofer ▶︎ Mein Instagram: https://www.instagram.com/ulrichbauhofer/ ▶︎ Mein LinkedIn: https://www.linkedin.com/in/dr-med-ulrich-bauhofer ▶︎ Was möchten Sie in Zukunft auf diesem Kanal sehen? Ihre Meinung zählt: https://www.holistic.house/umfrage Dr. med. Ulrich Bauhofer war 1980 einer der ersten beide https://www.youtube-nocookie.com/embed/92AZj0bfWyU 848 2023-09-17T08:00:05.000Z 2026-10-22T19:32:41.947Z https://longevityharbor.com/en/watch/92B3h3BuB-4 Video description explains cellular senescence, p53, telomeres and SASP https://i.ytimg.com/vi/92B3h3BuB-4/hqdefault.jpg According to the description, the video explains why cells stop dividing and covers cellular senescence, including p53, telomere shortening, the DNA damage response and the senescence-associated secretory phenotype, plus roles in aging and diseases such as cancer and Alzheimer's. https://www.youtube-nocookie.com/embed/92B3h3BuB-4 456 2026-03-21T18:07:19.000Z 2026-10-23T01:59:17.058Z https://longevityharbor.com/de/watch/92B3h3BuB-4 Videobeschreibung erklärt zelluläre Seneszenz, p53, Telomere und SASP https://i.ytimg.com/vi/92B3h3BuB-4/hqdefault.jpg Laut Beschreibung erklärt das Video, warum Zellen aufhören zu teilen, und behandelt zelluläre Seneszenz mit p53, Telomerverkürzung, der DNA-Schadensantwort und dem seneszenzassoziierten sekretorischen Phänotyp sowie Rollen bei Altern und Krankheiten wie Krebs und Alzheimer. https://www.youtube-nocookie.com/embed/92B3h3BuB-4 456 2026-03-21T18:07:19.000Z 2026-10-23T01:59:17.058Z https://longevityharbor.com/en/watch/94whSqsypT0 Aging Clocks as Systemic Markers of Longevity - Prof Jan Gruber at Longevity & Crypto Day Abu Dhabi https://i.ytimg.com/vi/94whSqsypT0/hqdefault.jpg Aging Clocks as Systemic Markers of Longevity - Prof Jan Gruber at Longevity & Crypto Day Abu Dhabi https://www.youtube-nocookie.com/embed/94whSqsypT0 986 2023-10-31T16:00:06.000Z 2026-10-22T19:21:27.694Z https://longevityharbor.com/de/watch/94whSqsypT0 Aging Clocks as Systemic Markers of Longevity - Prof Jan Gruber at Longevity & Crypto Day Abu Dhabi https://i.ytimg.com/vi/94whSqsypT0/hqdefault.jpg Aging Clocks as Systemic Markers of Longevity - Prof Jan Gruber at Longevity & Crypto Day Abu Dhabi https://www.youtube-nocookie.com/embed/94whSqsypT0 986 2023-10-31T16:00:06.000Z 2026-10-22T19:21:27.694Z https://longevityharbor.com/en/watch/95ISQC6YS3Q Rapamycin at low doses and anti-aging signals in WRL-68 cells https://i.ytimg.com/vi/95ISQC6YS3Q/hqdefault.jpg The description reports a cell study in which low doses of rapamycin triggered anti-aging effects by improving mitochondrial health and density and reducing oxidative damage, unlike toxic high doses. This is laboratory cell work, not evidence of benefit in human lifespan. https://www.youtube-nocookie.com/embed/95ISQC6YS3Q 361 2026-04-06T07:26:20.000Z 2026-10-23T01:40:47.253Z https://longevityharbor.com/de/watch/95ISQC6YS3Q Rapamycin in niedrigen Dosen und Anti-Aging-Signale in WRL-68-Zellen https://i.ytimg.com/vi/95ISQC6YS3Q/hqdefault.jpg Die Beschreibung berichtet von einer Zellstudie, in der niedrige Rapamycin-Dosen Anti-Aging-Effekte auslösten, indem sie die Gesundheit und Dichte der Mitochondrien verbesserten und oxidativen Schaden verringerten, anders als toxische hohe Dosen. Dies ist Laborarbeit an Zellen, kein Beleg für einen Nutzen für die menschliche Lebensspanne. https://www.youtube-nocookie.com/embed/95ISQC6YS3Q 361 2026-04-06T07:26:20.000Z 2026-10-23T01:40:47.253Z https://longevityharbor.com/en/watch/98nB_ZH846I Blue light at midnight and the body clock: two cited light studies https://i.ytimg.com/vi/98nB_ZH846I/hqdefault.jpg The description says a bright screen at midnight may shift circadian phase, delaying the melatonin signal; it cites a 2001 light study and a 2005 e-reader experiment. https://www.youtube-nocookie.com/embed/98nB_ZH846I 96 2026-09-14T13:00:35.000Z 2026-10-22T22:12:38.394Z https://longevityharbor.com/de/watch/98nB_ZH846I Blaulicht um Mitternacht und die innere Uhr: zwei zitierte Lichtstudien https://i.ytimg.com/vi/98nB_ZH846I/hqdefault.jpg Laut Beschreibung kann ein heller Bildschirm um Mitternacht die circadiane Phase verschieben und das Melatoninsignal verzögern; genannt werden eine Lichtstudie von 2001 und ein E-Reader-Experiment von 2005. https://www.youtube-nocookie.com/embed/98nB_ZH846I 96 2026-09-14T13:00:35.000Z 2026-10-22T22:12:38.394Z https://longevityharbor.com/en/watch/9GBT9RfNk6k Podcast description: sleep apnea, circadian rhythms and cognitive health https://i.ytimg.com/vi/9GBT9RfNk6k/hqdefault.jpg The description says host Deborah Westfall talks with sleep and pulmonary physician Dr. Paul Chung about sleep deprivation, sleep apnea and disrupted circadian rhythms, and about his research on sleep and rest/activity rhythms in adults with Down syndrome as possible early markers of cognitive decline. https://www.youtube-nocookie.com/embed/9GBT9RfNk6k 3153 2026-06-03T11:00:02.000Z 2026-10-23T00:07:31.124Z https://longevityharbor.com/de/watch/9GBT9RfNk6k Podcast-Beschreibung: Schlafapnoe, circadiane Rhythmen und kognitive Gesundheit https://i.ytimg.com/vi/9GBT9RfNk6k/hqdefault.jpg Laut Beschreibung spricht Gastgeberin Deborah Westfall mit dem Schlaf- und Lungenfacharzt Dr. Paul Chung über Schlafmangel, Schlafapnoe und gestörte circadiane Rhythmen sowie über seine Forschung zu Schlaf- und Ruhe-/Aktivitätsrhythmen bei Erwachsenen mit Down-Syndrom als mögliche frühe Marker kognitiven Abbaus. https://www.youtube-nocookie.com/embed/9GBT9RfNk6k 3153 2026-06-03T11:00:02.000Z 2026-10-23T00:07:31.124Z https://longevityharbor.com/en/watch/9KZb0Ef-I-c Understanding Fibion Krono Reports for Sleep and Circadian Data – Dr. Olli Tikkanen https://i.ytimg.com/vi/9KZb0Ef-I-c/hqdefault.jpg Fibion Krono provides detailed, automatic sleep and circadian rhythm reports using validated multi-sensor data. Its TAP method outperforms traditional activity-only sleep estimation. ⏰ Timestamps: 00:00 🕒 Introduction to Fibion Krono and Its Sensors 00:30 🌙 How TAP Method Improves Sleep Detection 01:00 📊 Overview of Automated Sleep and Light Reports 02:00 🌡️ Temperature, Activity, and Light Data Breakdown 03:00 📈 Circadian Rhythm Graphs and Kronotype Classification 04:00 📋 Participant Feedback Based on Reported Data 05:30 💡 Insights into Sleep Habits and Light Exposure 07:00 🔄 Long-Term Monitoring: Battery and Memory Capacity 08:00 🧲 High-Precision Temperature Sensor and Off Detection 09:00 📞 Contact Info and How to Get Started Dr. Olli Tikkanen presents a comprehensive explanation of the Fibion Krono report features. The device measures light exposure, temperature, wrist position, and physical activity to deliver validated sleep and circadian rhythm insights. Its TAP method, tested against polysomnography (PSG), offers more reliable sleep detection than methods based solely on movement. Users receive fully automated reports through free software, with easy-to-understand visualizations and summaries. The Krono also supports participant feedback, daily activity visualization, and exportable raw data for researchers. Designed for long-term tracking, the device works up to 42 days on a single memory cycle and requires just one mid-cycle charge. Dr. Tikkanen also shares how the high-precision temperature sensor allows for advanced features like DLMO detection and off-body tracking. 📩 You can email Dr. Tikkanen at olli.tikkanen@fibion.com 📅 Schedule a video call with him: https://olli.tucalendi.com/par/videocall 💬 Contact directly via WhatsApp: +41 78 210 52 87 _____________ Discover Innovative Measurement Solutions for Your Research 🌟: _______________ 🆕 Elevate your research with Fibion SENS, the next-gen tool for monitoring physical activity and sedentary behavior. Discover the future: https://we https://www.youtube-nocookie.com/embed/9KZb0Ef-I-c 572 2025-04-19T08:52:29.000Z 2026-10-22T19:43:49.781Z https://longevityharbor.com/de/watch/9KZb0Ef-I-c Understanding Fibion Krono Reports for Sleep and Circadian Data – Dr. Olli Tikkanen https://i.ytimg.com/vi/9KZb0Ef-I-c/hqdefault.jpg Fibion Krono provides detailed, automatic sleep and circadian rhythm reports using validated multi-sensor data. Its TAP method outperforms traditional activity-only sleep estimation. ⏰ Timestamps: 00:00 🕒 Introduction to Fibion Krono and Its Sensors 00:30 🌙 How TAP Method Improves Sleep Detection 01:00 📊 Overview of Automated Sleep and Light Reports 02:00 🌡️ Temperature, Activity, and Light Data Breakdown 03:00 📈 Circadian Rhythm Graphs and Kronotype Classification 04:00 📋 Participant Feedback Based on Reported Data 05:30 💡 Insights into Sleep Habits and Light Exposure 07:00 🔄 Long-Term Monitoring: Battery and Memory Capacity 08:00 🧲 High-Precision Temperature Sensor and Off Detection 09:00 📞 Contact Info and How to Get Started Dr. Olli Tikkanen presents a comprehensive explanation of the Fibion Krono report features. The device measures light exposure, temperature, wrist position, and physical activity to deliver validated sleep and circadian rhythm insights. Its TAP method, tested against polysomnography (PSG), offers more reliable sleep detection than methods based solely on movement. Users receive fully automated reports through free software, with easy-to-understand visualizations and summaries. The Krono also supports participant feedback, daily activity visualization, and exportable raw data for researchers. Designed for long-term tracking, the device works up to 42 days on a single memory cycle and requires just one mid-cycle charge. Dr. Tikkanen also shares how the high-precision temperature sensor allows for advanced features like DLMO detection and off-body tracking. 📩 You can email Dr. Tikkanen at olli.tikkanen@fibion.com 📅 Schedule a video call with him: https://olli.tucalendi.com/par/videocall 💬 Contact directly via WhatsApp: +41 78 210 52 87 _____________ Discover Innovative Measurement Solutions for Your Research 🌟: _______________ 🆕 Elevate your research with Fibion SENS, the next-gen tool for monitoring physical activity and sedentary behavior. Discover the future: https://we https://www.youtube-nocookie.com/embed/9KZb0Ef-I-c 572 2025-04-19T08:52:29.000Z 2026-10-22T19:43:49.781Z https://longevityharbor.com/en/watch/9O3eeFESH8c USC|UCLA Geroscience Meeting Day 1 Afternoon https://i.ytimg.com/vi/9O3eeFESH8c/hqdefault.jpg USC|UCLA Geroscience Meeting: Integrating Social and Biological Hallmarks of Aging Day 1 Afternoon The Translational Geroscience Network: Biomarkers of Aging Processes and Interventions - James Kirkland (00:00:30) Universal transcriptomic hallmarks of aging and mortality across tissues, species, and chronic diseases (Aleksandr Tyshkovskii) (00:39:00) Are critical nuclear and mitochondrial genes missing from our omics database?(Brendan Miller) (01:02:30) Sex variation in the relationship between APOE ε4, cognitive decline, and dementia (Katrina Walsemann) (01:34:14) Wdr23 effects on ADRD in the context of APOE4 (Sean Curran) (01:54:35) Epigenetic G (Jessica Faul) (02:11:41) https://www.youtube-nocookie.com/embed/9O3eeFESH8c 9303 2025-04-16T22:17:36.000Z 2026-10-22T18:32:11.642Z https://longevityharbor.com/de/watch/9O3eeFESH8c USC|UCLA Geroscience Meeting Day 1 Afternoon https://i.ytimg.com/vi/9O3eeFESH8c/hqdefault.jpg USC|UCLA Geroscience Meeting: Integrating Social and Biological Hallmarks of Aging Day 1 Afternoon The Translational Geroscience Network: Biomarkers of Aging Processes and Interventions - James Kirkland (00:00:30) Universal transcriptomic hallmarks of aging and mortality across tissues, species, and chronic diseases (Aleksandr Tyshkovskii) (00:39:00) Are critical nuclear and mitochondrial genes missing from our omics database?(Brendan Miller) (01:02:30) Sex variation in the relationship between APOE ε4, cognitive decline, and dementia (Katrina Walsemann) (01:34:14) Wdr23 effects on ADRD in the context of APOE4 (Sean Curran) (01:54:35) Epigenetic G (Jessica Faul) (02:11:41) https://www.youtube-nocookie.com/embed/9O3eeFESH8c 9303 2025-04-16T22:17:36.000Z 2026-10-22T18:32:11.642Z https://longevityharbor.com/en/watch/9RWRTFfbwFk Seven Studies Just Proved We Can Reverse Functional Age https://i.ytimg.com/vi/9RWRTFfbwFk/hqdefault.jpg The final week of 2025 delivered a watershed moment for longevity science. Seven peer-reviewed publications and a landmark $292 million AI-driven biotech IPO signal that we have officially transitioned from merely slowing aging to actively reversing its functional deficits. This deep dive examines the four pillars now defining functional age reversal: zombie cell elimination, metabolic restoration through NAD+ therapy, autophagy activation via dietary intervention, and epigenetic reprogramming in humans. We break down Georgetown's senolytics research eliminating senescent cells, Cleveland Medical Center's NAD+ reversal of Alzheimer's pathology, the first human clinical trial measuring autophagy during fasting, and Life Biosciences' upcoming epigenetic reprogramming trials. Laboratory science has prepared for clinical translation. The financial markets have validated the approach. We are entering the era where functional age reversal transitions from speculative possibility to measurable clinical reality. Subscribe to Tomorrow Unveiled for insights into the technologies shaping our future. #LongevityScience #AgingReversal #NADTherapy #SenescentCells #Autophagy #BiologicalAge #HealthSpan #GeroScience #FunctionalMedicine #AIdrugDiscovery 📑 Chapters: 00:00:00 Intro 00:02:36 Zombie Cells Problem 00:05:35 Senolytic Treatments 00:10:19 Immune System Restoration 00:14:19 Metabolic Reversal Strategy 00:24:00 Clinical Translation Advances 00:28:30 Longevity Gap Challenge 00:33:40 Multimodal Treatment Approach 00:35:47 Future of Longevity Medicine https://www.youtube-nocookie.com/embed/9RWRTFfbwFk 2184 2025-12-31T16:00:16.000Z 2026-10-22T19:54:20.298Z https://longevityharbor.com/de/watch/9RWRTFfbwFk Seven Studies Just Proved We Can Reverse Functional Age https://i.ytimg.com/vi/9RWRTFfbwFk/hqdefault.jpg The final week of 2025 delivered a watershed moment for longevity science. Seven peer-reviewed publications and a landmark $292 million AI-driven biotech IPO signal that we have officially transitioned from merely slowing aging to actively reversing its functional deficits. This deep dive examines the four pillars now defining functional age reversal: zombie cell elimination, metabolic restoration through NAD+ therapy, autophagy activation via dietary intervention, and epigenetic reprogramming in humans. We break down Georgetown's senolytics research eliminating senescent cells, Cleveland Medical Center's NAD+ reversal of Alzheimer's pathology, the first human clinical trial measuring autophagy during fasting, and Life Biosciences' upcoming epigenetic reprogramming trials. Laboratory science has prepared for clinical translation. The financial markets have validated the approach. We are entering the era where functional age reversal transitions from speculative possibility to measurable clinical reality. Subscribe to Tomorrow Unveiled for insights into the technologies shaping our future. #LongevityScience #AgingReversal #NADTherapy #SenescentCells #Autophagy #BiologicalAge #HealthSpan #GeroScience #FunctionalMedicine #AIdrugDiscovery 📑 Chapters: 00:00:00 Intro 00:02:36 Zombie Cells Problem 00:05:35 Senolytic Treatments 00:10:19 Immune System Restoration 00:14:19 Metabolic Reversal Strategy 00:24:00 Clinical Translation Advances 00:28:30 Longevity Gap Challenge 00:33:40 Multimodal Treatment Approach 00:35:47 Future of Longevity Medicine https://www.youtube-nocookie.com/embed/9RWRTFfbwFk 2184 2025-12-31T16:00:16.000Z 2026-10-22T19:54:20.298Z https://longevityharbor.com/en/watch/9RdCg7_qWgM NMN & NAD+ The Next Generation Ingredient for Anti Aging https://i.ytimg.com/vi/9RdCg7_qWgM/hqdefault.jpg NMN (Nicotinamide Mononucleotide) is quickly emerging as one of the most exciting ingredients in both longevity research and advanced skincare. In this video, we explore: ✨ Why NMN is trending worldwide — from longevity science to the beauty industry ✨ The vital role of NAD+ in cellular energy, sirtuin activation, and DNA repair ✨ How NMN fuels NAD+ through the salvage pathway, acting as a fast-track precursor ✨ The challenge of skin application and the importance of delivery systems such as encapsulation, nano-emulsions, and liposomes ✨ Potential benefits for skin in terms of energy and recovery support 🌟 Key takeaway: NMN is not just a trend — it represents a new scientific perspective on anti-aging: restoring cellular energy as the foundation of healthy, youthful skin. 💡 Call to Action: Are you interested in developing skincare products with NMN? 📧 Contact us at: [ibteam@innopathintl.com] https://www.youtube-nocookie.com/embed/9RdCg7_qWgM 97 2025-09-30T02:50:54.000Z 2026-10-22T20:11:48.334Z https://longevityharbor.com/de/watch/9RdCg7_qWgM NMN & NAD+ The Next Generation Ingredient for Anti Aging https://i.ytimg.com/vi/9RdCg7_qWgM/hqdefault.jpg NMN (Nicotinamide Mononucleotide) is quickly emerging as one of the most exciting ingredients in both longevity research and advanced skincare. In this video, we explore: ✨ Why NMN is trending worldwide — from longevity science to the beauty industry ✨ The vital role of NAD+ in cellular energy, sirtuin activation, and DNA repair ✨ How NMN fuels NAD+ through the salvage pathway, acting as a fast-track precursor ✨ The challenge of skin application and the importance of delivery systems such as encapsulation, nano-emulsions, and liposomes ✨ Potential benefits for skin in terms of energy and recovery support 🌟 Key takeaway: NMN is not just a trend — it represents a new scientific perspective on anti-aging: restoring cellular energy as the foundation of healthy, youthful skin. 💡 Call to Action: Are you interested in developing skincare products with NMN? 📧 Contact us at: [ibteam@innopathintl.com] https://www.youtube-nocookie.com/embed/9RdCg7_qWgM 97 2025-09-30T02:50:54.000Z 2026-10-22T20:11:48.334Z https://longevityharbor.com/en/watch/9Rq0UN2mqQs Video description: astaxanthin and NMN presented as complementary, not competing https://i.ytimg.com/vi/9Rq0UN2mqQs/hqdefault.jpg The description presents NMN as supporting NAD+ production and astaxanthin as an antioxidant for cells, skin, eyes and recovery, and asks why choose between them. These are creator claims, not tested outcomes. https://www.youtube-nocookie.com/embed/9Rq0UN2mqQs 101 2026-08-27T13:08:49.000Z 2026-10-22T22:41:23.190Z https://longevityharbor.com/de/watch/9Rq0UN2mqQs Videobeschreibung: Astaxanthin und NMN als Ergänzung, nicht als Konkurrenz dargestellt https://i.ytimg.com/vi/9Rq0UN2mqQs/hqdefault.jpg Die Beschreibung stellt NMN als Unterstützung der NAD+-Bildung und Astaxanthin als Antioxidans für Zellen, Haut, Augen und Erholung dar und fragt, warum man wählen sollte. Das sind Aussagen des Erstellers, keine geprüften Ergebnisse. https://www.youtube-nocookie.com/embed/9Rq0UN2mqQs 101 2026-08-27T13:08:49.000Z 2026-10-22T22:41:23.190Z https://longevityharbor.com/en/watch/9UohVtV0C-8 Conference video: one-minute lightning talks on poster research in ageing biology https://i.ytimg.com/vi/9UohVtV0C-8/hqdefault.jpg The description presents a fast-paced competition in which presenters give one-minute overviews of their poster research on ageing biology and healthy longevity at the 2026 Geromedicine Conference. https://www.youtube-nocookie.com/embed/9UohVtV0C-8 995 2026-09-01T02:39:09.000Z 2026-10-22T22:35:59.063Z https://longevityharbor.com/de/watch/9UohVtV0C-8 Konferenzvideo: einminütige Lightning Talks zu Posterforschung in der Alternsbiologie https://i.ytimg.com/vi/9UohVtV0C-8/hqdefault.jpg Die Beschreibung stellt einen schnellen Wettbewerb vor, in dem Vortragende einminütige Überblicke ihrer Posterforschung zur Alternsbiologie und gesunden Langlebigkeit auf der Geromedicine-Konferenz 2026 geben. https://www.youtube-nocookie.com/embed/9UohVtV0C-8 995 2026-09-01T02:39:09.000Z 2026-10-22T22:35:59.063Z https://longevityharbor.com/en/watch/9W4b_pUDBdA Video description: senescent "zombie cells" and SASP in aging https://i.ytimg.com/vi/9W4b_pUDBdA/hqdefault.jpg The description says Dr. Ferehan Siraj Nuru explains cellular senescence, SASP and senolytics, describing senescent cells as no longer dividing yet avoiding normal clearance and releasing inflammatory molecules. https://www.youtube-nocookie.com/embed/9W4b_pUDBdA 100 2026-08-16T08:30:22.000Z 2026-10-22T22:58:29.511Z https://longevityharbor.com/de/watch/9W4b_pUDBdA Videobeschreibung: seneszente "Zombie-Zellen" und SASP beim Altern https://i.ytimg.com/vi/9W4b_pUDBdA/hqdefault.jpg Laut Beschreibung erklärt Dr. Ferehan Siraj Nuru zelluläre Seneszenz, SASP und Senolytika; seneszente Zellen teilen sich demnach nicht mehr, entgehen aber der normalen Beseitigung und setzen entzündliche Moleküle frei. https://www.youtube-nocookie.com/embed/9W4b_pUDBdA 100 2026-08-16T08:30:22.000Z 2026-10-22T22:58:29.511Z https://longevityharbor.com/en/watch/9XY_EoCclyY Kira Labs video asks what counts as evidence for extending healthy human life https://i.ytimg.com/vi/9XY_EoCclyY/hqdefault.jpg In this Kira Labs episode, Robert McMurrer says he explores what helps today, what scientists are testing and what would count as convincing evidence of life extension, from exercise to senescent cells and biological-age clocks. https://www.youtube-nocookie.com/embed/9XY_EoCclyY 452 2026-09-22T05:20:12.000Z 2026-10-22T21:58:30.365Z https://longevityharbor.com/de/watch/9XY_EoCclyY Kira-Labs-Video fragt, was als Beleg für ein längeres gesundes Leben gilt https://i.ytimg.com/vi/9XY_EoCclyY/hqdefault.jpg In dieser Kira-Labs-Folge sagt Robert McMurrer, er untersuche, was heute hilft, was Forschende testen und was als überzeugender Beleg für Lebensverlängerung gelten würde – von Bewegung bis zu seneszenten Zellen und biologischen Altersuhren. https://www.youtube-nocookie.com/embed/9XY_EoCclyY 452 2026-09-22T05:20:12.000Z 2026-10-22T21:58:30.365Z https://longevityharbor.com/en/watch/9aiPnVe7ZSo Video description: four claimed longevity priorities and a weekly protocol https://i.ytimg.com/vi/9aiPnVe7ZSo/hqdefault.jpg The description says longevity depends on four specific things, not supplements, and presents a framework, VO2 max as a top biomarker, an aging-research comparison and a weekly protocol. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/9aiPnVe7ZSo 687 2026-06-22T15:00:13.000Z 2026-10-22T23:53:03.682Z https://longevityharbor.com/de/watch/9aiPnVe7ZSo Videobeschreibung: vier behauptete Langlebigkeitsprioritäten und ein Wochenprotokoll https://i.ytimg.com/vi/9aiPnVe7ZSo/hqdefault.jpg Die Beschreibung sagt, Langlebigkeit hänge von vier konkreten Dingen ab, nicht von Nahrungsergänzungsmitteln, und stellt ein Rahmenkonzept, VO2 max als Top-Biomarker, einen Vergleich mit der Alternsforschung und ein Wochenprotokoll vor. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/9aiPnVe7ZSo 687 2026-06-22T15:00:13.000Z 2026-10-22T23:53:03.682Z https://longevityharbor.com/en/watch/9crQhOwlfsg 100-plus: Centenarians reveal their healthy-aging secrets https://i.ytimg.com/vi/9crQhOwlfsg/hqdefault.jpg You might think that living a full life past 100 is a stretch, but these centenarians say otherwise: They’re active, inspired and full of energy after 100-plus years and counting. They shared their New Year's resolutions in a commercial from Northwell Health, and now they’re revealing their thoughts on healthy aging. From diet and exercise to purpose, pets and stress, these centenarians share their wisdom on a life well lived. And joining us in the 20-Minute Health Talk studio with a professional perspective on healthy aging: Maria Carney, MD, FACP, chief of geriatric and palliative medicine at Northwell Health, and former health commissioner for Nassau County. Northwell Health is New York State’s largest healthcare provider and private employer, with 21 hospitals, 850 outpatient facilities and more than 16,600 affiliated physicians. We care for over two million people annually in the New York metro area and beyond, thanks to philanthropic support from our communities. Our 83,000 employees — 18,900 nurses and 4,900 employed doctors, including members of Northwell Health Physician Partners — are working to change health care for the better. We’re making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Interested in a career at Northwell Health? Visit http://bit.ly/2Z7iHFL and explore our many opportunities. The Well - https://thewell.northwell.edu/ Facebook – https://www.facebook.com/northwellhealth Instagram - https://www.instagram.com/northwellhealth X - https://www.x.com/northwellhealth LinkedIn - https://www.linkedin/northwellhealth https://www.youtube-nocookie.com/embed/9crQhOwlfsg 1271 2024-01-31T17:22:35.000Z 2026-10-22T18:43:11.764Z https://longevityharbor.com/de/watch/9crQhOwlfsg 100-plus: Centenarians reveal their healthy-aging secrets https://i.ytimg.com/vi/9crQhOwlfsg/hqdefault.jpg You might think that living a full life past 100 is a stretch, but these centenarians say otherwise: They’re active, inspired and full of energy after 100-plus years and counting. They shared their New Year's resolutions in a commercial from Northwell Health, and now they’re revealing their thoughts on healthy aging. From diet and exercise to purpose, pets and stress, these centenarians share their wisdom on a life well lived. And joining us in the 20-Minute Health Talk studio with a professional perspective on healthy aging: Maria Carney, MD, FACP, chief of geriatric and palliative medicine at Northwell Health, and former health commissioner for Nassau County. Northwell Health is New York State’s largest healthcare provider and private employer, with 21 hospitals, 850 outpatient facilities and more than 16,600 affiliated physicians. We care for over two million people annually in the New York metro area and beyond, thanks to philanthropic support from our communities. Our 83,000 employees — 18,900 nurses and 4,900 employed doctors, including members of Northwell Health Physician Partners — are working to change health care for the better. We’re making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Interested in a career at Northwell Health? Visit http://bit.ly/2Z7iHFL and explore our many opportunities. The Well - https://thewell.northwell.edu/ Facebook – https://www.facebook.com/northwellhealth Instagram - https://www.instagram.com/northwellhealth X - https://www.x.com/northwellhealth LinkedIn - https://www.linkedin/northwellhealth https://www.youtube-nocookie.com/embed/9crQhOwlfsg 1271 2024-01-31T17:22:35.000Z 2026-10-22T18:43:11.764Z https://longevityharbor.com/en/watch/9dGbHvQr3oI Longevity: Wie Lukas sein Altern verlangsamt | 37 Grad https://i.ytimg.com/vi/9dGbHvQr3oI/hqdefault.jpg Lukas folgt täglich einer festen Routine, zu der Supplements, Infusionen, Rotlicht- und Kältetherapie gehören. 🎥 Die Erstveröffentlichung und Langfassung der Doku “Alles für Longevity” findest du beim ZDF: https://kurz.zdf.de/pBC9Mb/ 🔔 Keine Doku verpassen? JETZT abonnieren: https://kurz.zdf.de/XHcf/ - mehr schauen: https://kurz.zdf.de/cVIx/ #StoryOfMyLife #37Grad #ZDF Für Lukas bedeutet Longevity nicht nur ein langes, sondern vor allem ein gesundes Leben. Longevity - wörtlich „Langlebigkeit“. Dieser Idee ordnet Lukas jedes Mittel unter: Geld, Sport, Schlaf und Ernährung. Dinge, auf die er keine Lust hat, lässt er weg. Jeder Tag beginnt um 6 Uhr mit Meditation, gefolgt von 20 Minuten unter der Rotlichtlampe und einer sorgfältigen Skincare-Routine. Ein Glas Wasser mit Apfelessig und ein Proteinshake dürfen ebenso wenig fehlen wie diverse Nahrungsergänzungsmittel. Viele davon hat Lukas selbst entwickelt. Mit 18 Jahren startet Lukas seine Karriere als internationales Model. Der Druck, den vermeintlich perfekten Körper zu zeigen, hinterlässt Spuren. Er probiert unzählige Diäten aus, bis er nicht mehr kann. Eine Reise nach Indien und eine Yogalehrer-Ausbildung verändern seine Sicht auf sich selbst und seinen Körper. Heute ist Lukas Unternehmer. Digitaler Detox und Eisbaden gehören zu seinem Alltag wie die Kontrolle über jede Minute. Er sucht nach immer neuen Wegen, den Alterungsprozess zu verlangsamen. Psychologe Lukas Klaschinski sieht in der Langlebigkeitsszene ein komplexes Phänomen: Das Streben nach Kontrolle übers Älterwerden kann Kraft geben, aber auch zum Zwang werden und wenig Platz für Spontanität lassen. Für Lukas überwiegen die Vorteile: Körperliche und mentale Gesundheit stehen für ihn an erster Stelle. „Mir ist egal, was andere über mich denken.“ Was bleibt, ist die Hoffnung, gemeinsam mit seinen engsten Menschen möglichst lange glücklich zu leben. 🎥 Hat dir dieses Video gefallen? Lass uns ein Like da! Noch mehr 37 Grad: 🎬 Mobbing in der Schule: https://www.youtube.com/watch?v=Aua0CB5QM98 🎬 https://www.youtube-nocookie.com/embed/9dGbHvQr3oI 821 2025-10-15T15:00:32.000Z 2026-10-22T18:43:10.929Z https://longevityharbor.com/de/watch/9dGbHvQr3oI Longevity: Wie Lukas sein Altern verlangsamt | 37 Grad https://i.ytimg.com/vi/9dGbHvQr3oI/hqdefault.jpg Lukas folgt täglich einer festen Routine, zu der Supplements, Infusionen, Rotlicht- und Kältetherapie gehören. 🎥 Die Erstveröffentlichung und Langfassung der Doku “Alles für Longevity” findest du beim ZDF: https://kurz.zdf.de/pBC9Mb/ 🔔 Keine Doku verpassen? JETZT abonnieren: https://kurz.zdf.de/XHcf/ - mehr schauen: https://kurz.zdf.de/cVIx/ #StoryOfMyLife #37Grad #ZDF Für Lukas bedeutet Longevity nicht nur ein langes, sondern vor allem ein gesundes Leben. Longevity - wörtlich „Langlebigkeit“. Dieser Idee ordnet Lukas jedes Mittel unter: Geld, Sport, Schlaf und Ernährung. Dinge, auf die er keine Lust hat, lässt er weg. Jeder Tag beginnt um 6 Uhr mit Meditation, gefolgt von 20 Minuten unter der Rotlichtlampe und einer sorgfältigen Skincare-Routine. Ein Glas Wasser mit Apfelessig und ein Proteinshake dürfen ebenso wenig fehlen wie diverse Nahrungsergänzungsmittel. Viele davon hat Lukas selbst entwickelt. Mit 18 Jahren startet Lukas seine Karriere als internationales Model. Der Druck, den vermeintlich perfekten Körper zu zeigen, hinterlässt Spuren. Er probiert unzählige Diäten aus, bis er nicht mehr kann. Eine Reise nach Indien und eine Yogalehrer-Ausbildung verändern seine Sicht auf sich selbst und seinen Körper. Heute ist Lukas Unternehmer. Digitaler Detox und Eisbaden gehören zu seinem Alltag wie die Kontrolle über jede Minute. Er sucht nach immer neuen Wegen, den Alterungsprozess zu verlangsamen. Psychologe Lukas Klaschinski sieht in der Langlebigkeitsszene ein komplexes Phänomen: Das Streben nach Kontrolle übers Älterwerden kann Kraft geben, aber auch zum Zwang werden und wenig Platz für Spontanität lassen. Für Lukas überwiegen die Vorteile: Körperliche und mentale Gesundheit stehen für ihn an erster Stelle. „Mir ist egal, was andere über mich denken.“ Was bleibt, ist die Hoffnung, gemeinsam mit seinen engsten Menschen möglichst lange glücklich zu leben. 🎥 Hat dir dieses Video gefallen? Lass uns ein Like da! Noch mehr 37 Grad: 🎬 Mobbing in der Schule: https://www.youtube.com/watch?v=Aua0CB5QM98 🎬 https://www.youtube-nocookie.com/embed/9dGbHvQr3oI 821 2025-10-15T15:00:32.000Z 2026-10-22T18:43:10.929Z https://longevityharbor.com/en/watch/9k17zsGErv4 Video description claims fading melatonin may make sleep harder after 70 https://i.ytimg.com/vi/9k17zsGErv4/hqdefault.jpg The description says melatonin, described as the natural sleep hormone, declines with age and that this makes falling and staying asleep harder for people over 70. It presents light exposure, a consistent sleep routine and small lifestyle changes as ways to help reset the internal clock. https://www.youtube-nocookie.com/embed/9k17zsGErv4 122 2026-04-01T02:30:00.000Z 2026-10-23T01:49:47.586Z https://longevityharbor.com/de/watch/9k17zsGErv4 Videobeschreibung: sinkendes Melatonin könnte Schlaf nach 70 erschweren https://i.ytimg.com/vi/9k17zsGErv4/hqdefault.jpg Die Beschreibung sagt, Melatonin – als natürliches Schlafhormon bezeichnet – nehme mit dem Alter ab und mache es Menschen über 70 schwerer, ein- und durchzuschlafen. Sie nennt Lichtexposition, eine gleichbleibende Schlafroutine und kleine Lebensstiländerungen als Wege, die innere Uhr zurückzusetzen. https://www.youtube-nocookie.com/embed/9k17zsGErv4 122 2026-04-01T02:30:00.000Z 2026-10-23T01:49:47.586Z https://longevityharbor.com/en/watch/9mVUbF6qvzs Video description: epigenetic clocks, heart risk and proposed RNA prevention https://i.ytimg.com/vi/9mVUbF6qvzs/hqdefault.jpg The description presents GrimAge, DunedinPACE and PhenoAge as biological-age measures and cites MESA data linking GrimAge acceleration to cardiovascular events; the RNA-therapy prevention vision is proposed, not established. https://www.youtube-nocookie.com/embed/9mVUbF6qvzs 107 2026-09-07T13:18:35.000Z 2026-10-22T22:27:48.019Z https://longevityharbor.com/de/watch/9mVUbF6qvzs Videobeschreibung: epigenetische Uhren, Herzrisiko und vorgeschlagene RNA-Prävention https://i.ytimg.com/vi/9mVUbF6qvzs/hqdefault.jpg Die Beschreibung stellt GrimAge, DunedinPACE und PhenoAge als Maße des biologischen Alters vor und nennt MESA-Daten, die beschleunigtes GrimAge mit kardiovaskulären Ereignissen verbinden; die RNA-Therapie-Vision ist ein Vorschlag, nicht belegt. https://www.youtube-nocookie.com/embed/9mVUbF6qvzs 107 2026-09-07T13:18:35.000Z 2026-10-22T22:27:48.019Z https://longevityharbor.com/en/watch/9ngANQwOCBA Exercise, Muscle Signals and Metabolic Health: A Video Description Explainer https://i.ytimg.com/vi/9ngANQwOCBA/hqdefault.jpg The description says muscle helps regulate blood sugar and supports healthy aging, and that Dr. Dorothea Schlesinger explains how exercise affects insulin sensitivity, how working muscles release signals called myokines, and what research suggests about exercise and mood. https://www.youtube-nocookie.com/embed/9ngANQwOCBA 225 2026-10-12T20:25:30.000Z 2026-10-22T20:12:50.382Z https://longevityharbor.com/de/watch/9ngANQwOCBA Bewegung, Muskelsignale und Stoffwechselgesundheit: Ein Erklärstück zur Videobeschreibung https://i.ytimg.com/vi/9ngANQwOCBA/hqdefault.jpg Laut Beschreibung hilft Muskulatur, den Blutzucker zu regulieren und gesundes Altern zu unterstützen; Dr. Dorothea Schlesinger erklärt darin, wie Bewegung die Insulinempfindlichkeit beeinflusst, wie arbeitende Muskeln Signalstoffe namens Myokine freisetzen und was Forschung zu Bewegung und Stimmung nahelegt. https://www.youtube-nocookie.com/embed/9ngANQwOCBA 225 2026-10-12T20:25:30.000Z 2026-10-22T20:12:50.382Z https://longevityharbor.com/en/watch/9u8IvvZ0_xE Video description: breakfast, protein and muscle loss over 60 https://i.ytimg.com/vi/9u8IvvZ0_xE/hqdefault.jpg The description says the video explains why protein and a balanced diet matter after 60 and which protein-rich foods suit a breakfast, with movement also named as important. https://www.youtube-nocookie.com/embed/9u8IvvZ0_xE 799 2026-09-30T16:38:50.000Z 2026-10-22T21:36:46.332Z https://longevityharbor.com/de/watch/9u8IvvZ0_xE Videobeschreibung: Frühstück, Eiweiß und Muskelabbau über 60 https://i.ytimg.com/vi/9u8IvvZ0_xE/hqdefault.jpg Laut Beschreibung erklärt das Video, warum Eiweiß und eine ausgewogene Ernährung nach 60 wichtig sind und welche proteinreichen Lebensmittel für ein Frühstück passen; auch Bewegung wird als wichtig genannt. https://www.youtube-nocookie.com/embed/9u8IvvZ0_xE 799 2026-09-30T16:38:50.000Z 2026-10-22T21:36:46.332Z https://longevityharbor.com/en/watch/9vTTHb8D-8s Webinar description: senolytics plus in-situ exosomes as a proposed regenerative strategy https://i.ytimg.com/vi/9vTTHb8D-8s/hqdefault.jpg The description says Dr. Capt Arvind Poswal's webinar presents a proposed regenerative approach that pairs senolytics with in-situ exosome activation, arguing that clearing dysfunctional senescent cells should come before regenerative signaling. It is aimed at doctors, researchers and medically informed professionals. https://www.youtube-nocookie.com/embed/9vTTHb8D-8s 2769 2026-01-21T07:06:44.000Z 2026-10-23T02:48:59.287Z https://longevityharbor.com/de/watch/9vTTHb8D-8s Webinar-Beschreibung: Senolytika plus In-situ-Exosomen als vorgeschlagene regenerative Strategie https://i.ytimg.com/vi/9vTTHb8D-8s/hqdefault.jpg Laut Beschreibung stellt das Webinar von Dr. Capt Arvind Poswal einen vorgeschlagenen regenerativen Ansatz vor, der Senolytika mit In-situ-Exosomen-Aktivierung kombiniert, und argumentiert, dass das Entfernen dysfunktionaler seneszenter Zellen vor regenerativen Signalen kommen sollte. Es richtet sich an Ärztinnen und Ärzte, Forschende und medizinisch informierte Fachleute. https://www.youtube-nocookie.com/embed/9vTTHb8D-8s 2769 2026-01-21T07:06:44.000Z 2026-10-23T02:48:59.287Z https://longevityharbor.com/en/watch/A7eLsNJCRMA Video description: seven fasting approaches and how the body switches fuels https://i.ytimg.com/vi/A7eLsNJCRMA/hqdefault.jpg The description says this educational lecture covers seven fasting approaches and how the body shifts between recently eaten food, stored glycogen and stored fat; it states longer or more extreme fasting is not automatically better. https://www.youtube-nocookie.com/embed/A7eLsNJCRMA 2867 2026-09-21T20:34:14.000Z 2026-10-22T21:58:46.699Z https://longevityharbor.com/de/watch/A7eLsNJCRMA Videobeschreibung: sieben Fastenansätze und der Brennstoffwechsel des Körpers https://i.ytimg.com/vi/A7eLsNJCRMA/hqdefault.jpg Laut Beschreibung behandelt diese Lehrvorlesung sieben Fastenansätze und wie der Körper zwischen kürzlich gegessener Nahrung, gespeichertem Glykogen und gespeichertem Fett wechselt; längeres oder extremeres Fasten sei nicht automatisch besser. https://www.youtube-nocookie.com/embed/A7eLsNJCRMA 2867 2026-09-21T20:34:14.000Z 2026-10-22T21:58:46.699Z https://longevityharbor.com/en/watch/ACJ5qi46XW4 Circadian Rhythm and Intermittent Fasting for Healthy Lifespan https://i.ytimg.com/vi/ACJ5qi46XW4/hqdefault.jpg Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body’s internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body’s response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. [Show ID: 40733] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/ACJ5qi46XW4 5278 2025-11-08T03:00:20.000Z 2026-10-22T18:54:02.151Z https://longevityharbor.com/de/watch/ACJ5qi46XW4 Circadian Rhythm and Intermittent Fasting for Healthy Lifespan https://i.ytimg.com/vi/ACJ5qi46XW4/hqdefault.jpg Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body’s internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body’s response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. [Show ID: 40733] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/ACJ5qi46XW4 5278 2025-11-08T03:00:20.000Z 2026-10-22T18:54:02.151Z https://longevityharbor.com/en/watch/AHdzEfy4Nkk LONGEVITY: The Science of Aging and How to Turn On Your Longevity Genes to Live Longer https://i.ytimg.com/vi/AHdzEfy4Nkk/hqdefault.jpg Dr. Rajsree Nambudripad, MD is board-certified in Internal Medicine and founder of OC Integrative Medicine in Fullerton, California. In this video, Dr. Rajsree explains the science of aging and all the factors that affect your longevity, from genetics, to diet, exercise, exposures, and lifestyle. What's the difference between Lifespan and Healthspan? Biological Age vs. Chronological Age? What are the hallmarks of aging? Learn about Sirtuins, AMKP, and mTOR, and Autophagy and how they impact your longevity. How does the gut microbiome impact your Longevity? How does chronic inflammation affect Longevity? She reviews the latest science on Diet, Lifestyle, and Supplements to promote health and longevity. 00:00 Introduction 00:42 Lifespan vs. Healthspan 01:31 Outward Signs of Aging 01:57 Proactive and Preventative Approach to Health and Longevity 02:20 Key Lab Biomarkers 03:45 Chronological Age vs. Biological Age 04:18 Supercentenarians 04:31 Factor Influencing Longevity 05:03 Hallmarks of Aging 08:23 Epigenetic Clock 08:59 Sirtuins, AMPK, and mTOR 13:30 Autophagy 14:58 Time Restricted Eating 16:00 Gut Microbiome and Longevity 17:19 Inflammation and Longevity 17:48 Inflammaging 18:43 Sugar and Advanced Glycation Endproducts 20:18 David Sinclair, PhD and Information Theory of Aging 20:48 Yamanaka Genes (Fountain of Youth Genes) 21:14 The Future: Gene Therapy and Senolytics 22:22 Blue Zones 23:47 Diet: Key Principles 25:35 Intermittent Fasting 26:31 Exercise 27:20 Hormesis 28:09 Supplements to Improve Your Healthspan 29:53 Berberine for Insulin Resistance 30:42 Sleep 31:02 Minimize Exposure to Toxins 31:44 Relationships with People 32:17 Case Example: Mike 32:40 Key Points ➡️Watch Dr. Rajsree's video on Autophagy: https://www.youtube.com/watch?v=v5xBE1zvwUY&t=430s ➡️ Watch Dr. Rajsree's video on Insulin Resistance (Paleo Diet): https://www.youtube.com/watch?v=9swHzLLRCAg&t=768s ➡️ Watch Dr. Rajsree's video on Clean Keto Diet: https://www.youtube.com/watch?v=DP9-oKeWZco&t=2025s 🧡 Shop for Supplements by D https://www.youtube-nocookie.com/embed/AHdzEfy4Nkk 2008 2023-02-12T15:05:05.000Z 2026-10-22T17:43:39.310Z https://longevityharbor.com/de/watch/AHdzEfy4Nkk LONGEVITY: The Science of Aging and How to Turn On Your Longevity Genes to Live Longer https://i.ytimg.com/vi/AHdzEfy4Nkk/hqdefault.jpg Dr. Rajsree Nambudripad, MD is board-certified in Internal Medicine and founder of OC Integrative Medicine in Fullerton, California. In this video, Dr. Rajsree explains the science of aging and all the factors that affect your longevity, from genetics, to diet, exercise, exposures, and lifestyle. What's the difference between Lifespan and Healthspan? Biological Age vs. Chronological Age? What are the hallmarks of aging? Learn about Sirtuins, AMKP, and mTOR, and Autophagy and how they impact your longevity. How does the gut microbiome impact your Longevity? How does chronic inflammation affect Longevity? She reviews the latest science on Diet, Lifestyle, and Supplements to promote health and longevity. 00:00 Introduction 00:42 Lifespan vs. Healthspan 01:31 Outward Signs of Aging 01:57 Proactive and Preventative Approach to Health and Longevity 02:20 Key Lab Biomarkers 03:45 Chronological Age vs. Biological Age 04:18 Supercentenarians 04:31 Factor Influencing Longevity 05:03 Hallmarks of Aging 08:23 Epigenetic Clock 08:59 Sirtuins, AMPK, and mTOR 13:30 Autophagy 14:58 Time Restricted Eating 16:00 Gut Microbiome and Longevity 17:19 Inflammation and Longevity 17:48 Inflammaging 18:43 Sugar and Advanced Glycation Endproducts 20:18 David Sinclair, PhD and Information Theory of Aging 20:48 Yamanaka Genes (Fountain of Youth Genes) 21:14 The Future: Gene Therapy and Senolytics 22:22 Blue Zones 23:47 Diet: Key Principles 25:35 Intermittent Fasting 26:31 Exercise 27:20 Hormesis 28:09 Supplements to Improve Your Healthspan 29:53 Berberine for Insulin Resistance 30:42 Sleep 31:02 Minimize Exposure to Toxins 31:44 Relationships with People 32:17 Case Example: Mike 32:40 Key Points ➡️Watch Dr. Rajsree's video on Autophagy: https://www.youtube.com/watch?v=v5xBE1zvwUY&t=430s ➡️ Watch Dr. Rajsree's video on Insulin Resistance (Paleo Diet): https://www.youtube.com/watch?v=9swHzLLRCAg&t=768s ➡️ Watch Dr. Rajsree's video on Clean Keto Diet: https://www.youtube.com/watch?v=DP9-oKeWZco&t=2025s 🧡 Shop for Supplements by D https://www.youtube-nocookie.com/embed/AHdzEfy4Nkk 2008 2023-02-12T15:05:05.000Z 2026-10-22T17:43:39.310Z https://longevityharbor.com/en/watch/AKUn6tpvYRI Podcast conversation on rapamycin, mTOR and longevity research https://i.ytimg.com/vi/AKUn6tpvYRI/hqdefault.jpg In this podcast description, Matt Kaeberlein discusses how mTOR research shaped views of aging, why rapamycin is debated, and what human trials can and cannot show so far. https://www.youtube-nocookie.com/embed/AKUn6tpvYRI 3221 2026-09-16T16:10:41.000Z 2026-10-22T22:10:17.891Z https://longevityharbor.com/de/watch/AKUn6tpvYRI Podcast-Gespräch über Rapamycin, mTOR und Langlebigkeitsforschung https://i.ytimg.com/vi/AKUn6tpvYRI/hqdefault.jpg In dieser Podcast-Beschreibung erläutert Matt Kaeberlein, wie die mTOR-Forschung das Verständnis des Alterns prägte, warum Rapamycin umstritten ist und was menschliche Studien bisher zeigen können und was nicht. https://www.youtube-nocookie.com/embed/AKUn6tpvYRI 3221 2026-09-16T16:10:41.000Z 2026-10-22T22:10:17.891Z https://longevityharbor.com/en/watch/AMsDDM76wXg Genomics PhD describes his own diet, supplements and DNA-repair focus https://i.ytimg.com/vi/AMsDDM76wXg/hqdefault.jpg In this video description, Brazilian genomics PhD Ricardo di Lazzaro Filho outlines his personal diet, supplements, exercise and sleep habits and says DNA repair is his main longevity focus. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/AMsDDM76wXg 5841 2026-06-07T15:00:34.000Z 2026-10-23T00:06:44.751Z https://longevityharbor.com/de/watch/AMsDDM76wXg Genomik-Promovierter beschreibt eigene Ernährung, Supplemente und DNA-Reparatur-Fokus https://i.ytimg.com/vi/AMsDDM76wXg/hqdefault.jpg In dieser Videobeschreibung skizziert der brasilianische Genomik-Promovierte Ricardo di Lazzaro Filho seine persönliche Ernährung, Supplemente, Bewegung und Schlafgewohnheiten und nennt DNA-Reparatur seinen wichtigsten Langlebigkeitsfokus. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/AMsDDM76wXg 5841 2026-06-07T15:00:34.000Z 2026-10-23T00:06:44.751Z https://longevityharbor.com/en/watch/AR1JX50YoqM Video description: nutrition, protein and strength training for belly fat after 50 https://i.ytimg.com/vi/AR1JX50YoqM/hqdefault.jpg The description says the video covers nutrition, protein, strength training, everyday movement and underestimated eating habits for losing belly fat after 50, and states that belly fat does not disappear through abdominal exercises alone. https://www.youtube-nocookie.com/embed/AR1JX50YoqM 905 2026-08-21T16:01:05.000Z 2026-10-22T22:49:32.987Z https://longevityharbor.com/de/watch/AR1JX50YoqM Videobeschreibung: Ernährung, Protein und Krafttraining gegen Bauchfett ab 50 https://i.ytimg.com/vi/AR1JX50YoqM/hqdefault.jpg Laut Beschreibung behandelt das Video Ernährung, Protein, Krafttraining, Alltagsbewegung und unterschätzte Essgewohnheiten beim Abnehmen von Bauchfett ab 50 und sagt, dass Bauchfett nicht allein durch Bauchübungen verschwindet. https://www.youtube-nocookie.com/embed/AR1JX50YoqM 905 2026-08-21T16:01:05.000Z 2026-10-22T22:49:32.987Z https://longevityharbor.com/en/watch/AUGbiesMT3I Geroscience and Healthy Longevity with Anthony Molina https://i.ytimg.com/vi/AUGbiesMT3I/hqdefault.jpg Aging research has come a long way in the past few decades, and scientists are now starting to understand the biology of aging. Anthony J.A. Molina, Ph.D., shares the latest findings in the field of geroscience, or the study of how to delay the onset of age-related diseases and extend healthy lifespan. [3/2023] [Show ID: 38634] 00:00 Start 00:50 Main Presentation 36:13 Audience Q&A Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/AUGbiesMT3I 3250 2023-03-05T03:00:04.000Z 2026-10-22T17:43:40.119Z https://longevityharbor.com/de/watch/AUGbiesMT3I Geroscience and Healthy Longevity with Anthony Molina https://i.ytimg.com/vi/AUGbiesMT3I/hqdefault.jpg Aging research has come a long way in the past few decades, and scientists are now starting to understand the biology of aging. Anthony J.A. Molina, Ph.D., shares the latest findings in the field of geroscience, or the study of how to delay the onset of age-related diseases and extend healthy lifespan. [3/2023] [Show ID: 38634] 00:00 Start 00:50 Main Presentation 36:13 Audience Q&A Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/AUGbiesMT3I 3250 2023-03-05T03:00:04.000Z 2026-10-22T17:43:40.119Z https://longevityharbor.com/en/watch/AXLuFxvOxP8 Video description claims senolytics and habits can reverse cellular senescence https://i.ytimg.com/vi/AXLuFxvOxP8/hqdefault.jpg The description says aging cells stop dividing but do not die and release inflammatory molecules, and claims senolytics, quercetin, fisetin and daily habits can reverse this. These are creator claims, not results reviewed here. https://www.youtube-nocookie.com/embed/AXLuFxvOxP8 501 2026-08-29T15:00:12.000Z 2026-10-22T22:39:32.720Z https://longevityharbor.com/de/watch/AXLuFxvOxP8 Videobeschreibung behauptet, Senolytika und Gewohnheiten könnten zelluläre Seneszenz umkehren https://i.ytimg.com/vi/AXLuFxvOxP8/hqdefault.jpg Die Beschreibung sagt, alternde Zellen teilen sich nicht mehr, sterben aber nicht und setzen entzündliche Moleküle frei; Senolytika, Quercetin, Fisetin und Alltagsgewohnheiten könnten dies umkehren. Das sind Aussagen des Erstellers, keine hier geprüften Ergebnisse. https://www.youtube-nocookie.com/embed/AXLuFxvOxP8 501 2026-08-29T15:00:12.000Z 2026-10-22T22:39:32.720Z https://longevityharbor.com/en/watch/AZF8oFRtXkg Lecture on hallmarks of aging, resilience loss and Dunedin study findings https://i.ytimg.com/vi/AZF8oFRtXkg/hqdefault.jpg The description presents a lecture linking loss of physiological resiliency to poor aging outcomes and cites Dunedin Longitudinal Study findings from ages 26 to 45; it also promotes paid longevity and nutrition programs. https://www.youtube-nocookie.com/embed/AZF8oFRtXkg 898 2026-01-06T12:30:23.000Z 2026-10-23T02:57:30.874Z https://longevityharbor.com/de/watch/AZF8oFRtXkg Vortrag über Hallmarks des Alterns, Resilienzverlust und Befunde der Dunedin-Studie https://i.ytimg.com/vi/AZF8oFRtXkg/hqdefault.jpg Die Beschreibung stellt einen Vortrag vor, der Verlust physiologischer Resilienz mit schlechten Alterungsverläufen verbindet und Befunde der Dunedin-Längsschnittstudie von Alter 26 bis 45 nennt; zudem werden kostenpflichtige Longevity- und Ernährungsprogramme beworben. https://www.youtube-nocookie.com/embed/AZF8oFRtXkg 898 2026-01-06T12:30:23.000Z 2026-10-23T02:57:30.874Z https://longevityharbor.com/en/watch/AZle4T67ncU Video discussion: longevity access, policy and aging as a treatable condition https://i.ytimg.com/vi/AZle4T67ncU/hqdefault.jpg In this video description, Kaushik Trivedi and Dylan Livingston discuss aging as a driver of disease and a potentially treatable condition, note that current longevity solutions favor the wealthy, and call for policy and broader access. https://www.youtube-nocookie.com/embed/AZle4T67ncU 3746 2026-03-23T17:17:48.000Z 2026-10-23T01:58:56.462Z https://longevityharbor.com/de/watch/AZle4T67ncU Videogespräch: Zugang zu Langlebigkeit, Politik und Altern als behandelbarer Zustand https://i.ytimg.com/vi/AZle4T67ncU/hqdefault.jpg In dieser Videobeschreibung erörtern Kaushik Trivedi und Dylan Livingston Altern als Krankheitstreiber und potenziell behandelbaren Zustand, merken an, dass heutige Langlebigkeitslösungen Wohlhabende begünstigen, und fordern Politik und breiteren Zugang. https://www.youtube-nocookie.com/embed/AZle4T67ncU 3746 2026-03-23T17:17:48.000Z 2026-10-23T01:58:56.462Z https://longevityharbor.com/en/watch/A_aaBKubJnA Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks https://i.ytimg.com/vi/A_aaBKubJnA/hqdefault.jpg Steve Horvath, PhD, ScD is a professor of human genetics and biostatistics at UCLA's Fielding School of Public Health. Dr. Horvath is the creator of the Horvath Epigenetic Aging Clock. His work incorporates elements of biostatistics, genetics, epidemiology, epigenomics, and other fields of study. He applies his understanding of this diverse range of disciplines to study a spectrum of chronic diseases, including cancer, cardiovascular disease, neurodegenerative disease, and other diseases of aging. Dr. Horvath's so-called "pan-tissue epigenetic aging clock" is an algorithm that accurately predicts a person's chronological age from marks on the DNA across multiple cells, tissues, and organs, and even mammalian species. Further refining this initial algorithm, Dr. Horvath built on this to develop second-generation clock algorithm that could predict time-to-death among people of the same chronological age, as well as lifespan and healthspan. One of these clocks, the GrimAge clock, is named deliberately after its connotation: predicting time until death ("Grim"). In this episode, Dr. Steven Horvath describes epigenetic clocks and their role in predicting – and possibly slowing – aging EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/steve-horvath?utm_source=youtube&utm_medium=youtube&utm_campaign=horvath_interview Dr. Steve Horvath's faculty bio page: https://ph.ucla.edu/faculty/horvath Dr. Steve Horvath's Wikipedia page: https://en.wikipedia.org/wiki/Steve_Horvath PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=horvath_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/062-dr-steve-horvath-on-epigenetic-aging-to-predict/id818198322?i=1000503234644 Spotify: https://open.spotify.com/episode/0jMd5uqKjzCyFU3CpDMxix Full interview playlist: https://www.youtube.com/playlist?list=PLJEEAVzHu9KzgkQbe2Thh35VU-HCiId_s Clips playlist: https://www.youtube.com/playlist?list=PLrGxo-5Uw8gI9-1IStYEvNxVukKxZBlmi Dr. R https://www.youtube-nocookie.com/embed/A_aaBKubJnA 4390 2020-12-22T16:50:43.000Z 2026-10-22T17:43:35.334Z https://longevityharbor.com/de/watch/A_aaBKubJnA Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks https://i.ytimg.com/vi/A_aaBKubJnA/hqdefault.jpg Steve Horvath, PhD, ScD is a professor of human genetics and biostatistics at UCLA's Fielding School of Public Health. Dr. Horvath is the creator of the Horvath Epigenetic Aging Clock. His work incorporates elements of biostatistics, genetics, epidemiology, epigenomics, and other fields of study. He applies his understanding of this diverse range of disciplines to study a spectrum of chronic diseases, including cancer, cardiovascular disease, neurodegenerative disease, and other diseases of aging. Dr. Horvath's so-called "pan-tissue epigenetic aging clock" is an algorithm that accurately predicts a person's chronological age from marks on the DNA across multiple cells, tissues, and organs, and even mammalian species. Further refining this initial algorithm, Dr. Horvath built on this to develop second-generation clock algorithm that could predict time-to-death among people of the same chronological age, as well as lifespan and healthspan. One of these clocks, the GrimAge clock, is named deliberately after its connotation: predicting time until death ("Grim"). In this episode, Dr. Steven Horvath describes epigenetic clocks and their role in predicting – and possibly slowing – aging EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/steve-horvath?utm_source=youtube&utm_medium=youtube&utm_campaign=horvath_interview Dr. Steve Horvath's faculty bio page: https://ph.ucla.edu/faculty/horvath Dr. Steve Horvath's Wikipedia page: https://en.wikipedia.org/wiki/Steve_Horvath PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=horvath_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/062-dr-steve-horvath-on-epigenetic-aging-to-predict/id818198322?i=1000503234644 Spotify: https://open.spotify.com/episode/0jMd5uqKjzCyFU3CpDMxix Full interview playlist: https://www.youtube.com/playlist?list=PLJEEAVzHu9KzgkQbe2Thh35VU-HCiId_s Clips playlist: https://www.youtube.com/playlist?list=PLrGxo-5Uw8gI9-1IStYEvNxVukKxZBlmi Dr. R https://www.youtube-nocookie.com/embed/A_aaBKubJnA 4390 2020-12-22T16:50:43.000Z 2026-10-22T17:43:35.334Z https://longevityharbor.com/en/watch/Am03B4dKOd4 💡 EP#3 The NEWEST Advances in Cosmetics Science: Cell Senescence, AI & more! https://i.ytimg.com/vi/Am03B4dKOd4/hqdefault.jpg Join Dr. David Manzano, R&I Manager at Provital, in an enlightening discussion with Clara Vigo, Product Manager about the latest advances in COSMETICS! Step into the benefits of Altheostem™, a multi-awarded active ingredient. Don't miss out on this engaging episode as we unravel the future of cosmetic science and the dynamic partnership between technology and beauty. Let us know in the comments your thoughts or any question! We will be happy to answer you. HIGHLIGHTS [00:00] Intro [02:18] Introducing the concept of Cell Senescence [06:57] Inside Altheostem™ senolytic effect [08:15] How we evaluate and quantify the senolytic activity in vitro [12:25] Using AI innovative tools 👉 Do you want to know more about Altheostem™? https://t.ly/EMjGx ABOUT PROVITAL We co-create with our clients high-quality cosmetic ingredients combining Nature and Science. We DO CARE for people, communities and the planet. Web: https://www.weareprovital.com/en Linkedin: https://www.linkedin.com/company/weareprovital/ Contact: marketing@weareprovital.com #Altheostem #CosmeticResearch #AI #CellSenescence #CosmeticScience #Podcast https://www.youtube-nocookie.com/embed/Am03B4dKOd4 847 2024-02-26T09:34:10.000Z 2026-10-22T19:21:23.245Z https://longevityharbor.com/de/watch/Am03B4dKOd4 💡 EP#3 The NEWEST Advances in Cosmetics Science: Cell Senescence, AI & more! https://i.ytimg.com/vi/Am03B4dKOd4/hqdefault.jpg Join Dr. David Manzano, R&I Manager at Provital, in an enlightening discussion with Clara Vigo, Product Manager about the latest advances in COSMETICS! Step into the benefits of Altheostem™, a multi-awarded active ingredient. Don't miss out on this engaging episode as we unravel the future of cosmetic science and the dynamic partnership between technology and beauty. Let us know in the comments your thoughts or any question! We will be happy to answer you. HIGHLIGHTS [00:00] Intro [02:18] Introducing the concept of Cell Senescence [06:57] Inside Altheostem™ senolytic effect [08:15] How we evaluate and quantify the senolytic activity in vitro [12:25] Using AI innovative tools 👉 Do you want to know more about Altheostem™? https://t.ly/EMjGx ABOUT PROVITAL We co-create with our clients high-quality cosmetic ingredients combining Nature and Science. We DO CARE for people, communities and the planet. Web: https://www.weareprovital.com/en Linkedin: https://www.linkedin.com/company/weareprovital/ Contact: marketing@weareprovital.com #Altheostem #CosmeticResearch #AI #CellSenescence #CosmeticScience #Podcast https://www.youtube-nocookie.com/embed/Am03B4dKOd4 847 2024-02-26T09:34:10.000Z 2026-10-22T19:21:23.245Z https://longevityharbor.com/en/watch/AmWx9NuM2Dk The ONE Exercise That ACTIVATES Your Lymphatic System After Age 60 https://i.ytimg.com/vi/AmWx9NuM2Dk/hqdefault.jpg What if one of the simplest movements you can do after 60 could help support your body’s natural lymphatic circulation — without expensive machines, complicated workouts, or extreme exercise? In this science-based video, we explore **how the lymphatic system works after age 60** and why everyday rhythmic movement can play an important role in supporting normal fluid circulation throughout the body. You’ll discover the science behind the **calf muscle pump, walking, diaphragmatic breathing, gentle movement, water-based exercise, and a simple 10-minute routine** that can easily fit into your daily lifestyle. We also examine the popular **mini-trampoline and rebounder trend**, including the commonly mentioned NASA research, and explain why that research does **not actually prove that rebounding is superior for lymphatic circulation**. Most importantly, you’ll learn practical, low-impact movements you can perform at home with little or no equipment — especially if your goal is to stay active, mobile, and healthy as you get older. This video covers: • Lymphatic system and aging • How movement supports lymphatic circulation • The calf muscle pump explained • Walking after 60 • Deep diaphragmatic breathing • Gentle exercises for older adults • Water-based exercise and circulation • A simple 10-minute movement routine • Mini-trampoline and rebounder claims • Swelling and fluid retention • Healthy aging and mobility • When swelling may require medical attention If you’re **over 60 and interested in healthy aging, circulation, mobility, lymphatic health, and simple science-backed movement**, this video is for you. **Disclaimer:** This video is for educational purposes only and is not medical advice. If you have lymphedema, have had lymph nodes removed, are undergoing cancer treatment, or have new, painful, one-sided swelling, consult your doctor or a qualified healthcare professional before starting a new exercise routine. #FeynmanWisdom #LymphaticSystem #HealthyAging #LymphaticHealth #After60 #Over60Health #Healt https://www.youtube-nocookie.com/embed/AmWx9NuM2Dk 1208 2026-10-06T13:00:07.000Z 2026-10-22T19:21:29.765Z https://longevityharbor.com/de/watch/AmWx9NuM2Dk The ONE Exercise That ACTIVATES Your Lymphatic System After Age 60 https://i.ytimg.com/vi/AmWx9NuM2Dk/hqdefault.jpg What if one of the simplest movements you can do after 60 could help support your body’s natural lymphatic circulation — without expensive machines, complicated workouts, or extreme exercise? In this science-based video, we explore **how the lymphatic system works after age 60** and why everyday rhythmic movement can play an important role in supporting normal fluid circulation throughout the body. You’ll discover the science behind the **calf muscle pump, walking, diaphragmatic breathing, gentle movement, water-based exercise, and a simple 10-minute routine** that can easily fit into your daily lifestyle. We also examine the popular **mini-trampoline and rebounder trend**, including the commonly mentioned NASA research, and explain why that research does **not actually prove that rebounding is superior for lymphatic circulation**. Most importantly, you’ll learn practical, low-impact movements you can perform at home with little or no equipment — especially if your goal is to stay active, mobile, and healthy as you get older. This video covers: • Lymphatic system and aging • How movement supports lymphatic circulation • The calf muscle pump explained • Walking after 60 • Deep diaphragmatic breathing • Gentle exercises for older adults • Water-based exercise and circulation • A simple 10-minute movement routine • Mini-trampoline and rebounder claims • Swelling and fluid retention • Healthy aging and mobility • When swelling may require medical attention If you’re **over 60 and interested in healthy aging, circulation, mobility, lymphatic health, and simple science-backed movement**, this video is for you. **Disclaimer:** This video is for educational purposes only and is not medical advice. If you have lymphedema, have had lymph nodes removed, are undergoing cancer treatment, or have new, painful, one-sided swelling, consult your doctor or a qualified healthcare professional before starting a new exercise routine. #FeynmanWisdom #LymphaticSystem #HealthyAging #LymphaticHealth #After60 #Over60Health #Healt https://www.youtube-nocookie.com/embed/AmWx9NuM2Dk 1208 2026-10-06T13:00:07.000Z 2026-10-22T19:21:29.765Z https://longevityharbor.com/en/watch/Aod4ZDhrh88 Video description: sleep, circadian timing and melatonin's effect on glucose https://i.ytimg.com/vi/Aod4ZDhrh88/hqdefault.jpg The description says the same meal causes higher glucose peaks and slower clearance at night than in the morning, and that melatonin taken with food can worsen glucose tolerance. https://www.youtube-nocookie.com/embed/Aod4ZDhrh88 1255 2026-08-18T21:00:26.000Z 2026-10-22T22:56:27.038Z https://longevityharbor.com/de/watch/Aod4ZDhrh88 Videobeschreibung: Schlaf, circadiane Zeitgebung und Melatonins Wirkung auf Glukose https://i.ytimg.com/vi/Aod4ZDhrh88/hqdefault.jpg Laut Beschreibung führt dieselbe Mahlzeit abends zu höheren Glukosespitzen und langsamerer Clearance als morgens, und Melatonin zum Essen kann die Glukosetoleranz verschlechtern. https://www.youtube-nocookie.com/embed/Aod4ZDhrh88 1255 2026-08-18T21:00:26.000Z 2026-10-22T22:56:27.038Z https://longevityharbor.com/en/watch/Arue-KaDcHQ This Doctor Proved Aging Can Be Stopped Before It Starts https://i.ytimg.com/vi/Arue-KaDcHQ/hqdefault.jpg Can aging be stopped before it starts? Dr. Nir Barzilai reveals the science-backed longevity protocol to prevent age-related diseases and reverse your biological clock. Dr. Mark Hyman is joined by Dr. Nir Barzilai, a leading geroscientist and the founder of the Einstein Nathan Shock Center. Together, they break down the critical difference between chronological age and the actual biology of aging, revealing how we can target aging at its root source to dramatically extend our clinical health span. Dr. Barzilai shares his personal longevity routine—including intermittent fasting, strict daily exercise, and sleep habits—while diving deep into his groundbreaking research on "SuperAgers." Discover why certain genetic traits, like surprisingly low IGF-1 (growth hormone) levels, protect centenarians from chronic disease, and how everyday people can mimic these effects. We also explore the controversial truth about metformin, the highly anticipated TAME trial, and why simply chasing the newest peptides or taking 100-supplement stacks might be doing more harm than good. If you want to understand the future of evidence-based longevity medicine without the biohacking hype, this conversation is for you. #Longevity #AntiAging #Metformin #DrMarkHyman #SuperAgers Get my FREE guide 3 Steps to Reverse Aging when you sign up for my weekly health picks 👉 https://bit.ly/IncreaseHealthspan View the Show Notes For This Episode: https://bit.ly/ep-852 This episode is brought to you by Sunlighten, Cozy Earth, BiOptimizers, and Fatty 15. For a limited time, you can save up to $600 on a Sunlighten infrared sauna. Just go to https://sunlighten.com/mark-hyman and mention my name. Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to https://CozyEarth.com and use code DRHYMAN. Tackle an overlooked root cause of stress with Magnesium Breakthrough. Visit https://bioptimizers.com/hyman and use code HYMAN10 to save 10% and get a free gift with purchase. Fatty15 contains pure, award-winning C15:0 in a b https://www.youtube-nocookie.com/embed/Arue-KaDcHQ 5945 2024-02-07T11:00:08.000Z 2026-10-22T18:32:10.869Z https://longevityharbor.com/de/watch/Arue-KaDcHQ This Doctor Proved Aging Can Be Stopped Before It Starts https://i.ytimg.com/vi/Arue-KaDcHQ/hqdefault.jpg Can aging be stopped before it starts? Dr. Nir Barzilai reveals the science-backed longevity protocol to prevent age-related diseases and reverse your biological clock. Dr. Mark Hyman is joined by Dr. Nir Barzilai, a leading geroscientist and the founder of the Einstein Nathan Shock Center. Together, they break down the critical difference between chronological age and the actual biology of aging, revealing how we can target aging at its root source to dramatically extend our clinical health span. Dr. Barzilai shares his personal longevity routine—including intermittent fasting, strict daily exercise, and sleep habits—while diving deep into his groundbreaking research on "SuperAgers." Discover why certain genetic traits, like surprisingly low IGF-1 (growth hormone) levels, protect centenarians from chronic disease, and how everyday people can mimic these effects. We also explore the controversial truth about metformin, the highly anticipated TAME trial, and why simply chasing the newest peptides or taking 100-supplement stacks might be doing more harm than good. If you want to understand the future of evidence-based longevity medicine without the biohacking hype, this conversation is for you. #Longevity #AntiAging #Metformin #DrMarkHyman #SuperAgers Get my FREE guide 3 Steps to Reverse Aging when you sign up for my weekly health picks 👉 https://bit.ly/IncreaseHealthspan View the Show Notes For This Episode: https://bit.ly/ep-852 This episode is brought to you by Sunlighten, Cozy Earth, BiOptimizers, and Fatty 15. For a limited time, you can save up to $600 on a Sunlighten infrared sauna. Just go to https://sunlighten.com/mark-hyman and mention my name. Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to https://CozyEarth.com and use code DRHYMAN. Tackle an overlooked root cause of stress with Magnesium Breakthrough. Visit https://bioptimizers.com/hyman and use code HYMAN10 to save 10% and get a free gift with purchase. Fatty15 contains pure, award-winning C15:0 in a b https://www.youtube-nocookie.com/embed/Arue-KaDcHQ 5945 2024-02-07T11:00:08.000Z 2026-10-22T18:32:10.869Z https://longevityharbor.com/en/watch/AvUrcbwAd1Y Fact-checking anti-aging meds | Metformin, Rapamycin, NMN, etc https://i.ytimg.com/vi/AvUrcbwAd1Y/hqdefault.jpg A scientific look at the most popular anti-aging drugs & supplements Connect with me: Facebook: https://www.facebook.com/DrGilCarvalho/ Twitter: https://twitter.com/NutritionMadeS3 Animations: Even Topland @toplandmedia References: Metformin https://www.tandfonline.com/doi/pdf/10.4161/CC.7.17.6625 https://www.nature.com/articles/ncomms3192 https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2021.718942/full Diabetes Prevention Program: https://pmc.ncbi.nlm.nih.gov/articles/PMC3135022/pdf/nihms299552.pdf Metformin & exercise: https://onlinelibrary.wiley.com/doi/full/10.1111/acel.12880 Metformin & testosterone: https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2021.813067/full Rapamycin & aging: https://link.springer.com/content/pdf/10.1007/s11357-020-00274-1.pdf https://pmc.ncbi.nlm.nih.gov/articles/PMC4397165/pdf/nihms669810.pdf mTOR inhibition & immunity: https://pubmed.ncbi.nlm.nih.gov/25540326/ NAD: https://www.sciencedirect.com/science/article/pii/S053155652300030X NMN / NR: https://onlinelibrary.wiley.com/doi/full/10.1002/jcsm.13799 Niacin: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2730481 https://www.sciencedirect.com/science/article/abs/pii/S0002934316310580 Psyllium: https://pmc.ncbi.nlm.nih.gov/articles/PMC7652639/ https://www.sciencedirect.com/science/article/pii/S1756464623002852 https://www.sciencedirect.com/science/article/pii/S0002916523070107 https://www.sciencedirect.com/science/article/pii/S0002916523272354 Betaine: https://journals.lww.com/nsca-jscr/fulltext/2017/08000/effects_of_betaine_supplementation_on_muscle.35.aspx https://journals.lww.com/nsca-jscr/fulltext/2011/12000/The_Effects_of_Chronic_Betaine_Supplementation_on.31.aspx Magnesium: https://www.sciencedirect.com/science/article/abs/pii/S0021915011004734 Vitamin K2: www.youtube.com/watch?v=nkPEfVzm6io https://www.ahajournals.org/doi/pdf/10.1161/circulationaha.121.057008 Collagen peptides: https://www.sciencedirect.com/science/article/abs/pii/S030541791830637 https://www.youtube-nocookie.com/embed/AvUrcbwAd1Y 2919 2025-05-05T13:00:31.000Z 2026-10-22T19:54:21.237Z https://longevityharbor.com/de/watch/AvUrcbwAd1Y Fact-checking anti-aging meds | Metformin, Rapamycin, NMN, etc https://i.ytimg.com/vi/AvUrcbwAd1Y/hqdefault.jpg A scientific look at the most popular anti-aging drugs & supplements Connect with me: Facebook: https://www.facebook.com/DrGilCarvalho/ Twitter: https://twitter.com/NutritionMadeS3 Animations: Even Topland @toplandmedia References: Metformin https://www.tandfonline.com/doi/pdf/10.4161/CC.7.17.6625 https://www.nature.com/articles/ncomms3192 https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2021.718942/full Diabetes Prevention Program: https://pmc.ncbi.nlm.nih.gov/articles/PMC3135022/pdf/nihms299552.pdf Metformin & exercise: https://onlinelibrary.wiley.com/doi/full/10.1111/acel.12880 Metformin & testosterone: https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2021.813067/full Rapamycin & aging: https://link.springer.com/content/pdf/10.1007/s11357-020-00274-1.pdf https://pmc.ncbi.nlm.nih.gov/articles/PMC4397165/pdf/nihms669810.pdf mTOR inhibition & immunity: https://pubmed.ncbi.nlm.nih.gov/25540326/ NAD: https://www.sciencedirect.com/science/article/pii/S053155652300030X NMN / NR: https://onlinelibrary.wiley.com/doi/full/10.1002/jcsm.13799 Niacin: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2730481 https://www.sciencedirect.com/science/article/abs/pii/S0002934316310580 Psyllium: https://pmc.ncbi.nlm.nih.gov/articles/PMC7652639/ https://www.sciencedirect.com/science/article/pii/S1756464623002852 https://www.sciencedirect.com/science/article/pii/S0002916523070107 https://www.sciencedirect.com/science/article/pii/S0002916523272354 Betaine: https://journals.lww.com/nsca-jscr/fulltext/2017/08000/effects_of_betaine_supplementation_on_muscle.35.aspx https://journals.lww.com/nsca-jscr/fulltext/2011/12000/The_Effects_of_Chronic_Betaine_Supplementation_on.31.aspx Magnesium: https://www.sciencedirect.com/science/article/abs/pii/S0021915011004734 Vitamin K2: www.youtube.com/watch?v=nkPEfVzm6io https://www.ahajournals.org/doi/pdf/10.1161/circulationaha.121.057008 Collagen peptides: https://www.sciencedirect.com/science/article/abs/pii/S030541791830637 https://www.youtube-nocookie.com/embed/AvUrcbwAd1Y 2919 2025-05-05T13:00:31.000Z 2026-10-22T19:54:21.237Z https://longevityharbor.com/en/watch/AwBPnKIs1eI Creator's proposed Brain First framework for aging after 40 https://i.ytimg.com/vi/AwBPnKIs1eI/hqdefault.jpg The description presents a proposed Brain First approach to healthy aging after 40, saying supplements, peptides, NAD+, cold plunges and other tools are not themselves an implementation strategy. https://www.youtube-nocookie.com/embed/AwBPnKIs1eI 463 2026-10-07T13:57:13.000Z 2026-10-22T21:13:40.426Z https://longevityharbor.com/de/watch/AwBPnKIs1eI Vorgeschlagenes Brain-First-Konzept des Erstellers fürs Altern ab 40 https://i.ytimg.com/vi/AwBPnKIs1eI/hqdefault.jpg Die Beschreibung stellt einen vorgeschlagenen Brain-First-Ansatz für gesundes Altern ab 40 vor und sagt, Nahrungsergänzungsmittel, Peptide, NAD+, Kaltbäder und andere Werkzeuge seien für sich keine Umsetzungsstrategie. https://www.youtube-nocookie.com/embed/AwBPnKIs1eI 463 2026-10-07T13:57:13.000Z 2026-10-22T21:13:40.426Z https://longevityharbor.com/en/watch/Ayeqs1Hv5jM Think You're Aging Gracefully? Your Epigenetic Clock Just Rolled Its Eyes https://i.ytimg.com/vi/Ayeqs1Hv5jM/hqdefault.jpg #DNAClock #EpigeneticBurn #BloodKnowsBest #OldInside https://www.youtube-nocookie.com/embed/Ayeqs1Hv5jM 340 2025-10-09T07:30:05.000Z 2026-10-22T18:54:04.067Z https://longevityharbor.com/de/watch/Ayeqs1Hv5jM Think You're Aging Gracefully? Your Epigenetic Clock Just Rolled Its Eyes https://i.ytimg.com/vi/Ayeqs1Hv5jM/hqdefault.jpg #DNAClock #EpigeneticBurn #BloodKnowsBest #OldInside https://www.youtube-nocookie.com/embed/Ayeqs1Hv5jM 340 2025-10-09T07:30:05.000Z 2026-10-22T18:54:04.067Z https://longevityharbor.com/en/watch/Az9GFHqCrmI Die beste Ernährung für ein gesundes Altern https://i.ytimg.com/vi/Az9GFHqCrmI/hqdefault.jpg Die beste Ernährung für ein gesundes Altern https://www.youtube-nocookie.com/embed/Az9GFHqCrmI 411 2025-08-15T07:00:20.000Z 2026-10-22T18:43:10.934Z https://longevityharbor.com/de/watch/Az9GFHqCrmI Die beste Ernährung für ein gesundes Altern https://i.ytimg.com/vi/Az9GFHqCrmI/hqdefault.jpg Die beste Ernährung für ein gesundes Altern https://www.youtube-nocookie.com/embed/Az9GFHqCrmI 411 2025-08-15T07:00:20.000Z 2026-10-22T18:43:10.934Z https://longevityharbor.com/en/watch/B3--k8ORQVo The Hallmarks of Aging | LifeXtenShow https://i.ytimg.com/vi/B3--k8ORQVo/hqdefault.jpg Let's face it: you're getting old, but there's a reason—or, rather, there's nine. This episode is all about the hallmarks of aging, the microscopic conspirators inside your body that are plotting to slowly take away your health. Liked the show? Let us know on Twitter at https://twitter.com/lifespanio or our Discord server at https://discord.gg/HwTX7gR Facebook: https://www.facebook.com/lifespanio/ LinkedIn: https://www.linkedin.com/company/lifespanio Instagram: https://www.instagram.com/lifespan.io Website: https://www.leafscience.org/ Stock contents: Shutterstock, Videoblocks Music: Intro jingle courtesy of Kevin MacLeod - Incompetech.com -------------------------- Sources: The Hallmarks of Aging: López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. Cell, 153(6), 1194-1217. (Available for free here: https://www.cell.com/abstract/S0092-8674(13)00645-4) Oncogenes can be flipped on epigenetically: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422217/ Senescent cells and wound healing: https://www.sciencedaily.com/releases/2014/12/141211124526.htm Insulin resistance in human aging: Chen, M., Bergman, R. N., Pacini, G., & Porte Jr, D. (1985). Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased β-cell function. The Journal of Clinical Endocrinology & Metabolism, 60(1), 13-20. -------------------------- #Aging #Biology #HallmarksOfAging #Science #LifeExtension #Telomeres #Mitochondria #Epigenetics #DNADamage #CellularSenescence #NutrientSensing #Inflammation #StemCells #Proteins #Proteostasis ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a Lifespan Hero: http://lifespan.io/hero https://www.youtube-nocookie.com/embed/B3--k8ORQVo 992 2019-09-05T15:08:46.000Z 2026-10-22T17:43:40.122Z https://longevityharbor.com/de/watch/B3--k8ORQVo The Hallmarks of Aging | LifeXtenShow https://i.ytimg.com/vi/B3--k8ORQVo/hqdefault.jpg Let's face it: you're getting old, but there's a reason—or, rather, there's nine. This episode is all about the hallmarks of aging, the microscopic conspirators inside your body that are plotting to slowly take away your health. Liked the show? Let us know on Twitter at https://twitter.com/lifespanio or our Discord server at https://discord.gg/HwTX7gR Facebook: https://www.facebook.com/lifespanio/ LinkedIn: https://www.linkedin.com/company/lifespanio Instagram: https://www.instagram.com/lifespan.io Website: https://www.leafscience.org/ Stock contents: Shutterstock, Videoblocks Music: Intro jingle courtesy of Kevin MacLeod - Incompetech.com -------------------------- Sources: The Hallmarks of Aging: López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. Cell, 153(6), 1194-1217. (Available for free here: https://www.cell.com/abstract/S0092-8674(13)00645-4) Oncogenes can be flipped on epigenetically: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422217/ Senescent cells and wound healing: https://www.sciencedaily.com/releases/2014/12/141211124526.htm Insulin resistance in human aging: Chen, M., Bergman, R. N., Pacini, G., & Porte Jr, D. (1985). Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased β-cell function. The Journal of Clinical Endocrinology & Metabolism, 60(1), 13-20. -------------------------- #Aging #Biology #HallmarksOfAging #Science #LifeExtension #Telomeres #Mitochondria #Epigenetics #DNADamage #CellularSenescence #NutrientSensing #Inflammation #StemCells #Proteins #Proteostasis ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a Lifespan Hero: http://lifespan.io/hero https://www.youtube-nocookie.com/embed/B3--k8ORQVo 992 2019-09-05T15:08:46.000Z 2026-10-22T17:43:40.122Z https://longevityharbor.com/en/watch/BDbJc4Q1-ts Podcast description: circadian skin clock, chrono skincare and a device pending FDA clearance https://i.ytimg.com/vi/BDbJc4Q1-ts/hqdefault.jpg The description says dermatologists Dr. Patti Farris and Dr. Ava Shamban discuss circadian rhythms in skin, clock genes, screen time and night shifts, chrono skincare, Dr. Ava's Althea line and a planned at-home device pending FDA clearance. https://www.youtube-nocookie.com/embed/BDbJc4Q1-ts 1536 2026-05-26T13:00:11.000Z 2026-10-23T00:25:51.133Z https://longevityharbor.com/de/watch/BDbJc4Q1-ts Podcast-Beschreibung: circadiane Hautuhr, Chrono-Hautpflege und ein Gerät vor der FDA-Zulassung https://i.ytimg.com/vi/BDbJc4Q1-ts/hqdefault.jpg Laut Beschreibung sprechen die Dermatologinnen Dr. Patti Farris und Dr. Ava Shamban über circadiane Rhythmen der Haut, Uhr-Gene, Bildschirmzeit und Nachtschichten, Chrono-Hautpflege, Dr. Avas Linie Althea und ein geplantes Heimgerät, dessen FDA-Zulassung noch aussteht. https://www.youtube-nocookie.com/embed/BDbJc4Q1-ts 1536 2026-05-26T13:00:11.000Z 2026-10-23T00:25:51.133Z https://longevityharbor.com/en/watch/BEXvCOcmlnM Video description: rapamycin from Rapa Nui soil and its proposed role in slowing ageing https://i.ytimg.com/vi/BEXvCOcmlnM/hqdefault.jpg According to the description, rapamycin was first isolated from soil on Rapa Nui (Easter Island) and initially looked like another antifungal. The creator says the video explains how rapamycin works, why it is central to longevity research, and whether it could be the first drug to meaningfully slow ageing. https://www.youtube-nocookie.com/embed/BEXvCOcmlnM 477 2026-04-06T17:41:08.000Z 2026-10-23T01:40:38.130Z https://longevityharbor.com/de/watch/BEXvCOcmlnM Videobeschreibung: Rapamycin aus Boden von Rapa Nui und seine vorgeschlagene Rolle beim Bremsen des https://i.ytimg.com/vi/BEXvCOcmlnM/hqdefault.jpg Laut der Beschreibung wurde Rapamycin erstmals aus Boden auf Rapa Nui (Osterinsel) isoliert und wirkte zunächst wie ein weiteres Antimykotikum. Der Ersteller sagt, das Video erkläre, wie Rapamycin wirkt, warum es in der Langlebigkeitsforschung zentral ist und ob es das erste Medikament sein könnte, das das Altern deutlich bremst. https://www.youtube-nocookie.com/embed/BEXvCOcmlnM 477 2026-04-06T17:41:08.000Z 2026-10-23T01:40:38.130Z https://longevityharbor.com/en/watch/BGFb3Hf0HJU Slide video on measuring biological age and aging–chronic disease links https://i.ytimg.com/vi/BGFb3Hf0HJU/hqdefault.jpg The creator describes a slide video summarizing a presentation on measuring biological age with clinical biomarkers and on how aging relates to chronic disease; the description says the slides are only briefly summarized. https://www.youtube-nocookie.com/embed/BGFb3Hf0HJU 1465 2026-08-23T08:10:54.000Z 2026-10-22T22:48:42.486Z https://longevityharbor.com/de/watch/BGFb3Hf0HJU Folienvideo zur Messung des biologischen Alters und zu Alter-Krankheits-Bezügen https://i.ytimg.com/vi/BGFb3Hf0HJU/hqdefault.jpg Der Ersteller beschreibt ein Folienvideo, das einen Vortrag zur Messung des biologischen Alters mit klinischen Biomarkern und zum Zusammenhang von Altern und chronischen Krankheiten zusammenfasst; laut Beschreibung werden die Folien nur kurz angerissen. https://www.youtube-nocookie.com/embed/BGFb3Hf0HJU 1465 2026-08-23T08:10:54.000Z 2026-10-22T22:48:42.486Z https://longevityharbor.com/en/watch/BHY0FxzoKZE The Brain-Changing Benefits of Exercise | Wendy Suzuki | TED https://i.ytimg.com/vi/BHY0FxzoKZE/hqdefault.jpg What's the most transformative thing that you can do for your brain today? Exercise! says neuroscientist Wendy Suzuki. Get inspired to go to the gym as Suzuki discusses the science of how working out boosts your mood and memory -- and protects your brain against neurodegenerative diseases like Alzheimer's. Visit http://TED.com to get our entire library of TED Talks, transcripts, translations, personalized talk recommendations and more. The TED Talks channel features the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and more. You're welcome to link to or embed these videos, forward them to others and share these ideas with people you know. Become a TED Member: http://ted.com/membership Follow TED on Twitter: http://twitter.com/TEDTalks Like TED on Facebook: http://facebook.com/TED Subscribe to our channel: http://youtube.com/TED TED's videos may be used for non-commercial purposes under a Creative Commons License, Attribution–Non Commercial–No Derivatives (or the CC BY – NC – ND 4.0 International) and in accordance with our TED Talks Usage Policy https://www.ted.com/about/our-organization/our-policies-terms/ted-talks-usage-policy. For more information on using TED for commercial purposes (e.g. employee learning, in a film or online course), please submit a Media Request at https://media-requests.ted.com https://www.youtube-nocookie.com/embed/BHY0FxzoKZE 783 2018-03-21T14:53:46.000Z 2026-10-22T17:43:36.897Z https://longevityharbor.com/de/watch/BHY0FxzoKZE The Brain-Changing Benefits of Exercise | Wendy Suzuki | TED https://i.ytimg.com/vi/BHY0FxzoKZE/hqdefault.jpg What's the most transformative thing that you can do for your brain today? Exercise! says neuroscientist Wendy Suzuki. Get inspired to go to the gym as Suzuki discusses the science of how working out boosts your mood and memory -- and protects your brain against neurodegenerative diseases like Alzheimer's. Visit http://TED.com to get our entire library of TED Talks, transcripts, translations, personalized talk recommendations and more. The TED Talks channel features the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and more. You're welcome to link to or embed these videos, forward them to others and share these ideas with people you know. Become a TED Member: http://ted.com/membership Follow TED on Twitter: http://twitter.com/TEDTalks Like TED on Facebook: http://facebook.com/TED Subscribe to our channel: http://youtube.com/TED TED's videos may be used for non-commercial purposes under a Creative Commons License, Attribution–Non Commercial–No Derivatives (or the CC BY – NC – ND 4.0 International) and in accordance with our TED Talks Usage Policy https://www.ted.com/about/our-organization/our-policies-terms/ted-talks-usage-policy. For more information on using TED for commercial purposes (e.g. employee learning, in a film or online course), please submit a Media Request at https://media-requests.ted.com https://www.youtube-nocookie.com/embed/BHY0FxzoKZE 783 2018-03-21T14:53:46.000Z 2026-10-22T17:43:36.897Z https://longevityharbor.com/en/watch/BI1hB-me8jo Video description compares NMN and NR as NAD⁺ boosters for anti-aging https://i.ytimg.com/vi/BI1hB-me8jo/hqdefault.jpg The description presents a video titled as a comparison of NMN and NR as NAD⁺ boosters for anti-aging and points to a linked article said to be research-backed. It gives no study results, doses or outcomes. https://www.youtube-nocookie.com/embed/BI1hB-me8jo 96 2026-02-25T17:09:15.000Z 2026-10-23T02:19:47.861Z https://longevityharbor.com/de/watch/BI1hB-me8jo Videobeschreibung vergleicht NMN und NR als NAD⁺-Booster für Anti-Aging https://i.ytimg.com/vi/BI1hB-me8jo/hqdefault.jpg Die Beschreibung stellt ein Video vor, das NMN und NR als NAD⁺-Booster für Anti-Aging vergleicht, und verweist auf einen verlinkten, laut Beschreibung forschungsgestützten Artikel. Ergebnisse, Dosierungen oder Endpunkte nennt sie nicht. https://www.youtube-nocookie.com/embed/BI1hB-me8jo 96 2026-02-25T17:09:15.000Z 2026-10-23T02:19:47.861Z https://longevityharbor.com/en/watch/BJHaUS1madk Barzilai video description: geroscience, centenarians and drugs like metformin https://i.ytimg.com/vi/BJHaUS1madk/hqdefault.jpg The description says Barzilai links aging biology to chronic disease and discusses centenarians, GLP-1 therapies, metformin, biomarkers and FDA regulation. It is a description only; video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/BJHaUS1madk 3631 2026-06-15T09:57:56.000Z 2026-10-22T23:57:58.844Z https://longevityharbor.com/de/watch/BJHaUS1madk Barzilai-Videobeschreibung: Geroscience, Hundertjährige und Wirkstoffe wie Metformin https://i.ytimg.com/vi/BJHaUS1madk/hqdefault.jpg Laut Beschreibung verbindet Barzilai Alternsbiologie mit chronischen Krankheiten und spricht über Hundertjährige, GLP-1-Therapien, Metformin, Biomarker und FDA-Regulierung. Es ist nur eine Beschreibung; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/BJHaUS1madk 3631 2026-06-15T09:57:56.000Z 2026-10-22T23:57:58.844Z https://longevityharbor.com/en/watch/BKrcFRb9n-E Healthy Aging: The Challenge of Sarcopenia and Functioning https://i.ytimg.com/vi/BKrcFRb9n-E/hqdefault.jpg The Jeffrey Palmer, M.D. Endowed Lectureship is made possible by the Jeffrey Palmer, M.D. Lectureship Endowed Fund. This fund was established to support the continued education of faculty, residents, and trainees by fostering engagement in a professional environment that highlights research and scientific advancements in Physical Medicine and Rehabilitation and related fields. #healthyaging #johnshopkins #sarcopenia #physicalactivity #exercisebenefits https://www.hopkinsmedicine.org/physical-medicine-rehabilitation/education-training/jeffrey-palmer-lectureship Lecture Details: Presenter: Walter R. Frontera, M.D., Ph.D., F.R.C.P. Date: October 14, 2025 Presentation Description: Life expectancy and the number of older adults have increased significantly over the last century. Aging is associated with a progressive loss of functional capacity and independence, with sarcopenia recognized as a major contributor to this decline. In this recorded lecture, Dr. Frontera reviews recent scientific advances that have deepened our understanding of sarcopenia and discusses evidence-based rehabilitation strategies aimed at improving function in affected individuals. https://www.youtube-nocookie.com/embed/BKrcFRb9n-E 3972 2025-10-31T13:50:07.000Z 2026-10-22T17:43:36.931Z https://longevityharbor.com/de/watch/BKrcFRb9n-E Healthy Aging: The Challenge of Sarcopenia and Functioning https://i.ytimg.com/vi/BKrcFRb9n-E/hqdefault.jpg The Jeffrey Palmer, M.D. Endowed Lectureship is made possible by the Jeffrey Palmer, M.D. Lectureship Endowed Fund. This fund was established to support the continued education of faculty, residents, and trainees by fostering engagement in a professional environment that highlights research and scientific advancements in Physical Medicine and Rehabilitation and related fields. #healthyaging #johnshopkins #sarcopenia #physicalactivity #exercisebenefits https://www.hopkinsmedicine.org/physical-medicine-rehabilitation/education-training/jeffrey-palmer-lectureship Lecture Details: Presenter: Walter R. Frontera, M.D., Ph.D., F.R.C.P. Date: October 14, 2025 Presentation Description: Life expectancy and the number of older adults have increased significantly over the last century. Aging is associated with a progressive loss of functional capacity and independence, with sarcopenia recognized as a major contributor to this decline. In this recorded lecture, Dr. Frontera reviews recent scientific advances that have deepened our understanding of sarcopenia and discusses evidence-based rehabilitation strategies aimed at improving function in affected individuals. https://www.youtube-nocookie.com/embed/BKrcFRb9n-E 3972 2025-10-31T13:50:07.000Z 2026-10-22T17:43:36.931Z https://longevityharbor.com/en/watch/BKvyR9ZqI5s AGING Speeds Up After 70 — But you Can Actually Reverse it | Here's What Science Says https://i.ytimg.com/vi/BKvyR9ZqI5s/hqdefault.jpg Aging changes after 70 — but does that mean your body has to decline rapidly? In this video, we explore what science says about aging after 70, why certain changes may accelerate, and which lifestyle habits may help support healthier aging. You’ll learn about the science behind aging, including muscle loss, brain health, heart health, sleep, nutrition, physical activity, and the everyday habits that may influence how well you age. In this video, we explore: • Why some aspects of aging may accelerate after 70 • What happens to muscle, strength, and mobility with age • How nutrition and physical activity support healthy aging • The connection between sleep, brain health, and aging • Habits that may help maintain independence and quality of life • What scientists mean when they discuss slowing or potentially reversing certain aspects of biological aging • Practical steps older adults can discuss with their healthcare professionals Getting older is inevitable — but the way we age can be influenced by many factors. Watch until the end to understand what current research actually says about healthy aging after 70. 🔔 **Subscribe for more science-informed videos about healthy aging, nutrition, heart health, brain health, sleep, and longevity.** **DISCLAIMER:** This video is for general educational and informational purposes only. It is not intended to provide medical advice, diagnosis, or treatment, and it does not guarantee that aging can be reversed. Individual health needs and responses vary. Always consult a qualified healthcare professional before making significant changes to your diet, exercise routine, medications, or treatment plan. #HealthyAging #AgingAfter70 #Longevity #HealthyAgingTips #AgingScience #SeniorHealth #BrainHealth #HeartHealth #Nutrition #HealthyLifestyle https://www.youtube-nocookie.com/embed/BKvyR9ZqI5s 1244 2026-09-26T22:07:43.000Z 2026-10-22T19:43:45.296Z https://longevityharbor.com/de/watch/BKvyR9ZqI5s AGING Speeds Up After 70 — But you Can Actually Reverse it | Here's What Science Says https://i.ytimg.com/vi/BKvyR9ZqI5s/hqdefault.jpg Aging changes after 70 — but does that mean your body has to decline rapidly? In this video, we explore what science says about aging after 70, why certain changes may accelerate, and which lifestyle habits may help support healthier aging. You’ll learn about the science behind aging, including muscle loss, brain health, heart health, sleep, nutrition, physical activity, and the everyday habits that may influence how well you age. In this video, we explore: • Why some aspects of aging may accelerate after 70 • What happens to muscle, strength, and mobility with age • How nutrition and physical activity support healthy aging • The connection between sleep, brain health, and aging • Habits that may help maintain independence and quality of life • What scientists mean when they discuss slowing or potentially reversing certain aspects of biological aging • Practical steps older adults can discuss with their healthcare professionals Getting older is inevitable — but the way we age can be influenced by many factors. Watch until the end to understand what current research actually says about healthy aging after 70. 🔔 **Subscribe for more science-informed videos about healthy aging, nutrition, heart health, brain health, sleep, and longevity.** **DISCLAIMER:** This video is for general educational and informational purposes only. It is not intended to provide medical advice, diagnosis, or treatment, and it does not guarantee that aging can be reversed. Individual health needs and responses vary. Always consult a qualified healthcare professional before making significant changes to your diet, exercise routine, medications, or treatment plan. #HealthyAging #AgingAfter70 #Longevity #HealthyAgingTips #AgingScience #SeniorHealth #BrainHealth #HeartHealth #Nutrition #HealthyLifestyle https://www.youtube-nocookie.com/embed/BKvyR9ZqI5s 1244 2026-09-26T22:07:43.000Z 2026-10-22T19:43:45.296Z https://longevityharbor.com/en/watch/BLw1eXerF-E Epigenetik: Wie kann ich meine Gene beeinflussen? | Quarks Dimension Ralph https://i.ytimg.com/vi/BLw1eXerF-E/hqdefault.jpg Ralph Caspers fragt sich, ob er seine Gene beeinflussen kann – und zwar epigenetisch! Und: ob dieser Einfluss vererbbar ist. Unsere Genetik können wir nicht verändern. Was sich aber das ganze Leben über ändert, ist die Epigenetik. Das sind verschiedene Mechanismen, die bestimmte Gen-Abschnitte lesbar oder unlesbar machen. In jeder einzelnen Zelle unseres Körpers ist ein zwei Meter langer DNA-Strang mit über 20.000 Genen. Doch längst nicht alle sind aktiv. Je nachdem, wie unsere DNA verpackt ist, gibt es Gene, die leichter zugänglich sind und Gene, die schwerer zugänglich sind. Die schwer zugänglichen Gene werden nicht mehr abgelesen – also regelrecht ausgeschaltet. Umwelteinflüsse wie unsere Ernährung können diese Vorgänge auslösen. Genau das ist Epigenetik. Sie verändert die Aktivität unserer Gene. Dabei sind manche dieser Veränderungen nur kurz. Andere bleiben uns sehr viel länger erhalten. Das ist ein Grund dafür, dass sich eineiige Zwillinge im Laufe ihres Lebens immer stärker unterscheiden. Für die Forschung stellt sich da die Frage: Wie soll man nachweisen, dass eine bestimmte Umwelt oder ein bestimmtes Verhalten einen Einfluss auf die Epigenetik hat? Man kann ja beim Menschen die Umweltbedingungen nicht so ohne weiteres kontrollieren. Im Video erzählt euch Ralph von einer Studie zur Frage, ob sportliches Training einen epigenetischen Einfluss hat – und wie die Wissenschaftler das Problem mit der Kontrolle der Umweltbedingungen gelöst haben. Wenn Epigenetik bestimmt, welche Gene aktiv sind, werden dann die epigenetischen Mechanismen auch vererbt? Diese Frage wird in der Wissenschaft heiß diskutiert. Eigentlich war man davon ausgegangen, dass epigenetische Veränderungen nicht vererbt werden. Im Video erzählt euch Ralph, warum das wohl _so_ nicht stimmt. *Kapitel* 0:00 Intro 0:57 Genetik, Gene und die DNA 3:31 Epigenetik: Gen-Abschnitte lesbar oder unlesbar machen 4:56 Was beeinflusst die Epigenetik? 6:27 Werden epigenetische Eigenschaften über die Gene vererbt? Autor:innen: Eva Schultes, Ralph C https://www.youtube-nocookie.com/embed/BLw1eXerF-E 524 2023-12-12T16:12:40.000Z 2026-10-22T17:11:30.658Z https://longevityharbor.com/de/watch/BLw1eXerF-E Epigenetik: Wie kann ich meine Gene beeinflussen? | Quarks Dimension Ralph https://i.ytimg.com/vi/BLw1eXerF-E/hqdefault.jpg Ralph Caspers fragt sich, ob er seine Gene beeinflussen kann – und zwar epigenetisch! Und: ob dieser Einfluss vererbbar ist. Unsere Genetik können wir nicht verändern. Was sich aber das ganze Leben über ändert, ist die Epigenetik. Das sind verschiedene Mechanismen, die bestimmte Gen-Abschnitte lesbar oder unlesbar machen. In jeder einzelnen Zelle unseres Körpers ist ein zwei Meter langer DNA-Strang mit über 20.000 Genen. Doch längst nicht alle sind aktiv. Je nachdem, wie unsere DNA verpackt ist, gibt es Gene, die leichter zugänglich sind und Gene, die schwerer zugänglich sind. Die schwer zugänglichen Gene werden nicht mehr abgelesen – also regelrecht ausgeschaltet. Umwelteinflüsse wie unsere Ernährung können diese Vorgänge auslösen. Genau das ist Epigenetik. Sie verändert die Aktivität unserer Gene. Dabei sind manche dieser Veränderungen nur kurz. Andere bleiben uns sehr viel länger erhalten. Das ist ein Grund dafür, dass sich eineiige Zwillinge im Laufe ihres Lebens immer stärker unterscheiden. Für die Forschung stellt sich da die Frage: Wie soll man nachweisen, dass eine bestimmte Umwelt oder ein bestimmtes Verhalten einen Einfluss auf die Epigenetik hat? Man kann ja beim Menschen die Umweltbedingungen nicht so ohne weiteres kontrollieren. Im Video erzählt euch Ralph von einer Studie zur Frage, ob sportliches Training einen epigenetischen Einfluss hat – und wie die Wissenschaftler das Problem mit der Kontrolle der Umweltbedingungen gelöst haben. Wenn Epigenetik bestimmt, welche Gene aktiv sind, werden dann die epigenetischen Mechanismen auch vererbt? Diese Frage wird in der Wissenschaft heiß diskutiert. Eigentlich war man davon ausgegangen, dass epigenetische Veränderungen nicht vererbt werden. Im Video erzählt euch Ralph, warum das wohl _so_ nicht stimmt. *Kapitel* 0:00 Intro 0:57 Genetik, Gene und die DNA 3:31 Epigenetik: Gen-Abschnitte lesbar oder unlesbar machen 4:56 Was beeinflusst die Epigenetik? 6:27 Werden epigenetische Eigenschaften über die Gene vererbt? Autor:innen: Eva Schultes, Ralph C https://www.youtube-nocookie.com/embed/BLw1eXerF-E 524 2023-12-12T16:12:40.000Z 2026-10-22T17:11:30.658Z https://longevityharbor.com/en/watch/BMS3nxfHkRM Video description: six daily habits for muscle strength after 60 https://i.ytimg.com/vi/BMS3nxfHkRM/hqdefault.jpg A video description from Senior Vitality lists six habits meant to support muscle health after 60: walking after meals, sleep, vitamin D, protein spread across the day, creatine with resistance training, and strength training. No study results are reported. https://www.youtube-nocookie.com/embed/BMS3nxfHkRM 1226 2026-10-21T20:00:17.000Z 2026-10-22T19:47:34.019Z https://longevityharbor.com/de/watch/BMS3nxfHkRM Videobeschreibung: sechs Alltagsgewohnheiten für Muskelkraft ab 60 https://i.ytimg.com/vi/BMS3nxfHkRM/hqdefault.jpg Eine Videobeschreibung von Senior Vitality nennt sechs Gewohnheiten für die Muskelgesundheit ab 60: Gehen nach Mahlzeiten, Schlaf, Vitamin D, über den Tag verteiltes Protein, Kreatin mit Krafttraining und Krafttraining. Studienergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/BMS3nxfHkRM 1226 2026-10-21T20:00:17.000Z 2026-10-22T19:47:34.019Z https://longevityharbor.com/en/watch/BNCocXSKOJo Rahbar Talk Show session 7: Role of Calorie Restriction and Intermittent Fasting in Human Health https://i.ytimg.com/vi/BNCocXSKOJo/hqdefault.jpg In this final session of our Calorie Restriction series, we dive deeper into the latest scientific findings behind CR and explore the key genes, pathways, and molecular mechanisms involved. We discuss how calorie restriction influences longevity-related pathways, such as mTOR, AMPK, SIRT1, and others, and review recent research on their roles in aging, metabolism, and cellular stress resistance. Whether you're studying aging biology, interested in metabolic health, or simply curious about the science behind calorie restriction, this session brings together the latest insights in a clear, accessible way. If you’ve been following this series, thank you for joining all the way to the final episode. Hashtags: #CalorieRestriction #Longevity #AgingResearch #Metabolism #AMPK #mTOR #Sirtuins #HealthScience #Biology #HealthyAging #Lifespan #CRResearch #CellularMechanisms #ScienceExplained https://www.youtube-nocookie.com/embed/BNCocXSKOJo 1666 2025-11-23T15:48:36.000Z 2026-10-22T18:32:09.972Z https://longevityharbor.com/de/watch/BNCocXSKOJo Rahbar Talk Show session 7: Role of Calorie Restriction and Intermittent Fasting in Human Health https://i.ytimg.com/vi/BNCocXSKOJo/hqdefault.jpg In this final session of our Calorie Restriction series, we dive deeper into the latest scientific findings behind CR and explore the key genes, pathways, and molecular mechanisms involved. We discuss how calorie restriction influences longevity-related pathways, such as mTOR, AMPK, SIRT1, and others, and review recent research on their roles in aging, metabolism, and cellular stress resistance. Whether you're studying aging biology, interested in metabolic health, or simply curious about the science behind calorie restriction, this session brings together the latest insights in a clear, accessible way. If you’ve been following this series, thank you for joining all the way to the final episode. Hashtags: #CalorieRestriction #Longevity #AgingResearch #Metabolism #AMPK #mTOR #Sirtuins #HealthScience #Biology #HealthyAging #Lifespan #CRResearch #CellularMechanisms #ScienceExplained https://www.youtube-nocookie.com/embed/BNCocXSKOJo 1666 2025-11-23T15:48:36.000Z 2026-10-22T18:32:09.972Z https://longevityharbor.com/en/watch/BPZBIzf39M0 Podcast description: exercise, nutrition and sleep for longevity https://i.ytimg.com/vi/BPZBIzf39M0/hqdefault.jpg The description says Dr. Rhonda Patrick discusses exercise intensity, the talk test, exercise snacks, visceral fat, sleep and diet habits for health and longevity. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/BPZBIzf39M0 5211 2026-06-25T09:00:33.000Z 2026-10-22T23:48:55.489Z https://longevityharbor.com/de/watch/BPZBIzf39M0 Podcast-Beschreibung: Bewegung, Ernährung und Schlaf für Langlebigkeit https://i.ytimg.com/vi/BPZBIzf39M0/hqdefault.jpg Laut Beschreibung spricht Dr. Rhonda Patrick über Trainingsintensität, den Sprechtest, kurze Bewegungsportionen, viszerales Fett, Schlaf und Essgewohnheiten für Gesundheit und Langlebigkeit. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/BPZBIzf39M0 5211 2026-06-25T09:00:33.000Z 2026-10-22T23:48:55.489Z https://longevityharbor.com/en/watch/BP_IJ3sbKQc Shock NAD results after 11-month NMN trial | What did it do for us and will we keep taking it? https://i.ytimg.com/vi/BP_IJ3sbKQc/hqdefault.jpg After taking the so-called longevity supplement NMN for 11 months, alongside my 80-year-old parents, I reveal our surprising test results! ⬇️ Click “…more” to see product links ⬇️ Plus I discuss the effects of NMN that we experienced, whether we intend to keep taking it long term and why. #longevity #nmn #healthyaging FEATURED PRODUCTS :: We use NMN from NMN BIO - there's a 10% discount on supplements here https://go.shopmy.us/p-23197219 with discount code HONEST All the supplements and health tools we use https://shopmy.us/shop/collections/408665 🛍️ Shop all my recommended skin and health products https://shopmy.us/TheHonestChannel I use affiliate links on this channel which means if you choose to buy a product using one of my links I receive a small commission - thank you! : ) WATCH 2025 UPDATE: My Parents' Healthy Aging Regimen in Their 80s (including why they still take NMN) https://youtu.be/PHV_VI1SKCg FOLLOW MY PARENTS' STRENGTH-BUILDING JOURNEY! Watch the 'Rebuilding Mum and Dad' series here and follow their progress https://www.youtube.com/playlist?list=PLwJwOmOzK8TBO3RfJC4LXOvzShe2ALNds ✅ Subscribe to my channel here https://www.youtube.com/thehonestchannel 🚨 Receive my FREE monthly newsletter https://mailchi.mp/honest/the-honest-channel-newsletter 📖 Read more advice and info around how to age well on my website https://www.honest.scot NMN now available for sale as a dietary supplement in the US again https://www.honest.scot/health-fitness/whats-the-deal-with-the-sale-of-nmn-in-the-us/ MY SKINCARE ROUTINE https://shopmy.us/collections/243245 On this link you'll find the products I use in my routine with discount codes where available. WATCH more on NMN Interview with Dr Elena re NMN benefits part 1: https://youtu.be/N0LDWTL2S1Q?si=x2FCrM8ion5LKd6F Part 2, with our early-stage experience of using NMN: https://youtu.be/Kry5bj1djiE?si=NdnwF82DrTO8b9S6 [Safety is discussed at 12.12] Dr Brad Stanfield interview: https://youtu.be/bDnw4qRVwqc?si=h6FlSRQFLZWCN6XQ This video is not sponsored. https://www.youtube-nocookie.com/embed/BP_IJ3sbKQc 909 2023-11-26T17:00:11.000Z 2026-10-22T18:43:09.871Z https://longevityharbor.com/de/watch/BP_IJ3sbKQc Shock NAD results after 11-month NMN trial | What did it do for us and will we keep taking it? https://i.ytimg.com/vi/BP_IJ3sbKQc/hqdefault.jpg After taking the so-called longevity supplement NMN for 11 months, alongside my 80-year-old parents, I reveal our surprising test results! ⬇️ Click “…more” to see product links ⬇️ Plus I discuss the effects of NMN that we experienced, whether we intend to keep taking it long term and why. #longevity #nmn #healthyaging FEATURED PRODUCTS :: We use NMN from NMN BIO - there's a 10% discount on supplements here https://go.shopmy.us/p-23197219 with discount code HONEST All the supplements and health tools we use https://shopmy.us/shop/collections/408665 🛍️ Shop all my recommended skin and health products https://shopmy.us/TheHonestChannel I use affiliate links on this channel which means if you choose to buy a product using one of my links I receive a small commission - thank you! : ) WATCH 2025 UPDATE: My Parents' Healthy Aging Regimen in Their 80s (including why they still take NMN) https://youtu.be/PHV_VI1SKCg FOLLOW MY PARENTS' STRENGTH-BUILDING JOURNEY! Watch the 'Rebuilding Mum and Dad' series here and follow their progress https://www.youtube.com/playlist?list=PLwJwOmOzK8TBO3RfJC4LXOvzShe2ALNds ✅ Subscribe to my channel here https://www.youtube.com/thehonestchannel 🚨 Receive my FREE monthly newsletter https://mailchi.mp/honest/the-honest-channel-newsletter 📖 Read more advice and info around how to age well on my website https://www.honest.scot NMN now available for sale as a dietary supplement in the US again https://www.honest.scot/health-fitness/whats-the-deal-with-the-sale-of-nmn-in-the-us/ MY SKINCARE ROUTINE https://shopmy.us/collections/243245 On this link you'll find the products I use in my routine with discount codes where available. WATCH more on NMN Interview with Dr Elena re NMN benefits part 1: https://youtu.be/N0LDWTL2S1Q?si=x2FCrM8ion5LKd6F Part 2, with our early-stage experience of using NMN: https://youtu.be/Kry5bj1djiE?si=NdnwF82DrTO8b9S6 [Safety is discussed at 12.12] Dr Brad Stanfield interview: https://youtu.be/bDnw4qRVwqc?si=h6FlSRQFLZWCN6XQ This video is not sponsored. https://www.youtube-nocookie.com/embed/BP_IJ3sbKQc 909 2023-11-26T17:00:11.000Z 2026-10-22T18:43:09.871Z https://longevityharbor.com/en/watch/BVEOpslNymg Mitochondrial Health: Nutrition Tips from Dr. William Li https://i.ytimg.com/vi/BVEOpslNymg/hqdefault.jpg 📖 Download my FREE 5 Foods to Boost Your Metabolism resource HERE: https://news.drwilliamli.com/c/5foodstoboostmetabolism 🫐 Learn more about my Eat to Beat Disease Course: https://eat-to-beat-disease.teachable.com/ 👉 Subscribe for more science-backed insights on food and longevity! Boost your energy, improve metabolism, and unlock the secrets to healthy aging -- in this video, Dr. William Li dives deep into mitochondrial health and shares simple, science-backed strategies to keep these "cellular batteries" performing at their best. From green tea and dark chocolate to intermittent fasting and movement tips, learn practical ways to power up your body and mind. Whether you're looking to shed stubborn fat, reduce cravings, or extend your healthspan, this video provides actionable advice grounded in research. 🔑 Key Topics Covered: - What are mitochondria, and why are they vital for energy and longevity? - How green tea activates brown fat and promotes weight loss. - The surprising link between intermittent fasting and efficient mitochondria. - Dark chocolate, beans, and healthy fats: nutritional powerhouses for cellular health. - Simple movement tips to combat the effects of sedentary behavior. - Foods and habits to reduce oxidative stress and protect your mitochondria. Grab a copy of "Eat To Beat Disease" - https://amzn.to/3Rh9RAe #EatToBeatDisease #EatToBeatYourDiet #MitochondrialHealth #DrWilliamLi #IntermittentFasting #GreenTeaBenefits #HealthyAging https://www.youtube-nocookie.com/embed/BVEOpslNymg 3055 2025-01-24T10:30:10.000Z 2026-10-22T19:43:45.486Z https://longevityharbor.com/de/watch/BVEOpslNymg Mitochondrial Health: Nutrition Tips from Dr. William Li https://i.ytimg.com/vi/BVEOpslNymg/hqdefault.jpg 📖 Download my FREE 5 Foods to Boost Your Metabolism resource HERE: https://news.drwilliamli.com/c/5foodstoboostmetabolism 🫐 Learn more about my Eat to Beat Disease Course: https://eat-to-beat-disease.teachable.com/ 👉 Subscribe for more science-backed insights on food and longevity! Boost your energy, improve metabolism, and unlock the secrets to healthy aging -- in this video, Dr. William Li dives deep into mitochondrial health and shares simple, science-backed strategies to keep these "cellular batteries" performing at their best. From green tea and dark chocolate to intermittent fasting and movement tips, learn practical ways to power up your body and mind. Whether you're looking to shed stubborn fat, reduce cravings, or extend your healthspan, this video provides actionable advice grounded in research. 🔑 Key Topics Covered: - What are mitochondria, and why are they vital for energy and longevity? - How green tea activates brown fat and promotes weight loss. - The surprising link between intermittent fasting and efficient mitochondria. - Dark chocolate, beans, and healthy fats: nutritional powerhouses for cellular health. - Simple movement tips to combat the effects of sedentary behavior. - Foods and habits to reduce oxidative stress and protect your mitochondria. Grab a copy of "Eat To Beat Disease" - https://amzn.to/3Rh9RAe #EatToBeatDisease #EatToBeatYourDiet #MitochondrialHealth #DrWilliamLi #IntermittentFasting #GreenTeaBenefits #HealthyAging https://www.youtube-nocookie.com/embed/BVEOpslNymg 3055 2025-01-24T10:30:10.000Z 2026-10-22T19:43:45.486Z https://longevityharbor.com/en/watch/BVHhnNeuLZ0 Caloric Restriction and Its Effects on Cellular Aging Mechanisms https://i.ytimg.com/vi/BVHhnNeuLZ0/hqdefault.jpg 🔥 #CellularAging #CaloricRestriction #Longevity Have you ever wondered how eating fewer calories—without sacrificing essential nutrition—might influence the aging process? In this video, we explore the fascinating science behind **caloric restriction** and its impact on **cellular aging mechanisms**. Learn how reducing calorie intake may activate natural repair systems, improve metabolic health, reduce oxidative stress, enhance autophagy, and support healthy longevity. We'll break down complex biological concepts into easy-to-understand explanations, covering how caloric restriction affects mitochondria, inflammation, DNA repair, and longevity-related pathways. Whether you're interested in anti-aging research, metabolic health, or evidence-based wellness, this video provides valuable insights backed by modern scientific understanding. ✔️ Understand the science of cellular aging in simple terms. ✔️ Learn how caloric restriction influences longevity pathways. ✔️ Discover the role of autophagy and mitochondrial health. ✔️ Explore potential health benefits supported by research. ✔️ Separate scientific facts from common myths. ✔️ Gain practical knowledge for a healthier lifestyle. 👍 If you enjoyed this video, don't forget to **Like, Share, Subscribe**, and turn on the notification bell to stay updated with more evidence-based videos on health, metabolism, nutrition, longevity, and wellness. #CellularAging, #CaloricRestriction, #Longevity, #HealthyAging, #AntiAging, #MetabolicHealth, #Autophagy, #NutritionScience, #Wellness, #HealthEducation, #Mitochondria, #DNARepair, #OxidativeStress, #Inflammation, #HealthyLifestyle, #BodyAndMind, #Biohacking, #AgingResearch, #IntermittentFasting, #LifeExtension, #CellHealth, #Metabolism, #HealthTips, #ScienceExplained, #LongevityResearch, #FitnessHealth, #Nutrition, #PreventiveHealth, #MedicalScience, #HealthChannel caloric restriction, cellular aging, longevity, anti aging, autophagy, healthy aging, metabolism, metabolic health, oxidative stress, DNA repair, mitochondria, https://www.youtube-nocookie.com/embed/BVHhnNeuLZ0 526 2026-07-02T18:00:09.000Z 2026-10-22T18:54:08.046Z https://longevityharbor.com/de/watch/BVHhnNeuLZ0 Caloric Restriction and Its Effects on Cellular Aging Mechanisms https://i.ytimg.com/vi/BVHhnNeuLZ0/hqdefault.jpg 🔥 #CellularAging #CaloricRestriction #Longevity Have you ever wondered how eating fewer calories—without sacrificing essential nutrition—might influence the aging process? In this video, we explore the fascinating science behind **caloric restriction** and its impact on **cellular aging mechanisms**. Learn how reducing calorie intake may activate natural repair systems, improve metabolic health, reduce oxidative stress, enhance autophagy, and support healthy longevity. We'll break down complex biological concepts into easy-to-understand explanations, covering how caloric restriction affects mitochondria, inflammation, DNA repair, and longevity-related pathways. Whether you're interested in anti-aging research, metabolic health, or evidence-based wellness, this video provides valuable insights backed by modern scientific understanding. ✔️ Understand the science of cellular aging in simple terms. ✔️ Learn how caloric restriction influences longevity pathways. ✔️ Discover the role of autophagy and mitochondrial health. ✔️ Explore potential health benefits supported by research. ✔️ Separate scientific facts from common myths. ✔️ Gain practical knowledge for a healthier lifestyle. 👍 If you enjoyed this video, don't forget to **Like, Share, Subscribe**, and turn on the notification bell to stay updated with more evidence-based videos on health, metabolism, nutrition, longevity, and wellness. #CellularAging, #CaloricRestriction, #Longevity, #HealthyAging, #AntiAging, #MetabolicHealth, #Autophagy, #NutritionScience, #Wellness, #HealthEducation, #Mitochondria, #DNARepair, #OxidativeStress, #Inflammation, #HealthyLifestyle, #BodyAndMind, #Biohacking, #AgingResearch, #IntermittentFasting, #LifeExtension, #CellHealth, #Metabolism, #HealthTips, #ScienceExplained, #LongevityResearch, #FitnessHealth, #Nutrition, #PreventiveHealth, #MedicalScience, #HealthChannel caloric restriction, cellular aging, longevity, anti aging, autophagy, healthy aging, metabolism, metabolic health, oxidative stress, DNA repair, mitochondria, https://www.youtube-nocookie.com/embed/BVHhnNeuLZ0 526 2026-07-02T18:00:09.000Z 2026-10-22T18:54:08.046Z https://longevityharbor.com/en/watch/BVgeoJdRhfk Hallmarks of Ageing: Focus on Iron Deregulation and Ageing | Prof Christiaan Leeuwenburgh https://i.ytimg.com/vi/BVgeoJdRhfk/hqdefault.jpg In this #webinar, Prof Christiaan Leeuwenburgh from the Department of Physiology and Ageing in University of Florida, United States, spoke about iron deregulation and ageing. His research focus is on understanding the molecular mechanisms of mitochondrial dysfunction, iron transport deregulation, autophagy and oxidative damage to Mt DNA in advanced age in animal models and humans. Register for upcoming #HealthyLongevity #webinar sessions at https://bit.ly/3F0IlRd #NUSMedicine #webinarseries Closing video source: https://www.youtube.com/watch?v=y7q0ftQ-19o Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. https://www.youtube-nocookie.com/embed/BVgeoJdRhfk 3864 2024-05-17T02:25:28.000Z 2026-10-22T19:32:33.170Z https://longevityharbor.com/de/watch/BVgeoJdRhfk Hallmarks of Ageing: Focus on Iron Deregulation and Ageing | Prof Christiaan Leeuwenburgh https://i.ytimg.com/vi/BVgeoJdRhfk/hqdefault.jpg In this #webinar, Prof Christiaan Leeuwenburgh from the Department of Physiology and Ageing in University of Florida, United States, spoke about iron deregulation and ageing. His research focus is on understanding the molecular mechanisms of mitochondrial dysfunction, iron transport deregulation, autophagy and oxidative damage to Mt DNA in advanced age in animal models and humans. Register for upcoming #HealthyLongevity #webinar sessions at https://bit.ly/3F0IlRd #NUSMedicine #webinarseries Closing video source: https://www.youtube.com/watch?v=y7q0ftQ-19o Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. https://www.youtube-nocookie.com/embed/BVgeoJdRhfk 3864 2024-05-17T02:25:28.000Z 2026-10-22T19:32:33.170Z https://longevityharbor.com/en/watch/BWe30-E4gq8 Video description: OMAD fat burning, fat loss and autophagy claims checked https://i.ytimg.com/vi/BWe30-E4gq8/hqdefault.jpg The description says one small, short crossover study in lean adults found more fat oxidation during exercise and a larger short-term drop in body and fat mass with one evening meal, but it cannot show the fasting window caused superior fat loss. https://www.youtube-nocookie.com/embed/BWe30-E4gq8 458 2026-07-26T18:01:33.000Z 2026-10-22T23:22:21.132Z https://longevityharbor.com/de/watch/BWe30-E4gq8 Videobeschreibung: OMAD-Fettverbrennung, Fettverlust und Autophagie-Behauptungen geprüft https://i.ytimg.com/vi/BWe30-E4gq8/hqdefault.jpg Laut Beschreibung fand eine kleine, kurze Crossover-Studie an schlanken Erwachsenen mehr Fettoxidation beim Training und einen größeren kurzfristigen Rückgang von Körper- und Fettmasse bei einer Abendmahlzeit; sie kann aber nicht belegen, dass das Fastenfenster einen überlegenen Fettverlust verursachte. https://www.youtube-nocookie.com/embed/BWe30-E4gq8 458 2026-07-26T18:01:33.000Z 2026-10-22T23:22:21.132Z https://longevityharbor.com/en/watch/B_CqKVU19ec The science of super longevity | Dr. Morgan Levine https://i.ytimg.com/vi/B_CqKVU19ec/hqdefault.jpg Become a Big Think member to unlock expert classes, premium print issues, exclusive events and more: https://bigthink.com/membership/?utm_source=youtube&utm_medium=social&utm_campaign=yt_desc Science can’t stop aging, but it may be able to slow our epigenetic clocks. Subscribe to Big Think on YouTube ► https://www.youtube.com/channel/UCvQECJukTDE2i6aCoMnS-Vg?sub_confirmation=1 Up next, Michio Kaku: How to reverse aging ► https://www.youtube.com/watch?v=DV3XjqW_xgU What if we could slow down the hands of our biological clocks? This question underpins much of the research of Morgan Levine, who leads a research team at the life science company Altos Labs. Levine investigates the fascinating intricacies of aging, recognizing that it doesn't happen at a uniform pace for everyone. Central to her exploration is the concept of epigenetics — the factors that influence gene activity without changing the DNA sequence. Levine focuses on DNA methylation, a significant epigenetic change that occurs with aging, and the development of models called "epigenetic clocks" that can be used to predict biological age. While she acknowledges that it might be possible to reverse aging at a cellular level, Levine clarifies that the ultimate goal is not to "cure" aging or death, but to delay disease onset and improve healthspan. 0:00 Fast agers & slow agers 1:25 The hallmarks of aging 1:59 What is the epigenetic clock? 3:05 Can we ‘Benjamin Button’ aging? 5:22 The holy grail for scientists Read the video transcript ► https://bigthink.com/series/explain-it-like-im-smart/epigenetics-and-aging/?utm_source=youtube&utm_medium=video&utm_campaign=youtube_description ---------------------------------------------------------------------------------- About Morgan Levine: Morgan Levine was previously a tenure-track Assistant Professor in the department of Pathology at Yale University where she ran the Laboratory for Aging in Living Systems. In 2022, she was recruited to join Altos Labs as a Founding Principal Investigator at the San Diego https://www.youtube-nocookie.com/embed/B_CqKVU19ec 435 2023-05-26T13:00:07.000Z 2026-10-22T17:43:39.285Z https://longevityharbor.com/de/watch/B_CqKVU19ec The science of super longevity | Dr. Morgan Levine https://i.ytimg.com/vi/B_CqKVU19ec/hqdefault.jpg Become a Big Think member to unlock expert classes, premium print issues, exclusive events and more: https://bigthink.com/membership/?utm_source=youtube&utm_medium=social&utm_campaign=yt_desc Science can’t stop aging, but it may be able to slow our epigenetic clocks. Subscribe to Big Think on YouTube ► https://www.youtube.com/channel/UCvQECJukTDE2i6aCoMnS-Vg?sub_confirmation=1 Up next, Michio Kaku: How to reverse aging ► https://www.youtube.com/watch?v=DV3XjqW_xgU What if we could slow down the hands of our biological clocks? This question underpins much of the research of Morgan Levine, who leads a research team at the life science company Altos Labs. Levine investigates the fascinating intricacies of aging, recognizing that it doesn't happen at a uniform pace for everyone. Central to her exploration is the concept of epigenetics — the factors that influence gene activity without changing the DNA sequence. Levine focuses on DNA methylation, a significant epigenetic change that occurs with aging, and the development of models called "epigenetic clocks" that can be used to predict biological age. While she acknowledges that it might be possible to reverse aging at a cellular level, Levine clarifies that the ultimate goal is not to "cure" aging or death, but to delay disease onset and improve healthspan. 0:00 Fast agers & slow agers 1:25 The hallmarks of aging 1:59 What is the epigenetic clock? 3:05 Can we ‘Benjamin Button’ aging? 5:22 The holy grail for scientists Read the video transcript ► https://bigthink.com/series/explain-it-like-im-smart/epigenetics-and-aging/?utm_source=youtube&utm_medium=video&utm_campaign=youtube_description ---------------------------------------------------------------------------------- About Morgan Levine: Morgan Levine was previously a tenure-track Assistant Professor in the department of Pathology at Yale University where she ran the Laboratory for Aging in Living Systems. In 2022, she was recruited to join Altos Labs as a Founding Principal Investigator at the San Diego https://www.youtube-nocookie.com/embed/B_CqKVU19ec 435 2023-05-26T13:00:07.000Z 2026-10-22T17:43:39.285Z https://longevityharbor.com/en/watch/BcT2xYDuE1g Fasting Mimicking Diet, longevity and age-related diseases | Valter Longo, PhD | The Metabolic Link https://i.ytimg.com/vi/BcT2xYDuE1g/hqdefault.jpg Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.com In this episode of The Metabolic Link filmed at Metabolic Health Summit 2024, Dr. Valter Longo shares his latest research on the fasting mimicking diet (FMD) and its powerful impact on aging, metabolic diseases, and cancer treatment. With a focus on periodic fasting interventions, Dr. Longo highlights the role of FMD in activating stem cells, enhancing cellular repair mechanisms, and even reversing metabolic dysfunctions like insulin resistance and type 1 diabetes. Dr. Longo’s work is paving the way for more accessible, non-invasive therapies for chronic conditions, with far-reaching implications for aging, cancer prevention, and metabolic health. If you’re an academic, medical professional, or researcher, you won’t want to miss this in-depth discussion on how FMD could shape the future of medicine. Valter Longo, PhD, is the Edna Jones Professor in Gerontology, the Director of the USC Longevity Institute and group leader at the IFOM cancer research institute in Milan, Italy. His laboratories study the fundamental mechanisms of aging in yeast, rodents and humans by using genetics and biochemistry techniques. The focus is on the nutrient-response signal transduction pathways that regulate disease and longevity. This work led to the discovery of the effects of periodic fasting and fasting mimicking diets on multi-system stem cell activation and regeneration in mice, and to clinical trials on a range of age-related diseases. Special thanks to the sponsors of this episode: Genova Connect: Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclink AG1: This November, AG1 is offering a free gift with your first subscription plus a Welcome Kit at https://DrinkAG1.com/METABOLICLINK—while supplies last! Ned: Get 15% o https://www.youtube-nocookie.com/embed/BcT2xYDuE1g 4588 2024-11-26T17:14:53.000Z 2026-10-22T19:32:32.089Z https://longevityharbor.com/de/watch/BcT2xYDuE1g Fasting Mimicking Diet, longevity and age-related diseases | Valter Longo, PhD | The Metabolic Link https://i.ytimg.com/vi/BcT2xYDuE1g/hqdefault.jpg Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.com In this episode of The Metabolic Link filmed at Metabolic Health Summit 2024, Dr. Valter Longo shares his latest research on the fasting mimicking diet (FMD) and its powerful impact on aging, metabolic diseases, and cancer treatment. With a focus on periodic fasting interventions, Dr. Longo highlights the role of FMD in activating stem cells, enhancing cellular repair mechanisms, and even reversing metabolic dysfunctions like insulin resistance and type 1 diabetes. Dr. Longo’s work is paving the way for more accessible, non-invasive therapies for chronic conditions, with far-reaching implications for aging, cancer prevention, and metabolic health. If you’re an academic, medical professional, or researcher, you won’t want to miss this in-depth discussion on how FMD could shape the future of medicine. Valter Longo, PhD, is the Edna Jones Professor in Gerontology, the Director of the USC Longevity Institute and group leader at the IFOM cancer research institute in Milan, Italy. His laboratories study the fundamental mechanisms of aging in yeast, rodents and humans by using genetics and biochemistry techniques. The focus is on the nutrient-response signal transduction pathways that regulate disease and longevity. This work led to the discovery of the effects of periodic fasting and fasting mimicking diets on multi-system stem cell activation and regeneration in mice, and to clinical trials on a range of age-related diseases. Special thanks to the sponsors of this episode: Genova Connect: Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclink AG1: This November, AG1 is offering a free gift with your first subscription plus a Welcome Kit at https://DrinkAG1.com/METABOLICLINK—while supplies last! Ned: Get 15% o https://www.youtube-nocookie.com/embed/BcT2xYDuE1g 4588 2024-11-26T17:14:53.000Z 2026-10-22T19:32:32.089Z https://longevityharbor.com/en/watch/Bco0au4S3UM Rapamycin and the mTOR Pathway | WP-53 https://i.ytimg.com/vi/Bco0au4S3UM/hqdefault.jpg Rapamycin and the mTOR Pathway | WP-53 https://www.youtube-nocookie.com/embed/Bco0au4S3UM 194 2026-04-28T22:07:09.000Z 2026-10-22T19:54:22.213Z https://longevityharbor.com/de/watch/Bco0au4S3UM Rapamycin and the mTOR Pathway | WP-53 https://i.ytimg.com/vi/Bco0au4S3UM/hqdefault.jpg Rapamycin and the mTOR Pathway | WP-53 https://www.youtube-nocookie.com/embed/Bco0au4S3UM 194 2026-04-28T22:07:09.000Z 2026-10-22T19:54:22.213Z https://longevityharbor.com/en/watch/Bdid6-uVZ6A Video description: biological vs chronological age and proposed longevity topics https://i.ytimg.com/vi/Bdid6-uVZ6A/hqdefault.jpg The description presents a talk by Dr. Datis Kharrazian contrasting chronological and biological age, citing a 16,566-person longevity study and the 12 Hallmarks of Aging, and promotes a paid Longevity Mastery Program. These are creator claims in the description only. https://www.youtube-nocookie.com/embed/Bdid6-uVZ6A 658 2025-12-24T21:14:03.000Z 2026-10-23T03:13:44.791Z https://longevityharbor.com/de/watch/Bdid6-uVZ6A Videobeschreibung: biologisches vs. chronologisches Alter und vorgeschlagene Langlebigkeitsthemen https://i.ytimg.com/vi/Bdid6-uVZ6A/hqdefault.jpg Die Beschreibung stellt einen Vortrag von Dr. Datis Kharrazian gegenüber, der chronologisches und biologisches Alter kontrastiert, eine Langlebigkeitsstudie mit 16.566 Personen und die 12 Hallmarks of Aging nennt und ein kostenpflichtiges Longevity Mastery Program bewirbt. Dies sind nur Aussagen des Erstellers in der Beschreibung. https://www.youtube-nocookie.com/embed/Bdid6-uVZ6A 658 2025-12-24T21:14:03.000Z 2026-10-23T03:13:44.791Z https://longevityharbor.com/en/watch/Bh68VtqBJYs Stanford podcast description: strength training, interval training and exercise in midlife https://i.ytimg.com/vi/Bh68VtqBJYs/hqdefault.jpg The description says Stanford experts discuss strength training, interval training, motivation and a balanced exercise plan for healthy aging in midlife; the video itself was not reviewed. https://www.youtube-nocookie.com/embed/Bh68VtqBJYs 1649 2026-08-04T21:00:17.000Z 2026-10-22T23:15:16.654Z https://longevityharbor.com/de/watch/Bh68VtqBJYs Stanford-Podcast-Beschreibung: Krafttraining, Intervalltraining und Bewegung in der Lebensmitte https://i.ytimg.com/vi/Bh68VtqBJYs/hqdefault.jpg Laut Beschreibung besprechen Stanford-Fachleute Krafttraining, Intervalltraining, Motivation und einen ausgewogenen Trainingsplan für gesundes Altern in der Lebensmitte; das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/Bh68VtqBJYs 1649 2026-08-04T21:00:17.000Z 2026-10-22T23:15:16.654Z https://longevityharbor.com/en/watch/BlOR9ghaVDI What Time Should The Elderly Go to Bed After 70 For Better Health — Here's What Doctors Explain! https://i.ytimg.com/vi/BlOR9ghaVDI/hqdefault.jpg What Time Should The Elderly Go to Bed After 70 For Better Health — Here's What Doctors Explain! Are you sleeping 7 or 8 hours every night and still waking up exhausted, foggy, and dragging through the day? For older adults, the issue often isn’t how long you sleep—it’s when you sleep. As we age past 70, the brain’s master internal clock undergoes circadian phase advancement, shifting our optimal window for deep, restorative slow-wave sleep much earlier into the evening. Staying up until 11:00 PM means missing critical restorative sleep, the heart’s nocturnal blood pressure dip, and the brain’s glymphatic waste-clearance cycle. In this video, Dr. Jasper breaks down: Why the traditional 8-hour rule fails after age 70 The exact biological bedtime window supported by sleep research 4 warning signs your current schedule is working against your health How medications like beta blockers and ACE inhibitors interact with sleep The glymphatic system and its connection to brain health and memory A step-by-step action plan to recalibrate your internal clock gradually Timestamps: 00:00 - The 8-Hour Sleep Myth After 70 02:23 - Circadian Phase Advancement & Your Internal Clock 04:37 - The Optimal Bedtime Window (9:00 PM – 10:00 PM) 05:09 - 4 Warning Signs Your Bedtime Is Working Against You 06:44 - Patient Case Study: Eleanor's Sleep Shift 07:22 - Cardiovascular Health & The Nocturnal Dip 08:18 - Medication Alerts: Beta Blockers & ACE Inhibitors 09:33 - The Glymphatic System: Brain Cleaning & Cognitive Health 12:15 - When to Seek Clinical Evaluation (Sleep Apnea & Symptoms) 13:04 - Action Plan: How to Shift Your Bedtime Safely 14:17 - The Power of Morning Light & Consistent Wake Times 15:39 - Evening Meal Timing & Nighttime Routine 16:11 - 4 Key Questions to Ask Your Doctor 17:23 - Supplements & Sleep Aids: Melatonin, Magnesium & Alcohol 18:40 - Summary & Key Takeaways Tags sleep after 70, best bedtime for seniors, elderly sleep patterns, senior health, circadian rhythm aging, slow wave deep sleep, insomnia in seniors, https://www.youtube-nocookie.com/embed/BlOR9ghaVDI 1245 2026-10-20T15:00:27.000Z 2026-10-22T19:21:25.204Z https://longevityharbor.com/de/watch/BlOR9ghaVDI What Time Should The Elderly Go to Bed After 70 For Better Health — Here's What Doctors Explain! https://i.ytimg.com/vi/BlOR9ghaVDI/hqdefault.jpg What Time Should The Elderly Go to Bed After 70 For Better Health — Here's What Doctors Explain! Are you sleeping 7 or 8 hours every night and still waking up exhausted, foggy, and dragging through the day? For older adults, the issue often isn’t how long you sleep—it’s when you sleep. As we age past 70, the brain’s master internal clock undergoes circadian phase advancement, shifting our optimal window for deep, restorative slow-wave sleep much earlier into the evening. Staying up until 11:00 PM means missing critical restorative sleep, the heart’s nocturnal blood pressure dip, and the brain’s glymphatic waste-clearance cycle. In this video, Dr. Jasper breaks down: Why the traditional 8-hour rule fails after age 70 The exact biological bedtime window supported by sleep research 4 warning signs your current schedule is working against your health How medications like beta blockers and ACE inhibitors interact with sleep The glymphatic system and its connection to brain health and memory A step-by-step action plan to recalibrate your internal clock gradually Timestamps: 00:00 - The 8-Hour Sleep Myth After 70 02:23 - Circadian Phase Advancement & Your Internal Clock 04:37 - The Optimal Bedtime Window (9:00 PM – 10:00 PM) 05:09 - 4 Warning Signs Your Bedtime Is Working Against You 06:44 - Patient Case Study: Eleanor's Sleep Shift 07:22 - Cardiovascular Health & The Nocturnal Dip 08:18 - Medication Alerts: Beta Blockers & ACE Inhibitors 09:33 - The Glymphatic System: Brain Cleaning & Cognitive Health 12:15 - When to Seek Clinical Evaluation (Sleep Apnea & Symptoms) 13:04 - Action Plan: How to Shift Your Bedtime Safely 14:17 - The Power of Morning Light & Consistent Wake Times 15:39 - Evening Meal Timing & Nighttime Routine 16:11 - 4 Key Questions to Ask Your Doctor 17:23 - Supplements & Sleep Aids: Melatonin, Magnesium & Alcohol 18:40 - Summary & Key Takeaways Tags sleep after 70, best bedtime for seniors, elderly sleep patterns, senior health, circadian rhythm aging, slow wave deep sleep, insomnia in seniors, https://www.youtube-nocookie.com/embed/BlOR9ghaVDI 1245 2026-10-20T15:00:27.000Z 2026-10-22T19:21:25.204Z https://longevityharbor.com/en/watch/BoSpdxcYcLQ Epigenetic aging clocks tested: responsiveness across 51 intervention studies https://i.ytimg.com/vi/BoSpdxcYcLQ/hqdefault.jpg A Nature Medicine analysis of 51 intervention studies and 3,128 blood samples found next-generation clocks, especially DunedinPACE and PCGrimAge, most responsive; a clock moving backward does not yet prove longer or healthier life. https://www.youtube-nocookie.com/embed/BoSpdxcYcLQ 134 2026-08-22T09:05:07.000Z 2026-10-22T22:49:25.626Z https://longevityharbor.com/de/watch/BoSpdxcYcLQ Epigenetische Altersuhren im Test: Reaktion in 51 Interventionsstudien https://i.ytimg.com/vi/BoSpdxcYcLQ/hqdefault.jpg Eine Nature-Medicine-Analyse von 51 Interventionsstudien und 3.128 Blutproben fand, dass Uhren der nächsten Generation, besonders DunedinPACE und PCGrimAge, am stärksten reagierten; eine rückwärts laufende Uhr beweist noch kein längeres oder gesünderes Leben. https://www.youtube-nocookie.com/embed/BoSpdxcYcLQ 134 2026-08-22T09:05:07.000Z 2026-10-22T22:49:25.626Z https://longevityharbor.com/en/watch/Bq5vmjqfS7k 🥗🧬💊 “Eat Less or Pop a Pill? Rapamycin vs. Metformin https://i.ytimg.com/vi/Bq5vmjqfS7k/hqdefault.jpg 🔬 New meta-analysis alert! 🧪 Researchers compared rapamycin and metformin to dietary restriction across 167 studies in 8 vertebrate species. 📈 Key finding: Rapamycin mirrors dietary restriction’s longevity benefits—but metformin falls short. ⚠️ High heterogeneity and species bias remind us: translation to human health still needs careful navigation. 🧠 Full of insights for aging science, pharmacology, and precision medicine! #LongevityScience #Rapamycin #AgingResearch #MetaAnalysis #LifespanExtension #PrecisionMedicine 👩‍🔬📊🧬 https://www.youtube-nocookie.com/embed/Bq5vmjqfS7k 228 2025-06-21T09:04:24.000Z 2026-10-22T18:43:08.065Z https://longevityharbor.com/de/watch/Bq5vmjqfS7k 🥗🧬💊 “Eat Less or Pop a Pill? Rapamycin vs. Metformin https://i.ytimg.com/vi/Bq5vmjqfS7k/hqdefault.jpg 🔬 New meta-analysis alert! 🧪 Researchers compared rapamycin and metformin to dietary restriction across 167 studies in 8 vertebrate species. 📈 Key finding: Rapamycin mirrors dietary restriction’s longevity benefits—but metformin falls short. ⚠️ High heterogeneity and species bias remind us: translation to human health still needs careful navigation. 🧠 Full of insights for aging science, pharmacology, and precision medicine! #LongevityScience #Rapamycin #AgingResearch #MetaAnalysis #LifespanExtension #PrecisionMedicine 👩‍🔬📊🧬 https://www.youtube-nocookie.com/embed/Bq5vmjqfS7k 228 2025-06-21T09:04:24.000Z 2026-10-22T18:43:08.065Z https://longevityharbor.com/en/watch/Br_-Dipc9Hc The Bortz Biological Age Clock: Better Than PhenoAge? https://i.ytimg.com/vi/Br_-Dipc9Hc/hqdefault.jpg Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD Discount Links/Affiliates: Blood testing (where I get the majority of my labs, for those who blood test with Quest): https://www.ultalabtests.com/partners/conqueragingordietrying Blood Testing Essentials (Biological Age, CVD-Risk, Kidney Health and Function): PhenoAge (Biological Age): https://www.ultalabtests.com/partners/conqueragingordietrying/test/conquer-aging-or-die-trying-what-s-my-biological-age-phenoage-test Risk-weighted ApoB (a better CVD predictor than LDL, non-HDL cholesterol, and ApoB): https://www.ultalabtests.com/partners/conqueragingordietrying/test/conquer-aging-or-die-trying-risk-weighted-apo-b Kidney health and function: https://www.ultalabtests.com/partners/conqueragingordietrying/test/conquer-aging-or-die-trying-kidney-health-and-function For those who blood test with LabCorp: https://www.anrdoezrs.net/click-101614996-15750394 At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten Use Code: CONQUERAGING At Checkout Clearly Filtered Water Filter: https://get.aspr.app/SHoPY Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ62UkAVXBWtRVKJUM0&irgwc=1 Use Code: CONQUERAGING NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/ Use Code: ConquerAging At Checkout Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten Enter Code: ConquerAging SiphoxHealth Blood Testing (ApoB, GrimAge): https://siphoxhealth.com/mlustgarten Green Tea: https://www.ochaandco.com/?ref=fqbtflod Use Code: ML10OFF Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack= If you'd like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/ Measure the Bortz biological clock biomarkers: https://www.ultalabtests.com/partners/conqueragingordietrying/test/conquer-aging-or-die-trying-bortz-biological-a https://www.youtube-nocookie.com/embed/Br_-Dipc9Hc 5061 2026-05-31T08:30:03.000Z 2026-10-22T18:32:06.751Z https://longevityharbor.com/de/watch/Br_-Dipc9Hc The Bortz Biological Age Clock: Better Than PhenoAge? https://i.ytimg.com/vi/Br_-Dipc9Hc/hqdefault.jpg Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD Discount Links/Affiliates: Blood testing (where I get the majority of my labs, for those who blood test with Quest): https://www.ultalabtests.com/partners/conqueragingordietrying Blood Testing Essentials (Biological Age, CVD-Risk, Kidney Health and Function): PhenoAge (Biological Age): https://www.ultalabtests.com/partners/conqueragingordietrying/test/conquer-aging-or-die-trying-what-s-my-biological-age-phenoage-test Risk-weighted ApoB (a better CVD predictor than LDL, non-HDL cholesterol, and ApoB): https://www.ultalabtests.com/partners/conqueragingordietrying/test/conquer-aging-or-die-trying-risk-weighted-apo-b Kidney health and function: https://www.ultalabtests.com/partners/conqueragingordietrying/test/conquer-aging-or-die-trying-kidney-health-and-function For those who blood test with LabCorp: https://www.anrdoezrs.net/click-101614996-15750394 At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten Use Code: CONQUERAGING At Checkout Clearly Filtered Water Filter: https://get.aspr.app/SHoPY Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ62UkAVXBWtRVKJUM0&irgwc=1 Use Code: CONQUERAGING NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/ Use Code: ConquerAging At Checkout Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten Enter Code: ConquerAging SiphoxHealth Blood Testing (ApoB, GrimAge): https://siphoxhealth.com/mlustgarten Green Tea: https://www.ochaandco.com/?ref=fqbtflod Use Code: ML10OFF Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack= If you'd like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/ Measure the Bortz biological clock biomarkers: https://www.ultalabtests.com/partners/conqueragingordietrying/test/conquer-aging-or-die-trying-bortz-biological-a https://www.youtube-nocookie.com/embed/Br_-Dipc9Hc 5061 2026-05-31T08:30:03.000Z 2026-10-22T18:32:06.751Z https://longevityharbor.com/en/watch/BtioZEiA9sY Caloric Restriction and Intermittent Fasting: Do They Really Extend Lifespan? https://i.ytimg.com/vi/BtioZEiA9sY/hqdefault.jpg This video explores the findings of a groundbreaking study published in Nature, which examined the effects of caloric restriction (CR) and intermittent fasting (IF) on the lifespan and health of mice. ● The study followed nearly 1,000 genetically diverse mice across their lifespans, subjecting them to varying degrees of CR and IF. ● Both CR and IF extended lifespan, but the extent of the benefit depended on the degree of restriction. ● Surprisingly, metabolic improvements like reduced adiposity and lower fasting glucose were not associated with increased lifespan, suggesting that DR does more than just counteract the negative effects of obesity. ● The study also revealed a paradox: while DR extends lifespan and decreases body weight and fat mass, preserving body weight and fat mass is associated with longer lifespan. ● Genetic factors played a larger role in determining lifespan than dietary interventions. ● Researchers identified a specific genetic variant associated with both lifespan and red blood cell distribution width (RDW), a marker linked to aging and disease. ● These findings suggest that the effects of DR are highly individualized and dependent on genetic background. ● The study raises questions about the most relevant endpoints for evaluating aging interventions in humans. This video will discuss the implications of these findings for human health and longevity, and explore the potential benefits and drawbacks of CR and IF. 🔍 Source: Di Francesco A., Deighan A.G., Litichevskiy L. et al. Dietary restriction impacts health and lifespan of genetically diverse mice. Nature (2024). https://doi.org/10.1038/s41586-024-08026-3 ⚠️ Disclaimer: This podcast is generated by an artificial intelligence. While we strive to provide accurate and up-to-date information, please note that the content is created by an AI and may not always reflect the most current research or developments. These videos are intended for entertainment purposes, focusing on scientific topics and technological innovations. We encourage list https://www.youtube-nocookie.com/embed/BtioZEiA9sY 929 2024-11-29T22:00:12.000Z 2026-10-22T18:32:09.999Z https://longevityharbor.com/de/watch/BtioZEiA9sY Caloric Restriction and Intermittent Fasting: Do They Really Extend Lifespan? https://i.ytimg.com/vi/BtioZEiA9sY/hqdefault.jpg This video explores the findings of a groundbreaking study published in Nature, which examined the effects of caloric restriction (CR) and intermittent fasting (IF) on the lifespan and health of mice. ● The study followed nearly 1,000 genetically diverse mice across their lifespans, subjecting them to varying degrees of CR and IF. ● Both CR and IF extended lifespan, but the extent of the benefit depended on the degree of restriction. ● Surprisingly, metabolic improvements like reduced adiposity and lower fasting glucose were not associated with increased lifespan, suggesting that DR does more than just counteract the negative effects of obesity. ● The study also revealed a paradox: while DR extends lifespan and decreases body weight and fat mass, preserving body weight and fat mass is associated with longer lifespan. ● Genetic factors played a larger role in determining lifespan than dietary interventions. ● Researchers identified a specific genetic variant associated with both lifespan and red blood cell distribution width (RDW), a marker linked to aging and disease. ● These findings suggest that the effects of DR are highly individualized and dependent on genetic background. ● The study raises questions about the most relevant endpoints for evaluating aging interventions in humans. This video will discuss the implications of these findings for human health and longevity, and explore the potential benefits and drawbacks of CR and IF. 🔍 Source: Di Francesco A., Deighan A.G., Litichevskiy L. et al. Dietary restriction impacts health and lifespan of genetically diverse mice. Nature (2024). https://doi.org/10.1038/s41586-024-08026-3 ⚠️ Disclaimer: This podcast is generated by an artificial intelligence. While we strive to provide accurate and up-to-date information, please note that the content is created by an AI and may not always reflect the most current research or developments. These videos are intended for entertainment purposes, focusing on scientific topics and technological innovations. We encourage list https://www.youtube-nocookie.com/embed/BtioZEiA9sY 929 2024-11-29T22:00:12.000Z 2026-10-22T18:32:09.999Z https://longevityharbor.com/en/watch/BtmfadAjcpI Cellular Senescence and Senolytics in Aging and Diseases https://i.ytimg.com/vi/BtmfadAjcpI/hqdefault.jpg Join us for a BioTalk webinar on cellular senescence, a hallmark of aging where cells permanently exit the cell cycle due to damage and stress. Cellular senescence, a hallmark of aging, involves the stable exit from the cell cycle in response to cellular damage and stress. Senescent cells (SnCs) often develop a pathogenic senescence-associated secretory phenotype (SASP) that promotes secondary senescence and disrupts tissue homeostasis, impairing tissue repair and regeneration. Transgenic mouse models with the capability for genetic ablation of SnCs have demonstrated their crucial role in driving aging and related diseases. Consequently, senotherapeutics have been developed to either pharmacologically eliminate SnCs (senolytics) or suppress the SASP and other senescence markers (senomorphics). Extensive preclinical studies and initial clinical trials have shown the potential benefits of senotherapeutics, leading to multiple ongoing clinical trials. In conclusion, targeting cellular senescence presents a promising therapeutic strategy for slowing aging and treating age-related diseases. This webinar is made by GenoBioTX in clollaboration with SinoBiogical. About GenoBioTX GenoBioTX, a US branch of Shanghai Model Organisms Center Inc, provides comprehensive animal modeling services, ranging from model construction to preclinical in vitro and in vivo assays, based on the combination of versatile technical platforms and experienced scientist. https://www.youtube-nocookie.com/embed/BtmfadAjcpI 3278 2024-09-25T20:01:42.000Z 2026-10-23T02:56:02.546Z https://longevityharbor.com/de/watch/BtmfadAjcpI Cellular Senescence and Senolytics in Aging and Diseases https://i.ytimg.com/vi/BtmfadAjcpI/hqdefault.jpg Join us for a BioTalk webinar on cellular senescence, a hallmark of aging where cells permanently exit the cell cycle due to damage and stress. Cellular senescence, a hallmark of aging, involves the stable exit from the cell cycle in response to cellular damage and stress. Senescent cells (SnCs) often develop a pathogenic senescence-associated secretory phenotype (SASP) that promotes secondary senescence and disrupts tissue homeostasis, impairing tissue repair and regeneration. Transgenic mouse models with the capability for genetic ablation of SnCs have demonstrated their crucial role in driving aging and related diseases. Consequently, senotherapeutics have been developed to either pharmacologically eliminate SnCs (senolytics) or suppress the SASP and other senescence markers (senomorphics). Extensive preclinical studies and initial clinical trials have shown the potential benefits of senotherapeutics, leading to multiple ongoing clinical trials. In conclusion, targeting cellular senescence presents a promising therapeutic strategy for slowing aging and treating age-related diseases. This webinar is made by GenoBioTX in clollaboration with SinoBiogical. About GenoBioTX GenoBioTX, a US branch of Shanghai Model Organisms Center Inc, provides comprehensive animal modeling services, ranging from model construction to preclinical in vitro and in vivo assays, based on the combination of versatile technical platforms and experienced scientist. https://www.youtube-nocookie.com/embed/BtmfadAjcpI 3278 2024-09-25T20:01:42.000Z 2026-10-23T02:56:02.546Z https://longevityharbor.com/en/watch/BwvSG5VpVaA Top 5 Supplements to Add YEARS to Your Life (Lifespan Extension Supplements) https://i.ytimg.com/vi/BwvSG5VpVaA/hqdefault.jpg 💊 Want to live longer and slow down aging? These are the Top 5 Supplements for Lifespan Extension backed by cutting-edge longevity research. In this video, I break down the best anti-aging supplements that target the root causes of aging—not just symptoms. These compounds are known as geroprotective agents, meaning they act on the 12 Hallmarks of Aging to extend lifespan and healthspan. If you’ve already watched my Top 5 Foundational Supplements for Longevity & Performance videos, this is your next step. Whether you want to live longer, feel younger, or slow biological aging, these are the most powerful longevity supplements to add to your stack. As a medical doctor (MD) and certified strength and conditioning coach, I’ll guide you through: ✅ The science behind each supplement and how it works to slow aging ✅ The best form, brand, and dose based on clinical evidence ✅ The right timing for real anti-aging, mitochondrial, and cellular benefits 🚀 Top 5 Supplements to Live Longer & Slow Aging (2025 Update) 1️⃣ Taurine – Boosts mitochondrial function, reduces oxidative stress, and increases lifespan by up to 25% in mice. (Best for energy, heart health, and aging mitochondria.) 2️⃣ Spermidine – Activates autophagy (cellular cleanup), decreases 9 hallmarks of aging, and supports healthy longevity. (Best anti-aging supplement for cell renewal.) 3️⃣ Green Tea Extract (EGCG) – Improves metabolism, reduces inflammation, and enhances mitochondrial resilience. (Best natural supplement for lifespan extension and longevity.) 4️⃣ Astaxanthin – Ultra-potent antioxidant (6,000x stronger than Vitamin C) that supports brain, skin, and heart health while extending lifespan in male mice. (Top antioxidant for aging and oxidative stress.) 5️⃣ Glycine (+ NAC) – Mimics methionine restriction, boosts glutathione, and extends lifespan in NIH Interventions Testing Program studies. (Best amino acid supplement for longevity and healthy aging.) 🔥 Timestamps 00:00 The 2 Types of Longevity Supplements - Intro to the Hallmarks of A https://www.youtube-nocookie.com/embed/BwvSG5VpVaA 3158 2025-10-17T17:00:14.000Z 2026-10-22T19:54:19.375Z https://longevityharbor.com/de/watch/BwvSG5VpVaA Top 5 Supplements to Add YEARS to Your Life (Lifespan Extension Supplements) https://i.ytimg.com/vi/BwvSG5VpVaA/hqdefault.jpg 💊 Want to live longer and slow down aging? These are the Top 5 Supplements for Lifespan Extension backed by cutting-edge longevity research. In this video, I break down the best anti-aging supplements that target the root causes of aging—not just symptoms. These compounds are known as geroprotective agents, meaning they act on the 12 Hallmarks of Aging to extend lifespan and healthspan. If you’ve already watched my Top 5 Foundational Supplements for Longevity & Performance videos, this is your next step. Whether you want to live longer, feel younger, or slow biological aging, these are the most powerful longevity supplements to add to your stack. As a medical doctor (MD) and certified strength and conditioning coach, I’ll guide you through: ✅ The science behind each supplement and how it works to slow aging ✅ The best form, brand, and dose based on clinical evidence ✅ The right timing for real anti-aging, mitochondrial, and cellular benefits 🚀 Top 5 Supplements to Live Longer & Slow Aging (2025 Update) 1️⃣ Taurine – Boosts mitochondrial function, reduces oxidative stress, and increases lifespan by up to 25% in mice. (Best for energy, heart health, and aging mitochondria.) 2️⃣ Spermidine – Activates autophagy (cellular cleanup), decreases 9 hallmarks of aging, and supports healthy longevity. (Best anti-aging supplement for cell renewal.) 3️⃣ Green Tea Extract (EGCG) – Improves metabolism, reduces inflammation, and enhances mitochondrial resilience. (Best natural supplement for lifespan extension and longevity.) 4️⃣ Astaxanthin – Ultra-potent antioxidant (6,000x stronger than Vitamin C) that supports brain, skin, and heart health while extending lifespan in male mice. (Top antioxidant for aging and oxidative stress.) 5️⃣ Glycine (+ NAC) – Mimics methionine restriction, boosts glutathione, and extends lifespan in NIH Interventions Testing Program studies. (Best amino acid supplement for longevity and healthy aging.) 🔥 Timestamps 00:00 The 2 Types of Longevity Supplements - Intro to the Hallmarks of A https://www.youtube-nocookie.com/embed/BwvSG5VpVaA 3158 2025-10-17T17:00:14.000Z 2026-10-22T19:54:19.375Z https://longevityharbor.com/en/watch/BzpaQ0F49JE Protein, Metabolism & Aging: Nutrition Tips for Longevity https://i.ytimg.com/vi/BzpaQ0F49JE/hqdefault.jpg Eating well is important as we age, but with so much conflicting diet advice, how do you know what’s truly best for older adults? In this episode, geriatrician Leslie Kernisan, MD MPH, clears up common misconceptions about senior nutrition and breaks down the key components of a diet that supports healthy aging and metabolic health. Learn why nutrition science isn’t one-size-fits-all, how metabolism changes with age, and why maintaining muscle mass is crucial for long-term health. Dr. Kernisan also explains the role of protein, how to prevent malnutrition, and what older adults can do to reduce frailty and stay strong. Plus, what to know about vitamins and supplements for healthier aging, and which ones she recommends. If you or a loved one are wondering how to eat for better energy, strength, and longevity, this discussion provides practical, science-backed advice tailored for aging adults. Click here for more resources: https://betterhealthwhileaging.net/podcast/diet-and-nutrition-for-healthy-aging/ Related article: What to Do About Unintentional Weight Loss: https://betterhealthwhileaging.net/qa-unintentional-weight-loss-in-aging/ #nutritionforaging, #healthyeating, #agingwell, #malnutrition, #proteinforaging, #sarcopenia, #betterhealthwhileaging Chapters: 00:00 Introduction to Nutrition and Aging 02:19 What to know about nutrition science 09:11 My view of a nutritious diet 12:50 How to eat healthy in aging 20:29 What is metabolic health 23:33 How to check your own metabolic health 25:41 How to improve metabolic health 31:15 Malnutrition in aging 34:07 How nutrition helps with frailty and sarcopenia 37:52 Protein intake in aging 40:10 Vitamins and supplements in aging 42:58 Dr. K’s approach to diet and aging 43:31 Conclusion and key takeaways WATCH NEXT: Exercise and Aging https://youtu.be/jbVT7GSDsEs?si=l5yOjm4yinMBJ9PI How to Improve Brain Health in Aging https://youtu.be/xKr9RTmXY1s The Surprising Risks of Too Much Vitamin D for Seniors https://youtu.be/YIvY8wyjfE4 3 Keys To Aging Successfully ht https://www.youtube-nocookie.com/embed/BzpaQ0F49JE 2732 2025-02-10T18:56:46.000Z 2026-10-22T18:43:11.668Z https://longevityharbor.com/de/watch/BzpaQ0F49JE Protein, Metabolism & Aging: Nutrition Tips for Longevity https://i.ytimg.com/vi/BzpaQ0F49JE/hqdefault.jpg Eating well is important as we age, but with so much conflicting diet advice, how do you know what’s truly best for older adults? In this episode, geriatrician Leslie Kernisan, MD MPH, clears up common misconceptions about senior nutrition and breaks down the key components of a diet that supports healthy aging and metabolic health. Learn why nutrition science isn’t one-size-fits-all, how metabolism changes with age, and why maintaining muscle mass is crucial for long-term health. Dr. Kernisan also explains the role of protein, how to prevent malnutrition, and what older adults can do to reduce frailty and stay strong. Plus, what to know about vitamins and supplements for healthier aging, and which ones she recommends. If you or a loved one are wondering how to eat for better energy, strength, and longevity, this discussion provides practical, science-backed advice tailored for aging adults. Click here for more resources: https://betterhealthwhileaging.net/podcast/diet-and-nutrition-for-healthy-aging/ Related article: What to Do About Unintentional Weight Loss: https://betterhealthwhileaging.net/qa-unintentional-weight-loss-in-aging/ #nutritionforaging, #healthyeating, #agingwell, #malnutrition, #proteinforaging, #sarcopenia, #betterhealthwhileaging Chapters: 00:00 Introduction to Nutrition and Aging 02:19 What to know about nutrition science 09:11 My view of a nutritious diet 12:50 How to eat healthy in aging 20:29 What is metabolic health 23:33 How to check your own metabolic health 25:41 How to improve metabolic health 31:15 Malnutrition in aging 34:07 How nutrition helps with frailty and sarcopenia 37:52 Protein intake in aging 40:10 Vitamins and supplements in aging 42:58 Dr. K’s approach to diet and aging 43:31 Conclusion and key takeaways WATCH NEXT: Exercise and Aging https://youtu.be/jbVT7GSDsEs?si=l5yOjm4yinMBJ9PI How to Improve Brain Health in Aging https://youtu.be/xKr9RTmXY1s The Surprising Risks of Too Much Vitamin D for Seniors https://youtu.be/YIvY8wyjfE4 3 Keys To Aging Successfully ht https://www.youtube-nocookie.com/embed/BzpaQ0F49JE 2732 2025-02-10T18:56:46.000Z 2026-10-22T18:43:11.668Z https://longevityharbor.com/en/watch/C08YxJrLHFU Wasserfasten: Das passiert, wenn du 7 Tage nichts isst https://i.ytimg.com/vi/C08YxJrLHFU/hqdefault.jpg Achtung: Bitte konsultiert immer euren Arzt, bevor ihr Fasten ausprobiert! Wasserfasten ist eine sehr extreme Form des Fastens - dabei könnten dem Körper Elektrolyte wie Natrium, Kalium, Magnesium fehlen (!), die ihr ggf. zuführen müsstet. Wenn man zu viel Wasser trinkt (oder ausschließlich Wasser), könnte der Elektrolythaushalt gestört werden, was gefährliche gesundheitliche Folgen haben kann. Also bitte unbedingt mit eurem Arzt sprechen, bevor ihr fastet. Erst recht, wenn ihr gesundheitliche Beschwerden habt. Fasten kann unser Leben verlängern, reinigt unsere Zellen und verjüngt uns biologisch. Und wenn Harvard-Genetiker und Altersforscher David Sinclair nur einen Rat geben könnte, wie man sein Leben verlängern kann, dann wäre es: Fasten! Warum genau, was Autophagie und Ketose damit zu tun haben und wie man richtig fastet? Das erfahrt ihr in diesem Video! #Fasten #Wasserfasten #Heilfasten Disclaimer: Wenn ihr Metformin oder andere Medikamente einnehmt, konsultiert unbedingt euren Arzt, bevor ihr Wasserfasten in Erwägung zieht. Metformin und mehrere Tage Fasten geht nicht zusammen, soweit ich weiss. Ich bin kein Arzt und gebe hier keine medizinischen Ratschläge. Bitte sprecht unbedingt mit eurem Arzt, bevor ihr in Erwägung zieht, die hier besprochenen Wege, Mittel und Supplements auszuprobieren. Werbung: Die nachfolgenden Produkt-Links sind Affiliate Links (*): Wenn du über diese Links etwas kaufst, erhalte ich eine kleine Vergütung, für dich entstehen dabei keinerlei Mehrkosten. Du kannst natürlich die Sachen auch woanders kaufen, ganz wie du magst. Danke, dass du meinen Kanal unterstützt. :) 💊Supplements, die ich nehme, um Altern aufzuhalten - auf alles 15% Rabatt mit dem Code "ANASTASIA":💊 * NMN: in EU hergestelltes Longevir NMN: https://avea-life.com/de/products/nmn?aff=ANASTASIARASTOR (1 Kapsel morgens mit Wasser) * Mein Longevity Bundle / alle Longevity-Wirkstoffe in einem Bundle: NMN, TMG, Trans-Resveratrol, Coenzym Q10, Pterostilben, Apigenin, Kollagen: https://avea-life.com/de/products/longe https://www.youtube-nocookie.com/embed/C08YxJrLHFU 724 2020-06-28T14:53:33.000Z 2026-10-22T17:43:37.717Z https://longevityharbor.com/de/watch/C08YxJrLHFU Wasserfasten: Das passiert, wenn du 7 Tage nichts isst https://i.ytimg.com/vi/C08YxJrLHFU/hqdefault.jpg Achtung: Bitte konsultiert immer euren Arzt, bevor ihr Fasten ausprobiert! Wasserfasten ist eine sehr extreme Form des Fastens - dabei könnten dem Körper Elektrolyte wie Natrium, Kalium, Magnesium fehlen (!), die ihr ggf. zuführen müsstet. Wenn man zu viel Wasser trinkt (oder ausschließlich Wasser), könnte der Elektrolythaushalt gestört werden, was gefährliche gesundheitliche Folgen haben kann. Also bitte unbedingt mit eurem Arzt sprechen, bevor ihr fastet. Erst recht, wenn ihr gesundheitliche Beschwerden habt. Fasten kann unser Leben verlängern, reinigt unsere Zellen und verjüngt uns biologisch. Und wenn Harvard-Genetiker und Altersforscher David Sinclair nur einen Rat geben könnte, wie man sein Leben verlängern kann, dann wäre es: Fasten! Warum genau, was Autophagie und Ketose damit zu tun haben und wie man richtig fastet? Das erfahrt ihr in diesem Video! #Fasten #Wasserfasten #Heilfasten Disclaimer: Wenn ihr Metformin oder andere Medikamente einnehmt, konsultiert unbedingt euren Arzt, bevor ihr Wasserfasten in Erwägung zieht. Metformin und mehrere Tage Fasten geht nicht zusammen, soweit ich weiss. Ich bin kein Arzt und gebe hier keine medizinischen Ratschläge. Bitte sprecht unbedingt mit eurem Arzt, bevor ihr in Erwägung zieht, die hier besprochenen Wege, Mittel und Supplements auszuprobieren. Werbung: Die nachfolgenden Produkt-Links sind Affiliate Links (*): Wenn du über diese Links etwas kaufst, erhalte ich eine kleine Vergütung, für dich entstehen dabei keinerlei Mehrkosten. Du kannst natürlich die Sachen auch woanders kaufen, ganz wie du magst. Danke, dass du meinen Kanal unterstützt. :) 💊Supplements, die ich nehme, um Altern aufzuhalten - auf alles 15% Rabatt mit dem Code "ANASTASIA":💊 * NMN: in EU hergestelltes Longevir NMN: https://avea-life.com/de/products/nmn?aff=ANASTASIARASTOR (1 Kapsel morgens mit Wasser) * Mein Longevity Bundle / alle Longevity-Wirkstoffe in einem Bundle: NMN, TMG, Trans-Resveratrol, Coenzym Q10, Pterostilben, Apigenin, Kollagen: https://avea-life.com/de/products/longe https://www.youtube-nocookie.com/embed/C08YxJrLHFU 724 2020-06-28T14:53:33.000Z 2026-10-22T17:43:37.717Z https://longevityharbor.com/en/watch/C25IfCm3nzA Rapamycin and mTOR: Creator's Description of Slowed Aging https://i.ytimg.com/vi/C25IfCm3nzA/hqdefault.jpg The description says rapamycin targets the mTOR protein, slows aging and boosts stress resistance, acting as a cellular decision-maker between growth and survival. It gives no species, study or human outcome details. https://www.youtube-nocookie.com/embed/C25IfCm3nzA 90 2026-10-04T16:04:38.000Z 2026-10-22T21:23:23.522Z https://longevityharbor.com/de/watch/C25IfCm3nzA Rapamycin und mTOR: Beschreibung verlangsamter Alterung https://i.ytimg.com/vi/C25IfCm3nzA/hqdefault.jpg Die Beschreibung sagt, Rapamycin wirke auf das Protein mTOR, verlangsame die Alterung und stärke die Stresstoleranz; es wirke als zellulärer Entscheider zwischen Wachstum und Überleben. Arten, Studien oder menschliche Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/C25IfCm3nzA 90 2026-10-04T16:04:38.000Z 2026-10-22T21:23:23.522Z https://longevityharbor.com/en/watch/C2L6OsgYPu0 NMN or astaxanthin — which one should you actually be taking? https://i.ytimg.com/vi/C2L6OsgYPu0/hqdefault.jpg Please SUBSCRIBE for new videos about health and hormones Let's connect on... Tik tok: Faithfuldoc IG: faithful_doc FB: faithful doc Twitter: Faithful doc Website: https://faithfuldoc.com Contact email: support@faithfuldoc.com ** The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/health professional ** https://www.youtube-nocookie.com/embed/C2L6OsgYPu0 125 2026-08-09T21:19:24.000Z 2026-10-22T19:32:37.480Z https://longevityharbor.com/de/watch/C2L6OsgYPu0 NMN or astaxanthin — which one should you actually be taking? https://i.ytimg.com/vi/C2L6OsgYPu0/hqdefault.jpg Please SUBSCRIBE for new videos about health and hormones Let's connect on... Tik tok: Faithfuldoc IG: faithful_doc FB: faithful doc Twitter: Faithful doc Website: https://faithfuldoc.com Contact email: support@faithfuldoc.com ** The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/health professional ** https://www.youtube-nocookie.com/embed/C2L6OsgYPu0 125 2026-08-09T21:19:24.000Z 2026-10-22T19:32:37.480Z https://longevityharbor.com/en/watch/C8gWWgxddaE Video description: epigenetic clocks as biological age measures https://i.ytimg.com/vi/C8gWWgxddaE/hqdefault.jpg The description says epigenetic clocks are established as robust measures of chronological age and outperform telomere length as an age predictor. It links to further videos, a book and a presentation; the video itself was not reviewed. https://www.youtube-nocookie.com/embed/C8gWWgxddaE 357 2026-08-28T11:59:48.000Z 2026-10-22T22:40:05.908Z https://longevityharbor.com/de/watch/C8gWWgxddaE Videobeschreibung: epigenetische Uhren als Maße des biologischen Alters https://i.ytimg.com/vi/C8gWWgxddaE/hqdefault.jpg Laut Beschreibung gelten epigenetische Uhren als robuste Maße des chronologischen Alters und übertreffen die Telomerlänge als Altersprädiktor. Sie verweist auf weitere Videos, ein Buch und eine Präsentation; das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/C8gWWgxddaE 357 2026-08-28T11:59:48.000Z 2026-10-22T22:40:05.908Z https://longevityharbor.com/en/watch/CCaUu8-sjDw Video description: two home exercises for strength after 60 https://i.ytimg.com/vi/CCaUu8-sjDw/hqdefault.jpg A video description aimed at people over 60 says age-related muscle loss can affect strength, balance and daily tasks, and that two home exercises using body weight, a chair or a wall may support muscle strength. No results, numbers or study are reported. https://www.youtube-nocookie.com/embed/CCaUu8-sjDw 1327 2026-10-18T10:15:19.000Z 2026-10-22T19:52:10.338Z https://longevityharbor.com/de/watch/CCaUu8-sjDw Videobeschreibung: zwei Übungen zu Hause für Kraft ab 60 https://i.ytimg.com/vi/CCaUu8-sjDw/hqdefault.jpg Eine Videobeschreibung für Menschen über 60 sagt, altersbezogener Muskelverlust könne Kraft, Gleichgewicht und Alltagsaufgaben beeinflussen, und zwei Übungen zu Hause mit Körpergewicht, Stuhl oder Wand könnten die Muskelkraft unterstützen. Ergebnisse, Zahlen oder eine Studie werden nicht berichtet. https://www.youtube-nocookie.com/embed/CCaUu8-sjDw 1327 2026-10-18T10:15:19.000Z 2026-10-22T19:52:10.338Z https://longevityharbor.com/en/watch/CCsjTicjZYM Video description claims topical rapamycin makes old skin cells act young https://i.ytimg.com/vi/CCsjTicjZYM/hqdefault.jpg The description says a topical RapaLog resets the mTOR cycle so 50-year-old fibroblasts look and function like 20-year-old cells; it attributes this to Kay Durairaj MD and names no study. https://www.youtube-nocookie.com/embed/CCsjTicjZYM 93 2026-10-04T14:30:17.000Z 2026-10-22T21:26:21.694Z https://longevityharbor.com/de/watch/CCsjTicjZYM Videobeschreibung behauptet, topisches Rapamycin lasse alte Hautzellen jung wirken https://i.ytimg.com/vi/CCsjTicjZYM/hqdefault.jpg Die Beschreibung sagt, ein topisches RapaLog setze den mTOR-Zyklus zurück, sodass 50 Jahre alte Fibroblasten aussehen und funktionieren wie 20 Jahre alte Zellen; sie schreibt dies Kay Durairaj MD zu und nennt keine Studie. https://www.youtube-nocookie.com/embed/CCsjTicjZYM 93 2026-10-04T14:30:17.000Z 2026-10-22T21:26:21.694Z https://longevityharbor.com/en/watch/CJDT3JCP3gM Video explains NAD+, NMN, NR and niacinamide with a bakery analogy https://i.ytimg.com/vi/CJDT3JCP3gM/hqdefault.jpg The creator says marketing makes NAD+, NMN, NR and niacinamide sound interchangeable, and uses a bakery analogy to explain that they are not the same. https://www.youtube-nocookie.com/embed/CJDT3JCP3gM 100 2026-07-10T16:32:14.000Z 2026-10-22T23:35:29.600Z https://longevityharbor.com/de/watch/CJDT3JCP3gM Video erklärt NAD+, NMN, NR und Niacinamid mit einer Bäckerei-Analogie https://i.ytimg.com/vi/CJDT3JCP3gM/hqdefault.jpg Der Ersteller sagt, Marketing lasse NAD+, NMN, NR und Niacinamid austauschbar klingen, und nutzt eine Bäckerei-Analogie, um zu erklären, dass sie nicht gleich sind. https://www.youtube-nocookie.com/embed/CJDT3JCP3gM 100 2026-07-10T16:32:14.000Z 2026-10-22T23:35:29.600Z https://longevityharbor.com/en/watch/CKiEElFaWV4 Podcast description: Plant-based diets and healthy aging in older adults https://i.ytimg.com/vi/CKiEElFaWV4/hqdefault.jpg A podcast description announces a conversation with dietitian Brenda Davis about her book on plant-based nutrition for older adults, covering protein and muscle, bone health, omega-3 fats, brain function and common myths. No study results are reported. https://www.youtube-nocookie.com/embed/CKiEElFaWV4 4239 2026-10-21T23:00:20.000Z 2026-10-22T19:47:23.967Z https://longevityharbor.com/de/watch/CKiEElFaWV4 Podcast-Beschreibung: Pflanzliche Ernährung und gesundes Altern bei älteren Menschen https://i.ytimg.com/vi/CKiEElFaWV4/hqdefault.jpg Eine Podcast-Beschreibung kündigt ein Gespräch mit der Ernährungsberaterin Brenda Davis über ihr Buch zur pflanzlichen Ernährung älterer Menschen an: Protein und Muskeln, Knochengesundheit, Omega-3-Fette, Gehirnfunktion und verbreitete Mythen. Studienergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/CKiEElFaWV4 4239 2026-10-21T23:00:20.000Z 2026-10-22T19:47:23.967Z https://longevityharbor.com/en/watch/CMritOkxzUE Autophagie Aktivieren für Ein Längeres Leben: Japanische Geheimnisse für Gesundheit https://i.ytimg.com/vi/CMritOkxzUE/hqdefault.jpg Autophagie Aktivieren für Ein Längeres Leben: Japanische Geheimnisse für Gesundheit Description: Autophagie und Langlebigkeit: Erfahren Sie, wie japanische Ärzte ein gesundes, langes Leben fördern. In diesem Video zeigen wir, wie Intervallfasten, “Hara Hachi Bu” und nährstoffreiche Lebensmittel die Zellreinigung ankurbeln und Krankheiten vorbeugen. Wir stellen Erkenntnisse des Nobelpreisträgers Dr. Yoshinori Osumi und weiterer japanischer Experten vor, die helfen, schlank, jung und energiegeladen zu bleiben. Abonnieren Sie unseren Kanal für mehr Gesundheitstipps und teilen Sie dieses Video, wenn Sie ein längeres, erfülltes Leben anstreben. Keywords: autophagie, langlebigkeit, intervallfasten, hara hachi bu, zellreinigung, japanische medizin, dr yoshinori osumi, gesunde lebensweise, japanische diät, bewusste ernährung, gesundes altern, prävention, japanische ärzte, vitalität, ganzheitliche gesundheit Hashtags: [#Autophagie, #Langlebigkeit, #Intervallfasten, #HaraHachiBu, #JapanischeMedizin, #GesundesAltern, #GesundeErnährung, #Zellreinigung, #DrOsumi, #Lebensstil, #Prävention, #Vitalität, #Gewichtskontrolle, #GanzheitlicheGesundheit, #Lebensfreude] https://www.youtube-nocookie.com/embed/CMritOkxzUE 1288 2025-04-05T18:00:09.000Z 2026-10-22T19:54:16.785Z https://longevityharbor.com/de/watch/CMritOkxzUE Autophagie Aktivieren für Ein Längeres Leben: Japanische Geheimnisse für Gesundheit https://i.ytimg.com/vi/CMritOkxzUE/hqdefault.jpg Autophagie Aktivieren für Ein Längeres Leben: Japanische Geheimnisse für Gesundheit Description: Autophagie und Langlebigkeit: Erfahren Sie, wie japanische Ärzte ein gesundes, langes Leben fördern. In diesem Video zeigen wir, wie Intervallfasten, “Hara Hachi Bu” und nährstoffreiche Lebensmittel die Zellreinigung ankurbeln und Krankheiten vorbeugen. Wir stellen Erkenntnisse des Nobelpreisträgers Dr. Yoshinori Osumi und weiterer japanischer Experten vor, die helfen, schlank, jung und energiegeladen zu bleiben. Abonnieren Sie unseren Kanal für mehr Gesundheitstipps und teilen Sie dieses Video, wenn Sie ein längeres, erfülltes Leben anstreben. Keywords: autophagie, langlebigkeit, intervallfasten, hara hachi bu, zellreinigung, japanische medizin, dr yoshinori osumi, gesunde lebensweise, japanische diät, bewusste ernährung, gesundes altern, prävention, japanische ärzte, vitalität, ganzheitliche gesundheit Hashtags: [#Autophagie, #Langlebigkeit, #Intervallfasten, #HaraHachiBu, #JapanischeMedizin, #GesundesAltern, #GesundeErnährung, #Zellreinigung, #DrOsumi, #Lebensstil, #Prävention, #Vitalität, #Gewichtskontrolle, #GanzheitlicheGesundheit, #Lebensfreude] https://www.youtube-nocookie.com/embed/CMritOkxzUE 1288 2025-04-05T18:00:09.000Z 2026-10-22T19:54:16.785Z https://longevityharbor.com/en/watch/CPpkKbZebmk Review links lower protein intake to slower biological aging, but not for everyone https://i.ytimg.com/vi/CPpkKbZebmk/hqdefault.jpg A review of over 350 studies reports that reducing protein intake may slow biological aging and that lower protein intake extended lifespan in flies and rodents; the authors do not recommend that everyone eat less protein. https://www.youtube-nocookie.com/embed/CPpkKbZebmk 161 2026-08-03T05:00:39.000Z 2026-10-22T23:15:48.771Z https://longevityharbor.com/de/watch/CPpkKbZebmk Übersichtsarbeit verbindet geringere Proteinzufuhr mit langsamerem biologischen Altern, aber nicht f https://i.ytimg.com/vi/CPpkKbZebmk/hqdefault.jpg Eine Übersichtsarbeit über mehr als 350 Studien berichtet, dass eine geringere Proteinzufuhr das biologische Altern verlangsamen könnte und dass eine geringere Proteinzufuhr bei Fliegen und Nagetieren die Lebensspanne verlängerte; die Autorinnen und Autoren empfehlen nicht, dass alle weniger Protein essen. https://www.youtube-nocookie.com/embed/CPpkKbZebmk 161 2026-08-03T05:00:39.000Z 2026-10-22T23:15:48.771Z https://longevityharbor.com/en/watch/CQMAVSO2HFo Video description compares three diets for longevity, without results https://i.ytimg.com/vi/CQMAVSO2HFo/hqdefault.jpg The description says the video compares intermittent fasting, the Mediterranean diet and calorie restriction on human lifespan and health span, but it names no study, result or winner. https://www.youtube-nocookie.com/embed/CQMAVSO2HFo 368 2026-07-16T16:23:33.000Z 2026-10-22T23:30:20.517Z https://longevityharbor.com/de/watch/CQMAVSO2HFo Videobeschreibung vergleicht drei Ernährungsformen für Langlebigkeit, ohne Ergebnisse https://i.ytimg.com/vi/CQMAVSO2HFo/hqdefault.jpg Laut Beschreibung vergleicht das Video intermittierendes Fasten, mediterrane Ernährung und Kalorienrestriktion hinsichtlich menschlicher Lebens- und Gesundheitsspanne, nennt aber keine Studie, kein Ergebnis und keinen Sieger. https://www.youtube-nocookie.com/embed/CQMAVSO2HFo 368 2026-07-16T16:23:33.000Z 2026-10-22T23:30:20.517Z https://longevityharbor.com/en/watch/CRT2zuCxFzY Video description: epigenetic clocks and biological age https://i.ytimg.com/vi/CRT2zuCxFzY/hqdefault.jpg The description says epigenetic clocks use DNA methylation and other molecular markers to estimate biological age, going beyond birthday age. No study results are given. https://www.youtube-nocookie.com/embed/CRT2zuCxFzY 99 2026-06-26T18:48:06.000Z 2026-10-22T23:48:05.277Z https://longevityharbor.com/de/watch/CRT2zuCxFzY Videobeschreibung: epigenetische Uhren und biologisches Alter https://i.ytimg.com/vi/CRT2zuCxFzY/hqdefault.jpg Laut Beschreibung schätzen epigenetische Uhren mit DNA-Methylierung und anderen molekularen Markern das biologische Alter, jenseits des Geburtsalters. Studienergebnisse werden nicht genannt. https://www.youtube-nocookie.com/embed/CRT2zuCxFzY 99 2026-06-26T18:48:06.000Z 2026-10-22T23:48:05.277Z https://longevityharbor.com/en/watch/CR_vUfOez8Y Fit im Alter: Gesunde Ernährung für Ältere, Sendung vom 19.08.2024 https://i.ytimg.com/vi/CR_vUfOez8Y/hqdefault.jpg In dieser Sendung gibt euch Nick Bölling Tipps, wie eine gesunde, ausgewogene Ernährung im Alter aussehen soll. https://www.youtube-nocookie.com/embed/CR_vUfOez8Y 1809 2024-08-20T14:17:18.000Z 2026-10-22T18:43:10.907Z https://longevityharbor.com/de/watch/CR_vUfOez8Y Fit im Alter: Gesunde Ernährung für Ältere, Sendung vom 19.08.2024 https://i.ytimg.com/vi/CR_vUfOez8Y/hqdefault.jpg In dieser Sendung gibt euch Nick Bölling Tipps, wie eine gesunde, ausgewogene Ernährung im Alter aussehen soll. https://www.youtube-nocookie.com/embed/CR_vUfOez8Y 1809 2024-08-20T14:17:18.000Z 2026-10-22T18:43:10.907Z https://longevityharbor.com/en/watch/CSIdaEpliAE Video description: rest in old age, muscle loss and circulation https://i.ytimg.com/vi/CSIdaEpliAE/hqdefault.jpg The description says that resting instead of moving can affect muscle mass and strain the cardiovascular system in old age, and it names targeted muscle building and better blood flow as ways to support health. https://www.youtube-nocookie.com/embed/CSIdaEpliAE 702 2026-05-22T13:22:00.000Z 2026-10-23T00:37:22.775Z https://longevityharbor.com/de/watch/CSIdaEpliAE Videobeschreibung: Ruhe im Alter, Muskelabbau und Durchblutung https://i.ytimg.com/vi/CSIdaEpliAE/hqdefault.jpg Die Beschreibung sagt, dass Ausruhen statt Bewegung im Alter die Muskelmasse beeinflussen und das Herz-Kreislauf-System belasten kann; gezielter Muskelaufbau und bessere Durchblutung werden als Wege zu mehr Gesundheit genannt. https://www.youtube-nocookie.com/embed/CSIdaEpliAE 702 2026-05-22T13:22:00.000Z 2026-10-23T00:37:22.775Z https://longevityharbor.com/en/watch/CW04aDMG0Kk Video description: longevity versus frailty and the biology of aging https://i.ytimg.com/vi/CW04aDMG0Kk/hqdefault.jpg The description says the video explains why some people stay vibrant into their 90s while others decline quickly. It lists the Geroscience Hypothesis, hallmarks of aging, lifespan versus healthspan, how frailty is measured, and biological drivers of frailty. Only the description was reviewed. https://www.youtube-nocookie.com/embed/CW04aDMG0Kk 262 2026-10-09T01:00:32.000Z 2026-10-22T20:55:14.118Z https://longevityharbor.com/de/watch/CW04aDMG0Kk Videobeschreibung: Langlebigkeit versus Gebrechlichkeit und die Biologie des Alterns https://i.ytimg.com/vi/CW04aDMG0Kk/hqdefault.jpg Laut Beschreibung erklärt das Video, warum manche Menschen bis in ihre 90er vital bleiben, während andere schnell abbauen. Genannt werden die Geroscience-Hypothese, Hallmarks des Alterns, Lebensspanne versus Gesundheitsspanne, wie Gebrechlichkeit gemessen wird und biologische Treiber der Gebrechlichkeit. Nur die Beschreibung wurde geprüft. https://www.youtube-nocookie.com/embed/CW04aDMG0Kk 262 2026-10-09T01:00:32.000Z 2026-10-22T20:55:14.118Z https://longevityharbor.com/en/watch/CcE7hejk49Q Video description: light, circadian rhythm and recovery after surgery https://i.ytimg.com/vi/CcE7hejk49Q/hqdefault.jpg The description says light is the brain's strongest external circadian cue and that disrupted light-dark rhythms around surgery are linked to poorer sleep and slower recovery; it presents small environmental measures as inexpensive support for orientation. https://www.youtube-nocookie.com/embed/CcE7hejk49Q 178 2026-09-26T22:07:05.000Z 2026-10-22T21:44:14.256Z https://longevityharbor.com/de/watch/CcE7hejk49Q Videobeschreibung: Licht, circadianer Rhythmus und Erholung nach Operation https://i.ytimg.com/vi/CcE7hejk49Q/hqdefault.jpg Die Beschreibung nennt Licht den stärksten äußeren Taktgeber der inneren Uhr und verknüpft gestörte Hell-Dunkel-Rhythmen rund um eine Operation mit schlechterem Schlaf und langsamerer Erholung; kleine Umgebungsmaßnahmen werden als günstige Orientierungshilfe dargestellt. https://www.youtube-nocookie.com/embed/CcE7hejk49Q 178 2026-09-26T22:07:05.000Z 2026-10-22T21:44:14.256Z https://longevityharbor.com/en/watch/CcVp8ltYAFs Video description: late sleep and claimed repair, melatonin and ageing effects https://i.ytimg.com/vi/CcVp8ltYAFs/hqdefault.jpg The description says the video uses medical CGI to explain what happens in the body when people consistently sleep late, naming melatonin, growth hormone, oxidative stress, collagen, circadian rhythm, inflammation and cellular ageing. No results or studies are reported. https://www.youtube-nocookie.com/embed/CcVp8ltYAFs 117 2026-07-11T18:08:35.000Z 2026-10-22T23:35:13.588Z https://longevityharbor.com/de/watch/CcVp8ltYAFs Videobeschreibung: spätes Schlafen und behauptete Effekte auf Reparatur, Melatonin und Altern https://i.ytimg.com/vi/CcVp8ltYAFs/hqdefault.jpg Laut Beschreibung erklärt das Video mit medizinischer CGI, was im Körper passiert, wenn Menschen konsequent spät schlafen, und nennt Melatonin, Wachstumshormon, oxidativen Stress, Kollagen, zirkadianen Rhythmus, Entzündung und zelluläres Altern. Ergebnisse oder Studien werden nicht berichtet. https://www.youtube-nocookie.com/embed/CcVp8ltYAFs 117 2026-07-11T18:08:35.000Z 2026-10-22T23:35:13.588Z https://longevityharbor.com/en/watch/Ce_QnwX6Hgw Caloric Restriction and Longevity: From Calorie- to Time-Restricted Feeding https://i.ytimg.com/vi/Ce_QnwX6Hgw/hqdefault.jpg Eric Ravussin, Ph.D. Boyd Professor Associate Executive Director for Clinical Sciences Douglas L. Gordon Chair in Diabetes and Metabolism Director of the Nutrition Obesity Research Center Pennington Biomedical Research Center Louisiana State University https://www.youtube-nocookie.com/embed/Ce_QnwX6Hgw 3950 2019-02-01T00:13:29.000Z 2026-10-22T17:43:38.428Z https://longevityharbor.com/de/watch/Ce_QnwX6Hgw Caloric Restriction and Longevity: From Calorie- to Time-Restricted Feeding https://i.ytimg.com/vi/Ce_QnwX6Hgw/hqdefault.jpg Eric Ravussin, Ph.D. Boyd Professor Associate Executive Director for Clinical Sciences Douglas L. Gordon Chair in Diabetes and Metabolism Director of the Nutrition Obesity Research Center Pennington Biomedical Research Center Louisiana State University https://www.youtube-nocookie.com/embed/Ce_QnwX6Hgw 3950 2019-02-01T00:13:29.000Z 2026-10-22T17:43:38.428Z https://longevityharbor.com/en/watch/CgQxlY8dBMQ ARDD2025 short talk: proposed nutrients aimed at cellular hallmarks of aging https://i.ytimg.com/vi/CgQxlY8dBMQ/hqdefault.jpg According to the description, Jerome Feige of Nestlé Research and EPFL gave a short talk at the 28th Aging Research and Drug Discovery meeting about novel nutrients targeting cellular hallmarks of aging. The description gives no study design, results or safety data. https://www.youtube-nocookie.com/embed/CgQxlY8dBMQ 1001 2026-02-06T12:51:33.000Z 2026-10-23T02:36:50.783Z https://longevityharbor.com/de/watch/CgQxlY8dBMQ ARDD2025-Kurzvortrag: vorgeschlagene Nährstoffe gegen zelluläre Alternsmerkmale https://i.ytimg.com/vi/CgQxlY8dBMQ/hqdefault.jpg Laut Beschreibung hielt Jerome Feige von Nestlé Research und EPFL beim 28. Aging Research and Drug Discovery Meeting einen Kurzvortrag über neuartige Nährstoffe, die auf zelluläre Alternsmerkmale abzielen. Die Beschreibung nennt weder Studiendesign noch Ergebnisse oder Sicherheitsdaten. https://www.youtube-nocookie.com/embed/CgQxlY8dBMQ 1001 2026-02-06T12:51:33.000Z 2026-10-23T02:36:50.783Z https://longevityharbor.com/en/watch/Cm_L9i0QEsA Podcast: Epigenetic Clocks https://i.ytimg.com/vi/Cm_L9i0QEsA/hqdefault.jpg Do you know your biological age? This episode features audio from: https://nutritionfacts.org/video/epigenetic-clocks-for-testing-your-biological-age/ https://nutritionfacts.org/video/the-role-of-epigenetics-in-the-obesity-epidemic/ https://nutritionfacts.org/video/what-to-eat-to-prevent-telomere-shortening/ Visit the video pages for all sources and doctor's notes related to this podcast. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Books: https://nutritionfacts.org/books • Shop: https://drgreger.org • Facebook: https://www.facebook.com/NutritionFacts.org • Twitter: https://twitter.com/nutrition_facts • Instagram: https://www.instagram.com/nutrition_facts_org https://www.youtube-nocookie.com/embed/Cm_L9i0QEsA 996 2024-12-19T12:59:46.000Z 2026-10-22T18:54:04.247Z https://longevityharbor.com/de/watch/Cm_L9i0QEsA Podcast: Epigenetic Clocks https://i.ytimg.com/vi/Cm_L9i0QEsA/hqdefault.jpg Do you know your biological age? This episode features audio from: https://nutritionfacts.org/video/epigenetic-clocks-for-testing-your-biological-age/ https://nutritionfacts.org/video/the-role-of-epigenetics-in-the-obesity-epidemic/ https://nutritionfacts.org/video/what-to-eat-to-prevent-telomere-shortening/ Visit the video pages for all sources and doctor's notes related to this podcast. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Books: https://nutritionfacts.org/books • Shop: https://drgreger.org • Facebook: https://www.facebook.com/NutritionFacts.org • Twitter: https://twitter.com/nutrition_facts • Instagram: https://www.instagram.com/nutrition_facts_org https://www.youtube-nocookie.com/embed/Cm_L9i0QEsA 996 2024-12-19T12:59:46.000Z 2026-10-22T18:54:04.247Z https://longevityharbor.com/en/watch/CnemxeQ1Fhc Creatine for Healthy Aging: What You Need to Know https://i.ytimg.com/vi/CnemxeQ1Fhc/hqdefault.jpg What actually happens when you take creatine after 50? In this video, we look at what the research says about creatine and healthy aging — including muscle strength, lean mass, brain health, water weight, kidney safety, dosing, and who may benefit the most. We also explain how much creatine to take, whether you need a loading phase, and why consistency may matter more than perfect timing. Creatine is not an anti-aging miracle. But when combined with resistance training, it may be one of the most useful and well-studied supplements for maintaining strength as we get older. In this video: • Why creatine may matter more after 50 • What the evidence says about muscle and strength • Brain and cognition research • How to take creatine • Loading phase vs daily dosing • Water weight and creatinine • Kidney safety • Dehydration and cramps • Who may benefit the most • Final verdict This video is for educational purposes only and is not medical advice. Talk with your healthcare provider before starting a supplement, especially if you have kidney disease or take medications that affect kidney function. Subscribe to AgeCapsule for evidence-based videos on healthy aging, strength, nutrition, sleep, and longevity. Is creatine after 50 safe and effective for maintaining muscle strength? We break down the science of healthy aging. Creatine is often marketed to younger athletes, yet the research suggests it may offer significant support for older adults looking to preserve lean mass. We explore how this supplement interacts with your body as you age, helping you maintain the strength needed for everyday activities and long-term vitality. Our guide covers essential questions including kidney safety, proper dosing, and whether a loading phase is necessary. By combining resistance training with evidence-based supplementation, you can better support your physical health. We also look at the current research regarding brain health and potential cognitive benefits, helping you decide if this addition fits your wellness routine. https://www.youtube-nocookie.com/embed/CnemxeQ1Fhc 734 2026-10-09T04:22:40.000Z 2026-10-22T17:43:36.970Z https://longevityharbor.com/de/watch/CnemxeQ1Fhc Creatine for Healthy Aging: What You Need to Know https://i.ytimg.com/vi/CnemxeQ1Fhc/hqdefault.jpg What actually happens when you take creatine after 50? In this video, we look at what the research says about creatine and healthy aging — including muscle strength, lean mass, brain health, water weight, kidney safety, dosing, and who may benefit the most. We also explain how much creatine to take, whether you need a loading phase, and why consistency may matter more than perfect timing. Creatine is not an anti-aging miracle. But when combined with resistance training, it may be one of the most useful and well-studied supplements for maintaining strength as we get older. In this video: • Why creatine may matter more after 50 • What the evidence says about muscle and strength • Brain and cognition research • How to take creatine • Loading phase vs daily dosing • Water weight and creatinine • Kidney safety • Dehydration and cramps • Who may benefit the most • Final verdict This video is for educational purposes only and is not medical advice. Talk with your healthcare provider before starting a supplement, especially if you have kidney disease or take medications that affect kidney function. Subscribe to AgeCapsule for evidence-based videos on healthy aging, strength, nutrition, sleep, and longevity. Is creatine after 50 safe and effective for maintaining muscle strength? We break down the science of healthy aging. Creatine is often marketed to younger athletes, yet the research suggests it may offer significant support for older adults looking to preserve lean mass. We explore how this supplement interacts with your body as you age, helping you maintain the strength needed for everyday activities and long-term vitality. Our guide covers essential questions including kidney safety, proper dosing, and whether a loading phase is necessary. By combining resistance training with evidence-based supplementation, you can better support your physical health. We also look at the current research regarding brain health and potential cognitive benefits, helping you decide if this addition fits your wellness routine. https://www.youtube-nocookie.com/embed/CnemxeQ1Fhc 734 2026-10-09T04:22:40.000Z 2026-10-22T17:43:36.970Z https://longevityharbor.com/en/watch/CnjiGmvWiIA Doctor's video description: three home exercises for women over 65 https://i.ytimg.com/vi/CnjiGmvWiIA/hqdefault.jpg The description says an orthopedic doctor presents three simple home exercises for women over 65: chair sit-to-stand, standing side leg raise and single-leg stand. It attributes benefits to strength, balance and stability, not proven fall reduction. https://www.youtube-nocookie.com/embed/CnjiGmvWiIA 691 2026-08-13T17:08:34.000Z 2026-10-22T23:02:05.751Z https://longevityharbor.com/de/watch/CnjiGmvWiIA Arzt-Videobeschreibung: drei Übungen zu Hause für Frauen über 65 https://i.ytimg.com/vi/CnjiGmvWiIA/hqdefault.jpg Laut Beschreibung zeigt ein orthopädischer Arzt drei einfache Übungen für zu Hause für Frauen über 65: Aufstehen vom Stuhl, seitliches Beinheben im Stand und Einbeinstand. Er ordnet sie Kraft, Gleichgewicht und Stabilität zu, nicht belegter Sturzreduktion. https://www.youtube-nocookie.com/embed/CnjiGmvWiIA 691 2026-08-13T17:08:34.000Z 2026-10-22T23:02:05.751Z https://longevityharbor.com/en/watch/Cqd7LUarBJg Video description on NMN and NR as NAD⁺ precursors and aging claims https://i.ytimg.com/vi/Cqd7LUarBJg/hqdefault.jpg The description says the video covers what NAD⁺ is, how NMN and NR differ, animal healthspan versus lifespan science, human trial findings, the Sinclair–Brenner debate, and dosing, safety and regulation. It presents no results itself. https://www.youtube-nocookie.com/embed/Cqd7LUarBJg 503 2026-05-07T05:29:09.000Z 2026-10-23T01:07:24.155Z https://longevityharbor.com/de/watch/Cqd7LUarBJg Videobeschreibung zu NMN und NR als NAD⁺-Vorstufen und Alternsaussagen https://i.ytimg.com/vi/Cqd7LUarBJg/hqdefault.jpg Laut Beschreibung behandelt das Video, was NAD⁺ ist, wie sich NMN und NR unterscheiden, Tierforschung zu Gesundheitsspanne versus Lebensspanne, Ergebnisse menschlicher Studien, die Debatte Sinclair–Brenner sowie Dosierung, Sicherheit und Regulierung. Eigene Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/Cqd7LUarBJg 503 2026-05-07T05:29:09.000Z 2026-10-23T01:07:24.155Z https://longevityharbor.com/en/watch/CtK87TPU0BI Die epigenetische Regulierung des Alterns | Naturmedizin | QS24 Gesundheitsfernsehen https://i.ytimg.com/vi/CtK87TPU0BI/hqdefault.jpg Dr. Berit Hippe ist promovierte Ernährungswissenschaftlerin und hat sich mit Ihrem Unternehmen auf personalisierte Ernährung, basierend auf epigenetischen Analysen spezialisiert. In diesem Interview beschreibt sie den Zusammenhang von Lebensstilfaktoren, wie Ernährung, Bewegung und Stressfaktoren auf die epigenetische Regulierung des Alterns. Eine Verkürzung der Telomere, epigenetische Veränderungen an altersrelevanten Genen, vermehrte Entzündungen und die Abnahme der DNA-Stabilität wirken sich negativ auf den Stoffwechsel aus und beschleunigen den Alterungsprozess. Durch langjährige Forschungsarbeiten hat HealthBioCare Marker identifiziert, um komplexe Stoffwechselprozesse einfach zu identifizieren und personalisierte Intervention anzupassen für einen gesunden Alterungsprozess. ▬ Zu Gast ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ Dr. Berit Hippe, Geschäftsführerin von HealthBioCare und Lektorin an der Universität Wien Moderation: Corina Klein Sendungsnummer: NBas_221006_S2_hippe-33 ▬ Kontakt & Links ▬▬▬▬▬▬▬▬▬▬▬▬▬ HealthBioCare GmbH Nußdorfer Straße 67 – 1090 Wien A – Österreich Tel.: +43 677 648 961 33 E-Mail: office@healthbiocare.at Webseite: https://www.healthbiocare.com/ ▬ Abonniere uns ▬▬▬▬▬▬▬▬▬▬▬▬▬▬ Youtube 1: https://www.youtube.com/c/QS24SchweizerPrivatfernsehen?sub_confirmation=1 Youtube 2: https://www.youtube.com/c/QS24TV?sub_confirmation=1 Youtube 3: https://www.youtube.com/channel/UCmwKDjM_TuTWmdQ4ZOg_eXg?sub_confirmation=1 Telegam: https://t.me/QS24_tv Facebook: https://www.facebook.com/qs24official Messenger: https://m.me/qs24official Instagram: https://instagram.com/qs24.tvs ▬ Über QS24 ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ QS24 stellt die erste deutschsprachige Informationsdatenbank dar, die die Naturheilkunde und ganzheitliche Medizin inklusive der Psyche abdeckt. Somit hat man eine weitere Sichtweise in Ergänzung zur herkömmlichen Medizin. Haben Sie nicht genügend Zeit um sich regelmässig die Videos anzuschauen? Dann hören sie unsere Sendungen als Audio Podcast im Auto, im Zug oder wo immer Sie gerade sind unter https://qs24 https://www.youtube-nocookie.com/embed/CtK87TPU0BI 1972 2022-12-31T13:00:10.000Z 2026-10-22T17:11:32.782Z https://longevityharbor.com/de/watch/CtK87TPU0BI Die epigenetische Regulierung des Alterns | Naturmedizin | QS24 Gesundheitsfernsehen https://i.ytimg.com/vi/CtK87TPU0BI/hqdefault.jpg Dr. Berit Hippe ist promovierte Ernährungswissenschaftlerin und hat sich mit Ihrem Unternehmen auf personalisierte Ernährung, basierend auf epigenetischen Analysen spezialisiert. In diesem Interview beschreibt sie den Zusammenhang von Lebensstilfaktoren, wie Ernährung, Bewegung und Stressfaktoren auf die epigenetische Regulierung des Alterns. Eine Verkürzung der Telomere, epigenetische Veränderungen an altersrelevanten Genen, vermehrte Entzündungen und die Abnahme der DNA-Stabilität wirken sich negativ auf den Stoffwechsel aus und beschleunigen den Alterungsprozess. Durch langjährige Forschungsarbeiten hat HealthBioCare Marker identifiziert, um komplexe Stoffwechselprozesse einfach zu identifizieren und personalisierte Intervention anzupassen für einen gesunden Alterungsprozess. ▬ Zu Gast ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ Dr. Berit Hippe, Geschäftsführerin von HealthBioCare und Lektorin an der Universität Wien Moderation: Corina Klein Sendungsnummer: NBas_221006_S2_hippe-33 ▬ Kontakt & Links ▬▬▬▬▬▬▬▬▬▬▬▬▬ HealthBioCare GmbH Nußdorfer Straße 67 – 1090 Wien A – Österreich Tel.: +43 677 648 961 33 E-Mail: office@healthbiocare.at Webseite: https://www.healthbiocare.com/ ▬ Abonniere uns ▬▬▬▬▬▬▬▬▬▬▬▬▬▬ Youtube 1: https://www.youtube.com/c/QS24SchweizerPrivatfernsehen?sub_confirmation=1 Youtube 2: https://www.youtube.com/c/QS24TV?sub_confirmation=1 Youtube 3: https://www.youtube.com/channel/UCmwKDjM_TuTWmdQ4ZOg_eXg?sub_confirmation=1 Telegam: https://t.me/QS24_tv Facebook: https://www.facebook.com/qs24official Messenger: https://m.me/qs24official Instagram: https://instagram.com/qs24.tvs ▬ Über QS24 ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ QS24 stellt die erste deutschsprachige Informationsdatenbank dar, die die Naturheilkunde und ganzheitliche Medizin inklusive der Psyche abdeckt. Somit hat man eine weitere Sichtweise in Ergänzung zur herkömmlichen Medizin. Haben Sie nicht genügend Zeit um sich regelmässig die Videos anzuschauen? Dann hören sie unsere Sendungen als Audio Podcast im Auto, im Zug oder wo immer Sie gerade sind unter https://qs24 https://www.youtube-nocookie.com/embed/CtK87TPU0BI 1972 2022-12-31T13:00:10.000Z 2026-10-22T17:11:32.782Z https://longevityharbor.com/en/watch/CuDm_XmogNQ Wissenschaft beweist: So kannst Du länger leben! https://i.ytimg.com/vi/CuDm_XmogNQ/hqdefault.jpg Wissenschaft beweist: So kannst Du länger leben! Codex Humanus - Das Buch der Menschlichkeit https://www.vitaminum.net/codex-humanus-das-buch-der-menschlichkeit-5-baende-2-bonus-ebooks/sw10124?a_aid=541944beed4d5&a_bid=d9e5ddd5 * Hochwertiges Spermidin https://michael-scherbaum.naturavitalis.de/Spermidin.html * Stellt euch vor, wir könnten das Alter nicht nur aufhalten, sondern sogar umkehren! 🤯 Genau das thematisiert dieses Video, indem es tief in die Wissenschaft des langen Lebens eintaucht und erklärt, wie wir gesund altern können. Wir beleuchten globale Hotspots der Langlebigkeit und entdecken Strategien, um lange leben und ein gesund leben zu führen, damit wir fit im alter bleiben. #antiaging #gesundheit 00:41 Reset für deine Zellen 1:22 Wie soll das Funktionieren? 1:58 Die zerkratzt CD das Alterns 3:12 Kennzeichen des Alterns 4:40 Die "POWER 9" 5:40 Das Handbuch für ein langes Leben 6:13 Die Basis für Langlebigkeit Wissenschaft beweist: So kannst Du länger leben! Die Forschung zur Langlebigkeit (Longevity) hat im frühen 21. Jahrhundert eine Zäsur erfahren und sich von einer rein kurativen hin zu einer proaktiven Präventionsmedizin entwickelt. Das zentrale Ziel ist die Maximierung der Gesundheitsspanne (Healthspan), um diese so weit wie möglich an die maximale Lebensspanne (Lifespan) anzunähern. Aktuell verbringt der Durchschnittsbürger in westlichen Gesellschaften oft die letzten zwei Jahrzehnte seines Lebens in einem Zustand chronischer Krankheit – eine Diskrepanz, die durch gezielte Eingriffe in zelluläre und molekulare Mechanismen minimiert werden soll. Kernpunkte der aktuellen Entwicklung: Paradoxon der Moderne: Menschen leben statistisch länger, aber die Jahre in Krankheit nehmen zu. Longevity-Strategien zielen auf die Qualität dieser Jahre ab. Informationstheorie des Alterns: Altern wird zunehmend als Verlust epigenetischer Information verstanden. Durch partielle zelluläre Reprogrammierung (Einsatz von Yamanaka-Faktoren) konnte in Tierversuchen das biologische Alter bereits umgekehrt werden. Kli https://www.youtube-nocookie.com/embed/CuDm_XmogNQ 538 2026-03-23T13:00:19.000Z 2026-10-22T17:43:39.288Z https://longevityharbor.com/de/watch/CuDm_XmogNQ Wissenschaft beweist: So kannst Du länger leben! https://i.ytimg.com/vi/CuDm_XmogNQ/hqdefault.jpg Wissenschaft beweist: So kannst Du länger leben! Codex Humanus - Das Buch der Menschlichkeit https://www.vitaminum.net/codex-humanus-das-buch-der-menschlichkeit-5-baende-2-bonus-ebooks/sw10124?a_aid=541944beed4d5&a_bid=d9e5ddd5 * Hochwertiges Spermidin https://michael-scherbaum.naturavitalis.de/Spermidin.html * Stellt euch vor, wir könnten das Alter nicht nur aufhalten, sondern sogar umkehren! 🤯 Genau das thematisiert dieses Video, indem es tief in die Wissenschaft des langen Lebens eintaucht und erklärt, wie wir gesund altern können. Wir beleuchten globale Hotspots der Langlebigkeit und entdecken Strategien, um lange leben und ein gesund leben zu führen, damit wir fit im alter bleiben. #antiaging #gesundheit 00:41 Reset für deine Zellen 1:22 Wie soll das Funktionieren? 1:58 Die zerkratzt CD das Alterns 3:12 Kennzeichen des Alterns 4:40 Die "POWER 9" 5:40 Das Handbuch für ein langes Leben 6:13 Die Basis für Langlebigkeit Wissenschaft beweist: So kannst Du länger leben! Die Forschung zur Langlebigkeit (Longevity) hat im frühen 21. Jahrhundert eine Zäsur erfahren und sich von einer rein kurativen hin zu einer proaktiven Präventionsmedizin entwickelt. Das zentrale Ziel ist die Maximierung der Gesundheitsspanne (Healthspan), um diese so weit wie möglich an die maximale Lebensspanne (Lifespan) anzunähern. Aktuell verbringt der Durchschnittsbürger in westlichen Gesellschaften oft die letzten zwei Jahrzehnte seines Lebens in einem Zustand chronischer Krankheit – eine Diskrepanz, die durch gezielte Eingriffe in zelluläre und molekulare Mechanismen minimiert werden soll. Kernpunkte der aktuellen Entwicklung: Paradoxon der Moderne: Menschen leben statistisch länger, aber die Jahre in Krankheit nehmen zu. Longevity-Strategien zielen auf die Qualität dieser Jahre ab. Informationstheorie des Alterns: Altern wird zunehmend als Verlust epigenetischer Information verstanden. Durch partielle zelluläre Reprogrammierung (Einsatz von Yamanaka-Faktoren) konnte in Tierversuchen das biologische Alter bereits umgekehrt werden. Kli https://www.youtube-nocookie.com/embed/CuDm_XmogNQ 538 2026-03-23T13:00:19.000Z 2026-10-22T17:43:39.288Z https://longevityharbor.com/en/watch/CxX9WpQGup4 Cellular Senescence & Aging: Simple Science Explained https://i.ytimg.com/vi/CxX9WpQGup4/hqdefault.jpg Senescence & Aging 👉 Discover how cellular senescence drives the aging process in our bodies. Learn why cells stop dividing, the benefits and drawbacks of this process, and how new research could slow aging and improve health. Unlock the science behind longevity in this easy-to-understand video! 00:00 🔹 What Is Cellular Senescence? 00:29 🔹 Why Do Cells Become Senescent? 01:01 🔹 The Role of Senescent Cells in Aging 01:30 🔹 Benefits and Drawbacks of Cellular Senescence 01:57 🔹 Could Targeting Senescent Cells Slow Aging? 🏷️ cellular senescence, aging process, how aging works, senescent cells, anti-aging science, senolytic therapy, age-related diseases, longevity research, cell biology facts, health and aging 📌 Mind-Blowing Health & Nutrition Facts 🔸 Longevity & Anti-Aging Science 🔸 How Cellular Senescence Impacts Aging: Explained Simply https://www.youtube-nocookie.com/embed/CxX9WpQGup4 146 2025-06-30T23:31:17.000Z 2026-10-22T18:43:13.518Z https://longevityharbor.com/de/watch/CxX9WpQGup4 Cellular Senescence & Aging: Simple Science Explained https://i.ytimg.com/vi/CxX9WpQGup4/hqdefault.jpg Senescence & Aging 👉 Discover how cellular senescence drives the aging process in our bodies. Learn why cells stop dividing, the benefits and drawbacks of this process, and how new research could slow aging and improve health. Unlock the science behind longevity in this easy-to-understand video! 00:00 🔹 What Is Cellular Senescence? 00:29 🔹 Why Do Cells Become Senescent? 01:01 🔹 The Role of Senescent Cells in Aging 01:30 🔹 Benefits and Drawbacks of Cellular Senescence 01:57 🔹 Could Targeting Senescent Cells Slow Aging? 🏷️ cellular senescence, aging process, how aging works, senescent cells, anti-aging science, senolytic therapy, age-related diseases, longevity research, cell biology facts, health and aging 📌 Mind-Blowing Health & Nutrition Facts 🔸 Longevity & Anti-Aging Science 🔸 How Cellular Senescence Impacts Aging: Explained Simply https://www.youtube-nocookie.com/embed/CxX9WpQGup4 146 2025-06-30T23:31:17.000Z 2026-10-22T18:43:13.518Z https://longevityharbor.com/en/watch/D-uGOPvfDeo Peanut Butter and Aging Muscles: What Really Happens Inside Your Body https://i.ytimg.com/vi/D-uGOPvfDeo/hqdefault.jpg What Peanut Butter Really Does to Your Muscles After 60 is a visual science documentary about what happens inside the body after eating peanut butter, and what research actually tells us about aging muscles. As we age, maintaining muscle function becomes increasingly important. But can an ordinary food like peanut butter meaningfully contribute to muscle health? In this episode, we follow peanut butter from digestion to the bloodstream and into the biology of skeletal muscle. We explain dietary protein, amino acids, muscle protein synthesis, muscle power, physical function, and why nutrition cannot be separated from exercise and overall diet quality. We also examine recent research in older adults that specifically studied daily peanut butter consumption and physical function. The findings are more nuanced than the typical “superfood” claims: some measures of physical performance improved, while other measures of muscle strength, muscle mass, gait speed, and body composition did not show significant differences. Most importantly, this video separates what research supports from what is often exaggerated online. You will learn: • How peanut butter is digested and what happens to its nutrients • How dietary protein relates to muscle protein synthesis • Why aging changes the muscle's response to nutrition • What recent peanut butter research in older adults actually found • Why muscle power and muscle mass are not the same thing • Why exercise, overall diet, and individual health still matter • What to consider when choosing peanut butter • Where the evidence is strong, limited, or still developing This video is for educational and informational purposes only. DISCLAIMER: BodyPower3D is not a medical or healthcare provider. The information presented is not medical advice, diagnosis, or treatment. We summarize scientific research and publicly available evidence from reputable sources. Individual health needs and responses may vary. If you have a medical condition, take medication, have a food allergy, or are c https://www.youtube-nocookie.com/embed/D-uGOPvfDeo 988 2026-09-23T14:28:13.000Z 2026-10-22T19:21:29.519Z https://longevityharbor.com/de/watch/D-uGOPvfDeo Peanut Butter and Aging Muscles: What Really Happens Inside Your Body https://i.ytimg.com/vi/D-uGOPvfDeo/hqdefault.jpg What Peanut Butter Really Does to Your Muscles After 60 is a visual science documentary about what happens inside the body after eating peanut butter, and what research actually tells us about aging muscles. As we age, maintaining muscle function becomes increasingly important. But can an ordinary food like peanut butter meaningfully contribute to muscle health? In this episode, we follow peanut butter from digestion to the bloodstream and into the biology of skeletal muscle. We explain dietary protein, amino acids, muscle protein synthesis, muscle power, physical function, and why nutrition cannot be separated from exercise and overall diet quality. We also examine recent research in older adults that specifically studied daily peanut butter consumption and physical function. The findings are more nuanced than the typical “superfood” claims: some measures of physical performance improved, while other measures of muscle strength, muscle mass, gait speed, and body composition did not show significant differences. Most importantly, this video separates what research supports from what is often exaggerated online. You will learn: • How peanut butter is digested and what happens to its nutrients • How dietary protein relates to muscle protein synthesis • Why aging changes the muscle's response to nutrition • What recent peanut butter research in older adults actually found • Why muscle power and muscle mass are not the same thing • Why exercise, overall diet, and individual health still matter • What to consider when choosing peanut butter • Where the evidence is strong, limited, or still developing This video is for educational and informational purposes only. DISCLAIMER: BodyPower3D is not a medical or healthcare provider. The information presented is not medical advice, diagnosis, or treatment. We summarize scientific research and publicly available evidence from reputable sources. Individual health needs and responses may vary. If you have a medical condition, take medication, have a food allergy, or are c https://www.youtube-nocookie.com/embed/D-uGOPvfDeo 988 2026-09-23T14:28:13.000Z 2026-10-22T19:21:29.519Z https://longevityharbor.com/en/watch/D1Na7k5yGQ0 Fasting and autophagy: a video description asking when cellular cleanup begins https://i.ytimg.com/vi/D1Na7k5yGQ0/hqdefault.jpg The description says the video asks when fasting triggers cellular cleanup and whether 12, 16 or 36 hours are needed, and whether the risk outweighs the possible gain. It gives no results, so no answer is established here. https://www.youtube-nocookie.com/embed/D1Na7k5yGQ0 1335 2026-01-29T20:55:06.000Z 2026-10-23T02:45:43.975Z https://longevityharbor.com/de/watch/D1Na7k5yGQ0 Fasten und Autophagie: Eine Videobeschreibung fragt, wann die Zellreinigung beginnt https://i.ytimg.com/vi/D1Na7k5yGQ0/hqdefault.jpg Laut Beschreibung fragt das Video, wann Fasten die Zellreinigung auslöst, ob 12, 16 oder 36 Stunden nötig sind und ob das Risiko den möglichen Gewinn überwiegt. Ergebnisse nennt sie nicht; eine Antwort ist hier nicht belegt. https://www.youtube-nocookie.com/embed/D1Na7k5yGQ0 1335 2026-01-29T20:55:06.000Z 2026-10-23T02:45:43.975Z https://longevityharbor.com/en/watch/D2H3PNo77v8 Podcast: NAD, NMN, NR and Creatine Discussed by Dr. Salzman https://i.ytimg.com/vi/D2H3PNo77v8/hqdefault.jpg In this podcast description, physician-scientist Dr. Andrew Salzman is said to explain NAD's roles in cells, why NAD may decline with age, how CD38 breaks NAD down, how NMN and NR differ, and why creatine may matter for the brain. https://www.youtube-nocookie.com/embed/D2H3PNo77v8 4084 2026-06-25T15:00:06.000Z 2026-10-22T23:48:30.292Z https://longevityharbor.com/de/watch/D2H3PNo77v8 Podcast: Dr. Salzman spricht über NAD, NMN, NR und Kreatin https://i.ytimg.com/vi/D2H3PNo77v8/hqdefault.jpg In dieser Podcast-Beschreibung erklärt der Arzt und Wissenschaftler Dr. Andrew Salzman laut Ankündigung die Aufgaben von NAD in der Zelle, einen möglichen NAD-Rückgang mit dem Alter, den NAD-Abbau durch CD38, Unterschiede zwischen NMN und NR sowie mögliche Bedeutung von Kreatin für das Gehirn. https://www.youtube-nocookie.com/embed/D2H3PNo77v8 4084 2026-06-25T15:00:06.000Z 2026-10-22T23:48:30.292Z https://longevityharbor.com/en/watch/D5sZkXuEAk8 Optimizing Health Through Longevity Science https://i.ytimg.com/vi/D5sZkXuEAk8/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@mkaeberlein What does the science of aging actually tell us—and how much of what we hear in the longevity space is hype? In this keynote lecture from the 2025 Longevity Summit Mauritius, I provide an overview of the biology of aging, the principles of geroscience, and the opportunities and challenges facing the emerging field of Healthspan Medicine. I discuss why biological aging is the single greatest risk factor for most chronic diseases, what we know (and don’t know) about the hallmarks of aging, and why precision and scientific rigor are essential if longevity medicine is going to fulfill its promise. Topics covered include: • What biological aging is—and why it is different from chronological age • The hallmarks of aging and how they are connected through conserved biological pathways • Why targeting aging biology may be more effective than treating individual diseases one at a time • Common misconceptions about aging, longevity, and biological age testing • The current evidence for interventions such as caloric restriction and rapamycin • Lessons from the Dog Aging Project and efforts to extend healthy lifespan in companion animals • Evidence-based approaches to healthspan medicine and proactive healthcare • The limitations of direct-to-consumer biological age tests and microbiome testing • The promise and risks of peptides, supplements, therapeutic plasma exchange, gene therapies, and other emerging interventions • How AI may help scale access to personalized healthspan medicine in the future Throughout the talk, I argue that the longevity field must remain grounded in evidence, transparency, and clinical rigor. While there is tremendous reason for optimism, there is also a need to separate credible science from speculation and marketing if we hope to meaningfully improve health and longevity for people and their companion animals. If you enjoy thoughtful discussions about aging biology, longevity interventions, and the future of healthspan medicine, https://www.youtube-nocookie.com/embed/D5sZkXuEAk8 1933 2026-06-12T16:00:04.000Z 2026-10-22T19:04:37.411Z https://longevityharbor.com/de/watch/D5sZkXuEAk8 Optimizing Health Through Longevity Science https://i.ytimg.com/vi/D5sZkXuEAk8/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@mkaeberlein What does the science of aging actually tell us—and how much of what we hear in the longevity space is hype? In this keynote lecture from the 2025 Longevity Summit Mauritius, I provide an overview of the biology of aging, the principles of geroscience, and the opportunities and challenges facing the emerging field of Healthspan Medicine. I discuss why biological aging is the single greatest risk factor for most chronic diseases, what we know (and don’t know) about the hallmarks of aging, and why precision and scientific rigor are essential if longevity medicine is going to fulfill its promise. Topics covered include: • What biological aging is—and why it is different from chronological age • The hallmarks of aging and how they are connected through conserved biological pathways • Why targeting aging biology may be more effective than treating individual diseases one at a time • Common misconceptions about aging, longevity, and biological age testing • The current evidence for interventions such as caloric restriction and rapamycin • Lessons from the Dog Aging Project and efforts to extend healthy lifespan in companion animals • Evidence-based approaches to healthspan medicine and proactive healthcare • The limitations of direct-to-consumer biological age tests and microbiome testing • The promise and risks of peptides, supplements, therapeutic plasma exchange, gene therapies, and other emerging interventions • How AI may help scale access to personalized healthspan medicine in the future Throughout the talk, I argue that the longevity field must remain grounded in evidence, transparency, and clinical rigor. While there is tremendous reason for optimism, there is also a need to separate credible science from speculation and marketing if we hope to meaningfully improve health and longevity for people and their companion animals. If you enjoy thoughtful discussions about aging biology, longevity interventions, and the future of healthspan medicine, https://www.youtube-nocookie.com/embed/D5sZkXuEAk8 1933 2026-06-12T16:00:04.000Z 2026-10-22T19:04:37.411Z https://longevityharbor.com/en/watch/D61jJJPIQeo Effects of Fasting & Time Restricted Eating on Fat Loss & Health | Huberman Lab Essentials https://i.ytimg.com/vi/D61jJJPIQeo/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this Huberman Lab Essentials episode, I explore intermittent fasting and time-restricted eating, highlighting the positive benefits for weight loss, metabolism, organ health, circadian rhythms and cellular repair. I explain a practical framework for designing a time-restricted eating window that aligns with your lifestyle, exercise schedule and social schedule. I also cover what breaks a fast, how to support fasting with tools like salt intake and post-meal walks, and the use of fasting-related supplements, including berberine and metformin. Episode show notes: https://go.hubermanlab.com/CcvKrMh Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/9tRohh0gErM Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S *Follow Huberman Lab* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Timestamps* 00:00:00 Intermittent Fasting, Time-Restricted Eating (TRE) 00:00:50 Diet, Weight Loss, Calories & Hormones 00:05:52 Body’s Response to Eating vs Fasting, Fasting Duration 00:09:04 Time-Restricted Feeding & Metabolic Benefits, Circadian Gene Rhythm 00:14:32 Optimal Meal Timing, Tool: Extend Sleep-Related Fasts 00:19:42 Eating Window Length, Tools: Adjusting TRE for Building Muscle, Regularity 00:22:34 Accelerate Transition to Fasting, Glucose Clearing, Tool: After-Meal Walk 00:24:16 Metformin, Berberine, Continuous Glucose Monitors; Cell Growth vs Repair, mTOR 00:27:25 Gut Microbiome; Transitioning https://www.youtube-nocookie.com/embed/D61jJJPIQeo 2303 2025-08-28T12:00:22.000Z 2026-10-22T17:43:38.452Z https://longevityharbor.com/de/watch/D61jJJPIQeo Effects of Fasting & Time Restricted Eating on Fat Loss & Health | Huberman Lab Essentials https://i.ytimg.com/vi/D61jJJPIQeo/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this Huberman Lab Essentials episode, I explore intermittent fasting and time-restricted eating, highlighting the positive benefits for weight loss, metabolism, organ health, circadian rhythms and cellular repair. I explain a practical framework for designing a time-restricted eating window that aligns with your lifestyle, exercise schedule and social schedule. I also cover what breaks a fast, how to support fasting with tools like salt intake and post-meal walks, and the use of fasting-related supplements, including berberine and metformin. Episode show notes: https://go.hubermanlab.com/CcvKrMh Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/9tRohh0gErM Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S *Follow Huberman Lab* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Timestamps* 00:00:00 Intermittent Fasting, Time-Restricted Eating (TRE) 00:00:50 Diet, Weight Loss, Calories & Hormones 00:05:52 Body’s Response to Eating vs Fasting, Fasting Duration 00:09:04 Time-Restricted Feeding & Metabolic Benefits, Circadian Gene Rhythm 00:14:32 Optimal Meal Timing, Tool: Extend Sleep-Related Fasts 00:19:42 Eating Window Length, Tools: Adjusting TRE for Building Muscle, Regularity 00:22:34 Accelerate Transition to Fasting, Glucose Clearing, Tool: After-Meal Walk 00:24:16 Metformin, Berberine, Continuous Glucose Monitors; Cell Growth vs Repair, mTOR 00:27:25 Gut Microbiome; Transitioning https://www.youtube-nocookie.com/embed/D61jJJPIQeo 2303 2025-08-28T12:00:22.000Z 2026-10-22T17:43:38.452Z https://longevityharbor.com/en/watch/D9EwDcHvUZs EnsembleAge: Epigenetic Clocks for Aging and Rejuvenation Research https://i.ytimg.com/vi/D9EwDcHvUZs/hqdefault.jpg The link to the original article: https://link.springer.com/article/10.1007/s11357-025-01808-1 Key-words: Epigenetic clocks, Biological age, MethylGauge dataset, EnsembleAge, DNA methylation, Aging biomarkers, Healthspan, Lifespan interventions, Mouse models, Stress response, Rejuvenation, Cross-species analyses, Penalized models, Robustness, Translational research, Human studies, Longevity interventions, Reduced Representation Bisulfite Sequencing (RRBS), Multi-tissue clocks, Caloric restriction, Mammalian Methylation Array, Illumina Infinium platform, CpG sites, Elastic net regression, Ridge regression, Lasso regression, Standardization, Benchmarking datasets, Perturbation experiments, EnsembleAge.Dynamic, EnsembleAge.Static, Genetic disease models, Huntington’s disease, Hutchinson Gilford progeria, Yamanaka factors, Epigenome-wide association studies (EWAS), Chronological age, Mean square error (MSE), Cross-validation, Accuracy, Sensitivity, Specificity, Time to death, Promoter regions, 5’UTRs, CpG islands, Gene set enrichment, Chromatin state, Transcription factors, Precision medicin https://www.youtube-nocookie.com/embed/D9EwDcHvUZs 360 2025-08-13T13:36:28.000Z 2026-10-22T19:21:27.721Z https://longevityharbor.com/de/watch/D9EwDcHvUZs EnsembleAge: Epigenetic Clocks for Aging and Rejuvenation Research https://i.ytimg.com/vi/D9EwDcHvUZs/hqdefault.jpg The link to the original article: https://link.springer.com/article/10.1007/s11357-025-01808-1 Key-words: Epigenetic clocks, Biological age, MethylGauge dataset, EnsembleAge, DNA methylation, Aging biomarkers, Healthspan, Lifespan interventions, Mouse models, Stress response, Rejuvenation, Cross-species analyses, Penalized models, Robustness, Translational research, Human studies, Longevity interventions, Reduced Representation Bisulfite Sequencing (RRBS), Multi-tissue clocks, Caloric restriction, Mammalian Methylation Array, Illumina Infinium platform, CpG sites, Elastic net regression, Ridge regression, Lasso regression, Standardization, Benchmarking datasets, Perturbation experiments, EnsembleAge.Dynamic, EnsembleAge.Static, Genetic disease models, Huntington’s disease, Hutchinson Gilford progeria, Yamanaka factors, Epigenome-wide association studies (EWAS), Chronological age, Mean square error (MSE), Cross-validation, Accuracy, Sensitivity, Specificity, Time to death, Promoter regions, 5’UTRs, CpG islands, Gene set enrichment, Chromatin state, Transcription factors, Precision medicin https://www.youtube-nocookie.com/embed/D9EwDcHvUZs 360 2025-08-13T13:36:28.000Z 2026-10-22T19:21:27.721Z https://longevityharbor.com/en/watch/DCrVHDYrcso Video description: longevity physician urges treating aging and cites $38 trillion delay estimate https://i.ytimg.com/vi/DCrVHDYrcso/hqdefault.jpg According to the description, Dr. David Barzilai told the Timepie Longevity Forum that delaying disease and disability by even one year could yield $38 trillion worldwide, and that targeting the hallmarks of aging is the most powerful path forward. https://www.youtube-nocookie.com/embed/DCrVHDYrcso 1493 2025-12-16T01:00:30.000Z 2026-10-23T03:16:33.542Z https://longevityharbor.com/de/watch/DCrVHDYrcso Videobeschreibung: Longevity-Mediziner fordert Behandlung des Alterns und nennt Schätzung von 38 Bil https://i.ytimg.com/vi/DCrVHDYrcso/hqdefault.jpg Laut Beschreibung sagte Dr. David Barzilai auf dem Timepie Longevity Forum, eine Verzögerung von Krankheit und Behinderung um auch nur ein Jahr könne weltweit 38 Billionen Dollar bringen, und die Hallmarks des Alterns seien der stärkste Weg nach vorn. https://www.youtube-nocookie.com/embed/DCrVHDYrcso 1493 2025-12-16T01:00:30.000Z 2026-10-23T03:16:33.542Z https://longevityharbor.com/en/watch/DEEPayiPDUo James Kirkland at ARDD2023 - Longevity Medicine Day: Aging, Cellular Senescence, and Senolytics... https://i.ytimg.com/vi/DEEPayiPDUo/hqdefault.jpg James Kirkland, MD, PhD, Noaber Foundation Professor of Aging Research Director, Robert and Arlene Kogod Center on Aging presents at the 10th Aging Research and Drug Discovery conference - Longevity Medicine Day: Aging, Cellular Senescence, and Senolytics: The Path to Translation. https://www.youtube-nocookie.com/embed/DEEPayiPDUo 1428 2023-10-26T18:45:01.000Z 2026-10-22T18:43:13.616Z https://longevityharbor.com/de/watch/DEEPayiPDUo James Kirkland at ARDD2023 - Longevity Medicine Day: Aging, Cellular Senescence, and Senolytics... https://i.ytimg.com/vi/DEEPayiPDUo/hqdefault.jpg James Kirkland, MD, PhD, Noaber Foundation Professor of Aging Research Director, Robert and Arlene Kogod Center on Aging presents at the 10th Aging Research and Drug Discovery conference - Longevity Medicine Day: Aging, Cellular Senescence, and Senolytics: The Path to Translation. https://www.youtube-nocookie.com/embed/DEEPayiPDUo 1428 2023-10-26T18:45:01.000Z 2026-10-22T18:43:13.616Z https://longevityharbor.com/en/watch/DElzQqlx41I Video description: NMN as a precursor the body can use to produce NAD⁺ https://i.ytimg.com/vi/DElzQqlx41I/hqdefault.jpg The description says NMN is a naturally occurring molecule and a precursor the body can use to produce NAD⁺, a coenzyme involved in cellular energy metabolism. It calls NMN an interesting area of healthy-aging research. https://www.youtube-nocookie.com/embed/DElzQqlx41I 108 2026-09-25T19:03:04.000Z 2026-10-22T21:48:45.308Z https://longevityharbor.com/de/watch/DElzQqlx41I Videobeschreibung: NMN als Vorstufe, die der Körper zur NAD⁺-Bildung nutzen kann https://i.ytimg.com/vi/DElzQqlx41I/hqdefault.jpg Die Beschreibung nennt NMN ein natürlich vorkommendes Molekül und eine Vorstufe, die der Körper zur Bildung von NAD⁺ nutzen kann, einem Coenzym im zellulären Energiestoffwechsel. NMN wird als interessantes Forschungsfeld zum gesunden Altern bezeichnet. https://www.youtube-nocookie.com/embed/DElzQqlx41I 108 2026-09-25T19:03:04.000Z 2026-10-22T21:48:45.308Z https://longevityharbor.com/en/watch/DK732IuN2xY The Essential Nutrients for Healthy Aging https://i.ytimg.com/vi/DK732IuN2xY/hqdefault.jpg A healthy diet is an important part of healthy aging. Audience members will learn more about how nutrition protects health, prevents disease and promotes an active lifestyle. Dr. Skiba will provide six simple nutrition strategies for healthy aging that audience members can incorporate into their daily lives. https://www.youtube-nocookie.com/embed/DK732IuN2xY 3761 2023-09-21T17:43:17.000Z 2026-10-23T01:53:57.267Z https://longevityharbor.com/de/watch/DK732IuN2xY The Essential Nutrients for Healthy Aging https://i.ytimg.com/vi/DK732IuN2xY/hqdefault.jpg A healthy diet is an important part of healthy aging. Audience members will learn more about how nutrition protects health, prevents disease and promotes an active lifestyle. Dr. Skiba will provide six simple nutrition strategies for healthy aging that audience members can incorporate into their daily lives. https://www.youtube-nocookie.com/embed/DK732IuN2xY 3761 2023-09-21T17:43:17.000Z 2026-10-23T01:53:57.267Z https://longevityharbor.com/en/watch/DMq9_IylgJI Physio’s Secret: 5 Simple Exercises That Help Reverse Aging https://i.ytimg.com/vi/DMq9_IylgJI/hqdefault.jpg Did you know that just 5 simple exercises can help you move and feel 20 years younger? Many people believe weakness and stiffness are part of aging — but research now proves the opposite. You can reverse muscle loss and restore youthful mobility at any age with the right training approach. In this video, you’ll discover: ✅ The top 5 science-backed exercises that rebuild strength and flexibility after 50 ✅ The 2024 study that shows how sarcopenia (age-related muscle loss) can be reversed in weeks ✅ The “Golden Rule of Rehab” — how small, consistent progress can transform your body ✅ Safer, modified versions for every fitness level (including knee, back, or shoulder issues) 💪 These gentle but powerful exercises — Squats, Modified Crunches, Reverse Lunges, Push-Ups, and Glute Bridges — target every major muscle group to help you: Improve balance & posture Boost energy Reduce joint pain Stay independent for years to come Start today, follow along, and see how quickly your body begins to change. 👉 Watch till the end for a simple trick that helps you walk like you’re 20 again! 👍 Like, share, and comment if you’re ready to rebuild your strength naturally. 🔔 Subscribe for more science-based fitness & anti-aging tips for adults over 50. #Over50Fitness #AntiAgingWorkout #ReverseAgingNaturally #LongevityExercises #SeniorHealth #functionalfitness #AntiAgingWorkout #Over50Fitness #ReverseAgingNaturally #SeniorExercise #LongevityTraining #FunctionalFitness #HealthyAging #MobilityExercises #StayYoung #StrongAfter50 https://www.youtube-nocookie.com/embed/DMq9_IylgJI 651 2025-10-13T13:00:20.000Z 2026-10-22T18:32:08.241Z https://longevityharbor.com/de/watch/DMq9_IylgJI Physio’s Secret: 5 Simple Exercises That Help Reverse Aging https://i.ytimg.com/vi/DMq9_IylgJI/hqdefault.jpg Did you know that just 5 simple exercises can help you move and feel 20 years younger? Many people believe weakness and stiffness are part of aging — but research now proves the opposite. You can reverse muscle loss and restore youthful mobility at any age with the right training approach. In this video, you’ll discover: ✅ The top 5 science-backed exercises that rebuild strength and flexibility after 50 ✅ The 2024 study that shows how sarcopenia (age-related muscle loss) can be reversed in weeks ✅ The “Golden Rule of Rehab” — how small, consistent progress can transform your body ✅ Safer, modified versions for every fitness level (including knee, back, or shoulder issues) 💪 These gentle but powerful exercises — Squats, Modified Crunches, Reverse Lunges, Push-Ups, and Glute Bridges — target every major muscle group to help you: Improve balance & posture Boost energy Reduce joint pain Stay independent for years to come Start today, follow along, and see how quickly your body begins to change. 👉 Watch till the end for a simple trick that helps you walk like you’re 20 again! 👍 Like, share, and comment if you’re ready to rebuild your strength naturally. 🔔 Subscribe for more science-based fitness & anti-aging tips for adults over 50. #Over50Fitness #AntiAgingWorkout #ReverseAgingNaturally #LongevityExercises #SeniorHealth #functionalfitness #AntiAgingWorkout #Over50Fitness #ReverseAgingNaturally #SeniorExercise #LongevityTraining #FunctionalFitness #HealthyAging #MobilityExercises #StayYoung #StrongAfter50 https://www.youtube-nocookie.com/embed/DMq9_IylgJI 651 2025-10-13T13:00:20.000Z 2026-10-22T18:32:08.241Z https://longevityharbor.com/en/watch/DTQUAZsNeck Steve Horvath: Our Epigenetic Age Clocks https://i.ytimg.com/vi/DTQUAZsNeck/hqdefault.jpg The inventor looks back on the progress of these clocks over the past decade and where we are headed. Subscribe for more Ground Truths: https://erictopol.substack.com/ https://www.youtube-nocookie.com/embed/DTQUAZsNeck 2485 2024-08-23T15:00:16.000Z 2026-10-22T19:43:51.978Z https://longevityharbor.com/de/watch/DTQUAZsNeck Steve Horvath: Our Epigenetic Age Clocks https://i.ytimg.com/vi/DTQUAZsNeck/hqdefault.jpg The inventor looks back on the progress of these clocks over the past decade and where we are headed. Subscribe for more Ground Truths: https://erictopol.substack.com/ https://www.youtube-nocookie.com/embed/DTQUAZsNeck 2485 2024-08-23T15:00:16.000Z 2026-10-22T19:43:51.978Z https://longevityharbor.com/en/watch/DUnWPfZkk0I 2025 Skincare Trend : The Longevity Code for Youthful, Resilient Skin part 1| INCI with Rinki EP 25 https://i.ytimg.com/vi/DUnWPfZkk0I/hqdefault.jpg EPISODE 25: The Future of Skin Isn’t Serums - It’s Cellular Reprogramming Welcome to Inci with Rinki — the channel where cosmetic science meets storytelling! I’m Rinki, your cosmetic scientist bestie and certified ingredient nerd. In this very special episode, we explore the future of skincare longevity- beyond wrinkles, beyond hydration, and straight into the world of cellular reprogramming. This is Part 1 of my Longevity Series, fresh from my deep dive at In-Cosmetics Amsterdam 2025 — and it's packed with real science, award-winning ingredients, and easy-to-understand analogies. 🧪 WHAT YOU’LL LEARN IN THIS VIDEO: • What is skin longevity and why it’s trending in 2025 • The science behind Clarivine™ - a grape stem cell active that mimics skin fasting • Why PrimalHyal™ UltraReverse is the most advanced hyaluronic acid yet • How both ingredients target hallmarks of aging (epigenetics, telomeres, DNA repair) • Clinical trial data + formulation insights for professionals and enthusiasts alike • Powerful analogies that make complex biochemistry beautifully simple 📍 TIMESTAMPS & KEY MOMENTS 0:00 -Introduction 2:17- The anti-aging myth vs. the longevity mindset 5:43 - Hallmark of aging 6:26 – 1st Longevity Ingredient Launch is Clarivine™ By Vytus Biotech – Plant Fasting Power for Skin Renewal 11:53 – 2nd Longevity Ingredient Launch is PrimalHyal™ UltraReverse by Givaudan Active Beauty - The HA that Talks to DNA 18:00 – Skin Longevity Recap + Why These Actives Matter 💡 WHO IS THIS FOR? If you're a formulator, skincare brand owner, cosmetic chemistry student, or a skin science enthusiast, this episode was made for you. 📣 CALL TO ACTION ✅ Subscribe for more deep dives into active ingredients, formulation trends, and science-based beauty. 💬 COMMENT: What does skin longevity mean to you? 🔗 SHARE this video with a fellow ingredient nerd or skincare creator. 🛎️ Turn on notifications so you don’t miss Part 2: Rebuilding the Skin from Within (coming next week!). 🌿FEATURED INGREDIENTS: • Clarivine™ – https://www.youtube-nocookie.com/embed/DUnWPfZkk0I 1270 2025-05-10T15:33:30.000Z 2026-10-22T19:32:33.542Z https://longevityharbor.com/de/watch/DUnWPfZkk0I 2025 Skincare Trend : The Longevity Code for Youthful, Resilient Skin part 1| INCI with Rinki EP 25 https://i.ytimg.com/vi/DUnWPfZkk0I/hqdefault.jpg EPISODE 25: The Future of Skin Isn’t Serums - It’s Cellular Reprogramming Welcome to Inci with Rinki — the channel where cosmetic science meets storytelling! I’m Rinki, your cosmetic scientist bestie and certified ingredient nerd. In this very special episode, we explore the future of skincare longevity- beyond wrinkles, beyond hydration, and straight into the world of cellular reprogramming. This is Part 1 of my Longevity Series, fresh from my deep dive at In-Cosmetics Amsterdam 2025 — and it's packed with real science, award-winning ingredients, and easy-to-understand analogies. 🧪 WHAT YOU’LL LEARN IN THIS VIDEO: • What is skin longevity and why it’s trending in 2025 • The science behind Clarivine™ - a grape stem cell active that mimics skin fasting • Why PrimalHyal™ UltraReverse is the most advanced hyaluronic acid yet • How both ingredients target hallmarks of aging (epigenetics, telomeres, DNA repair) • Clinical trial data + formulation insights for professionals and enthusiasts alike • Powerful analogies that make complex biochemistry beautifully simple 📍 TIMESTAMPS & KEY MOMENTS 0:00 -Introduction 2:17- The anti-aging myth vs. the longevity mindset 5:43 - Hallmark of aging 6:26 – 1st Longevity Ingredient Launch is Clarivine™ By Vytus Biotech – Plant Fasting Power for Skin Renewal 11:53 – 2nd Longevity Ingredient Launch is PrimalHyal™ UltraReverse by Givaudan Active Beauty - The HA that Talks to DNA 18:00 – Skin Longevity Recap + Why These Actives Matter 💡 WHO IS THIS FOR? If you're a formulator, skincare brand owner, cosmetic chemistry student, or a skin science enthusiast, this episode was made for you. 📣 CALL TO ACTION ✅ Subscribe for more deep dives into active ingredients, formulation trends, and science-based beauty. 💬 COMMENT: What does skin longevity mean to you? 🔗 SHARE this video with a fellow ingredient nerd or skincare creator. 🛎️ Turn on notifications so you don’t miss Part 2: Rebuilding the Skin from Within (coming next week!). 🌿FEATURED INGREDIENTS: • Clarivine™ – https://www.youtube-nocookie.com/embed/DUnWPfZkk0I 1270 2025-05-10T15:33:30.000Z 2026-10-22T19:32:33.542Z https://longevityharbor.com/en/watch/DVNI7b1Pwkw Video description: epigenetic clocks such as PhenoAge and GrimAge https://i.ytimg.com/vi/DVNI7b1Pwkw/hqdefault.jpg The description says epigenetic clocks such as Horvath's and PhenoAge go beyond chronological age and predict mortality risk by analysing biochemical markers and blood cell composition; it also mentions a role in understanding organ dysfunction. https://www.youtube-nocookie.com/embed/DVNI7b1Pwkw 94 2026-06-28T01:30:29.000Z 2026-10-22T23:46:39.693Z https://longevityharbor.com/de/watch/DVNI7b1Pwkw Videobeschreibung: epigenetische Uhren wie PhenoAge und GrimAge https://i.ytimg.com/vi/DVNI7b1Pwkw/hqdefault.jpg Die Beschreibung sagt, epigenetische Uhren wie die von Horvath und PhenoAge gehen über das chronologische Alter hinaus und sagen das Sterberisiko anhand biochemischer Marker und der Blutzusammensetzung voraus; zudem wird eine Rolle beim Verständnis von Organdysfunktion genannt. https://www.youtube-nocookie.com/embed/DVNI7b1Pwkw 94 2026-06-28T01:30:29.000Z 2026-10-22T23:46:39.693Z https://longevityharbor.com/en/watch/DWkdWQFt7jQ Video description on age-related sleep changes and claimed brain mechanisms https://i.ytimg.com/vi/DWkdWQFt7jQ/hqdefault.jpg The description says the video explains why sleep decreases with age, citing a weakening internal clock, a claimed 75% melatonin drop, less deep sleep and a brain waste-clearance system active during sleep. https://www.youtube-nocookie.com/embed/DWkdWQFt7jQ 633 2026-05-26T02:00:37.000Z 2026-10-23T00:25:59.447Z https://longevityharbor.com/de/watch/DWkdWQFt7jQ Videobeschreibung zu altersbezogenen Schlafänderungen und behaupteten Hirnmechanismen https://i.ytimg.com/vi/DWkdWQFt7jQ/hqdefault.jpg Laut Beschreibung erklärt das Video, warum Schlaf mit dem Alter abnimmt, und nennt eine schwächere innere Uhr, einen behaupteten Melatonin-Rückgang um 75 %, weniger Tiefschlaf und ein hirninternes Abfallreinigungssystem, das im Schlaf aktiv ist. https://www.youtube-nocookie.com/embed/DWkdWQFt7jQ 633 2026-05-26T02:00:37.000Z 2026-10-23T00:25:59.447Z https://longevityharbor.com/en/watch/DY2rOHued2A Epigeneticist describes preprint on reducing noise in biological age estimates https://i.ytimg.com/vi/DY2rOHued2A/hqdefault.jpg In the description, epigeneticist Raghav Sehgal discusses a then-preprint study on a new approach to reduce noise and improve the reliability of biological age estimates. The description notes the work was later split: reliability findings are now peer-reviewed in Aging Cell, while the volatility-reduction work is not yet available. https://www.youtube-nocookie.com/embed/DY2rOHued2A 3728 2026-01-21T13:30:22.000Z 2026-10-23T02:48:39.190Z https://longevityharbor.com/de/watch/DY2rOHued2A Epigenetiker beschreibt Preprint zur Verringerung von Rauschen in Schätzungen des biologischen Alter https://i.ytimg.com/vi/DY2rOHued2A/hqdefault.jpg In der Beschreibung erläutert der Epigenetiker Raghav Sehgal eine damals als Preprint vorliegende Studie zu einem neuen Ansatz, um Rauschen zu verringern und die Zuverlässigkeit von Schätzungen des biologischen Alters zu verbessern. Laut Beschreibung wurde die Arbeit später geteilt: Die Reliabilitätsbefunde sind nun in Aging Cell begutachtet, die Arbeit zur Verringerung der Schwankungen ist noch nicht verfügbar. https://www.youtube-nocookie.com/embed/DY2rOHued2A 3728 2026-01-21T13:30:22.000Z 2026-10-23T02:48:39.190Z https://longevityharbor.com/en/watch/DaFYk3lvm7s Muscle function beyond appearance: strength, stability and ageing https://i.ytimg.com/vi/DaFYk3lvm7s/hqdefault.jpg The description says the video explains that muscles do more than make you look strong: they help with safe movement, stabilising the body, balance and everyday tasks, and muscle strength matters increasingly with age for mobility, stability and independence. https://www.youtube-nocookie.com/embed/DaFYk3lvm7s 1390 2026-10-08T10:00:08.000Z 2026-10-22T21:02:47.730Z https://longevityharbor.com/de/watch/DaFYk3lvm7s Muskelfunktion jenseits des Aussehens: Kraft, Stabilität und Altern https://i.ytimg.com/vi/DaFYk3lvm7s/hqdefault.jpg Laut Beschreibung erklärt das Video, dass Muskeln mehr leisten als stark auszusehen: Sie helfen bei sicherer Bewegung, beim Stabilisieren des Körpers, beim Gleichgewicht und bei Alltagsbewegungen; Muskelkraft werde mit zunehmendem Alter wichtiger für Beweglichkeit, Stabilität und Selbstständigkeit. https://www.youtube-nocookie.com/embed/DaFYk3lvm7s 1390 2026-10-08T10:00:08.000Z 2026-10-22T21:02:47.730Z https://longevityharbor.com/en/watch/DbGcs8IHC6c Podcast: Matt Kaeberlein on rapamycin, mTOR and longevity evidence https://i.ytimg.com/vi/DbGcs8IHC6c/hqdefault.jpg In this podcast description, Matt Kaeberlein discusses longevity science, separating exciting laboratory findings on rapamycin and mTOR from open questions about benefits in people. https://www.youtube-nocookie.com/embed/DbGcs8IHC6c 1894 2026-09-29T14:02:02.000Z 2026-10-22T21:38:46.557Z https://longevityharbor.com/de/watch/DbGcs8IHC6c Podcast: Matt Kaeberlein über Rapamycin, mTOR und Langlebigkeits-Belege https://i.ytimg.com/vi/DbGcs8IHC6c/hqdefault.jpg In dieser Podcast-Beschreibung spricht Matt Kaeberlein über Langlebigkeitsforschung und trennt spannende Laborbefunde zu Rapamycin und mTOR von offenen Fragen zum Nutzen beim Menschen. https://www.youtube-nocookie.com/embed/DbGcs8IHC6c 1894 2026-09-29T14:02:02.000Z 2026-10-22T21:38:46.557Z https://longevityharbor.com/en/watch/Df-Bk67IKts Conversations in Oncology: Dr. Levy Interviews Dr. Longo on Fasting and Cancer https://i.ytimg.com/vi/Df-Bk67IKts/hqdefault.jpg In this powerful and wide-ranging interview, world-renowned longevity and fasting expert Dr. Longo shares groundbreaking insights into the use of Fasting Mimicking Diets (FMD) for cancer treatment, longevity, and chronic disease prevention. Dr. Longo explores the intersection of nutritional science, molecular biology, and oncology, challenging traditional views on how we treat illness. While many oncologists focus on adding supplements and nutrients for cancer patients, Dr. Longo takes a radically different approach—using strategic nutrient restriction and fasting cycles to differentiate cancer cells from normal cells, enhance the efficacy of chemotherapy, immunotherapy, and radiotherapy, and improve outcomes with minimal side effects. Dr. Longo discusses the origins of his work at Biosphere 2 with Dr. Roy Walford, where he observed both the promise and limitations of calorie restriction, leading to his development of the FMD: a plant-based, five-day diet designed to mimic the benefits of fasting while preserving gut integrity and patient comfort. He shares compelling preclinical and clinical data showing FMD’s ability to shrink and regenerate organs, activate stem cells, reduce inflammation, and make patients biologically younger. FMD has shown promising results in over 45 clinical trials, including enhanced survival in patients with metastatic triple-negative breast cancer and improvements in conditions like diabetes, prediabetes, obesity, and kidney function. Dr. Longo emphasizes that this isn't about dieting in the traditional sense, but rather using food as medicine—a field he believes could revolutionize healthcare. His nonprofit foundation, Create Cures, based in Los Angeles and Italy, works with thousands of patients through integrated, evidence-based programs that combine FMD with standard cancer therapies, exercise, muscle mass preservation, and mental health support. With independent university-run trials and no personal profit from his books or company, Dr. Longo is on a mission to shift both medica https://www.youtube-nocookie.com/embed/Df-Bk67IKts 2912 2025-05-31T22:28:48.000Z 2026-10-22T18:54:08.202Z https://longevityharbor.com/de/watch/Df-Bk67IKts Conversations in Oncology: Dr. Levy Interviews Dr. Longo on Fasting and Cancer https://i.ytimg.com/vi/Df-Bk67IKts/hqdefault.jpg In this powerful and wide-ranging interview, world-renowned longevity and fasting expert Dr. Longo shares groundbreaking insights into the use of Fasting Mimicking Diets (FMD) for cancer treatment, longevity, and chronic disease prevention. Dr. Longo explores the intersection of nutritional science, molecular biology, and oncology, challenging traditional views on how we treat illness. While many oncologists focus on adding supplements and nutrients for cancer patients, Dr. Longo takes a radically different approach—using strategic nutrient restriction and fasting cycles to differentiate cancer cells from normal cells, enhance the efficacy of chemotherapy, immunotherapy, and radiotherapy, and improve outcomes with minimal side effects. Dr. Longo discusses the origins of his work at Biosphere 2 with Dr. Roy Walford, where he observed both the promise and limitations of calorie restriction, leading to his development of the FMD: a plant-based, five-day diet designed to mimic the benefits of fasting while preserving gut integrity and patient comfort. He shares compelling preclinical and clinical data showing FMD’s ability to shrink and regenerate organs, activate stem cells, reduce inflammation, and make patients biologically younger. FMD has shown promising results in over 45 clinical trials, including enhanced survival in patients with metastatic triple-negative breast cancer and improvements in conditions like diabetes, prediabetes, obesity, and kidney function. Dr. Longo emphasizes that this isn't about dieting in the traditional sense, but rather using food as medicine—a field he believes could revolutionize healthcare. His nonprofit foundation, Create Cures, based in Los Angeles and Italy, works with thousands of patients through integrated, evidence-based programs that combine FMD with standard cancer therapies, exercise, muscle mass preservation, and mental health support. With independent university-run trials and no personal profit from his books or company, Dr. Longo is on a mission to shift both medica https://www.youtube-nocookie.com/embed/Df-Bk67IKts 2912 2025-05-31T22:28:48.000Z 2026-10-22T18:54:08.202Z https://longevityharbor.com/en/watch/DfiObG6D_NM Measuring biological age with epigenetic aging clocks | Dr. Morgan Levine https://i.ytimg.com/vi/DfiObG6D_NM/hqdefault.jpg In this clip, Drs. Levine and Patrick discuss the advantage of using epigenetic clocks in aging research to measure biological age. Dr. Levine then explains the difference between first and second-generation epigenetic aging clocks. Interview published on April 12, 2022 Watch the full episode: https://youtu.be/_dOofH4PC9w #aging #epigenetics #agingclock https://www.youtube-nocookie.com/embed/DfiObG6D_NM 487 2022-05-20T17:00:07.000Z 2026-10-22T17:43:35.250Z https://longevityharbor.com/de/watch/DfiObG6D_NM Measuring biological age with epigenetic aging clocks | Dr. Morgan Levine https://i.ytimg.com/vi/DfiObG6D_NM/hqdefault.jpg In this clip, Drs. Levine and Patrick discuss the advantage of using epigenetic clocks in aging research to measure biological age. Dr. Levine then explains the difference between first and second-generation epigenetic aging clocks. Interview published on April 12, 2022 Watch the full episode: https://youtu.be/_dOofH4PC9w #aging #epigenetics #agingclock https://www.youtube-nocookie.com/embed/DfiObG6D_NM 487 2022-05-20T17:00:07.000Z 2026-10-22T17:43:35.250Z https://longevityharbor.com/en/watch/DjTtyfokTX0 What FASTING Does to Your Cells That Exercise Can’t https://i.ytimg.com/vi/DjTtyfokTX0/hqdefault.jpg #autophagy #fastingscience #cellularhealth What FASTING Does to Your Cells That Exercise Can’t What if fasting was never really about weight loss? What if the real story was happening deep inside your cells — at a molecular level so extraordinary that one scientist won the Nobel Prize just for discovering it? In this video, we break down the science of autophagy — your body's built-in cellular cleanup system that only fully activates when you stop eating. And the results will completely change how you think about food, timing, and aging. Here's what we cover: ✅ What autophagy really is — and why exercise alone can't trigger it ✅ The Nobel Prize-winning discovery by Yoshinori Ohsumi in 2016 ✅ What happens inside your cells at 16, 24, 48, and 72 hours of fasting ✅ The FOXO3 longevity gene found in people who live past 100 ✅ How NAD+ and sirtuins control aging — and how fasting boosts both ✅ The MIT 2019 stem cell study that shocked the scientific community ✅ Dr. Valter Longo's research on fasting and immune system regeneration ✅ How ketones fuel your brain better than glucose — and protect neurons ✅ The mTOR pathway, mitophagy, and why your cell can't build and clean at the same time ✅ Practical time-restricted eating tips — no extreme 72-hour fasts required This isn't a diet video. This is the biology your body has been running since before civilization — and why the modern eating schedule keeps hitting the pause button on your most powerful internal system. 🔔 SUBSCRIBE — We drop science that actually changes how you see the world. Hit the bell so you never miss a video. 👍 LIKE this video if it made you rethink something — it genuinely helps more people find this research. 💬 COMMENT below — Have you ever tried fasting? Did you feel that mental clarity at hour 14-16? Let's talk. 🔑 KEYWORDS: autophagy explained, what fasting does to your body, intermittent fasting science, fasting vs exercise, cellular autophagy, mitophagy explained, mTOR pathway fasting, FOXO3 longevity gene, NAD+ aging research, sirt https://www.youtube-nocookie.com/embed/DjTtyfokTX0 1226 2026-10-08T12:00:06.000Z 2026-10-22T19:32:31.832Z https://longevityharbor.com/de/watch/DjTtyfokTX0 What FASTING Does to Your Cells That Exercise Can’t https://i.ytimg.com/vi/DjTtyfokTX0/hqdefault.jpg #autophagy #fastingscience #cellularhealth What FASTING Does to Your Cells That Exercise Can’t What if fasting was never really about weight loss? What if the real story was happening deep inside your cells — at a molecular level so extraordinary that one scientist won the Nobel Prize just for discovering it? In this video, we break down the science of autophagy — your body's built-in cellular cleanup system that only fully activates when you stop eating. And the results will completely change how you think about food, timing, and aging. Here's what we cover: ✅ What autophagy really is — and why exercise alone can't trigger it ✅ The Nobel Prize-winning discovery by Yoshinori Ohsumi in 2016 ✅ What happens inside your cells at 16, 24, 48, and 72 hours of fasting ✅ The FOXO3 longevity gene found in people who live past 100 ✅ How NAD+ and sirtuins control aging — and how fasting boosts both ✅ The MIT 2019 stem cell study that shocked the scientific community ✅ Dr. Valter Longo's research on fasting and immune system regeneration ✅ How ketones fuel your brain better than glucose — and protect neurons ✅ The mTOR pathway, mitophagy, and why your cell can't build and clean at the same time ✅ Practical time-restricted eating tips — no extreme 72-hour fasts required This isn't a diet video. This is the biology your body has been running since before civilization — and why the modern eating schedule keeps hitting the pause button on your most powerful internal system. 🔔 SUBSCRIBE — We drop science that actually changes how you see the world. Hit the bell so you never miss a video. 👍 LIKE this video if it made you rethink something — it genuinely helps more people find this research. 💬 COMMENT below — Have you ever tried fasting? Did you feel that mental clarity at hour 14-16? Let's talk. 🔑 KEYWORDS: autophagy explained, what fasting does to your body, intermittent fasting science, fasting vs exercise, cellular autophagy, mitophagy explained, mTOR pathway fasting, FOXO3 longevity gene, NAD+ aging research, sirt https://www.youtube-nocookie.com/embed/DjTtyfokTX0 1226 2026-10-08T12:00:06.000Z 2026-10-22T19:32:31.832Z https://longevityharbor.com/en/watch/DkSuMIp5uMc Video description claims five exercises reverse muscle aging https://i.ytimg.com/vi/DkSuMIp5uMc/hqdefault.jpg The description presents progressive strength training and five movements (squat, modified crunch, reverse lunge, modified push-up, glute bridge) as a way to counter age-related muscle loss, with a suggested progression from 2 sets of 10 and about 20% more volume weekly. These are creator claims in the description only. https://www.youtube-nocookie.com/embed/DkSuMIp5uMc 834 2026-03-05T11:19:40.000Z 2026-10-23T02:12:52.789Z https://longevityharbor.com/de/watch/DkSuMIp5uMc Videobeschreibung behauptet, fünf Übungen kehren Muskelalterung um https://i.ytimg.com/vi/DkSuMIp5uMc/hqdefault.jpg Die Beschreibung stellt progressives Krafttraining und fünf Bewegungen (Kniebeuge, modifizierter Crunch, Ausfallschritt rückwärts, modifizierter Liegestütz, Glute Bridge) als Mittel gegen altersbezogenen Muskelverlust dar, mit einem Vorschlag von 2 Sätzen à 10 und etwa 20 % mehr Volumen pro Woche. Das sind Aussagen des Erstellers nur aus der Beschreibung. https://www.youtube-nocookie.com/embed/DkSuMIp5uMc 834 2026-03-05T11:19:40.000Z 2026-10-23T02:12:52.789Z https://longevityharbor.com/en/watch/DpFzni7jS3I Assessing the Utility of Epigenetic Clocks for Health Prediction in South Korean https://i.ytimg.com/vi/DpFzni7jS3I/hqdefault.jpg The development and recent increase in the application of epigenetic clocks in healthcare research has primarily been focused among European, African, or Hispanic individuals. The use of epigenetic clocks is limited among the east Asian population despite having notable differences in epigenetic clocks among various ethnic groups. If the biological age is higher than chronological age, it is called Epigenetic Age Acceleration (EAA). It is typically derived by regressing the epigenetic age of clocks on chronological age, assessing whether individuals are aging faster or slower than their chronological age. EAA indicates higher risk of chronic diseases, mortality, and adverse health outcomes and thereby indicates faster aging. Read more (https://www.celltalk.org/ananya-khan-presentation https://www.omicsfi.org/biovanguardfellows/ananya-khan) #EpigeneticClocks #SouthKorea #Aging #EpigeneticAgeAcceleration #AdverseHealthoutcomes #HealthcareResearch #ChronologicalAge #ChronicDiseases #Mortality #HealthyLifestyle #Lifesciences #HealthJournals #JournalClub #Longevity #Bioscience #DNA #YouTube #HealthyLife #CellTalk For more interesting videos --------------------------------------------- Subscribe to CellTalk: https://www.youtube.com/@celltalk8633 You may also like to watch: Making Beneficial Use of Wearable Device Data in Patient Care Connect with us on social: --------------------------------------------- LinkedIn: https://www.linkedin.com/company/celltalk/ Facebook: https://www.facebook.com/CellTalkOrg Visit CellTalk: https://www.celltalk.org/ https://www.youtube-nocookie.com/embed/DpFzni7jS3I 998 2025-02-07T07:29:53.000Z 2026-10-22T18:54:04.102Z https://longevityharbor.com/de/watch/DpFzni7jS3I Assessing the Utility of Epigenetic Clocks for Health Prediction in South Korean https://i.ytimg.com/vi/DpFzni7jS3I/hqdefault.jpg The development and recent increase in the application of epigenetic clocks in healthcare research has primarily been focused among European, African, or Hispanic individuals. The use of epigenetic clocks is limited among the east Asian population despite having notable differences in epigenetic clocks among various ethnic groups. If the biological age is higher than chronological age, it is called Epigenetic Age Acceleration (EAA). It is typically derived by regressing the epigenetic age of clocks on chronological age, assessing whether individuals are aging faster or slower than their chronological age. EAA indicates higher risk of chronic diseases, mortality, and adverse health outcomes and thereby indicates faster aging. Read more (https://www.celltalk.org/ananya-khan-presentation https://www.omicsfi.org/biovanguardfellows/ananya-khan) #EpigeneticClocks #SouthKorea #Aging #EpigeneticAgeAcceleration #AdverseHealthoutcomes #HealthcareResearch #ChronologicalAge #ChronicDiseases #Mortality #HealthyLifestyle #Lifesciences #HealthJournals #JournalClub #Longevity #Bioscience #DNA #YouTube #HealthyLife #CellTalk For more interesting videos --------------------------------------------- Subscribe to CellTalk: https://www.youtube.com/@celltalk8633 You may also like to watch: Making Beneficial Use of Wearable Device Data in Patient Care Connect with us on social: --------------------------------------------- LinkedIn: https://www.linkedin.com/company/celltalk/ Facebook: https://www.facebook.com/CellTalkOrg Visit CellTalk: https://www.celltalk.org/ https://www.youtube-nocookie.com/embed/DpFzni7jS3I 998 2025-02-07T07:29:53.000Z 2026-10-22T18:54:04.102Z https://longevityharbor.com/en/watch/DrBa1e5Uu2Y Metformin, rapamycin and geroscience drugs: eye outcomes in a video description https://i.ytimg.com/vi/DrBa1e5Uu2Y/hqdefault.jpg The description says observational studies link metformin to lower rates of age-related macular degeneration and glaucoma, but a 16-year follow-up found no difference in AMD rates, and glaucoma results were mixed. https://www.youtube-nocookie.com/embed/DrBa1e5Uu2Y 1300 2026-02-07T11:00:45.000Z 2026-10-23T02:36:42.048Z https://longevityharbor.com/de/watch/DrBa1e5Uu2Y Metformin, Rapamycin und Gerowissenschafts-Medikamente: Augenfolgen in einer Videobeschreibung https://i.ytimg.com/vi/DrBa1e5Uu2Y/hqdefault.jpg Die Beschreibung berichtet, Beobachtungsstudien verbinden Metformin mit niedrigeren Raten altersbezogener Makuladegeneration und Glaukoms, doch eine 16-Jahres-Nachbeobachtung fand keinen Unterschied bei AMD-Raten, und die Glaukom-Ergebnisse waren gemischt. https://www.youtube-nocookie.com/embed/DrBa1e5Uu2Y 1300 2026-02-07T11:00:45.000Z 2026-10-23T02:36:42.048Z https://longevityharbor.com/en/watch/Dtshb3n4Y6U The Hallmarks of Aging: Cellular senescence | LifeXtenShow https://i.ytimg.com/vi/Dtshb3n4Y6U/hqdefault.jpg Believe it or not, there probably are zombie cells in your body right now, and they’re helping to stage one of the scariest molecular biology horror movies: aging. Thanks to Kali Carrigan for writing the script! Liked the show? Let us know on Twitter at https://twitter.com/lifespanio or our Discord server at https://discord.gg/HwTX7gR Facebook: https://www.facebook.com/lifespanio/ LinkedIn: https://www.linkedin.com/company/lifespanio Instagram: https://www.instagram.com/lifespan.io Website: https://www.leafscience.org/ Stock contents: Shutterstock, Videoblocks Music: Intro jingle courtesy of Kevin MacLeod - Incompetech.com Crumbling rocks sound effect: Opsaaaaa (freesound.org) -------------------------- Sources: López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. Cell, 153(6), 1194-1217. Baar, M. P., Brandt, R. M., Putavet, D. A., Klein, J. D., Derks, K. W., Bourgeois, B. R., ... & van der Pluijm, I. (2017). Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging. Cell, 169(1), 132-147. Hernandez-Segura, A., Nehme, J., & Demaria, M. (2018). Hallmarks of Cellular Senescence. Trends in Cell Biology, 28(6), 436–453. doi:10.1016/j.tcb.2018.02.001 Collado, M., Blasco, M. A., & Serrano, M. (2007). Cellular senescence in cancer and aging. Cell, 130(2), 223-233. Campisi, J. (2001). Cellular senescence as a tumor-suppressor mechanism. Trends in cell biology, 11(11), S27-S31. Demaria, M., Ohtani, N., Youssef, S. A., Rodier, F., Toussaint, W., Mitchell, J. R., ... & Hoeijmakers, J. H. (2014). An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA. Developmental cell, 31(6), 722-733. Hickson, L. J., Prata, L. G. L., Bobart, S. A., Evans, T. K., Giorgadze, N., Hashmi, S. K., ... & Kellogg, T. A. (2019). Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease. EBioMedicin https://www.youtube-nocookie.com/embed/Dtshb3n4Y6U 643 2020-05-21T14:59:21.000Z 2026-10-22T17:43:40.088Z https://longevityharbor.com/de/watch/Dtshb3n4Y6U The Hallmarks of Aging: Cellular senescence | LifeXtenShow https://i.ytimg.com/vi/Dtshb3n4Y6U/hqdefault.jpg Believe it or not, there probably are zombie cells in your body right now, and they’re helping to stage one of the scariest molecular biology horror movies: aging. Thanks to Kali Carrigan for writing the script! Liked the show? Let us know on Twitter at https://twitter.com/lifespanio or our Discord server at https://discord.gg/HwTX7gR Facebook: https://www.facebook.com/lifespanio/ LinkedIn: https://www.linkedin.com/company/lifespanio Instagram: https://www.instagram.com/lifespan.io Website: https://www.leafscience.org/ Stock contents: Shutterstock, Videoblocks Music: Intro jingle courtesy of Kevin MacLeod - Incompetech.com Crumbling rocks sound effect: Opsaaaaa (freesound.org) -------------------------- Sources: López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. Cell, 153(6), 1194-1217. Baar, M. P., Brandt, R. M., Putavet, D. A., Klein, J. D., Derks, K. W., Bourgeois, B. R., ... & van der Pluijm, I. (2017). Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging. Cell, 169(1), 132-147. Hernandez-Segura, A., Nehme, J., & Demaria, M. (2018). Hallmarks of Cellular Senescence. Trends in Cell Biology, 28(6), 436–453. doi:10.1016/j.tcb.2018.02.001 Collado, M., Blasco, M. A., & Serrano, M. (2007). Cellular senescence in cancer and aging. Cell, 130(2), 223-233. Campisi, J. (2001). Cellular senescence as a tumor-suppressor mechanism. Trends in cell biology, 11(11), S27-S31. Demaria, M., Ohtani, N., Youssef, S. A., Rodier, F., Toussaint, W., Mitchell, J. R., ... & Hoeijmakers, J. H. (2014). An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA. Developmental cell, 31(6), 722-733. Hickson, L. J., Prata, L. G. L., Bobart, S. A., Evans, T. K., Giorgadze, N., Hashmi, S. K., ... & Kellogg, T. A. (2019). Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease. EBioMedicin https://www.youtube-nocookie.com/embed/Dtshb3n4Y6U 643 2020-05-21T14:59:21.000Z 2026-10-22T17:43:40.088Z https://longevityharbor.com/en/watch/Due7gt5OrDU Video description: five aging hallmarks said to respond to diet and lifestyle https://i.ytimg.com/vi/Due7gt5OrDU/hqdefault.jpg The description names five of up to 14 interconnected aging mechanisms as most directly responsive to diet and lifestyle, and says these non-drug interventions act on metabolic signaling to restore cellular balance and slow biological decline. https://www.youtube-nocookie.com/embed/Due7gt5OrDU 487 2026-09-12T12:00:20.000Z 2026-10-22T22:17:00.865Z https://longevityharbor.com/de/watch/Due7gt5OrDU Videobeschreibung: fünf Alternsmerkmale, die laut Beschreibung auf Ernährung und Lebensstil reagiere https://i.ytimg.com/vi/Due7gt5OrDU/hqdefault.jpg Die Beschreibung nennt fünf von bis zu 14 miteinander verbundenen Alternsmechanismen als am direktesten auf Ernährung und Lebensstil reagierend und sagt, diese nicht-medikamentösen Maßnahmen wirkten auf metabolische Signalwege, um die zelluläre Balance wiederherzustellen und den biologischen Abbau zu verlangsamen. https://www.youtube-nocookie.com/embed/Due7gt5OrDU 487 2026-09-12T12:00:20.000Z 2026-10-22T22:17:00.865Z https://longevityharbor.com/en/watch/E6cj67KvoyI Protein needs across life stages and animal longevity findings https://i.ytimg.com/vi/E6cj67KvoyI/hqdefault.jpg The description says protein needs shift with age and that animal study results on lower protein and longer lifespan do not map neatly onto human biology. https://www.youtube-nocookie.com/embed/E6cj67KvoyI 795 2026-09-09T15:00:00.000Z 2026-10-22T22:23:35.837Z https://longevityharbor.com/de/watch/E6cj67KvoyI Proteinbedarf im Lebensverlauf und Langlebigkeitsbefunde aus Tierstudien https://i.ytimg.com/vi/E6cj67KvoyI/hqdefault.jpg Laut Beschreibung verändert sich der Proteinbedarf mit dem Alter, und Ergebnisse aus Tierstudien zu weniger Protein und längerem Leben lassen sich nicht einfach auf die menschliche Biologie übertragen. https://www.youtube-nocookie.com/embed/E6cj67KvoyI 795 2026-09-09T15:00:00.000Z 2026-10-22T22:23:35.837Z https://longevityharbor.com/en/watch/E7WXzxSt4VY Peptides, Cancer, and the Truth About Longevity Medicine | Dr. Alex https://i.ytimg.com/vi/E7WXzxSt4VY/hqdefault.jpg subscribe to Truth Hurts Show for unfiltered discussions, honest takes, and conversations most people avoid: https://www.youtube.com/@TruthHurtsShow?sub_confirmation=1 Podcast: https://podcasts.apple.com/us/podcast/truth-hurts-show/id1653918528 Explore the power of peptides for longevity and learn how they can help slow down the aging process. Peptides like BPC 157, GHK, and thymus-derived peptides are well-researched and offer potential benefits in rejuvenation and health optimization. Discover how these compounds can target hallmarks of aging, including telomere attrition and mitochondrial dysfunction, and support a healthier, longer life. In addition to peptides, understand the role of lifestyle interventions, such as optimizing sleep, nutrition, and exercise, in promoting longevity. Learn why personalized approaches are crucial in longevity science and how factors like inflammation, immune health, and emotional well-being impact aging. Start your journey to a healthier, longer life today by integrating these insights into your wellness routine. Follow US! YouTube: @TruthHurtsShow Brian's Links Instagram: https://www.instagram.com/briangoldphd TikTok: https://www.tiktok.com/@briangoldphd Makan's Links Instagram: https://www.instagram.com/makan_mostafavi TikTok: https://www.tiktok.com/@makanmostafavi Dr. Alex Links https://infinityepigenetics.com/ Timestamps 0:00 Peptides for regeneration and cancer risk 2:06 Latest interventions for longevity 5:10 Sleep, stress, and their epigenetic impact 8:19 Dr. Alex’s path from psychiatry to biotech 12:08 The most advanced anti-aging protocols today 15:01 Longevity on a budget, where to start 17:03 Why cold plunges and keto may be dangerous 21:22 Foods that fuel (or fight) inflammation 29:10 Hallmarks of aging and how to target them 36:06 How to test early for cancer and hidden disease 39:00 The immune system’s role in longevity 43:14 Final advice and where to find Dr. Alex #PeptidesForHealth, #LongevityTips, #SlowAging, #RegenerativeHealth, #HealthyAgin https://www.youtube-nocookie.com/embed/E7WXzxSt4VY 2651 2025-12-16T20:03:15.000Z 2026-10-22T17:43:39.345Z https://longevityharbor.com/de/watch/E7WXzxSt4VY Peptides, Cancer, and the Truth About Longevity Medicine | Dr. Alex https://i.ytimg.com/vi/E7WXzxSt4VY/hqdefault.jpg subscribe to Truth Hurts Show for unfiltered discussions, honest takes, and conversations most people avoid: https://www.youtube.com/@TruthHurtsShow?sub_confirmation=1 Podcast: https://podcasts.apple.com/us/podcast/truth-hurts-show/id1653918528 Explore the power of peptides for longevity and learn how they can help slow down the aging process. Peptides like BPC 157, GHK, and thymus-derived peptides are well-researched and offer potential benefits in rejuvenation and health optimization. Discover how these compounds can target hallmarks of aging, including telomere attrition and mitochondrial dysfunction, and support a healthier, longer life. In addition to peptides, understand the role of lifestyle interventions, such as optimizing sleep, nutrition, and exercise, in promoting longevity. Learn why personalized approaches are crucial in longevity science and how factors like inflammation, immune health, and emotional well-being impact aging. Start your journey to a healthier, longer life today by integrating these insights into your wellness routine. Follow US! YouTube: @TruthHurtsShow Brian's Links Instagram: https://www.instagram.com/briangoldphd TikTok: https://www.tiktok.com/@briangoldphd Makan's Links Instagram: https://www.instagram.com/makan_mostafavi TikTok: https://www.tiktok.com/@makanmostafavi Dr. Alex Links https://infinityepigenetics.com/ Timestamps 0:00 Peptides for regeneration and cancer risk 2:06 Latest interventions for longevity 5:10 Sleep, stress, and their epigenetic impact 8:19 Dr. Alex’s path from psychiatry to biotech 12:08 The most advanced anti-aging protocols today 15:01 Longevity on a budget, where to start 17:03 Why cold plunges and keto may be dangerous 21:22 Foods that fuel (or fight) inflammation 29:10 Hallmarks of aging and how to target them 36:06 How to test early for cancer and hidden disease 39:00 The immune system’s role in longevity 43:14 Final advice and where to find Dr. Alex #PeptidesForHealth, #LongevityTips, #SlowAging, #RegenerativeHealth, #HealthyAgin https://www.youtube-nocookie.com/embed/E7WXzxSt4VY 2651 2025-12-16T20:03:15.000Z 2026-10-22T17:43:39.345Z https://longevityharbor.com/en/watch/EA-lCcBKtrg "Try It For 1 Week" - Most Effective Way To REVERSE AGING IN DAYS! https://i.ytimg.com/vi/EA-lCcBKtrg/hqdefault.jpg Repair Your Cells in 30 Days 👉 https://doctorbecker.netlify.app 😴 Exhausted by 2PM? Brain fog? Weight won't budge? ⬇️ 2.6M+ viewed this protocol — now it's yours: 🔬 https://doctorbecker.netlify.app 30 days. 7 foods. No pills. No gym. Backed by 28 studies. ⚠️ MEDICAL EDUCATION DISCLAIMER This video provides educational information about the hallmarks of aging and evidence-based dietary interventions. All recommendations are based on peer-reviewed research and 15+ years of clinical experience, but should not replace personalized medical advice. Always consult your healthcare provider before making changes to your health regimen, especially if you have existing conditions or take medications. Individual results may vary. This content is intended for adults 50+ interested in evidence-based health information. 93% of adults over 50 show accelerated biological aging in at least one organ system. But the 12 hallmarks driving that acceleration are not mysterious and they are not irreversible. In this video, Dr. Becker breaks down the peer-reviewed science showing how specific foods and a simple fasting window can target multiple aging mechanisms simultaneously — mitophagy, autophagy, NRF2 activation, and nitric oxide production — using nothing more than what you can find at any grocery store. 🔴 Key Topics Covered: - The 12 Hallmarks of Aging (Cell 2023 update) and how they cascade - Mitophagy activation through urolithin A from pomegranate and berries - How a 12-hour overnight fast enhances autophagy (first human trial) - Sulforaphane from broccoli sprouts activating 200+ protective genes via NRF2 - Nitric oxide production from spinach and your tongue microbiome - EGCG from green tea and the hormesis mechanism - Beans, legumes, and the Blue Zones gut microbiome connection - A complete 7-day starting protocol with specific doses and preparation methods What if the most powerful anti-aging intervention isn't an expensive supplement or experimental therapy — but what you put on your plate and when you stop eatin https://www.youtube-nocookie.com/embed/EA-lCcBKtrg 1396 2026-04-07T21:00:00.000Z 2026-10-22T19:54:19.249Z https://longevityharbor.com/de/watch/EA-lCcBKtrg "Try It For 1 Week" - Most Effective Way To REVERSE AGING IN DAYS! https://i.ytimg.com/vi/EA-lCcBKtrg/hqdefault.jpg Repair Your Cells in 30 Days 👉 https://doctorbecker.netlify.app 😴 Exhausted by 2PM? Brain fog? Weight won't budge? ⬇️ 2.6M+ viewed this protocol — now it's yours: 🔬 https://doctorbecker.netlify.app 30 days. 7 foods. No pills. No gym. Backed by 28 studies. ⚠️ MEDICAL EDUCATION DISCLAIMER This video provides educational information about the hallmarks of aging and evidence-based dietary interventions. All recommendations are based on peer-reviewed research and 15+ years of clinical experience, but should not replace personalized medical advice. Always consult your healthcare provider before making changes to your health regimen, especially if you have existing conditions or take medications. Individual results may vary. This content is intended for adults 50+ interested in evidence-based health information. 93% of adults over 50 show accelerated biological aging in at least one organ system. But the 12 hallmarks driving that acceleration are not mysterious and they are not irreversible. In this video, Dr. Becker breaks down the peer-reviewed science showing how specific foods and a simple fasting window can target multiple aging mechanisms simultaneously — mitophagy, autophagy, NRF2 activation, and nitric oxide production — using nothing more than what you can find at any grocery store. 🔴 Key Topics Covered: - The 12 Hallmarks of Aging (Cell 2023 update) and how they cascade - Mitophagy activation through urolithin A from pomegranate and berries - How a 12-hour overnight fast enhances autophagy (first human trial) - Sulforaphane from broccoli sprouts activating 200+ protective genes via NRF2 - Nitric oxide production from spinach and your tongue microbiome - EGCG from green tea and the hormesis mechanism - Beans, legumes, and the Blue Zones gut microbiome connection - A complete 7-day starting protocol with specific doses and preparation methods What if the most powerful anti-aging intervention isn't an expensive supplement or experimental therapy — but what you put on your plate and when you stop eatin https://www.youtube-nocookie.com/embed/EA-lCcBKtrg 1396 2026-04-07T21:00:00.000Z 2026-10-22T19:54:19.249Z https://longevityharbor.com/en/watch/EG_7Vf2fC5w phoenix-Thema: "Gesund durch Bewegung" vom 24.10.2015 https://i.ytimg.com/vi/EG_7Vf2fC5w/hqdefault.jpg Warum Bewegung in jedem Alter so wichtig ist und was die Folgen für jeden Einzelnen, aber auch für die Gesellschaft sind, zeigt die phoenix- Sendung "Gesund durch Bewegung". Die Reporter Michael Krons und Kristian Wiegand haben sich bei Sportwissenschaftlern, Ärzten und Lehrern erkundigt wie es um das Thema Bewegung bei Kindern, Jugendlichen und Erwachsenen steht und warum man die Menschen vom Sofa holen muss. https://www.youtube-nocookie.com/embed/EG_7Vf2fC5w 4491 2015-10-27T15:20:32.000Z 2026-10-22T17:43:36.100Z https://longevityharbor.com/de/watch/EG_7Vf2fC5w phoenix-Thema: "Gesund durch Bewegung" vom 24.10.2015 https://i.ytimg.com/vi/EG_7Vf2fC5w/hqdefault.jpg Warum Bewegung in jedem Alter so wichtig ist und was die Folgen für jeden Einzelnen, aber auch für die Gesellschaft sind, zeigt die phoenix- Sendung "Gesund durch Bewegung". Die Reporter Michael Krons und Kristian Wiegand haben sich bei Sportwissenschaftlern, Ärzten und Lehrern erkundigt wie es um das Thema Bewegung bei Kindern, Jugendlichen und Erwachsenen steht und warum man die Menschen vom Sofa holen muss. https://www.youtube-nocookie.com/embed/EG_7Vf2fC5w 4491 2015-10-27T15:20:32.000Z 2026-10-22T17:43:36.100Z https://longevityharbor.com/en/watch/EHs5ghjeB5k Scientists Discovered a Fat That Reverses Aging — Here's Why No One Is Talking About It https://i.ytimg.com/vi/EHs5ghjeB5k/hqdefault.jpg Discover why C15 health benefits might outperform omega-3s for longevity. Learn how this essential nutrient supports cellular integrity. Dr. Stephanie Venn-Watson, a veterinary epidemiologist, explains the critical role of C15 in disease prevention. Many of us focus on common nutrients, yet this specific fatty acid may be the missing piece for long-term health. The video details why cellular fragility occurs without proper C15 levels and contrasts it with traditional supplements like omega-3s. We also address the rising global concerns regarding fatty liver disease, which now affects 38% of the population. Understanding these nutritional gaps is vital for anyone looking to optimize their biological aging process and maintain robust cell structures. #fattyliver #functionalmedicine Subscribe for weekly longevity science breakdowns, and comment below if you have heard of C15 before. This groundbreaking discovery could change how we think about nutrition and longevity. View Show Notes From This Episode https://drhyman.com/blogs/content/podcast-ep1019 Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast This episode is brought to you by PaleoValley, Timeline Nutrition, LMNT, BON CHARGE, and Big Bold Health. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase. Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today. Get a free LMNT Sample Pack with any order—just head to drinklmnt.com/hyman. Order BON CHARGE’s Max Red Light Therapy device today and get 15% off. Visit boncharge.com and use code DRMARK for 15% off. Try Big Bold Health’s HTB Rejuvenate and get 25% off by going to bigboldhealth.com and use code DRMARK25 at checkout. (0:00) Discovery of C15, global prevalence of fatty https://www.youtube-nocookie.com/embed/EHs5ghjeB5k 4016 2025-03-26T10:00:29.000Z 2026-10-22T19:54:19.272Z https://longevityharbor.com/de/watch/EHs5ghjeB5k Scientists Discovered a Fat That Reverses Aging — Here's Why No One Is Talking About It https://i.ytimg.com/vi/EHs5ghjeB5k/hqdefault.jpg Discover why C15 health benefits might outperform omega-3s for longevity. Learn how this essential nutrient supports cellular integrity. Dr. Stephanie Venn-Watson, a veterinary epidemiologist, explains the critical role of C15 in disease prevention. Many of us focus on common nutrients, yet this specific fatty acid may be the missing piece for long-term health. The video details why cellular fragility occurs without proper C15 levels and contrasts it with traditional supplements like omega-3s. We also address the rising global concerns regarding fatty liver disease, which now affects 38% of the population. Understanding these nutritional gaps is vital for anyone looking to optimize their biological aging process and maintain robust cell structures. #fattyliver #functionalmedicine Subscribe for weekly longevity science breakdowns, and comment below if you have heard of C15 before. This groundbreaking discovery could change how we think about nutrition and longevity. View Show Notes From This Episode https://drhyman.com/blogs/content/podcast-ep1019 Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast This episode is brought to you by PaleoValley, Timeline Nutrition, LMNT, BON CHARGE, and Big Bold Health. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase. Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today. Get a free LMNT Sample Pack with any order—just head to drinklmnt.com/hyman. Order BON CHARGE’s Max Red Light Therapy device today and get 15% off. Visit boncharge.com and use code DRMARK for 15% off. Try Big Bold Health’s HTB Rejuvenate and get 25% off by going to bigboldhealth.com and use code DRMARK25 at checkout. (0:00) Discovery of C15, global prevalence of fatty https://www.youtube-nocookie.com/embed/EHs5ghjeB5k 4016 2025-03-26T10:00:29.000Z 2026-10-22T19:54:19.272Z https://longevityharbor.com/en/watch/EIzCPLEbanQ Video description: strength training after 60 and muscle growth claims https://i.ytimg.com/vi/EIzCPLEbanQ/hqdefault.jpg The description says decades of research with older adults contradict the belief that muscle and strength cannot be built after 60. It presents strength training, activity and nutrition as ways the body can respond, and links muscle to mobility, balance, independence and quality of life. https://www.youtube-nocookie.com/embed/EIzCPLEbanQ 1412 2026-08-19T13:00:18.000Z 2026-10-22T22:54:35.256Z https://longevityharbor.com/de/watch/EIzCPLEbanQ Videobeschreibung: Krafttraining nach 60 und Aussagen zum Muskelaufbau https://i.ytimg.com/vi/EIzCPLEbanQ/hqdefault.jpg Die Beschreibung sagt, jahrzehntelange Forschung mit älteren Erwachsenen widerspreche der Annahme, dass Muskeln und Kraft nach 60 nicht mehr aufgebaut werden können. Sie nennt Krafttraining, Aktivität und Ernährung als mögliche Reize und verbindet Muskeln mit Mobilität, Gleichgewicht, Selbstständigkeit und Lebensqualität. https://www.youtube-nocookie.com/embed/EIzCPLEbanQ 1412 2026-08-19T13:00:18.000Z 2026-10-22T22:54:35.256Z https://longevityharbor.com/en/watch/ELRby2SmQQg Student lecture overview: hemostasis, cancer hallmarks and aging theories https://i.ytimg.com/vi/ELRby2SmQQg/hqdefault.jpg The description says this student-run lecture unit covers hemostasis and thrombosis, molecular cancer biology and aging biochemistry, then applies these ideas to clinical case histories. It is described as an educational summary, not a study. https://www.youtube-nocookie.com/embed/ELRby2SmQQg 1951 2025-12-29T22:12:01.000Z 2026-10-23T03:04:37.503Z https://longevityharbor.com/de/watch/ELRby2SmQQg Studentenvortrag: Hämostase, Krebsmerkmale und Alterungstheorien https://i.ytimg.com/vi/ELRby2SmQQg/hqdefault.jpg Laut Beschreibung behandelt diese von Studierenden erstellte Vorlesungseinheit Hämostase und Thrombose, molekulare Krebsbiologie und Alterungsbiochemie und wendet diese Ideen dann auf klinische Fallgeschichten an. Sie wird als Lernzusammenfassung beschrieben, nicht als Studie. https://www.youtube-nocookie.com/embed/ELRby2SmQQg 1951 2025-12-29T22:12:01.000Z 2026-10-23T03:04:37.503Z https://longevityharbor.com/en/watch/ELcVYRJJdK4 Podcast description: Charles Brenner on NAD, inflammation and NR claims https://i.ytimg.com/vi/ELcVYRJJdK4/hqdefault.jpg The description says Dr. Charles Brenner discusses how disease states disrupt NAD levels, what human data show about NAD boosters such as oral NAD pills, NMN, NR and NAD IV drips, and emerging research on NR for inflammation and recovery. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/ELcVYRJJdK4 6858 2026-02-10T16:30:07.000Z 2026-10-23T02:35:59.289Z https://longevityharbor.com/de/watch/ELcVYRJJdK4 Podcast-Beschreibung: Charles Brenner über NAD, Entzündung und NR-Aussagen https://i.ytimg.com/vi/ELcVYRJJdK4/hqdefault.jpg Laut Beschreibung erläutert Dr. Charles Brenner, wie Krankheitszustände den NAD-Spiegel stören, was menschliche Daten zu NAD-Boostern wie oralen NAD-Tabletten, NMN, NR und NAD-Infusionen zeigen und was erste Forschung zu NR bei Entzündung und Erholung nahelegt. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/ELcVYRJJdK4 6858 2026-02-10T16:30:07.000Z 2026-10-23T02:35:59.289Z https://longevityharbor.com/en/watch/EO-NlEjgYOE Video description: three experimental age-reversal approaches, from mice to planned human trials https://i.ytimg.com/vi/EO-NlEjgYOE/hqdefault.jpg The description presents three experimental approaches: blocking IL-11 extended mouse lifespan by 25%, partial reprogramming aims to make old cells young again, and senolytics target senescent cells. Human anti-aging use is not approved, and the creator notes risks. https://www.youtube-nocookie.com/embed/EO-NlEjgYOE 422 2026-01-29T21:29:37.000Z 2026-10-23T02:42:01.993Z https://longevityharbor.com/de/watch/EO-NlEjgYOE Videobeschreibung: drei experimentelle Ansätze gegen das Altern, von Mäusen bis zu geplanten Studien https://i.ytimg.com/vi/EO-NlEjgYOE/hqdefault.jpg Die Beschreibung stellt drei experimentelle Ansätze vor: IL-11-Blockade verlängerte die Lebensspanne von Mäusen um 25 %, partielles Reprogrammieren soll alte Zellen verjüngen, Senolytika zielen auf seneszente Zellen. Für den Anti-Aging-Einsatz beim Menschen ist nichts zugelassen; der Ersteller nennt Risiken. https://www.youtube-nocookie.com/embed/EO-NlEjgYOE 422 2026-01-29T21:29:37.000Z 2026-10-23T02:42:01.993Z https://longevityharbor.com/en/watch/EPjdpobvglo The Critical Reason You Need to Lift Weights as You Age | Dr. Mark Hyman https://i.ytimg.com/vi/EPjdpobvglo/hqdefault.jpg Building and maintaining muscle is a crucial way to slow down the aging process and is a key component of a healthy lifestyle. This video explains why muscle, often seen as the "organ of longevity," is essential as muscle loss significantly increases after age 30. Discover how physical activity and strength training can support muscle building and contribute to your longevity secrets. Lifting weights as you age isn't about building a bodybuilder physique—it is the ultimate biological secret to slowing down the aging process. Discover why building lean muscle is the true currency of longevity and how it protects your metabolic health, brain, and hormones. In this episode, Dr. Mark Hyman breaks down the critical reasons why resistance training is essential for everyone, especially as we get older. We are currently facing a massive metabolic health crisis driven by sedentary lifestyles and ultra-processed diets. By increasing your lean muscle mass, you can combat insulin resistance, reduce chronic inflammation, and stimulate the release of "myokines"—powerful healing molecules that actively communicate with your brain, bones, and fat tissue to keep you young. Whether you are completely new to fitness or looking to optimize your longevity routine, you'll learn the minimum viable dose of exercise needed to see transformative results. From simple bodyweight movements and daily "exercise snacks" to understanding exactly how much protein your body requires to synthesize muscle, this video gives you a practical, accessible roadmap to aging gracefully and staying functionally strong for life. Get my FREE guide 3 Steps to Reverse Aging when you sign up for my weekly health picks 👉 https://bit.ly/IncreaseHealthspan View Show Notes From This Episode: https://bit.ly/ep-951 This episode is brought to you by Mitopure, OneSkin, Seed, and AX3. Support essential mitochondrial health and save 10% on Mitopure. Visit https://TimelineNutrition.com/Drhyman and use code DRHYMAN10. Unlock your healthiest skin yet. Try OneSkin wit https://www.youtube-nocookie.com/embed/EPjdpobvglo 1388 2024-09-20T10:00:15.000Z 2026-10-22T17:43:36.936Z https://longevityharbor.com/de/watch/EPjdpobvglo The Critical Reason You Need to Lift Weights as You Age | Dr. Mark Hyman https://i.ytimg.com/vi/EPjdpobvglo/hqdefault.jpg Building and maintaining muscle is a crucial way to slow down the aging process and is a key component of a healthy lifestyle. This video explains why muscle, often seen as the "organ of longevity," is essential as muscle loss significantly increases after age 30. Discover how physical activity and strength training can support muscle building and contribute to your longevity secrets. Lifting weights as you age isn't about building a bodybuilder physique—it is the ultimate biological secret to slowing down the aging process. Discover why building lean muscle is the true currency of longevity and how it protects your metabolic health, brain, and hormones. In this episode, Dr. Mark Hyman breaks down the critical reasons why resistance training is essential for everyone, especially as we get older. We are currently facing a massive metabolic health crisis driven by sedentary lifestyles and ultra-processed diets. By increasing your lean muscle mass, you can combat insulin resistance, reduce chronic inflammation, and stimulate the release of "myokines"—powerful healing molecules that actively communicate with your brain, bones, and fat tissue to keep you young. Whether you are completely new to fitness or looking to optimize your longevity routine, you'll learn the minimum viable dose of exercise needed to see transformative results. From simple bodyweight movements and daily "exercise snacks" to understanding exactly how much protein your body requires to synthesize muscle, this video gives you a practical, accessible roadmap to aging gracefully and staying functionally strong for life. Get my FREE guide 3 Steps to Reverse Aging when you sign up for my weekly health picks 👉 https://bit.ly/IncreaseHealthspan View Show Notes From This Episode: https://bit.ly/ep-951 This episode is brought to you by Mitopure, OneSkin, Seed, and AX3. Support essential mitochondrial health and save 10% on Mitopure. Visit https://TimelineNutrition.com/Drhyman and use code DRHYMAN10. Unlock your healthiest skin yet. Try OneSkin wit https://www.youtube-nocookie.com/embed/EPjdpobvglo 1388 2024-09-20T10:00:15.000Z 2026-10-22T17:43:36.936Z https://longevityharbor.com/en/watch/EVGOtH0lSbw What are the integrative hallmarks of aging? https://i.ytimg.com/vi/EVGOtH0lSbw/hqdefault.jpg What are the causes of aging? Previously, I introduced the different hallmarks of aging; (https://youtu.be/U5ORO0IN_IM). These hallmarks can be split into three categories. In this video we will look just at the integrative hallmarks of aging, the last category, which are ultimately responsible for the functional decline in tissues which contribute to aging. This includes deregulation of intercellular signalling and loss of stem cells. Primary causes of aging; https://youtu.be/daS5WSYt5xc Antagonistic hallmarks of aging; https://youtu.be/2EOPp_veBjM The review paper; https://www.cell.com/abstract/S0092-8674(13)00645-4 Blog; asheekeyscienceblog.com https://www.youtube-nocookie.com/embed/EVGOtH0lSbw 421 2019-07-10T10:35:37.000Z 2026-10-22T17:43:40.114Z https://longevityharbor.com/de/watch/EVGOtH0lSbw What are the integrative hallmarks of aging? https://i.ytimg.com/vi/EVGOtH0lSbw/hqdefault.jpg What are the causes of aging? Previously, I introduced the different hallmarks of aging; (https://youtu.be/U5ORO0IN_IM). These hallmarks can be split into three categories. In this video we will look just at the integrative hallmarks of aging, the last category, which are ultimately responsible for the functional decline in tissues which contribute to aging. This includes deregulation of intercellular signalling and loss of stem cells. Primary causes of aging; https://youtu.be/daS5WSYt5xc Antagonistic hallmarks of aging; https://youtu.be/2EOPp_veBjM The review paper; https://www.cell.com/abstract/S0092-8674(13)00645-4 Blog; asheekeyscienceblog.com https://www.youtube-nocookie.com/embed/EVGOtH0lSbw 421 2019-07-10T10:35:37.000Z 2026-10-22T17:43:40.114Z https://longevityharbor.com/en/watch/EVV1cZZxKEo Video description: NAD⁺, NR and NMN — what human evidence shows https://i.ytimg.com/vi/EVV1cZZxKEo/hqdefault.jpg The pharmacist creator says NAD⁺ matters for cell energy, but human studies of NAD⁺ precursors show effects on NAD⁺ metabolism, not proven slowing of human ageing. https://www.youtube-nocookie.com/embed/EVV1cZZxKEo 812 2026-09-06T07:00:33.000Z 2026-10-22T22:28:19.281Z https://longevityharbor.com/de/watch/EVV1cZZxKEo Videobeschreibung: NAD⁺, NR und NMN – was Humanbelege zeigen https://i.ytimg.com/vi/EVV1cZZxKEo/hqdefault.jpg Laut der Apothekerin ist NAD⁺ wichtig für die Zellenergie; Humanstudien zu NAD⁺-Vorstufen zeigen jedoch Wirkungen auf den NAD⁺-Stoffwechsel, keine belegte Verlangsamung des menschlichen Alterns. https://www.youtube-nocookie.com/embed/EVV1cZZxKEo 812 2026-09-06T07:00:33.000Z 2026-10-22T22:28:19.281Z https://longevityharbor.com/en/watch/EXoDUjltl1Q Video description compares NAD and NMN for cellular energy and aging https://i.ytimg.com/vi/EXoDUjltl1Q/hqdefault.jpg The description says NAD and NMN both support cellular energy and aging in different ways, and that the creator will focus on the data. No results, doses or study details are given. https://www.youtube-nocookie.com/embed/EXoDUjltl1Q 109 2026-09-09T21:07:28.000Z 2026-10-22T22:23:27.937Z https://longevityharbor.com/de/watch/EXoDUjltl1Q Videobeschreibung vergleicht NAD und NMN für Zellenergie und Altern https://i.ytimg.com/vi/EXoDUjltl1Q/hqdefault.jpg Die Beschreibung sagt, NAD und NMN unterstützten beide Zellenergie und Altern auf unterschiedliche Weise, und der Ersteller wolle sich auf die Daten konzentrieren. Ergebnisse, Dosierungen oder Studiendetails fehlen. https://www.youtube-nocookie.com/embed/EXoDUjltl1Q 109 2026-09-09T21:07:28.000Z 2026-10-22T22:23:27.937Z https://longevityharbor.com/en/watch/EXzX6CjtAHc mTORC1 in Classical Monocytes: Links to Human Size Variation & Neuropsychiatric Disease | Aging-US https://i.ytimg.com/vi/EXzX6CjtAHc/hqdefault.jpg Aging-US #published this #trending research #paper on July 26, 2024 in Volume 16, Issue 14, entitled, “mTORC1 activation in presumed classical monocytes: observed correlation with human size variation and neuropsychiatric disease" by researchers from Woodinville Psychiatric Associates, Woodinville, WA; Department of Biology, Virginia Commonwealth University, Richmond, VA; Life Sciences, Virginia Commonwealth University, Richmond, VA; Institute of Cancer and Genomics Sciences, University of Birmingham, Birmingham, UK; Institute of Translational Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK; MRC Health Data Research UK (HDR UK), London, UK. @virginiacommonwealthuniversity @unibirmingham #aging #neurology #rapamycin #mTORC1 #lithium #ketaminetherapy #research #openaccess #openscience #peerreview #journal #publication #publishing #meded DOI - https://doi.org/10.18632/aging.206033 Corresponding author - Jon Berner - jonbernermd@gmail.com Abstract Background: Gain of function disturbances in nutrient sensing are likely the largest component in human age-related disease. Mammalian target of rapamycin complex 1 (mTORC1) activity affects health span and longevity. The drugs ketamine and rapamycin are effective against chronic pain and depression, and both affect mTORC1 activity. Our objective was to measure phosphorylated p70S6K, a marker for mTORC1 activity, in individuals with psychiatric disease to determine whether phosphorylated p70S6K could predict medication response. Methods: Twenty-seven females provided blood samples in which p70S6K and phosphorylated p70S6K were analyzed. Chart review gathered biometric measurements, clinical phenotypes, and medication response. Questionnaires assessed anxiety, depression, autism traits, and mitochondrial dysfunction, to determine neuropsychiatric disease profiles. Univariate and multivariate statistical analyses were used to identify predictors of medication response. Results: mTORC1 activity correlated highly with both classical biometr https://www.youtube-nocookie.com/embed/EXzX6CjtAHc 135 2024-08-06T20:06:04.000Z 2026-10-22T19:54:22.361Z https://longevityharbor.com/de/watch/EXzX6CjtAHc mTORC1 in Classical Monocytes: Links to Human Size Variation & Neuropsychiatric Disease | Aging-US https://i.ytimg.com/vi/EXzX6CjtAHc/hqdefault.jpg Aging-US #published this #trending research #paper on July 26, 2024 in Volume 16, Issue 14, entitled, “mTORC1 activation in presumed classical monocytes: observed correlation with human size variation and neuropsychiatric disease" by researchers from Woodinville Psychiatric Associates, Woodinville, WA; Department of Biology, Virginia Commonwealth University, Richmond, VA; Life Sciences, Virginia Commonwealth University, Richmond, VA; Institute of Cancer and Genomics Sciences, University of Birmingham, Birmingham, UK; Institute of Translational Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK; MRC Health Data Research UK (HDR UK), London, UK. @virginiacommonwealthuniversity @unibirmingham #aging #neurology #rapamycin #mTORC1 #lithium #ketaminetherapy #research #openaccess #openscience #peerreview #journal #publication #publishing #meded DOI - https://doi.org/10.18632/aging.206033 Corresponding author - Jon Berner - jonbernermd@gmail.com Abstract Background: Gain of function disturbances in nutrient sensing are likely the largest component in human age-related disease. Mammalian target of rapamycin complex 1 (mTORC1) activity affects health span and longevity. The drugs ketamine and rapamycin are effective against chronic pain and depression, and both affect mTORC1 activity. Our objective was to measure phosphorylated p70S6K, a marker for mTORC1 activity, in individuals with psychiatric disease to determine whether phosphorylated p70S6K could predict medication response. Methods: Twenty-seven females provided blood samples in which p70S6K and phosphorylated p70S6K were analyzed. Chart review gathered biometric measurements, clinical phenotypes, and medication response. Questionnaires assessed anxiety, depression, autism traits, and mitochondrial dysfunction, to determine neuropsychiatric disease profiles. Univariate and multivariate statistical analyses were used to identify predictors of medication response. Results: mTORC1 activity correlated highly with both classical biometr https://www.youtube-nocookie.com/embed/EXzX6CjtAHc 135 2024-08-06T20:06:04.000Z 2026-10-22T19:54:22.361Z https://longevityharbor.com/en/watch/EY9Miiu9aiI Aging "Hotspot" Found in Brain? Hypochondriacs Don't Live as Long? https://i.ytimg.com/vi/EY9Miiu9aiI/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan We explore the psychological and health implications of hypochondriasis, especially in the context of biological age testing and wearables. We then delve into how anxiety and fixation on health metrics can influence behavior and potentially exacerbate health risks. This discussion transitions to a groundbreaking study on brain aging from the Allen Institute, highlighting insights from single-cell transcriptomics, particularly inflammation and neurovascular changes as drivers of aging. Finally, we discuss practical takeaways like the importance of exercise, stress management, and environmental enrichment in promoting healthy brain aging while reflecting on broader societal impacts of health-focused influencers and diagnostics. 0:00 - Study on hypochondriasis and mortality risks 1:20 - Biological age testing and psychological implications 4:30 - Wearables and their psychological effects 6:10 - Influence of biohacking on health anxieties 8:10 - Concluding thoughts on diagnostics and anxiety 12:30 - New study on brain aging by Allen Institute 14:00 - Methodology: Single-cell transcriptomics in brain aging 16:30 - Insights on inflammation and glial cells in aging 19:45 - Implications for neurovascular interactions and aging 22:30 - Practical advice: Sleep, stress, and physical exercise 25:15 - Role of environmental enrichment in cognitive aging Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especiall https://www.youtube-nocookie.com/embed/EY9Miiu9aiI 1583 2025-01-14T15:00:14.000Z 2026-10-22T19:04:38.817Z https://longevityharbor.com/de/watch/EY9Miiu9aiI Aging "Hotspot" Found in Brain? Hypochondriacs Don't Live as Long? https://i.ytimg.com/vi/EY9Miiu9aiI/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan We explore the psychological and health implications of hypochondriasis, especially in the context of biological age testing and wearables. We then delve into how anxiety and fixation on health metrics can influence behavior and potentially exacerbate health risks. This discussion transitions to a groundbreaking study on brain aging from the Allen Institute, highlighting insights from single-cell transcriptomics, particularly inflammation and neurovascular changes as drivers of aging. Finally, we discuss practical takeaways like the importance of exercise, stress management, and environmental enrichment in promoting healthy brain aging while reflecting on broader societal impacts of health-focused influencers and diagnostics. 0:00 - Study on hypochondriasis and mortality risks 1:20 - Biological age testing and psychological implications 4:30 - Wearables and their psychological effects 6:10 - Influence of biohacking on health anxieties 8:10 - Concluding thoughts on diagnostics and anxiety 12:30 - New study on brain aging by Allen Institute 14:00 - Methodology: Single-cell transcriptomics in brain aging 16:30 - Insights on inflammation and glial cells in aging 19:45 - Implications for neurovascular interactions and aging 22:30 - Practical advice: Sleep, stress, and physical exercise 25:15 - Role of environmental enrichment in cognitive aging Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especiall https://www.youtube-nocookie.com/embed/EY9Miiu9aiI 1583 2025-01-14T15:00:14.000Z 2026-10-22T19:04:38.817Z https://longevityharbor.com/en/watch/EdjB7nV7HfY Can Fasting & Calorie Restriction Help You Live Longer? | Dr Matt Kaeberlein | The Proof Clips EP249 https://i.ytimg.com/vi/EdjB7nV7HfY/hqdefault.jpg The topic of caloric restriction and fasting and their potential to extend lifespan has been a subject of much discussion in the field of nutrition. Animal studies on mice and other animals have provided some insights into the effects of caloric restriction on longevity. However, biologist Dr Matt Kaeberlein points out, for example, that the effects of caloric restriction can vary depending on the genetic background of the animal. This suggests that the results of laboratory studies on caloric restriction may not necessarily translate to humans. In addition to caloric restriction, fasting is also a topic of interest when it comes to longevity. Can prolonged fasting help you fight ageing? Here's Dr Kaeberlein for more of what data there is if you want to understand the nuances of these dietary approaches and their potential impact on ageing. Stream the full episode on YouTube: Or listen on your favourite podcasting platform: ==== Get access to every episode 10 hours before YouTube by subscribing for free on Spotify - https://open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi or Apple Podcasts - https://podcasts.apple.com/gb/podcast/the-proof-with-simon-hill/id1367773989 ==== Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit https://theproof.com/friends/. • The Proof with Simon Hill - https://theproof.com/podcast/ • Book: The Proof is in the Plants - https://theproof.com/book/ • Apple Podcast - https://podcasts.apple.com/gb/podcast/the-proof-with-simonhill/id1367773989 • Spotify - https://open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi • Instagram - https://www.instagram.com/theproof/ • Twitter - https://twitter.com/theproof • Facebook - https://www.facebook.com/theproofwithsimonhill • Plant-Based Ferments Guide - https://theproof.com/ferments/ • Two-week meal plan - https://theproof.com/mealplan/ • Plant Performance - https://theproof.com/plant-performance/ • Use the products and services of https://www.youtube-nocookie.com/embed/EdjB7nV7HfY 1047 2023-08-18T12:00:09.000Z 2026-10-22T17:43:38.444Z https://longevityharbor.com/de/watch/EdjB7nV7HfY Can Fasting & Calorie Restriction Help You Live Longer? | Dr Matt Kaeberlein | The Proof Clips EP249 https://i.ytimg.com/vi/EdjB7nV7HfY/hqdefault.jpg The topic of caloric restriction and fasting and their potential to extend lifespan has been a subject of much discussion in the field of nutrition. Animal studies on mice and other animals have provided some insights into the effects of caloric restriction on longevity. However, biologist Dr Matt Kaeberlein points out, for example, that the effects of caloric restriction can vary depending on the genetic background of the animal. This suggests that the results of laboratory studies on caloric restriction may not necessarily translate to humans. In addition to caloric restriction, fasting is also a topic of interest when it comes to longevity. Can prolonged fasting help you fight ageing? Here's Dr Kaeberlein for more of what data there is if you want to understand the nuances of these dietary approaches and their potential impact on ageing. Stream the full episode on YouTube: Or listen on your favourite podcasting platform: ==== Get access to every episode 10 hours before YouTube by subscribing for free on Spotify - https://open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi or Apple Podcasts - https://podcasts.apple.com/gb/podcast/the-proof-with-simon-hill/id1367773989 ==== Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit https://theproof.com/friends/. • The Proof with Simon Hill - https://theproof.com/podcast/ • Book: The Proof is in the Plants - https://theproof.com/book/ • Apple Podcast - https://podcasts.apple.com/gb/podcast/the-proof-with-simonhill/id1367773989 • Spotify - https://open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi • Instagram - https://www.instagram.com/theproof/ • Twitter - https://twitter.com/theproof • Facebook - https://www.facebook.com/theproofwithsimonhill • Plant-Based Ferments Guide - https://theproof.com/ferments/ • Two-week meal plan - https://theproof.com/mealplan/ • Plant Performance - https://theproof.com/plant-performance/ • Use the products and services of https://www.youtube-nocookie.com/embed/EdjB7nV7HfY 1047 2023-08-18T12:00:09.000Z 2026-10-22T17:43:38.444Z https://longevityharbor.com/en/watch/Ef8tjt0MB4g Zombie cells: real biology, early human senolytic research https://i.ytimg.com/vi/Ef8tjt0MB4g/hqdefault.jpg The description says cellular senescence is proven biology, but that is not the same as a proven anti-aging treatment; senolytic animal studies look compelling while human research remains early. https://www.youtube-nocookie.com/embed/Ef8tjt0MB4g 108 2026-09-21T13:47:28.000Z 2026-10-22T22:02:45.839Z https://longevityharbor.com/de/watch/Ef8tjt0MB4g Zombie-Zellen: echte Biologie, frühe Senolytika-Forschung am Menschen https://i.ytimg.com/vi/Ef8tjt0MB4g/hqdefault.jpg Laut Beschreibung ist zelluläre Seneszenz belegte Biologie, aber kein belegter Anti-Aging-Behandlungserfolg; Senolytika-Studien an Tieren wirken vielversprechend, die Forschung am Menschen steht noch früh. https://www.youtube-nocookie.com/embed/Ef8tjt0MB4g 108 2026-09-21T13:47:28.000Z 2026-10-22T22:02:45.839Z https://longevityharbor.com/en/watch/EfoIaESR7sI Why "second generation" epigenetic clocks are better at detecting biological age | Dr. Morgan Levine https://i.ytimg.com/vi/EfoIaESR7sI/hqdefault.jpg When we talk about epigenetic clocks, one of the key innovations of the last few years has been the development of techniques to reduce statistical noise to make them more accurate at detecting biological age. Put another way, there is a big difference between first-generation and second-generation epigenetic clocks. The second-generation clocks go a step beyond tracking chronological age by statistically regressing more conventional health-related biomarkers. This differentiating strategy used in new epigenetic clocks, namely PhenoAge and GrimAge, may be really important in future trial design for many studies. Listen as recent podcast guest from episode 72 of the FoundMyFitness podcast, Dr. Morgan Levine, describes the importance of this step in making her epigenetic clock PhenoAge and that of her postdoctoral mentor GrimAge more accurate in their ability to detect biological age and epigenetic age acceleration. Full episode can be found here: https://youtu.be/_dOofH4PC9w https://www.youtube-nocookie.com/embed/EfoIaESR7sI 310 2022-04-13T21:37:44.000Z 2026-10-22T17:43:35.176Z https://longevityharbor.com/de/watch/EfoIaESR7sI Why "second generation" epigenetic clocks are better at detecting biological age | Dr. Morgan Levine https://i.ytimg.com/vi/EfoIaESR7sI/hqdefault.jpg When we talk about epigenetic clocks, one of the key innovations of the last few years has been the development of techniques to reduce statistical noise to make them more accurate at detecting biological age. Put another way, there is a big difference between first-generation and second-generation epigenetic clocks. The second-generation clocks go a step beyond tracking chronological age by statistically regressing more conventional health-related biomarkers. This differentiating strategy used in new epigenetic clocks, namely PhenoAge and GrimAge, may be really important in future trial design for many studies. Listen as recent podcast guest from episode 72 of the FoundMyFitness podcast, Dr. Morgan Levine, describes the importance of this step in making her epigenetic clock PhenoAge and that of her postdoctoral mentor GrimAge more accurate in their ability to detect biological age and epigenetic age acceleration. Full episode can be found here: https://youtu.be/_dOofH4PC9w https://www.youtube-nocookie.com/embed/EfoIaESR7sI 310 2022-04-13T21:37:44.000Z 2026-10-22T17:43:35.176Z https://longevityharbor.com/en/watch/EgIy0ghrDmo Off-Label Rapamycin Experiences & Doses | 7 - RF#2 https://i.ytimg.com/vi/EgIy0ghrDmo/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Check out our 3-part series with Jonathan An discussing oral health and its relationship to aging, including rapamycin's impact on oral health and periodontal disease. Part 1: https://www.youtube.com/watch?v=06kXAJNZa0A&t=335s Part 2: https://www.youtube.com/watch?v=TVJNLXQeCg0&t=294s Part 3: https://www.youtube.com/watch?v=US2aaISId1U&t=1698s The R-Files is a series of episodes about rapamycin, a naturally occurring compound originally discovered in soil samples from Easter Island, also known as Rapa Nui (hence the drug's name). Rapamycin belongs to a class of drugs called macrolides and has potent immunosuppressive and anti-proliferative effects. The drug has garnered attention for its potential anti-aging properties and has attracted research interest for its ability to extend lifespan and delay age-related diseases in various model organisms, including yeast and mice. In this second episode of the R-Files, Matt, who has spent a significant chunk of his career studying rapamycin, discusses his own journey to using rapamycin off-label and how it all began with a persistent pain in his right shoulder that a doctor suggested might take a year to resolve. Matt conducted an n=1 experiment to test whether a short course of rapamycin might improve the age-related inflammation that was the likely cause of his shoulder issue. 0:00 Trailer 0:33 Recap of the R-Files episode 1 0:50 Introduction to Matt's personal experiments with taking rapamycin off-label 2:20 How "frozen shoulder" kicked off the beginnings of Matt's rapamycin journey 7:44 How Matt decided on his rapamycin dosage 9:41 The results of Matt's first rapamycin experiment 11:15 Matt's subsequent rapamycin cycles and his current cycle 12:47 Possible benefits of short rapamycin cycles Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor https://www.youtube-nocookie.com/embed/EgIy0ghrDmo 889 2024-02-21T15:00:12.000Z 2026-10-22T19:54:22.452Z https://longevityharbor.com/de/watch/EgIy0ghrDmo Off-Label Rapamycin Experiences & Doses | 7 - RF#2 https://i.ytimg.com/vi/EgIy0ghrDmo/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Check out our 3-part series with Jonathan An discussing oral health and its relationship to aging, including rapamycin's impact on oral health and periodontal disease. Part 1: https://www.youtube.com/watch?v=06kXAJNZa0A&t=335s Part 2: https://www.youtube.com/watch?v=TVJNLXQeCg0&t=294s Part 3: https://www.youtube.com/watch?v=US2aaISId1U&t=1698s The R-Files is a series of episodes about rapamycin, a naturally occurring compound originally discovered in soil samples from Easter Island, also known as Rapa Nui (hence the drug's name). Rapamycin belongs to a class of drugs called macrolides and has potent immunosuppressive and anti-proliferative effects. The drug has garnered attention for its potential anti-aging properties and has attracted research interest for its ability to extend lifespan and delay age-related diseases in various model organisms, including yeast and mice. In this second episode of the R-Files, Matt, who has spent a significant chunk of his career studying rapamycin, discusses his own journey to using rapamycin off-label and how it all began with a persistent pain in his right shoulder that a doctor suggested might take a year to resolve. Matt conducted an n=1 experiment to test whether a short course of rapamycin might improve the age-related inflammation that was the likely cause of his shoulder issue. 0:00 Trailer 0:33 Recap of the R-Files episode 1 0:50 Introduction to Matt's personal experiments with taking rapamycin off-label 2:20 How "frozen shoulder" kicked off the beginnings of Matt's rapamycin journey 7:44 How Matt decided on his rapamycin dosage 9:41 The results of Matt's first rapamycin experiment 11:15 Matt's subsequent rapamycin cycles and his current cycle 12:47 Possible benefits of short rapamycin cycles Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor https://www.youtube-nocookie.com/embed/EgIy0ghrDmo 889 2024-02-21T15:00:12.000Z 2026-10-22T19:54:22.452Z https://longevityharbor.com/en/watch/EhAO8WhmPkA Targeting Cellular Senescence for Healthier, More Youthful Skin https://i.ytimg.com/vi/EhAO8WhmPkA/hqdefault.jpg *Save the date! Join me and Dr. Alessandra Zonari for a free webinar on July 25th 2024 and get your questions answered on all things OS-01 peptide and biological aging. Register at https://www.drkarafitzgerald.com/webinars/ I'm thrilled to be joined by Dr. Alessandra Zonari to take a deep dive into a breakthrough in skincare science that has caught my attention—OneSkin's OS-01 peptide. This episode explores how OS-01 targets cellular senescence, the core of aging, potentially transforming skin health - preserving function, not just aesthetics. I'm particularly impressed by OneSkin's commitment to rigorous research and evidence-based results. Their approach rejuvenates skin function in addition to enhancing its natural radiance, elasticity, and even its microbiome. This could be a significant advancement for individuals managing aging skin or conditions like atopic dermatitis. Throughout our discussion, we explore the scientific foundation behind OS-01 and its clinical implications and uncover how this peptide may redefine skincare protocols, offering new possibilities for healthier, more radiant skin. Whether you're a practitioner seeking innovative solutions for patients for ultrasensitive skin or dermatitis, or someone passionate about maintaining skin health, this episode promises insights that could reshape your approach to skincare. And if you’re using OneSkin, I'd be curious to hear from you. You can post a comment wherever you're listening to this or email me directly at DrKaraFitzgerald.com. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. *GUEST DETAILS* *Alessandra Zonari, PhD* OneSkin co-founder and Chief Scientific Officer, Alessandra Zonari, PhD joined the early team in 2017 dedicating her time to understanding the underlying mechanism of the aging process and developing solutions to reverse skin’s biological age. Zonari is the co-inventor of five patents and has published more than 20 peer-reviewed papers in scientific jo https://www.youtube-nocookie.com/embed/EhAO8WhmPkA 3424 2024-07-09T13:44:06.000Z 2026-10-22T18:43:13.635Z https://longevityharbor.com/de/watch/EhAO8WhmPkA Targeting Cellular Senescence for Healthier, More Youthful Skin https://i.ytimg.com/vi/EhAO8WhmPkA/hqdefault.jpg *Save the date! Join me and Dr. Alessandra Zonari for a free webinar on July 25th 2024 and get your questions answered on all things OS-01 peptide and biological aging. Register at https://www.drkarafitzgerald.com/webinars/ I'm thrilled to be joined by Dr. Alessandra Zonari to take a deep dive into a breakthrough in skincare science that has caught my attention—OneSkin's OS-01 peptide. This episode explores how OS-01 targets cellular senescence, the core of aging, potentially transforming skin health - preserving function, not just aesthetics. I'm particularly impressed by OneSkin's commitment to rigorous research and evidence-based results. Their approach rejuvenates skin function in addition to enhancing its natural radiance, elasticity, and even its microbiome. This could be a significant advancement for individuals managing aging skin or conditions like atopic dermatitis. Throughout our discussion, we explore the scientific foundation behind OS-01 and its clinical implications and uncover how this peptide may redefine skincare protocols, offering new possibilities for healthier, more radiant skin. Whether you're a practitioner seeking innovative solutions for patients for ultrasensitive skin or dermatitis, or someone passionate about maintaining skin health, this episode promises insights that could reshape your approach to skincare. And if you’re using OneSkin, I'd be curious to hear from you. You can post a comment wherever you're listening to this or email me directly at DrKaraFitzgerald.com. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. *GUEST DETAILS* *Alessandra Zonari, PhD* OneSkin co-founder and Chief Scientific Officer, Alessandra Zonari, PhD joined the early team in 2017 dedicating her time to understanding the underlying mechanism of the aging process and developing solutions to reverse skin’s biological age. Zonari is the co-inventor of five patents and has published more than 20 peer-reviewed papers in scientific jo https://www.youtube-nocookie.com/embed/EhAO8WhmPkA 3424 2024-07-09T13:44:06.000Z 2026-10-22T18:43:13.635Z https://longevityharbor.com/en/watch/EimdDleZzBw ER Doctor's Video Description: Autophagy, Fasting, Exercise and Sleep https://i.ytimg.com/vi/EimdDleZzBw/hqdefault.jpg In this video description, Dr. Joanette says autophagy lets cells recycle damaged proteins and worn-out mitochondria, that it slows with age, and that exercise and sleep help keep it active. She says more fasting is not always better and that extreme fasting is no shortcut. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/EimdDleZzBw 805 2026-10-07T22:00:40.000Z 2026-10-22T21:01:27.504Z https://longevityharbor.com/de/watch/EimdDleZzBw Video-Beschreibung einer Notärztin: Autophagie, Fasten, Bewegung und Schlaf https://i.ytimg.com/vi/EimdDleZzBw/hqdefault.jpg In dieser Videobeschreibung sagt Dr. Joanette, Autophagie lasse Zellen beschädigte Proteine und verbrauchte Mitochondrien recyceln, sie nehme mit dem Alter ab, und Bewegung sowie Schlaf hielten sie aktiv. Mehr Fasten sei nicht immer besser, und extremes Fasten sei keine Abkürzung. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/EimdDleZzBw 805 2026-10-07T22:00:40.000Z 2026-10-22T21:01:27.504Z https://longevityharbor.com/en/watch/EjwWJj_ATnk SENIORS, These 5 Exercises Are REVERSING Aging After 60! | Barbara O'Neill https://i.ytimg.com/vi/EjwWJj_ATnk/hqdefault.jpg SENIORS, These 5 Exercises Are REVERSING Aging After 60! | Barbara O'Neill Are your daily walks not giving the results you hoped for? Discover 5 powerful exercises Barbara O’Neill recommends to reverse signs of aging naturally—especially after 60. 🌿 Join our exclusive holistic health community for weekly remedies, healing guides, and more: https://www.youtube.com/channel/UCDlA5KUmxutDx7YkLpzAPlQ/join The Best Seller Natural Healing Book!👇 https://bit.ly/4hABscP In this video, Barbara O’Neill shares her top 5 functional movement exercises proven to improve joint health, strengthen bones, and boost energy in older adults. These exercises go far beyond walking in delivering real anti-aging results—without the need for a gym or expensive equipment. If you're over 60 and serious about living longer and stronger, this is a must-watch. Watch until the end to see how these movements support better circulation, posture, and longevity. ► If you enjoy this video, please like it and share it to support our channel! ► Don’t forget to subscribe to this channel for more updates! ► Subscribe now: https://www.youtube.com/@Eternal-Health?sub_confirmation=1 ⭐WATCH OUR OTHER VIDEOS OF BARBARA O'NEILL!⭐ https://www.youtube.com/playlist?list=PL4YEGpPsJbTOeChpjN7P-XvGlsXdxf1PJ Disclaimer: Our YouTube channel offers informational content only. It is not a substitute for professional medical advice. Viewers are urged to consult healthcare professionals for personalized guidance. We do not endorse specific products or treatments. Any actions based on our content are at your own risk. Copyright Notice: All content on this YouTube channel, including but not limited to videos, graphics, and text, is protected by copyright law. Any unauthorized reproduction, distribution, or modification of our content is strictly prohibited and may result in legal action. All rights reserved by Eternal Health. Related Keywords: Barbara O’Neill anti-aging, Barbara O’Neill exercises, Barbara O’Neill over 60 health, Barbara O’Neill natural strengt https://www.youtube-nocookie.com/embed/EjwWJj_ATnk 1253 2025-11-27T17:39:43.000Z 2026-10-22T17:43:36.920Z https://longevityharbor.com/de/watch/EjwWJj_ATnk SENIORS, These 5 Exercises Are REVERSING Aging After 60! | Barbara O'Neill https://i.ytimg.com/vi/EjwWJj_ATnk/hqdefault.jpg SENIORS, These 5 Exercises Are REVERSING Aging After 60! | Barbara O'Neill Are your daily walks not giving the results you hoped for? Discover 5 powerful exercises Barbara O’Neill recommends to reverse signs of aging naturally—especially after 60. 🌿 Join our exclusive holistic health community for weekly remedies, healing guides, and more: https://www.youtube.com/channel/UCDlA5KUmxutDx7YkLpzAPlQ/join The Best Seller Natural Healing Book!👇 https://bit.ly/4hABscP In this video, Barbara O’Neill shares her top 5 functional movement exercises proven to improve joint health, strengthen bones, and boost energy in older adults. These exercises go far beyond walking in delivering real anti-aging results—without the need for a gym or expensive equipment. If you're over 60 and serious about living longer and stronger, this is a must-watch. Watch until the end to see how these movements support better circulation, posture, and longevity. ► If you enjoy this video, please like it and share it to support our channel! ► Don’t forget to subscribe to this channel for more updates! ► Subscribe now: https://www.youtube.com/@Eternal-Health?sub_confirmation=1 ⭐WATCH OUR OTHER VIDEOS OF BARBARA O'NEILL!⭐ https://www.youtube.com/playlist?list=PL4YEGpPsJbTOeChpjN7P-XvGlsXdxf1PJ Disclaimer: Our YouTube channel offers informational content only. It is not a substitute for professional medical advice. Viewers are urged to consult healthcare professionals for personalized guidance. We do not endorse specific products or treatments. Any actions based on our content are at your own risk. Copyright Notice: All content on this YouTube channel, including but not limited to videos, graphics, and text, is protected by copyright law. Any unauthorized reproduction, distribution, or modification of our content is strictly prohibited and may result in legal action. All rights reserved by Eternal Health. Related Keywords: Barbara O’Neill anti-aging, Barbara O’Neill exercises, Barbara O’Neill over 60 health, Barbara O’Neill natural strengt https://www.youtube-nocookie.com/embed/EjwWJj_ATnk 1253 2025-11-27T17:39:43.000Z 2026-10-22T17:43:36.920Z https://longevityharbor.com/en/watch/EuTpHrJMmgM Video description: epigenetic clocks and biological versus chronological age https://i.ytimg.com/vi/EuTpHrJMmgM/hqdefault.jpg The description says the video explains epigenetic clocks, from DNA methylation and Horvath's first clocks to GrimAge and DunedinPACE, and asks whether lifestyle can change biological age. https://www.youtube-nocookie.com/embed/EuTpHrJMmgM 242 2026-09-05T18:07:43.000Z 2026-10-22T22:28:27.037Z https://longevityharbor.com/de/watch/EuTpHrJMmgM Videobeschreibung: epigenetische Uhren und biologisches versus chronologisches Alter https://i.ytimg.com/vi/EuTpHrJMmgM/hqdefault.jpg Laut Beschreibung erklärt das Video epigenetische Uhren – von DNA-Methylierung und Horvaths ersten Uhren bis GrimAge und DunedinPACE – und fragt, ob der Lebensstil das biologische Alter verändern kann. https://www.youtube-nocookie.com/embed/EuTpHrJMmgM 242 2026-09-05T18:07:43.000Z 2026-10-22T22:28:27.037Z https://longevityharbor.com/en/watch/EuoJ5uyFt7s Caloric Restriction vs. Intermittent Fasting: Lifespan Insights https://i.ytimg.com/vi/EuoJ5uyFt7s/hqdefault.jpg Geneticist Dr. Gary Churchill talks about how dietary interventions like caloric restriction and intermittent fasting affect mouse lifespan and health. Discover surprising differences in body composition and how environment impacts longevity. Video clip from this podcast episode: https://mindandmatter.substack.com/p/calorie-restriction-and-fasting-aging #Diet #IntermittentFasting #Nutrition #Health #Lifespan #WeightLoss #Longevity #Biology #Metabolism #Science #Podcast https://www.youtube-nocookie.com/embed/EuoJ5uyFt7s 179 2024-10-21T18:03:35.000Z 2026-10-22T18:54:06.937Z https://longevityharbor.com/de/watch/EuoJ5uyFt7s Caloric Restriction vs. Intermittent Fasting: Lifespan Insights https://i.ytimg.com/vi/EuoJ5uyFt7s/hqdefault.jpg Geneticist Dr. Gary Churchill talks about how dietary interventions like caloric restriction and intermittent fasting affect mouse lifespan and health. Discover surprising differences in body composition and how environment impacts longevity. Video clip from this podcast episode: https://mindandmatter.substack.com/p/calorie-restriction-and-fasting-aging #Diet #IntermittentFasting #Nutrition #Health #Lifespan #WeightLoss #Longevity #Biology #Metabolism #Science #Podcast https://www.youtube-nocookie.com/embed/EuoJ5uyFt7s 179 2024-10-21T18:03:35.000Z 2026-10-22T18:54:06.937Z https://longevityharbor.com/en/watch/EvUHfHk0MI4 The Hallmarks of Aging That Actually Matter Most #shorts https://i.ytimg.com/vi/EvUHfHk0MI4/hqdefault.jpg Mitochondrial dysfunction. Mitochondria are the batteries inside your cells, and over time they wear out. But it's not just wear and tear, they also produce free radicals that damage cell membranes and DNA (both nuclear and mitochondrial). When DNA gets damaged, it's like the instructions inside your cells become blurry. The "workers" reading those instructions start making mistakes. This is called epigenetic drift, and it's one of the biggest areas of research we focus on in regenerative medicine, specifically epigenetic reprogramming: how do we make a cell remember its original job? This connects to the information theory of aging, a concept David Sinclair pioneered, which proposes that cells essentially lose their identity over time. Altered intercellular communication. As cells age, they stop communicating with each other properly, which compounds the damage over time. Chronic inflammation (SASP). Senescence-associated secretory phenotype is the technical term, but simply put: your body accumulates "zombie cells" it can't clear out, and these cells release inflammatory signals that create a feedback loop of chronic inflammation. Immunosenescence. Your immune system wears out too, and that's another major driver of chronic inflammation as you age. Understanding these root mechanisms is the foundation of aging well, not just living longer, but living with real vigor and vitality. #HallmarksOfAging #Longevity #EpigeneticReprogramming #RegenerativeMedicine #EternaHealth #shorts https://www.youtube-nocookie.com/embed/EvUHfHk0MI4 115 2026-10-03T04:31:59.000Z 2026-10-22T17:43:39.296Z https://longevityharbor.com/de/watch/EvUHfHk0MI4 The Hallmarks of Aging That Actually Matter Most #shorts https://i.ytimg.com/vi/EvUHfHk0MI4/hqdefault.jpg Mitochondrial dysfunction. Mitochondria are the batteries inside your cells, and over time they wear out. But it's not just wear and tear, they also produce free radicals that damage cell membranes and DNA (both nuclear and mitochondrial). When DNA gets damaged, it's like the instructions inside your cells become blurry. The "workers" reading those instructions start making mistakes. This is called epigenetic drift, and it's one of the biggest areas of research we focus on in regenerative medicine, specifically epigenetic reprogramming: how do we make a cell remember its original job? This connects to the information theory of aging, a concept David Sinclair pioneered, which proposes that cells essentially lose their identity over time. Altered intercellular communication. As cells age, they stop communicating with each other properly, which compounds the damage over time. Chronic inflammation (SASP). Senescence-associated secretory phenotype is the technical term, but simply put: your body accumulates "zombie cells" it can't clear out, and these cells release inflammatory signals that create a feedback loop of chronic inflammation. Immunosenescence. Your immune system wears out too, and that's another major driver of chronic inflammation as you age. Understanding these root mechanisms is the foundation of aging well, not just living longer, but living with real vigor and vitality. #HallmarksOfAging #Longevity #EpigeneticReprogramming #RegenerativeMedicine #EternaHealth #shorts https://www.youtube-nocookie.com/embed/EvUHfHk0MI4 115 2026-10-03T04:31:59.000Z 2026-10-22T17:43:39.296Z https://longevityharbor.com/en/watch/ExbcdFsw4_A Dave Asprey describes biohacking, mitochondria and personalized longevity ideas https://i.ytimg.com/vi/ExbcdFsw4_A/hqdefault.jpg In this conversation description, Dave Asprey links his own health struggles to decades of self-experimentation and presents biohacking as intentionally changing your state, with mitochondria, gene therapy and personalized testing discussed as topics. https://www.youtube-nocookie.com/embed/ExbcdFsw4_A 3272 2026-09-14T14:16:37.000Z 2026-10-22T22:12:30.118Z https://longevityharbor.com/de/watch/ExbcdFsw4_A Dave Asprey beschreibt Biohacking, Mitochondrien und personalisierte Langlebigkeitsideen https://i.ytimg.com/vi/ExbcdFsw4_A/hqdefault.jpg In dieser Gesprächsbeschreibung verbindet Dave Asprey eigene Gesundheitsprobleme mit jahrzehntelanger Selbstexperimentierung und beschreibt Biohacking als absichtliche Zustandsänderung; Mitochondrien, Gentherapie und personalisierte Tests werden als Themen genannt. https://www.youtube-nocookie.com/embed/ExbcdFsw4_A 3272 2026-09-14T14:16:37.000Z 2026-10-22T22:12:30.118Z https://longevityharbor.com/en/watch/EyiM72ZkEzU The Science of Sleep: 4 Proven Hacks to Reset Your Circadian Rhythm & Sleep Better Tonight https://i.ytimg.com/vi/EyiM72ZkEzU/hqdefault.jpg Struggling to get deep, restorative sleep? You're about to discover the science behind true rest! 😴 This video breaks down your body’s sleep mechanisms—the **Circadian Rhythm** and the **90-Minute Sleep Cycle**—and gives you four immediate, proven strategies to fall asleep faster and stay asleep longer. Whether you deal with mild insomnia or just want to boost your energy, these science-backed techniques are your complete 24-hour sleep recipe! **⏰ What You Will Learn in This Complete Guide:** ➡️ **Part 1: Your Brain's Rhythm (01:05)** • How the sleep cycle works and why light exposure is key. • Understanding the critical difference between deep sleep and REM sleep. ➡️ **Part 2: The 24-Hour Sleep Recipe (02:30)** • Your Daytime Toolkit: Strategies for exercise, eating habits, and the hard cut-off rule for caffeine. • Discovering the perfect room temperature for maximum sleep quality (03:15). ➡️ **Part 3: Emergency Techniques (04:07)** • The "Do This / Not That" guide for pre-sleep routines (why phones are forbidden!). • Simple hacks for when you wake up: Mastering the **4-7-8 Breathing** technique (04:40) and the **Military Sleep Method** (05:01). ➡️ **Part 4: Long-Term Success (05:26)** • Recommended sleep hours by age group (05:39) and building sustainable sleep habits. **Achieving excellent sleep starts today!** Use these science-based tips to transform your nightly routine and wake up ready for a great day. 👍 If this video helped you conquer restless nights, please give it a LIKE and SUBSCRIBE for more easy-to-understand health and science guides! https://www.youtube-nocookie.com/embed/EyiM72ZkEzU 393 2025-10-29T05:14:53.000Z 2026-10-22T19:21:25.383Z https://longevityharbor.com/de/watch/EyiM72ZkEzU The Science of Sleep: 4 Proven Hacks to Reset Your Circadian Rhythm & Sleep Better Tonight https://i.ytimg.com/vi/EyiM72ZkEzU/hqdefault.jpg Struggling to get deep, restorative sleep? You're about to discover the science behind true rest! 😴 This video breaks down your body’s sleep mechanisms—the **Circadian Rhythm** and the **90-Minute Sleep Cycle**—and gives you four immediate, proven strategies to fall asleep faster and stay asleep longer. Whether you deal with mild insomnia or just want to boost your energy, these science-backed techniques are your complete 24-hour sleep recipe! **⏰ What You Will Learn in This Complete Guide:** ➡️ **Part 1: Your Brain's Rhythm (01:05)** • How the sleep cycle works and why light exposure is key. • Understanding the critical difference between deep sleep and REM sleep. ➡️ **Part 2: The 24-Hour Sleep Recipe (02:30)** • Your Daytime Toolkit: Strategies for exercise, eating habits, and the hard cut-off rule for caffeine. • Discovering the perfect room temperature for maximum sleep quality (03:15). ➡️ **Part 3: Emergency Techniques (04:07)** • The "Do This / Not That" guide for pre-sleep routines (why phones are forbidden!). • Simple hacks for when you wake up: Mastering the **4-7-8 Breathing** technique (04:40) and the **Military Sleep Method** (05:01). ➡️ **Part 4: Long-Term Success (05:26)** • Recommended sleep hours by age group (05:39) and building sustainable sleep habits. **Achieving excellent sleep starts today!** Use these science-based tips to transform your nightly routine and wake up ready for a great day. 👍 If this video helped you conquer restless nights, please give it a LIKE and SUBSCRIBE for more easy-to-understand health and science guides! https://www.youtube-nocookie.com/embed/EyiM72ZkEzU 393 2025-10-29T05:14:53.000Z 2026-10-22T19:21:25.383Z https://longevityharbor.com/en/watch/F-h1iRSkv7k Video description: protein, leg strength and healthy aging claims https://i.ytimg.com/vi/F-h1iRSkv7k/hqdefault.jpg The description presents protein as a guide to muscle building, leg strength, mobility and longevity, and announces a protein power-bowl recipe. It cites three review papers but reports no study results. https://www.youtube-nocookie.com/embed/F-h1iRSkv7k 457 2026-09-29T11:00:39.000Z 2026-10-22T21:39:04.373Z https://longevityharbor.com/de/watch/F-h1iRSkv7k Videobeschreibung: Protein-, Beinkraft- und Alternsaussagen https://i.ytimg.com/vi/F-h1iRSkv7k/hqdefault.jpg Die Beschreibung stellt Protein als Leitfaden für Muskelaufbau, Beinkraft, Mobilität und Langlebigkeit vor und kündigt ein Protein-Power-Bowl-Rezept an. Sie nennt drei Übersichtsarbeiten, berichtet aber keine Studienergebnisse. https://www.youtube-nocookie.com/embed/F-h1iRSkv7k 457 2026-09-29T11:00:39.000Z 2026-10-22T21:39:04.373Z https://longevityharbor.com/en/watch/F6UKqKdLdjM “Medical malpractice”: Matt Kaeberlein on biological age tests https://i.ytimg.com/vi/F6UKqKdLdjM/hqdefault.jpg One idea I’ve had lately is to put together a list of people to trust in geroscience and the longevity field more broadly. (And I might do it - keep an eye on reachlevity.com - and subscribe while you’re at it!) Matt Kaeberlein would not only make that list - he’d likely be right at the top. He’s rigorous, precise in his wording, and always puts integrity ahead of hype. But, and this is important, I wouldn’t characterize him as a skeptic. He’s a realist who insists on evidence, yet at the same time he’s visionary and deeply optimistic about what aging science can deliver. Matt is probably best known for his pioneering work on rapamycin and for co-founding the Dog Aging Project. In this episode, though, we also talk about Optispan - his proactive healthcare company - and Ora Biomedical, where the WormBot platform is screening thousands of interventions for effects on lifespan. We get into therapeutic plasma exchange (TPE), how artificial intelligence might accelerate discovery, and even his favorite science fiction books. And true to form, Matt doesn’t hold back. He calls out irresponsible use of biological age tests - going so far as to label it “medical malpractice” - and criticizes hype-driven actors, sloppy science communication, and the inertia of institutions like the NIH. At the same time, he shows how rigorous, honest work could move the entire field forward. ----- Check out Matt's Youtube channel: @optispan ----- 👋🏼 Want to show your support? Subscribe to our channel, hit the notification bell and/or send us a Super Thanks! 👋🏼👋🏼👋🏼 Want to show your support and get some extra perks? Become a member! https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA/join 🚀 Special offer for our LEVITY audience: Join Vitalism today and receive a 30% discount on your membership using the code LEVITY at checkout. https://www.vitalism.io/membership Show notes for this episode will be available soon after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: reachlevity.com https://www.youtube-nocookie.com/embed/F6UKqKdLdjM 6608 2025-09-23T16:00:35.000Z 2026-10-22T19:32:34.532Z https://longevityharbor.com/de/watch/F6UKqKdLdjM “Medical malpractice”: Matt Kaeberlein on biological age tests https://i.ytimg.com/vi/F6UKqKdLdjM/hqdefault.jpg One idea I’ve had lately is to put together a list of people to trust in geroscience and the longevity field more broadly. (And I might do it - keep an eye on reachlevity.com - and subscribe while you’re at it!) Matt Kaeberlein would not only make that list - he’d likely be right at the top. He’s rigorous, precise in his wording, and always puts integrity ahead of hype. But, and this is important, I wouldn’t characterize him as a skeptic. He’s a realist who insists on evidence, yet at the same time he’s visionary and deeply optimistic about what aging science can deliver. Matt is probably best known for his pioneering work on rapamycin and for co-founding the Dog Aging Project. In this episode, though, we also talk about Optispan - his proactive healthcare company - and Ora Biomedical, where the WormBot platform is screening thousands of interventions for effects on lifespan. We get into therapeutic plasma exchange (TPE), how artificial intelligence might accelerate discovery, and even his favorite science fiction books. And true to form, Matt doesn’t hold back. He calls out irresponsible use of biological age tests - going so far as to label it “medical malpractice” - and criticizes hype-driven actors, sloppy science communication, and the inertia of institutions like the NIH. At the same time, he shows how rigorous, honest work could move the entire field forward. ----- Check out Matt's Youtube channel: @optispan ----- 👋🏼 Want to show your support? Subscribe to our channel, hit the notification bell and/or send us a Super Thanks! 👋🏼👋🏼👋🏼 Want to show your support and get some extra perks? Become a member! https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA/join 🚀 Special offer for our LEVITY audience: Join Vitalism today and receive a 30% discount on your membership using the code LEVITY at checkout. https://www.vitalism.io/membership Show notes for this episode will be available soon after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: reachlevity.com https://www.youtube-nocookie.com/embed/F6UKqKdLdjM 6608 2025-09-23T16:00:35.000Z 2026-10-22T19:32:34.532Z https://longevityharbor.com/en/watch/FDD3SxDFb3k Interview on lifespan versus healthspan, aging hallmarks and longevity strategies https://i.ytimg.com/vi/FDD3SxDFb3k/hqdefault.jpg In this interview description, internist Dr. Christopher Keroack discusses extending healthy years rather than lifespan alone, covering aging hallmarks, lifestyle pillars, selected supplements, peptides and practical biomarkers; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/FDD3SxDFb3k 3306 2025-12-05T12:00:36.000Z 2026-10-23T03:22:02.243Z https://longevityharbor.com/de/watch/FDD3SxDFb3k Interview zu Lebensspanne versus Gesundheitsspanne, Alternsmerkmalen und Longevity-Strategien https://i.ytimg.com/vi/FDD3SxDFb3k/hqdefault.jpg In dieser Interviewbeschreibung spricht Internist Dr. Christopher Keroack darüber, gesunde Jahre statt nur die Lebensspanne zu verlängern, und behandelt Alternsmerkmale, Lebensstilsäulen, ausgewählte Supplemente, Peptide und praktische Biomarker; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/FDD3SxDFb3k 3306 2025-12-05T12:00:36.000Z 2026-10-23T03:22:02.243Z https://longevityharbor.com/en/watch/FDz5HqJptMw Add 12 Years to Your Life with Simple Biohacks - Siim Land https://i.ytimg.com/vi/FDz5HqJptMw/hqdefault.jpg Diet and lifestyle hacks for building muscle, improving health and living longer. “Only 12 percent of Americans are considered metabolically healthy. In actual peak health, the percentage is probably 5 or 6%.” -Siim Land We might be living longer, but those extra years aren’t spent in good health - we’re sicker than ever. Longevity is meant to be about quantity AND quality. So how do you get both? Siim Land is a biohacker and bestselling author of eight books on health and longevity, including Stronger By Stress and Metabolic Authophagy. If you want a complete rundown of the food, the exercise and the lifestyle changes you need to live longer and happier, Siim’s your man. In this episode, he explores the impact of muscle strength, VO2 max and sprinting on ageing. He explains what metabolic autophagy is, why it’s considered the “new hallmark of ageing”, and what you can do to manipulate it. And he explores the hidden dangers of overtraining, why diet choices are more important than specific foods, and why sprinting is a superpower for longevity. Highlights 0:00 Intro 1:45 Sparking Siim’s interest in longevity 6:14 How to lift weights for a longer life 15:11 Siim’s elite level VO2 max 22:35 Why sprinting is powerful for longevity 27:13 Siim’s 8 bestsellers 31:18 What is metabolic autophagy? 34:22 Supplements and exercises that increase autophagy 37:06 A metabolically unhealthy world 38:20 Fasting for longevity 46:19 Diet choices for longevity 53:06 5 diet hacks for weight loss Visit: https://www.siimland.co/ Check out: Siim’s YouTube channel: https://www.youtube.com/c/siimland Big thanks to this episode’s sponsor, Nuzest! Their Good Green Vitality multi-nutrient drink mix supports your nervous system, immunity, cognition, energy production, and digestion. Go to https://nuzest.com and be sure to use code TIMBIOHACKER at checkout to get 25% off your first purchase of Good Green Vitality. This is the Health Optimisation Podcast with your host, Tim Gray, the UK's Leading Biohacker. This podcast brings you the https://www.youtube-nocookie.com/embed/FDz5HqJptMw 3503 2024-06-19T12:15:53.000Z 2026-10-22T19:04:37.421Z https://longevityharbor.com/de/watch/FDz5HqJptMw Add 12 Years to Your Life with Simple Biohacks - Siim Land https://i.ytimg.com/vi/FDz5HqJptMw/hqdefault.jpg Diet and lifestyle hacks for building muscle, improving health and living longer. “Only 12 percent of Americans are considered metabolically healthy. In actual peak health, the percentage is probably 5 or 6%.” -Siim Land We might be living longer, but those extra years aren’t spent in good health - we’re sicker than ever. Longevity is meant to be about quantity AND quality. So how do you get both? Siim Land is a biohacker and bestselling author of eight books on health and longevity, including Stronger By Stress and Metabolic Authophagy. If you want a complete rundown of the food, the exercise and the lifestyle changes you need to live longer and happier, Siim’s your man. In this episode, he explores the impact of muscle strength, VO2 max and sprinting on ageing. He explains what metabolic autophagy is, why it’s considered the “new hallmark of ageing”, and what you can do to manipulate it. And he explores the hidden dangers of overtraining, why diet choices are more important than specific foods, and why sprinting is a superpower for longevity. Highlights 0:00 Intro 1:45 Sparking Siim’s interest in longevity 6:14 How to lift weights for a longer life 15:11 Siim’s elite level VO2 max 22:35 Why sprinting is powerful for longevity 27:13 Siim’s 8 bestsellers 31:18 What is metabolic autophagy? 34:22 Supplements and exercises that increase autophagy 37:06 A metabolically unhealthy world 38:20 Fasting for longevity 46:19 Diet choices for longevity 53:06 5 diet hacks for weight loss Visit: https://www.siimland.co/ Check out: Siim’s YouTube channel: https://www.youtube.com/c/siimland Big thanks to this episode’s sponsor, Nuzest! Their Good Green Vitality multi-nutrient drink mix supports your nervous system, immunity, cognition, energy production, and digestion. Go to https://nuzest.com and be sure to use code TIMBIOHACKER at checkout to get 25% off your first purchase of Good Green Vitality. This is the Health Optimisation Podcast with your host, Tim Gray, the UK's Leading Biohacker. This podcast brings you the https://www.youtube-nocookie.com/embed/FDz5HqJptMw 3503 2024-06-19T12:15:53.000Z 2026-10-22T19:04:37.421Z https://longevityharbor.com/en/watch/FLWjEkAAffs Video description: muscle mass and strength training for women from age 30 https://i.ytimg.com/vi/FLWjEkAAffs/hqdefault.jpg The description says muscle mass and strength change from age 30 and asks whether this automatically means muscle loss; it presents strength training and movement as important for women from 30, and especially from midlife. https://www.youtube-nocookie.com/embed/FLWjEkAAffs 93 2026-09-01T05:49:08.000Z 2026-10-22T22:35:49.949Z https://longevityharbor.com/de/watch/FLWjEkAAffs Videobeschreibung: Muskelmasse und Krafttraining für Frauen ab 30 https://i.ytimg.com/vi/FLWjEkAAffs/hqdefault.jpg Die Beschreibung sagt, dass sich Muskelmasse und Muskelkraft ab dem 30. Lebensjahr verändern, und fragt, ob das automatisch Muskelschwund bedeutet; Krafttraining und Bewegung werden für Frauen ab 30 und besonders ab der Lebensmitte als wichtig dargestellt. https://www.youtube-nocookie.com/embed/FLWjEkAAffs 93 2026-09-01T05:49:08.000Z 2026-10-22T22:35:49.949Z https://longevityharbor.com/en/watch/FNobqZc2Tpg Seminar on single-cell and spatial transcriptomics for cellular senescence heterogeneity https://i.ytimg.com/vi/FNobqZc2Tpg/hqdefault.jpg According to the description, Dr. Nicola Neretti of Brown University presents a seminar on resolving heterogeneity of cellular senescence with single-cell and spatial transcriptomics. The description gives only the topic and speaker, not methods or results. https://www.youtube-nocookie.com/embed/FNobqZc2Tpg 3163 2026-03-11T19:43:50.000Z 2026-10-23T02:09:48.984Z https://longevityharbor.com/de/watch/FNobqZc2Tpg Seminar zu Einzelzell- und räumlicher Transkriptomik bei Heterogenität zellulärer Seneszenz https://i.ytimg.com/vi/FNobqZc2Tpg/hqdefault.jpg Laut Beschreibung hält Dr. Nicola Neretti von der Brown University ein Seminar darüber, wie sich die Heterogenität zellulärer Seneszenz mit Einzelzell- und räumlicher Transkriptomik auflösen lässt. Die Beschreibung nennt nur Thema und Vortragende, keine Methoden oder Ergebnisse. https://www.youtube-nocookie.com/embed/FNobqZc2Tpg 3163 2026-03-11T19:43:50.000Z 2026-10-23T02:09:48.984Z https://longevityharbor.com/en/watch/FPxyy485kms Valter Longo describes fasting-mimicking diets and longevity research https://i.ytimg.com/vi/FPxyy485kms/hqdefault.jpg In this video description, Longo discusses fasting-mimicking diets, caloric restriction and protein, and distinguishes short-term marker changes from long-term health. https://www.youtube-nocookie.com/embed/FPxyy485kms 2698 2026-07-27T08:00:06.000Z 2026-10-22T23:21:02.637Z https://longevityharbor.com/de/watch/FPxyy485kms Valter Longo beschreibt Fasten-imitierende Diäten und Langlebigkeitsforschung https://i.ytimg.com/vi/FPxyy485kms/hqdefault.jpg In dieser Videobeschreibung erörtert Longo Fasten-imitierende Diäten, Kalorienrestriktion und Protein und trennt kurzfristige Markerveränderungen von langfristiger Gesundheit. https://www.youtube-nocookie.com/embed/FPxyy485kms 2698 2026-07-27T08:00:06.000Z 2026-10-22T23:21:02.637Z https://longevityharbor.com/en/watch/FQRVsWPuWz0 NMN Deep Dive - What's New, What's Next, Is it Safe ? | LIFE IS LONG TALK Vol.1 https://i.ytimg.com/vi/FQRVsWPuWz0/hqdefault.jpg As interest in health and anti-aging grows, "NMN (Nicotinamide Mononucleotide)" is an ingredient that has been gathering significant attention. However, obtaining accurate information about its actual effects, safety, and how to choose the right products remains difficult. This episode delivers an easy-to-understand audio summary of the key points from "NMN Deep Dive: What's New, What's Next, Is it Safe? " a webinar conducted by scientists at NOMON & Co. The summary has been reconstructed by generative AI. ▼ What You'll Learn in This Episode ・What is NMN? We explain its fundamental mechanism and the role it plays within the body. ・The Forefront of Aging Research What have we learned from the latest studies? We explore the potential benefits and scientific evidence. ・Quality Control Issues and Tips for Product Selection The market is flooded with NMN supplements. We explain important points consumers need to know—such as purity and manufacturing methods—to distinguish safe, high-quality products. *This audio and description were summarized and created by generative AI based on the original webinar content. The content is for academic and informational purposes only. It is not intended to recommend the purchase of specific products, nor is it intended for the diagnosis, treatment, or prevention of any disease. Please consult a physician or qualified specialist when making any health-related decisions. https://www.youtube-nocookie.com/embed/FQRVsWPuWz0 754 2025-11-13T04:54:22.000Z 2026-10-22T19:04:43.018Z https://longevityharbor.com/de/watch/FQRVsWPuWz0 NMN Deep Dive - What's New, What's Next, Is it Safe ? | LIFE IS LONG TALK Vol.1 https://i.ytimg.com/vi/FQRVsWPuWz0/hqdefault.jpg As interest in health and anti-aging grows, "NMN (Nicotinamide Mononucleotide)" is an ingredient that has been gathering significant attention. However, obtaining accurate information about its actual effects, safety, and how to choose the right products remains difficult. This episode delivers an easy-to-understand audio summary of the key points from "NMN Deep Dive: What's New, What's Next, Is it Safe? " a webinar conducted by scientists at NOMON & Co. The summary has been reconstructed by generative AI. ▼ What You'll Learn in This Episode ・What is NMN? We explain its fundamental mechanism and the role it plays within the body. ・The Forefront of Aging Research What have we learned from the latest studies? We explore the potential benefits and scientific evidence. ・Quality Control Issues and Tips for Product Selection The market is flooded with NMN supplements. We explain important points consumers need to know—such as purity and manufacturing methods—to distinguish safe, high-quality products. *This audio and description were summarized and created by generative AI based on the original webinar content. The content is for academic and informational purposes only. It is not intended to recommend the purchase of specific products, nor is it intended for the diagnosis, treatment, or prevention of any disease. Please consult a physician or qualified specialist when making any health-related decisions. https://www.youtube-nocookie.com/embed/FQRVsWPuWz0 754 2025-11-13T04:54:22.000Z 2026-10-22T19:04:43.018Z https://longevityharbor.com/en/watch/FV1xThnAU7U Rapamycin, mTOR, and Autophagy Explained | The Longevity Mechanism Most People Miss https://i.ytimg.com/vi/FV1xThnAU7U/hqdefault.jpg Years of research on rapamycin have uncovered a powerful insight about aging that many people still overlook. It turns out that when we eat may matter just as much as what we eat. At the center of this discovery are two critical cellular systems that control growth and repair: mTOR and autophagy. mTOR is activated when nutrients are available. It tells cells to grow, build proteins, repair tissue, and increase metabolic activity. This process is essential for strength, recovery, and survival. However, when mTOR stays active all the time, cells remain in constant growth mode and long term stress begins to build inside the body. Autophagy acts as the counterbalance. It turns on when nutrients are low and allows cells to break down old or damaged components. This internal cleanup process supports detoxification, renewal, and long-term cellular health. Without enough autophagy, damaged material accumulates inside cells, accelerating aging and dysfunction. For most of human history, these two systems were naturally balanced. Food was not always available, so periods of growth were followed by periods of repair. Modern eating patterns have disrupted this rhythm. Frequent meals, constant snacking, and late-night eating keep mTOR activated while autophagy rarely gets enough time to function properly. This imbalance may help explain the rise of chronic disease. Inflammation, metabolic dysfunction, and accelerated aging all share links to impaired cellular cleanup. Rapamycin works by gently reducing mTOR activity, allowing autophagy to restore balance at the cellular level. Understanding this mechanism reframes how we think about longevity. It is not just about adding years, but about giving the body the time it needs to repair, renew, and function better as we age. If this helped you, like, comment, share, and subscribe for more science-based insights on longevity, aging, and human performance. You can see the full video at the link below: https://www.youtube.com/watch?v=wIg8AT152WQ If you are interested in Rapamyc https://www.youtube-nocookie.com/embed/FV1xThnAU7U 237 2025-10-29T21:00:06.000Z 2026-10-22T19:32:35.394Z https://longevityharbor.com/de/watch/FV1xThnAU7U Rapamycin, mTOR, and Autophagy Explained | The Longevity Mechanism Most People Miss https://i.ytimg.com/vi/FV1xThnAU7U/hqdefault.jpg Years of research on rapamycin have uncovered a powerful insight about aging that many people still overlook. It turns out that when we eat may matter just as much as what we eat. At the center of this discovery are two critical cellular systems that control growth and repair: mTOR and autophagy. mTOR is activated when nutrients are available. It tells cells to grow, build proteins, repair tissue, and increase metabolic activity. This process is essential for strength, recovery, and survival. However, when mTOR stays active all the time, cells remain in constant growth mode and long term stress begins to build inside the body. Autophagy acts as the counterbalance. It turns on when nutrients are low and allows cells to break down old or damaged components. This internal cleanup process supports detoxification, renewal, and long-term cellular health. Without enough autophagy, damaged material accumulates inside cells, accelerating aging and dysfunction. For most of human history, these two systems were naturally balanced. Food was not always available, so periods of growth were followed by periods of repair. Modern eating patterns have disrupted this rhythm. Frequent meals, constant snacking, and late-night eating keep mTOR activated while autophagy rarely gets enough time to function properly. This imbalance may help explain the rise of chronic disease. Inflammation, metabolic dysfunction, and accelerated aging all share links to impaired cellular cleanup. Rapamycin works by gently reducing mTOR activity, allowing autophagy to restore balance at the cellular level. Understanding this mechanism reframes how we think about longevity. It is not just about adding years, but about giving the body the time it needs to repair, renew, and function better as we age. If this helped you, like, comment, share, and subscribe for more science-based insights on longevity, aging, and human performance. You can see the full video at the link below: https://www.youtube.com/watch?v=wIg8AT152WQ If you are interested in Rapamyc https://www.youtube-nocookie.com/embed/FV1xThnAU7U 237 2025-10-29T21:00:06.000Z 2026-10-22T19:32:35.394Z https://longevityharbor.com/en/watch/FWMHyS3iU70 Inhibiting mTOR with Rapamycin for Extending Lifespan and Healthspan https://i.ytimg.com/vi/FWMHyS3iU70/hqdefault.jpg Rapamycin appears to be a universal anti-aging drug, extending the lifespan of all animals tested to date; it’s the only known drug to do so. This is the second video in a three-part series. If you missed the first one, check out The Enzyme mTOR as an Engine of Aging (https://nutritionfacts.org/video/the-enzyme-mtor-as-an-engine-of-aging), and stay tuned for Is Rapamycin a Universal Anti-Aging Drug? (https://nutritionfacts.org/video/is-rapamycin-a-universal-anti-aging-drug). For more on longevity, see: • Is Longevity Genetic? (https://nutritionfacts.org/video/is-longevity-genetic/) • Dietary Sources of the “Longevity Vitamin” Ergothioneine (https://nutritionfacts.org/video/dietary-sources-of-the-longevity-vitamin-ergothioneine/) • APOE—The Single Most Important Gene for Longevity (https://nutritionfacts.org/video/apoe-the-single-most-important-gene-for-longevity/) For more on aging, visit your local public library or book seller and check out my longevity book, How Not to Age (https://nutritionfacts.org/book/how-not-to-age/), available in print, e-book, and audio. (All proceeds I receive from the book are donated directly to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/inhibiting-mtor-with-rapamycin-for-extending-lifespan-and-healthspan and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/inhibiting-mtor-with-rapamycin-for-extending-lifespan-and-healthspan. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACL https://www.youtube-nocookie.com/embed/FWMHyS3iU70 262 2024-11-20T12:59:53.000Z 2026-10-22T17:43:41.041Z https://longevityharbor.com/de/watch/FWMHyS3iU70 Inhibiting mTOR with Rapamycin for Extending Lifespan and Healthspan https://i.ytimg.com/vi/FWMHyS3iU70/hqdefault.jpg Rapamycin appears to be a universal anti-aging drug, extending the lifespan of all animals tested to date; it’s the only known drug to do so. This is the second video in a three-part series. If you missed the first one, check out The Enzyme mTOR as an Engine of Aging (https://nutritionfacts.org/video/the-enzyme-mtor-as-an-engine-of-aging), and stay tuned for Is Rapamycin a Universal Anti-Aging Drug? (https://nutritionfacts.org/video/is-rapamycin-a-universal-anti-aging-drug). For more on longevity, see: • Is Longevity Genetic? (https://nutritionfacts.org/video/is-longevity-genetic/) • Dietary Sources of the “Longevity Vitamin” Ergothioneine (https://nutritionfacts.org/video/dietary-sources-of-the-longevity-vitamin-ergothioneine/) • APOE—The Single Most Important Gene for Longevity (https://nutritionfacts.org/video/apoe-the-single-most-important-gene-for-longevity/) For more on aging, visit your local public library or book seller and check out my longevity book, How Not to Age (https://nutritionfacts.org/book/how-not-to-age/), available in print, e-book, and audio. (All proceeds I receive from the book are donated directly to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/inhibiting-mtor-with-rapamycin-for-extending-lifespan-and-healthspan and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/inhibiting-mtor-with-rapamycin-for-extending-lifespan-and-healthspan. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACL https://www.youtube-nocookie.com/embed/FWMHyS3iU70 262 2024-11-20T12:59:53.000Z 2026-10-22T17:43:41.041Z https://longevityharbor.com/en/watch/FWZtb423xQo Rapamycin as a Universal Anti-Aging Drug https://i.ytimg.com/vi/FWZtb423xQo/hqdefault.jpg The side effects of rapamycin. Self-experimentation with the anti-aging drug continues to be strongly discouraged. This is the third and final video in this series. If you missed the previous ones, check out The Enzyme mTOR as an Engine of Aging (https://nutritionfacts.org/video/the-enzyme-mtor-as-an-engine-of-aging) and Inhibiting mTOR with Rapamycin for Extending Lifespan and Healthspan (https://nutritionfacts.org/video/inhibiting-mtor-with-rapamycin-for-extending-lifespan-and-healthspan). So, how do you suppress mTOR without taking drugs? I have a whole chapter on it in How Not to Age (https://nutritionfacts.org/book/how-not-to-age/). (All proceeds I receive from the book are donated directly to charity.) For a teaser, check out these past videos that touch on it: Prevent Cancer from Going on TOR (https://nutritionfacts.org/video/prevent-cancer-from-going-on-tor/) and Caloric Restriction vs. Animal-Protein Restriction (https://nutritionfacts.org/video/caloric-restriction-vs-animal-protein-restriction/). New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/is-rapamycin-a-universal-anti-aging-drug and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/is-rapamycin-a-universal-anti-aging-drug. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Captions for this video are available in several languages; you can find yours in the video settings. View important information about our translated resources: https://nutritionfacts. https://www.youtube-nocookie.com/embed/FWZtb423xQo 271 2024-11-25T12:59:47.000Z 2026-10-22T17:43:41.060Z https://longevityharbor.com/de/watch/FWZtb423xQo Rapamycin as a Universal Anti-Aging Drug https://i.ytimg.com/vi/FWZtb423xQo/hqdefault.jpg The side effects of rapamycin. Self-experimentation with the anti-aging drug continues to be strongly discouraged. This is the third and final video in this series. If you missed the previous ones, check out The Enzyme mTOR as an Engine of Aging (https://nutritionfacts.org/video/the-enzyme-mtor-as-an-engine-of-aging) and Inhibiting mTOR with Rapamycin for Extending Lifespan and Healthspan (https://nutritionfacts.org/video/inhibiting-mtor-with-rapamycin-for-extending-lifespan-and-healthspan). So, how do you suppress mTOR without taking drugs? I have a whole chapter on it in How Not to Age (https://nutritionfacts.org/book/how-not-to-age/). (All proceeds I receive from the book are donated directly to charity.) For a teaser, check out these past videos that touch on it: Prevent Cancer from Going on TOR (https://nutritionfacts.org/video/prevent-cancer-from-going-on-tor/) and Caloric Restriction vs. Animal-Protein Restriction (https://nutritionfacts.org/video/caloric-restriction-vs-animal-protein-restriction/). New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/is-rapamycin-a-universal-anti-aging-drug and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/is-rapamycin-a-universal-anti-aging-drug. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Captions for this video are available in several languages; you can find yours in the video settings. View important information about our translated resources: https://nutritionfacts. https://www.youtube-nocookie.com/embed/FWZtb423xQo 271 2024-11-25T12:59:47.000Z 2026-10-22T17:43:41.060Z https://longevityharbor.com/en/watch/FXbanqer1fQ Stanford Grand Rounds talk on fasting-mimicking diet cycles and multi-system reprogramming https://i.ytimg.com/vi/FXbanqer1fQ/hqdefault.jpg According to the description, Valter Longo, MD, professor of gerontology and biological sciences at the University of Southern California, presented a Stanford Department of Medicine Grand Rounds talk on March 11, 2026, titled 'Fasting Mimicking Diet Cycles, Multi System Reprogramming and Disease.' The description credits his fasting-mimicking diet work with shaping approaches to healthy aging and disease prevention. https://www.youtube-nocookie.com/embed/FXbanqer1fQ 2620 2026-03-24T23:17:41.000Z 2026-10-23T01:52:36.865Z https://longevityharbor.com/de/watch/FXbanqer1fQ Stanford-Grand-Rounds-Vortrag über Zyklen der fastenimitierenden Diät und Multisystem-Reprogrammieru https://i.ytimg.com/vi/FXbanqer1fQ/hqdefault.jpg Laut Beschreibung hielt Valter Longo, MD, Professor für Gerontologie und Biowissenschaften an der University of Southern California, am 11. März 2026 eine Grand-Rounds-Veranstaltung der Stanford Department of Medicine mit dem Titel „Fasting Mimicking Diet Cycles, Multi System Reprogramming and Disease“. Die Beschreibung schreibt seiner Arbeit zur fastenimitierenden Diät prägenden Einfluss auf Ansätze für gesundes Altern und Krankheitsvorbeugung zu. https://www.youtube-nocookie.com/embed/FXbanqer1fQ 2620 2026-03-24T23:17:41.000Z 2026-10-23T01:52:36.865Z https://longevityharbor.com/en/watch/F_KZrNhWURQ Fasting Mimicking Diet- AGE REVERSAL of 2.5 YEARS in new study! + Fasting’s effect on Alzheimer’s https://i.ytimg.com/vi/F_KZrNhWURQ/hqdefault.jpg In this video nutrition and Longevity Pro Joe Condora discusses a brand new study involving Valter Longo, a proponent of the Fasting Mimicking Diet. The study looks at the effects of a Fasting Mimicking Diets and intermittent fasting on biological age, liver fat, insulin resistance, and abdominal fat. We also explore other studies examining the effects of fasting on Alzheimer’s and cortisol levels. Follow Joe on Instagram: https://www.instagram.com/joecondora/ https://www.youtube-nocookie.com/embed/F_KZrNhWURQ 1040 2024-02-22T20:17:32.000Z 2026-10-22T19:54:18.223Z https://longevityharbor.com/de/watch/F_KZrNhWURQ Fasting Mimicking Diet- AGE REVERSAL of 2.5 YEARS in new study! + Fasting’s effect on Alzheimer’s https://i.ytimg.com/vi/F_KZrNhWURQ/hqdefault.jpg In this video nutrition and Longevity Pro Joe Condora discusses a brand new study involving Valter Longo, a proponent of the Fasting Mimicking Diet. The study looks at the effects of a Fasting Mimicking Diets and intermittent fasting on biological age, liver fat, insulin resistance, and abdominal fat. We also explore other studies examining the effects of fasting on Alzheimer’s and cortisol levels. Follow Joe on Instagram: https://www.instagram.com/joecondora/ https://www.youtube-nocookie.com/embed/F_KZrNhWURQ 1040 2024-02-22T20:17:32.000Z 2026-10-22T19:54:18.223Z https://longevityharbor.com/en/watch/Fm6-OhdeyuU Lifting Weights Protects Your Brain in 3 Ways https://i.ytimg.com/vi/Fm6-OhdeyuU/hqdefault.jpg Lifting weights protects your brain in three ways, and none of them are about muscle size. Strength training raises IGF-1, a growth factor in your blood that can reach the brain and help nerve cells survive and adapt. It also lowers markers of chronic inflammation. And in a randomized trial of older adults, heavy resistance training increased connectivity in the front of the brain, meaning those regions worked together more closely. Newer animal research suggests muscle can send signals to the brain through the bloodstream. So when you train, think beyond muscle size. Your muscles are part of the system that supports your brain. If this was helpful, subscribe for more on keeping your brain sharp, and share it with someone who's been meaning to start lifting. Comment below: how many days a week do you lift? optimizecognition.com Sources 1. Rodríguez-Gutiérrez E, et al. Effects of Resistance Exercise on Neuroprotective Factors in Middle and Late Life: A Systematic Review and Meta-Analysis. Aging and Disease, 2023. https://doi.org/10.14336/AD.2022.1207 2. Liu et al. Restoring the balance: Resistance exercise-induced insulin-like growth factor-1 restores PI3K/Akt and MAPK/ERK cross-talk to ameliorate Alzheimer's disease. Ageing Research Reviews, 2026. https://doi.org/10.1016/j.arr.2026.103239 3. Qipo O, et al. Dose-response relationship of resistance training and the effects on circulating biomarkers of inflammation or neuroplasticity in older adults: A systematic review and meta-analysis. Ageing Research Reviews, 2026. https://doi.org/10.1016/j.arr.2025.102917 4. Gonzalez-Gomez R, et al. Randomized controlled trial of resistance exercise and brain aging clocks. GeroScience, 2026. https://doi.org/10.1007/s11357-026-02141-x 5. Lin H, et al. Muscle-Derived Small Extracellular Vesicles Mediate Exercise-Induced Cognitive Protection in Chronic Cerebral Hypoperfusion. Advanced Science, 2025. https://doi.org/10.1002/advs.202410209 The brain scans in this video are a standard MRI template. The highlighted prefrontal r https://www.youtube-nocookie.com/embed/Fm6-OhdeyuU 132 2026-10-21T21:50:17.000Z 2026-10-22T19:54:15.810Z https://longevityharbor.com/de/watch/Fm6-OhdeyuU Lifting Weights Protects Your Brain in 3 Ways https://i.ytimg.com/vi/Fm6-OhdeyuU/hqdefault.jpg Lifting weights protects your brain in three ways, and none of them are about muscle size. Strength training raises IGF-1, a growth factor in your blood that can reach the brain and help nerve cells survive and adapt. It also lowers markers of chronic inflammation. And in a randomized trial of older adults, heavy resistance training increased connectivity in the front of the brain, meaning those regions worked together more closely. Newer animal research suggests muscle can send signals to the brain through the bloodstream. So when you train, think beyond muscle size. Your muscles are part of the system that supports your brain. If this was helpful, subscribe for more on keeping your brain sharp, and share it with someone who's been meaning to start lifting. Comment below: how many days a week do you lift? optimizecognition.com Sources 1. Rodríguez-Gutiérrez E, et al. Effects of Resistance Exercise on Neuroprotective Factors in Middle and Late Life: A Systematic Review and Meta-Analysis. Aging and Disease, 2023. https://doi.org/10.14336/AD.2022.1207 2. Liu et al. Restoring the balance: Resistance exercise-induced insulin-like growth factor-1 restores PI3K/Akt and MAPK/ERK cross-talk to ameliorate Alzheimer's disease. Ageing Research Reviews, 2026. https://doi.org/10.1016/j.arr.2026.103239 3. Qipo O, et al. Dose-response relationship of resistance training and the effects on circulating biomarkers of inflammation or neuroplasticity in older adults: A systematic review and meta-analysis. Ageing Research Reviews, 2026. https://doi.org/10.1016/j.arr.2025.102917 4. Gonzalez-Gomez R, et al. Randomized controlled trial of resistance exercise and brain aging clocks. GeroScience, 2026. https://doi.org/10.1007/s11357-026-02141-x 5. Lin H, et al. Muscle-Derived Small Extracellular Vesicles Mediate Exercise-Induced Cognitive Protection in Chronic Cerebral Hypoperfusion. Advanced Science, 2025. https://doi.org/10.1002/advs.202410209 The brain scans in this video are a standard MRI template. The highlighted prefrontal r https://www.youtube-nocookie.com/embed/Fm6-OhdeyuU 132 2026-10-21T21:50:17.000Z 2026-10-22T19:54:15.810Z https://longevityharbor.com/en/watch/FmODaUB7HMU The Secrets of Epigenetic Aging | How to Slow Down Your Biological Clock https://i.ytimg.com/vi/FmODaUB7HMU/hqdefault.jpg The Secrets of Epigenetic Aging: A Quick Breakdown 🧬 1. It’s Not Just Your DNA That Ages Your DNA stays the same, but epigenetic markers, like DNA methylation—change with age. These chemical "tags" turn genes on or off, affecting how your body functions as you grow older. ⏳ 2. Epigenetic Clocks Predict Biological Age Scientists like Dr. Steve Horvath developed epigenetic clocks that can estimate your "biological age" based on DNA methylation patterns. This may be more accurate than your actual age in predicting health, disease, or lifespan. 🍎 3. Lifestyle Directly Affects Epigenetic Aging Diet, exercise, sleep, and stress all impact gene expression. For example: Poor sleep or chronic stress can accelerate aging. A plant-rich diet, regular exercise, and mindfulness can reverse or slow epigenetic aging. 🧪 4. Reversal Might Be Possible Some studies show epigenetic age can be reversed. In a 2019 clinical trial, participants reduced their biological age by 2.5 years through diet, supplements, exercise, and sleep optimisation—all within 8 weeks. 🧠 5. Mind Over Methylation Stress and trauma can leave a lasting "epigenetic scar" on your genes. On the flip side, meditation, positive relationships, and emotional regulation can support healthy gene expression and longevity. 🧊 6. Cold, Fasting & Hormesis Play a Role Practices like intermittent fasting, cold exposure, and mild stressors (known as hormesis) can activate protective genes and boost resilience—possibly slowing aging at the epigenetic level. 🧬 7. Targeted Therapies Are Emerging Companies and labs are working on drugs and gene therapies that target epigenetic changes to slow aging, treat age-related diseases, or even reprogram cells to a younger state. epigenetic aging, anti-aging, epigenetic, reverse aging, biological age, DNA methylation, how to live longer, longevity tips, anti-aging secrets, biohacking, healthy aging, epigenetic clock, Steve Horvath, slow down aging, lifestyle and aging, gene expression, anti-aging diet, longevity hacks, aging science, https://www.youtube-nocookie.com/embed/FmODaUB7HMU 163 2025-03-21T10:10:19.000Z 2026-10-22T19:21:27.600Z https://longevityharbor.com/de/watch/FmODaUB7HMU The Secrets of Epigenetic Aging | How to Slow Down Your Biological Clock https://i.ytimg.com/vi/FmODaUB7HMU/hqdefault.jpg The Secrets of Epigenetic Aging: A Quick Breakdown 🧬 1. It’s Not Just Your DNA That Ages Your DNA stays the same, but epigenetic markers, like DNA methylation—change with age. These chemical "tags" turn genes on or off, affecting how your body functions as you grow older. ⏳ 2. Epigenetic Clocks Predict Biological Age Scientists like Dr. Steve Horvath developed epigenetic clocks that can estimate your "biological age" based on DNA methylation patterns. This may be more accurate than your actual age in predicting health, disease, or lifespan. 🍎 3. Lifestyle Directly Affects Epigenetic Aging Diet, exercise, sleep, and stress all impact gene expression. For example: Poor sleep or chronic stress can accelerate aging. A plant-rich diet, regular exercise, and mindfulness can reverse or slow epigenetic aging. 🧪 4. Reversal Might Be Possible Some studies show epigenetic age can be reversed. In a 2019 clinical trial, participants reduced their biological age by 2.5 years through diet, supplements, exercise, and sleep optimisation—all within 8 weeks. 🧠 5. Mind Over Methylation Stress and trauma can leave a lasting "epigenetic scar" on your genes. On the flip side, meditation, positive relationships, and emotional regulation can support healthy gene expression and longevity. 🧊 6. Cold, Fasting & Hormesis Play a Role Practices like intermittent fasting, cold exposure, and mild stressors (known as hormesis) can activate protective genes and boost resilience—possibly slowing aging at the epigenetic level. 🧬 7. Targeted Therapies Are Emerging Companies and labs are working on drugs and gene therapies that target epigenetic changes to slow aging, treat age-related diseases, or even reprogram cells to a younger state. epigenetic aging, anti-aging, epigenetic, reverse aging, biological age, DNA methylation, how to live longer, longevity tips, anti-aging secrets, biohacking, healthy aging, epigenetic clock, Steve Horvath, slow down aging, lifestyle and aging, gene expression, anti-aging diet, longevity hacks, aging science, https://www.youtube-nocookie.com/embed/FmODaUB7HMU 163 2025-03-21T10:10:19.000Z 2026-10-22T19:21:27.600Z https://longevityharbor.com/en/watch/Fq3Ix30FhkA Calorie Restriction Live Longer https://i.ytimg.com/vi/Fq3Ix30FhkA/hqdefault.jpg an eating less really make you live longer? 🤯 Scientific studies suggest that calorie restriction can slow aging and reduce the risk of serious diseases. In this video, you’ll discover what’s really behind this idea — and why most people misunderstand it. https://www.youtube-nocookie.com/embed/Fq3Ix30FhkA 145 2025-11-23T15:54:15.000Z 2026-10-22T18:54:07.974Z https://longevityharbor.com/de/watch/Fq3Ix30FhkA Calorie Restriction Live Longer https://i.ytimg.com/vi/Fq3Ix30FhkA/hqdefault.jpg an eating less really make you live longer? 🤯 Scientific studies suggest that calorie restriction can slow aging and reduce the risk of serious diseases. In this video, you’ll discover what’s really behind this idea — and why most people misunderstand it. https://www.youtube-nocookie.com/embed/Fq3Ix30FhkA 145 2025-11-23T15:54:15.000Z 2026-10-22T18:54:07.974Z https://longevityharbor.com/en/watch/Fq70vOkb0mo Building Muscle in your 80s & 90s: What Research Reveals About Aging & Function - w/ Prof Fiatarone https://i.ytimg.com/vi/Fq70vOkb0mo/hqdefault.jpg 🎓 Enrol in the 9-Week Science of Thriving Course → https://scienceofthriving.com.au 📲 Follow us on Instagram → @tonyboutagy 🎧 Listen on all platforms → https://open.spotify.com/show/5Yydg6y3dA8OiA8hyHcJON In this episode, I sit down with Professor Maria Fiatarone Singh - the pioneering geriatrician whose groundbreaking 1980s research proved that frail individuals in their 80s and 90s could not only lift weights safely, but actually grow bigger, stronger muscles. Her four decades of research have reshaped exercise prescription for aging and chronic disease, showing that high-intensity resistance training is the single most powerful intervention for maintaining independence, preventing falls, and treating conditions like osteoporosis, cognitive decline, and type 2 diabetes. Her research has produced outcomes few thought possible - like an 85% reduction in death rates after hip fracture. 🎙️ Episode Highlights: 00:00 – How watching Jack LaLanne with her grandmother led to a career in geriatric medicine 03:00 – The 1988 pilot study that shocked the medical world: frail 90-year-olds gaining 200% strength 06:00 – Why Maria started with 80% intensity from day four (when others took months) 09:00 – The detraining study: losing a third of gains in just four weeks without exercise 11:00 – The FIXIT study: using SMILE exercise as the perfect placebo control 13:00 – Muscle biopsy findings: new muscle fiber formation in frail elderly 17:00 – Why resistance training is nitrogen-retentive (the opposite of what everyone thinks) 19:00 – The functional training myth: how simple leg press improved all daily activities 23:00 – Getting 10% VO2 max improvements from weightlifting alone 27:00 – Why resistance training is more feasible than aerobic exercise in frail populations 29:00 – The woman with one working muscle: why everyone needs resistance training 35:00 – Hip fracture recovery: 13 interventions that reduced death rates by 85% 40:00 – Bone loading prescription: why 80% intensity beats complicated protocols 48:00 – B https://www.youtube-nocookie.com/embed/Fq70vOkb0mo 3955 2025-08-04T20:00:19.000Z 2026-10-22T18:32:08.320Z https://longevityharbor.com/de/watch/Fq70vOkb0mo Building Muscle in your 80s & 90s: What Research Reveals About Aging & Function - w/ Prof Fiatarone https://i.ytimg.com/vi/Fq70vOkb0mo/hqdefault.jpg 🎓 Enrol in the 9-Week Science of Thriving Course → https://scienceofthriving.com.au 📲 Follow us on Instagram → @tonyboutagy 🎧 Listen on all platforms → https://open.spotify.com/show/5Yydg6y3dA8OiA8hyHcJON In this episode, I sit down with Professor Maria Fiatarone Singh - the pioneering geriatrician whose groundbreaking 1980s research proved that frail individuals in their 80s and 90s could not only lift weights safely, but actually grow bigger, stronger muscles. Her four decades of research have reshaped exercise prescription for aging and chronic disease, showing that high-intensity resistance training is the single most powerful intervention for maintaining independence, preventing falls, and treating conditions like osteoporosis, cognitive decline, and type 2 diabetes. Her research has produced outcomes few thought possible - like an 85% reduction in death rates after hip fracture. 🎙️ Episode Highlights: 00:00 – How watching Jack LaLanne with her grandmother led to a career in geriatric medicine 03:00 – The 1988 pilot study that shocked the medical world: frail 90-year-olds gaining 200% strength 06:00 – Why Maria started with 80% intensity from day four (when others took months) 09:00 – The detraining study: losing a third of gains in just four weeks without exercise 11:00 – The FIXIT study: using SMILE exercise as the perfect placebo control 13:00 – Muscle biopsy findings: new muscle fiber formation in frail elderly 17:00 – Why resistance training is nitrogen-retentive (the opposite of what everyone thinks) 19:00 – The functional training myth: how simple leg press improved all daily activities 23:00 – Getting 10% VO2 max improvements from weightlifting alone 27:00 – Why resistance training is more feasible than aerobic exercise in frail populations 29:00 – The woman with one working muscle: why everyone needs resistance training 35:00 – Hip fracture recovery: 13 interventions that reduced death rates by 85% 40:00 – Bone loading prescription: why 80% intensity beats complicated protocols 48:00 – B https://www.youtube-nocookie.com/embed/Fq70vOkb0mo 3955 2025-08-04T20:00:19.000Z 2026-10-22T18:32:08.320Z https://longevityharbor.com/en/watch/Frn2ixdkcJ4 Anti-Aging ist ein Mythos: Was dich wirklich länger jung hält. Mit Prof. Dr. Volker Steinkraus. #222 https://i.ytimg.com/vi/Frn2ixdkcJ4/hqdefault.jpg Warum manche Menschen 10 Jahre jünger aussehen – und was wirklich dahintersteckt!** 🧬✨ „Anti-Aging ist wie Anti-Sonnenuntergang.“ - Mit dieser Aussage stellt Prof. Dr. Volker Steinkraus einen der größten Beauty-Trends unserer Zeit infrage. Was wäre, wenn wir uns weniger darauf konzentrieren würden, das Altern aufzuhalten, und stattdessen lernen, besser zu altern? In dieser besonderen Live-Episode von HEALTHWISE, aufgenommen im Sommerzuhause von Mercedes-Benz auf Sylt, spricht Nils Behrens mit dem renommierten Dermatologen Prof. Dr. Volker Steinkraus über die zehn Prinzipien aus seinem Buch "How to Look Better". Und die haben es in sich! Denn neben Hautpflege, Ernährung und Sonnenschutz geht es um Dinge, die du vermutlich nicht auf deiner Beauty-Checkliste stehen hast: Freundschaften mit Menschen unterschiedlicher Generationen, körperliche Nähe, Toleranz und die Fähigkeit, das Leben mit mehr Leichtigkeit zu genießen. 💡 Was dich in dieser Folge erwartet: 🧬 Anti-Aging oder Slow Aging? Warum wir das Älterwerden nicht verhindern können und was es bedeutet, möglichst lange gesund und selbstständig zu bleiben. 💤 Gibt es den Schönheitsschlaf wirklich? Wie sich Schlafmangel auf unsere Haut auswirkt und welche Gewohnheiten deinen Schlaf unterstützen können. 🥗 Schönheit von innen: Warum eine ausgewogene Ernährung nicht nur für die Haut, sondern für den gesamten Körper wichtig ist. 🏃 Bewegung statt Beauty-Wundermittel: Weshalb der Dermatologe regelmäßige Bewegung für seine wichtigste Empfehlung hält. 🚭 Rauchen und Hautalterung: Wie Rauchen Kollagen und Wundheilung beeinflusst und welche Schäden langfristig entstehen können. ☀️ Sonne: Freund oder Feind? Warum es auf deinen Hauttyp ankommt, welche Rolle UV-Strahlung spielt und welchen Fehler viele beim Eincremen machen. 🧴 Welche Hautpflege wirkt wirklich? Was Vitamin A, Vitamin C, Niacinamid und Fruchtsäuren leisten können - und warum Prof. Dr. Steinkraus den Hype um manche Wirkstoffe kritisch betrachtet. 🤝 Warum Freundschaften jung halten können: Was Bez https://www.youtube-nocookie.com/embed/Frn2ixdkcJ4 3429 2026-10-15T15:00:39.000Z 2026-10-22T20:11:49.315Z https://longevityharbor.com/de/watch/Frn2ixdkcJ4 Anti-Aging ist ein Mythos: Was dich wirklich länger jung hält. Mit Prof. Dr. Volker Steinkraus. #222 https://i.ytimg.com/vi/Frn2ixdkcJ4/hqdefault.jpg Warum manche Menschen 10 Jahre jünger aussehen – und was wirklich dahintersteckt!** 🧬✨ „Anti-Aging ist wie Anti-Sonnenuntergang.“ - Mit dieser Aussage stellt Prof. Dr. Volker Steinkraus einen der größten Beauty-Trends unserer Zeit infrage. Was wäre, wenn wir uns weniger darauf konzentrieren würden, das Altern aufzuhalten, und stattdessen lernen, besser zu altern? In dieser besonderen Live-Episode von HEALTHWISE, aufgenommen im Sommerzuhause von Mercedes-Benz auf Sylt, spricht Nils Behrens mit dem renommierten Dermatologen Prof. Dr. Volker Steinkraus über die zehn Prinzipien aus seinem Buch "How to Look Better". Und die haben es in sich! Denn neben Hautpflege, Ernährung und Sonnenschutz geht es um Dinge, die du vermutlich nicht auf deiner Beauty-Checkliste stehen hast: Freundschaften mit Menschen unterschiedlicher Generationen, körperliche Nähe, Toleranz und die Fähigkeit, das Leben mit mehr Leichtigkeit zu genießen. 💡 Was dich in dieser Folge erwartet: 🧬 Anti-Aging oder Slow Aging? Warum wir das Älterwerden nicht verhindern können und was es bedeutet, möglichst lange gesund und selbstständig zu bleiben. 💤 Gibt es den Schönheitsschlaf wirklich? Wie sich Schlafmangel auf unsere Haut auswirkt und welche Gewohnheiten deinen Schlaf unterstützen können. 🥗 Schönheit von innen: Warum eine ausgewogene Ernährung nicht nur für die Haut, sondern für den gesamten Körper wichtig ist. 🏃 Bewegung statt Beauty-Wundermittel: Weshalb der Dermatologe regelmäßige Bewegung für seine wichtigste Empfehlung hält. 🚭 Rauchen und Hautalterung: Wie Rauchen Kollagen und Wundheilung beeinflusst und welche Schäden langfristig entstehen können. ☀️ Sonne: Freund oder Feind? Warum es auf deinen Hauttyp ankommt, welche Rolle UV-Strahlung spielt und welchen Fehler viele beim Eincremen machen. 🧴 Welche Hautpflege wirkt wirklich? Was Vitamin A, Vitamin C, Niacinamid und Fruchtsäuren leisten können - und warum Prof. Dr. Steinkraus den Hype um manche Wirkstoffe kritisch betrachtet. 🤝 Warum Freundschaften jung halten können: Was Bez https://www.youtube-nocookie.com/embed/Frn2ixdkcJ4 3429 2026-10-15T15:00:39.000Z 2026-10-22T20:11:49.315Z https://longevityharbor.com/en/watch/FsuhrvnQgp8 Spermidine: The Molecule Behind Fasting's Anti Aging Magic https://i.ytimg.com/vi/FsuhrvnQgp8/hqdefault.jpg The link to the original paper: https://www.nature.com/articles/s41556-024-01468-x Key-words: Anti-arthritic effects, Autophagy, Caloric restriction, Cardioprotection, Deoxyhypusine hydroxylase, Deoxyhypusine synthase, DFMO, eIF5A, eIF5A hypusination, Fasting, Flies, Geroprotection, Healthspan, Humans, Inflammation, Intermittent fasting, Longevity, Metabolic control hub, Mice, Ornithine decarboxylase, Polyamines, Spermidine, TORC1 inhibition, Worms, Yeast https://www.youtube-nocookie.com/embed/FsuhrvnQgp8 375 2025-08-02T05:10:18.000Z 2026-10-22T19:54:18.200Z https://longevityharbor.com/de/watch/FsuhrvnQgp8 Spermidine: The Molecule Behind Fasting's Anti Aging Magic https://i.ytimg.com/vi/FsuhrvnQgp8/hqdefault.jpg The link to the original paper: https://www.nature.com/articles/s41556-024-01468-x Key-words: Anti-arthritic effects, Autophagy, Caloric restriction, Cardioprotection, Deoxyhypusine hydroxylase, Deoxyhypusine synthase, DFMO, eIF5A, eIF5A hypusination, Fasting, Flies, Geroprotection, Healthspan, Humans, Inflammation, Intermittent fasting, Longevity, Metabolic control hub, Mice, Ornithine decarboxylase, Polyamines, Spermidine, TORC1 inhibition, Worms, Yeast https://www.youtube-nocookie.com/embed/FsuhrvnQgp8 375 2025-08-02T05:10:18.000Z 2026-10-22T19:54:18.200Z https://longevityharbor.com/en/watch/FtDmz8Vv2F8 Underlying Features of Epigenetic Aging Clocks | Morgan Levine, Yale University https://i.ytimg.com/vi/FtDmz8Vv2F8/hqdefault.jpg Foresight Biotech & Health Extension 2021 program & apply to join: https://foresight.org/biotech-health-extension-program/ Morgan Levine, Yale University | Underlying Features of Epigenetic Aging Clocks We will be joined by Morgan Levine, Yale University, to discuss the recent article "Underlying Features of Epigenetic Aging Clocks" she co-authored. The talk will compare and contrast existing epigenetic clocks and describe how they can be deconstructed to facilitate our understanding of causes and consequences of epigenetic aging. Article Abstract: Epigenetic clocks, developed using DNA methylation data, have been widely used to quantify biological aging in multiple tissues/cells. However, many existing epigenetic clocks are weakly correlated with each other, suggesting they may capture different biological processes. We utilize multi‐omics data from diverse human tissue/cells to identify shared features across eleven existing epigenetic clocks. Despite the striking lack of overlap in CpGs, multi‐omics analysis suggested five clocks (Horvath1, Horvath2, Levine, Hannum, and Lin) share transcriptional associations conserved across purified CD14+ monocytes and dorsolateral prefrontal cortex. The pathways enriched in the shared transcriptional association suggested links between epigenetic aging and metabolism, immunity, and autophagy. Results from in vitro experiments showed that two clocks (Levine and Lin) were accelerated in accordance with two hallmarks of aging—cellular senescence and mitochondrial dysfunction. Finally, using multi‐tissue data to deconstruct the epigenetic clock signals, we developed a meta‐clock that demonstrated improved prediction for mortality and robustly related to hallmarks of aging in vitro than single clocks. Morgan's Bio: Morgan Levine is a ladder-rank Assistant Professor in the Department of Pathology at the Yale School of Medicine and a member of both the Yale Combined Program in Computational Biology and Bioinformatics, and the Yale Center for Research on Aging. Her work reli https://www.youtube-nocookie.com/embed/FtDmz8Vv2F8 3528 2020-11-27T19:37:40.000Z 2026-10-22T17:43:35.213Z https://longevityharbor.com/de/watch/FtDmz8Vv2F8 Underlying Features of Epigenetic Aging Clocks | Morgan Levine, Yale University https://i.ytimg.com/vi/FtDmz8Vv2F8/hqdefault.jpg Foresight Biotech & Health Extension 2021 program & apply to join: https://foresight.org/biotech-health-extension-program/ Morgan Levine, Yale University | Underlying Features of Epigenetic Aging Clocks We will be joined by Morgan Levine, Yale University, to discuss the recent article "Underlying Features of Epigenetic Aging Clocks" she co-authored. The talk will compare and contrast existing epigenetic clocks and describe how they can be deconstructed to facilitate our understanding of causes and consequences of epigenetic aging. Article Abstract: Epigenetic clocks, developed using DNA methylation data, have been widely used to quantify biological aging in multiple tissues/cells. However, many existing epigenetic clocks are weakly correlated with each other, suggesting they may capture different biological processes. We utilize multi‐omics data from diverse human tissue/cells to identify shared features across eleven existing epigenetic clocks. Despite the striking lack of overlap in CpGs, multi‐omics analysis suggested five clocks (Horvath1, Horvath2, Levine, Hannum, and Lin) share transcriptional associations conserved across purified CD14+ monocytes and dorsolateral prefrontal cortex. The pathways enriched in the shared transcriptional association suggested links between epigenetic aging and metabolism, immunity, and autophagy. Results from in vitro experiments showed that two clocks (Levine and Lin) were accelerated in accordance with two hallmarks of aging—cellular senescence and mitochondrial dysfunction. Finally, using multi‐tissue data to deconstruct the epigenetic clock signals, we developed a meta‐clock that demonstrated improved prediction for mortality and robustly related to hallmarks of aging in vitro than single clocks. Morgan's Bio: Morgan Levine is a ladder-rank Assistant Professor in the Department of Pathology at the Yale School of Medicine and a member of both the Yale Combined Program in Computational Biology and Bioinformatics, and the Yale Center for Research on Aging. Her work reli https://www.youtube-nocookie.com/embed/FtDmz8Vv2F8 3528 2020-11-27T19:37:40.000Z 2026-10-22T17:43:35.213Z https://longevityharbor.com/en/watch/Fuei6UzOGhs Nutrition as an immune tool: what this webinar description promises https://i.ytimg.com/vi/Fuei6UzOGhs/hqdefault.jpg A webinar description says clinical nutritionist Marie Ruggles will present food and nutrient strategies intended to support immune resilience and long-term health. No study results, numbers or outcomes are reported in the description. https://www.youtube-nocookie.com/embed/Fuei6UzOGhs 4828 2026-10-22T17:59:57.000Z 2026-10-22T19:45:14.413Z https://longevityharbor.com/de/watch/Fuei6UzOGhs Ernährung als Werkzeug für das Immunsystem: Was die Webinar-Beschreibung ankündigt https://i.ytimg.com/vi/Fuei6UzOGhs/hqdefault.jpg Eine Webinar-Beschreibung kündigt an, dass die klinische Ernährungsberaterin Marie Ruggles Ernährungs- und Nährstoffstrategien vorstellt, die Immunresilienz und langfristige Gesundheit unterstützen sollen. Ergebnisse, Zahlen oder Endpunkte nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/Fuei6UzOGhs 4828 2026-10-22T17:59:57.000Z 2026-10-22T19:45:14.413Z https://longevityharbor.com/en/watch/G-eqHb5F1TE Poletti talk description: autophagy and motor neuron proteotoxicity https://i.ytimg.com/vi/G-eqHb5F1TE/hqdefault.jpg The description says Professor Angelo Poletti's Milan Longevity Summit 2026 session covers how autophagy, a cell quality-control mechanism, may protect motor neurons from proteotoxic stress, and how weaker clearance with age might relate to neurodegenerative disease. https://www.youtube-nocookie.com/embed/G-eqHb5F1TE 1292 2026-08-08T10:45:26.000Z 2026-10-22T23:08:41.867Z https://longevityharbor.com/de/watch/G-eqHb5F1TE Poletti-Vortragsbeschreibung: Autophagie und Proteotoxizität motorischer Neuronen https://i.ytimg.com/vi/G-eqHb5F1TE/hqdefault.jpg Laut Beschreibung behandelt die Sitzung von Professor Angelo Poletti beim Milan Longevity Summit 2026, wie Autophagie als zellulärer Qualitätskontrollmechanismus motorische Neuronen vor proteotoxischem Stress schützen könnte und wie eine mit dem Alter nachlassende Clearance mit neurodegenerativen Erkrankungen zusammenhängen könnte. https://www.youtube-nocookie.com/embed/G-eqHb5F1TE 1292 2026-08-08T10:45:26.000Z 2026-10-22T23:08:41.867Z https://longevityharbor.com/en/watch/G8-oXN2dlxQ Bas Kast on healthy ageing: habits, muscle strength and loneliness https://i.ytimg.com/vi/G8-oXN2dlxQ/hqdefault.jpg In this podcast description, science journalist Bas Kast discusses which habits influence healthy ageing, why longevity means more than a long life, and what research can support. https://www.youtube-nocookie.com/embed/G8-oXN2dlxQ 4028 2026-06-28T10:00:24.000Z 2026-10-22T23:46:33.011Z https://longevityharbor.com/de/watch/G8-oXN2dlxQ Bas Kast über gesundes Altern: Gewohnheiten, Muskelkraft und Einsamkeit https://i.ytimg.com/vi/G8-oXN2dlxQ/hqdefault.jpg In dieser Podcast-Beschreibung spricht Wissenschaftsjournalist Bas Kast darüber, welche Gewohnheiten gesundes Altern beeinflussen, warum Longevity mehr als ein langes Leben bedeutet und was die Forschung belegen kann. https://www.youtube-nocookie.com/embed/G8-oXN2dlxQ 4028 2026-06-28T10:00:24.000Z 2026-10-22T23:46:33.011Z https://longevityharbor.com/en/watch/GBB0qRyot5g Ich habe 1 Jahr NMN genommen und das ist passiert! Meine Nicotinamide Mononucleotide Erfahrungen https://i.ytimg.com/vi/GBB0qRyot5g/hqdefault.jpg Kann man den Alterungsprozess stoppen und die Zellen verjüngen? In diesem Video teile ich, Elisabeth Eberl, meine Erfahrungen mit NMN (Nicotinamide Mononucleotide). Seit 14 Monaten nehme ich NMN ein und verrate dir, was sich dadurch verändert hat – von meiner Morgenroutine über meine Energie bis hin zu meiner Produktivität und meinem Wohlbefinden. David Sinclair schwört auf NMN, und es gibt viele Studien zu den NMN Benefits – darunter das Potenzial, das Altern zu verlangsamen oder sogar zu stoppen. Aber ist NMN sicher? Was sind die Vorteile von Nicotinamide Mononucleotide, und kann es wirklich helfen, mehr Erfolg im Business und eine bessere Balance im Leben zu erreichen? Ich nehme dieses NMN - 40% SPAREN - UTHEVER NMN in Top Qualität, 99,8% - Nutze den folgenden Link und den CODE 'LONGEVITY' um dir bis zu 40% Rabatt zu sichern (*): ➤ https://enduravita.eu/products/nmn-pure-powder/?sca_ref=6527249.kOBQqzVXSV @HOME LONGEVITY TEST: NAD+ Spiegel testen: Nutze den CODE "ELISABETHEBERL" und diesen Link für 15% Rabatt (*): ➤ https://avea-life.com/products/longevity-nad-test?sub_id=ELISABETHEBERL ....................................................................................................................................................... Nicht Altern - Lachssperma wie Kim Kardashian? ➤ https://youtu.be/ASIp9hamiFk Zellalterung stoppen mit NMN: ➤ https://youtu.be/-9J2_Go0Wic Alterung stoppen ohne BOTOX: ➤ https://youtu.be/B8xHzogWD2o Geheimnis ewiger Jugend von Kim Kardashian: ➤ https://youtu.be/9N1Aw1XNDGE Das High Performance Geheimnis von Top CEOS (kein Lachssperma) ➤ https://youtu.be/kASxnOiGiIs ....................................................................................................................................................... Mehr erfahren: https://bio.site/elisabetheberl International inquiries in English available. ....................................................................................................................................................... ➤ Instag https://www.youtube-nocookie.com/embed/GBB0qRyot5g 355 2024-09-26T07:58:32.000Z 2026-10-22T20:11:46.996Z https://longevityharbor.com/de/watch/GBB0qRyot5g Ich habe 1 Jahr NMN genommen und das ist passiert! Meine Nicotinamide Mononucleotide Erfahrungen https://i.ytimg.com/vi/GBB0qRyot5g/hqdefault.jpg Kann man den Alterungsprozess stoppen und die Zellen verjüngen? In diesem Video teile ich, Elisabeth Eberl, meine Erfahrungen mit NMN (Nicotinamide Mononucleotide). Seit 14 Monaten nehme ich NMN ein und verrate dir, was sich dadurch verändert hat – von meiner Morgenroutine über meine Energie bis hin zu meiner Produktivität und meinem Wohlbefinden. David Sinclair schwört auf NMN, und es gibt viele Studien zu den NMN Benefits – darunter das Potenzial, das Altern zu verlangsamen oder sogar zu stoppen. Aber ist NMN sicher? Was sind die Vorteile von Nicotinamide Mononucleotide, und kann es wirklich helfen, mehr Erfolg im Business und eine bessere Balance im Leben zu erreichen? Ich nehme dieses NMN - 40% SPAREN - UTHEVER NMN in Top Qualität, 99,8% - Nutze den folgenden Link und den CODE 'LONGEVITY' um dir bis zu 40% Rabatt zu sichern (*): ➤ https://enduravita.eu/products/nmn-pure-powder/?sca_ref=6527249.kOBQqzVXSV @HOME LONGEVITY TEST: NAD+ Spiegel testen: Nutze den CODE "ELISABETHEBERL" und diesen Link für 15% Rabatt (*): ➤ https://avea-life.com/products/longevity-nad-test?sub_id=ELISABETHEBERL ....................................................................................................................................................... Nicht Altern - Lachssperma wie Kim Kardashian? ➤ https://youtu.be/ASIp9hamiFk Zellalterung stoppen mit NMN: ➤ https://youtu.be/-9J2_Go0Wic Alterung stoppen ohne BOTOX: ➤ https://youtu.be/B8xHzogWD2o Geheimnis ewiger Jugend von Kim Kardashian: ➤ https://youtu.be/9N1Aw1XNDGE Das High Performance Geheimnis von Top CEOS (kein Lachssperma) ➤ https://youtu.be/kASxnOiGiIs ....................................................................................................................................................... Mehr erfahren: https://bio.site/elisabetheberl International inquiries in English available. ....................................................................................................................................................... ➤ Instag https://www.youtube-nocookie.com/embed/GBB0qRyot5g 355 2024-09-26T07:58:32.000Z 2026-10-22T20:11:46.996Z https://longevityharbor.com/en/watch/GElNJLH8QcE IGF-1 Signaling: A Key Pathway in Cancer, Longevity & Drug Development https://i.ytimg.com/vi/GElNJLH8QcE/hqdefault.jpg The content of this video is based on Xu Y, Wei J, Wang W, Mao Z, Wang D, Zhang T, Zhang P. Oleanolic Acid Slows Down Aging Through IGF-1 Affecting the PI3K/AKT/mTOR Signaling Pathway. Molecules. 2025 Feb 6;30(3):740. doi: 10.3390/molecules30030740. PMID: 39942843; PMCID: PMC11820160. The IGF-1 signaling pathway plays a crucial role in cell proliferation, longevity, and DNA repair, making it a key target for cancer therapy and anti-aging research. In this video, we break down how IGF-1 activates the PI3K-AKT-mTOR pathway, driving DNA replication and cell growth. We also explore how targeted therapies, such as IGF-1R and mTOR inhibitors, are being developed to suppress tumor growth and enhance longevity. Understanding this pathway opens new doors for precision medicine in cancer, aging-related disorders, and metabolic diseases. Watch now to learn more! https://www.youtube-nocookie.com/embed/GElNJLH8QcE 136 2025-02-15T15:18:29.000Z 2026-10-22T19:32:36.461Z https://longevityharbor.com/de/watch/GElNJLH8QcE IGF-1 Signaling: A Key Pathway in Cancer, Longevity & Drug Development https://i.ytimg.com/vi/GElNJLH8QcE/hqdefault.jpg The content of this video is based on Xu Y, Wei J, Wang W, Mao Z, Wang D, Zhang T, Zhang P. Oleanolic Acid Slows Down Aging Through IGF-1 Affecting the PI3K/AKT/mTOR Signaling Pathway. Molecules. 2025 Feb 6;30(3):740. doi: 10.3390/molecules30030740. PMID: 39942843; PMCID: PMC11820160. The IGF-1 signaling pathway plays a crucial role in cell proliferation, longevity, and DNA repair, making it a key target for cancer therapy and anti-aging research. In this video, we break down how IGF-1 activates the PI3K-AKT-mTOR pathway, driving DNA replication and cell growth. We also explore how targeted therapies, such as IGF-1R and mTOR inhibitors, are being developed to suppress tumor growth and enhance longevity. Understanding this pathway opens new doors for precision medicine in cancer, aging-related disorders, and metabolic diseases. Watch now to learn more! https://www.youtube-nocookie.com/embed/GElNJLH8QcE 136 2025-02-15T15:18:29.000Z 2026-10-22T19:32:36.461Z https://longevityharbor.com/en/watch/GEnnAe8vHAI 🦷Longevity beginnt im Mund!Wie gesunde Zähne Dein biologisches Altern beeinflussen können#longevity https://i.ytimg.com/vi/GEnnAe8vHAI/hqdefault.jpg Was, wenn ein entscheidender Schlüssel für ein langes, gesundes Leben direkt in Deinem Mund liegt? Wir achten auf gesunde Ernährung, optimieren unseren Schlaf und trainieren für mehr Energie und Fitness. Doch die Zahngesundheit wird im Longevity-Konzept häufig unterschätzt. Dabei können chronische Entzündungen im Mundraum mit Entzündungsprozessen im gesamten Körper zusammenhängen – und damit auch für unsere langfristige Gesundheit eine wichtige Rolle spielen. 🔎 Stille Entzündungen, Zahnfleischgesundheit und biologisches Altern: Welche Zusammenhänge gibt es zwischen Mundgesundheit, Immunsystem und Longevity? Welche Risiken bleiben lange unbemerkt? Und was können wir selbst tun, um unsere Zähne und unsere Gesundheit möglichst lange zu erhalten? Ich treffe Dr. Moritz Kneer von der Swiss Biohealth Clinic am Bodensee. Gemeinsam sprechen wir über die faszinierende Verbindung zwischen biologischer Zahngesundheit, chronischen Entzündungen und gesundem Altern. 🦷 In diesem Talk erfährst Du: Warum gesunde Zähne und gesundes Zahnfleisch für die Longevity wichtig sind? Welche Rolle Parodontitis und chronische Entzündungen spielen können? Was hinter dem Begriff „Silent Inflammation“ steckt? Wie Mundgesundheit und biologisches Altern zusammenhängen Worauf Du achten kannst, um Deine Zahngesundheit langfristig zu schützen Longevity ist mehr als Ernährung, Schlaf und Bewegung – auch Deine Mundgesundheit verdient Aufmerksamkeit! ▶️ Sieh Dir jetzt unseren Talk mit Dr. Moritz Kneer an und entdecke, warum gesunde Zähne ein wichtiger Baustein für ein langes, gesundes Leben sein können. Bleibt dran und abonniere unseren Kanal für tägliche spannende Tipps für ein glückliches, gesundes und lange Leben #longevity #zahngesundheit #biologischesaltern #mundgesundheit #silentinflammation #parodontitis #gesundaltern #swiss #bodensee #gesundheit #vital#chronischeentzündungen https://www.youtube-nocookie.com/embed/GEnnAe8vHAI 525 2026-10-21T05:26:28.000Z 2026-10-22T20:11:49.213Z https://longevityharbor.com/de/watch/GEnnAe8vHAI 🦷Longevity beginnt im Mund!Wie gesunde Zähne Dein biologisches Altern beeinflussen können#longevity https://i.ytimg.com/vi/GEnnAe8vHAI/hqdefault.jpg Was, wenn ein entscheidender Schlüssel für ein langes, gesundes Leben direkt in Deinem Mund liegt? Wir achten auf gesunde Ernährung, optimieren unseren Schlaf und trainieren für mehr Energie und Fitness. Doch die Zahngesundheit wird im Longevity-Konzept häufig unterschätzt. Dabei können chronische Entzündungen im Mundraum mit Entzündungsprozessen im gesamten Körper zusammenhängen – und damit auch für unsere langfristige Gesundheit eine wichtige Rolle spielen. 🔎 Stille Entzündungen, Zahnfleischgesundheit und biologisches Altern: Welche Zusammenhänge gibt es zwischen Mundgesundheit, Immunsystem und Longevity? Welche Risiken bleiben lange unbemerkt? Und was können wir selbst tun, um unsere Zähne und unsere Gesundheit möglichst lange zu erhalten? Ich treffe Dr. Moritz Kneer von der Swiss Biohealth Clinic am Bodensee. Gemeinsam sprechen wir über die faszinierende Verbindung zwischen biologischer Zahngesundheit, chronischen Entzündungen und gesundem Altern. 🦷 In diesem Talk erfährst Du: Warum gesunde Zähne und gesundes Zahnfleisch für die Longevity wichtig sind? Welche Rolle Parodontitis und chronische Entzündungen spielen können? Was hinter dem Begriff „Silent Inflammation“ steckt? Wie Mundgesundheit und biologisches Altern zusammenhängen Worauf Du achten kannst, um Deine Zahngesundheit langfristig zu schützen Longevity ist mehr als Ernährung, Schlaf und Bewegung – auch Deine Mundgesundheit verdient Aufmerksamkeit! ▶️ Sieh Dir jetzt unseren Talk mit Dr. Moritz Kneer an und entdecke, warum gesunde Zähne ein wichtiger Baustein für ein langes, gesundes Leben sein können. Bleibt dran und abonniere unseren Kanal für tägliche spannende Tipps für ein glückliches, gesundes und lange Leben #longevity #zahngesundheit #biologischesaltern #mundgesundheit #silentinflammation #parodontitis #gesundaltern #swiss #bodensee #gesundheit #vital#chronischeentzündungen https://www.youtube-nocookie.com/embed/GEnnAe8vHAI 525 2026-10-21T05:26:28.000Z 2026-10-22T20:11:49.213Z https://longevityharbor.com/en/watch/GHf5VWmpRmA Video description: why adults over 60 may wake around 3 AM https://i.ytimg.com/vi/GHf5VWmpRmA/hqdefault.jpg The description attributes night-time awakenings in people over 60 to possible shifts in the body clock, less deep sleep, melatonin changes or bladder health, and cites a study linking bathroom trips to 54.2% of awakenings in older adults with insomnia. https://www.youtube-nocookie.com/embed/GHf5VWmpRmA 912 2026-10-10T13:00:09.000Z 2026-10-22T21:11:17.919Z https://longevityharbor.com/de/watch/GHf5VWmpRmA Videobeschreibung: Warum Erwachsene über 60 gegen 3 Uhr aufwachen können https://i.ytimg.com/vi/GHf5VWmpRmA/hqdefault.jpg Die Beschreibung führt nächtliches Aufwachen bei Menschen über 60 auf mögliche Verschiebungen der inneren Uhr, weniger Tiefschlaf, Melatoninveränderungen oder Blasengesundheit zurück und nennt eine Studie, die Toilettengänge mit 54,2 % der Aufwachphasen bei älteren Erwachsenen mit Insomnie verband. https://www.youtube-nocookie.com/embed/GHf5VWmpRmA 912 2026-10-10T13:00:09.000Z 2026-10-22T21:11:17.919Z https://longevityharbor.com/en/watch/GIU0bzi1I2Q Tipps für gesundes Altern: Ernährungsmedizinerin und Autorin Dr. Yael Adler | PODCAST Aus dem Leben https://i.ytimg.com/vi/GIU0bzi1I2Q/hqdefault.jpg Viele haben Angst vor dem Alter, aber es gehört nun einmal dazu, wenn man lange leben will. Die gute Nachricht: Wir können einiges dafür tun, um möglichst lange gesund und fit zu bleiben. Denn wie und in welchem Tempo wir alt werden, hängt maximal zu 30 Prozent von unseren Genen ab. Den Rest haben wir aber zu großen Teilen selbst in der Hand. Was wir tun können, um möglichst gesund und fit alt zu werden, dieser Frage ist die bekannte Ärztin und Ernährungsmedizinerin Dr. Yael Adler in ihrem Buch „Genial Vital“ nachgegangen. Ihre Antworten darauf und viele praktische Tipps, teilt sie in SR 3 „Aus dem Leben“. Mit Gastgeber Uwe Jäger hat sich die Bestsellerautorin Yael Adler außerdem darüber unterhalten, warum das Alter noch immer ein Tabu ist und warum Tomatenmark und Karottensaft besser sind als fast jedes Anti-Aging-Mittel. Diese Folge von "Aus dem Leben" ist am 2.1.2024 auf SR 3 Saarlandwelle ausgestrahlt worden. ----- Über diesen Youtube-Kanal ----- Im Youtube-Channel des Saarländischen Rundfunks (SR) finden Sie ausgewählte Beiträge und Sendungen des SR. Schwerpunkt der Berichterstattung sind das Saarland und die Großregion. Alle Infos vom und zum Saarländischen Rundfunk: https://SR.de Die SR-Mediathek finden Sie hier: https://SR-Mediathek.de Den Youtube-Channel des Saarländischen Rundfunks können Sie hier abonnieren: https://www.youtube.com/channel/UCnFrQ2IXQlW6sFPe4ys09rQ?sub_confirmation=1 https://www.youtube-nocookie.com/embed/GIU0bzi1I2Q 3059 2024-01-03T18:00:06.000Z 2026-10-22T18:43:10.804Z https://longevityharbor.com/de/watch/GIU0bzi1I2Q Tipps für gesundes Altern: Ernährungsmedizinerin und Autorin Dr. Yael Adler | PODCAST Aus dem Leben https://i.ytimg.com/vi/GIU0bzi1I2Q/hqdefault.jpg Viele haben Angst vor dem Alter, aber es gehört nun einmal dazu, wenn man lange leben will. Die gute Nachricht: Wir können einiges dafür tun, um möglichst lange gesund und fit zu bleiben. Denn wie und in welchem Tempo wir alt werden, hängt maximal zu 30 Prozent von unseren Genen ab. Den Rest haben wir aber zu großen Teilen selbst in der Hand. Was wir tun können, um möglichst gesund und fit alt zu werden, dieser Frage ist die bekannte Ärztin und Ernährungsmedizinerin Dr. Yael Adler in ihrem Buch „Genial Vital“ nachgegangen. Ihre Antworten darauf und viele praktische Tipps, teilt sie in SR 3 „Aus dem Leben“. Mit Gastgeber Uwe Jäger hat sich die Bestsellerautorin Yael Adler außerdem darüber unterhalten, warum das Alter noch immer ein Tabu ist und warum Tomatenmark und Karottensaft besser sind als fast jedes Anti-Aging-Mittel. Diese Folge von "Aus dem Leben" ist am 2.1.2024 auf SR 3 Saarlandwelle ausgestrahlt worden. ----- Über diesen Youtube-Kanal ----- Im Youtube-Channel des Saarländischen Rundfunks (SR) finden Sie ausgewählte Beiträge und Sendungen des SR. Schwerpunkt der Berichterstattung sind das Saarland und die Großregion. Alle Infos vom und zum Saarländischen Rundfunk: https://SR.de Die SR-Mediathek finden Sie hier: https://SR-Mediathek.de Den Youtube-Channel des Saarländischen Rundfunks können Sie hier abonnieren: https://www.youtube.com/channel/UCnFrQ2IXQlW6sFPe4ys09rQ?sub_confirmation=1 https://www.youtube-nocookie.com/embed/GIU0bzi1I2Q 3059 2024-01-03T18:00:06.000Z 2026-10-22T18:43:10.804Z https://longevityharbor.com/en/watch/GMhDMPuskFw Gesund altern: 7 Lebensmittel für starke Muskeln und ein waches Gedächtnis https://i.ytimg.com/vi/GMhDMPuskFw/hqdefault.jpg Welche Lebensmittel unterstützen Ihren Körper ab 60 wirklich? In diesem Video zeige ich Ihnen 7 einfache, bezahlbare Lebensmittel für starke Muskeln, Knochen, Herz und Gehirn – und Nummer 1 steht wahrscheinlich schon in Ihrer Küche. In diesem Video: ✔ Warum sich der Körper ab 60 verändert ✔ 7 Lebensmittel für mehr Kraft und Energie im Alter ✔ Günstige Alternativen, wenn das Budget knapp ist ✔ Warum Bewegung genauso wichtig ist wie die Ernährung ⏱ Kapitel: Warum Sie das wissen sollten Nr. 7: Beeren Nr. 6: Naturjoghurt & Quark Nr. 5: Haferflocken Nr. 4: Blattgemüse Nr. 3: Eier Nr. 2: Fetter Fisch Nr. 1: Walnüsse & Olivenöl Günstig einkaufen & Bewegung Zusammenfassung 👉 Abonnieren Sie Gesund & Stark für mehr Tipps rund um Gesundheit und Ernährung ab 60. ⚠️ Hinweis: Dieses Video dient nur der allgemeinen Information und ersetzt keine ärztliche Beratung. Sprechen Sie vor einer Ernährungsumstellung mit Ihrer Ärztin oder Ihrem Arzt, besonders wenn Sie Medikamente einnehmen oder Nieren-, Herz- oder Zuckerprobleme haben. #Ernährung #Senioren #Gesundheit https://www.youtube-nocookie.com/embed/GMhDMPuskFw 493 2026-10-04T03:30:21.000Z 2026-10-22T18:43:10.923Z https://longevityharbor.com/de/watch/GMhDMPuskFw Gesund altern: 7 Lebensmittel für starke Muskeln und ein waches Gedächtnis https://i.ytimg.com/vi/GMhDMPuskFw/hqdefault.jpg Welche Lebensmittel unterstützen Ihren Körper ab 60 wirklich? In diesem Video zeige ich Ihnen 7 einfache, bezahlbare Lebensmittel für starke Muskeln, Knochen, Herz und Gehirn – und Nummer 1 steht wahrscheinlich schon in Ihrer Küche. In diesem Video: ✔ Warum sich der Körper ab 60 verändert ✔ 7 Lebensmittel für mehr Kraft und Energie im Alter ✔ Günstige Alternativen, wenn das Budget knapp ist ✔ Warum Bewegung genauso wichtig ist wie die Ernährung ⏱ Kapitel: Warum Sie das wissen sollten Nr. 7: Beeren Nr. 6: Naturjoghurt & Quark Nr. 5: Haferflocken Nr. 4: Blattgemüse Nr. 3: Eier Nr. 2: Fetter Fisch Nr. 1: Walnüsse & Olivenöl Günstig einkaufen & Bewegung Zusammenfassung 👉 Abonnieren Sie Gesund & Stark für mehr Tipps rund um Gesundheit und Ernährung ab 60. ⚠️ Hinweis: Dieses Video dient nur der allgemeinen Information und ersetzt keine ärztliche Beratung. Sprechen Sie vor einer Ernährungsumstellung mit Ihrer Ärztin oder Ihrem Arzt, besonders wenn Sie Medikamente einnehmen oder Nieren-, Herz- oder Zuckerprobleme haben. #Ernährung #Senioren #Gesundheit https://www.youtube-nocookie.com/embed/GMhDMPuskFw 493 2026-10-04T03:30:21.000Z 2026-10-22T18:43:10.923Z https://longevityharbor.com/en/watch/GOWrA3F_Wlw I'm 46 — These 7 Exercises Are Reversing My Aging https://i.ytimg.com/vi/GOWrA3F_Wlw/hqdefault.jpg Most people believe getting older automatically means getting weaker, stiffer, and less independent. The research says otherwise — and these 7 exercises are the exact ones used personally and with clients ranging from their 30s to their 70s to meaningfully reverse physical decline most people accept as inevitable. In this video, I break down each exercise with beginner, intermediate, and advanced progressions, along with the specific longevity research behind why each one matters more than most people realize. You'll learn: ✅ Why grip strength is used as an actual biomarker for longevity ✅ The Japanese interval walking protocol shown to reverse cardiovascular aging ✅ Why the deep squat is a survival skill, not just a stretch ✅ The study linking floor sit-to-stand ability to a 5x higher death risk ✅ The "world's greatest stretch" that targets every joint that stiffens first with age ✅ Why cardiorespiratory fitness predicts lifespan better than smoking status ✅ Why power declines twice as fast as strength after 40 (and how to rebuild it) ✅ Why loaded carries may be one of the best exercises for spinal stability These aren't fitness trends. They're research-backed movement patterns that determine how well you age — and applied consistently, they can make you measurably more capable in the decades ahead than you are today. Watch till the end for the complete breakdown of all 7 exercises and progressions. 00:00 – Why aging doesn't have to mean decline 00:30 – Meet the 46-year-old trainer behind these 7 exercises 01:00 – Exercise 1: Bar hang (grip strength & longevity research) 02:20 – Exercise 2: Japanese interval walking protocol 03:50 – Exercise 3: The deep squat (the 5x mortality study) 05:20 – Exercise 4: World's greatest stretch for aging joints 06:30 – Exercise 5: Zone 2 cardio and mitochondrial health 08:00 – Exercise 6: Plyometric training and power loss after 40 09:30 – Exercise 7: Loaded carries for full-body integrity 10:50 – Why these are non-negotiable, not optional 11:20 – Final takeaway: becoming m https://www.youtube-nocookie.com/embed/GOWrA3F_Wlw 643 2026-08-02T01:15:23.000Z 2026-10-22T18:32:08.274Z https://longevityharbor.com/de/watch/GOWrA3F_Wlw I'm 46 — These 7 Exercises Are Reversing My Aging https://i.ytimg.com/vi/GOWrA3F_Wlw/hqdefault.jpg Most people believe getting older automatically means getting weaker, stiffer, and less independent. The research says otherwise — and these 7 exercises are the exact ones used personally and with clients ranging from their 30s to their 70s to meaningfully reverse physical decline most people accept as inevitable. In this video, I break down each exercise with beginner, intermediate, and advanced progressions, along with the specific longevity research behind why each one matters more than most people realize. You'll learn: ✅ Why grip strength is used as an actual biomarker for longevity ✅ The Japanese interval walking protocol shown to reverse cardiovascular aging ✅ Why the deep squat is a survival skill, not just a stretch ✅ The study linking floor sit-to-stand ability to a 5x higher death risk ✅ The "world's greatest stretch" that targets every joint that stiffens first with age ✅ Why cardiorespiratory fitness predicts lifespan better than smoking status ✅ Why power declines twice as fast as strength after 40 (and how to rebuild it) ✅ Why loaded carries may be one of the best exercises for spinal stability These aren't fitness trends. They're research-backed movement patterns that determine how well you age — and applied consistently, they can make you measurably more capable in the decades ahead than you are today. Watch till the end for the complete breakdown of all 7 exercises and progressions. 00:00 – Why aging doesn't have to mean decline 00:30 – Meet the 46-year-old trainer behind these 7 exercises 01:00 – Exercise 1: Bar hang (grip strength & longevity research) 02:20 – Exercise 2: Japanese interval walking protocol 03:50 – Exercise 3: The deep squat (the 5x mortality study) 05:20 – Exercise 4: World's greatest stretch for aging joints 06:30 – Exercise 5: Zone 2 cardio and mitochondrial health 08:00 – Exercise 6: Plyometric training and power loss after 40 09:30 – Exercise 7: Loaded carries for full-body integrity 10:50 – Why these are non-negotiable, not optional 11:20 – Final takeaway: becoming m https://www.youtube-nocookie.com/embed/GOWrA3F_Wlw 643 2026-08-02T01:15:23.000Z 2026-10-22T18:32:08.274Z https://longevityharbor.com/en/watch/GSNWvvkLlm4 Video description on diet and healthy ageing: foods, sugar–Alzheimer claims and lithium in water https://i.ytimg.com/vi/GSNWvvkLlm4/hqdefault.jpg The description says the video examines what research actually says about nutrition and healthy ageing: vegetables, fruit, whole grains, legumes, nuts and unsaturated fats, plus sugar and the often-claimed Alzheimer link and lithium in drinking water. It says single superfoods or supplements are no shortcut and the long-term dietary pattern probably matters more. https://www.youtube-nocookie.com/embed/GSNWvvkLlm4 345 2026-10-07T15:00:06.000Z 2026-10-22T21:13:01.196Z https://longevityharbor.com/de/watch/GSNWvvkLlm4 Videobeschreibung zu Ernährung und gesundem Altern: Lebensmittel, Zucker-Alzheimer-Behauptungen und https://i.ytimg.com/vi/GSNWvvkLlm4/hqdefault.jpg Laut Beschreibung prüft das Video, was die Forschung tatsächlich über Ernährung und gesundes Altern sagt: Gemüse, Obst, Vollkornprodukte, Hülsenfrüchte, Nüsse und ungesättigte Fette sowie Zucker und den oft behaupteten Alzheimer-Zusammenhang und Lithium im Trinkwasser. Einzelne Superfoods oder Supplements seien keine Abkürzung, und das langfristige Ernährungsmuster sei wahrscheinlich wichtiger. https://www.youtube-nocookie.com/embed/GSNWvvkLlm4 345 2026-10-07T15:00:06.000Z 2026-10-22T21:13:01.196Z https://longevityharbor.com/en/watch/GTGnEFaBhwA Immunologist Alan Landay discusses inflammaging and immune aging in a video conversation https://i.ytimg.com/vi/GTGnEFaBhwA/hqdefault.jpg In this Decoding Longevity episode description, Raghav Sehgal and Macsue Jacques talk with immunologist Alan Landay about how chronic immune activation, gut microbiome disruption and systemic inflammation are described as contributing to accelerated aging, with insights said to come from HIV research and to apply broadly. https://www.youtube-nocookie.com/embed/GTGnEFaBhwA 1457 2026-02-18T16:30:06.000Z 2026-10-23T02:27:58.743Z https://longevityharbor.com/de/watch/GTGnEFaBhwA Immunologe Alan Landay spricht in einem Videogespräch über Inflammaging und Immunalterung https://i.ytimg.com/vi/GTGnEFaBhwA/hqdefault.jpg In der Beschreibung dieser Decoding-Longevity-Episode sprechen Raghav Sehgal und Macsue Jacques mit dem Immunologen Alan Landay darüber, wie chronische Immunaktivierung, Störungen des Darmmikrobioms und systemische Entzündung als Beiträge zu beschleunigter Alterung beschrieben werden; die Erkenntnisse stammen laut Beschreibung aus der HIV-Forschung und sollen breit gelten. https://www.youtube-nocookie.com/embed/GTGnEFaBhwA 1457 2026-02-18T16:30:06.000Z 2026-10-23T02:27:58.743Z https://longevityharbor.com/en/watch/GU-Zc1eR9N4 What is “epigenetic aging” and how can we measure it? #epigenetics #age #DNA #methylation #biology https://i.ytimg.com/vi/GU-Zc1eR9N4/hqdefault.jpg What is “epigenetic aging” and how can we measure it? #epigenetics #age #DNA #methylation #biology #biologicalclock #Horvath #science #research #aging https://www.youtube-nocookie.com/embed/GU-Zc1eR9N4 99 2025-05-01T14:03:24.000Z 2026-10-22T17:11:30.669Z https://longevityharbor.com/de/watch/GU-Zc1eR9N4 What is “epigenetic aging” and how can we measure it? #epigenetics #age #DNA #methylation #biology https://i.ytimg.com/vi/GU-Zc1eR9N4/hqdefault.jpg What is “epigenetic aging” and how can we measure it? #epigenetics #age #DNA #methylation #biology #biologicalclock #Horvath #science #research #aging https://www.youtube-nocookie.com/embed/GU-Zc1eR9N4 99 2025-05-01T14:03:24.000Z 2026-10-22T17:11:30.669Z https://longevityharbor.com/en/watch/GaLYiLU77HU A Neuroscientist Reveals The Diet That Doubles Autophagy Beyond Fasting. https://i.ytimg.com/vi/GaLYiLU77HU/hqdefault.jpg A Neuroscientist Reveals The Diet That Doubles Autophagy Beyond Fasting. Neuroscientist Reveals Diet that Doubles Autophagy More than Fasting 🧠✨ 🧬 Ready to UNLOCK your body's most powerful cellular renewal system? In this groundbreaking video, a neuroscientist reveals the revolutionary diet strategy that can DOUBLE autophagy, your body's "self-cleaning" mode, achieving even more than fasting alone. 🧼 We're diving deep into the science of cellular cleanup and why the classic approach to fasting might not be the ultimate solution. 🔍 In this video, you will discover: • The SHOCKING TRUTH about fasting and autophagy that most people don't know. 🤯 • The specific cellular "master switch" (mTOR) that controls growth vs. cleanup. 🔄 • The powerful dietary protocol that keeps autophagy active even while you eat. 🍽️ • Why Protein Cycling is the key to sustained cellular renewal and longevity. 📈 • The exact foods to eat (and avoid) to maximize your body's innate cleansing processes. 🥦 • Practical, step-by-step guidance on implementing this diet into your weekly routine. 🗓️ This isn't just another diet trend—it's a data-backed, science-driven approach to taking control of your health at a fundamental level. We'll explore the cutting-edge research from leading journals that shows how this specific dietary pattern can enhance brain health, support metabolic function, and promote longevity more effectively than traditional fasting methods. 🧪📚 ✨ FREE RESOURCE! Download your FREE "Autophagy Diet Guide" with a simple meal plan and food list to get started today! 👉 [LINK HERE] 💬 Join the Conversation! What's your biggest challenge with diet and longevity? Let me know in the comments below! 👇 your queries Autophagy Neuroscientist Diet Doubles Autophagy Fasting Cellular Renewal Self-Cleaning Science mTOR Protein Cycling Cellular Cleanup Longevity Health Optimization Cellular Health Nutrition Biohacking Brain Health Meal Plan Food List Health Wellness Healthy Eating Groundbreaking Revolutionary Strategy Data-Back https://www.youtube-nocookie.com/embed/GaLYiLU77HU 1524 2025-11-13T19:00:14.000Z 2026-10-22T19:32:32.163Z https://longevityharbor.com/de/watch/GaLYiLU77HU A Neuroscientist Reveals The Diet That Doubles Autophagy Beyond Fasting. https://i.ytimg.com/vi/GaLYiLU77HU/hqdefault.jpg A Neuroscientist Reveals The Diet That Doubles Autophagy Beyond Fasting. Neuroscientist Reveals Diet that Doubles Autophagy More than Fasting 🧠✨ 🧬 Ready to UNLOCK your body's most powerful cellular renewal system? In this groundbreaking video, a neuroscientist reveals the revolutionary diet strategy that can DOUBLE autophagy, your body's "self-cleaning" mode, achieving even more than fasting alone. 🧼 We're diving deep into the science of cellular cleanup and why the classic approach to fasting might not be the ultimate solution. 🔍 In this video, you will discover: • The SHOCKING TRUTH about fasting and autophagy that most people don't know. 🤯 • The specific cellular "master switch" (mTOR) that controls growth vs. cleanup. 🔄 • The powerful dietary protocol that keeps autophagy active even while you eat. 🍽️ • Why Protein Cycling is the key to sustained cellular renewal and longevity. 📈 • The exact foods to eat (and avoid) to maximize your body's innate cleansing processes. 🥦 • Practical, step-by-step guidance on implementing this diet into your weekly routine. 🗓️ This isn't just another diet trend—it's a data-backed, science-driven approach to taking control of your health at a fundamental level. We'll explore the cutting-edge research from leading journals that shows how this specific dietary pattern can enhance brain health, support metabolic function, and promote longevity more effectively than traditional fasting methods. 🧪📚 ✨ FREE RESOURCE! Download your FREE "Autophagy Diet Guide" with a simple meal plan and food list to get started today! 👉 [LINK HERE] 💬 Join the Conversation! What's your biggest challenge with diet and longevity? Let me know in the comments below! 👇 your queries Autophagy Neuroscientist Diet Doubles Autophagy Fasting Cellular Renewal Self-Cleaning Science mTOR Protein Cycling Cellular Cleanup Longevity Health Optimization Cellular Health Nutrition Biohacking Brain Health Meal Plan Food List Health Wellness Healthy Eating Groundbreaking Revolutionary Strategy Data-Back https://www.youtube-nocookie.com/embed/GaLYiLU77HU 1524 2025-11-13T19:00:14.000Z 2026-10-22T19:32:32.163Z https://longevityharbor.com/en/watch/GcW5MFOzIK4 How Fast Are You Really Aging? | DunedinPACE Epigenetic Clock Explained https://i.ytimg.com/vi/GcW5MFOzIK4/hqdefault.jpg Ever wondered why some people thrive well into their 80s while others struggle much sooner? In this video, TruDiagnostic breaks down DunedinPACE—the first “speedometer” for biological aging that shows how fast (or slow) your body is aging right now, not just how old it looks on paper. What you’ll learn: 00:00 – Why chronological age is only part of the story 00:42 – The rise of epigenetic aging clocks 01:30 – How DunedinPACE measures aging speed, not age 02:20 – Inside the 20-year Dunedin Study (1,000 participants) 03:35 – Why shared life experiences matter for accurate results 04:40 – DNA methylation: tiny tags that reveal lifestyle impact 05:25 – Real-world uses: smoking cessation, sleep, diet & more 06:10 – The future: extending health-span, not just lifespan About DunedinPACE Built on decades of longitudinal data, DunedinPACE analyzes DNA methylation patterns from a single blood sample, giving researchers and clinicians an instant readout of your current pace of aging. Interested in testing your own Aging Speed? Visit https://trudiagnostic.com to learn about our at-home epigenetic testing kits and professional lab services. Like this video if you’re passionate about longevity science, subscribe for more cutting-edge insights, and hit the bell so you never miss an update. #DunedinPACE #TruDiagnostic #Epigenetics #BiologicalAge #Longevity #Healthspan Follow us: Facebook: https://www.facebook.com/TruDiagnostic Instagram: https://www.instagram.com/trudiagnosticofficial/ Pinterest: https://www.pinterest.com/trudiagnostic/ Twitter: https://twitter.com/TruDiagnostic https://www.youtube-nocookie.com/embed/GcW5MFOzIK4 381 2025-06-06T14:43:33.000Z 2026-10-22T17:43:35.235Z https://longevityharbor.com/de/watch/GcW5MFOzIK4 How Fast Are You Really Aging? | DunedinPACE Epigenetic Clock Explained https://i.ytimg.com/vi/GcW5MFOzIK4/hqdefault.jpg Ever wondered why some people thrive well into their 80s while others struggle much sooner? In this video, TruDiagnostic breaks down DunedinPACE—the first “speedometer” for biological aging that shows how fast (or slow) your body is aging right now, not just how old it looks on paper. What you’ll learn: 00:00 – Why chronological age is only part of the story 00:42 – The rise of epigenetic aging clocks 01:30 – How DunedinPACE measures aging speed, not age 02:20 – Inside the 20-year Dunedin Study (1,000 participants) 03:35 – Why shared life experiences matter for accurate results 04:40 – DNA methylation: tiny tags that reveal lifestyle impact 05:25 – Real-world uses: smoking cessation, sleep, diet & more 06:10 – The future: extending health-span, not just lifespan About DunedinPACE Built on decades of longitudinal data, DunedinPACE analyzes DNA methylation patterns from a single blood sample, giving researchers and clinicians an instant readout of your current pace of aging. Interested in testing your own Aging Speed? Visit https://trudiagnostic.com to learn about our at-home epigenetic testing kits and professional lab services. Like this video if you’re passionate about longevity science, subscribe for more cutting-edge insights, and hit the bell so you never miss an update. #DunedinPACE #TruDiagnostic #Epigenetics #BiologicalAge #Longevity #Healthspan Follow us: Facebook: https://www.facebook.com/TruDiagnostic Instagram: https://www.instagram.com/trudiagnosticofficial/ Pinterest: https://www.pinterest.com/trudiagnostic/ Twitter: https://twitter.com/TruDiagnostic https://www.youtube-nocookie.com/embed/GcW5MFOzIK4 381 2025-06-06T14:43:33.000Z 2026-10-22T17:43:35.235Z https://longevityharbor.com/en/watch/GdcnaNW8I3w Ep. 13 | The Roadmap to Precision Geromedicine with Prof. Andrea B . Maier https://i.ytimg.com/vi/GdcnaNW8I3w/hqdefault.jpg What if we could redefine the future of aging through precision? In this episode of Decoding Longevity, hosts Raghav Sehgal and Macsue Jacques sit down with Prof. Andrea B. Maier, a world leader in geriatric medicine and longevity science, to dive into the concept of precision geromedicine. Together, we discuss: • How precision medicine principles apply to aging and longevity • The role of genetics, biomarkers, and lifestyle in tailoring interventions • Why a “one-size-fits-all” approach no longer works in geroscience • The promise of multi-organ, data-driven models for personalized care Prof. Maier shares her vision for a future where healthcare doesn’t just treat disease—it prevents it, delays it, and optimizes quality of life at every stage. 🔔 Subscribe to Decoding Longevity for more insights into the science shaping the future of health and aging. #Longevity #AgingScience #PrecisionMedicine #Geromedicine #DecodingLongevity https://www.youtube-nocookie.com/embed/GdcnaNW8I3w 2185 2025-09-10T16:50:13.000Z 2026-10-22T19:54:20.175Z https://longevityharbor.com/de/watch/GdcnaNW8I3w Ep. 13 | The Roadmap to Precision Geromedicine with Prof. Andrea B . Maier https://i.ytimg.com/vi/GdcnaNW8I3w/hqdefault.jpg What if we could redefine the future of aging through precision? In this episode of Decoding Longevity, hosts Raghav Sehgal and Macsue Jacques sit down with Prof. Andrea B. Maier, a world leader in geriatric medicine and longevity science, to dive into the concept of precision geromedicine. Together, we discuss: • How precision medicine principles apply to aging and longevity • The role of genetics, biomarkers, and lifestyle in tailoring interventions • Why a “one-size-fits-all” approach no longer works in geroscience • The promise of multi-organ, data-driven models for personalized care Prof. Maier shares her vision for a future where healthcare doesn’t just treat disease—it prevents it, delays it, and optimizes quality of life at every stage. 🔔 Subscribe to Decoding Longevity for more insights into the science shaping the future of health and aging. #Longevity #AgingScience #PrecisionMedicine #Geromedicine #DecodingLongevity https://www.youtube-nocookie.com/embed/GdcnaNW8I3w 2185 2025-09-10T16:50:13.000Z 2026-10-22T19:54:20.175Z https://longevityharbor.com/en/watch/Gkh7bx78zj8 Video description claims circadian rhythm can reverse biological aging https://i.ytimg.com/vi/Gkh7bx78zj8/hqdefault.jpg The description of this Reverse Age Academy video says circadian rhythm is an overlooked driver of aging and that light timing, dim evenings and warmer bulbs may support sleep, energy and recovery. It presents no study data, and the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/Gkh7bx78zj8 136 2026-04-14T09:41:09.000Z 2026-10-23T01:35:20.121Z https://longevityharbor.com/de/watch/Gkh7bx78zj8 Videobeschreibung behauptet, der circadiane Rhythmus könne biologisches Altern umkehren https://i.ytimg.com/vi/Gkh7bx78zj8/hqdefault.jpg Die Beschreibung dieses Videos von Reverse Age Academy nennt den circadianen Rhythmus einen übersehenen Alterungstreiber und behauptet, Lichtzeitpunkt, gedimmte Abende und wärmere Leuchtmittel könnten Schlaf, Energie und Erholung unterstützen. Sie enthält keine Studiendaten; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/Gkh7bx78zj8 136 2026-04-14T09:41:09.000Z 2026-10-23T01:35:20.121Z https://longevityharbor.com/en/watch/GlL1ggwX2jk How Real Science Unlocks Aging, Healthspan, and Longevity Secrets https://i.ytimg.com/vi/GlL1ggwX2jk/hqdefault.jpg Living longer isn’t just about adding years—it’s about adding life to those years. In this longevity science compilation, we explore cutting-edge research on aging, healthspan, lifespan extension, and biological age. No hype. No gimmicks. Just practical, evidence-based strategies to help you improve metabolic health, boost cellular health, reduce chronic inflammation, enhance mitochondrial function, slow biological aging, and live a longer, healthier life. Discover actionable insights on exercise for longevity, Omega-3 fats, inflammation control, plasma transfers, and more. Let’s make every moment count—and make every year stronger with smarter health optimization and longevity-focused habits. Chapters 00:00 – Intro: Real Science on Aging and Longevity 00:59 – Exercise vs Aging: Can Strength Training Fight Aging? 16:34 – Omega-3 vs Bryan Johnson’s $2M Protocol 30:15 – How Stress Damages DNA and Speeds Up Aging 47:42 – Exercise Reverses Genetic Signs of Aging 55:41 – microRNA in sEVs, and the Future of Anti-Aging Science #longevity #healthspan #agingresearch #antiaging #exerciseforlongevity, #strengthtraining #omega3 #bryanjohnson #aginggracefully #stressmanagement #dnahealth #genetichealth #reversingaging #lifespan #biohacking #healthoptimization #metabolichealth #wellnessjourney #mitochondrialhealth #scientificwellness #neuroscience #inflammation #lifespanextension #youthfulaging #resiliencelongevity #futureofmedicine #biologicalage #senolytics #chronologicalage #brainhealth #mentalhealth #vitality #antiinflammatorydiet #geroscience #staycurious https://www.youtube-nocookie.com/embed/GlL1ggwX2jk 4256 2025-05-07T11:00:23.000Z 2026-10-22T19:32:34.568Z https://longevityharbor.com/de/watch/GlL1ggwX2jk How Real Science Unlocks Aging, Healthspan, and Longevity Secrets https://i.ytimg.com/vi/GlL1ggwX2jk/hqdefault.jpg Living longer isn’t just about adding years—it’s about adding life to those years. In this longevity science compilation, we explore cutting-edge research on aging, healthspan, lifespan extension, and biological age. No hype. No gimmicks. Just practical, evidence-based strategies to help you improve metabolic health, boost cellular health, reduce chronic inflammation, enhance mitochondrial function, slow biological aging, and live a longer, healthier life. Discover actionable insights on exercise for longevity, Omega-3 fats, inflammation control, plasma transfers, and more. Let’s make every moment count—and make every year stronger with smarter health optimization and longevity-focused habits. Chapters 00:00 – Intro: Real Science on Aging and Longevity 00:59 – Exercise vs Aging: Can Strength Training Fight Aging? 16:34 – Omega-3 vs Bryan Johnson’s $2M Protocol 30:15 – How Stress Damages DNA and Speeds Up Aging 47:42 – Exercise Reverses Genetic Signs of Aging 55:41 – microRNA in sEVs, and the Future of Anti-Aging Science #longevity #healthspan #agingresearch #antiaging #exerciseforlongevity, #strengthtraining #omega3 #bryanjohnson #aginggracefully #stressmanagement #dnahealth #genetichealth #reversingaging #lifespan #biohacking #healthoptimization #metabolichealth #wellnessjourney #mitochondrialhealth #scientificwellness #neuroscience #inflammation #lifespanextension #youthfulaging #resiliencelongevity #futureofmedicine #biologicalage #senolytics #chronologicalage #brainhealth #mentalhealth #vitality #antiinflammatorydiet #geroscience #staycurious https://www.youtube-nocookie.com/embed/GlL1ggwX2jk 4256 2025-05-07T11:00:23.000Z 2026-10-22T19:32:34.568Z https://longevityharbor.com/en/watch/Gm626MgpveI Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation https://i.ytimg.com/vi/Gm626MgpveI/hqdefault.jpg Dr. Guido Kroemer is a professor at the University of Paris Descartes and an expert in immunology, cancer biology, aging, and autophagy. He is one of the most highly cited authors in the field of cell biology and was the most highly cited cell biologist for the period between 2007 and 2013. Especially notable among his contributions: he was the first to discover that the permeabilization of mitochondrial membranes is a concrete step towards apoptotic cell death. This episode is decidedly focused on autophagy, an important cellular program that is inducible by dietary fasting and has broad implications for aging and cancer. Autophagy discussion includes: • 00:04:44 - How the 3 main signals that activate autophagy all involve nutrient sensing. • 00:16:30 - The role of different types of fasting and nutrient deprivation in autophagy. • 00:24:35 - How different types of exercise can induce autophagy. • 00:32:04 - How a specific type of autophagy called mitophagy keeps mitochondria healthy. • 00:33:07 - How autophagy has been shown to slow cellular aging. • 00:35:13 - How autophagy prevents neurodegenerative diseases by clearing away protein aggregates. • 00:44:04 - The role of autophagy in cancer as a possible double-edged sword. • 00:50:27 - How certain compounds known as caloric restriction mimetics (or fasting mimetics) including resveratrol, spermidine, hydroxycitrate can induce autophagy by tricking the cell through the modulation of one or more of the 3 main autophagy signaling pathways. EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/guido-kroemer?utm_source=youtube&utm_medium=youtube&utm_campaign=kroemer_interview PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=kroemer_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/038-dr-guido-kroemer-on-autophagy-caloric-restriction/id818198322?i=1000532219751 Spotify: https://open.spotify.com/episode/3YCLWtMJo0e43rkxlRkTg2 Full interview playlis https://www.youtube-nocookie.com/embed/Gm626MgpveI 3944 2017-07-31T12:00:02.000Z 2026-10-22T17:43:38.446Z https://longevityharbor.com/de/watch/Gm626MgpveI Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation https://i.ytimg.com/vi/Gm626MgpveI/hqdefault.jpg Dr. Guido Kroemer is a professor at the University of Paris Descartes and an expert in immunology, cancer biology, aging, and autophagy. He is one of the most highly cited authors in the field of cell biology and was the most highly cited cell biologist for the period between 2007 and 2013. Especially notable among his contributions: he was the first to discover that the permeabilization of mitochondrial membranes is a concrete step towards apoptotic cell death. This episode is decidedly focused on autophagy, an important cellular program that is inducible by dietary fasting and has broad implications for aging and cancer. Autophagy discussion includes: • 00:04:44 - How the 3 main signals that activate autophagy all involve nutrient sensing. • 00:16:30 - The role of different types of fasting and nutrient deprivation in autophagy. • 00:24:35 - How different types of exercise can induce autophagy. • 00:32:04 - How a specific type of autophagy called mitophagy keeps mitochondria healthy. • 00:33:07 - How autophagy has been shown to slow cellular aging. • 00:35:13 - How autophagy prevents neurodegenerative diseases by clearing away protein aggregates. • 00:44:04 - The role of autophagy in cancer as a possible double-edged sword. • 00:50:27 - How certain compounds known as caloric restriction mimetics (or fasting mimetics) including resveratrol, spermidine, hydroxycitrate can induce autophagy by tricking the cell through the modulation of one or more of the 3 main autophagy signaling pathways. EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/guido-kroemer?utm_source=youtube&utm_medium=youtube&utm_campaign=kroemer_interview PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=kroemer_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/038-dr-guido-kroemer-on-autophagy-caloric-restriction/id818198322?i=1000532219751 Spotify: https://open.spotify.com/episode/3YCLWtMJo0e43rkxlRkTg2 Full interview playlis https://www.youtube-nocookie.com/embed/Gm626MgpveI 3944 2017-07-31T12:00:02.000Z 2026-10-22T17:43:38.446Z https://longevityharbor.com/en/watch/Gs5oUa0HZRk Video description: epigenetic clocks and biological age via DNA methylation https://i.ytimg.com/vi/Gs5oUa0HZRk/hqdefault.jpg The description says epigenetic clocks reveal biological age through DNA methylation and frames the video as decoding the science and economics of staying young. It gives no study details or results. https://www.youtube-nocookie.com/embed/Gs5oUa0HZRk 133 2026-09-17T21:00:35.000Z 2026-10-22T22:05:28.436Z https://longevityharbor.com/de/watch/Gs5oUa0HZRk Videobeschreibung: epigenetische Uhren und biologisches Alter über DNA-Methylierung https://i.ytimg.com/vi/Gs5oUa0HZRk/hqdefault.jpg Laut Beschreibung zeigen epigenetische Uhren das biologische Alter über DNA-Methylierung; das Video will die Wissenschaft und die Kosten des Jungbleibens entschlüsseln. Studiendetails oder Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/Gs5oUa0HZRk 133 2026-09-17T21:00:35.000Z 2026-10-22T22:05:28.436Z https://longevityharbor.com/en/watch/GsHEJwgG6k4 Altersforscher klärt auf: Können wir unsere biologische Uhr zurückdrehen? | Prof. Björn Schumacher https://i.ytimg.com/vi/GsHEJwgG6k4/hqdefault.jpg In dieser Episode spreche ich mit Prof. Björn Schumacher, Direktor des Instituts für Genomstabilität bei Alterung und Erkrankung am CECAD-Forschungszentrum der Universität Köln. Unser Thema: die Biologie des Alterns. Was passiert in unserem Körper, wenn wir älter werden – und was können wir aktiv tun, um diesen Prozess positiv zu beeinflussen? Neben bewährten Lebensstilfaktoren rücken zunehmend auch gezielte Interventionen wie Medikamente oder Nahrungsergänzungsmittel in den Fokus der Forschung. In dieser Folge erfährst du: ✅ Was beim Altern auf zellulärer Ebene wirklich passiert 💊 Welche Medikamente und Supplements gerade erforscht werden ⚠️ Warum manche „Anti-Aging“-Strategien mehr schaden als nutzen 🏋️‍♂️ Welche Rolle Lebensstil, Ernährung und Bewegung weiterhin spielen 🔬 Wie nah wir tatsächlich an einer gezielten „Verlangsamung des Alterns“ sind Modern Medicine lebt von der Unterstützung der Menschen, die diesen Podcast hören. Wenn du dazu beitragen willst, dass es weitergeht, und zusätzlich exklusive Bonusinhalte erhalten möchtest, kannst du mich hier supporten: ⁠⁠⁠⁠https://steady.page/modern-medicine⁠⁠⁠⁠ Kapitel: 00:00:00 Intro 00:00:50 Die Biologie des Alterns 00:05:30 Programmierter Prozess oder zufällige Schäden? 00:07:30 Genetik vs Umweltfaktoren 00:09:30 Faktoren, die das Altern beeinflussen 00:11:30 Kalorische Restriktion 00:15:00 Übergewicht 00:17:15 Chronologisches vs biologisches Alter 00:18:00 Können wir Altern messen? 00:20:30 Altersuhren: Epigenetische Muster 00:25:00 Alterstest für Verbraucher 00:30:00 Zukünftige Altersuhren 00:33:00 Medikamente gegen das Altern 00:33:30 Rapamycin 00:38:00 Mausstudien vs humane Studien 00:40:00 GLP-1 Agonisten (Abnehmsprritzen) 00:45:00 Metformin 00:50:00 Die wichtige Rolle der Muskelmasse 00:54:00 Resveratrol 00:57:30 NAD-Booster (NR, NMN) 01:00:00 NAD-Infusionen 01:04:30 Spermidin 01:06:30 Blutplasmaaustausch 01:11:30 Zukunftsausblick 01:13:10 Abschließende Worte Instagram: https://www.instagram.com/med.alessandro/ https://www.youtube-nocookie.com/embed/GsHEJwgG6k4 4552 2025-04-30T03:00:30.000Z 2026-10-22T17:11:30.669Z https://longevityharbor.com/de/watch/GsHEJwgG6k4 Altersforscher klärt auf: Können wir unsere biologische Uhr zurückdrehen? | Prof. Björn Schumacher https://i.ytimg.com/vi/GsHEJwgG6k4/hqdefault.jpg In dieser Episode spreche ich mit Prof. Björn Schumacher, Direktor des Instituts für Genomstabilität bei Alterung und Erkrankung am CECAD-Forschungszentrum der Universität Köln. Unser Thema: die Biologie des Alterns. Was passiert in unserem Körper, wenn wir älter werden – und was können wir aktiv tun, um diesen Prozess positiv zu beeinflussen? Neben bewährten Lebensstilfaktoren rücken zunehmend auch gezielte Interventionen wie Medikamente oder Nahrungsergänzungsmittel in den Fokus der Forschung. In dieser Folge erfährst du: ✅ Was beim Altern auf zellulärer Ebene wirklich passiert 💊 Welche Medikamente und Supplements gerade erforscht werden ⚠️ Warum manche „Anti-Aging“-Strategien mehr schaden als nutzen 🏋️‍♂️ Welche Rolle Lebensstil, Ernährung und Bewegung weiterhin spielen 🔬 Wie nah wir tatsächlich an einer gezielten „Verlangsamung des Alterns“ sind Modern Medicine lebt von der Unterstützung der Menschen, die diesen Podcast hören. Wenn du dazu beitragen willst, dass es weitergeht, und zusätzlich exklusive Bonusinhalte erhalten möchtest, kannst du mich hier supporten: ⁠⁠⁠⁠https://steady.page/modern-medicine⁠⁠⁠⁠ Kapitel: 00:00:00 Intro 00:00:50 Die Biologie des Alterns 00:05:30 Programmierter Prozess oder zufällige Schäden? 00:07:30 Genetik vs Umweltfaktoren 00:09:30 Faktoren, die das Altern beeinflussen 00:11:30 Kalorische Restriktion 00:15:00 Übergewicht 00:17:15 Chronologisches vs biologisches Alter 00:18:00 Können wir Altern messen? 00:20:30 Altersuhren: Epigenetische Muster 00:25:00 Alterstest für Verbraucher 00:30:00 Zukünftige Altersuhren 00:33:00 Medikamente gegen das Altern 00:33:30 Rapamycin 00:38:00 Mausstudien vs humane Studien 00:40:00 GLP-1 Agonisten (Abnehmsprritzen) 00:45:00 Metformin 00:50:00 Die wichtige Rolle der Muskelmasse 00:54:00 Resveratrol 00:57:30 NAD-Booster (NR, NMN) 01:00:00 NAD-Infusionen 01:04:30 Spermidin 01:06:30 Blutplasmaaustausch 01:11:30 Zukunftsausblick 01:13:10 Abschließende Worte Instagram: https://www.instagram.com/med.alessandro/ https://www.youtube-nocookie.com/embed/GsHEJwgG6k4 4552 2025-04-30T03:00:30.000Z 2026-10-22T17:11:30.669Z https://longevityharbor.com/en/watch/GsflY4ZA_S4 Video description: cellular senescence, biomarkers and senotherapeutics under study https://i.ytimg.com/vi/GsflY4ZA_S4/hqdefault.jpg The description says the video covers senescence, senescence-associated biomarkers and senolytic and senomorphic strategies being investigated; it stresses that no established anti-ageing treatment exists. https://www.youtube-nocookie.com/embed/GsflY4ZA_S4 549 2026-09-01T16:15:43.000Z 2026-10-22T22:35:32.927Z https://longevityharbor.com/de/watch/GsflY4ZA_S4 Videobeschreibung: Zelluläre Seneszenz, Biomarker und Senotherapeutika in Forschung https://i.ytimg.com/vi/GsflY4ZA_S4/hqdefault.jpg Laut Beschreibung behandelt das Video Seneszenz, seneszenzassoziierte Biomarker sowie untersuchte senolytische und senomorphe Strategien; ein etabliertes Anti-Aging-Mittel gebe es nicht. https://www.youtube-nocookie.com/embed/GsflY4ZA_S4 549 2026-09-01T16:15:43.000Z 2026-10-22T22:35:32.927Z https://longevityharbor.com/en/watch/GttgOce3I7k NMN and NR raise NAD markers; human health benefits unproven https://i.ytimg.com/vi/GttgOce3I7k/hqdefault.jpg The description says trials show NMN and NR can raise NAD-related biomarkers, but whether they rejuvenate healthy people, prevent age-related disease or extend human life remains unproven. https://www.youtube-nocookie.com/embed/GttgOce3I7k 562 2026-09-17T20:45:17.000Z 2026-10-22T22:05:37.778Z https://longevityharbor.com/de/watch/GttgOce3I7k NMN und NR erhöhen NAD-Marker; gesundheitlicher Nutzen beim Menschen unbelegt https://i.ytimg.com/vi/GttgOce3I7k/hqdefault.jpg Laut Beschreibung zeigen Studien, dass NMN und NR NAD-bezogene Biomarker erhöhen können; ob sie gesunde Menschen verjüngen, altersbezogene Krankheiten verhindern oder das menschliche Leben verlängern, bleibt jedoch unbelegt. https://www.youtube-nocookie.com/embed/GttgOce3I7k 562 2026-09-17T20:45:17.000Z 2026-10-22T22:05:37.778Z https://longevityharbor.com/en/watch/GwtJavuKbTM Ayurvedische Ernährung: Geheimnisse für gesundes Altern https://i.ytimg.com/vi/GwtJavuKbTM/hqdefault.jpg Ayurvedische Ernährung: Geheimnisse für gesundes Altern https://www.youtube-nocookie.com/embed/GwtJavuKbTM 1305 2024-08-24T17:22:00.000Z 2026-10-22T18:43:10.857Z https://longevityharbor.com/de/watch/GwtJavuKbTM Ayurvedische Ernährung: Geheimnisse für gesundes Altern https://i.ytimg.com/vi/GwtJavuKbTM/hqdefault.jpg Ayurvedische Ernährung: Geheimnisse für gesundes Altern https://www.youtube-nocookie.com/embed/GwtJavuKbTM 1305 2024-08-24T17:22:00.000Z 2026-10-22T18:43:10.857Z https://longevityharbor.com/en/watch/GzD-XSzfyrA Resveratrol and aging: what a podcast clip's description says https://i.ytimg.com/vi/GzD-XSzfyrA/hqdefault.jpg The description says resveratrol, a compound in foods such as grapes, has been studied for possible effects on aging, longevity, cellular health and metabolism, but it gives no study results. https://www.youtube-nocookie.com/embed/GzD-XSzfyrA 94 2026-09-28T11:44:26.000Z 2026-10-22T21:40:37.171Z https://longevityharbor.com/de/watch/GzD-XSzfyrA Resveratrol und Altern: Was die Beschreibung eines Podcast-Clips sagt https://i.ytimg.com/vi/GzD-XSzfyrA/hqdefault.jpg Die Beschreibung nennt Resveratrol, eine Verbindung in Lebensmitteln wie Weintrauben, die auf mögliche Effekte auf Altern, Langlebigkeit, Zellgesundheit und Stoffwechsel untersucht wurde; Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/GzD-XSzfyrA 94 2026-09-28T11:44:26.000Z 2026-10-22T21:40:37.171Z https://longevityharbor.com/en/watch/H1Px8kQnxYg Biological age: blood, DNA and longevity tests explained https://i.ytimg.com/vi/H1Px8kQnxYg/hqdefault.jpg The creator describes three ways to estimate biological age — blood-based calculators, epigenetic DNA testing and broader longevity services — and says results from different methods should not be compared automatically. https://www.youtube-nocookie.com/embed/H1Px8kQnxYg 431 2026-08-18T23:55:07.000Z 2026-10-22T22:56:10.138Z https://longevityharbor.com/de/watch/H1Px8kQnxYg Biologisches Alter: Blut-, DNA- und Longevity-Tests erklärt https://i.ytimg.com/vi/H1Px8kQnxYg/hqdefault.jpg Der Ersteller beschreibt drei Wege zur Schätzung des biologischen Alters – Blutrechner, epigenetische DNA-Tests und breitere Longevity-Dienste – und sagt, Ergebnisse verschiedener Methoden sollten nicht automatisch verglichen werden. https://www.youtube-nocookie.com/embed/H1Px8kQnxYg 431 2026-08-18T23:55:07.000Z 2026-10-22T22:56:10.138Z https://longevityharbor.com/en/watch/H7Qw1v0aXNQ Circadian Rhythm and Chrononutrition https://i.ytimg.com/vi/H7Qw1v0aXNQ/hqdefault.jpg Circadian Rhythms & Food Timing | Mimansa Mastermind – Session 1 What if the time you eat dinner tonight could literally reprogram the clock genes in your fat cells by tomorrow morning? In this session, we explore how genes, light, and meals interact to shape your health, energy, and longevity. What you’ll learn: – Why eating at the right times reduces inflammation and improves sleep – How your genes and microbiome respond to light-dark cycles – Practical strategies for meal timing to support hormones, metabolism, and healthy aging – A simple 24-hour rhythm plan (sleep, meals, movement) you can start using today This talk blends Nobel Prize-winning circadian science with actionable strategies you can apply right now for better health and longevity. ✨ Join the Kosha Cleanse – 21 Day Rhythm Reset (begins Oct 6, 2025) Led by Dr. Mima MD priced at $333 USD → Confirm your registration by email: hello@mimansa.ai → Connect with our private KOSHA community on WhatsApp 📌 Stay connected: Subscribe for more sessions on circadian biology, genomics, and longevity. 👍 Like this video if you found it helpful. 🔔 Turn on notifications so you don’t miss upcoming Mastermind talks. https://www.youtube-nocookie.com/embed/H7Qw1v0aXNQ 2417 2025-10-03T04:20:16.000Z 2026-10-22T18:54:02.217Z https://longevityharbor.com/de/watch/H7Qw1v0aXNQ Circadian Rhythm and Chrononutrition https://i.ytimg.com/vi/H7Qw1v0aXNQ/hqdefault.jpg Circadian Rhythms & Food Timing | Mimansa Mastermind – Session 1 What if the time you eat dinner tonight could literally reprogram the clock genes in your fat cells by tomorrow morning? In this session, we explore how genes, light, and meals interact to shape your health, energy, and longevity. What you’ll learn: – Why eating at the right times reduces inflammation and improves sleep – How your genes and microbiome respond to light-dark cycles – Practical strategies for meal timing to support hormones, metabolism, and healthy aging – A simple 24-hour rhythm plan (sleep, meals, movement) you can start using today This talk blends Nobel Prize-winning circadian science with actionable strategies you can apply right now for better health and longevity. ✨ Join the Kosha Cleanse – 21 Day Rhythm Reset (begins Oct 6, 2025) Led by Dr. Mima MD priced at $333 USD → Confirm your registration by email: hello@mimansa.ai → Connect with our private KOSHA community on WhatsApp 📌 Stay connected: Subscribe for more sessions on circadian biology, genomics, and longevity. 👍 Like this video if you found it helpful. 🔔 Turn on notifications so you don’t miss upcoming Mastermind talks. https://www.youtube-nocookie.com/embed/H7Qw1v0aXNQ 2417 2025-10-03T04:20:16.000Z 2026-10-22T18:54:02.217Z https://longevityharbor.com/en/watch/H7dL-eKQpoM Seneszente Zellen – Experte Prof. Schmitt erklärt, wie ihre Bekämpfung Sinn machen könnte https://i.ytimg.com/vi/H7dL-eKQpoM/hqdefault.jpg In diesem Podcast spreche ich mit Prof. Dr. Clemens Schmitt, Professor für Hämatologie und Onkologie und leitender Forscher an der Charité Universitätsmedizin. Prof. Schmitt ist leitender Forscher am Max-Planck Delbrück-Zentrum für molekulare Medizin, dazu Direktor an der Uniklinik Linz und überhaupt international anerkannter Experte auch und besonders in Sachen zelluläre Seneszenz. Professor Clemens Schmidt erforscht mit seinem Team, wie und welche Senolytika beim Kampf gegen seneszente Zellen wirken könnten. In dieser Folge behandeln wir unter anderem folgende Fragen: - Was sind seneszente Zellen, und welche Rolle spielen sie im Alterungsprozess? - Inwiefern sind seneszente Zellen verantwortlich für Alterskrankheiten wie Osteoarthritis, Fibrosen, Diabetes und neurodegenerative Erkrankungen wie Alzheimer? - Wie beeinflusst der von seneszenten Zellen ausgeschüttete seneszenz-assoziierte sekretorische Phänotyp (SASP) den Alterungsprozess und die Entstehung von altersbedingten Entzündungen? - Wie führt eine Chemotherapie bei jungen Menschen zu einer vermehrten Bildung von seneszenten Zellen, und welche langfristigen Auswirkungen hat dies auf das Altern? - Was sind Senolytika, und wie wirken Substanzen wie Dasatinib, Quercetin und Fisetin bei der Eliminierung seneszenter Zellen? - Welche ersten klinischen Erfolge wurden bei der Anwendung von Senolytika erzielt, und bei welchen Alterskrankheiten zeigen sie bereits Wirkung? Weitere Informationen zu Prof. Schmitt findest du hier: https://www.bsio-cancerschool.de/bsio-faculty Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder Youtube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundhe https://www.youtube-nocookie.com/embed/H7dL-eKQpoM 3099 2024-10-25T04:00:06.000Z 2026-10-22T18:43:12.553Z https://longevityharbor.com/de/watch/H7dL-eKQpoM Seneszente Zellen – Experte Prof. Schmitt erklärt, wie ihre Bekämpfung Sinn machen könnte https://i.ytimg.com/vi/H7dL-eKQpoM/hqdefault.jpg In diesem Podcast spreche ich mit Prof. Dr. Clemens Schmitt, Professor für Hämatologie und Onkologie und leitender Forscher an der Charité Universitätsmedizin. Prof. Schmitt ist leitender Forscher am Max-Planck Delbrück-Zentrum für molekulare Medizin, dazu Direktor an der Uniklinik Linz und überhaupt international anerkannter Experte auch und besonders in Sachen zelluläre Seneszenz. Professor Clemens Schmidt erforscht mit seinem Team, wie und welche Senolytika beim Kampf gegen seneszente Zellen wirken könnten. In dieser Folge behandeln wir unter anderem folgende Fragen: - Was sind seneszente Zellen, und welche Rolle spielen sie im Alterungsprozess? - Inwiefern sind seneszente Zellen verantwortlich für Alterskrankheiten wie Osteoarthritis, Fibrosen, Diabetes und neurodegenerative Erkrankungen wie Alzheimer? - Wie beeinflusst der von seneszenten Zellen ausgeschüttete seneszenz-assoziierte sekretorische Phänotyp (SASP) den Alterungsprozess und die Entstehung von altersbedingten Entzündungen? - Wie führt eine Chemotherapie bei jungen Menschen zu einer vermehrten Bildung von seneszenten Zellen, und welche langfristigen Auswirkungen hat dies auf das Altern? - Was sind Senolytika, und wie wirken Substanzen wie Dasatinib, Quercetin und Fisetin bei der Eliminierung seneszenter Zellen? - Welche ersten klinischen Erfolge wurden bei der Anwendung von Senolytika erzielt, und bei welchen Alterskrankheiten zeigen sie bereits Wirkung? Weitere Informationen zu Prof. Schmitt findest du hier: https://www.bsio-cancerschool.de/bsio-faculty Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder Youtube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundhe https://www.youtube-nocookie.com/embed/H7dL-eKQpoM 3099 2024-10-25T04:00:06.000Z 2026-10-22T18:43:12.553Z https://longevityharbor.com/en/watch/HAL_N9D3lUc Lieber NEMs oder gesunde Ernährung? Ärztin erklärt https://i.ytimg.com/vi/HAL_N9D3lUc/hqdefault.jpg #frauengesundheit #gesundeernährung #nahrungsergänzungsmittel #wechseljahre #nährstoffe https://www.youtube-nocookie.com/embed/HAL_N9D3lUc 91 2026-01-25T07:45:04.000Z 2026-10-22T19:04:43.977Z https://longevityharbor.com/de/watch/HAL_N9D3lUc Lieber NEMs oder gesunde Ernährung? Ärztin erklärt https://i.ytimg.com/vi/HAL_N9D3lUc/hqdefault.jpg #frauengesundheit #gesundeernährung #nahrungsergänzungsmittel #wechseljahre #nährstoffe https://www.youtube-nocookie.com/embed/HAL_N9D3lUc 91 2026-01-25T07:45:04.000Z 2026-10-22T19:04:43.977Z https://longevityharbor.com/en/watch/HEgwqpf1bLA AI Said You Need These 5 Exercises for LIFE (Reverse Aging) https://i.ytimg.com/vi/HEgwqpf1bLA/hqdefault.jpg Build muscle, burn fat, improve posture, boost longevity, and fix joint pain — with just 5 exercises. This AI full-body workout works for men and women of all ages, whether you're in your 20s or over 50, in the USA, Canada, UK, Australia, or anywhere in the world. No gym required. No BS. Just raw functional strength that protects your body for life. These 5 movements were ranked by AI after analyzing thousands of studies. Why? Because they do more than just build muscle…they improve balance, strengthen your spine, increase mobility, and even predict how long you’ll live. In this video, you’ll discover: • A simple balance test that predicts how long you'll live • The grip strength trick that fixes posture and lung capacity • A full-body mobility test used by elite coaches • The real-world “carry test” for functional strength • The 2-minute REHIT sprint protocol that burns fat for hours Plus: the only 20-minute daily routine you need to stay strong, pain-free, and biologically younger than 99% of people. 🎁 BONUS: Get our guide: "Exercises You Must Avoid at All Costs" — backed by injury data and with safe replacements. 👉 https://www.eabstrong.com/eBook 📬 Subscribe to our newsletter for weekly anti-aging workouts, muscle-building tips, and fat loss protocols: 👉 https://evolveandbuild.beehiiv.com/subscribe Follow us on Social Media: Instagram: https://www.instagram.com/evolveandbuild/ TikTok: https://www.tiktok.com/@evolveandbuild YouTube: https://www.youtube.com/channel/UCDRFMhmLch_ebPOOx97EW0w Would you like to know more tips for fat loss, muscle building, higher testosterone, etc..? Sign up for our newsletter where we share the best tips for free: https://evolveandbuild.beehiiv.com/subscribe Timestamps: 0:00 10-Second Test to See How Long You’ll Live 1:10 Can You Hang for 30 Seconds? Here's Why 2:10 Most Underrated Exercise In The World 3:30 How To Always Stay Strong No Matter Age 4:40 2-Minute Exercise That Burns Fat for Hours + BONUS #buildmuscle #workout #exercises #ai #chatgpt https://www.youtube-nocookie.com/embed/HEgwqpf1bLA 413 2025-08-24T16:08:56.000Z 2026-10-22T18:32:08.334Z https://longevityharbor.com/de/watch/HEgwqpf1bLA AI Said You Need These 5 Exercises for LIFE (Reverse Aging) https://i.ytimg.com/vi/HEgwqpf1bLA/hqdefault.jpg Build muscle, burn fat, improve posture, boost longevity, and fix joint pain — with just 5 exercises. This AI full-body workout works for men and women of all ages, whether you're in your 20s or over 50, in the USA, Canada, UK, Australia, or anywhere in the world. No gym required. No BS. Just raw functional strength that protects your body for life. These 5 movements were ranked by AI after analyzing thousands of studies. Why? Because they do more than just build muscle…they improve balance, strengthen your spine, increase mobility, and even predict how long you’ll live. In this video, you’ll discover: • A simple balance test that predicts how long you'll live • The grip strength trick that fixes posture and lung capacity • A full-body mobility test used by elite coaches • The real-world “carry test” for functional strength • The 2-minute REHIT sprint protocol that burns fat for hours Plus: the only 20-minute daily routine you need to stay strong, pain-free, and biologically younger than 99% of people. 🎁 BONUS: Get our guide: "Exercises You Must Avoid at All Costs" — backed by injury data and with safe replacements. 👉 https://www.eabstrong.com/eBook 📬 Subscribe to our newsletter for weekly anti-aging workouts, muscle-building tips, and fat loss protocols: 👉 https://evolveandbuild.beehiiv.com/subscribe Follow us on Social Media: Instagram: https://www.instagram.com/evolveandbuild/ TikTok: https://www.tiktok.com/@evolveandbuild YouTube: https://www.youtube.com/channel/UCDRFMhmLch_ebPOOx97EW0w Would you like to know more tips for fat loss, muscle building, higher testosterone, etc..? Sign up for our newsletter where we share the best tips for free: https://evolveandbuild.beehiiv.com/subscribe Timestamps: 0:00 10-Second Test to See How Long You’ll Live 1:10 Can You Hang for 30 Seconds? Here's Why 2:10 Most Underrated Exercise In The World 3:30 How To Always Stay Strong No Matter Age 4:40 2-Minute Exercise That Burns Fat for Hours + BONUS #buildmuscle #workout #exercises #ai #chatgpt https://www.youtube-nocookie.com/embed/HEgwqpf1bLA 413 2025-08-24T16:08:56.000Z 2026-10-22T18:32:08.334Z https://longevityharbor.com/en/watch/HFVdBN1M02s Podcast description: rapamycin, mTOR and aging claims, with hype warnings https://i.ytimg.com/vi/HFVdBN1M02s/hqdefault.jpg The description says the episode covers how rapamycin inhibits mTOR, links between lower mTOR and slower biological aging in animals, and why mouse data are hard to translate to humans. It also announces discussion of the Dog Aging Project and the TRIAD rapamycin trial, plus warnings about longevity hype. https://www.youtube-nocookie.com/embed/HFVdBN1M02s 3384 2025-12-25T15:00:07.000Z 2026-10-23T03:09:50.452Z https://longevityharbor.com/de/watch/HFVdBN1M02s Podcast-Beschreibung: Rapamycin, mTOR und Alternsaussagen mit Warnung vor Hype https://i.ytimg.com/vi/HFVdBN1M02s/hqdefault.jpg Laut Beschreibung behandelt die Folge, wie Rapamycin mTOR hemmt, Zusammenhänge zwischen gedrosseltem mTOR und langsamerem biologischem Altern bei Tieren und die Schwierigkeit, Mausdaten auf Menschen zu übertragen. Angekündigt werden zudem das Dog Aging Project und die Rapamycin-Studie TRIAD sowie Warnungen vor Hype im Longevity-Bereich. https://www.youtube-nocookie.com/embed/HFVdBN1M02s 3384 2025-12-25T15:00:07.000Z 2026-10-23T03:09:50.452Z https://longevityharbor.com/en/watch/HInfiw80NB8 How Aging Works: New Biomarker Discovery Could Reverse Aging! https://i.ytimg.com/vi/HInfiw80NB8/hqdefault.jpg How Aging Works has been a mystery for decades, but scientists have just discovered a key biomarker that could change everything! Researchers at the Mayo Clinic have identified IL-23R as a crucial indicator of cellular senescence, the process where old cells stop dividing but refuse to die. This discovery could lead to groundbreaking anti-aging treatments! Senolytic therapies, which clear out these "zombie" cells, have been shown to reverse aging effects by lowering IL-23R levels. Understanding How Aging Works at the cellular level brings us closer to preventing age-related diseases and even extending lifespan. Watch now to learn How Aging Works and how this discovery could revolutionize longevity science! Subscribe: https://www.youtube.com/@ScientificResearchVideos2026?sub_confirmation=1 Disclosure: This video includes an AI-generated voiceover created for narration purposes. All information presented is based on publicly available sources and is intended for educational and informational use. https://www.youtube-nocookie.com/embed/HInfiw80NB8 231 2025-03-02T13:00:21.000Z 2026-10-22T19:43:47.780Z https://longevityharbor.com/de/watch/HInfiw80NB8 How Aging Works: New Biomarker Discovery Could Reverse Aging! https://i.ytimg.com/vi/HInfiw80NB8/hqdefault.jpg How Aging Works has been a mystery for decades, but scientists have just discovered a key biomarker that could change everything! Researchers at the Mayo Clinic have identified IL-23R as a crucial indicator of cellular senescence, the process where old cells stop dividing but refuse to die. This discovery could lead to groundbreaking anti-aging treatments! Senolytic therapies, which clear out these "zombie" cells, have been shown to reverse aging effects by lowering IL-23R levels. Understanding How Aging Works at the cellular level brings us closer to preventing age-related diseases and even extending lifespan. Watch now to learn How Aging Works and how this discovery could revolutionize longevity science! Subscribe: https://www.youtube.com/@ScientificResearchVideos2026?sub_confirmation=1 Disclosure: This video includes an AI-generated voiceover created for narration purposes. All information presented is based on publicly available sources and is intended for educational and informational use. https://www.youtube-nocookie.com/embed/HInfiw80NB8 231 2025-03-02T13:00:21.000Z 2026-10-22T19:43:47.780Z https://longevityharbor.com/en/watch/HNR2DAiVSd0 Can Biological Age Go Backwards? What Epigenetic Clocks Can and Cannot Tell Us https://i.ytimg.com/vi/HNR2DAiVSd0/hqdefault.jpg The video description explains that biological aging can be estimated with molecular markers such as DNA methylation, and that some biological clocks change after lifestyle, dietary or medical interventions. But a younger score does not mean the whole body is younger or that you will live longer. https://www.youtube-nocookie.com/embed/HNR2DAiVSd0 262 2026-10-20T09:00:49.000Z 2026-10-22T19:49:50.770Z https://longevityharbor.com/de/watch/HNR2DAiVSd0 Kann biologisches Alter rückwärts gehen? Was epigenetische Uhren zeigen können – und was nicht https://i.ytimg.com/vi/HNR2DAiVSd0/hqdefault.jpg Die Videobeschreibung erklärt, dass sich biologisches Altern mit molekularen Markern wie DNA-Methylierung schätzen lässt und dass sich manche biologischen Uhren nach Änderungen von Lebensstil, Ernährung oder medizinischen Eingriffen verändern. Ein jüngerer Wert bedeutet aber nicht, dass der ganze Körper jünger ist oder dass man länger lebt. https://www.youtube-nocookie.com/embed/HNR2DAiVSd0 262 2026-10-20T09:00:49.000Z 2026-10-22T19:49:50.770Z https://longevityharbor.com/en/watch/HR_L6-t5imY Video description: muscles produce myokines said to support metabolism, immunity and recovery https://i.ytimg.com/vi/HR_L6-t5imY/hqdefault.jpg According to the video description, muscles produce messenger substances called myokines, and regular movement plus targeted strength training is said to strengthen muscles, promote myokine production and support heart, metabolism and immune defences. https://www.youtube-nocookie.com/embed/HR_L6-t5imY 112 2026-03-25T09:00:21.000Z 2026-10-23T01:52:26.539Z https://longevityharbor.com/de/watch/HR_L6-t5imY Videobeschreibung: Muskeln bilden Myokine, die laut Beschreibung Stoffwechsel, Immunsystem und Regen https://i.ytimg.com/vi/HR_L6-t5imY/hqdefault.jpg Laut der Videobeschreibung bilden Muskeln Botenstoffe namens Myokine; regelmäßige Bewegung und gezieltes Krafttraining sollen die Muskeln stärken, die Myokin-Produktion fördern und Herz, Stoffwechsel und Abwehrkräfte unterstützen. https://www.youtube-nocookie.com/embed/HR_L6-t5imY 112 2026-03-25T09:00:21.000Z 2026-10-23T01:52:26.539Z https://longevityharbor.com/en/watch/HS9lIypQRA4 Die 12 Merkmale des Alterns (Hallmarks of Aging) https://i.ytimg.com/vi/HS9lIypQRA4/hqdefault.jpg In dieser Episode der Longevity News geht es um die 12 Merkmale des Alterns, darunter Stammzellen, Mitochondrien, Epigenetik, Genom, Dysbiose und chronische Entzündungen und mehr. Sebastian erläutert, wie diese Merkmale das biologische Altern beeinflussen und wie man darauf einwirken kann, um das biologische Alter zu verjüngen. Dabei werden die primären, die antagonistischen und die integrativen Merkmale sowie deren Auswirkungen auf den Alterungsprozess beleuchtet. Es wird auch aufgezeigt, wie man positiv auf das Altern einwirken kann und welche Maßnahmen zur Verjüngung und Unterstützung des Körpers ergriffen werden können. Ausbildung zum Longevity oder Epigenetic Coach: - kostenloser Beratungstermin: https://calendly.com/inex-marina/kostenloses-erstgespraech?month=2024-02 - Ausbildungsübersicht INEX Academy: https://www.inex-health.com/education Zeitstempel und Themen: 00:00 Die 12 Merkmale des Alterns: Ein umfassender Überblick 03:06 Einfluss der 12 Merkmale des Alterns auf das biologische Altern 08:22 Strategien zur Verjüngung des biologischen Alters 21:38 Primäre und antagonistische Merkmale des Alterns: Auswirkungen auf den Alterungsprozess 22:07 Maßnahmen zur Verjüngung und Unterstützung des Körpers Links: - Ausbildung zum Longevity Coach:https://www.inex-health.com/longevity-coach - mein kostenloses 22-seitiges Longevity Protokoll: https://www.inex-health.com/longevity-news - Hallmaks of Aging: https://www.cell.com/cell/fulltext/S0092-8674(22)01377-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867422013770%3Fshowall%3Dtrue - Genomische Stabilität und DNA Reparatur mit Dr. Schumacher: - Epigenetischer Informationsverlust: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166133/ - Telomerabrieb: https://ar.iiarjournals.org/content/anticanres/25/4/3011.full.pdf - Verlust der Proteostase: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101847/#:~:text=Aging%20cells%20accumulate%20damaged%20and,such%20as%20Alzheimer's%20and%20Huntington's. - Makroautophagy: https: https://www.youtube-nocookie.com/embed/HS9lIypQRA4 2070 2024-05-29T15:52:30.000Z 2026-10-22T17:43:39.274Z https://longevityharbor.com/de/watch/HS9lIypQRA4 Die 12 Merkmale des Alterns (Hallmarks of Aging) https://i.ytimg.com/vi/HS9lIypQRA4/hqdefault.jpg In dieser Episode der Longevity News geht es um die 12 Merkmale des Alterns, darunter Stammzellen, Mitochondrien, Epigenetik, Genom, Dysbiose und chronische Entzündungen und mehr. Sebastian erläutert, wie diese Merkmale das biologische Altern beeinflussen und wie man darauf einwirken kann, um das biologische Alter zu verjüngen. Dabei werden die primären, die antagonistischen und die integrativen Merkmale sowie deren Auswirkungen auf den Alterungsprozess beleuchtet. Es wird auch aufgezeigt, wie man positiv auf das Altern einwirken kann und welche Maßnahmen zur Verjüngung und Unterstützung des Körpers ergriffen werden können. Ausbildung zum Longevity oder Epigenetic Coach: - kostenloser Beratungstermin: https://calendly.com/inex-marina/kostenloses-erstgespraech?month=2024-02 - Ausbildungsübersicht INEX Academy: https://www.inex-health.com/education Zeitstempel und Themen: 00:00 Die 12 Merkmale des Alterns: Ein umfassender Überblick 03:06 Einfluss der 12 Merkmale des Alterns auf das biologische Altern 08:22 Strategien zur Verjüngung des biologischen Alters 21:38 Primäre und antagonistische Merkmale des Alterns: Auswirkungen auf den Alterungsprozess 22:07 Maßnahmen zur Verjüngung und Unterstützung des Körpers Links: - Ausbildung zum Longevity Coach:https://www.inex-health.com/longevity-coach - mein kostenloses 22-seitiges Longevity Protokoll: https://www.inex-health.com/longevity-news - Hallmaks of Aging: https://www.cell.com/cell/fulltext/S0092-8674(22)01377-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867422013770%3Fshowall%3Dtrue - Genomische Stabilität und DNA Reparatur mit Dr. Schumacher: - Epigenetischer Informationsverlust: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166133/ - Telomerabrieb: https://ar.iiarjournals.org/content/anticanres/25/4/3011.full.pdf - Verlust der Proteostase: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101847/#:~:text=Aging%20cells%20accumulate%20damaged%20and,such%20as%20Alzheimer's%20and%20Huntington's. - Makroautophagy: https: https://www.youtube-nocookie.com/embed/HS9lIypQRA4 2070 2024-05-29T15:52:30.000Z 2026-10-22T17:43:39.274Z https://longevityharbor.com/en/watch/HU28xnhUfec The 9 Hallmarks of Aging Explained | How Scientists Target Longevity | GlobalRPh https://i.ytimg.com/vi/HU28xnhUfec/hqdefault.jpg The 9 Hallmarks of Aging Explained | How Scientists Target Longevity | GlobalRPh Breaking the Code: New Molecular Targets Reset the Hallmarks of Aging Can we truly reset the biological clock? In this in-depth lecture, we explore how cutting-edge molecular interventions—such as TERT reactivation, SIRT6-mediated DNA repair, senolytic therapies, and epigenetic reprogramming—are redefining aging as a modifiable biological process, rather than an unavoidable fate. You’ll learn how scientists are targeting the fundamental drivers of aging to extend healthspan, delay disease onset, and potentially reverse age-related functional decline. What You’ll Learn How telomerase (TERT) functions beyond telomere lengthening to regulate neurogenesis, inflammation, and cellular survival Molecular mechanisms behind telomere attrition, genomic instability, impaired DNA repair, and epigenetic drift How senolytic therapies eliminate p16INK4a-positive senescent cells to restore tissue function The role of mTOR inhibition and NAD+ boosting in improving proteostasis and mitochondrial performance How partial epigenetic reprogramming (OSK/Yamanaka factors) can reset cellular aging markers Translational implications for Alzheimer’s disease, cardiovascular disease, cancer, and metabolic disorders Who Should Watch Physicians, researchers, geriatricians, pharmacists, biomedical scientists, and healthcare professionals interested in longevity medicine, regenerative therapies, and translational aging research. Key Takeaway The future of aging medicine is shifting from symptom management to biological intervention—targeting core aging mechanisms to preserve function, resilience, and vitality. Future-forward. Evidence-based. Clinically relevant. 📺 Subscribe to GlobalRPh for more expert-led lectures on the frontiers of longevity science and biomedical innovation. #Longevity #AgingScience #HallmarksOfAging #AntiAgingResearch #Healthspan #Geroscience #Senolytics #Telomerase #Epigenetics #NADplus #mTOR #RegenerativeMedicine #LongevityMe https://www.youtube-nocookie.com/embed/HU28xnhUfec 1496 2025-07-29T23:21:49.000Z 2026-10-22T17:43:39.303Z https://longevityharbor.com/de/watch/HU28xnhUfec The 9 Hallmarks of Aging Explained | How Scientists Target Longevity | GlobalRPh https://i.ytimg.com/vi/HU28xnhUfec/hqdefault.jpg The 9 Hallmarks of Aging Explained | How Scientists Target Longevity | GlobalRPh Breaking the Code: New Molecular Targets Reset the Hallmarks of Aging Can we truly reset the biological clock? In this in-depth lecture, we explore how cutting-edge molecular interventions—such as TERT reactivation, SIRT6-mediated DNA repair, senolytic therapies, and epigenetic reprogramming—are redefining aging as a modifiable biological process, rather than an unavoidable fate. You’ll learn how scientists are targeting the fundamental drivers of aging to extend healthspan, delay disease onset, and potentially reverse age-related functional decline. What You’ll Learn How telomerase (TERT) functions beyond telomere lengthening to regulate neurogenesis, inflammation, and cellular survival Molecular mechanisms behind telomere attrition, genomic instability, impaired DNA repair, and epigenetic drift How senolytic therapies eliminate p16INK4a-positive senescent cells to restore tissue function The role of mTOR inhibition and NAD+ boosting in improving proteostasis and mitochondrial performance How partial epigenetic reprogramming (OSK/Yamanaka factors) can reset cellular aging markers Translational implications for Alzheimer’s disease, cardiovascular disease, cancer, and metabolic disorders Who Should Watch Physicians, researchers, geriatricians, pharmacists, biomedical scientists, and healthcare professionals interested in longevity medicine, regenerative therapies, and translational aging research. Key Takeaway The future of aging medicine is shifting from symptom management to biological intervention—targeting core aging mechanisms to preserve function, resilience, and vitality. Future-forward. Evidence-based. Clinically relevant. 📺 Subscribe to GlobalRPh for more expert-led lectures on the frontiers of longevity science and biomedical innovation. #Longevity #AgingScience #HallmarksOfAging #AntiAgingResearch #Healthspan #Geroscience #Senolytics #Telomerase #Epigenetics #NADplus #mTOR #RegenerativeMedicine #LongevityMe https://www.youtube-nocookie.com/embed/HU28xnhUfec 1496 2025-07-29T23:21:49.000Z 2026-10-22T17:43:39.303Z https://longevityharbor.com/en/watch/HWMI7Mpi1Mo Fasting: The Key to Longevity and Reversing Damage https://i.ytimg.com/vi/HWMI7Mpi1Mo/hqdefault.jpg Unlock a longer, healthier life through fasting. Discover how caloric restriction can optimize cellular metabolism, reverse damage from processed foods, and help you perform at your peak. The only known method to extend lifespan. #Fasting #Health #Longevity #Wellness #CellularHealth https://www.youtube-nocookie.com/embed/HWMI7Mpi1Mo 93 2026-02-21T23:04:24.000Z 2026-10-22T19:32:30.638Z https://longevityharbor.com/de/watch/HWMI7Mpi1Mo Fasting: The Key to Longevity and Reversing Damage https://i.ytimg.com/vi/HWMI7Mpi1Mo/hqdefault.jpg Unlock a longer, healthier life through fasting. Discover how caloric restriction can optimize cellular metabolism, reverse damage from processed foods, and help you perform at your peak. The only known method to extend lifespan. #Fasting #Health #Longevity #Wellness #CellularHealth https://www.youtube-nocookie.com/embed/HWMI7Mpi1Mo 93 2026-02-21T23:04:24.000Z 2026-10-22T19:32:30.638Z https://longevityharbor.com/en/watch/HZu7s52eOUc Book-launch episode on the hallmarks of aging with Red O'Laughlin https://i.ytimg.com/vi/HZu7s52eOUc/hqdefault.jpg The description presents a USA Global TV & Radio episode hosted by Red O'Laughlin, described as a longevity expert, for a book launch on the hallmarks of aging; the description gives no findings. https://www.youtube-nocookie.com/embed/HZu7s52eOUc 2684 2026-07-03T05:55:20.000Z 2026-10-22T23:41:29.114Z https://longevityharbor.com/de/watch/HZu7s52eOUc Buchvorstellungs-Episode zu den Hallmarks des Alterns mit Red O'Laughlin https://i.ytimg.com/vi/HZu7s52eOUc/hqdefault.jpg Die Beschreibung stellt eine Episode von USA Global TV & Radio vor, moderiert von Red O'Laughlin, bezeichnet als Longevity-Experte, zur Buchvorstellung über die Hallmarks des Alterns; die Beschreibung nennt keine Ergebnisse. https://www.youtube-nocookie.com/embed/HZu7s52eOUc 2684 2026-07-03T05:55:20.000Z 2026-10-22T23:41:29.114Z https://longevityharbor.com/en/watch/HbeGjwCw6vk Podcast discusses measuring aging and testing anti-aging drugs https://i.ytimg.com/vi/HbeGjwCw6vk/hqdefault.jpg In this podcast description, Dr. Nir Barzilai argues that medicine lacks a reliable way to tell whether an intervention changes the biology driving age-related disease, and discusses TAME, FAST and drugs studied as gerotherapeutics. https://www.youtube-nocookie.com/embed/HbeGjwCw6vk 3681 2026-09-10T10:00:12.000Z 2026-10-22T22:18:48.258Z https://longevityharbor.com/de/watch/HbeGjwCw6vk Podcast über das Messen des Alterns und die Prüfung von Anti-Aging-Medikamenten https://i.ytimg.com/vi/HbeGjwCw6vk/hqdefault.jpg In dieser Podcast-Beschreibung argumentiert Dr. Nir Barzilai, dass der Medizin ein verlässlicher Weg fehlt, um zu erkennen, ob eine Intervention die Biologie altersbezogener Krankheiten verändert; er spricht über TAME, FAST und als Gerotherapeutika untersuchte Medikamente. https://www.youtube-nocookie.com/embed/HbeGjwCw6vk 3681 2026-09-10T10:00:12.000Z 2026-10-22T22:18:48.258Z https://longevityharbor.com/en/watch/HbqCi_Ytfa0 Could GLP-1s Impact Aging and Cognitive Health? | Peter Attia, M.D. https://i.ytimg.com/vi/HbqCi_Ytfa0/hqdefault.jpg This clip is from episode #370 - AMA #76: Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — promising, proven, fuzzy, noise, or nonsense? In this clip, they discuss: - A New Class of Weight-Loss Drugs – GLP-1 medications stand out as the first that enable major weight loss without the lethal side effects of earlier drugs - GLP-1 and Longevity – Raises the question of whether these drugs could extend lifespan beyond their metabolic benefits - Emerging Cognitive Research – Mentions growing interest in GLP-1’s potential impact on brain health and cognitive performance -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users https://www.youtube-nocookie.com/embed/HbqCi_Ytfa0 118 2025-10-28T16:00:41.000Z 2026-10-22T20:11:50.484Z https://longevityharbor.com/de/watch/HbqCi_Ytfa0 Could GLP-1s Impact Aging and Cognitive Health? | Peter Attia, M.D. https://i.ytimg.com/vi/HbqCi_Ytfa0/hqdefault.jpg This clip is from episode #370 - AMA #76: Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — promising, proven, fuzzy, noise, or nonsense? In this clip, they discuss: - A New Class of Weight-Loss Drugs – GLP-1 medications stand out as the first that enable major weight loss without the lethal side effects of earlier drugs - GLP-1 and Longevity – Raises the question of whether these drugs could extend lifespan beyond their metabolic benefits - Emerging Cognitive Research – Mentions growing interest in GLP-1’s potential impact on brain health and cognitive performance -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users https://www.youtube-nocookie.com/embed/HbqCi_Ytfa0 118 2025-10-28T16:00:41.000Z 2026-10-22T20:11:50.484Z https://longevityharbor.com/en/watch/HehWSv1g0bE Hallmarks of aging: tidy textbook framework versus murky human medicine https://i.ytimg.com/vi/HehWSv1g0bE/hqdefault.jpg The description says the hallmarks of aging form a tidy textbook framework, but applying them in human clinical settings is murky, because causality versus correlation and thin human data remain unresolved. https://www.youtube-nocookie.com/embed/HehWSv1g0bE 171 2026-02-09T14:12:49.000Z 2026-10-23T02:36:09.713Z https://longevityharbor.com/de/watch/HehWSv1g0bE Hallmarks des Alterns: ordentliches Lehrbuch versus unklare Humanmedizin https://i.ytimg.com/vi/HehWSv1g0bE/hqdefault.jpg Laut Beschreibung bilden die Hallmarks des Alterns ein ordentliches Lehrbuchgerüst, doch die Anwendung im klinischen Alltag beim Menschen ist unklar, weil Kausalität gegenüber Korrelation und dünne Humandaten ungelöst bleiben. https://www.youtube-nocookie.com/embed/HehWSv1g0bE 171 2026-02-09T14:12:49.000Z 2026-10-23T02:36:09.713Z https://longevityharbor.com/en/watch/HhAs4l5rOEo Entzündungen im Körper ade? So geht antientzündliche Ernährung | Dr. Julia Fischer | ARD Gesund https://i.ytimg.com/vi/HhAs4l5rOEo/hqdefault.jpg Antientzündliche Ernährung ist gesund und wird bei Diabetes, Rheuma und anderen Erkrankungen empfohlen. In der Tat: Viele Krankheiten hängen mit Entzündungsprozessen im Körper zusammen. Wie geht antientzündliche Ernährung, was gehört auf den Teller und wie sinnvoll sind Supplements wie Omega-3-Kapseln? Dr. Julia Fischer hat fünf Tipps für dich. 00:00 - Antientzündliche Ernährung 00:55 - Was sind Entzündungen? 02:10 - Ungesunde Gewohnheiten 02:40 - Es gibt nicht den einen Weg 03:15 - Tipp Nr. 1 04:35 - Omega 6 entzündungsfördernd? 05:45 - Tipp Nr. 2 07:30 - Tipp Nr. 3 09:20 - Tipp Nr. 4 10:30 - Tipp Nr. 5 12:05 - Omega-3-Kapseln einnehmen? 12:30 - Schwarzkümmel-Öl? 13:10 - Ernährung ist das eine, aber ... Autor: Moritz Oliver Schröder Unsere Quellen: https://www.ncbi.nlm.nih.gov/books/NBK493173/ https://doi.org/10.1016/j.yrtph.2021.105088 https://pmc.ncbi.nlm.nih.gov/articles/PMC5633670/ https://doi.org/10.1515/abm-2020-0020 https://pubmed.ncbi.nlm.nih.gov/24925270/ https://pubmed.ncbi.nlm.nih.gov/27440261/ https://pubmed.ncbi.nlm.nih.gov/17655324/ https://pubmed.ncbi.nlm.nih.gov/35694805/ https://link.springer.com/article/10.1007/s11357-024-01262-5 https://pubmed.ncbi.nlm.nih.gov/29167102/ https://pubmed.ncbi.nlm.nih.gov/28826374/ https://www.mdpi.com/1420-3049/27/14/4400 https://pubs.acs.org/doi/10.1021/acs.jnatprod.5b00947 https://pmc.ncbi.nlm.nih.gov/articles/PMC8778110/ https://pubmed.ncbi.nlm.nih.gov/35042569/ https://www.dge.de/wissenschaft/referenzwerte/ballaststoffe/ https://www.dge.de/gesunde-ernaehrung/faq/ausgewaehlte-fragen-und-antworten-zu-ballaststoffen/ https://doi.org/10.1016/j.ajcnut.2023.11.010 Ein Film des NDR. Credit: NDR/Sebastian Reuter #NDR #entzündungshemmend #antioxidants ___________________________________________________ ARD GESUND mit Dr. Julia Fischer ist ein YouTube-Kanal von ARD GESUND https://www.youtube-nocookie.com/embed/HhAs4l5rOEo 875 2025-04-24T14:03:09.000Z 2026-10-22T19:43:44.134Z https://longevityharbor.com/de/watch/HhAs4l5rOEo Entzündungen im Körper ade? So geht antientzündliche Ernährung | Dr. Julia Fischer | ARD Gesund https://i.ytimg.com/vi/HhAs4l5rOEo/hqdefault.jpg Antientzündliche Ernährung ist gesund und wird bei Diabetes, Rheuma und anderen Erkrankungen empfohlen. In der Tat: Viele Krankheiten hängen mit Entzündungsprozessen im Körper zusammen. Wie geht antientzündliche Ernährung, was gehört auf den Teller und wie sinnvoll sind Supplements wie Omega-3-Kapseln? Dr. Julia Fischer hat fünf Tipps für dich. 00:00 - Antientzündliche Ernährung 00:55 - Was sind Entzündungen? 02:10 - Ungesunde Gewohnheiten 02:40 - Es gibt nicht den einen Weg 03:15 - Tipp Nr. 1 04:35 - Omega 6 entzündungsfördernd? 05:45 - Tipp Nr. 2 07:30 - Tipp Nr. 3 09:20 - Tipp Nr. 4 10:30 - Tipp Nr. 5 12:05 - Omega-3-Kapseln einnehmen? 12:30 - Schwarzkümmel-Öl? 13:10 - Ernährung ist das eine, aber ... Autor: Moritz Oliver Schröder Unsere Quellen: https://www.ncbi.nlm.nih.gov/books/NBK493173/ https://doi.org/10.1016/j.yrtph.2021.105088 https://pmc.ncbi.nlm.nih.gov/articles/PMC5633670/ https://doi.org/10.1515/abm-2020-0020 https://pubmed.ncbi.nlm.nih.gov/24925270/ https://pubmed.ncbi.nlm.nih.gov/27440261/ https://pubmed.ncbi.nlm.nih.gov/17655324/ https://pubmed.ncbi.nlm.nih.gov/35694805/ https://link.springer.com/article/10.1007/s11357-024-01262-5 https://pubmed.ncbi.nlm.nih.gov/29167102/ https://pubmed.ncbi.nlm.nih.gov/28826374/ https://www.mdpi.com/1420-3049/27/14/4400 https://pubs.acs.org/doi/10.1021/acs.jnatprod.5b00947 https://pmc.ncbi.nlm.nih.gov/articles/PMC8778110/ https://pubmed.ncbi.nlm.nih.gov/35042569/ https://www.dge.de/wissenschaft/referenzwerte/ballaststoffe/ https://www.dge.de/gesunde-ernaehrung/faq/ausgewaehlte-fragen-und-antworten-zu-ballaststoffen/ https://doi.org/10.1016/j.ajcnut.2023.11.010 Ein Film des NDR. Credit: NDR/Sebastian Reuter #NDR #entzündungshemmend #antioxidants ___________________________________________________ ARD GESUND mit Dr. Julia Fischer ist ein YouTube-Kanal von ARD GESUND https://www.youtube-nocookie.com/embed/HhAs4l5rOEo 875 2025-04-24T14:03:09.000Z 2026-10-22T19:43:44.134Z https://longevityharbor.com/en/watch/HnDN91RFSyI Circadian biologist Russell Foster on body clocks, chronotypes and shift work https://i.ytimg.com/vi/HnDN91RFSyI/hqdefault.jpg In this podcast description, circadian biologist Russell Foster explains internal clocks, light as the main daily time cue, biological lark-versus-owl chronotypes and what may help people readjust or work with their rhythm. https://www.youtube-nocookie.com/embed/HnDN91RFSyI 2926 2026-07-13T03:00:25.000Z 2026-10-22T23:35:04.153Z https://longevityharbor.com/de/watch/HnDN91RFSyI Chronobiologe Russell Foster über innere Uhren, Chronotypen und Schichtarbeit https://i.ytimg.com/vi/HnDN91RFSyI/hqdefault.jpg In dieser Podcast-Beschreibung erklärt der Chronobiologe Russell Foster innere Uhren, Licht als wichtigsten täglichen Zeitgeber, biologische Chronotypen als Lerche oder Eule und was Menschen helfen kann, ihren Rhythmus anzupassen oder mit ihm zu arbeiten. https://www.youtube-nocookie.com/embed/HnDN91RFSyI 2926 2026-07-13T03:00:25.000Z 2026-10-22T23:35:04.153Z https://longevityharbor.com/en/watch/HpiddWyX1mI Video description on epigenetics, lifestyle and biological age https://i.ytimg.com/vi/HpiddWyX1mI/hqdefault.jpg The description says the video explains DNA methylation and histone modifications, how lifestyle factors such as diet, sleep, stress and exercise influence gene activity, and how biological age might be lowered. These are creator claims; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/HpiddWyX1mI 384 2026-01-08T13:00:39.000Z 2026-10-23T02:57:01.154Z https://longevityharbor.com/de/watch/HpiddWyX1mI Videobeschreibung zu Epigenetik, Lebensstil und biologischem Alter https://i.ytimg.com/vi/HpiddWyX1mI/hqdefault.jpg Laut Beschreibung erklärt das Video DNA-Methylierung und Histonmodifikationen, wie Lebensstilfaktoren wie Ernährung, Schlaf, Stress und Bewegung die Genaktivität beeinflussen und wie sich das biologische Alter senken lassen könnte. Das sind Angaben des Erstellers; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/HpiddWyX1mI 384 2026-01-08T13:00:39.000Z 2026-10-23T02:57:01.154Z https://longevityharbor.com/en/watch/HqexdZAzd-s An Update on the Epigenetic Clock of Human Aging https://i.ytimg.com/vi/HqexdZAzd-s/hqdefault.jpg Watch as Dr. Steve Horvath, Dr. James P. Watson, and Dr. Keith Booher explore recent advances and discoveries surrounding the Epigenetic Aging Clock. This webinar dives into the cutting-edge research that is reshaping our understanding of aging and the potential for epigenetic biomarkers to track biological age. Learn more about Zymo Research's Epigenetic Age Analysis Service: https://www.zymoresearch.com/pages/dnage?utm_source=youtube&utm_medium=social-organic&utm_campaign=epigenetic-aging #Aging #EpigeneticAging #AgingClock #Biomarkers #Genomics #Epigenetics #ZymoResearch --------------------------------------------------------------------------------------------- Want to talk to a scientist? Contact us: https://www.zymoresearch.com/pages/contact?utm_source=youtube&utm_medium=social-organic&utm_campaign=contact Website: http://www.zymoresearch.com LinkedIn: https://www.linkedin.com/company/zymo-research-corp Instagram: https://instagram.com/zymo_research/ Twitter: https://twitter.com/zymoresearch Bluesky: https://bsky.app/profile/zymoresearch.bsky.social https://www.youtube-nocookie.com/embed/HqexdZAzd-s 9458 2020-04-10T01:41:44.000Z 2026-10-22T17:43:35.302Z https://longevityharbor.com/de/watch/HqexdZAzd-s An Update on the Epigenetic Clock of Human Aging https://i.ytimg.com/vi/HqexdZAzd-s/hqdefault.jpg Watch as Dr. Steve Horvath, Dr. James P. Watson, and Dr. Keith Booher explore recent advances and discoveries surrounding the Epigenetic Aging Clock. This webinar dives into the cutting-edge research that is reshaping our understanding of aging and the potential for epigenetic biomarkers to track biological age. Learn more about Zymo Research's Epigenetic Age Analysis Service: https://www.zymoresearch.com/pages/dnage?utm_source=youtube&utm_medium=social-organic&utm_campaign=epigenetic-aging #Aging #EpigeneticAging #AgingClock #Biomarkers #Genomics #Epigenetics #ZymoResearch --------------------------------------------------------------------------------------------- Want to talk to a scientist? Contact us: https://www.zymoresearch.com/pages/contact?utm_source=youtube&utm_medium=social-organic&utm_campaign=contact Website: http://www.zymoresearch.com LinkedIn: https://www.linkedin.com/company/zymo-research-corp Instagram: https://instagram.com/zymo_research/ Twitter: https://twitter.com/zymoresearch Bluesky: https://bsky.app/profile/zymoresearch.bsky.social https://www.youtube-nocookie.com/embed/HqexdZAzd-s 9458 2020-04-10T01:41:44.000Z 2026-10-22T17:43:35.302Z https://longevityharbor.com/en/watch/Hs7kHWcSZwU Video description on senescent cells, senolytics and biological aging https://i.ytimg.com/vi/Hs7kHWcSZwU/hqdefault.jpg The description presents senescent cells as damaged cells that accumulate and release inflammatory chemicals, and describes senolytics as an emerging research field asking whether removing such cells could partly improve the surrounding tissue environment. It states this is not immortality. https://www.youtube-nocookie.com/embed/Hs7kHWcSZwU 675 2026-05-20T04:48:49.000Z 2026-10-23T00:37:50.285Z https://longevityharbor.com/de/watch/Hs7kHWcSZwU Videobeschreibung zu seneszenten Zellen, Senolytika und biologischem Altern https://i.ytimg.com/vi/Hs7kHWcSZwU/hqdefault.jpg Die Beschreibung stellt seneszente Zellen als geschädigte Zellen dar, die sich ansammeln und entzündliche Stoffe freisetzen, und beschreibt Senolytika als aufkommendes Forschungsfeld mit der Frage, ob das Entfernen solcher Zellen die Umgebung im Gewebe teilweise verbessern könnte. Sie betont, dass dies keine Unsterblichkeit ist. https://www.youtube-nocookie.com/embed/Hs7kHWcSZwU 675 2026-05-20T04:48:49.000Z 2026-10-23T00:37:50.285Z https://longevityharbor.com/en/watch/HvfE-jGKmRA Video description: genetics, aging biology and longevity claims https://i.ytimg.com/vi/HvfE-jGKmRA/hqdefault.jpg The description says the episode reviews twin studies, centenarian genetics, hallmarks of aging, Blue Zones, calorie restriction, geroprotectors and social factors, and notes that genetics explains a smaller share than assumed. https://www.youtube-nocookie.com/embed/HvfE-jGKmRA 3115 2026-07-31T22:00:24.000Z 2026-10-22T23:16:27.726Z https://longevityharbor.com/de/watch/HvfE-jGKmRA Videobeschreibung: Genetik, Alternsbiologie und Langlebigkeitsaussagen https://i.ytimg.com/vi/HvfE-jGKmRA/hqdefault.jpg Laut Beschreibung behandelt die Episode Zwillingsstudien, Genetik von Hundertjährigen, Alternsmerkmale, Blue Zones, Kalorienrestriktion, Geroprotektoren und soziale Faktoren; Genetik erkläre einen kleineren Anteil als angenommen. https://www.youtube-nocookie.com/embed/HvfE-jGKmRA 3115 2026-07-31T22:00:24.000Z 2026-10-22T23:16:27.726Z https://longevityharbor.com/en/watch/I0Gg0_JcH5A Can Rapamycin Extend Your Life? https://i.ytimg.com/vi/I0Gg0_JcH5A/hqdefault.jpg Rapamycin: Unlocking Lifespan Secrets Join Dr. Nick Karr as he delves into the fascinating world of rapamycin, a drug with the potential to impact longevity and healthy aging. Discover the origins of rapamycin, its medical uses, and the research suggesting it could extend lifespan across multiple species. Learn about the dual nature of rapamycin's immunosuppressive properties and its possible benefits in enhancing immune function, cardiovascular health, cognition, cancer suppression, and more. Dr. Karr discusses the risks, myths, and the need for further research, providing a balanced view of rapamycin's potential as a powerful tool for aging and overall health. Like, subscribe, and share if you find this deep dive beneficial. 00:00 Introduction to Rapamycin 00:38 The Origins and Discovery of Rapamycin 02:33 Medical Uses and FDA Approvals 04:41 Rapamycin in Longevity Research 05:52 Mechanism of Action: mTOR and Autophagy 06:57 Health Benefits and Research Findings 14:07 Potential Side Effects and Risks 17:24 Debunking Myths and Misconceptions 21:24 Final Thoughts and Recommendations 23:30 Conclusion and Call to Action https://www.youtube-nocookie.com/embed/I0Gg0_JcH5A 1428 2025-03-11T18:00:20.000Z 2026-10-22T18:43:08.013Z https://longevityharbor.com/de/watch/I0Gg0_JcH5A Can Rapamycin Extend Your Life? https://i.ytimg.com/vi/I0Gg0_JcH5A/hqdefault.jpg Rapamycin: Unlocking Lifespan Secrets Join Dr. Nick Karr as he delves into the fascinating world of rapamycin, a drug with the potential to impact longevity and healthy aging. Discover the origins of rapamycin, its medical uses, and the research suggesting it could extend lifespan across multiple species. Learn about the dual nature of rapamycin's immunosuppressive properties and its possible benefits in enhancing immune function, cardiovascular health, cognition, cancer suppression, and more. Dr. Karr discusses the risks, myths, and the need for further research, providing a balanced view of rapamycin's potential as a powerful tool for aging and overall health. Like, subscribe, and share if you find this deep dive beneficial. 00:00 Introduction to Rapamycin 00:38 The Origins and Discovery of Rapamycin 02:33 Medical Uses and FDA Approvals 04:41 Rapamycin in Longevity Research 05:52 Mechanism of Action: mTOR and Autophagy 06:57 Health Benefits and Research Findings 14:07 Potential Side Effects and Risks 17:24 Debunking Myths and Misconceptions 21:24 Final Thoughts and Recommendations 23:30 Conclusion and Call to Action https://www.youtube-nocookie.com/embed/I0Gg0_JcH5A 1428 2025-03-11T18:00:20.000Z 2026-10-22T18:43:08.013Z https://longevityharbor.com/en/watch/I0_LndImjh0 Muskeln weg ab 60? 5 Bewegungen, die Ihren Körper sofort um 15 Jahre verjüngen! https://i.ytimg.com/vi/I0_LndImjh0/hqdefault.jpg Muskeln weg ab 60? 5 Bewegungen, die Ihren Körper sofort um 15 Jahre verjüngen! Stellen Sie sich vor, Sie könnten die Uhr einfach zurückdrehen. Was wäre, wenn nur 8 Wochen genügen, um sich körperlich 15 Jahre jünger zu fühlen? Ein erfahrener Chirurg bricht sein Schweigen und enthüllt die Wahrheit über den Muskelabbau im Alter. Entdecken Sie 5 spezifische, wissenschaftlich belegte Bewegungen, die Ihre schlafenden Stammzellen wecken und den Alterungsprozess stoppen – ganz ohne teure Medikamente oder Fitnessstudio. Diese Übungen sind Ihr Schlüssel zu neuer Kraft, Balance und Unabhängigkeit bis ins hohe Alter. Haftungsausschluss: Die in diesem Video bereitgestellten Inhalte dienen ausschließlich Informations- und Bildungszwecken. Sie stellen keinen medizinischen Rat dar und ersetzen keine professionelle Diagnose oder Behandlung durch einen Arzt. #AntiAging #GesundheitAb60 #FitnessFürSenioren #Langlebigkeit #Muskelaufbau #GesundAltern #BewegungHilft #Rückenschmerzen #SeniorenSport #Vitalität https://www.youtube-nocookie.com/embed/I0_LndImjh0 1266 2025-12-13T15:00:27.000Z 2026-10-22T18:32:07.469Z https://longevityharbor.com/de/watch/I0_LndImjh0 Muskeln weg ab 60? 5 Bewegungen, die Ihren Körper sofort um 15 Jahre verjüngen! https://i.ytimg.com/vi/I0_LndImjh0/hqdefault.jpg Muskeln weg ab 60? 5 Bewegungen, die Ihren Körper sofort um 15 Jahre verjüngen! Stellen Sie sich vor, Sie könnten die Uhr einfach zurückdrehen. Was wäre, wenn nur 8 Wochen genügen, um sich körperlich 15 Jahre jünger zu fühlen? Ein erfahrener Chirurg bricht sein Schweigen und enthüllt die Wahrheit über den Muskelabbau im Alter. Entdecken Sie 5 spezifische, wissenschaftlich belegte Bewegungen, die Ihre schlafenden Stammzellen wecken und den Alterungsprozess stoppen – ganz ohne teure Medikamente oder Fitnessstudio. Diese Übungen sind Ihr Schlüssel zu neuer Kraft, Balance und Unabhängigkeit bis ins hohe Alter. Haftungsausschluss: Die in diesem Video bereitgestellten Inhalte dienen ausschließlich Informations- und Bildungszwecken. Sie stellen keinen medizinischen Rat dar und ersetzen keine professionelle Diagnose oder Behandlung durch einen Arzt. #AntiAging #GesundheitAb60 #FitnessFürSenioren #Langlebigkeit #Muskelaufbau #GesundAltern #BewegungHilft #Rückenschmerzen #SeniorenSport #Vitalität https://www.youtube-nocookie.com/embed/I0_LndImjh0 1266 2025-12-13T15:00:27.000Z 2026-10-22T18:32:07.469Z https://longevityharbor.com/en/watch/I2_c3j4DGHE The 90-Year-Old Anti-Aging Hack Silicon Valley Swears By! 🧬 (Backed by Science) https://i.ytimg.com/vi/I2_c3j4DGHE/hqdefault.jpg In 1935, Dr. Clive McCay made a jaw-dropping discovery: rats that ate 30% less lived up to 50% longer. What started as an accidental finding became one of the most powerful longevity tools we know today—caloric restriction. Fast-forward to now, and Silicon Valley biohackers, scientists, and centenarians around the world are tapping into the science of fasting to slow down aging and extend their healthspan. 🔬 In this video, we break down: The surprising history of longevity research How intermittent fasting mimics the effects of caloric restriction Why “eat less, live longer” isn’t just a myth Longevity lessons from the world’s longest-living communities Why your nani’s advice to “leave space in your stomach” might be Nobel-worthy 😄 This isn’t about starving yourself—it’s about rewiring your biology for vitality and long-term health. 📌 Watch till the end to uncover anti-aging tips you can start today! https://www.youtube-nocookie.com/embed/I2_c3j4DGHE 129 2025-08-06T07:16:57.000Z 2026-10-22T18:32:09.995Z https://longevityharbor.com/de/watch/I2_c3j4DGHE The 90-Year-Old Anti-Aging Hack Silicon Valley Swears By! 🧬 (Backed by Science) https://i.ytimg.com/vi/I2_c3j4DGHE/hqdefault.jpg In 1935, Dr. Clive McCay made a jaw-dropping discovery: rats that ate 30% less lived up to 50% longer. What started as an accidental finding became one of the most powerful longevity tools we know today—caloric restriction. Fast-forward to now, and Silicon Valley biohackers, scientists, and centenarians around the world are tapping into the science of fasting to slow down aging and extend their healthspan. 🔬 In this video, we break down: The surprising history of longevity research How intermittent fasting mimics the effects of caloric restriction Why “eat less, live longer” isn’t just a myth Longevity lessons from the world’s longest-living communities Why your nani’s advice to “leave space in your stomach” might be Nobel-worthy 😄 This isn’t about starving yourself—it’s about rewiring your biology for vitality and long-term health. 📌 Watch till the end to uncover anti-aging tips you can start today! https://www.youtube-nocookie.com/embed/I2_c3j4DGHE 129 2025-08-06T07:16:57.000Z 2026-10-22T18:32:09.995Z https://longevityharbor.com/en/watch/I4z4FRoYca0 Protein restriction review: metabolic and lifespan findings https://i.ytimg.com/vi/I4z4FRoYca0/hqdefault.jpg A review described in this video says protein restriction, including limiting methionine, isoleucine and valine, improved metabolic health, mitochondrial function, senescence and lifespan in experimental evidence; early human studies suggest favorable metabolic effects, but long-term clinical outcome data are still needed. https://www.youtube-nocookie.com/embed/I4z4FRoYca0 123 2026-08-03T09:04:57.000Z 2026-10-22T23:15:35.912Z https://longevityharbor.com/de/watch/I4z4FRoYca0 Proteinrestriktions-Review: Stoffwechsel- und Lebensspannen-Befunde https://i.ytimg.com/vi/I4z4FRoYca0/hqdefault.jpg Ein im Video beschriebenes Review berichtet, dass Proteinrestriktion, einschließlich der Begrenzung von Methionin, Isoleucin und Valin, in experimentellen Daten die Stoffwechselgesundheit, Mitochondrienfunktion, Seneszenz und Lebensspanne verbesserte; frühe Humanstudien deuten auf günstige Stoffwechseleffekte hin, doch Langzeitdaten zu klinischen Endpunkten fehlen noch. https://www.youtube-nocookie.com/embed/I4z4FRoYca0 123 2026-08-03T09:04:57.000Z 2026-10-22T23:15:35.912Z https://longevityharbor.com/en/watch/I8yFF49hFbA The Literal Most Important Thing for Longevity (no exaggeration) https://i.ytimg.com/vi/I8yFF49hFbA/hqdefault.jpg Use Code THOMAS for 15% off Your First Order From Verso: http://buy.ver.so/thomas All Roads Lead to the Mitochondria This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Click HERE to Subscribe: https://www.youtube.com/c/ThomasDeLauerOfficial?sub_confirmation=1 Please check out the new Shorts channel, DeLauer Clips and Workouts, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://www.frontiersin.org/articles/10.3389/fcell.2021.628157/full#B245 https://pubmed.ncbi.nlm.nih.gov/15857398/ https://www.sciencedirect.com/science/article/pii/S0092867422013770 https://pubmed.ncbi.nlm.nih.gov/24814482/ https://pubmed.ncbi.nlm.nih.gov/15857398/ https://www.sciencedirect.com/science/article/pii/S0021925820355009 https://pubmed.ncbi.nlm.nih.gov/35446108/ https://pubmed.ncbi.nlm.nih.gov/12882352/ https://pubmed.ncbi.nlm.nih.gov/21307849/ https://www.nature.com/articles/s43587-022-00174-3 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/413815 https://pubmed.ncbi.nlm.nih.gov/18946206/ Timestamps ⏱ 0:00 - Intro 2:08 - The Mitochondria & Aging 3:15 - The 3 Hallmarks of Aging 5:24 - NAD 7:30 - 15% off Your First Order From Verso 8:46 - Mitochondria & Protein Turnover 11:18 - Ways to Reinforce & Protect Your Mitochondria https://www.youtube-nocookie.com/embed/I8yFF49hFbA 1014 2024-03-22T23:45:18.000Z 2026-10-22T19:54:19.331Z https://longevityharbor.com/de/watch/I8yFF49hFbA The Literal Most Important Thing for Longevity (no exaggeration) https://i.ytimg.com/vi/I8yFF49hFbA/hqdefault.jpg Use Code THOMAS for 15% off Your First Order From Verso: http://buy.ver.so/thomas All Roads Lead to the Mitochondria This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Click HERE to Subscribe: https://www.youtube.com/c/ThomasDeLauerOfficial?sub_confirmation=1 Please check out the new Shorts channel, DeLauer Clips and Workouts, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://www.frontiersin.org/articles/10.3389/fcell.2021.628157/full#B245 https://pubmed.ncbi.nlm.nih.gov/15857398/ https://www.sciencedirect.com/science/article/pii/S0092867422013770 https://pubmed.ncbi.nlm.nih.gov/24814482/ https://pubmed.ncbi.nlm.nih.gov/15857398/ https://www.sciencedirect.com/science/article/pii/S0021925820355009 https://pubmed.ncbi.nlm.nih.gov/35446108/ https://pubmed.ncbi.nlm.nih.gov/12882352/ https://pubmed.ncbi.nlm.nih.gov/21307849/ https://www.nature.com/articles/s43587-022-00174-3 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/413815 https://pubmed.ncbi.nlm.nih.gov/18946206/ Timestamps ⏱ 0:00 - Intro 2:08 - The Mitochondria & Aging 3:15 - The 3 Hallmarks of Aging 5:24 - NAD 7:30 - 15% off Your First Order From Verso 8:46 - Mitochondria & Protein Turnover 11:18 - Ways to Reinforce & Protect Your Mitochondria https://www.youtube-nocookie.com/embed/I8yFF49hFbA 1014 2024-03-22T23:45:18.000Z 2026-10-22T19:54:19.331Z https://longevityharbor.com/en/watch/IAyUK78Hh4E Book trailer: Heal Your Cells on cellular health and biological aging https://i.ytimg.com/vi/IAyUK78Hh4E/hqdefault.jpg The trailer presents the book Heal Your Cells by Dr. Josh Axe and Dr. Will Cole, which links cellular health to biological aging, mitochondria, metabolism, hormones, inflammation and longevity. https://www.youtube-nocookie.com/embed/IAyUK78Hh4E 187 2026-08-27T03:00:33.000Z 2026-10-22T22:41:59.212Z https://longevityharbor.com/de/watch/IAyUK78Hh4E Buchtrailer: Heal Your Cells über Zellgesundheit und biologisches Altern https://i.ytimg.com/vi/IAyUK78Hh4E/hqdefault.jpg Der Trailer stellt das Buch Heal Your Cells von Dr. Josh Axe und Dr. Will Cole vor, das Zellgesundheit mit biologischem Altern, Mitochondrien, Stoffwechsel, Hormonen, Entzündung und Langlebigkeit verbindet. https://www.youtube-nocookie.com/embed/IAyUK78Hh4E 187 2026-08-27T03:00:33.000Z 2026-10-22T22:41:59.212Z https://longevityharbor.com/en/watch/IL3E0SGEWl0 5 ESSENTIAL Exercises For People Over 60 https://i.ytimg.com/vi/IL3E0SGEWl0/hqdefault.jpg Here’s the 5 daily exercises every senior should be doing. ⏬ FREE DOWNLOADABLE EXERCISE SHEET with ALL of these exercises: https://stefan-becker.mykajabi.com/5-Essential-Exercises-For-Seniors 💥My Programs: Age Smart and fix your hip, shoulder & posture… https://stefan-becker.mykajabi.com/my-programs 🔑 Over 50? Get simple weekly tips to feel strong, mobile & pain-free again… https://stefan-becker.mykajabi.com/wind-back-the-clock 0:00 Intro 0:13 EXERCISE 1. Balance & Fall prevention 0:56 EXERCISE 2. Lower leg strength & circulation 1:40 EXERCISE 3. Reduce stooping 2:22 EXERCISE 4. Leg strength & mobility 3:28 EXERCISE 5. Upper body & core DISCLAIMER: The information contained in this video is intended as an information resource only and is not to be used or relied on for any diagnostic or treatment purposes. The video’s information does not create any patient-physician relationship and should not be used as a substitute for professional diagnosis and treatment. Do not use this video to avoid going to your own health care professional or to replace the advice they give you. Please consult your health care professional before making any health care decisions or for guidance about a specific medical condition. Body Fix Exercises makes no representations about the accuracy or suitability of this content. Body Fix Exercises and its authorised agents and contractors shall not in any event be liable for any direct or indirect damages, losses, injuries, or liability whatsoever suffered as a result of your use or misuse of this video’s content. Use of this video is at your sole risk. https://www.youtube-nocookie.com/embed/IL3E0SGEWl0 298 2023-06-09T12:43:19.000Z 2026-10-22T17:43:36.964Z https://longevityharbor.com/de/watch/IL3E0SGEWl0 5 ESSENTIAL Exercises For People Over 60 https://i.ytimg.com/vi/IL3E0SGEWl0/hqdefault.jpg Here’s the 5 daily exercises every senior should be doing. ⏬ FREE DOWNLOADABLE EXERCISE SHEET with ALL of these exercises: https://stefan-becker.mykajabi.com/5-Essential-Exercises-For-Seniors 💥My Programs: Age Smart and fix your hip, shoulder & posture… https://stefan-becker.mykajabi.com/my-programs 🔑 Over 50? Get simple weekly tips to feel strong, mobile & pain-free again… https://stefan-becker.mykajabi.com/wind-back-the-clock 0:00 Intro 0:13 EXERCISE 1. Balance & Fall prevention 0:56 EXERCISE 2. Lower leg strength & circulation 1:40 EXERCISE 3. Reduce stooping 2:22 EXERCISE 4. Leg strength & mobility 3:28 EXERCISE 5. Upper body & core DISCLAIMER: The information contained in this video is intended as an information resource only and is not to be used or relied on for any diagnostic or treatment purposes. The video’s information does not create any patient-physician relationship and should not be used as a substitute for professional diagnosis and treatment. Do not use this video to avoid going to your own health care professional or to replace the advice they give you. Please consult your health care professional before making any health care decisions or for guidance about a specific medical condition. Body Fix Exercises makes no representations about the accuracy or suitability of this content. Body Fix Exercises and its authorised agents and contractors shall not in any event be liable for any direct or indirect damages, losses, injuries, or liability whatsoever suffered as a result of your use or misuse of this video’s content. Use of this video is at your sole risk. https://www.youtube-nocookie.com/embed/IL3E0SGEWl0 298 2023-06-09T12:43:19.000Z 2026-10-22T17:43:36.964Z https://longevityharbor.com/en/watch/ILy6F85-mYU Rapamycin is the gold standard for longevity interventions https://i.ytimg.com/vi/ILy6F85-mYU/hqdefault.jpg This video is reproduced from a presentation I gave to the Euro-Geroscience Task Force "Challenges in Developing Geroscience Drug Trials" held March 23, 2022 in Toulouse, France. It gives an introduction to the state of research on rapamycin as a potential longevity and healthspan drug and some of the challenges and opportunities for clinical development. https://www.youtube-nocookie.com/embed/ILy6F85-mYU 1005 2023-06-04T15:50:02.000Z 2026-10-22T17:43:41.782Z https://longevityharbor.com/de/watch/ILy6F85-mYU Rapamycin is the gold standard for longevity interventions https://i.ytimg.com/vi/ILy6F85-mYU/hqdefault.jpg This video is reproduced from a presentation I gave to the Euro-Geroscience Task Force "Challenges in Developing Geroscience Drug Trials" held March 23, 2022 in Toulouse, France. It gives an introduction to the state of research on rapamycin as a potential longevity and healthspan drug and some of the challenges and opportunities for clinical development. https://www.youtube-nocookie.com/embed/ILy6F85-mYU 1005 2023-06-04T15:50:02.000Z 2026-10-22T17:43:41.782Z https://longevityharbor.com/en/watch/IWVCbRA6C8E Epigenetic Clock (Horvath Clock) Reveals Biological Age https://i.ytimg.com/vi/IWVCbRA6C8E/hqdefault.jpg Hopefully this now put the diet wars to rest and test our 'epigenetic age' against our chronological age! If meat and fat is indeed bad for us, you'd expect that my epigenetic age would say I'm much older than 37 years old. In January of 2020 when I get the results back, we'll find out. **I paid full retail for this test** It's not a paid promotion. ➢ Save 20% OFF this https://www.mydnage.com by using our coupon code HIH20 **They're setting up for you, will be ready soon --------------Tools that can help---------- ➢ NEW Berberine HCl blend! https://myoxcience.com/search?q=berberine ➢Fall Fasting eCourse: https://courses.highintensityhealth.com/flexible-OMAD-complete-guide ---------------------------Sleep & Camera Tools You NEED!-------------------------------- The best Blue Filtering Glasses: http://bit.ly/blueblox New REMedy Sleep Mask: http://bit.ly/2AIVbDV Gravity Blanket (use code HIH10 to save): http://bit.ly/cooling-gravity-blanket A Metabolism Book Should Have:https://amzn.to/2jUiAh5 Best Mouth Tape (Nexcare): https://amzn.to/31qJayh Red Headlamp (wear this at night around your house): https://amzn.to/2YzMGtw Breath Right Strips: https://amzn.to/31t5VSl Best iPhone Stabilizer: https://amzn.to/2IuCFFw Sony Vlog Cam: https://amzn.to/2DhRV4j My Interview Camera C100 ii: https://amzn.to/2EC5NE8 Vlog lens: Canon EF-S 17-55mm f/2.8 IS: https://amzn.to/2IGlfSo Good Audio: Rode VMPRPLUS Videomic Pro: https://amzn.to/2v9W9cm -----------------------------------------Lets Connect-------------------------------------- ➢ Facebook https://www.facebook.com/MikeMutzelMS ➢ iTunes Podcast: https://podcasts.apple.com/us/podcast/high-intensity-health-with-mike-mutzel-ms/id910048041 ➢ Instagram https://www.instagram.com/metabolic_mike ------------------------------------Show Notes-------------------------------------- Mike owns MYOXCIENCE Nutrition. If you've tried one of our cutting-edge blends, we'd be grateful for any feedback you can leave us Amazon. *These statements have not been eva https://www.youtube-nocookie.com/embed/IWVCbRA6C8E 636 2019-12-14T14:40:38.000Z 2026-10-22T17:11:30.667Z https://longevityharbor.com/de/watch/IWVCbRA6C8E Epigenetic Clock (Horvath Clock) Reveals Biological Age https://i.ytimg.com/vi/IWVCbRA6C8E/hqdefault.jpg Hopefully this now put the diet wars to rest and test our 'epigenetic age' against our chronological age! If meat and fat is indeed bad for us, you'd expect that my epigenetic age would say I'm much older than 37 years old. In January of 2020 when I get the results back, we'll find out. **I paid full retail for this test** It's not a paid promotion. ➢ Save 20% OFF this https://www.mydnage.com by using our coupon code HIH20 **They're setting up for you, will be ready soon --------------Tools that can help---------- ➢ NEW Berberine HCl blend! https://myoxcience.com/search?q=berberine ➢Fall Fasting eCourse: https://courses.highintensityhealth.com/flexible-OMAD-complete-guide ---------------------------Sleep & Camera Tools You NEED!-------------------------------- The best Blue Filtering Glasses: http://bit.ly/blueblox New REMedy Sleep Mask: http://bit.ly/2AIVbDV Gravity Blanket (use code HIH10 to save): http://bit.ly/cooling-gravity-blanket A Metabolism Book Should Have:https://amzn.to/2jUiAh5 Best Mouth Tape (Nexcare): https://amzn.to/31qJayh Red Headlamp (wear this at night around your house): https://amzn.to/2YzMGtw Breath Right Strips: https://amzn.to/31t5VSl Best iPhone Stabilizer: https://amzn.to/2IuCFFw Sony Vlog Cam: https://amzn.to/2DhRV4j My Interview Camera C100 ii: https://amzn.to/2EC5NE8 Vlog lens: Canon EF-S 17-55mm f/2.8 IS: https://amzn.to/2IGlfSo Good Audio: Rode VMPRPLUS Videomic Pro: https://amzn.to/2v9W9cm -----------------------------------------Lets Connect-------------------------------------- ➢ Facebook https://www.facebook.com/MikeMutzelMS ➢ iTunes Podcast: https://podcasts.apple.com/us/podcast/high-intensity-health-with-mike-mutzel-ms/id910048041 ➢ Instagram https://www.instagram.com/metabolic_mike ------------------------------------Show Notes-------------------------------------- Mike owns MYOXCIENCE Nutrition. If you've tried one of our cutting-edge blends, we'd be grateful for any feedback you can leave us Amazon. *These statements have not been eva https://www.youtube-nocookie.com/embed/IWVCbRA6C8E 636 2019-12-14T14:40:38.000Z 2026-10-22T17:11:30.667Z https://longevityharbor.com/en/watch/I_oIXlZfZgk Video description on aging, senescence and longevity pathways https://i.ytimg.com/vi/I_oIXlZfZgk/hqdefault.jpg The description outlines aging as time-related decline, presents genetic and environmental factors such as DNA repair, telomeres, insulin signaling and epigenetic drift, and notes animal findings on young blood and GDF11. https://www.youtube-nocookie.com/embed/I_oIXlZfZgk 1856 2026-01-03T02:17:00.000Z 2026-10-23T03:02:26.453Z https://longevityharbor.com/de/watch/I_oIXlZfZgk Videobeschreibung zu Altern, Seneszenz und Langlebigkeitswegen https://i.ytimg.com/vi/I_oIXlZfZgk/hqdefault.jpg Die Beschreibung erklärt Altern als zeitbezogenen Abbau, nennt genetische und Umweltfaktoren wie DNA-Reparatur, Telomere, Insulin-Signalweg und epigenetische Drift und erwähnt Tierbefunde zu jungem Blut und GDF11. https://www.youtube-nocookie.com/embed/I_oIXlZfZgk 1856 2026-01-03T02:17:00.000Z 2026-10-23T03:02:26.453Z https://longevityharbor.com/en/watch/IbeKK106P1o Wild plants and naturopathy: a video description on traditional foods https://i.ytimg.com/vi/IbeKK106P1o/hqdefault.jpg The description presents a video about wild plants such as watercress, hop shoots and morels, linking traditional use with naturopathy and seasonal regional eating; the video itself was not reviewed. https://www.youtube-nocookie.com/embed/IbeKK106P1o 1441 2026-06-17T11:50:20.000Z 2026-10-22T23:57:17.845Z https://longevityharbor.com/de/watch/IbeKK106P1o Wildpflanzen und Naturheilkunde: Eine Videobeschreibung zu traditionellen Lebensmitteln https://i.ytimg.com/vi/IbeKK106P1o/hqdefault.jpg Die Beschreibung stellt ein Video über Wildpflanzen wie Brunnenkresse, Hopfentriebe und Morcheln vor, das traditionelle Nutzung mit Naturheilkunde und saisonaler regionaler Ernährung verbindet; das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/IbeKK106P1o 1441 2026-06-17T11:50:20.000Z 2026-10-22T23:57:17.845Z https://longevityharbor.com/en/watch/Ic5NBtvqSSc How to reverse aging - The Power of Epigenetics, Omega-3, Vitamin D & Activity https://i.ytimg.com/vi/Ic5NBtvqSSc/hqdefault.jpg Spotify Podcast : https://open.spotify.com/show/3OFxEjictC41CCS1z2AVKe Youtube Music: https://music.youtube.com/playlist?list=PLC_3YIasstnh3L2pGuIVXBE99CxiccvL_ Apple Podcast: https://podcasts.apple.com/ca/podcast/are-you-eating-enough-protein-the-rda-plant-vs-animal/id1799242189?i=1000696852002 Are you looking to feel younger, more energized, and improve your overall well-being? In this video, we dive into the science behind epigenetics, omega-3 fatty acids, vitamin D, and physical activity—and how these factors can work together to help you feel and be younger! 🔬 Epigenetics is the study of how lifestyle choices can influence your genes, affecting your health and aging process. We'll explore how making small, positive changes can have lasting effects on your body and mind. 💪 Physical activity is one of the most powerful tools to keep your body young. From boosting your metabolism to enhancing cognitive function, discover how staying active can slow down the aging process. 🌱 Omega-3 fatty acids are essential fats that promote heart health, reduce inflammation, and support brain function. Learn how adding these to your diet can improve your health as you age. ☀️ Vitamin D plays a key role in maintaining strong bones, boosting immunity, and supporting mental health. Find out why many people are deficient and how to make sure you're getting enough! Join us as we break down these powerful concepts and provide actionable tips for incorporating them into your life. It’s time to take control of your health and age gracefully with the right habits. Don’t forget to like, subscribe, and hit the bell icon to stay updated on all things health and wellness! #epigenetic #omega3 #vitamind #healthyaging #feelyounger #fitness #wellness #antiaging #healthtips Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial: https://www.nature.com/articles/s43587-024-00793-y Can Metformin Really Add Years to Your Life https://www.youtube-nocookie.com/embed/Ic5NBtvqSSc 896 2025-02-28T20:00:17.000Z 2026-10-22T18:43:11.752Z https://longevityharbor.com/de/watch/Ic5NBtvqSSc How to reverse aging - The Power of Epigenetics, Omega-3, Vitamin D & Activity https://i.ytimg.com/vi/Ic5NBtvqSSc/hqdefault.jpg Spotify Podcast : https://open.spotify.com/show/3OFxEjictC41CCS1z2AVKe Youtube Music: https://music.youtube.com/playlist?list=PLC_3YIasstnh3L2pGuIVXBE99CxiccvL_ Apple Podcast: https://podcasts.apple.com/ca/podcast/are-you-eating-enough-protein-the-rda-plant-vs-animal/id1799242189?i=1000696852002 Are you looking to feel younger, more energized, and improve your overall well-being? In this video, we dive into the science behind epigenetics, omega-3 fatty acids, vitamin D, and physical activity—and how these factors can work together to help you feel and be younger! 🔬 Epigenetics is the study of how lifestyle choices can influence your genes, affecting your health and aging process. We'll explore how making small, positive changes can have lasting effects on your body and mind. 💪 Physical activity is one of the most powerful tools to keep your body young. From boosting your metabolism to enhancing cognitive function, discover how staying active can slow down the aging process. 🌱 Omega-3 fatty acids are essential fats that promote heart health, reduce inflammation, and support brain function. Learn how adding these to your diet can improve your health as you age. ☀️ Vitamin D plays a key role in maintaining strong bones, boosting immunity, and supporting mental health. Find out why many people are deficient and how to make sure you're getting enough! Join us as we break down these powerful concepts and provide actionable tips for incorporating them into your life. It’s time to take control of your health and age gracefully with the right habits. Don’t forget to like, subscribe, and hit the bell icon to stay updated on all things health and wellness! #epigenetic #omega3 #vitamind #healthyaging #feelyounger #fitness #wellness #antiaging #healthtips Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial: https://www.nature.com/articles/s43587-024-00793-y Can Metformin Really Add Years to Your Life https://www.youtube-nocookie.com/embed/Ic5NBtvqSSc 896 2025-02-28T20:00:17.000Z 2026-10-22T18:43:11.752Z https://longevityharbor.com/en/watch/IeFyAsV455E Video asks whether astaxanthin or NMN is better for anti-aging https://i.ytimg.com/vi/IeFyAsV455E/hqdefault.jpg The description only poses the question of whether astaxanthin or NMN should be taken for anti-aging; it gives no comparison, results or recommendation. https://www.youtube-nocookie.com/embed/IeFyAsV455E 113 2026-07-22T19:55:42.000Z 2026-10-22T23:24:47.293Z https://longevityharbor.com/de/watch/IeFyAsV455E Video fragt, ob Astaxanthin oder NMN besser gegen Altern wirkt https://i.ytimg.com/vi/IeFyAsV455E/hqdefault.jpg Die Beschreibung stellt nur die Frage, ob man Astaxanthin oder NMN gegen das Altern einnehmen sollte; sie liefert keinen Vergleich, keine Ergebnisse und keine Empfehlung. https://www.youtube-nocookie.com/embed/IeFyAsV455E 113 2026-07-22T19:55:42.000Z 2026-10-22T23:24:47.293Z https://longevityharbor.com/en/watch/IfQAE5km_GY Biohacking: From Wellness to Longevity, Backed by Data https://i.ytimg.com/vi/IfQAE5km_GY/hqdefault.jpg Cold plunges. Red light masks. Mushroom lattes. Everyone’s a biohacker... until it’s time to explain mTOR or senolytics. Here’s what’s real, what’s hype, and what I actually do - from peptides to plasma exchange. Not for TikTok clout. For mitochondrial function, cognitive resilience, and staying forever 21, in function, not fantasy. https://www.youtube-nocookie.com/embed/IfQAE5km_GY 178 2025-08-05T13:00:35.000Z 2026-10-22T19:54:21.175Z https://longevityharbor.com/de/watch/IfQAE5km_GY Biohacking: From Wellness to Longevity, Backed by Data https://i.ytimg.com/vi/IfQAE5km_GY/hqdefault.jpg Cold plunges. Red light masks. Mushroom lattes. Everyone’s a biohacker... until it’s time to explain mTOR or senolytics. Here’s what’s real, what’s hype, and what I actually do - from peptides to plasma exchange. Not for TikTok clout. For mitochondrial function, cognitive resilience, and staying forever 21, in function, not fantasy. https://www.youtube-nocookie.com/embed/IfQAE5km_GY 178 2025-08-05T13:00:35.000Z 2026-10-22T19:54:21.175Z https://longevityharbor.com/en/watch/Ifx5GQQxl4k NMN and aging: what a video description says about mouse studies and human trials https://i.ytimg.com/vi/Ifx5GQQxl4k/hqdefault.jpg The description says NMN research began with a 2013 Harvard mouse study and that translating such laboratory results into human health outcomes is far more complex than marketing suggests. https://www.youtube-nocookie.com/embed/Ifx5GQQxl4k 1261 2026-09-07T21:00:22.000Z 2026-10-22T22:27:38.906Z https://longevityharbor.com/de/watch/Ifx5GQQxl4k NMN und Altern: Was eine Videobeschreibung zu Mausstudien und Humanstudien sagt https://i.ytimg.com/vi/Ifx5GQQxl4k/hqdefault.jpg Laut Beschreibung begann die NMN-Forschung mit einer Harvard-Mausstudie von 2013; die Übertragung solcher Laborergebnisse auf menschliche Gesundheitsergebnisse sei weit komplexer, als Marketing nahelegt. https://www.youtube-nocookie.com/embed/Ifx5GQQxl4k 1261 2026-09-07T21:00:22.000Z 2026-10-22T22:27:38.906Z https://longevityharbor.com/en/watch/IgX3UeN6s3s Fight Aging With Natural Senolytics? #strawberries #health #fisetin #senolytics #longevity https://i.ytimg.com/vi/IgX3UeN6s3s/hqdefault.jpg What if aging isn't about getting older... but about your cells turning into zombies? Seriously! As we age, some of our cells become "senescent." They don't die, but they don't work properly either. Instead, they just hang out, causing inflammation and damaging the healthy cells around them. Scientists call them "zombie cells." These zombie cells are a major reason why our blood vessels get stiffer as we get older, leading to heart disease. But what if we could just... remove them? Meet the "senolytics," a class of drugs that can hunt down and eliminate these zombie cells. A new study on old mice just gave us more exciting data on one of them: a natural compound called Fisetin, found in strawberries and apples! Scientists gave old mice a special Fisetin supplement. The result? Their blood vessels had far fewer zombie cells, less inflammation, and worked much better, almost like they were young again! So, should you just eat a truckload of strawberries? Not so fast. The dose used in these mouse studies is equivalent to a HUGE amount for a human, way more than you could ever eat. This is about concentrated, pharmaceutical-grade supplements, not just your daily fruit salad. And here's the most important part: This is still mouse data. While the results are incredibly promising, we are still waiting for the final, published proof that Fisetin works the same way in people. Other senolytics have that human proof, but Fisetin is still in the testing phase. So, what's the bottom line? The Science is Amazing: The idea of clearing "zombie cells" to fight aging is a real and revolutionary field of science. Fisetin is Promising: In mice, it looks like a powerful senolytic, especially for improving blood vessel health. We Need More Data: Don't believe hype about miracle supplements yet. We need to wait for the human trials to finish. This research is a thrilling step forward. It shows we're getting closer to targeting the root causes of aging. But for now, the best advice is to stay curious, follow the sc https://www.youtube-nocookie.com/embed/IgX3UeN6s3s 126 2025-10-28T15:40:06.000Z 2026-10-22T19:21:21.998Z https://longevityharbor.com/de/watch/IgX3UeN6s3s Fight Aging With Natural Senolytics? #strawberries #health #fisetin #senolytics #longevity https://i.ytimg.com/vi/IgX3UeN6s3s/hqdefault.jpg What if aging isn't about getting older... but about your cells turning into zombies? Seriously! As we age, some of our cells become "senescent." They don't die, but they don't work properly either. Instead, they just hang out, causing inflammation and damaging the healthy cells around them. Scientists call them "zombie cells." These zombie cells are a major reason why our blood vessels get stiffer as we get older, leading to heart disease. But what if we could just... remove them? Meet the "senolytics," a class of drugs that can hunt down and eliminate these zombie cells. A new study on old mice just gave us more exciting data on one of them: a natural compound called Fisetin, found in strawberries and apples! Scientists gave old mice a special Fisetin supplement. The result? Their blood vessels had far fewer zombie cells, less inflammation, and worked much better, almost like they were young again! So, should you just eat a truckload of strawberries? Not so fast. The dose used in these mouse studies is equivalent to a HUGE amount for a human, way more than you could ever eat. This is about concentrated, pharmaceutical-grade supplements, not just your daily fruit salad. And here's the most important part: This is still mouse data. While the results are incredibly promising, we are still waiting for the final, published proof that Fisetin works the same way in people. Other senolytics have that human proof, but Fisetin is still in the testing phase. So, what's the bottom line? The Science is Amazing: The idea of clearing "zombie cells" to fight aging is a real and revolutionary field of science. Fisetin is Promising: In mice, it looks like a powerful senolytic, especially for improving blood vessel health. We Need More Data: Don't believe hype about miracle supplements yet. We need to wait for the human trials to finish. This research is a thrilling step forward. It shows we're getting closer to targeting the root causes of aging. But for now, the best advice is to stay curious, follow the sc https://www.youtube-nocookie.com/embed/IgX3UeN6s3s 126 2025-10-28T15:40:06.000Z 2026-10-22T19:21:21.998Z https://longevityharbor.com/en/watch/IkNt29jSM8E 🔬 Can We REVERSE Aging with NMN? The NAD+ Breakthrough Explained https://i.ytimg.com/vi/IkNt29jSM8E/hqdefault.jpg 🔬 Can We REVERSE Aging with NMN? The NAD+ Breakthrough Explained ➡️GET YOUR NMN: https://shopsolensis.com/products/nmn-nicotinamide-mononucleotide-15-grams By middle age, your NAD+ levels have PLUMMETED by 50%—and this dramatic decline is driving every aspect of aging. But what if we could restore it? Enter NMN (Nicotinamide Mononucleotide), the molecule that's rewriting the rules of aging science. In 2018, the WHO officially classified aging as a disease for the first time in history. This single decision opened the floodgates for anti-aging research, and NAD+ restoration through NMN supplementation is leading the charge. 🎯 What You'll Discover: ✅ Why NAD+ is your body's "cellular maintenance crew" ✅ The shocking 50% decline by middle age ✅ How NMN works as a direct NAD+ precursor ✅ The VIP transporter that gets NMN into your cells ✅ Jaw-dropping results from animal studies ✅ What David Sinclair's personal results reveal ✅ The double-whammy aging problem and how to fix it ✅ Early human trial results and expert predictions Featuring insights from Harvard's Dr. David Sinclair (who takes NMN himself at 60 with biomarkers of a 31-year-old) and Dr. Shin-ichiro Imai, who predicts NMN could make your metabolism 10-20 years younger. ⏱️ VIDEO CHAPTERS: 0:00 - The Shocking 50% Decline 0:37 - The Double Whammy of Aging 1:01 - Historic Shift: Aging as a Disease 1:32 - What is NAD+ and Why It Matters 2:00 - Meet NMN: The NAD+ Precursor 2:28 - Why Diet Alone Isn't Enough 2:44 - How NMN Gets Into Your Cells 3:14 - The Age-Related Bottleneck Problem 3:32 - Jaw-Dropping Results in Mice 4:10 - Neuroprotective Effects 4:46 - Why Older Mice Benefit More 4:48 - The Big Question: Human Translation 5:10 - David Sinclair's Personal Results 5:28 - Expert Predictions for Humans 5:43 - Are We Ready to Treat Aging Itself? 📊 KEY STATS: - 50% NAD+ decline by middle age - David Sinclair (60) has biomarkers of a 31-year-old - Potential to restore metabolism by 10-20 years 🔔 Subscribe for evidence-based longevity breakthroughs 💬 Co https://www.youtube-nocookie.com/embed/IkNt29jSM8E 363 2026-01-15T18:31:20.000Z 2026-10-22T17:43:42.530Z https://longevityharbor.com/de/watch/IkNt29jSM8E 🔬 Can We REVERSE Aging with NMN? The NAD+ Breakthrough Explained https://i.ytimg.com/vi/IkNt29jSM8E/hqdefault.jpg 🔬 Can We REVERSE Aging with NMN? The NAD+ Breakthrough Explained ➡️GET YOUR NMN: https://shopsolensis.com/products/nmn-nicotinamide-mononucleotide-15-grams By middle age, your NAD+ levels have PLUMMETED by 50%—and this dramatic decline is driving every aspect of aging. But what if we could restore it? Enter NMN (Nicotinamide Mononucleotide), the molecule that's rewriting the rules of aging science. In 2018, the WHO officially classified aging as a disease for the first time in history. This single decision opened the floodgates for anti-aging research, and NAD+ restoration through NMN supplementation is leading the charge. 🎯 What You'll Discover: ✅ Why NAD+ is your body's "cellular maintenance crew" ✅ The shocking 50% decline by middle age ✅ How NMN works as a direct NAD+ precursor ✅ The VIP transporter that gets NMN into your cells ✅ Jaw-dropping results from animal studies ✅ What David Sinclair's personal results reveal ✅ The double-whammy aging problem and how to fix it ✅ Early human trial results and expert predictions Featuring insights from Harvard's Dr. David Sinclair (who takes NMN himself at 60 with biomarkers of a 31-year-old) and Dr. Shin-ichiro Imai, who predicts NMN could make your metabolism 10-20 years younger. ⏱️ VIDEO CHAPTERS: 0:00 - The Shocking 50% Decline 0:37 - The Double Whammy of Aging 1:01 - Historic Shift: Aging as a Disease 1:32 - What is NAD+ and Why It Matters 2:00 - Meet NMN: The NAD+ Precursor 2:28 - Why Diet Alone Isn't Enough 2:44 - How NMN Gets Into Your Cells 3:14 - The Age-Related Bottleneck Problem 3:32 - Jaw-Dropping Results in Mice 4:10 - Neuroprotective Effects 4:46 - Why Older Mice Benefit More 4:48 - The Big Question: Human Translation 5:10 - David Sinclair's Personal Results 5:28 - Expert Predictions for Humans 5:43 - Are We Ready to Treat Aging Itself? 📊 KEY STATS: - 50% NAD+ decline by middle age - David Sinclair (60) has biomarkers of a 31-year-old - Potential to restore metabolism by 10-20 years 🔔 Subscribe for evidence-based longevity breakthroughs 💬 Co https://www.youtube-nocookie.com/embed/IkNt29jSM8E 363 2026-01-15T18:31:20.000Z 2026-10-22T17:43:42.530Z https://longevityharbor.com/en/watch/IkU1aLZ1L1A Video description: GLP-1 drugs, IL-6 and brown fat, with TERT in a Dulaglutide study https://i.ytimg.com/vi/IkU1aLZ1L1A/hqdefault.jpg The description attributes to Dr. Kolonin's lab the finding that GLP-1 drugs cause a transient IL-6 spike in fat tissue that converts white fat cells into brown fat cells; in a clinical study of Dulaglutide-treated patients, those who upregulated IL-6 also showed elevated TERT expression. https://www.youtube-nocookie.com/embed/IkU1aLZ1L1A 1610 2026-03-31T16:00:00.000Z 2026-10-23T01:49:58.361Z https://longevityharbor.com/de/watch/IkU1aLZ1L1A Videobeschreibung: GLP-1-Medikamente, IL-6 und braunes Fett, mit TERT in einer Dulaglutid-Studie https://i.ytimg.com/vi/IkU1aLZ1L1A/hqdefault.jpg Die Beschreibung schreibt Dr. Kolonins Labor den Befund zu, dass GLP-1-Medikamente einen vorübergehenden IL-6-Anstieg im Fettgewebe auslösen, der weiße Fettzellen in braune Fettzellen umwandelt; in einer klinischen Studie an mit Dulaglutid behandelten Patienten zeigten diejenigen, bei denen IL-6 hochreguliert wurde, auch eine erhöhte TERT-Expression. https://www.youtube-nocookie.com/embed/IkU1aLZ1L1A 1610 2026-03-31T16:00:00.000Z 2026-10-23T01:49:58.361Z https://longevityharbor.com/en/watch/IlWv417axEQ Video description: three nutrients and blurry vision after 60 https://i.ytimg.com/vi/IlWv417axEQ/hqdefault.jpg The description says Dr. Yashwant Singh presents three nutrients linked to eye health after 60: lutein and zeaxanthin for the macula, DHA for photoreceptor cells and vitamin B12 for optic neuropathy. It cites AREDS2 with 4,203 participants and a 26% reduction in macular degeneration. These are creator claims from the description only. https://www.youtube-nocookie.com/embed/IlWv417axEQ 167 2026-04-17T18:55:22.000Z 2026-10-23T01:32:56.077Z https://longevityharbor.com/de/watch/IlWv417axEQ Videobeschreibung: drei Nährstoffe und verschwommenes Sehen nach 60 https://i.ytimg.com/vi/IlWv417axEQ/hqdefault.jpg Laut Beschreibung stellt Dr. Yashwant Singh drei Nährstoffe für die Augengesundheit nach 60 vor: Lutein und Zeaxanthin für die Makula, DHA für Fotorezeptorzellen und Vitamin B12 bei Optikusneuropathie. Er nennt AREDS2 mit 4.203 Teilnehmenden und 26 % weniger Makuladegeneration. Das sind Angaben des Erstellers aus der Beschreibung. https://www.youtube-nocookie.com/embed/IlWv417axEQ 167 2026-04-17T18:55:22.000Z 2026-10-23T01:32:56.077Z https://longevityharbor.com/en/watch/Io88VabNlps The Reversal of Muscle Aging https://i.ytimg.com/vi/Io88VabNlps/hqdefault.jpg This research identifies the transcription factor **DEAF1** as a primary driver of age-related muscle decline by directly increasing the expression of the growth regulator **mTORC1**. In aging muscle, a lack of suppression from **FOXO** signaling allows **DEAF1** levels to rise, leading to protein imbalances, impaired cellular cleaning via autophagy, and tissue senescence. The study demonstrates that **exercise** naturally reverses this process by activating **FOXO**, which in turn represses **DEAF1** to normalize muscle metabolism. These findings were validated across multiple species, confirming that the **FOXO–DEAF1–mTORC1** pathway is an evolutionarily conserved mechanism. By pinpointing this specific genetic axis, the authors highlight new therapeutic opportunities for treating **sarcopenia** and preserving physical vitality in the elderly. The results suggest that targeted medical interventions could potentially mimic the molecular benefits of physical activity to restore muscle health. https://www.youtube-nocookie.com/embed/Io88VabNlps 329 2026-08-13T03:39:17.000Z 2026-10-22T19:54:22.334Z https://longevityharbor.com/de/watch/Io88VabNlps The Reversal of Muscle Aging https://i.ytimg.com/vi/Io88VabNlps/hqdefault.jpg This research identifies the transcription factor **DEAF1** as a primary driver of age-related muscle decline by directly increasing the expression of the growth regulator **mTORC1**. In aging muscle, a lack of suppression from **FOXO** signaling allows **DEAF1** levels to rise, leading to protein imbalances, impaired cellular cleaning via autophagy, and tissue senescence. The study demonstrates that **exercise** naturally reverses this process by activating **FOXO**, which in turn represses **DEAF1** to normalize muscle metabolism. These findings were validated across multiple species, confirming that the **FOXO–DEAF1–mTORC1** pathway is an evolutionarily conserved mechanism. By pinpointing this specific genetic axis, the authors highlight new therapeutic opportunities for treating **sarcopenia** and preserving physical vitality in the elderly. The results suggest that targeted medical interventions could potentially mimic the molecular benefits of physical activity to restore muscle health. https://www.youtube-nocookie.com/embed/Io88VabNlps 329 2026-08-13T03:39:17.000Z 2026-10-22T19:54:22.334Z https://longevityharbor.com/en/watch/IoaRBrcdycc Exercise: Better Than Fasting, Calorie Restriction for Aging, Longevity? https://i.ytimg.com/vi/IoaRBrcdycc/hqdefault.jpg Fasting and calorie restriction are not the only tools that support longevity. Support your Sleep and Electrolyte levels with Myo Relax by MYOXCIENCE Nutrition: http://bit.ly/2HgCPOs Save with code: Podcast More about today's show: Link to studies and references: https://bit.ly/3g4xxXM Fasting and calorie restriction are not the only tools that support longevity. Harvard researchers make the case that exercise is the ultimate tool to support longevity and healthy aging. --------------Sleep & Camera Tools You NEED!----------------------- Best Sleep Mask: http://bit.ly/2AIVbDV Blue Blocking Glasses: http://bit.ly/blueblox Gravity Blanket (use code HIH10 to save): http://bit.ly/cooling-gravity-blanket A Metabolism Book Should Have:https://amzn.to/2jUiAh5 Red Headlamp (wear this at night around your house): https://amzn.to/2YzMGtw Breath Right Strips: https://amzn.to/31t5VSl Best iPhone Stabilizer: https://amzn.to/2IuCFFw My Interview Camera C100 ii: https://amzn.to/2EC5NE8 Vlog lens: Canon EF-S 17-55mm f/2.8 IS: https://amzn.to/2IGlfSo Good Audio: Rode VMPRPLUS Videomic Pro: https://amzn.to/2v9W9cm -----------------------------------------Show Notes-------------------------------------- 0:00 Intro 0:51 Exercise impacts aging 1:55 9 Hallmarks of Aging 2:36 Genome instability 3:27 Epigenetic /Biologic age testing 4:00 Mitochondrial Dysfunction and exercise 6:00 Exercise and Aging Specifics 8:14 Sleep Loss and Aging 10:00 Exercise May be Better Than Fasting for Aging 11:21 Exercise and aging of the heart 11:45 How much exercise do you need 12:34 Muscle Loss with Age 15:43 Exercise and the brain 18:06 Exercise and Nutrient Sensing 20:01 Exercise, mTOR and AMPK https://www.youtube-nocookie.com/embed/IoaRBrcdycc 1543 2021-08-14T17:41:01.000Z 2026-10-22T17:43:38.464Z https://longevityharbor.com/de/watch/IoaRBrcdycc Exercise: Better Than Fasting, Calorie Restriction for Aging, Longevity? https://i.ytimg.com/vi/IoaRBrcdycc/hqdefault.jpg Fasting and calorie restriction are not the only tools that support longevity. Support your Sleep and Electrolyte levels with Myo Relax by MYOXCIENCE Nutrition: http://bit.ly/2HgCPOs Save with code: Podcast More about today's show: Link to studies and references: https://bit.ly/3g4xxXM Fasting and calorie restriction are not the only tools that support longevity. Harvard researchers make the case that exercise is the ultimate tool to support longevity and healthy aging. --------------Sleep & Camera Tools You NEED!----------------------- Best Sleep Mask: http://bit.ly/2AIVbDV Blue Blocking Glasses: http://bit.ly/blueblox Gravity Blanket (use code HIH10 to save): http://bit.ly/cooling-gravity-blanket A Metabolism Book Should Have:https://amzn.to/2jUiAh5 Red Headlamp (wear this at night around your house): https://amzn.to/2YzMGtw Breath Right Strips: https://amzn.to/31t5VSl Best iPhone Stabilizer: https://amzn.to/2IuCFFw My Interview Camera C100 ii: https://amzn.to/2EC5NE8 Vlog lens: Canon EF-S 17-55mm f/2.8 IS: https://amzn.to/2IGlfSo Good Audio: Rode VMPRPLUS Videomic Pro: https://amzn.to/2v9W9cm -----------------------------------------Show Notes-------------------------------------- 0:00 Intro 0:51 Exercise impacts aging 1:55 9 Hallmarks of Aging 2:36 Genome instability 3:27 Epigenetic /Biologic age testing 4:00 Mitochondrial Dysfunction and exercise 6:00 Exercise and Aging Specifics 8:14 Sleep Loss and Aging 10:00 Exercise May be Better Than Fasting for Aging 11:21 Exercise and aging of the heart 11:45 How much exercise do you need 12:34 Muscle Loss with Age 15:43 Exercise and the brain 18:06 Exercise and Nutrient Sensing 20:01 Exercise, mTOR and AMPK https://www.youtube-nocookie.com/embed/IoaRBrcdycc 1543 2021-08-14T17:41:01.000Z 2026-10-22T17:43:38.464Z https://longevityharbor.com/en/watch/IqDpzHMnyPM Epigenetic Clock Studies in Companion Animals https://i.ytimg.com/vi/IqDpzHMnyPM/hqdefault.jpg https://www.purinainstitute.com/event/epigenetic-clock-studies-companion-animals Epigenetic clocks, which can be used to predict biological age from DNA methylation data, are one tool that researchers now use to evaluate anti-aging interventions in preclinical and clinical studies. Why build an epigenetic clock for companion animals? Dr. Steve Horvath explains the premise and promise of epigenetic clocks, and how they may facilitate the translation of interventions from humans to pets and vice versa. ______________________________________ At the Purina Institute, we believe science is more powerful when it’s shared. We empower veterinary professionals to put nutrition at the forefront of pet health discussions to further improve and extend the healthy lives of pets through nutrition. On our channel you will find videos on a range of topics: ● Webinars ● Expert talking heads ● Role play videos And much more to help you in your daily veterinary practice and help pets live longer, healthier lives. Subscribe to Purina Institute: https://www.youtube.com/@PurinaInstitute Where to find Purina Institute: WEBSITE: https://www.purinainstitute.com/ LINKEDIN: https://www.linkedin.com/company/purina-institute FACEBOOK: https://www.facebook.com/PurinaInstitute INSTAGRAM: https://www.instagram.com/purinainstitute/ TWITTER: https://twitter.com/PurinaInstitute Putting the power of nutrition science into practice. #VeterinaryScience #VeterinaryMedicine #VeterinarySupport #VeterinarianLife #Veterinarian https://www.youtube-nocookie.com/embed/IqDpzHMnyPM 2875 2023-11-28T20:03:32.000Z 2026-10-22T18:54:04.177Z https://longevityharbor.com/de/watch/IqDpzHMnyPM Epigenetic Clock Studies in Companion Animals https://i.ytimg.com/vi/IqDpzHMnyPM/hqdefault.jpg https://www.purinainstitute.com/event/epigenetic-clock-studies-companion-animals Epigenetic clocks, which can be used to predict biological age from DNA methylation data, are one tool that researchers now use to evaluate anti-aging interventions in preclinical and clinical studies. Why build an epigenetic clock for companion animals? Dr. Steve Horvath explains the premise and promise of epigenetic clocks, and how they may facilitate the translation of interventions from humans to pets and vice versa. ______________________________________ At the Purina Institute, we believe science is more powerful when it’s shared. We empower veterinary professionals to put nutrition at the forefront of pet health discussions to further improve and extend the healthy lives of pets through nutrition. On our channel you will find videos on a range of topics: ● Webinars ● Expert talking heads ● Role play videos And much more to help you in your daily veterinary practice and help pets live longer, healthier lives. Subscribe to Purina Institute: https://www.youtube.com/@PurinaInstitute Where to find Purina Institute: WEBSITE: https://www.purinainstitute.com/ LINKEDIN: https://www.linkedin.com/company/purina-institute FACEBOOK: https://www.facebook.com/PurinaInstitute INSTAGRAM: https://www.instagram.com/purinainstitute/ TWITTER: https://twitter.com/PurinaInstitute Putting the power of nutrition science into practice. #VeterinaryScience #VeterinaryMedicine #VeterinarySupport #VeterinarianLife #Veterinarian https://www.youtube-nocookie.com/embed/IqDpzHMnyPM 2875 2023-11-28T20:03:32.000Z 2026-10-22T18:54:04.177Z https://longevityharbor.com/en/watch/Iqfqdkuwe28 Rapamycin & Senolytics: The Science of Slowing Aging & Extending Lifespan https://i.ytimg.com/vi/Iqfqdkuwe28/hqdefault.jpg Can we slow down aging and improve healthspan? Rapamycin and Senolytics are two of the most talked-about longevity breakthroughs that may hold the key to cellular rejuvenation, disease prevention, and a longer, healthier life. In this video, we break down: What Rapamycin is and how it works to extend lifespan How Senolytics clear out aging cells to improve health The latest research, potential benefits, and risks Should you consider them for longevity? Don't miss this deep dive into the future of anti-aging science! Watch now and take control of your aging process! Subscribe for more longevity insights: https://www.youtube.com/@UC7jh8dNPhqtk9ryE8WITgAg #Rapamycin #Senolytics #Longevity #AntiAging #HealthyAging #Biohacking #Lifespan #FutureOfHealth #CellularHealth #RegenerativeMedicine https://www.youtube-nocookie.com/embed/Iqfqdkuwe28 261 2025-02-24T01:00:06.000Z 2026-10-22T19:54:22.459Z https://longevityharbor.com/de/watch/Iqfqdkuwe28 Rapamycin & Senolytics: The Science of Slowing Aging & Extending Lifespan https://i.ytimg.com/vi/Iqfqdkuwe28/hqdefault.jpg Can we slow down aging and improve healthspan? Rapamycin and Senolytics are two of the most talked-about longevity breakthroughs that may hold the key to cellular rejuvenation, disease prevention, and a longer, healthier life. In this video, we break down: What Rapamycin is and how it works to extend lifespan How Senolytics clear out aging cells to improve health The latest research, potential benefits, and risks Should you consider them for longevity? Don't miss this deep dive into the future of anti-aging science! Watch now and take control of your aging process! Subscribe for more longevity insights: https://www.youtube.com/@UC7jh8dNPhqtk9ryE8WITgAg #Rapamycin #Senolytics #Longevity #AntiAging #HealthyAging #Biohacking #Lifespan #FutureOfHealth #CellularHealth #RegenerativeMedicine https://www.youtube-nocookie.com/embed/Iqfqdkuwe28 261 2025-02-24T01:00:06.000Z 2026-10-22T19:54:22.459Z https://longevityharbor.com/en/watch/IrfBCWadCm0 Biologist Matt Kaeberlein on Longevity Hype, Fasting, Rapamycin and Biological Age Tests https://i.ytimg.com/vi/IrfBCWadCm0/hqdefault.jpg In this video description, biologist Matt Kaeberlein is presented as skeptical of direct-to-consumer longevity products and as questioning what data say about rapamycin and intermittent fasting; the description also lists topics such as biological age tests and the Dog Aging Project's rapamycin trial. https://www.youtube-nocookie.com/embed/IrfBCWadCm0 5102 2026-10-13T15:30:10.000Z 2026-10-22T19:57:49.720Z https://longevityharbor.com/de/watch/IrfBCWadCm0 Biologe Matt Kaeberlein über Longevity-Hype, Fasten, Rapamycin und biologische Alterstests https://i.ytimg.com/vi/IrfBCWadCm0/hqdefault.jpg In dieser Videobeschreibung wird der Biologe Matt Kaeberlein als skeptisch gegenüber direkt an Verbraucher gerichteten Longevity-Produkten dargestellt und als jemand, der hinterfragt, was Daten zu Rapamycin und Intervallfasten sagen; zudem listet die Beschreibung Themen wie biologische Alterstests und die Rapamycin-Studie des Dog Aging Project. https://www.youtube-nocookie.com/embed/IrfBCWadCm0 5102 2026-10-13T15:30:10.000Z 2026-10-22T19:57:49.720Z https://longevityharbor.com/en/watch/IrpiT_57oCk mTOR review: overactive signaling, autophagy and proposed anti-aging drugs https://i.ytimg.com/vi/IrpiT_57oCk/hqdefault.jpg This scientific review describes mTOR as a central regulator of biological aging and age-related disease and discusses inhibitors such as rapamycin, curcumin and resveratrol, while stressing that dosing must be refined to limit side effects. https://www.youtube-nocookie.com/embed/IrpiT_57oCk 539 2026-06-21T21:14:27.000Z 2026-10-22T23:53:12.956Z https://longevityharbor.com/de/watch/IrpiT_57oCk mTOR-Review: überaktive Signalwege, Autophagie und vorgeschlagene Anti-Aging-Wirkstoffe https://i.ytimg.com/vi/IrpiT_57oCk/hqdefault.jpg Dieses wissenschaftliche Review beschreibt mTOR als zentralen Regulator des biologischen Alterns und altersbezogener Erkrankungen und erörtert Hemmstoffe wie Rapamycin, Curcumin und Resveratrol; zugleich betont es, dass die Dosierung verfeinert werden muss, um Nebenwirkungen zu begrenzen. https://www.youtube-nocookie.com/embed/IrpiT_57oCk 539 2026-06-21T21:14:27.000Z 2026-10-22T23:53:12.956Z https://longevityharbor.com/en/watch/It2mSGiqxas Rapamycin, mTOR and lifespan: what the video description claims https://i.ytimg.com/vi/It2mSGiqxas/hqdefault.jpg The description says rapamycin, an mTOR inhibitor, affects lifespan and healthspan by mimicking calorie restriction, and that mTOR is central to growth, stress resistance and autophagy. No study data are given. https://www.youtube-nocookie.com/embed/It2mSGiqxas 103 2026-06-01T22:00:41.000Z 2026-10-23T00:07:48.001Z https://longevityharbor.com/de/watch/It2mSGiqxas Rapamycin, mTOR und Lebensspanne: Was die Videobeschreibung behauptet https://i.ytimg.com/vi/It2mSGiqxas/hqdefault.jpg Die Beschreibung sagt, Rapamycin, ein mTOR-Hemmer, beeinflusse Lebens- und Gesundheitsspanne durch Nachahmung von Kalorienrestriktion, und mTOR sei zentral für Wachstum, Stressresistenz und Autophagie. Studiendaten fehlen. https://www.youtube-nocookie.com/embed/It2mSGiqxas 103 2026-06-01T22:00:41.000Z 2026-10-23T00:07:48.001Z https://longevityharbor.com/en/watch/IuIfsMi3NEI I read every human NMN study: Is it a Health Scam? https://i.ytimg.com/vi/IuIfsMi3NEI/hqdefault.jpg *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity *EMAIL LIST* One Weekly Email of Value: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* https://bit.ly/3dmUl2H *DONATIONS FOR A SCIENCE BASED CAUSE* Patreon: https://bit.ly/PhysionicPatreon *OTHER SOCIAL MEDIA* Instagram: http://bit.ly/2OBFe7i Next Video: https://youtu.be/kK-fvUimdKI References [1] Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013 [2] Irie J, Inagaki E, Fujita M, et al. Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men. Endocr J. 2020;67(2):153-160. doi:10.1507/endocrj.EJ19-0313 [3] Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985 [4] Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186/s12970-021-00442-4 [5] Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390/nu14040755 [6] Okabe K, Yaku K, Uchida Y, et al. Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects. Front Nutr. 2022;9:868640. Published 2022 Apr 11. doi:10.3389/fnut.2022.868640 [7] Huang H. A Multi https://www.youtube-nocookie.com/embed/IuIfsMi3NEI 668 2023-09-25T12:00:25.000Z 2026-10-23T00:51:10.578Z https://longevityharbor.com/de/watch/IuIfsMi3NEI I read every human NMN study: Is it a Health Scam? https://i.ytimg.com/vi/IuIfsMi3NEI/hqdefault.jpg *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity *EMAIL LIST* One Weekly Email of Value: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* https://bit.ly/3dmUl2H *DONATIONS FOR A SCIENCE BASED CAUSE* Patreon: https://bit.ly/PhysionicPatreon *OTHER SOCIAL MEDIA* Instagram: http://bit.ly/2OBFe7i Next Video: https://youtu.be/kK-fvUimdKI References [1] Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013 [2] Irie J, Inagaki E, Fujita M, et al. Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men. Endocr J. 2020;67(2):153-160. doi:10.1507/endocrj.EJ19-0313 [3] Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985 [4] Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186/s12970-021-00442-4 [5] Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390/nu14040755 [6] Okabe K, Yaku K, Uchida Y, et al. Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects. Front Nutr. 2022;9:868640. Published 2022 Apr 11. doi:10.3389/fnut.2022.868640 [7] Huang H. A Multi https://www.youtube-nocookie.com/embed/IuIfsMi3NEI 668 2023-09-25T12:00:25.000Z 2026-10-23T00:51:10.578Z https://longevityharbor.com/en/watch/IvQbVSsjhkY Causes and Consequences of Epigenetic Clocks https://i.ytimg.com/vi/IvQbVSsjhkY/hqdefault.jpg ABMR Keynote Address #2: Causes and consequences of epigenetic clocks with Steve Horvath, PhD, (University of California, Los Angeles) . https://www.youtube-nocookie.com/embed/IvQbVSsjhkY 2772 2022-06-17T22:09:35.000Z 2026-10-22T17:43:35.315Z https://longevityharbor.com/de/watch/IvQbVSsjhkY Causes and Consequences of Epigenetic Clocks https://i.ytimg.com/vi/IvQbVSsjhkY/hqdefault.jpg ABMR Keynote Address #2: Causes and consequences of epigenetic clocks with Steve Horvath, PhD, (University of California, Los Angeles) . https://www.youtube-nocookie.com/embed/IvQbVSsjhkY 2772 2022-06-17T22:09:35.000Z 2026-10-22T17:43:35.315Z https://longevityharbor.com/en/watch/Iwir02liSmQ Talk on rapamycin trials for healthy aging in humans https://i.ytimg.com/vi/Iwir02liSmQ/hqdefault.jpg In this video description, Adam R. Konopka, PhD, presents translational geroscience and asks whether rapamycin, an FDA-approved drug, can safely support aspects of healthy aging in humans, based on his team's ongoing clinical trials at UW–Madison. https://www.youtube-nocookie.com/embed/Iwir02liSmQ 1965 2025-12-08T19:38:31.000Z 2026-10-23T03:17:34.064Z https://longevityharbor.com/de/watch/Iwir02liSmQ Vortrag über Rapamycin-Studien zu gesundem Altern beim Menschen https://i.ytimg.com/vi/Iwir02liSmQ/hqdefault.jpg In dieser Videobeschreibung stellt Adam R. Konopka, PhD, die translationale Gerowissenschaft vor und fragt, ob Rapamycin, ein von der FDA zugelassenes Medikament, Aspekte gesunden Alterns beim Menschen sicher unterstützen kann; Grundlage sind laufende klinische Studien seines Teams an der UW–Madison. https://www.youtube-nocookie.com/embed/Iwir02liSmQ 1965 2025-12-08T19:38:31.000Z 2026-10-23T03:17:34.064Z https://longevityharbor.com/en/watch/IzMM0dIitB4 Paul Robbins on Senescence, Senolytics & Extending Healthspan https://i.ytimg.com/vi/IzMM0dIitB4/hqdefault.jpg Dr. Paul Robbins, Professor at the University of Minnesota and Associate Director at the Masonic Institute on the Biology of Aging and Metabolism, explains how clearing senescent cells (with senolytics) can improve healthspan and possibly delay age-related diseases. He covers the latest research, mechanisms behind senescence, how NAD+ ties into it, and why aging itself is the main target. Chapters: 00:00 – Introduction 00:14 – What are Senescent Cells? 01:14 – What Are Senolytics? 02:09 – Why Paul Started Studying Aging 03:25 – The Goal: Healthspan, Not Just Lifespan 04:34 – Hallmarks of Aging and NAD+ 06:02 – Do NAD+ Supplements Work? 07:16 – Can We Measure Senescence in the Body? 08:16 – Senolytics in Clinical Use 09:09 – Diseases Being Targeted First 10:36 – Are Senolytics Safe? 12:03 – Will They Make Us Live to 150? 13:44 – Reducing Comorbidities Through Aging Research 15:02 – How Fast the Field Is Moving 16:16 – Why Most Anti-Aging Products Don’t Work 17:54 – Cultural Views on Aging 19:44 – Making Aging Interventions Fair and Equitable 21:44 – New Hallmarks of Aging 24:17 – How AI Helps Target Senescent Cells 25:54 – Distinguishing Senescent vs Inflammatory Cells 27:12 – Different Types of Senolytics 28:49 – Targeting Specific Cell Types 30:07 – Can We Vaccinate Against Aging? 31:34 – Personalized Approaches and Biomarkers 33:24 – Clinical Trials and What They Measure 34:40 – Lessons from Centenarians 35:01 – Final Thoughts #PaulRobbins #Senolytics #HealthyAging #NADplus #AgingResearch #CellularSenescence #Healthspan #Geroscience #UniversityOfMinnesota #AntiAging https://www.youtube-nocookie.com/embed/IzMM0dIitB4 2111 2025-05-31T18:47:45.000Z 2026-10-22T18:43:13.585Z https://longevityharbor.com/de/watch/IzMM0dIitB4 Paul Robbins on Senescence, Senolytics & Extending Healthspan https://i.ytimg.com/vi/IzMM0dIitB4/hqdefault.jpg Dr. Paul Robbins, Professor at the University of Minnesota and Associate Director at the Masonic Institute on the Biology of Aging and Metabolism, explains how clearing senescent cells (with senolytics) can improve healthspan and possibly delay age-related diseases. He covers the latest research, mechanisms behind senescence, how NAD+ ties into it, and why aging itself is the main target. Chapters: 00:00 – Introduction 00:14 – What are Senescent Cells? 01:14 – What Are Senolytics? 02:09 – Why Paul Started Studying Aging 03:25 – The Goal: Healthspan, Not Just Lifespan 04:34 – Hallmarks of Aging and NAD+ 06:02 – Do NAD+ Supplements Work? 07:16 – Can We Measure Senescence in the Body? 08:16 – Senolytics in Clinical Use 09:09 – Diseases Being Targeted First 10:36 – Are Senolytics Safe? 12:03 – Will They Make Us Live to 150? 13:44 – Reducing Comorbidities Through Aging Research 15:02 – How Fast the Field Is Moving 16:16 – Why Most Anti-Aging Products Don’t Work 17:54 – Cultural Views on Aging 19:44 – Making Aging Interventions Fair and Equitable 21:44 – New Hallmarks of Aging 24:17 – How AI Helps Target Senescent Cells 25:54 – Distinguishing Senescent vs Inflammatory Cells 27:12 – Different Types of Senolytics 28:49 – Targeting Specific Cell Types 30:07 – Can We Vaccinate Against Aging? 31:34 – Personalized Approaches and Biomarkers 33:24 – Clinical Trials and What They Measure 34:40 – Lessons from Centenarians 35:01 – Final Thoughts #PaulRobbins #Senolytics #HealthyAging #NADplus #AgingResearch #CellularSenescence #Healthspan #Geroscience #UniversityOfMinnesota #AntiAging https://www.youtube-nocookie.com/embed/IzMM0dIitB4 2111 2025-05-31T18:47:45.000Z 2026-10-22T18:43:13.585Z https://longevityharbor.com/en/watch/J-CYeaQQCHM Intermittent fasting video description: claimed metabolic and aging benefits https://i.ytimg.com/vi/J-CYeaQQCHM/hqdefault.jpg The description says research suggests strategic fasting periods may support weight management, insulin sensitivity, fat metabolism and metabolic health, and links them to healthier aging; it also says the approach does not work the same way for everyone. https://www.youtube-nocookie.com/embed/J-CYeaQQCHM 279 2026-06-05T13:12:53.000Z 2026-10-23T00:07:07.439Z https://longevityharbor.com/de/watch/J-CYeaQQCHM Video-Beschreibung zu Intervallfasten: behauptete Stoffwechsel- und Altersvorteile https://i.ytimg.com/vi/J-CYeaQQCHM/hqdefault.jpg Laut Beschreibung deutet Forschung darauf hin, dass gezielte Fastenphasen Gewichtsmanagement, Insulinempfindlichkeit, Fettstoffwechsel und Stoffwechselgesundheit unterstützen könnten, und sie verknüpft dies mit gesünderem Altern; zudem wirke die Methode nicht bei allen gleich. https://www.youtube-nocookie.com/embed/J-CYeaQQCHM 279 2026-06-05T13:12:53.000Z 2026-10-23T00:07:07.439Z https://longevityharbor.com/en/watch/J-iXFUiE0kg Video description: diet, inflammation and aging topics in Talking Heads https://i.ytimg.com/vi/J-iXFUiE0kg/hqdefault.jpg The description says host Red O’Laughlin explores how everyday food choices may affect energy, inflammation, cellular health and longevity, and lists topics such as the biology of aging, the microbiome and fasting protocols. https://www.youtube-nocookie.com/embed/J-iXFUiE0kg 2725 2026-09-04T05:35:37.000Z 2026-10-22T22:30:15.172Z https://longevityharbor.com/de/watch/J-iXFUiE0kg Videobeschreibung: Themen zu Ernährung, Entzündung und Altern bei Talking Heads https://i.ytimg.com/vi/J-iXFUiE0kg/hqdefault.jpg Laut Beschreibung untersucht Gastgeber Red O’Laughlin, wie alltägliche Ernährungsentscheidungen Energie, Entzündung, Zellgesundheit und Langlebigkeit beeinflussen könnten, und nennt Themen wie die Biologie des Alterns, das Mikrobiom und Fastenprotokolle. https://www.youtube-nocookie.com/embed/J-iXFUiE0kg 2725 2026-09-04T05:35:37.000Z 2026-10-22T22:30:15.172Z https://longevityharbor.com/en/watch/J2GjH_4iEhY Best Fasting Method for Long-Term Weight Loss (New Study) https://i.ytimg.com/vi/J2GjH_4iEhY/hqdefault.jpg Let's break down the latest study on the best fasting for weight loss! 🥗 Amplify Intermittent Fasting: https://www.youtube.com/watch?v=Ty4sHiU0TDk&list=PLq4OOzo28fwy9JL3gVuAhps1ZTwWeUAx1&index=5 The end of the year is looming by and everyone (as usual) is talking about losing weight. But to do that you have to get into calorie deficit... in other terms fast a little. But which fasting method is the best for weight loss? Is it alternate day fasting (ADF), short-term fasting (STF), time-restricted eating (TRE) or continuous energy restriction (CER) ? Let's break down the latest meta analysis and find out the pros and cons of each method, because truth to be told EACH ONE CAN WORK when you know how to use them or even better - combine different approaches for the best results. Comparing caloric restriction regimens for effective weight management in adults: a systematic review and network meta-analysis: https://pubmed.ncbi.nlm.nih.gov/39327619/ 00:00 The Best Way to Lose and Maintain Weight 00:31 Why Calorie Restriction Matters 01:14 The Science of Nutrient-Sensing Pathways 02:17 Fasting Methods and Their Benefits 04:15 Short-Term Weight Loss: Pros and Cons 06:56 Long-Term Challenges and Lean Mass Preservation 08:10 Sustainability of Weight Loss 10:09 What I Do Now 12:36 Key Takeaways for Sustainable Weight Management 𝐒𝐩𝐞𝐜𝐢𝐚𝐥 𝐍𝐨𝐭𝐞: Hi! This channel is all about sharing helpful stuff, thanks to awesome people like you. If you learned something cool, pass it along to your friends! It’s an easy way to help them out, support me, and keep us all focused on living well for the long haul! 🖖 ---------------------------------------------------------------------------------------------------------------------- "Living is Smart" is designed around the idea that we all have a good chance to live to and past 100 by doing these two things: 1) Small, 80/20 (easy, but smart) consistent lifestyle changes and 2) Banding together to support each other and to cause ripple through scientific and political scene https://www.youtube-nocookie.com/embed/J2GjH_4iEhY 828 2024-12-15T03:34:01.000Z 2026-10-22T19:54:18.349Z https://longevityharbor.com/de/watch/J2GjH_4iEhY Best Fasting Method for Long-Term Weight Loss (New Study) https://i.ytimg.com/vi/J2GjH_4iEhY/hqdefault.jpg Let's break down the latest study on the best fasting for weight loss! 🥗 Amplify Intermittent Fasting: https://www.youtube.com/watch?v=Ty4sHiU0TDk&list=PLq4OOzo28fwy9JL3gVuAhps1ZTwWeUAx1&index=5 The end of the year is looming by and everyone (as usual) is talking about losing weight. But to do that you have to get into calorie deficit... in other terms fast a little. But which fasting method is the best for weight loss? Is it alternate day fasting (ADF), short-term fasting (STF), time-restricted eating (TRE) or continuous energy restriction (CER) ? Let's break down the latest meta analysis and find out the pros and cons of each method, because truth to be told EACH ONE CAN WORK when you know how to use them or even better - combine different approaches for the best results. Comparing caloric restriction regimens for effective weight management in adults: a systematic review and network meta-analysis: https://pubmed.ncbi.nlm.nih.gov/39327619/ 00:00 The Best Way to Lose and Maintain Weight 00:31 Why Calorie Restriction Matters 01:14 The Science of Nutrient-Sensing Pathways 02:17 Fasting Methods and Their Benefits 04:15 Short-Term Weight Loss: Pros and Cons 06:56 Long-Term Challenges and Lean Mass Preservation 08:10 Sustainability of Weight Loss 10:09 What I Do Now 12:36 Key Takeaways for Sustainable Weight Management 𝐒𝐩𝐞𝐜𝐢𝐚𝐥 𝐍𝐨𝐭𝐞: Hi! This channel is all about sharing helpful stuff, thanks to awesome people like you. If you learned something cool, pass it along to your friends! It’s an easy way to help them out, support me, and keep us all focused on living well for the long haul! 🖖 ---------------------------------------------------------------------------------------------------------------------- "Living is Smart" is designed around the idea that we all have a good chance to live to and past 100 by doing these two things: 1) Small, 80/20 (easy, but smart) consistent lifestyle changes and 2) Banding together to support each other and to cause ripple through scientific and political scene https://www.youtube-nocookie.com/embed/J2GjH_4iEhY 828 2024-12-15T03:34:01.000Z 2026-10-22T19:54:18.349Z https://longevityharbor.com/en/watch/J2yr6fIe-Jo 3: Neuronal Senescence in Dorsal Root Ganglia and Pain https://i.ytimg.com/vi/J2yr6fIe-Jo/hqdefault.jpg This scientific paper explores the phenomenon of neuronal senescence in the dorsal root ganglia (DRG), which are clusters of nerve cells involved in sensory perception. The research demonstrates that aging and peripheral nerve injury both contribute to the accumulation of senescent neurons in the DRG of mice and humans. These senescent neurons are found to express pro-inflammatory markers like IL6 and exhibit altered electrical excitability, particularly in nociceptors, which are pain-sensing neurons. Crucially, the study shows that targeting and removing these senescent cells with a senolytic drug can improve pain-related behaviors, suggesting a potential therapeutic avenue for treating chronic pain, especially in older individuals. Donovan, L.J., Brewer, C.L., Bond, S.F. et al. Aging and injury drive neuronal senescence in the dorsal root ganglia. Nat Neurosci 28, 985–997 (2025). https://doi.org/10.1038/s41593-025-01954-x Follow Dr. Anthony Novello, PT, DPT ⁠⁠@anthonynovello.dpt (https://www.instagram.com/anthonynovello.dpt/) https://www.youtube-nocookie.com/embed/J2yr6fIe-Jo 1387 2025-06-07T21:41:32.000Z 2026-10-22T19:43:47.685Z https://longevityharbor.com/de/watch/J2yr6fIe-Jo 3: Neuronal Senescence in Dorsal Root Ganglia and Pain https://i.ytimg.com/vi/J2yr6fIe-Jo/hqdefault.jpg This scientific paper explores the phenomenon of neuronal senescence in the dorsal root ganglia (DRG), which are clusters of nerve cells involved in sensory perception. The research demonstrates that aging and peripheral nerve injury both contribute to the accumulation of senescent neurons in the DRG of mice and humans. These senescent neurons are found to express pro-inflammatory markers like IL6 and exhibit altered electrical excitability, particularly in nociceptors, which are pain-sensing neurons. Crucially, the study shows that targeting and removing these senescent cells with a senolytic drug can improve pain-related behaviors, suggesting a potential therapeutic avenue for treating chronic pain, especially in older individuals. Donovan, L.J., Brewer, C.L., Bond, S.F. et al. Aging and injury drive neuronal senescence in the dorsal root ganglia. Nat Neurosci 28, 985–997 (2025). https://doi.org/10.1038/s41593-025-01954-x Follow Dr. Anthony Novello, PT, DPT ⁠⁠@anthonynovello.dpt (https://www.instagram.com/anthonynovello.dpt/) https://www.youtube-nocookie.com/embed/J2yr6fIe-Jo 1387 2025-06-07T21:41:32.000Z 2026-10-22T19:43:47.685Z https://longevityharbor.com/en/watch/J35kHj1IUJs AVEA CEO describes pairing NMN with a NAD+ Booster in a supplement bundle https://i.ytimg.com/vi/J35kHj1IUJs/hqdefault.jpg In this video description, AVEA's CEO argues that NMN, a precursor the body converts to NAD+, works better alongside the company's NAD+ Booster; he cites an AVEA study in which 80% of participants felt more energetic within three months. https://www.youtube-nocookie.com/embed/J35kHj1IUJs 98 2026-08-13T15:00:18.000Z 2026-10-22T23:05:46.698Z https://longevityharbor.com/de/watch/J35kHj1IUJs AVEA-CEO beschreibt Kombination von NMN mit einem NAD+-Booster in einem Supplement-Bundle https://i.ytimg.com/vi/J35kHj1IUJs/hqdefault.jpg In dieser Videobeschreibung argumentiert der CEO von AVEA, dass NMN, eine Vorstufe, die der Körper zu NAD+ umwandelt, zusammen mit dem NAD+-Booster des Unternehmens besser wirke; er nennt eine AVEA-Studie, in der sich 80% der Teilnehmenden innerhalb von drei Monaten energiereicher fühlten. https://www.youtube-nocookie.com/embed/J35kHj1IUJs 98 2026-08-13T15:00:18.000Z 2026-10-22T23:05:46.698Z https://longevityharbor.com/en/watch/J3P4xbySRiw Protein intake and muscle strength after 60: a video description overview https://i.ytimg.com/vi/J3P4xbySRiw/hqdefault.jpg The description says enough protein alone may not preserve muscle mass and strength after 60; it names protein quality, leucine, distribution across the day and strength training as discussed factors. https://www.youtube-nocookie.com/embed/J3P4xbySRiw 695 2026-10-05T16:01:37.000Z 2026-10-22T21:20:42.282Z https://longevityharbor.com/de/watch/J3P4xbySRiw Eiweißzufuhr und Muskelkraft ab 60: ein Überblick aus der Videobeschreibung https://i.ytimg.com/vi/J3P4xbySRiw/hqdefault.jpg Laut Beschreibung reicht ausreichend Eiweiß allein womöglich nicht, um Muskelmasse und Kraft ab 60 zu erhalten; genannt werden Proteinqualität, Leucin, Verteilung über den Tag und Krafttraining als besprochene Faktoren. https://www.youtube-nocookie.com/embed/J3P4xbySRiw 695 2026-10-05T16:01:37.000Z 2026-10-22T21:20:42.282Z https://longevityharbor.com/en/watch/J3uR7EEIkFs Ab 60: Dieses eine Frühstückslebensmittel unterstützt den Muskelerhalt und mehr Kraft! https://i.ytimg.com/vi/J3uR7EEIkFs/hqdefault.jpg Fühlen Sie sich nach dem 60. Lebensjahr schwächer? Werden Treppensteigen, längeres Gehen oder das Aufstehen vom Stuhl zunehmend schwieriger? Dahinter kann unter anderem ein altersbedingter Muskelabbau stecken, der auch als Sarkopenie bezeichnet wird. In diesem Video erfahren Sie, wie ein einfaches und preiswertes Lebensmittel – das ganze Ei – dazu beitragen kann, eine ausgewogene, proteinreiche Ernährung im Alter zu unterstützen. Wir erklären, warum Eiweiß mit zunehmendem Alter besonders wichtig wird, was hinter der sogenannten anabolen Resistenz steckt und welche Rolle essenzielle Aminosäuren wie Leucin beim Erhalt der Muskelmasse spielen. 🥚 DAS ERFAHREN SIE IN DIESEM VIDEO: ✅ Warum Muskelkraft und Beweglichkeit ab 60 nachlassen können ✅ Was Sarkopenie und altersbedingter Muskelabbau bedeuten ✅ Warum viele Menschen zum Frühstück zu wenig Eiweiß aufnehmen ✅ Wie Eier hochwertiges Protein und essenzielle Aminosäuren liefern ✅ Welche Nährstoffe im Eigelb stecken, darunter Cholin, Vitamin B12 und Selen ✅ Was Sie über Eier, Cholesterin und eine ausgewogene Ernährung wissen sollten ✅ Warum zwei Eier allein möglicherweise nicht ausreichen, um den individuellen Eiweißbedarf zu decken ✅ Wie Sie Eier mit griechischem Joghurt, Milch, Nüssen, Samen oder anderen eiweißreichen Lebensmitteln kombinieren können ✅ Warum regelmäßige Bewegung und Krafttraining für den Muskelerhalt entscheidend sind ✅ Wie Sie ein einfaches, proteinreiches Frühstück in Ihren Alltag integrieren können DIE EINFACHE 3-SCHRITTE-ROUTINE: 1️⃣ Integrieren Sie ganze Eier in ein ausgewogenes Frühstück. 2️⃣ Ergänzen Sie weitere proteinreiche Lebensmittel, um Ihren individuellen Eiweißbedarf besser zu decken. 3️⃣ Bleiben Sie regelmäßig in Bewegung und führen Sie geeignete Kraftübungen durch, sofern Ihr Gesundheitszustand dies zulässt. Wichtig: Eier sind kein Wundermittel. Kein einzelnes Lebensmittel kann Muskelabbau zuverlässig verhindern oder eine Sarkopenie allein rückgängig machen. Eine bedarfsgerechte Eiweißzufuhr, regelmäßiges Krafttraining, ausreic https://www.youtube-nocookie.com/embed/J3uR7EEIkFs 982 2026-10-11T07:00:37.000Z 2026-10-22T20:11:49.301Z https://longevityharbor.com/de/watch/J3uR7EEIkFs Ab 60: Dieses eine Frühstückslebensmittel unterstützt den Muskelerhalt und mehr Kraft! https://i.ytimg.com/vi/J3uR7EEIkFs/hqdefault.jpg Fühlen Sie sich nach dem 60. Lebensjahr schwächer? Werden Treppensteigen, längeres Gehen oder das Aufstehen vom Stuhl zunehmend schwieriger? Dahinter kann unter anderem ein altersbedingter Muskelabbau stecken, der auch als Sarkopenie bezeichnet wird. In diesem Video erfahren Sie, wie ein einfaches und preiswertes Lebensmittel – das ganze Ei – dazu beitragen kann, eine ausgewogene, proteinreiche Ernährung im Alter zu unterstützen. Wir erklären, warum Eiweiß mit zunehmendem Alter besonders wichtig wird, was hinter der sogenannten anabolen Resistenz steckt und welche Rolle essenzielle Aminosäuren wie Leucin beim Erhalt der Muskelmasse spielen. 🥚 DAS ERFAHREN SIE IN DIESEM VIDEO: ✅ Warum Muskelkraft und Beweglichkeit ab 60 nachlassen können ✅ Was Sarkopenie und altersbedingter Muskelabbau bedeuten ✅ Warum viele Menschen zum Frühstück zu wenig Eiweiß aufnehmen ✅ Wie Eier hochwertiges Protein und essenzielle Aminosäuren liefern ✅ Welche Nährstoffe im Eigelb stecken, darunter Cholin, Vitamin B12 und Selen ✅ Was Sie über Eier, Cholesterin und eine ausgewogene Ernährung wissen sollten ✅ Warum zwei Eier allein möglicherweise nicht ausreichen, um den individuellen Eiweißbedarf zu decken ✅ Wie Sie Eier mit griechischem Joghurt, Milch, Nüssen, Samen oder anderen eiweißreichen Lebensmitteln kombinieren können ✅ Warum regelmäßige Bewegung und Krafttraining für den Muskelerhalt entscheidend sind ✅ Wie Sie ein einfaches, proteinreiches Frühstück in Ihren Alltag integrieren können DIE EINFACHE 3-SCHRITTE-ROUTINE: 1️⃣ Integrieren Sie ganze Eier in ein ausgewogenes Frühstück. 2️⃣ Ergänzen Sie weitere proteinreiche Lebensmittel, um Ihren individuellen Eiweißbedarf besser zu decken. 3️⃣ Bleiben Sie regelmäßig in Bewegung und führen Sie geeignete Kraftübungen durch, sofern Ihr Gesundheitszustand dies zulässt. Wichtig: Eier sind kein Wundermittel. Kein einzelnes Lebensmittel kann Muskelabbau zuverlässig verhindern oder eine Sarkopenie allein rückgängig machen. Eine bedarfsgerechte Eiweißzufuhr, regelmäßiges Krafttraining, ausreic https://www.youtube-nocookie.com/embed/J3uR7EEIkFs 982 2026-10-11T07:00:37.000Z 2026-10-22T20:11:49.301Z https://longevityharbor.com/en/watch/J4oxaNpcz5M Rapamycin: The Longevity Drug? Unpacking the Science of Anti-Aging https://i.ytimg.com/vi/J4oxaNpcz5M/hqdefault.jpg Join us for an in-depth exploration of Rapamycin, a fascinating compound discovered on Easter Island that's now at the forefront of longevity research! In this comprehensive podcast episode, we break down the science behind this powerful molecule and its potential to mimic the anti-aging effects of calorie restriction. We'll cover: Rapamycin's Origins & Uses: Discover its unique discovery from Streptomyces hygroscopicus on Rapa Nui, its chemical properties, and its established medical applications as an immunosuppressant for organ transplants, and treatments for rare diseases like LAM and PEComa.   The Power of Calorie Restriction (CR): Understand why CR has been a foundational strategy in longevity research for decades, showing remarkable healthspan and lifespan extension in diverse animal models, including Rhesus Monkeys, and the challenges of its human adherence.   The mTOR Pathway Explained: Dive into the central role of the mTOR pathway as a master regulator of cell growth, metabolism, and aging. Learn about mTORC1 (anabolic processes, autophagy inhibition) and mTORC2 (glucose/lipid metabolism), and how rapamycin specifically targets these complexes.   Rapamycin as a CR Mimetic: Shared Benefits: Explore the significant overlap in effects, including robust lifespan extension across species (from yeast to mammals) , and the crucial induction of autophagy for cellular recycling and repair.   Key Differences: Understand how rapamycin and CR can operate through distinct molecular pathways, leading to additive benefits when combined, and their differing impacts on body weight and glucose levels.   Evidence from Preclinical Models: We review the compelling data on rapamycin's ability to extend lifespan and delay age-related diseases like cardiovascular decline, neurodegeneration, and cancer in various animal models, while also discussing important considerations like sex differences in response.   Translating to Humans: Learn about the current landscape of human clinical trials, focusing on healthspa https://www.youtube-nocookie.com/embed/J4oxaNpcz5M 370 2025-07-06T05:30:26.000Z 2026-10-22T19:54:22.251Z https://longevityharbor.com/de/watch/J4oxaNpcz5M Rapamycin: The Longevity Drug? Unpacking the Science of Anti-Aging https://i.ytimg.com/vi/J4oxaNpcz5M/hqdefault.jpg Join us for an in-depth exploration of Rapamycin, a fascinating compound discovered on Easter Island that's now at the forefront of longevity research! In this comprehensive podcast episode, we break down the science behind this powerful molecule and its potential to mimic the anti-aging effects of calorie restriction. We'll cover: Rapamycin's Origins & Uses: Discover its unique discovery from Streptomyces hygroscopicus on Rapa Nui, its chemical properties, and its established medical applications as an immunosuppressant for organ transplants, and treatments for rare diseases like LAM and PEComa.   The Power of Calorie Restriction (CR): Understand why CR has been a foundational strategy in longevity research for decades, showing remarkable healthspan and lifespan extension in diverse animal models, including Rhesus Monkeys, and the challenges of its human adherence.   The mTOR Pathway Explained: Dive into the central role of the mTOR pathway as a master regulator of cell growth, metabolism, and aging. Learn about mTORC1 (anabolic processes, autophagy inhibition) and mTORC2 (glucose/lipid metabolism), and how rapamycin specifically targets these complexes.   Rapamycin as a CR Mimetic: Shared Benefits: Explore the significant overlap in effects, including robust lifespan extension across species (from yeast to mammals) , and the crucial induction of autophagy for cellular recycling and repair.   Key Differences: Understand how rapamycin and CR can operate through distinct molecular pathways, leading to additive benefits when combined, and their differing impacts on body weight and glucose levels.   Evidence from Preclinical Models: We review the compelling data on rapamycin's ability to extend lifespan and delay age-related diseases like cardiovascular decline, neurodegeneration, and cancer in various animal models, while also discussing important considerations like sex differences in response.   Translating to Humans: Learn about the current landscape of human clinical trials, focusing on healthspa https://www.youtube-nocookie.com/embed/J4oxaNpcz5M 370 2025-07-06T05:30:26.000Z 2026-10-22T19:54:22.251Z https://longevityharbor.com/en/watch/J5fB6pPTuzo Why 16 Hours Isn't Enough for True Fasting Benefits, with Dr. Chris Rhodes https://i.ytimg.com/vi/J5fB6pPTuzo/hqdefault.jpg What you know about fasting might be wrong! Or, at least, inaccurate. You might believe a 16-hour fast unlocks those deep, cellular-level benefits. As it turns out, that's not actually how your body works. That layer of metabolic magic happens in longer fasts, but most people never get there. However, there's a way to get many of the benefits without being hungry! In this episode, Dr. Chris Rhodes, a nutritional biochemist known for his research into fasting, nutrition, and longevity, unpacks why the typical 16-hour fast doesn't quite reach the deeper benefits like autophagy or a metabolic reset, and how to achieve it with less effort. Listen now and start fasting towards health! For show notes, visit https://fivejourneys.com/podcasts/fast-for-longevity/ Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/ Related Episodes: Leverage Ketosis and Fasting to Reverse Disease, with Ben Azadi (https://fivejourneys.com/podcasts/leverage-ketosis-and-fasting-to-reverse-disease/) Reverse Pre-Diabetes with a Fasting-Mimicking Diet, with Dr. Joseph Antoun (https://fivejourneys.com/podcasts/reverse-pre-diabetes-with-a-fasting-mimicking-diet/) Unlocking Longevity: Transform Your Health with a Fasting Mimicking Diet, with Dr. Joseph Antoun (https://fivejourneys.com/podcasts/unlocking-longevity-transform-your-health-with-a-fasting-mimicking-diet/) Try Keto for Optimal Health, with Robert & Crystal Sikes (https://fivejourneys.com/podcasts/try-keto-for-optimal-health/) https://www.youtube-nocookie.com/embed/J5fB6pPTuzo 1753 2025-08-18T10:50:30.000Z 2026-10-22T18:54:08.127Z https://longevityharbor.com/de/watch/J5fB6pPTuzo Why 16 Hours Isn't Enough for True Fasting Benefits, with Dr. Chris Rhodes https://i.ytimg.com/vi/J5fB6pPTuzo/hqdefault.jpg What you know about fasting might be wrong! Or, at least, inaccurate. You might believe a 16-hour fast unlocks those deep, cellular-level benefits. As it turns out, that's not actually how your body works. That layer of metabolic magic happens in longer fasts, but most people never get there. However, there's a way to get many of the benefits without being hungry! In this episode, Dr. Chris Rhodes, a nutritional biochemist known for his research into fasting, nutrition, and longevity, unpacks why the typical 16-hour fast doesn't quite reach the deeper benefits like autophagy or a metabolic reset, and how to achieve it with less effort. Listen now and start fasting towards health! For show notes, visit https://fivejourneys.com/podcasts/fast-for-longevity/ Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/ Related Episodes: Leverage Ketosis and Fasting to Reverse Disease, with Ben Azadi (https://fivejourneys.com/podcasts/leverage-ketosis-and-fasting-to-reverse-disease/) Reverse Pre-Diabetes with a Fasting-Mimicking Diet, with Dr. Joseph Antoun (https://fivejourneys.com/podcasts/reverse-pre-diabetes-with-a-fasting-mimicking-diet/) Unlocking Longevity: Transform Your Health with a Fasting Mimicking Diet, with Dr. Joseph Antoun (https://fivejourneys.com/podcasts/unlocking-longevity-transform-your-health-with-a-fasting-mimicking-diet/) Try Keto for Optimal Health, with Robert & Crystal Sikes (https://fivejourneys.com/podcasts/try-keto-for-optimal-health/) https://www.youtube-nocookie.com/embed/J5fB6pPTuzo 1753 2025-08-18T10:50:30.000Z 2026-10-22T18:54:08.127Z https://longevityharbor.com/en/watch/J6a7nLcos1U Dr. David Sinclair's Research on NMN, Resveratrol, and The Secret to Longevity https://i.ytimg.com/vi/J6a7nLcos1U/hqdefault.jpg Disclaimer: The information provided in this video is for general informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before making any changes to your diet, exercise routine, or lifestyle. The creator of this video does not assume any liability from the use of this information. Citations: [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC9289528/ [2] https://www.webmd.com/diet/health-benefits-resveratrol [3] https://www.youtube.com/watch?v=bRWT7hVgwuM [4] https://www.nmn.com/news/nmn-resveratrol-ginsenosides-nad [5] https://www.nature.com/articles/s41698-017-0038-6 [6] https://www.youtube.com/watch?v=yWx77ARQ9lo [7] https://pmc.ncbi.nlm.nih.gov/articles/PMC7238909/ [8] https://pmc.ncbi.nlm.nih.gov/articles/PMC6164842/ [9] https://www.youtube.com/watch?v=5DtWqzalEnc https://www.youtube-nocookie.com/embed/J6a7nLcos1U 276 2025-03-15T18:02:13.000Z 2026-10-22T19:32:38.608Z https://longevityharbor.com/de/watch/J6a7nLcos1U Dr. David Sinclair's Research on NMN, Resveratrol, and The Secret to Longevity https://i.ytimg.com/vi/J6a7nLcos1U/hqdefault.jpg Disclaimer: The information provided in this video is for general informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before making any changes to your diet, exercise routine, or lifestyle. The creator of this video does not assume any liability from the use of this information. Citations: [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC9289528/ [2] https://www.webmd.com/diet/health-benefits-resveratrol [3] https://www.youtube.com/watch?v=bRWT7hVgwuM [4] https://www.nmn.com/news/nmn-resveratrol-ginsenosides-nad [5] https://www.nature.com/articles/s41698-017-0038-6 [6] https://www.youtube.com/watch?v=yWx77ARQ9lo [7] https://pmc.ncbi.nlm.nih.gov/articles/PMC7238909/ [8] https://pmc.ncbi.nlm.nih.gov/articles/PMC6164842/ [9] https://www.youtube.com/watch?v=5DtWqzalEnc https://www.youtube-nocookie.com/embed/J6a7nLcos1U 276 2025-03-15T18:02:13.000Z 2026-10-22T19:32:38.608Z https://longevityharbor.com/en/watch/J8IxCGaJP_M New method makes epigenetic aging clocks accurate and easier to interpret https://i.ytimg.com/vi/J8IxCGaJP_M/hqdefault.jpg New method makes epigenetic aging clocks accurate and easier to interpret https://www.youtube-nocookie.com/embed/J8IxCGaJP_M 205 2026-07-19T09:35:10.000Z 2026-10-22T19:21:27.746Z https://longevityharbor.com/de/watch/J8IxCGaJP_M New method makes epigenetic aging clocks accurate and easier to interpret https://i.ytimg.com/vi/J8IxCGaJP_M/hqdefault.jpg New method makes epigenetic aging clocks accurate and easier to interpret https://www.youtube-nocookie.com/embed/J8IxCGaJP_M 205 2026-07-19T09:35:10.000Z 2026-10-22T19:21:27.746Z https://longevityharbor.com/en/watch/J8KKqgfcOWg Video description: five training topics from creatine to knee osteoarthritis https://i.ytimg.com/vi/J8KKqgfcOWg/hqdefault.jpg The description says the episode covers five new findings on creatine, eccentric training, cardio plus strength training, balance with aging, and resistance training intensity in knee osteoarthritis. No results are given. https://www.youtube-nocookie.com/embed/J8KKqgfcOWg 196 2026-10-03T13:10:42.000Z 2026-10-22T21:29:01.323Z https://longevityharbor.com/de/watch/J8KKqgfcOWg Videobeschreibung: fünf Trainingsthemen von Kreatin bis Knie-Arthrose https://i.ytimg.com/vi/J8KKqgfcOWg/hqdefault.jpg Laut Beschreibung behandelt die Folge fünf neue Befunde zu Kreatin, exzentrischem Training, Ausdauer plus Krafttraining, Gleichgewicht im Alter und Krafttrainingsintensität bei Knie-Arthrose. Ergebnisse werden nicht genannt. https://www.youtube-nocookie.com/embed/J8KKqgfcOWg 196 2026-10-03T13:10:42.000Z 2026-10-22T21:29:01.323Z https://longevityharbor.com/en/watch/J9XmI7Q2XhM GlyNAC video description links glutathione deficiency to aging decline https://i.ytimg.com/vi/J9XmI7Q2XhM/hqdefault.jpg The description says research identifies glutathione deficiency, mitochondrial dysfunction and oxidative stress as drivers of physical and cognitive decline in aging populations, and that clinical trials show GlyNAC restores cellular antioxidant levels and improves energy metabolism. https://www.youtube-nocookie.com/embed/J9XmI7Q2XhM 416 2026-01-24T18:00:29.000Z 2026-10-23T02:46:40.254Z https://longevityharbor.com/de/watch/J9XmI7Q2XhM GlyNAC-Videobeschreibung verknüpft Glutathionmangel mit Altersabbau https://i.ytimg.com/vi/J9XmI7Q2XhM/hqdefault.jpg Laut Beschreibung nennt die Forschung Glutathionmangel, mitochondriale Dysfunktion und oxidativen Stress als Treiber körperlichen und kognitiven Abbaus in alternden Populationen; klinische Studien zeigten, dass GlyNAC zelluläre Antioxidantienwerte wiederherstellt und den Energiestoffwechsel verbessert. https://www.youtube-nocookie.com/embed/J9XmI7Q2XhM 416 2026-01-24T18:00:29.000Z 2026-10-23T02:46:40.254Z https://longevityharbor.com/en/watch/JCTb3QSrGMQ Anti-Aging Expert: Missing This Vitamin Is Like Smoking! The Truth About Creatine! - Rhonda Patrick https://i.ytimg.com/vi/JCTb3QSrGMQ/hqdefault.jpg Anti-aging expert Dr Rhonda Patrick reveals how magnesium, HIIT workouts, creatine, and vitamin D can prevent disease, slow aging, and boost brain power - starting today. Dr. Rhonda Patrick is a PhD biomedical scientist, expert in aging, nutrition, and metabolism, and founder of FoundMyFitness. She produces a monthly series of in-depth, science-focused podcasts exploring actionable strategies for enhancing longevity, cognitive performance, and physical health. She explains: ▫️Why cardiovascular fitness is the #1 predictor of lifespan ▫️The groundbreaking science behind rejuvenating your heart by 20 years ▫️How small daily habits can cut your risk of Alzheimer’s and cancer ▫️The hidden link between mitochondrial health, aging, and chronic disease ⏱ Timestamps: 00:00 Intro 02:04 My Mission to Improve People's Health 03:37 What Impact Will Rhonda's Research Have on People? 05:09 The Role of Genetics in Aging vs. Lifestyle 09:53 The Future of Aging, Longevity, and Gene Therapy 15:15 Death-Related Risks of Being Sedentary 22:17 How to Improve Your Cardiorespiratory Fitness 25:32 Best Workout Routine to Improve Cardio Health 30:01 Norwegian 4x4 Training Explained 32:28 How the Body Generates Energy and Exercise Intensity 38:14 Why We Can’t Drink Lactate and the Impact of Vigorous Training 41:09 Decline in Production of Lactate, Creatine, and Other Key Substances 42:20 How to Reduce Cognitive Decline 46:58 What Causes Dementia and Alzheimer’s 52:56 Do Multivitamins Improve Cognitive Performance? 01:00:13 70% of the U.S. Population Is Vitamin D Deficient 01:02:59 Vitamin D Deficiency and Increased Risk of Dementia 01:06:49 Views on the Ketogenic Diet 01:09:39 What Is Ketosis? 01:14:28 How the Keto Diet Affects Life Expectancy 01:19:30 Exogenous Ketones and Cognitive Repair 01:23:53 Recommended Superfoods 01:26:33 Omega-3: Effects on Mental Health, Depression, and Longevity 01:32:08 Is Omega-3 Supplementation the Same as a High Omega-3 Diet? 01:35:12 Ads 01:36:09 Crea https://www.youtube-nocookie.com/embed/JCTb3QSrGMQ 10729 2025-07-28T07:00:24.000Z 2026-10-22T18:43:11.776Z https://longevityharbor.com/de/watch/JCTb3QSrGMQ Anti-Aging Expert: Missing This Vitamin Is Like Smoking! The Truth About Creatine! - Rhonda Patrick https://i.ytimg.com/vi/JCTb3QSrGMQ/hqdefault.jpg Anti-aging expert Dr Rhonda Patrick reveals how magnesium, HIIT workouts, creatine, and vitamin D can prevent disease, slow aging, and boost brain power - starting today. Dr. Rhonda Patrick is a PhD biomedical scientist, expert in aging, nutrition, and metabolism, and founder of FoundMyFitness. She produces a monthly series of in-depth, science-focused podcasts exploring actionable strategies for enhancing longevity, cognitive performance, and physical health. She explains: ▫️Why cardiovascular fitness is the #1 predictor of lifespan ▫️The groundbreaking science behind rejuvenating your heart by 20 years ▫️How small daily habits can cut your risk of Alzheimer’s and cancer ▫️The hidden link between mitochondrial health, aging, and chronic disease ⏱ Timestamps: 00:00 Intro 02:04 My Mission to Improve People's Health 03:37 What Impact Will Rhonda's Research Have on People? 05:09 The Role of Genetics in Aging vs. Lifestyle 09:53 The Future of Aging, Longevity, and Gene Therapy 15:15 Death-Related Risks of Being Sedentary 22:17 How to Improve Your Cardiorespiratory Fitness 25:32 Best Workout Routine to Improve Cardio Health 30:01 Norwegian 4x4 Training Explained 32:28 How the Body Generates Energy and Exercise Intensity 38:14 Why We Can’t Drink Lactate and the Impact of Vigorous Training 41:09 Decline in Production of Lactate, Creatine, and Other Key Substances 42:20 How to Reduce Cognitive Decline 46:58 What Causes Dementia and Alzheimer’s 52:56 Do Multivitamins Improve Cognitive Performance? 01:00:13 70% of the U.S. Population Is Vitamin D Deficient 01:02:59 Vitamin D Deficiency and Increased Risk of Dementia 01:06:49 Views on the Ketogenic Diet 01:09:39 What Is Ketosis? 01:14:28 How the Keto Diet Affects Life Expectancy 01:19:30 Exogenous Ketones and Cognitive Repair 01:23:53 Recommended Superfoods 01:26:33 Omega-3: Effects on Mental Health, Depression, and Longevity 01:32:08 Is Omega-3 Supplementation the Same as a High Omega-3 Diet? 01:35:12 Ads 01:36:09 Crea https://www.youtube-nocookie.com/embed/JCTb3QSrGMQ 10729 2025-07-28T07:00:24.000Z 2026-10-22T18:43:11.776Z https://longevityharbor.com/en/watch/JDb45FPDH8o Video description: frailty, movement and bone signalling with Dr Vonda Wright https://i.ytimg.com/vi/JDb45FPDH8o/hqdefault.jpg In the description, Dr Vonda Wright says frailty is not an automatic part of aging and that moving the body you have, such as walking on land, in a warm pool or around the kitchen table, can change your trajectory. She also describes bone as releasing osteocalcin and links osteoporosis to dementia. https://www.youtube-nocookie.com/embed/JDb45FPDH8o 543 2026-02-22T11:00:24.000Z 2026-10-23T02:27:26.687Z https://longevityharbor.com/de/watch/JDb45FPDH8o Videobeschreibung: Gebrechlichkeit, Bewegung und Knochensignale mit Dr. Vonda Wright https://i.ytimg.com/vi/JDb45FPDH8o/hqdefault.jpg In der Beschreibung sagt Dr. Vonda Wright, Gebrechlichkeit sei kein automatischer Teil des Alterns, und Bewegung mit dem Körper, den man hat – etwa zu Fuß, in einem warmen Becken oder um den Küchentisch – könne die eigene Entwicklung verändern. Außerdem beschreibt sie Knochen, der Osteocalcin freisetzt, und verknüpft Osteoporose mit Demenz. https://www.youtube-nocookie.com/embed/JDb45FPDH8o 543 2026-02-22T11:00:24.000Z 2026-10-23T02:27:26.687Z https://longevityharbor.com/en/watch/JDww0LJMK-k LinAge2 claimed as biological aging clock with actionable biomarkers https://i.ytimg.com/vi/JDww0LJMK-k/hqdefault.jpg The description presents LinAge2 as a biological aging clock that, unlike epigenetic clocks, is said to offer actionable insights based on validated biomarkers. No data or validation details are given. https://www.youtube-nocookie.com/embed/JDww0LJMK-k 126 2026-05-31T18:06:57.000Z 2026-10-23T00:12:43.669Z https://longevityharbor.com/de/watch/JDww0LJMK-k LinAge2 als biologische Altersuhr mit nutzbaren Biomarkern beworben https://i.ytimg.com/vi/JDww0LJMK-k/hqdefault.jpg Die Beschreibung stellt LinAge2 als biologische Altersuhr dar, die anders als epigenetische Uhren angeblich nutzbare Einsichten aus validierten Biomarkern liefert. Daten oder Validierungsdetails fehlen. https://www.youtube-nocookie.com/embed/JDww0LJMK-k 126 2026-05-31T18:06:57.000Z 2026-10-23T00:12:43.669Z https://longevityharbor.com/en/watch/JJnKX571inc Podcast description: Sinclair discusses hallmarks of aging and slowing cellular aging https://i.ytimg.com/vi/JJnKX571inc/hqdefault.jpg The description says Sinclair and LaPlante discuss why we age, hallmarks such as mitochondrial dysfunction and stem cell exhaustion, and strategies like exercise, cold exposure and molecules including metformin; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/JJnKX571inc 1841 2026-09-04T16:35:09.000Z 2026-10-22T22:29:57.888Z https://longevityharbor.com/de/watch/JJnKX571inc Podcast-Beschreibung: Sinclair über Hallmarks des Alterns und Verlangsamung der Zellalterung https://i.ytimg.com/vi/JJnKX571inc/hqdefault.jpg Laut Beschreibung besprechen Sinclair und LaPlante, warum wir altern, Hallmarks wie mitochondriale Dysfunktion und Stammzellerschöpfung sowie Strategien wie Bewegung, Kälteexposition und Moleküle wie Metformin; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/JJnKX571inc 1841 2026-09-04T16:35:09.000Z 2026-10-22T22:29:57.888Z https://longevityharbor.com/en/watch/JZRa6XXkTbQ VERGISS KNIEBEUGEN! Diese 1 Übung verdoppelt sofort die Beinkraft! | Ohne Fitnessstudio! https://i.ytimg.com/vi/JZRa6XXkTbQ/hqdefault.jpg #Beinkraft #SeniorenFitness #GesundAltern Vergiss Kniebeugen und entdecke die 1 einfache Übung, die deine Beinkraft auf natürliche Weise verbessern kann — ganz ohne Fitnessstudio, Pillen oder teure Geräte! Diese tägliche Bewegung wurde speziell für Senioren entwickelt, die stärkere Beine, besseres Gleichgewicht und mehr Mobilität zu Hause möchten. In diesem Video erfährst du, wie diese effektive Übung die Muskeln aktiviert, die Gelenkstabilität unterstützt und die Beweglichkeit im Alltag verbessert. Egal ob über 60, 70 oder 80 Jahre — diese seniorenfreundliche Routine hilft dir dabei, sicherer zu gehen, leichter aufzustehen und aktiv zu bleiben. Wenn du stärkere Beine, bessere Balance und mehr Sicherheit beim Gehen möchtest, könnte diese einfache Übung perfekt für deinen Alltag sein. Bleib aktiv, unabhängig und kümmere dich natürlich um deine Gesundheit. 👉 Abonniere den Kanal für weitere Gesundheitstipps für Senioren, Übungen zur Mobilität und natürliche Tipps für gesundes Altern! #Mobilität #StarkeBeine #SeniorenGesundheit #BalanceTraining #GesunderLebensstil https://www.youtube-nocookie.com/embed/JZRa6XXkTbQ 1467 2026-06-12T15:56:51.000Z 2026-10-22T19:54:14.128Z https://longevityharbor.com/de/watch/JZRa6XXkTbQ VERGISS KNIEBEUGEN! Diese 1 Übung verdoppelt sofort die Beinkraft! | Ohne Fitnessstudio! https://i.ytimg.com/vi/JZRa6XXkTbQ/hqdefault.jpg #Beinkraft #SeniorenFitness #GesundAltern Vergiss Kniebeugen und entdecke die 1 einfache Übung, die deine Beinkraft auf natürliche Weise verbessern kann — ganz ohne Fitnessstudio, Pillen oder teure Geräte! Diese tägliche Bewegung wurde speziell für Senioren entwickelt, die stärkere Beine, besseres Gleichgewicht und mehr Mobilität zu Hause möchten. In diesem Video erfährst du, wie diese effektive Übung die Muskeln aktiviert, die Gelenkstabilität unterstützt und die Beweglichkeit im Alltag verbessert. Egal ob über 60, 70 oder 80 Jahre — diese seniorenfreundliche Routine hilft dir dabei, sicherer zu gehen, leichter aufzustehen und aktiv zu bleiben. Wenn du stärkere Beine, bessere Balance und mehr Sicherheit beim Gehen möchtest, könnte diese einfache Übung perfekt für deinen Alltag sein. Bleib aktiv, unabhängig und kümmere dich natürlich um deine Gesundheit. 👉 Abonniere den Kanal für weitere Gesundheitstipps für Senioren, Übungen zur Mobilität und natürliche Tipps für gesundes Altern! #Mobilität #StarkeBeine #SeniorenGesundheit #BalanceTraining #GesunderLebensstil https://www.youtube-nocookie.com/embed/JZRa6XXkTbQ 1467 2026-06-12T15:56:51.000Z 2026-10-22T19:54:14.128Z https://longevityharbor.com/en/watch/JaVi_DxBlXw Senolytics video description: targeting aging cells and a question about forcing replication https://i.ytimg.com/vi/JaVi_DxBlXw/hqdefault.jpg The description says senolytics target aging cells, but that forcing remaining cells to replicate may accelerate their own aging, and asks whether a better approach to cellular health exists. https://www.youtube-nocookie.com/embed/JaVi_DxBlXw 131 2026-03-28T17:57:32.000Z 2026-10-23T01:51:29.460Z https://longevityharbor.com/de/watch/JaVi_DxBlXw Senolytika-Videobeschreibung: Ziel alternde Zellen und eine Frage zum erzwungenen Teilen https://i.ytimg.com/vi/JaVi_DxBlXw/hqdefault.jpg Die Beschreibung sagt, Senolytika zielen auf alternde Zellen, doch das Erzwingen der Teilung verbleibender Zellen könne deren eigene Alterung beschleunigen; sie fragt, ob es einen besseren Ansatz für zelluläre Gesundheit gibt. https://www.youtube-nocookie.com/embed/JaVi_DxBlXw 131 2026-03-28T17:57:32.000Z 2026-10-23T01:51:29.460Z https://longevityharbor.com/en/watch/Jn73AKqrnvw Creator calls NMN a favorite anti-aging supplement for energy and focus https://i.ytimg.com/vi/Jn73AKqrnvw/hqdefault.jpg In the description, the creator says NMN is one of their favorite anti-aging supplements to support overall energy and focus, and adds that results may vary. https://www.youtube-nocookie.com/embed/Jn73AKqrnvw 105 2026-06-26T17:28:39.000Z 2026-10-22T23:48:11.760Z https://longevityharbor.com/de/watch/Jn73AKqrnvw Ersteller nennt NMN sein liebstes Anti-Aging-Supplement für Energie und Fokus https://i.ytimg.com/vi/Jn73AKqrnvw/hqdefault.jpg In der Beschreibung sagt der Ersteller, NMN sei eines seiner liebsten Anti-Aging-Supplemente zur Unterstützung von allgemeiner Energie und Fokus, und ergänzt, dass Ergebnisse unterschiedlich ausfallen können. https://www.youtube-nocookie.com/embed/Jn73AKqrnvw 105 2026-06-26T17:28:39.000Z 2026-10-22T23:48:11.760Z https://longevityharbor.com/en/watch/JqaF58_vmvY Description: D+Q drug combo and senescent cell markers in humans https://i.ytimg.com/vi/JqaF58_vmvY/hqdefault.jpg According to the video description, senescent cells accumulate with age and drive inflammation, tissue damage and accelerated aging; a drug combination called D+Q has reportedly reduced senescent cell markers in human subjects. The description calls this educational only, not medical advice. https://www.youtube-nocookie.com/embed/JqaF58_vmvY 132 2026-04-17T22:30:10.000Z 2026-10-23T01:32:46.638Z https://longevityharbor.com/de/watch/JqaF58_vmvY Beschreibung: D+Q-Kombination und Marker seneszenter Zellen beim Menschen https://i.ytimg.com/vi/JqaF58_vmvY/hqdefault.jpg Laut Videobeschreibung reichern sich seneszente Zellen mit dem Alter an und treiben Entzündung, Gewebeschäden und beschleunigtes Altern voran; eine Wirkstoffkombination namens D+Q habe Marker seneszenter Zellen bei menschlichen Probanden reduziert. Die Beschreibung bezeichnet dies als rein edukativ, nicht als medizinischen Rat. https://www.youtube-nocookie.com/embed/JqaF58_vmvY 132 2026-04-17T22:30:10.000Z 2026-10-23T01:32:46.638Z https://longevityharbor.com/en/watch/Jqy_PQJOYNg The Best Diet for Healthy Aging (Updated) https://i.ytimg.com/vi/Jqy_PQJOYNg/hqdefault.jpg Food for healthy aging: Swapping just 1 percent of plant protein in place of animal protein was associated with significantly less age-related deficit accumulation. Aging is the topic of my forthcoming book, How Not to Age, out in 2023. I can’t wait to share all of what I found! This update has changes to the reference of eggs around 0:43. Some of my other popular videos on aging and longevity include: • How to Counter the Inflammation of Aging (https://nutritionfacts.org/video/how-to-counter-the-inflammation-of-aging/) • Fruits, Veggies, and Longevity: How Many Minutes Per Mouthful? (https://nutritionfacts.org/video/fruits-veggies-and-longevity-how-many-minutes-per-mouthful/) • Do Flexitarians Live Longer? (https://nutritionfacts.org/video/do-flexitarians-live-longer/) • Methionine Restriction as a Life-Extension Strategy (https://nutritionfacts.org/video/methionine-restriction-as-a-life-extension-strategy/) • How to Slow Brain Aging by Two Years (https://nutritionfacts.org/video/how-to-slow-brain-aging-by-two-years/) • Turning the Clock Back 14 Years (https://nutritionfacts.org/video/turning-the-clock-back-14-years/) • Longer Life Within Walking Distance (https://nutritionfacts.org/video/longer-life-within-walking-distance/) • Telomeres: Cap It All Off with Diet (https://nutritionfacts.org/video/telomeres-cap-it-all-off-with-diet/) • The Okinawa Diet: Living to 100 (https://nutritionfacts.org/video/the-okinawa-diet-living-to-100/) • Caloric Restriction vs. Animal-Protein Restriction (https://nutritionfacts.org/video/caloric-restriction-vs-animal-protein-restriction/) • Increased Lifespan from Beans (https://nutritionfacts.org/video/increased-lifespan-from-beans/) • The Benefits of Calorie Restriction for Longevity (https://nutritionfacts.org/video/the-benefits-of-calorie-restriction-for-longevity/) • Does Intermittent Fasting Increase Human Life Expectancy? (https://nutritionfacts.org/video/does-intermittent-fasting-increase-human-life-expectancy/) • How to Increase Your Life Expectancy 12 to 14 Years (https:/ https://www.youtube-nocookie.com/embed/Jqy_PQJOYNg 484 2023-11-21T19:16:28.000Z 2026-10-23T01:53:57.211Z https://longevityharbor.com/de/watch/Jqy_PQJOYNg The Best Diet for Healthy Aging (Updated) https://i.ytimg.com/vi/Jqy_PQJOYNg/hqdefault.jpg Food for healthy aging: Swapping just 1 percent of plant protein in place of animal protein was associated with significantly less age-related deficit accumulation. Aging is the topic of my forthcoming book, How Not to Age, out in 2023. I can’t wait to share all of what I found! This update has changes to the reference of eggs around 0:43. Some of my other popular videos on aging and longevity include: • How to Counter the Inflammation of Aging (https://nutritionfacts.org/video/how-to-counter-the-inflammation-of-aging/) • Fruits, Veggies, and Longevity: How Many Minutes Per Mouthful? (https://nutritionfacts.org/video/fruits-veggies-and-longevity-how-many-minutes-per-mouthful/) • Do Flexitarians Live Longer? (https://nutritionfacts.org/video/do-flexitarians-live-longer/) • Methionine Restriction as a Life-Extension Strategy (https://nutritionfacts.org/video/methionine-restriction-as-a-life-extension-strategy/) • How to Slow Brain Aging by Two Years (https://nutritionfacts.org/video/how-to-slow-brain-aging-by-two-years/) • Turning the Clock Back 14 Years (https://nutritionfacts.org/video/turning-the-clock-back-14-years/) • Longer Life Within Walking Distance (https://nutritionfacts.org/video/longer-life-within-walking-distance/) • Telomeres: Cap It All Off with Diet (https://nutritionfacts.org/video/telomeres-cap-it-all-off-with-diet/) • The Okinawa Diet: Living to 100 (https://nutritionfacts.org/video/the-okinawa-diet-living-to-100/) • Caloric Restriction vs. Animal-Protein Restriction (https://nutritionfacts.org/video/caloric-restriction-vs-animal-protein-restriction/) • Increased Lifespan from Beans (https://nutritionfacts.org/video/increased-lifespan-from-beans/) • The Benefits of Calorie Restriction for Longevity (https://nutritionfacts.org/video/the-benefits-of-calorie-restriction-for-longevity/) • Does Intermittent Fasting Increase Human Life Expectancy? (https://nutritionfacts.org/video/does-intermittent-fasting-increase-human-life-expectancy/) • How to Increase Your Life Expectancy 12 to 14 Years (https:/ https://www.youtube-nocookie.com/embed/Jqy_PQJOYNg 484 2023-11-21T19:16:28.000Z 2026-10-23T01:53:57.211Z https://longevityharbor.com/en/watch/Jt9jQAcp0k8 Creator reports no measurable change from NMN and NR in a 1-year self-test https://i.ytimg.com/vi/Jt9jQAcp0k8/hqdefault.jpg In the description, Zac Armstrong says a 1-year experiment with $79 NMN and NR supplements showed zero measurable improvements in tracked markers such as HRV, resting heart rate, deep sleep, inflammation and metabolic blood panels. This is a creator account, not a controlled study. https://www.youtube-nocookie.com/embed/Jt9jQAcp0k8 91 2026-09-19T17:00:21.000Z 2026-10-22T22:04:35.060Z https://longevityharbor.com/de/watch/Jt9jQAcp0k8 Creator berichtet von keinen messbaren Veränderungen durch NMN und NR in einem 1-Jahres-Selbsttest https://i.ytimg.com/vi/Jt9jQAcp0k8/hqdefault.jpg In der Beschreibung sagt Zac Armstrong, ein 1-Jahres-Experiment mit 79-Dollar-NMN- und -NR-Präparaten habe null messbare Verbesserungen bei verfolgten Markern wie HRV, Ruhepuls, Tiefschlaf, Entzündung und metabolischen Blutpanels gezeigt. Das ist ein Creator-Bericht, keine kontrollierte Studie. https://www.youtube-nocookie.com/embed/Jt9jQAcp0k8 91 2026-09-19T17:00:21.000Z 2026-10-22T22:04:35.060Z https://longevityharbor.com/en/watch/JwD2bH_nMS0 Video description: stretching and biological aging, from fascia to telomeres https://i.ytimg.com/vi/JwD2bH_nMS0/hqdefault.jpg The description says the video explores how stretching may affect fascia, cells, DNA, telomeres, inflammation, nitric oxide and blood flow, and links mechanical forces to cellular repair and longevity. It cites ten references but reports no study results of its own. https://www.youtube-nocookie.com/embed/JwD2bH_nMS0 1790 2026-06-21T17:00:15.000Z 2026-10-22T23:53:23.473Z https://longevityharbor.com/de/watch/JwD2bH_nMS0 Videobeschreibung: Stretching und biologisches Altern, von der Faszie bis zu Telomeren https://i.ytimg.com/vi/JwD2bH_nMS0/hqdefault.jpg Laut Beschreibung untersucht das Video, wie Stretching Faszie, Zellen, DNA, Telomere, Entzündung, Stickstoffmonoxid und Durchblutung beeinflussen könnte, und verknüpft mechanische Kräfte mit Zellreparatur und Langlebigkeit. Es nennt zehn Quellen, berichtet aber keine eigenen Studienergebnisse. https://www.youtube-nocookie.com/embed/JwD2bH_nMS0 1790 2026-06-21T17:00:15.000Z 2026-10-22T23:53:23.473Z https://longevityharbor.com/en/watch/JwnZ8Z2KSWw Video description links thigh size to heart disease and early death https://i.ytimg.com/vi/JwnZ8Z2KSWw/hqdefault.jpg The description cites a British Medical Journal study of nearly 3,000 adults in which thigh size independently predicted heart disease and early death, and says a follow-up analysis of 2.5 million people confirmed it. https://www.youtube-nocookie.com/embed/JwnZ8Z2KSWw 138 2026-06-12T21:30:16.000Z 2026-10-22T23:59:39.393Z https://longevityharbor.com/de/watch/JwnZ8Z2KSWw Videobeschreibung verknüpft Oberschenkelumfang mit Herzkrankheit und frühem Tod https://i.ytimg.com/vi/JwnZ8Z2KSWw/hqdefault.jpg Die Beschreibung nennt eine Studie im British Medical Journal mit fast 3.000 Erwachsenen, in der der Oberschenkelumfang Herzkrankheit und frühen Tod unabhängig vorhersagte, und sagt, eine Folgeanalyse von 2,5 Millionen Menschen habe dies bestätigt. https://www.youtube-nocookie.com/embed/JwnZ8Z2KSWw 138 2026-06-12T21:30:16.000Z 2026-10-22T23:59:39.393Z https://longevityharbor.com/en/watch/Jz833ii2Glk Ronald Kohanski | Geroscience https://i.ytimg.com/vi/Jz833ii2Glk/hqdefault.jpg On the second day of Ending Age-Related Diseases 2019, Ronald Kohanski of the NIA gave a keynote speech entitled Concepts and Perspectives in Geroscience. He discussed the ways in which aging affects systems and cells, the problems with using lifespan as an endpoint, the concept of resiliency, parabiosis, telomeres, unexpected effects at a distance with regards to interventions, and several in-depth concepts relating to the aging of specific cell types, such as muscle and brain cells. ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a Lifespan Hero: http://lifespan.io/hero #Aging #Rejuvenation #NIA https://www.youtube-nocookie.com/embed/Jz833ii2Glk 1880 2019-08-16T15:10:31.000Z 2026-10-22T17:43:40.106Z https://longevityharbor.com/de/watch/Jz833ii2Glk Ronald Kohanski | Geroscience https://i.ytimg.com/vi/Jz833ii2Glk/hqdefault.jpg On the second day of Ending Age-Related Diseases 2019, Ronald Kohanski of the NIA gave a keynote speech entitled Concepts and Perspectives in Geroscience. He discussed the ways in which aging affects systems and cells, the problems with using lifespan as an endpoint, the concept of resiliency, parabiosis, telomeres, unexpected effects at a distance with regards to interventions, and several in-depth concepts relating to the aging of specific cell types, such as muscle and brain cells. ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a Lifespan Hero: http://lifespan.io/hero #Aging #Rejuvenation #NIA https://www.youtube-nocookie.com/embed/Jz833ii2Glk 1880 2019-08-16T15:10:31.000Z 2026-10-22T17:43:40.106Z https://longevityharbor.com/en/watch/K78iKQJnTdE Video description on epigenetic clocks and claimed biological age https://i.ytimg.com/vi/K78iKQJnTdE/hqdefault.jpg The description says epigenetic clocks can reveal a person's "TRUE biological age" through DNA methylation patterns and promises help to measure and support it. It names Horvath, GrimAge and DunedinPACE in the title but gives no data, study details or results. https://www.youtube-nocookie.com/embed/K78iKQJnTdE 209 2026-07-24T14:07:47.000Z 2026-10-22T23:22:55.257Z https://longevityharbor.com/de/watch/K78iKQJnTdE Videobeschreibung zu epigenetischen Uhren und behauptetem biologischem Alter https://i.ytimg.com/vi/K78iKQJnTdE/hqdefault.jpg Die Beschreibung sagt, epigenetische Uhren könnten über DNA-Methylierungsmuster das „wahre biologische Alter“ zeigen, und verspricht Hilfe beim Messen und Unterstützen. Im Titel werden Horvath, GrimAge und DunedinPACE genannt, doch Daten, Studiendetails oder Ergebnisse fehlen. https://www.youtube-nocookie.com/embed/K78iKQJnTdE 209 2026-07-24T14:07:47.000Z 2026-10-22T23:22:55.257Z https://longevityharbor.com/en/watch/KD-FmeueFUo Healthy Aging with Nutrition https://i.ytimg.com/vi/KD-FmeueFUo/hqdefault.jpg A well-balanced diet full of essential nutrients can help support a healthy life. However, people with deficiencies, certain diseases and conditions, or with evolving nutritional needs at different stages of life may consider dietary supplements to add missing nutrients to their diets. Supplements are not regulated as strictly as drugs by the FDA, and headlines on nutritional recommendations seem to change from day to day. Watch this film for tips on a healthy diet, how to safely turn to supplements, and how to be a well-educated consumer. Learn more by going to agingresearch.org/NutritionFilms https://www.youtube-nocookie.com/embed/KD-FmeueFUo 344 2016-03-07T17:39:41.000Z 2026-10-23T01:53:57.107Z https://longevityharbor.com/de/watch/KD-FmeueFUo Healthy Aging with Nutrition https://i.ytimg.com/vi/KD-FmeueFUo/hqdefault.jpg A well-balanced diet full of essential nutrients can help support a healthy life. However, people with deficiencies, certain diseases and conditions, or with evolving nutritional needs at different stages of life may consider dietary supplements to add missing nutrients to their diets. Supplements are not regulated as strictly as drugs by the FDA, and headlines on nutritional recommendations seem to change from day to day. Watch this film for tips on a healthy diet, how to safely turn to supplements, and how to be a well-educated consumer. Learn more by going to agingresearch.org/NutritionFilms https://www.youtube-nocookie.com/embed/KD-FmeueFUo 344 2016-03-07T17:39:41.000Z 2026-10-23T01:53:57.107Z https://longevityharbor.com/en/watch/KHnfgAiq_sk Cellular Senescence and Mitochondria | Prof Joao Passos https://i.ytimg.com/vi/KHnfgAiq_sk/hqdefault.jpg In this #webinar, Prof Joao Passos, Professor and Director of the Cell and Molecular Ageing Laboratory at Mayo Clinic discussed the link between mitochondria and cellular senescence. Prof Passos's laboratory has made several important contributions to the understanding of the mechanisms driving cellular senescence in ageing and age-related diseases, with a particular emphasis on telomeres and mitochondria. Register for upcoming #HealthyLongevity #webinar sessions at https://bit.ly/3F0IlRd #NUSMedicine #webinarseries Closing video source: https://www.youtube.com/watch?v=F8IxttK_0Wo Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material. https://www.youtube-nocookie.com/embed/KHnfgAiq_sk 4007 2023-10-13T01:25:24.000Z 2026-10-23T02:56:02.626Z https://longevityharbor.com/de/watch/KHnfgAiq_sk Cellular Senescence and Mitochondria | Prof Joao Passos https://i.ytimg.com/vi/KHnfgAiq_sk/hqdefault.jpg In this #webinar, Prof Joao Passos, Professor and Director of the Cell and Molecular Ageing Laboratory at Mayo Clinic discussed the link between mitochondria and cellular senescence. Prof Passos's laboratory has made several important contributions to the understanding of the mechanisms driving cellular senescence in ageing and age-related diseases, with a particular emphasis on telomeres and mitochondria. Register for upcoming #HealthyLongevity #webinar sessions at https://bit.ly/3F0IlRd #NUSMedicine #webinarseries Closing video source: https://www.youtube.com/watch?v=F8IxttK_0Wo Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material. https://www.youtube-nocookie.com/embed/KHnfgAiq_sk 4007 2023-10-13T01:25:24.000Z 2026-10-23T02:56:02.626Z https://longevityharbor.com/en/watch/KKGqQOyGK1Y Video description compares senolytics with partial reprogramming research https://i.ytimg.com/vi/KKGqQOyGK1Y/hqdefault.jpg The description says the episode contrasts removing senescent cells with partially reprogramming living cells, moving from Yamanaka factors and mouse studies to an early human trial for optic nerve diseases. https://www.youtube-nocookie.com/embed/KKGqQOyGK1Y 441 2026-09-22T05:29:29.000Z 2026-10-22T21:58:20.945Z https://longevityharbor.com/de/watch/KKGqQOyGK1Y Videobeschreibung vergleicht Senolytika mit Teil-Reprogrammierung https://i.ytimg.com/vi/KKGqQOyGK1Y/hqdefault.jpg Laut Beschreibung vergleicht die Folge das Entfernen seneszenter Zellen mit der Teil-Reprogrammierung lebender Zellen – von Yamanaka-Faktoren und Mausstudien bis zu einer frühen Humanstudie bei Sehnervenerkrankungen. https://www.youtube-nocookie.com/embed/KKGqQOyGK1Y 441 2026-09-22T05:29:29.000Z 2026-10-22T21:58:20.945Z https://longevityharbor.com/en/watch/KM83vVpXihU Epigenetic Clocks: Can We Measure Biological Age? https://i.ytimg.com/vi/KM83vVpXihU/hqdefault.jpg Can we truly measure how fast we’re aging? In this video, we explore the fascinating science of epigenetic clocks—tools that analyze DNA methylation patterns to estimate biological age. Learn how these clocks work, what they reveal about your health and longevity, and whether they can help slow the aging process. https://www.youtube-nocookie.com/embed/KM83vVpXihU 469 2025-07-05T04:00:06.000Z 2026-10-22T18:32:06.788Z https://longevityharbor.com/de/watch/KM83vVpXihU Epigenetic Clocks: Can We Measure Biological Age? https://i.ytimg.com/vi/KM83vVpXihU/hqdefault.jpg Can we truly measure how fast we’re aging? In this video, we explore the fascinating science of epigenetic clocks—tools that analyze DNA methylation patterns to estimate biological age. Learn how these clocks work, what they reveal about your health and longevity, and whether they can help slow the aging process. https://www.youtube-nocookie.com/embed/KM83vVpXihU 469 2025-07-05T04:00:06.000Z 2026-10-22T18:32:06.788Z https://longevityharbor.com/en/watch/KTbKIz2AEdY The Number 1 Anti-Aging Supplement of 2026. #antiaging #2026trends #nmn #robertlove https://i.ytimg.com/vi/KTbKIz2AEdY/hqdefault.jpg The Number 1 Anti-Aging Supplement of 2026. #antiaging #2026trends #nmn #robertlove https://www.youtube-nocookie.com/embed/KTbKIz2AEdY 150 2026-01-02T15:00:41.000Z 2026-10-22T17:43:42.563Z https://longevityharbor.com/de/watch/KTbKIz2AEdY The Number 1 Anti-Aging Supplement of 2026. #antiaging #2026trends #nmn #robertlove https://i.ytimg.com/vi/KTbKIz2AEdY/hqdefault.jpg The Number 1 Anti-Aging Supplement of 2026. #antiaging #2026trends #nmn #robertlove https://www.youtube-nocookie.com/embed/KTbKIz2AEdY 150 2026-01-02T15:00:41.000Z 2026-10-22T17:43:42.563Z https://longevityharbor.com/en/watch/KVF_N2a3IjM Epigenetik – Prof. Dr. Björn Schumacher über epigenetische Uhren und die epigenetische Alterung https://i.ytimg.com/vi/KVF_N2a3IjM/hqdefault.jpg In diesem Podcast spreche ich mit Prof. Dr. Björn Schumacher über den Forschungsstand von epigenetischen Uhren. Prof. Dr. Schumacher ist Direktor des Instituts für Genomstabilität bei Alterung und Erkrankung am CECAD-Forschungszentrum der Uni Köln. Er sagt: „Nur wenn wir den Alterungsprozess verstehen, wird es uns gelingen Alterskrankheiten wirksam zu verhindern und ein gesundes Altern zu ermöglichen.“ In dieser Folge behandeln wir folgende Fragen: - Was die Epigenetik und die Genetik unterscheidet. - Wie epigenetische Uhren das biologische Alter auslesen. - Wo momentan noch die Grenzen der epigenetischen Uhren sind. - Wie man einen guten epigenetischen Test erkennt. - Wie bestimmte Lebensstilfaktoren über die Epigenetik an die nächste Generation weitergegeben werden kann. Weitere Informationen zu Prof. Dr. Björn Schumacher findest du hier: https://www.cecad.uni-koeln.de/research/principal-investigators/full-members/bjoern-schumacher Nächste Woche folgt eine weitere Folge mit Prof. Dr. Schumacher in der wir diskutieren, wie wir diese epigenetischen Faktoren reprogrammieren können. Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder Youtube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an deinen Arzt/deine Ärztin. STY-114 https://www.youtube-nocookie.com/embed/KVF_N2a3IjM 2513 2024-08-16T04:00:07.000Z 2026-10-22T17:11:30.657Z https://longevityharbor.com/de/watch/KVF_N2a3IjM Epigenetik – Prof. Dr. Björn Schumacher über epigenetische Uhren und die epigenetische Alterung https://i.ytimg.com/vi/KVF_N2a3IjM/hqdefault.jpg In diesem Podcast spreche ich mit Prof. Dr. Björn Schumacher über den Forschungsstand von epigenetischen Uhren. Prof. Dr. Schumacher ist Direktor des Instituts für Genomstabilität bei Alterung und Erkrankung am CECAD-Forschungszentrum der Uni Köln. Er sagt: „Nur wenn wir den Alterungsprozess verstehen, wird es uns gelingen Alterskrankheiten wirksam zu verhindern und ein gesundes Altern zu ermöglichen.“ In dieser Folge behandeln wir folgende Fragen: - Was die Epigenetik und die Genetik unterscheidet. - Wie epigenetische Uhren das biologische Alter auslesen. - Wo momentan noch die Grenzen der epigenetischen Uhren sind. - Wie man einen guten epigenetischen Test erkennt. - Wie bestimmte Lebensstilfaktoren über die Epigenetik an die nächste Generation weitergegeben werden kann. Weitere Informationen zu Prof. Dr. Björn Schumacher findest du hier: https://www.cecad.uni-koeln.de/research/principal-investigators/full-members/bjoern-schumacher Nächste Woche folgt eine weitere Folge mit Prof. Dr. Schumacher in der wir diskutieren, wie wir diese epigenetischen Faktoren reprogrammieren können. Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder Youtube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an deinen Arzt/deine Ärztin. STY-114 https://www.youtube-nocookie.com/embed/KVF_N2a3IjM 2513 2024-08-16T04:00:07.000Z 2026-10-22T17:11:30.657Z https://longevityharbor.com/en/watch/KWxGSvktPp0 What Does Aging Better Mean to Kelly Slater https://i.ytimg.com/vi/KWxGSvktPp0/hqdefault.jpg What does it mean to age better? Professional surfer Kelly Slater shares his perspective on longevity, recovery, and taking care of yourself for the years ahead. After years in the ocean, the 11-time World Surf League Champion knows that every wave brings something new. Now in his 50s, Kelly approaches health and aging differently, with a greater focus on recovery, long-term well-being, and staying ready for what comes next. Kelly also shares why science matters when it comes to health and discusses his experience with Tru Niagen, powered by nicotinamide riboside (NR), a precursor to NAD+ that supports cellular health. Backed by more than 45 published clinical studies and over 25 years of research, Tru Niagen is committed to advancing our understanding of NAD+ and healthy aging. Aging is a part of life, but how we approach it matters. Think about the future while taking care of yourself in the present. Don't get old. Age better. Discover the science behind Tru Niagen: www.agebetter.com These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. #KellySlater #TruNiagen #HealthyAging #Longevity #NAD #CellularHealth https://www.youtube-nocookie.com/embed/KWxGSvktPp0 124 2026-10-13T17:07:03.000Z 2026-10-22T19:04:44.970Z https://longevityharbor.com/de/watch/KWxGSvktPp0 What Does Aging Better Mean to Kelly Slater https://i.ytimg.com/vi/KWxGSvktPp0/hqdefault.jpg What does it mean to age better? Professional surfer Kelly Slater shares his perspective on longevity, recovery, and taking care of yourself for the years ahead. After years in the ocean, the 11-time World Surf League Champion knows that every wave brings something new. Now in his 50s, Kelly approaches health and aging differently, with a greater focus on recovery, long-term well-being, and staying ready for what comes next. Kelly also shares why science matters when it comes to health and discusses his experience with Tru Niagen, powered by nicotinamide riboside (NR), a precursor to NAD+ that supports cellular health. Backed by more than 45 published clinical studies and over 25 years of research, Tru Niagen is committed to advancing our understanding of NAD+ and healthy aging. Aging is a part of life, but how we approach it matters. Think about the future while taking care of yourself in the present. Don't get old. Age better. Discover the science behind Tru Niagen: www.agebetter.com These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. #KellySlater #TruNiagen #HealthyAging #Longevity #NAD #CellularHealth https://www.youtube-nocookie.com/embed/KWxGSvktPp0 124 2026-10-13T17:07:03.000Z 2026-10-22T19:04:44.970Z https://longevityharbor.com/en/watch/KX5-y6wxwTA Nach 65 noch 30 Jahre leben? 6 Dinge morgens für gesundes Altern https://i.ytimg.com/vi/KX5-y6wxwTA/hqdefault.jpg Nach 65 noch 30 Jahre leben? 6 Dinge morgens für gesundes Altern – laut Harvard-Studie. Forscher der Harvard University haben über 20 Jahre 44.000 Erwachsene über 60 begleitet: 6 einfache Morgen-Gewohnheiten können den Unterschied für gesund altern, Gedächtnis, Beinkraft und langlebigkeit machen. Ideal für alle mit Fokus auf gesundheit ab 60 und senioren gesundheit. In diesem Video erfahren Sie: - 470 ml Wasser direkt nach dem Aufwachen: laut NIH mit 41% niedrigerem Herzinfarkt- und 37% niedrigerem Schlaganfall-Risiko verbunden - 10 Minuten Morgenlicht: laut Johns Hopkins mit Telomer-Schutz und bis zu 5 Jahren jüngerem biologischen Alter verbunden - 30 g Protein innerhalb von 90 Minuten nach dem Aufwachen: laut UTMB mit 73% mehr Muskelerhalt gegen altersbedingten Abbau - 60 Sekunden Gleichgewichtstraining täglich: laut Mayo Clinic mit 86% niedrigerem Sturzrisiko verbunden; wer 10 Sekunden Einbein-Stand nicht schafft, hatte 84% höheres Sterberisiko - 4-7-8-Atmung: laut UCLA-Forschung mit 43% mehr Telomerase-Aktivität, ca. 10 Punkten niedrigerem Blutdruck und bis zu 50% niedrigerem Cortisol verbunden - sanfte Aktivierung durch Bewegung am Morgen für Kreislauf, Gelenke und Energie Starten Sie mit 1 Gewohnheit und fügen Sie jede Woche eine weitere hinzu – besonders ab 60. 🔔 Abonnieren Sie Tief Erklärt für wöchentliche Videos zu Psychologie, gesundheit ab 60 und Neurowissenschaft – verständlich und wissenschaftlich fundiert. ⚠️ Hinweis: Nur zu Bildungs- und Informationszwecken, kein Ersatz für ärztliche Beratung. Sprechen Sie bei Vorerkrankungen mit Ihrer Ärztin oder Ihrem Arzt. #GesundAb60 #GesundAltern #Morgenroutine #Langlebigkeit #SeniorenGesundheit https://www.youtube-nocookie.com/embed/KX5-y6wxwTA 1476 2026-10-17T08:00:29.000Z 2026-10-22T19:43:44.421Z https://longevityharbor.com/de/watch/KX5-y6wxwTA Nach 65 noch 30 Jahre leben? 6 Dinge morgens für gesundes Altern https://i.ytimg.com/vi/KX5-y6wxwTA/hqdefault.jpg Nach 65 noch 30 Jahre leben? 6 Dinge morgens für gesundes Altern – laut Harvard-Studie. Forscher der Harvard University haben über 20 Jahre 44.000 Erwachsene über 60 begleitet: 6 einfache Morgen-Gewohnheiten können den Unterschied für gesund altern, Gedächtnis, Beinkraft und langlebigkeit machen. Ideal für alle mit Fokus auf gesundheit ab 60 und senioren gesundheit. In diesem Video erfahren Sie: - 470 ml Wasser direkt nach dem Aufwachen: laut NIH mit 41% niedrigerem Herzinfarkt- und 37% niedrigerem Schlaganfall-Risiko verbunden - 10 Minuten Morgenlicht: laut Johns Hopkins mit Telomer-Schutz und bis zu 5 Jahren jüngerem biologischen Alter verbunden - 30 g Protein innerhalb von 90 Minuten nach dem Aufwachen: laut UTMB mit 73% mehr Muskelerhalt gegen altersbedingten Abbau - 60 Sekunden Gleichgewichtstraining täglich: laut Mayo Clinic mit 86% niedrigerem Sturzrisiko verbunden; wer 10 Sekunden Einbein-Stand nicht schafft, hatte 84% höheres Sterberisiko - 4-7-8-Atmung: laut UCLA-Forschung mit 43% mehr Telomerase-Aktivität, ca. 10 Punkten niedrigerem Blutdruck und bis zu 50% niedrigerem Cortisol verbunden - sanfte Aktivierung durch Bewegung am Morgen für Kreislauf, Gelenke und Energie Starten Sie mit 1 Gewohnheit und fügen Sie jede Woche eine weitere hinzu – besonders ab 60. 🔔 Abonnieren Sie Tief Erklärt für wöchentliche Videos zu Psychologie, gesundheit ab 60 und Neurowissenschaft – verständlich und wissenschaftlich fundiert. ⚠️ Hinweis: Nur zu Bildungs- und Informationszwecken, kein Ersatz für ärztliche Beratung. Sprechen Sie bei Vorerkrankungen mit Ihrer Ärztin oder Ihrem Arzt. #GesundAb60 #GesundAltern #Morgenroutine #Langlebigkeit #SeniorenGesundheit https://www.youtube-nocookie.com/embed/KX5-y6wxwTA 1476 2026-10-17T08:00:29.000Z 2026-10-22T19:43:44.421Z https://longevityharbor.com/en/watch/KZzzBLgiWcg Link Between mTOR & Aging | Importance Of mTOR Pathways For Aging | Longevity https://i.ytimg.com/vi/KZzzBLgiWcg/hqdefault.jpg The mTOR (mechanistic Target of Rapamycin) pathway is a crucial regulator of various cellular processes, playing a significant role in growth, metabolism, and the complex process of aging. This pathway profoundly influences how our cells respond to nutrients, growth factors, and cellular stress, ultimately impacting both longevity and healthspan. This video is taken from a podcast featuring our honored guest, Dr. Morgan Camp, who delves into the profound importance of mTOR pathways for aging and overall health. Dr. Camp provides expert insights into how these pathways function and their significant implications for health as we age. Throughout our discussion, we focus on the role of mTOR in age-associated conditions, emphasizing its relevance in the evolving field of longevity research and health optimization. 👇👇👇 Link To Full Podcast: https://www.youtube.com/watch?v=usoB4rCScew In this video, we thoroughly explore what mTOR is and why it is vital for understanding the aging process at both cellular and systemic levels. We delve into the importance of mTOR pathways and how they impact various age-associated conditions, from metabolic disorders to neurodegenerative diseases. Additionally, we examine the relationship between mTOR and lifespan extension, shedding light on the intricate connections between cellular health, nutrient sensing, and the aging process. The consequences of mTOR activation and inhibition significantly influence the aging process and overall cellular health. This exploration highlights potential therapeutic targets for mTOR modulation and underscores the importance of maintaining balance within these pathways. By understanding mTOR dynamics, researchers can develop innovative strategies to mitigate age-related diseases and promote healthier aging. These insights into mTOR's role in longevity could lead to treatments that enhance healthspan and improve quality of life for aging populations, making this knowledge essential for both researchers and healthcare practitioners. 00:00 Intro https://www.youtube-nocookie.com/embed/KZzzBLgiWcg 341 2024-10-22T13:00:20.000Z 2026-10-22T19:32:36.423Z https://longevityharbor.com/de/watch/KZzzBLgiWcg Link Between mTOR & Aging | Importance Of mTOR Pathways For Aging | Longevity https://i.ytimg.com/vi/KZzzBLgiWcg/hqdefault.jpg The mTOR (mechanistic Target of Rapamycin) pathway is a crucial regulator of various cellular processes, playing a significant role in growth, metabolism, and the complex process of aging. This pathway profoundly influences how our cells respond to nutrients, growth factors, and cellular stress, ultimately impacting both longevity and healthspan. This video is taken from a podcast featuring our honored guest, Dr. Morgan Camp, who delves into the profound importance of mTOR pathways for aging and overall health. Dr. Camp provides expert insights into how these pathways function and their significant implications for health as we age. Throughout our discussion, we focus on the role of mTOR in age-associated conditions, emphasizing its relevance in the evolving field of longevity research and health optimization. 👇👇👇 Link To Full Podcast: https://www.youtube.com/watch?v=usoB4rCScew In this video, we thoroughly explore what mTOR is and why it is vital for understanding the aging process at both cellular and systemic levels. We delve into the importance of mTOR pathways and how they impact various age-associated conditions, from metabolic disorders to neurodegenerative diseases. Additionally, we examine the relationship between mTOR and lifespan extension, shedding light on the intricate connections between cellular health, nutrient sensing, and the aging process. The consequences of mTOR activation and inhibition significantly influence the aging process and overall cellular health. This exploration highlights potential therapeutic targets for mTOR modulation and underscores the importance of maintaining balance within these pathways. By understanding mTOR dynamics, researchers can develop innovative strategies to mitigate age-related diseases and promote healthier aging. These insights into mTOR's role in longevity could lead to treatments that enhance healthspan and improve quality of life for aging populations, making this knowledge essential for both researchers and healthcare practitioners. 00:00 Intro https://www.youtube-nocookie.com/embed/KZzzBLgiWcg 341 2024-10-22T13:00:20.000Z 2026-10-22T19:32:36.423Z https://longevityharbor.com/en/watch/KbgoV9dTPf8 Aging Reversed! Part 5 - Calorie Restriction and Fasting https://i.ytimg.com/vi/KbgoV9dTPf8/hqdefault.jpg In this series, we're talking about how to stop or even reverse aging based on some scientific research in this specific field. Thus far, we've explored the idea of treating aging as a disease. We have also gone into the information theory of aging and studied several genes that are particularly important in the aging process and, more importantly, in the potential for reversing aging. Today is all about caloric restriction and fasting: we'll discuss the benefits of calorie restriction and intermittent fasting on longevity. Read the full post at http://RunningAFEVER.com/392 Dig the episode? Check out the full playlist to watch the whole Aging Reversed! series: https://www.youtube.com/playlist?list=PL0-YNhuffh8_qo5IWl5U-xSmswyPzSU5C https://www.youtube-nocookie.com/embed/KbgoV9dTPf8 590 2025-02-26T18:00:28.000Z 2026-10-22T19:54:18.402Z https://longevityharbor.com/de/watch/KbgoV9dTPf8 Aging Reversed! Part 5 - Calorie Restriction and Fasting https://i.ytimg.com/vi/KbgoV9dTPf8/hqdefault.jpg In this series, we're talking about how to stop or even reverse aging based on some scientific research in this specific field. Thus far, we've explored the idea of treating aging as a disease. We have also gone into the information theory of aging and studied several genes that are particularly important in the aging process and, more importantly, in the potential for reversing aging. Today is all about caloric restriction and fasting: we'll discuss the benefits of calorie restriction and intermittent fasting on longevity. Read the full post at http://RunningAFEVER.com/392 Dig the episode? Check out the full playlist to watch the whole Aging Reversed! series: https://www.youtube.com/playlist?list=PL0-YNhuffh8_qo5IWl5U-xSmswyPzSU5C https://www.youtube-nocookie.com/embed/KbgoV9dTPf8 590 2025-02-26T18:00:28.000Z 2026-10-22T19:54:18.402Z https://longevityharbor.com/en/watch/KewQ7qZAYV0 Longevity on Your Plate: The Role of Diet in Aging and Healthspan with Dr. Cristal M. Hill, USC https://i.ytimg.com/vi/KewQ7qZAYV0/hqdefault.jpg Emerging research emphasizes the impact of caloric intake, macronutrient composition, and dietary patterns on aging and longevity. Caloric restriction and intermittent fasting have been associated with extended lifespan and delayed onset of age-related diseases by promoting cellular repair mechanisms and metabolic efficiency. Additionally, diets rich in plant-based foods, healthy fats, and lean proteins—such as the Mediterranean and Blue Zone diets—have been linked to improved longevity and reduced risk of chronic conditions like cardiovascular disease, diabetes, and neurodegenerative disorders. Conversely, diets high in processed foods, refined sugars, and unhealthy fats contribute to inflammation, oxidative stress, and shortened lifespan. This talk with review established mechanisms through which diet influences aging, including molecular pathways and metabolic regulation to extend lifespan. Understanding the relationship between nutrition and longevity can inform dietary recommendations and interventions aimed at promoting healthier aging and extended lifespan. **This presentation is made possible by the LSAC DEIR Grant** https://www.youtube-nocookie.com/embed/KewQ7qZAYV0 4118 2025-03-18T03:25:06.000Z 2026-10-22T18:32:09.957Z https://longevityharbor.com/de/watch/KewQ7qZAYV0 Longevity on Your Plate: The Role of Diet in Aging and Healthspan with Dr. Cristal M. Hill, USC https://i.ytimg.com/vi/KewQ7qZAYV0/hqdefault.jpg Emerging research emphasizes the impact of caloric intake, macronutrient composition, and dietary patterns on aging and longevity. Caloric restriction and intermittent fasting have been associated with extended lifespan and delayed onset of age-related diseases by promoting cellular repair mechanisms and metabolic efficiency. Additionally, diets rich in plant-based foods, healthy fats, and lean proteins—such as the Mediterranean and Blue Zone diets—have been linked to improved longevity and reduced risk of chronic conditions like cardiovascular disease, diabetes, and neurodegenerative disorders. Conversely, diets high in processed foods, refined sugars, and unhealthy fats contribute to inflammation, oxidative stress, and shortened lifespan. This talk with review established mechanisms through which diet influences aging, including molecular pathways and metabolic regulation to extend lifespan. Understanding the relationship between nutrition and longevity can inform dietary recommendations and interventions aimed at promoting healthier aging and extended lifespan. **This presentation is made possible by the LSAC DEIR Grant** https://www.youtube-nocookie.com/embed/KewQ7qZAYV0 4118 2025-03-18T03:25:06.000Z 2026-10-22T18:32:09.957Z https://longevityharbor.com/en/watch/KmALrmPIgEc Steve Horvath on epigenetic clocks, age-reversal claims and organ-by-organ rejuvenation https://i.ytimg.com/vi/KmALrmPIgEc/hqdefault.jpg In this podcast description, Steve Horvath discusses why epigenetic clocks differ, why dramatic age-reversal claims need scrutiny, and why routine clinical use is not yet here; the description notes that a cited vision study was in mice. https://www.youtube-nocookie.com/embed/KmALrmPIgEc 1297 2026-10-12T16:00:12.000Z 2026-10-22T20:24:34.223Z https://longevityharbor.com/de/watch/KmALrmPIgEc Steve Horvath über epigenetische Uhren, Altersumkehr-Behauptungen und Verjüngung Organ für Organ https://i.ytimg.com/vi/KmALrmPIgEc/hqdefault.jpg In dieser Podcast-Beschreibung spricht Steve Horvath darüber, warum epigenetische Uhren unterschiedlich ausfallen, warum dramatische Altersumkehr-Behauptungen geprüft werden müssen und warum der Routineeinsatz in der Klinik noch nicht da ist; die Beschreibung nennt eine zitierte Sehstudie an Mäusen. https://www.youtube-nocookie.com/embed/KmALrmPIgEc 1297 2026-10-12T16:00:12.000Z 2026-10-22T20:24:34.223Z https://longevityharbor.com/en/watch/Ksf12i9L5FU Video description: calorie restriction and cellular repair https://i.ytimg.com/vi/Ksf12i9L5FU/hqdefault.jpg The description says calorie restriction technically improves cellular repair, but probably without a noticeable difference. It points to macrosinc.net for more. https://www.youtube-nocookie.com/embed/Ksf12i9L5FU 133 2026-02-01T17:55:40.000Z 2026-10-23T02:41:33.687Z https://longevityharbor.com/de/watch/Ksf12i9L5FU Videobeschreibung: Kalorienrestriktion und Zellreparatur https://i.ytimg.com/vi/Ksf12i9L5FU/hqdefault.jpg Die Beschreibung sagt, Kalorienrestriktion verbessere die Zellreparatur technisch gesehen, wahrscheinlich aber ohne spürbaren Unterschied. Für mehr verweist sie auf macrosinc.net. https://www.youtube-nocookie.com/embed/Ksf12i9L5FU 133 2026-02-01T17:55:40.000Z 2026-10-23T02:41:33.687Z https://longevityharbor.com/en/watch/KtINDoRkNrA Calorie Restriction & Fasting: Aging, Immunity, Health Biomarkers, Stress, Genetics | Gary Church... https://i.ytimg.com/vi/KtINDoRkNrA/hqdefault.jpg Send a text (https://www.buzzsprout.com/twilio/text_messages/1535644/open_sms) About the guest: Gary Churchill, PhD is a statistician & geneticist at the Jackson Research laboratory in Maine. His lab uses a systems approach to investigate the genetics of complex biological traits in health & disease. Episode summary: Nick and Dr. Churchill discuss: his recent papers looking at the effects of caloric restriction & intermittent fasting on nearly 1,000 genetically diverse mice; how dietary restrictions affect longevity, metabolic health, immunity, and hundreds of biomarkers; the role of genetics vs. diet in aging; and more. Related episodes: • M&M #139 (https://mindandmatter.substack.com/p/metabolic-switching-fasting-ketosis?utm_source=publication-search) : Metabolic Switching, Fasting, Ketosis, Neuroplasticity, Diet & Neurodegenerative Disease *This content is never meant to serve as medical advice. *Full episode available free on Substack (https://mindandmatter.substack.com/) & YouTube (https://www.youtube.com/@MindAndMatter) . Support the show (https://mindandmatter.substack.com/p/how-to-support-mind-and-matter) Health Products by M&M Partners: • SporesMD (https://sporesmd.com/?ref=mindmatter) : Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. • Lumen device (https://www.lumen.me/shop?fid=8731&discount=MINDMATTER) : Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. • AquaTru (https://aquatruwater.com/?oid2=50&affid2=11307) : Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. • Seed Oil Scout (https://download.seedoilscout.com/xhLZ?af_xp=custom&pid=affiliate&c=Nick%20Jikomes) : Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. https://www.youtube-nocookie.com/embed/KtINDoRkNrA 3523 2025-11-04T01:19:04.000Z 2026-10-22T18:32:09.911Z https://longevityharbor.com/de/watch/KtINDoRkNrA Calorie Restriction & Fasting: Aging, Immunity, Health Biomarkers, Stress, Genetics | Gary Church... https://i.ytimg.com/vi/KtINDoRkNrA/hqdefault.jpg Send a text (https://www.buzzsprout.com/twilio/text_messages/1535644/open_sms) About the guest: Gary Churchill, PhD is a statistician & geneticist at the Jackson Research laboratory in Maine. His lab uses a systems approach to investigate the genetics of complex biological traits in health & disease. Episode summary: Nick and Dr. Churchill discuss: his recent papers looking at the effects of caloric restriction & intermittent fasting on nearly 1,000 genetically diverse mice; how dietary restrictions affect longevity, metabolic health, immunity, and hundreds of biomarkers; the role of genetics vs. diet in aging; and more. Related episodes: • M&M #139 (https://mindandmatter.substack.com/p/metabolic-switching-fasting-ketosis?utm_source=publication-search) : Metabolic Switching, Fasting, Ketosis, Neuroplasticity, Diet & Neurodegenerative Disease *This content is never meant to serve as medical advice. *Full episode available free on Substack (https://mindandmatter.substack.com/) & YouTube (https://www.youtube.com/@MindAndMatter) . Support the show (https://mindandmatter.substack.com/p/how-to-support-mind-and-matter) Health Products by M&M Partners: • SporesMD (https://sporesmd.com/?ref=mindmatter) : Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. • Lumen device (https://www.lumen.me/shop?fid=8731&discount=MINDMATTER) : Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. • AquaTru (https://aquatruwater.com/?oid2=50&affid2=11307) : Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. • Seed Oil Scout (https://download.seedoilscout.com/xhLZ?af_xp=custom&pid=affiliate&c=Nick%20Jikomes) : Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. https://www.youtube-nocookie.com/embed/KtINDoRkNrA 3523 2025-11-04T01:19:04.000Z 2026-10-22T18:32:09.911Z https://longevityharbor.com/en/watch/KtP42zuplS4 Gesunde Ernährung: Lässt sich das Altern aufhalten? https://i.ytimg.com/vi/KtP42zuplS4/hqdefault.jpg Kann eine gesunde Ernährung tatsächlich dazu beitragen, den Alterungsprozess zu verlangsamen? Existieren wissenschaftliche Nachweise dafür? Und was genau bedeutet eigentlich Altern? Fragen, die die Menschheit wohl schon seit jeher beschäftigen. Irit wirft in dieser Folge DatenDurchblick einen Blick auf diese Thematik und versucht, etwas Klarheit in diese Fragen zu bringen. Mehr spannende Podcasts von Thieme findest du hier: https://thieme.com/podcast https://www.youtube-nocookie.com/embed/KtP42zuplS4 306 2024-07-03T18:15:09.000Z 2026-10-22T18:43:10.789Z https://longevityharbor.com/de/watch/KtP42zuplS4 Gesunde Ernährung: Lässt sich das Altern aufhalten? https://i.ytimg.com/vi/KtP42zuplS4/hqdefault.jpg Kann eine gesunde Ernährung tatsächlich dazu beitragen, den Alterungsprozess zu verlangsamen? Existieren wissenschaftliche Nachweise dafür? Und was genau bedeutet eigentlich Altern? Fragen, die die Menschheit wohl schon seit jeher beschäftigen. Irit wirft in dieser Folge DatenDurchblick einen Blick auf diese Thematik und versucht, etwas Klarheit in diese Fragen zu bringen. Mehr spannende Podcasts von Thieme findest du hier: https://thieme.com/podcast https://www.youtube-nocookie.com/embed/KtP42zuplS4 306 2024-07-03T18:15:09.000Z 2026-10-22T18:43:10.789Z https://longevityharbor.com/en/watch/KzYEcJcxYH0 Senolitics with Dr. Iman Azimi https://i.ytimg.com/vi/KzYEcJcxYH0/hqdefault.jpg We often talk about aging as if it’s a single process—but what if the real story is hidden in cellular diversity? In this episode, Dr. Iman Azimi joins Dr. Raghav Sehgal and Dr. Macsue Jacques to unpack his groundbreaking work on senescent cells using single-cell fluorescence imaging. From the failures of current senolytics to the promise of precision approaches, we take you inside the next frontier of aging research. 👉 Topics covered in this episode: • The mosaic of senescent cell states • Why conventional biomarkers like p21 and SA-β-gal may be misleading • Rapamycin's unexpected selectivity • Building smarter, more personalized interventions 🎙 Subscribe to Decoding Longevity for more episodes exploring the science of healthspan and biological aging. #Senolytics #LongevityPodcast #DrImanAzimi #AgingResearch #DecodingLongevity #Healthspan #AgingBiomarkers https://www.youtube-nocookie.com/embed/KzYEcJcxYH0 1061 2025-07-31T06:40:33.000Z 2026-10-22T18:43:13.548Z https://longevityharbor.com/de/watch/KzYEcJcxYH0 Senolitics with Dr. Iman Azimi https://i.ytimg.com/vi/KzYEcJcxYH0/hqdefault.jpg We often talk about aging as if it’s a single process—but what if the real story is hidden in cellular diversity? In this episode, Dr. Iman Azimi joins Dr. Raghav Sehgal and Dr. Macsue Jacques to unpack his groundbreaking work on senescent cells using single-cell fluorescence imaging. From the failures of current senolytics to the promise of precision approaches, we take you inside the next frontier of aging research. 👉 Topics covered in this episode: • The mosaic of senescent cell states • Why conventional biomarkers like p21 and SA-β-gal may be misleading • Rapamycin's unexpected selectivity • Building smarter, more personalized interventions 🎙 Subscribe to Decoding Longevity for more episodes exploring the science of healthspan and biological aging. #Senolytics #LongevityPodcast #DrImanAzimi #AgingResearch #DecodingLongevity #Healthspan #AgingBiomarkers https://www.youtube-nocookie.com/embed/KzYEcJcxYH0 1061 2025-07-31T06:40:33.000Z 2026-10-22T18:43:13.548Z https://longevityharbor.com/en/watch/L02DoJrhaQA Epigenetik & biologisches Alter: Was sagt der Wert aus? | Aku https://i.ytimg.com/vi/L02DoJrhaQA/hqdefault.jpg Gleiche Buchstaben, andere Markierungen: Aku erklärt das Methylom und zeigt, warum zwei epigenetische Altersschätzungen nicht automatisch vergleichbar sind. Vertiefung und dein nächster Schritt: https://ich.center/omics/epigenom/ Video mit Lesefassung: https://ich.center/videos/epigenetik-methylom/ Das nimmst du mit: Du unterscheidest DNA-Sequenz, epigenetische Markierungen und eine daraus berechnete Altersschätzung. Alle acht Videos und Übungen mit Aku: https://ich.center/lernen/ ich.center verbindet personalisierte Diagnostik mit einer wissenschaftlichen Einordnung deiner Ergebnisse. Mehr über die Zusammenarbeit: https://ich.center/zusammenarbeit/ Die Körperstadt ist ein vereinfachtes Lernbild. Dieses Video vermittelt Grundlagen und ersetzt keine persönliche ärztliche Beratung. #ichcenter #Multiomics #Gesundheitswissen https://www.youtube-nocookie.com/embed/L02DoJrhaQA 121 2026-10-21T14:27:55.000Z 2026-10-22T17:11:30.660Z https://longevityharbor.com/de/watch/L02DoJrhaQA Epigenetik & biologisches Alter: Was sagt der Wert aus? | Aku https://i.ytimg.com/vi/L02DoJrhaQA/hqdefault.jpg Gleiche Buchstaben, andere Markierungen: Aku erklärt das Methylom und zeigt, warum zwei epigenetische Altersschätzungen nicht automatisch vergleichbar sind. Vertiefung und dein nächster Schritt: https://ich.center/omics/epigenom/ Video mit Lesefassung: https://ich.center/videos/epigenetik-methylom/ Das nimmst du mit: Du unterscheidest DNA-Sequenz, epigenetische Markierungen und eine daraus berechnete Altersschätzung. Alle acht Videos und Übungen mit Aku: https://ich.center/lernen/ ich.center verbindet personalisierte Diagnostik mit einer wissenschaftlichen Einordnung deiner Ergebnisse. Mehr über die Zusammenarbeit: https://ich.center/zusammenarbeit/ Die Körperstadt ist ein vereinfachtes Lernbild. Dieses Video vermittelt Grundlagen und ersetzt keine persönliche ärztliche Beratung. #ichcenter #Multiomics #Gesundheitswissen https://www.youtube-nocookie.com/embed/L02DoJrhaQA 121 2026-10-21T14:27:55.000Z 2026-10-22T17:11:30.660Z https://longevityharbor.com/en/watch/L2rWWauz6Ys Poster on sleep duration, sleep problems and epigenetic age acceleration in youth https://i.ytimg.com/vi/L2rWWauz6Ys/hqdefault.jpg A conference poster description says Joshua Goode and co-authors examined whether sleep duration and sleep problems predict epigenetic age acceleration in youth. The description gives no results. https://www.youtube-nocookie.com/embed/L2rWWauz6Ys 96 2026-05-15T18:32:50.000Z 2026-10-23T00:45:41.803Z https://longevityharbor.com/de/watch/L2rWWauz6Ys Poster zu Schlafdauer, Schlafproblemen und epigenetischer Altersbeschleunigung bei Jugendlichen https://i.ytimg.com/vi/L2rWWauz6Ys/hqdefault.jpg Eine Poster-Beschreibung einer Konferenz berichtet, dass Joshua Goode und Mitautorinnen und -autoren untersuchten, ob Schlafdauer und Schlafprobleme epigenetische Altersbeschleunigung bei Jugendlichen vorhersagen. Ergebnisse nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/L2rWWauz6Ys 96 2026-05-15T18:32:50.000Z 2026-10-23T00:45:41.803Z https://longevityharbor.com/en/watch/L7eqJICP7Jo Dog Aging Project scientist describes epigenetic clocks and faster aging in larger dog breeds https://i.ytimg.com/vi/L7eqJICP7Jo/hqdefault.jpg In this video description, a Dog Aging Project scientist presents DNA methylation clocks for dogs, steeper epigenetic aging slopes in larger breeds, and dysregulated transposable elements, while noting limits of consumer tests. https://www.youtube-nocookie.com/embed/L7eqJICP7Jo 2496 2026-07-28T04:00:18.000Z 2026-10-22T23:20:43.976Z https://longevityharbor.com/de/watch/L7eqJICP7Jo Wissenschaftler des Dog Aging Project beschreibt epigenetische Uhren und schnelleres Altern bei größ https://i.ytimg.com/vi/L7eqJICP7Jo/hqdefault.jpg In dieser Videobeschreibung stellt ein Wissenschaftler des Dog Aging Project DNA-Methylierungsuhren für Hunde vor, steilere epigenetische Alterungskurven bei größeren Rassen und dysregulierte Transposons – und nennt Grenzen kommerzieller Tests. https://www.youtube-nocookie.com/embed/L7eqJICP7Jo 2496 2026-07-28T04:00:18.000Z 2026-10-22T23:20:43.976Z https://longevityharbor.com/en/watch/L9RayuKoh60 Video description: four methods for measuring biological age https://i.ytimg.com/vi/L9RayuKoh60/hqdefault.jpg The description says biological age can differ from calendar age and presents four methods for measuring it: epigenetic clocks, a blood panel, a sit-to-stand test and VO2max. https://www.youtube-nocookie.com/embed/L9RayuKoh60 674 2026-06-04T20:38:57.000Z 2026-10-23T00:07:14.706Z https://longevityharbor.com/de/watch/L9RayuKoh60 Videobeschreibung: vier Methoden zur Messung des biologischen Alters https://i.ytimg.com/vi/L9RayuKoh60/hqdefault.jpg Laut Beschreibung kann das biologische Alter vom Kalenderalter abweichen; vorgestellt werden vier Messmethoden: epigenetische Uhren, ein Blutpanel, ein Aufsteh-Test und VO2max. https://www.youtube-nocookie.com/embed/L9RayuKoh60 674 2026-06-04T20:38:57.000Z 2026-10-23T00:07:14.706Z https://longevityharbor.com/en/watch/LCL0aEtvpNA Video description: bedtime between 9 and 10 PM discussed for adults over 70 https://i.ytimg.com/vi/LCL0aEtvpNA/hqdefault.jpg The description says this science-based documentary explores how the biological clock changes with age and why a consistent bedtime between 9:00 and 10:00 PM may be worth considering after 70. It also lists evening habits and practical sleep habits. https://www.youtube-nocookie.com/embed/LCL0aEtvpNA 1311 2026-10-04T12:00:20.000Z 2026-10-22T21:27:59.981Z https://longevityharbor.com/de/watch/LCL0aEtvpNA Videobeschreibung: Schlafenszeit zwischen 21 und 22 Uhr für Erwachsene über 70 erörtert https://i.ytimg.com/vi/LCL0aEtvpNA/hqdefault.jpg Laut Beschreibung untersucht diese wissenschaftsbasierte Dokumentation, wie sich die innere Uhr mit dem Alter verändert und warum eine gleichbleibende Schlafenszeit zwischen 21:00 und 22:00 Uhr nach 70 erwogen werden könnte. Zudem nennt sie Abendgewohnheiten und praktische Schlafgewohnheiten. https://www.youtube-nocookie.com/embed/LCL0aEtvpNA 1311 2026-10-04T12:00:20.000Z 2026-10-22T21:27:59.981Z https://longevityharbor.com/en/watch/LCPvF-SlZIU Transforming Our Understanding of Healthcare Through Geroscience | 11 - LS #4 https://i.ytimg.com/vi/LCPvF-SlZIU/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Everything we talk about on The Optispan Podcast has geroscience at its root, so we decided to make an episode about it. Geroscience is the study of the mechanisms connecting biological aging with disease and disability. The term first appeared in the scientific literature around 2008, and its use has steadily increased since as researchers have discovered more about the aging process and its impact on our health. While it's clear that aging biology is at the root of the diseases and disabilities that most people get sick with and die from in their later years, it's been a challenge to get the field the traction and support that other fields enjoy, in part because we are used to a "disease care" model of waiting until people get sick and only then addressing their symptoms and/or curing their disease. In this episode, Matt dives into how geroscience underpins the way we age, entrenched cultures in industries from drug development to insurance to regulation, and why he's excited to create a geroscience-inspired disruption in the medical and healthcare industries. 0:00 Trailer 0:36 Introduction/defining geroscience 2:21 The connection between aging biology and disease 5:32 The Hallmarks of Aging 7:10 Geroscience is still underfunded and understudied compared to other areas of biomedical research 9:52 The impact on health- and lifespan of curing major diseases like cancer and heart disease 13:41 An economic argument for tackling the biological aging process 14:57 Why hasn't geroscience research received more recognition and support? 17:48 How things are changing in for-profit, non-profit, and political spaces Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The https://www.youtube-nocookie.com/embed/LCPvF-SlZIU 1331 2024-03-04T15:00:26.000Z 2026-10-22T17:43:40.128Z https://longevityharbor.com/de/watch/LCPvF-SlZIU Transforming Our Understanding of Healthcare Through Geroscience | 11 - LS #4 https://i.ytimg.com/vi/LCPvF-SlZIU/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Everything we talk about on The Optispan Podcast has geroscience at its root, so we decided to make an episode about it. Geroscience is the study of the mechanisms connecting biological aging with disease and disability. The term first appeared in the scientific literature around 2008, and its use has steadily increased since as researchers have discovered more about the aging process and its impact on our health. While it's clear that aging biology is at the root of the diseases and disabilities that most people get sick with and die from in their later years, it's been a challenge to get the field the traction and support that other fields enjoy, in part because we are used to a "disease care" model of waiting until people get sick and only then addressing their symptoms and/or curing their disease. In this episode, Matt dives into how geroscience underpins the way we age, entrenched cultures in industries from drug development to insurance to regulation, and why he's excited to create a geroscience-inspired disruption in the medical and healthcare industries. 0:00 Trailer 0:36 Introduction/defining geroscience 2:21 The connection between aging biology and disease 5:32 The Hallmarks of Aging 7:10 Geroscience is still underfunded and understudied compared to other areas of biomedical research 9:52 The impact on health- and lifespan of curing major diseases like cancer and heart disease 13:41 An economic argument for tackling the biological aging process 14:57 Why hasn't geroscience research received more recognition and support? 17:48 How things are changing in for-profit, non-profit, and political spaces Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The https://www.youtube-nocookie.com/embed/LCPvF-SlZIU 1331 2024-03-04T15:00:26.000Z 2026-10-22T17:43:40.128Z https://longevityharbor.com/en/watch/LH5eFR6XR0o Video description: seven foods claimed to support muscles after 60 https://i.ytimg.com/vi/LH5eFR6XR0o/hqdefault.jpg The description says seven foods supply valuable nutrients to support muscle health and counter age-related muscle loss after 60; it names no foods and reports no results. https://www.youtube-nocookie.com/embed/LH5eFR6XR0o 1158 2026-09-28T08:00:25.000Z 2026-10-22T21:41:11.971Z https://longevityharbor.com/de/watch/LH5eFR6XR0o Videobeschreibung: sieben Lebensmittel für Muskeln nach 60 https://i.ytimg.com/vi/LH5eFR6XR0o/hqdefault.jpg Die Beschreibung nennt sieben Lebensmittel mit wertvollen Nährstoffen für die Muskelgesundheit und gegen altersassoziierten Muskelabbau nach 60; sie nennt keine Lebensmittel und keine Ergebnisse. https://www.youtube-nocookie.com/embed/LH5eFR6XR0o 1158 2026-09-28T08:00:25.000Z 2026-10-22T21:41:11.971Z https://longevityharbor.com/en/watch/LHPi5JQ3GJs Unlocking the Secrets of Ageing - Part Two | The ATP Project 418 https://i.ytimg.com/vi/LHPi5JQ3GJs/hqdefault.jpg Unlocking the Secrets of Ageing: Part 2 - Longevity | The ATP Project 418 Join Nic and Steve as they embark on a journey into the world of ageing and longevity. This is part two of a two-part series. Delving deep into the science, they unravel the mysteries behind why we age and unveil practical strategies to turn back the clock. Discover how lifestyle changes can significantly impact the ageing process, and learn how to embrace a more vibrant and youthful you! As always, this information is not designed to diagnose, treat, prevent or cure any condition and is for information purposes only - please discuss any information in this podcast with your healthcare professional before making any changes to your current lifestyle. Part one can be found here - https://youtu.be/L4Z5RzhnBIw Check out ATP Science's range of products at our online store - https://bit.ly/3Qp1dQz 00:00:00 – Longevity – How do you live longer 00::02:39 – Health span v life span 00:04:18 – Obesity – and longevity 00:11:48 – The wellness scale 00:12:28 – The data on lifespan 00:15:40 – Homesis – whatever doesn’t kill you makes you stronger? 00:18:31 – Mitochondria and ageing? 00:27:07 – How do you look after your mitochondria? 00:29:16 – mTOR - Mammalian target of rapamycin and longevity 00:35:36 – Longevity hacks – what can I take? 00:42:47 – Nrf2 activation – how to activate and why it is important! 00:44:47 – NADH - nicotinamide adenine dinucleotide (NAD) + hydrogen (H) 00:51:38 – longevity genes 00:57:25 – Telomeres – increase length? 01:04:10 - Senescence cells – zombie cells! 01:07:48 – What you should be doing and supplementing? REFEREENCES Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies https://pubmed.ncbi.nlm.nih.gov/32202443/ Ng QX, De Deyn MLZQ, Loke W, Foo NX, Chan HW, Yeo WS. Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies. J Diet Suppl. 2021;18(2):169-182. doi: 10.1080/19390211.2020.1739187. Epub 2020 Mar 23. PMID: 32202443. PMID: 32 https://www.youtube-nocookie.com/embed/LHPi5JQ3GJs 4679 2023-11-07T01:15:09.000Z 2026-10-22T19:04:37.504Z https://longevityharbor.com/de/watch/LHPi5JQ3GJs Unlocking the Secrets of Ageing - Part Two | The ATP Project 418 https://i.ytimg.com/vi/LHPi5JQ3GJs/hqdefault.jpg Unlocking the Secrets of Ageing: Part 2 - Longevity | The ATP Project 418 Join Nic and Steve as they embark on a journey into the world of ageing and longevity. This is part two of a two-part series. Delving deep into the science, they unravel the mysteries behind why we age and unveil practical strategies to turn back the clock. Discover how lifestyle changes can significantly impact the ageing process, and learn how to embrace a more vibrant and youthful you! As always, this information is not designed to diagnose, treat, prevent or cure any condition and is for information purposes only - please discuss any information in this podcast with your healthcare professional before making any changes to your current lifestyle. Part one can be found here - https://youtu.be/L4Z5RzhnBIw Check out ATP Science's range of products at our online store - https://bit.ly/3Qp1dQz 00:00:00 – Longevity – How do you live longer 00::02:39 – Health span v life span 00:04:18 – Obesity – and longevity 00:11:48 – The wellness scale 00:12:28 – The data on lifespan 00:15:40 – Homesis – whatever doesn’t kill you makes you stronger? 00:18:31 – Mitochondria and ageing? 00:27:07 – How do you look after your mitochondria? 00:29:16 – mTOR - Mammalian target of rapamycin and longevity 00:35:36 – Longevity hacks – what can I take? 00:42:47 – Nrf2 activation – how to activate and why it is important! 00:44:47 – NADH - nicotinamide adenine dinucleotide (NAD) + hydrogen (H) 00:51:38 – longevity genes 00:57:25 – Telomeres – increase length? 01:04:10 - Senescence cells – zombie cells! 01:07:48 – What you should be doing and supplementing? REFEREENCES Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies https://pubmed.ncbi.nlm.nih.gov/32202443/ Ng QX, De Deyn MLZQ, Loke W, Foo NX, Chan HW, Yeo WS. Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies. J Diet Suppl. 2021;18(2):169-182. doi: 10.1080/19390211.2020.1739187. Epub 2020 Mar 23. PMID: 32202443. PMID: 32 https://www.youtube-nocookie.com/embed/LHPi5JQ3GJs 4679 2023-11-07T01:15:09.000Z 2026-10-22T19:04:37.504Z https://longevityharbor.com/en/watch/LJ1pIgl542U Diet and Caloric Restriction for Longevity—The Monkey Trials https://i.ytimg.com/vi/LJ1pIgl542U/hqdefault.jpg How can we make sense of the disparate results from the four primate studies on caloric restriction and lifespan? Here are some of my previous videos on dietary restriction if you’re interested in taking a deeper dive: • The Benefits of Caloric Restriction Without the Actual Restricting (https://nutritionfacts.org/video/the-benefits-of-caloric-restriction-without-the-actual-restricting/) • Caloric Restriction vs. Animal Protein Restriction (https://nutritionfacts.org/video/caloric-restriction-vs-animal-protein-restriction/) • Caloric Restriction vs. Plant-Based Diets (https://nutritionfacts.org/video/caloric-restriction-vs-plant-based-diets/) • The Benefits of Calorie Restriction for Longevity (https://nutritionfacts.org/video/the-benefits-of-calorie-restriction-for-longevity/) • Potential Pitfalls of Calorie Restriction (https://nutritionfacts.org/video/potential-pitfalls-of-calorie-restriction/) My new book, How Not to Age (https://nutritionfacts.org/book/how-not-to-age/), is all about living a longer life, and you can get your copy now at your local public library or wherever books are sold. If you haven’t seen them yet, check out the book trailer (https://nutritionfacts.org/video/book-trailer-for-how-not-to-age) and my new presentation (https://nutritionfacts.org/video/how-not-to-age-live-presentation/). (As always, all proceeds I receive from all (https://nutritionfacts.org/books/) of my books are donated to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/diet-and-caloric-restriction-for-longevity-the-monkey-trials and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/diet-and-caloric-restriction-for-longevity-the-monkey-trials. You’ll also find a transcript and acknowledgement https://www.youtube-nocookie.com/embed/LJ1pIgl542U 328 2024-01-17T12:59:51.000Z 2026-10-22T17:43:38.411Z https://longevityharbor.com/de/watch/LJ1pIgl542U Diet and Caloric Restriction for Longevity—The Monkey Trials https://i.ytimg.com/vi/LJ1pIgl542U/hqdefault.jpg How can we make sense of the disparate results from the four primate studies on caloric restriction and lifespan? Here are some of my previous videos on dietary restriction if you’re interested in taking a deeper dive: • The Benefits of Caloric Restriction Without the Actual Restricting (https://nutritionfacts.org/video/the-benefits-of-caloric-restriction-without-the-actual-restricting/) • Caloric Restriction vs. Animal Protein Restriction (https://nutritionfacts.org/video/caloric-restriction-vs-animal-protein-restriction/) • Caloric Restriction vs. Plant-Based Diets (https://nutritionfacts.org/video/caloric-restriction-vs-plant-based-diets/) • The Benefits of Calorie Restriction for Longevity (https://nutritionfacts.org/video/the-benefits-of-calorie-restriction-for-longevity/) • Potential Pitfalls of Calorie Restriction (https://nutritionfacts.org/video/potential-pitfalls-of-calorie-restriction/) My new book, How Not to Age (https://nutritionfacts.org/book/how-not-to-age/), is all about living a longer life, and you can get your copy now at your local public library or wherever books are sold. If you haven’t seen them yet, check out the book trailer (https://nutritionfacts.org/video/book-trailer-for-how-not-to-age) and my new presentation (https://nutritionfacts.org/video/how-not-to-age-live-presentation/). (As always, all proceeds I receive from all (https://nutritionfacts.org/books/) of my books are donated to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/diet-and-caloric-restriction-for-longevity-the-monkey-trials and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/diet-and-caloric-restriction-for-longevity-the-monkey-trials. You’ll also find a transcript and acknowledgement https://www.youtube-nocookie.com/embed/LJ1pIgl542U 328 2024-01-17T12:59:51.000Z 2026-10-22T17:43:38.411Z https://longevityharbor.com/en/watch/LKzDsmdxen8 Nutrition Professor: How inflammation could age you | Philip Calder https://i.ytimg.com/vi/LKzDsmdxen8/hqdefault.jpg Learn how your body responds to food. Take our FREE quiz 👉 http://zoe.com/podcast 🌱 Try our new plant based wholefood supplement - Daily 30 https://bit.ly/ZOEDaily30 *Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system Inflammation is a complicated topic. Short-term inflammation plays an essential role in fighting infections and healing injuries. But too much inflammation can be a catalyst for chronic ailments, like heart disease, type 2 diabetes, autoimmune disorders, rheumatoid arthritis, and obesity. What we eat can influence our inflammatory responses and contribute to chronic, low-grade inflammation. In today’s episode, Prof. Philip Calder helps us understand the science behind inflammation, how it impacts our health and what food has to do with it. Philip is head of the School of Human Development and Health, as well as a Professor of Nutritional Immunology, in the Faculty of Medicine at the University of Southampton. He’s also an internationally recognised researcher on the metabolism and functionality of fatty acids. His work focuses on the roles of omega-3 fatty acids and the influence of diet and nutrients on immune and inflammatory responses. Timecodes: 00:00 Introduction 01:10 Quickfire questions 03:00 The role of inflammation in immunity 05:40 Chronic inflammation and disease 08:49 How to measure inflammation 10:14 Should you worry about low-grade inflammation? 12:54 What causes blood vessel inflammation? 16:03 What creates the narrowing of blood vessels? 18:21 How inflammation can cause blood clots, heart attacks and strokes 20:13 Inflammation and aging 22:41 Inflammation and lifestyle factors 26:11 Obesity and inflammation 29:48 Muscle loss and inflammation (sarcopenia) 31:56 The impact of meals, sugar and fats on inflammation 36:04 Impact of diet inflammation 37:11 Why we all respond to food differently 42:25 What are omega-3s? 43:45 Anti-inflammatory foods 46:08 Health benefits of omega-3 fatty acids 48:24 Challeng https://www.youtube-nocookie.com/embed/LKzDsmdxen8 3683 2024-05-16T15:06:00.000Z 2026-10-22T18:43:11.851Z https://longevityharbor.com/de/watch/LKzDsmdxen8 Nutrition Professor: How inflammation could age you | Philip Calder https://i.ytimg.com/vi/LKzDsmdxen8/hqdefault.jpg Learn how your body responds to food. Take our FREE quiz 👉 http://zoe.com/podcast 🌱 Try our new plant based wholefood supplement - Daily 30 https://bit.ly/ZOEDaily30 *Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system Inflammation is a complicated topic. Short-term inflammation plays an essential role in fighting infections and healing injuries. But too much inflammation can be a catalyst for chronic ailments, like heart disease, type 2 diabetes, autoimmune disorders, rheumatoid arthritis, and obesity. What we eat can influence our inflammatory responses and contribute to chronic, low-grade inflammation. In today’s episode, Prof. Philip Calder helps us understand the science behind inflammation, how it impacts our health and what food has to do with it. Philip is head of the School of Human Development and Health, as well as a Professor of Nutritional Immunology, in the Faculty of Medicine at the University of Southampton. He’s also an internationally recognised researcher on the metabolism and functionality of fatty acids. His work focuses on the roles of omega-3 fatty acids and the influence of diet and nutrients on immune and inflammatory responses. Timecodes: 00:00 Introduction 01:10 Quickfire questions 03:00 The role of inflammation in immunity 05:40 Chronic inflammation and disease 08:49 How to measure inflammation 10:14 Should you worry about low-grade inflammation? 12:54 What causes blood vessel inflammation? 16:03 What creates the narrowing of blood vessels? 18:21 How inflammation can cause blood clots, heart attacks and strokes 20:13 Inflammation and aging 22:41 Inflammation and lifestyle factors 26:11 Obesity and inflammation 29:48 Muscle loss and inflammation (sarcopenia) 31:56 The impact of meals, sugar and fats on inflammation 36:04 Impact of diet inflammation 37:11 Why we all respond to food differently 42:25 What are omega-3s? 43:45 Anti-inflammatory foods 46:08 Health benefits of omega-3 fatty acids 48:24 Challeng https://www.youtube-nocookie.com/embed/LKzDsmdxen8 3683 2024-05-16T15:06:00.000Z 2026-10-22T18:43:11.851Z https://longevityharbor.com/en/watch/LMyPkPhKJIA 10 Essential Nutrition Tips for Healthy Aging (From The Geriatric Dietitian) https://i.ytimg.com/vi/LMyPkPhKJIA/hqdefault.jpg Eating well is one of the most powerful ways to stay strong, independent, and healthy as you age! In this video, I share 10 essential nutrition tips for healthy aging — from staying hydrated and getting enough protein to protecting your bones and enjoying your meals. These tips come straight from my free handout, designed to help older adults fuel their bodies and thrive at any age. 💧 Download your free guide: 👉 https://thegeriatricdietitian.myflodesk.com/ 🌐 Learn more on my website: 👉 https://thegeriatricdietitian.com/ ❤️ If this video helps you, please like, subscribe, and share it with a loved one! #HealthyAging #SeniorNutrition #TheGeriatricDietitian https://www.youtube-nocookie.com/embed/LMyPkPhKJIA 876 2025-10-06T03:21:15.000Z 2026-10-22T18:43:11.733Z https://longevityharbor.com/de/watch/LMyPkPhKJIA 10 Essential Nutrition Tips for Healthy Aging (From The Geriatric Dietitian) https://i.ytimg.com/vi/LMyPkPhKJIA/hqdefault.jpg Eating well is one of the most powerful ways to stay strong, independent, and healthy as you age! In this video, I share 10 essential nutrition tips for healthy aging — from staying hydrated and getting enough protein to protecting your bones and enjoying your meals. These tips come straight from my free handout, designed to help older adults fuel their bodies and thrive at any age. 💧 Download your free guide: 👉 https://thegeriatricdietitian.myflodesk.com/ 🌐 Learn more on my website: 👉 https://thegeriatricdietitian.com/ ❤️ If this video helps you, please like, subscribe, and share it with a loved one! #HealthyAging #SeniorNutrition #TheGeriatricDietitian https://www.youtube-nocookie.com/embed/LMyPkPhKJIA 876 2025-10-06T03:21:15.000Z 2026-10-22T18:43:11.733Z https://longevityharbor.com/en/watch/LOyDOwt4sr0 Rapamycin, senolytics, genetic engineering... Which would be the best antiaging intervention? EP.1 https://i.ytimg.com/vi/LOyDOwt4sr0/hqdefault.jpg Welcome to our latest video featuring insightful interviews conducted at the 4th Timepie Longevity Forum. In this engaging segment, we sit down with distinguished scholars to discuss the most promising anti-aging interventions anticipated in the coming decade. From microbiome interventions to senolytics, epigenetic interventions, rapamycin, and beyond, our experts delve into the forefront of research and development in the field of longevity. Join us as we explore the potential breakthroughs that hold promise for extending human lifespan and enhancing quality of life. For more stuff on anti-aging and longevity Twitter: https://twitter.com/TimePieChina Linkedin: https://www.linkedin.com/company/timepie/ -------------------------------------------------------------------------------------------------------- TimePie is a science popularization platform based on Fudan University alumni, with over 600,000 subscribers in China. Our mission is to help people live longer and age healthier. This channel is where you can find fresh information from the anti-aging industry and exclusive lectures delivered by famous scholars and biohackers. Stay tuned for more updates from TimePie. #longevity #aging #antiaging #lifespan #intervention #gut https://www.youtube-nocookie.com/embed/LOyDOwt4sr0 198 2024-02-12T10:00:12.000Z 2026-10-22T19:04:40.836Z https://longevityharbor.com/de/watch/LOyDOwt4sr0 Rapamycin, senolytics, genetic engineering... Which would be the best antiaging intervention? EP.1 https://i.ytimg.com/vi/LOyDOwt4sr0/hqdefault.jpg Welcome to our latest video featuring insightful interviews conducted at the 4th Timepie Longevity Forum. In this engaging segment, we sit down with distinguished scholars to discuss the most promising anti-aging interventions anticipated in the coming decade. From microbiome interventions to senolytics, epigenetic interventions, rapamycin, and beyond, our experts delve into the forefront of research and development in the field of longevity. Join us as we explore the potential breakthroughs that hold promise for extending human lifespan and enhancing quality of life. For more stuff on anti-aging and longevity Twitter: https://twitter.com/TimePieChina Linkedin: https://www.linkedin.com/company/timepie/ -------------------------------------------------------------------------------------------------------- TimePie is a science popularization platform based on Fudan University alumni, with over 600,000 subscribers in China. Our mission is to help people live longer and age healthier. This channel is where you can find fresh information from the anti-aging industry and exclusive lectures delivered by famous scholars and biohackers. Stay tuned for more updates from TimePie. #longevity #aging #antiaging #lifespan #intervention #gut https://www.youtube-nocookie.com/embed/LOyDOwt4sr0 198 2024-02-12T10:00:12.000Z 2026-10-22T19:04:40.836Z https://longevityharbor.com/en/watch/LRDSRa4GiV0 Lange fit bis ins Alter – Experte: Die einzige Lösung gegen Muskelschwund https://i.ytimg.com/vi/LRDSRa4GiV0/hqdefault.jpg Altersbedingter Muskelabbau kommt langsam, aber stetig. Im Video erklärt Professor Ingo Froböse, mit welchen Tipps und Tricks Sie auch im Alter fit bleiben. #fragmich #Osteoporose #knochenschwund #knochen #gesundheit #sports #sport Unser t-online-YouTube-Kanal versorgt Sie mit Nachrichten zu allen wichtigen gesellschaftlichen Themen, Recherchen, Reportagen und eigenen Interviews. Auch Erklärvideos zu Klima, Inflation, Nachhaltigkeit oder Finanzen liegen uns am Herzen. Hier finden Sie uns: t-online Website: https://www.t-online.de/ Unsere Videoseite: https://www.t-online.de/tv/ Instagram: https://www.instagram.com/tonline.de/ Facebook: https://www.facebook.com/tonline Twitter: https://twitter.com/tonline Spotify Tagesanbruch: https://spoti.fi/3AclqRx Spotify Grünes Licht https://open.spotify.com/show/6VWFTlKot1ivthUlhceSUp https://www.youtube-nocookie.com/embed/LRDSRa4GiV0 411 2023-03-19T13:58:04.000Z 2026-10-22T17:43:36.011Z https://longevityharbor.com/de/watch/LRDSRa4GiV0 Lange fit bis ins Alter – Experte: Die einzige Lösung gegen Muskelschwund https://i.ytimg.com/vi/LRDSRa4GiV0/hqdefault.jpg Altersbedingter Muskelabbau kommt langsam, aber stetig. Im Video erklärt Professor Ingo Froböse, mit welchen Tipps und Tricks Sie auch im Alter fit bleiben. #fragmich #Osteoporose #knochenschwund #knochen #gesundheit #sports #sport Unser t-online-YouTube-Kanal versorgt Sie mit Nachrichten zu allen wichtigen gesellschaftlichen Themen, Recherchen, Reportagen und eigenen Interviews. Auch Erklärvideos zu Klima, Inflation, Nachhaltigkeit oder Finanzen liegen uns am Herzen. Hier finden Sie uns: t-online Website: https://www.t-online.de/ Unsere Videoseite: https://www.t-online.de/tv/ Instagram: https://www.instagram.com/tonline.de/ Facebook: https://www.facebook.com/tonline Twitter: https://twitter.com/tonline Spotify Tagesanbruch: https://spoti.fi/3AclqRx Spotify Grünes Licht https://open.spotify.com/show/6VWFTlKot1ivthUlhceSUp https://www.youtube-nocookie.com/embed/LRDSRa4GiV0 411 2023-03-19T13:58:04.000Z 2026-10-22T17:43:36.011Z https://longevityharbor.com/en/watch/LX0pAubBl9E 36 Wasay Mohammad Fasting and Brain health Study https://i.ytimg.com/vi/LX0pAubBl9E/hqdefault.jpg 36 Wasay Mohammad Fasting and Brain health Study https://www.youtube-nocookie.com/embed/LX0pAubBl9E 889 2024-02-20T12:01:37.000Z 2026-10-22T18:54:08.210Z https://longevityharbor.com/de/watch/LX0pAubBl9E 36 Wasay Mohammad Fasting and Brain health Study https://i.ytimg.com/vi/LX0pAubBl9E/hqdefault.jpg 36 Wasay Mohammad Fasting and Brain health Study https://www.youtube-nocookie.com/embed/LX0pAubBl9E 889 2024-02-20T12:01:37.000Z 2026-10-22T18:54:08.210Z https://longevityharbor.com/en/watch/LXbD_RaV2co Longevity Scientist Answers Your Questions About Rapamycin - Q&A https://i.ytimg.com/vi/LXbD_RaV2co/hqdefault.jpg 💯💯Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Timestamps: 00:00 Intro 00:37 Thoughts on Bryan Johnson stopping rapamycin 06:39 Are more antioxidants always better 09:37 Supplements versus lifestyle for longevity 12:23 Life extension compounds other than rapamycin 16:40 Matt’s controversial takes on supplements and lifestyle 28:10 My book promo 28:35 Matt’s thoughts on peptides for longevity 34:15 Thymus rejuvenation protocol 44:35 NAD IVs and Therapeutic Plasma Exchange 44:42 Does low IGF-1 support longevity 52:53 Using AI in longevity research 57:26 How much protein for longevity 01:00:18 Why is grip strength linked to longevity 01:02:05 Preserving female reproductive function 01:06:32 Slowing aging in dogs Me on Matt's podcast: https://youtu.be/3Hm3a-SWPBI Matt Kaeberlein YouTube: https://www.youtube.com/@UCSna7385c3Xg_4Too92NKMw Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Top 15 Supplements to Take: https://youtu.be/jrozJ6oMEjo?si=d0FOfgOm_BUnaMjy Shop: https://www.siimland.co/shop My Books: https://www.siimland.co/books P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first. Follow me on social media: Website: http://www.siimland.co Facebook: https://www.facebook.com/thesiimland/ Instagram: https://www.instagram.com/siimland/ Twitter: https://twitter.com/siimland https://www.youtube-nocookie.com/embed/LXbD_RaV2co 4279 2025-04-17T14:06:33.000Z 2026-10-22T19:04:40.941Z https://longevityharbor.com/de/watch/LXbD_RaV2co Longevity Scientist Answers Your Questions About Rapamycin - Q&A https://i.ytimg.com/vi/LXbD_RaV2co/hqdefault.jpg 💯💯Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Timestamps: 00:00 Intro 00:37 Thoughts on Bryan Johnson stopping rapamycin 06:39 Are more antioxidants always better 09:37 Supplements versus lifestyle for longevity 12:23 Life extension compounds other than rapamycin 16:40 Matt’s controversial takes on supplements and lifestyle 28:10 My book promo 28:35 Matt’s thoughts on peptides for longevity 34:15 Thymus rejuvenation protocol 44:35 NAD IVs and Therapeutic Plasma Exchange 44:42 Does low IGF-1 support longevity 52:53 Using AI in longevity research 57:26 How much protein for longevity 01:00:18 Why is grip strength linked to longevity 01:02:05 Preserving female reproductive function 01:06:32 Slowing aging in dogs Me on Matt's podcast: https://youtu.be/3Hm3a-SWPBI Matt Kaeberlein YouTube: https://www.youtube.com/@UCSna7385c3Xg_4Too92NKMw Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Top 15 Supplements to Take: https://youtu.be/jrozJ6oMEjo?si=d0FOfgOm_BUnaMjy Shop: https://www.siimland.co/shop My Books: https://www.siimland.co/books P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first. Follow me on social media: Website: http://www.siimland.co Facebook: https://www.facebook.com/thesiimland/ Instagram: https://www.instagram.com/siimland/ Twitter: https://twitter.com/siimland https://www.youtube-nocookie.com/embed/LXbD_RaV2co 4279 2025-04-17T14:06:33.000Z 2026-10-22T19:04:40.941Z https://longevityharbor.com/en/watch/L_EMEQOI_K4 Epigenetik einfach erklärt – Wie unser Lebensstil unsere Gene steuert - Prof. Dr. med. Jörg Spitz https://i.ytimg.com/vi/L_EMEQOI_K4/hqdefault.jpg ❗❓ Kostenloser Gesund Leben Fragebogen - 25 Fragen zu Prävention und Gesundheit ❓❗ Nutzen Sie jetzt unser gratis Online-Tool von Prof. Spitz, um Ihre derzeitige gesundheitliche Positionierung qualitativ einzuschätzen: 👉🏻 https://spitzen-praevention.com/gesund-leben/?utm_source=videobeschreibung&utm_campaign=youtube 👈🏻 ------------------------------------------------------------------------------------- Die Bedeutung einer gesunden Ernährung mit vielen frischen Lebensmitteln ist der Grundpfeiler eines verantwortungsvollen Lebensstils. Dadurch lassen sich viele Krankheiten präventiv verhindern. Zunehmend wird dabei auch die große Bedeutung von Mikronährstoffen für den menschlichen Körper deutlich. Doch warum ist das so? Nach der Entschlüsselung des menschlichen Genoms wurde klar: Die Auffassung, dass die Gene unseren Körper steuern, konnte nicht länger aufrechterhalten werden. Vielmehr wirken Umwelteinflüsse – und so vor allem auch unsere Nahrung – auf unsere Gene. Prof. Dr. med. Jörg Spitz gibt in kurzen Worten einen Einblick in das spannende wissenschaftliche Feld der Epigenetik und erklärt im Gespräch mit Sören Schumann, was Mikronährstoffe im Körper bewirken und welche wichtigen Aufgaben sie übernehmen. ------------------------------------------------------------------------------------- 📧 Hier können Sie sich für den Newsletter bei der Akademie für menschliche Medizin registrieren https://spitzen-praevention.com/newsfeed-abonnieren/?utm_source=videobeschreibung&utm_campaign=youtube 🎬📽 Weitere Videos und Vorträge auch in der digitalen Welt der AMM 📽🎬 https://digitalewelt.spitzen-praevention.com/?utm_source=videobeschreibung&utm_campaign=youtube 📖📚 Buchempfehlungen zum Thema 📚📖 https://spitzen-praevention.com/buchempfehlung/?utm_source=videobeschreibung&utm_campaign=youtube 🍇🌞 Produktempfehlungen🥑🍄 https://spitzen-praevention.com/produktempfehlungen/?utm_source=videobeschreibung&utm_campaign=youtube 🌏🤝 Netzwerkpartner 🤝🌏 https://spitzen-praevention.com/netzwerkpartner/?utm_source=vide https://www.youtube-nocookie.com/embed/L_EMEQOI_K4 326 2021-01-30T08:00:04.000Z 2026-10-22T17:11:30.661Z https://longevityharbor.com/de/watch/L_EMEQOI_K4 Epigenetik einfach erklärt – Wie unser Lebensstil unsere Gene steuert - Prof. Dr. med. Jörg Spitz https://i.ytimg.com/vi/L_EMEQOI_K4/hqdefault.jpg ❗❓ Kostenloser Gesund Leben Fragebogen - 25 Fragen zu Prävention und Gesundheit ❓❗ Nutzen Sie jetzt unser gratis Online-Tool von Prof. Spitz, um Ihre derzeitige gesundheitliche Positionierung qualitativ einzuschätzen: 👉🏻 https://spitzen-praevention.com/gesund-leben/?utm_source=videobeschreibung&utm_campaign=youtube 👈🏻 ------------------------------------------------------------------------------------- Die Bedeutung einer gesunden Ernährung mit vielen frischen Lebensmitteln ist der Grundpfeiler eines verantwortungsvollen Lebensstils. Dadurch lassen sich viele Krankheiten präventiv verhindern. Zunehmend wird dabei auch die große Bedeutung von Mikronährstoffen für den menschlichen Körper deutlich. Doch warum ist das so? Nach der Entschlüsselung des menschlichen Genoms wurde klar: Die Auffassung, dass die Gene unseren Körper steuern, konnte nicht länger aufrechterhalten werden. Vielmehr wirken Umwelteinflüsse – und so vor allem auch unsere Nahrung – auf unsere Gene. Prof. Dr. med. Jörg Spitz gibt in kurzen Worten einen Einblick in das spannende wissenschaftliche Feld der Epigenetik und erklärt im Gespräch mit Sören Schumann, was Mikronährstoffe im Körper bewirken und welche wichtigen Aufgaben sie übernehmen. ------------------------------------------------------------------------------------- 📧 Hier können Sie sich für den Newsletter bei der Akademie für menschliche Medizin registrieren https://spitzen-praevention.com/newsfeed-abonnieren/?utm_source=videobeschreibung&utm_campaign=youtube 🎬📽 Weitere Videos und Vorträge auch in der digitalen Welt der AMM 📽🎬 https://digitalewelt.spitzen-praevention.com/?utm_source=videobeschreibung&utm_campaign=youtube 📖📚 Buchempfehlungen zum Thema 📚📖 https://spitzen-praevention.com/buchempfehlung/?utm_source=videobeschreibung&utm_campaign=youtube 🍇🌞 Produktempfehlungen🥑🍄 https://spitzen-praevention.com/produktempfehlungen/?utm_source=videobeschreibung&utm_campaign=youtube 🌏🤝 Netzwerkpartner 🤝🌏 https://spitzen-praevention.com/netzwerkpartner/?utm_source=vide https://www.youtube-nocookie.com/embed/L_EMEQOI_K4 326 2021-01-30T08:00:04.000Z 2026-10-22T17:11:30.661Z https://longevityharbor.com/en/watch/LaSCk4i1tHg Video description: diet, exercise, sleep and stress may influence epigenetic aging https://i.ytimg.com/vi/LaSCk4i1tHg/hqdefault.jpg The description says Kara Fitzgerald, ND, IFMCP, explains how nutrition, exercise, sleep and stress may influence epigenetics and potentially slow biological aging, and describes her research on diet and lifestyle interventions and DNA methylation. https://www.youtube-nocookie.com/embed/LaSCk4i1tHg 3024 2026-09-16T12:00:15.000Z 2026-10-22T22:11:37.122Z https://longevityharbor.com/de/watch/LaSCk4i1tHg Videobeschreibung: Ernährung, Bewegung, Schlaf und Stress können epigenetisches Altern beeinflussen https://i.ytimg.com/vi/LaSCk4i1tHg/hqdefault.jpg Laut Beschreibung erklärt Kara Fitzgerald, ND, IFMCP, wie Ernährung, Bewegung, Schlaf und Stress die Epigenetik beeinflussen und biologisches Altern möglicherweise verlangsamen können; beschrieben wird auch ihre Forschung zu Ernährungs- und Lebensstilinterventionen und DNA-Methylierung. https://www.youtube-nocookie.com/embed/LaSCk4i1tHg 3024 2026-09-16T12:00:15.000Z 2026-10-22T22:11:37.122Z https://longevityharbor.com/en/watch/LdP319eEhX4 Video description: epigenetic clocks estimating biological age from DNA marks https://i.ytimg.com/vi/LdP319eEhX4/hqdefault.jpg According to the description, the episode explains epigenetic ageing clocks, tools that estimate biological age from chemical marks on DNA, and discusses their limits, including why measuring age in complex tissues such as blood can be misleading. https://www.youtube-nocookie.com/embed/LdP319eEhX4 471 2026-01-26T21:13:29.000Z 2026-10-23T02:46:02.511Z https://longevityharbor.com/de/watch/LdP319eEhX4 Videobeschreibung: epigenetische Uhren schätzen biologisches Alter an DNA-Markern https://i.ytimg.com/vi/LdP319eEhX4/hqdefault.jpg Laut Beschreibung erklärt die Episode epigenetische Altersuhren, Werkzeuge, die das biologische Alter anhand chemischer Markierungen auf der DNA schätzen, und behandelt ihre Grenzen, darunter warum Altersmessungen in komplexen Geweben wie Blut irreführend sein können. https://www.youtube-nocookie.com/embed/LdP319eEhX4 471 2026-01-26T21:13:29.000Z 2026-10-23T02:46:02.511Z https://longevityharbor.com/en/watch/Ljs2kPqms6Y Video description: five evening foods and brain health claims for people over 60 https://i.ytimg.com/vi/Ljs2kPqms6Y/hqdefault.jpg The description presents five evening foods and links sleep, nutrition and gut health to cognitive health in older adults; it states that no single food can prevent dementia. https://www.youtube-nocookie.com/embed/Ljs2kPqms6Y 1316 2026-10-01T07:00:28.000Z 2026-10-22T21:34:13.143Z https://longevityharbor.com/de/watch/Ljs2kPqms6Y Videobeschreibung: fünf Abend-Lebensmittel und Gehirngesundheit ab 60 https://i.ytimg.com/vi/Ljs2kPqms6Y/hqdefault.jpg Die Beschreibung stellt fünf Abend-Lebensmittel vor und verknüpft Schlaf, Ernährung und Darmgesundheit mit kognitiver Gesundheit im Alter; ein einzelnes Lebensmittel könne Demenz nicht verhindern, heißt es dort. https://www.youtube-nocookie.com/embed/Ljs2kPqms6Y 1316 2026-10-01T07:00:28.000Z 2026-10-22T21:34:13.143Z https://longevityharbor.com/en/watch/LkXRk2j7yNQ Muscle size vs. strength in very old adults: what the video description says https://i.ytimg.com/vi/LkXRk2j7yNQ/hqdefault.jpg According to the description, studies of adults in their 80s and 90s suggest muscle size may change less than expected, while strength and everyday function can improve markedly with resistance training. https://www.youtube-nocookie.com/embed/LkXRk2j7yNQ 1181 2026-10-07T14:44:46.000Z 2026-10-22T21:13:22.455Z https://longevityharbor.com/de/watch/LkXRk2j7yNQ Muskelgröße vs. Kraft bei sehr alten Erwachsenen: Was die Videobeschreibung sagt https://i.ytimg.com/vi/LkXRk2j7yNQ/hqdefault.jpg Laut Beschreibung legen Studien mit Erwachsenen in den 80ern und 90ern nahe, dass sich die Muskelgröße weniger stark ändert als erwartet, während Kraft und Alltagsfunktion durch Krafttraining deutlich zunehmen können. https://www.youtube-nocookie.com/embed/LkXRk2j7yNQ 1181 2026-10-07T14:44:46.000Z 2026-10-22T21:13:22.455Z https://longevityharbor.com/en/watch/LkxwdXrIOUk Video description: fasting and cellular repair mechanisms https://i.ytimg.com/vi/LkxwdXrIOUk/hqdefault.jpg The description says the video explains how fasting activates autophagy, mitophagy, AMPK, ketone production and growth hormone, and links this to cell repair, metabolic efficiency and reduced inflammation. These are creator claims; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/LkxwdXrIOUk 1282 2026-10-06T18:00:36.000Z 2026-10-22T21:16:02.791Z https://longevityharbor.com/de/watch/LkxwdXrIOUk Videobeschreibung: Fasten und zelluläre Reparaturmechanismen https://i.ytimg.com/vi/LkxwdXrIOUk/hqdefault.jpg Laut Beschreibung erklärt das Video, wie Fasten Autophagie, Mitophagie, AMPK, Ketonsynthese und Wachstumshormon aktiviert, und verknüpft dies mit Zellreparatur, Stoffwechseleffizienz und weniger Entzündung. Das sind Aussagen des Erstellers; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/LkxwdXrIOUk 1282 2026-10-06T18:00:36.000Z 2026-10-22T21:16:02.791Z https://longevityharbor.com/en/watch/Ln_ALGCWZkg Five Exercises After 70: What the Video Description Says https://i.ytimg.com/vi/Ln_ALGCWZkg/hqdefault.jpg The description presents five exercises for people over 70 — sit to stand, single leg stand, incline push up, farmer's carry and interval walking — and says the video covers safe execution, why each works and what research says about muscle loss, falls, grip strength and walking speed. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/Ln_ALGCWZkg 1146 2026-10-09T13:18:39.000Z 2026-10-22T20:48:33.845Z https://longevityharbor.com/de/watch/Ln_ALGCWZkg Fünf Übungen nach 70: Was die Videobeschreibung sagt https://i.ytimg.com/vi/Ln_ALGCWZkg/hqdefault.jpg Die Beschreibung stellt fünf Übungen für Menschen über 70 vor — Aufstehen vom Stuhl, Einbeinstand, Schräg-Liegestütz, Farmer's Carry und Intervallgehen — und sagt, das Video behandle sichere Ausführung, den Nutzen und was die Forschung zu Muskelverlust, Stürzen, Griffkraft und Gehgeschwindigkeit sagt. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/Ln_ALGCWZkg 1146 2026-10-09T13:18:39.000Z 2026-10-22T20:48:33.845Z https://longevityharbor.com/en/watch/LntAWVQMKqE Actionable Interventions in Human Aging: Insights from ARDD 2025 | Aging-US https://i.ytimg.com/vi/LntAWVQMKqE/hqdefault.jpg Aging-US #published this #meetingreport on April 6, 2026, in Volume 18, titled “Toward actionable interventions in human aging (12th ARDD meeting, 2025)" led by corresponding authors Aleksandr Dekan and Daniela Bakula from the Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark. @ardd3628 #aging #longevity #geroscience #biomarkers #meeting #openaccess #openscience #PaperSpotlight #peerreview #journal #publishing #meded DOI - https://doi.org/10.18632/aging.206368 Corresponding authors - Aleksandr Dekan - adekan@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk Abstract The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging. A central theme across sessions was the field’s gradual shift from descriptive, correlational studies to mechanistic understandings enabling the engineering of personalized therapeutic interventions aimed at extending human healthspan. Key discussions highlighted the convergence of multiple disciplines. Presentations detailed how fundamental biological insights are being integrated with artificial intelligence and machine learning platforms for accelerated target identification and drug development. Furthermore, the development and application of novel preclinical research models were presented as critical for improving the translational pipeline to human clinical trials. Scientific discourse has advanced from cataloging the established hallmarks of aging to identifying and modulating the specific molecular mechanisms that regulate them. This focus is predicated on the hypothesis that aging is not solely a result of stochastic damage accumulation but may be a tractable, modifiable, and potentially reversible biological process amenable to intervention. This report summarizes the principal research directions and conceptual frameworks presented at the conference. Sign up for free Altmetric alerts about this article - htt https://www.youtube-nocookie.com/embed/LntAWVQMKqE 119 2026-04-20T17:18:29.000Z 2026-10-22T19:04:38.835Z https://longevityharbor.com/de/watch/LntAWVQMKqE Actionable Interventions in Human Aging: Insights from ARDD 2025 | Aging-US https://i.ytimg.com/vi/LntAWVQMKqE/hqdefault.jpg Aging-US #published this #meetingreport on April 6, 2026, in Volume 18, titled “Toward actionable interventions in human aging (12th ARDD meeting, 2025)" led by corresponding authors Aleksandr Dekan and Daniela Bakula from the Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark. @ardd3628 #aging #longevity #geroscience #biomarkers #meeting #openaccess #openscience #PaperSpotlight #peerreview #journal #publishing #meded DOI - https://doi.org/10.18632/aging.206368 Corresponding authors - Aleksandr Dekan - adekan@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk Abstract The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging. A central theme across sessions was the field’s gradual shift from descriptive, correlational studies to mechanistic understandings enabling the engineering of personalized therapeutic interventions aimed at extending human healthspan. Key discussions highlighted the convergence of multiple disciplines. Presentations detailed how fundamental biological insights are being integrated with artificial intelligence and machine learning platforms for accelerated target identification and drug development. Furthermore, the development and application of novel preclinical research models were presented as critical for improving the translational pipeline to human clinical trials. Scientific discourse has advanced from cataloging the established hallmarks of aging to identifying and modulating the specific molecular mechanisms that regulate them. This focus is predicated on the hypothesis that aging is not solely a result of stochastic damage accumulation but may be a tractable, modifiable, and potentially reversible biological process amenable to intervention. This report summarizes the principal research directions and conceptual frameworks presented at the conference. Sign up for free Altmetric alerts about this article - htt https://www.youtube-nocookie.com/embed/LntAWVQMKqE 119 2026-04-20T17:18:29.000Z 2026-10-22T19:04:38.835Z https://longevityharbor.com/en/watch/LpYwcTFVnv8 Healthy, (Nutrient) Wealthy and Wise: Diet for Healthy Aging - Research on Aging https://i.ytimg.com/vi/LpYwcTFVnv8/hqdefault.jpg The Dietary Guidelines for Americans emphasize eating more foods from plants, such as vegetables and beans, whole grains, and nuts. Learn more about health benefits of choosing a diet heavy in fruits and vegetables from Katherine Richman, MD, Medical Director of Thornton Radiology and Clinical Professor of Radiology at the UC San Diego School of Medicine. [10/2015] [Show ID: 29305] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/LpYwcTFVnv8 3534 2015-10-01T21:54:29.000Z 2026-10-23T01:53:57.138Z https://longevityharbor.com/de/watch/LpYwcTFVnv8 Healthy, (Nutrient) Wealthy and Wise: Diet for Healthy Aging - Research on Aging https://i.ytimg.com/vi/LpYwcTFVnv8/hqdefault.jpg The Dietary Guidelines for Americans emphasize eating more foods from plants, such as vegetables and beans, whole grains, and nuts. Learn more about health benefits of choosing a diet heavy in fruits and vegetables from Katherine Richman, MD, Medical Director of Thornton Radiology and Clinical Professor of Radiology at the UC San Diego School of Medicine. [10/2015] [Show ID: 29305] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/LpYwcTFVnv8 3534 2015-10-01T21:54:29.000Z 2026-10-23T01:53:57.138Z https://longevityharbor.com/en/watch/LrQsJjMk2rU The Cell That Refused to Die: Cellular Senescence. #breakthroughjuniorchallenge https://i.ytimg.com/vi/LrQsJjMk2rU/hqdefault.jpg The Cell That Refused to Die: Cellular Senescence. #breakthroughjuniorchallenge https://www.youtube-nocookie.com/embed/LrQsJjMk2rU 90 2026-09-15T17:52:50.000Z 2026-10-22T19:43:47.841Z https://longevityharbor.com/de/watch/LrQsJjMk2rU The Cell That Refused to Die: Cellular Senescence. #breakthroughjuniorchallenge https://i.ytimg.com/vi/LrQsJjMk2rU/hqdefault.jpg The Cell That Refused to Die: Cellular Senescence. #breakthroughjuniorchallenge https://www.youtube-nocookie.com/embed/LrQsJjMk2rU 90 2026-09-15T17:52:50.000Z 2026-10-22T19:43:47.841Z https://longevityharbor.com/en/watch/LuQKXux8UlE Epigenetic Clocks Help to Find Anti-Aging Treatments | Steve Horvath | TEDxBerkeley https://i.ytimg.com/vi/LuQKXux8UlE/hqdefault.jpg Steve Horvath is a professor of human genetics and biostatistics at the University of California, Los Angeles. Horvath had a lifelong interest in solving an important problem in aging research: how do we measure aging? In 2011 Horvath and his collaborators at UCLA described the first age estimation method (epigenetic clock) for saliva based on chemical modifications of the DNA molecule known as DNA methylation. Two years later Horvath published an age estimator that applies to all tissues and cells of the human body. This discovery, known as the Horvath epigenetic clock, was unexpected because cells differ greatly in terms of their epigenetic patterns. Recently, he has studied treatments that slow or even reverse aging in humans. He and his colleagues have demonstrated that the epigenetic clock predicts lifespan and is related to centenarian status, obesity, HIV infection, early menopause, progeria, and many other age related conditions. Steve Horvath is a professor of human genetics and biostatistics at the University of California, Los Angeles. Horvath had a lifelong interest in solving an important problem in aging research: how do we measure aging? In 2011 Horvath and his collaborators at UCLA described the first age estimation method (epigenetic clock) for saliva based on chemical modifications of the DNA molecule known as DNA methylation. Two years later Horvath published an age estimator that applies to all tissues and cells of the human body. This discovery, known as the Horvath epigenetic clock, was unexpected because cells differ greatly in terms of their epigenetic patterns. Recently, he has studied treatments that slow or even reverse aging in humans. He and his colleagues have demonstrated that the epigenetic clock predicts lifespan and is related to centenarian status, obesity, HIV infection, early menopause, progeria, and many other age related conditions. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www. https://www.youtube-nocookie.com/embed/LuQKXux8UlE 873 2020-03-19T20:31:19.000Z 2026-10-22T17:43:35.136Z https://longevityharbor.com/de/watch/LuQKXux8UlE Epigenetic Clocks Help to Find Anti-Aging Treatments | Steve Horvath | TEDxBerkeley https://i.ytimg.com/vi/LuQKXux8UlE/hqdefault.jpg Steve Horvath is a professor of human genetics and biostatistics at the University of California, Los Angeles. Horvath had a lifelong interest in solving an important problem in aging research: how do we measure aging? In 2011 Horvath and his collaborators at UCLA described the first age estimation method (epigenetic clock) for saliva based on chemical modifications of the DNA molecule known as DNA methylation. Two years later Horvath published an age estimator that applies to all tissues and cells of the human body. This discovery, known as the Horvath epigenetic clock, was unexpected because cells differ greatly in terms of their epigenetic patterns. Recently, he has studied treatments that slow or even reverse aging in humans. He and his colleagues have demonstrated that the epigenetic clock predicts lifespan and is related to centenarian status, obesity, HIV infection, early menopause, progeria, and many other age related conditions. Steve Horvath is a professor of human genetics and biostatistics at the University of California, Los Angeles. Horvath had a lifelong interest in solving an important problem in aging research: how do we measure aging? In 2011 Horvath and his collaborators at UCLA described the first age estimation method (epigenetic clock) for saliva based on chemical modifications of the DNA molecule known as DNA methylation. Two years later Horvath published an age estimator that applies to all tissues and cells of the human body. This discovery, known as the Horvath epigenetic clock, was unexpected because cells differ greatly in terms of their epigenetic patterns. Recently, he has studied treatments that slow or even reverse aging in humans. He and his colleagues have demonstrated that the epigenetic clock predicts lifespan and is related to centenarian status, obesity, HIV infection, early menopause, progeria, and many other age related conditions. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www. https://www.youtube-nocookie.com/embed/LuQKXux8UlE 873 2020-03-19T20:31:19.000Z 2026-10-22T17:43:35.136Z https://longevityharbor.com/en/watch/M0FTJ6knI6E Nobody Wants to Live Long and Unhealthy | Diane Ty https://i.ytimg.com/vi/M0FTJ6knI6E/hqdefault.jpg Lifespan is the easy target. Healthspan is the real one. Diane Ty on geroscience, and on who gets access. Book Ian for your event → iankhan.com | booking@iankhan.com SUMMARY Diane Ty works on longevity and healthy ageing. She explains geroscience as the search for the common biological hallmarks of ageing, why delaying chronic disease matters more than extending years, and why access to personalised health planning is the harder problem. KEY FINDINGS • Geroscience targeting the common biological hallmarks of ageing • Delaying chronic disease rather than simply extending lifespan • Prevention and lifestyle management as the base layer • Tailoring a health plan to the individual to extend healthspan • Access to longevity technology as an unresolved challenge • Why the distinction between lifespan and healthspan changes policy • What augmented prevention could look like in practice GUEST Diane Ty, Longevity & Healthy Ageing FULL TRANSCRIPT iankhan.com/futurist/diane-ty-healthspan-geroscience Recorded at the Milken Institute Global Conference 2025 for The Futurist. ──────────────────── ABOUT IAN KHAN — AI & FINANCE KEYNOTE SPEAKER Most AI keynotes end with a better understanding. Mine end with a measured readiness score and a ninety-day plan. Your leadership team is assessed before the event, the room sees its own collective result live, and every attendee leaves with a ninety-day plan they helped build. Every year I interview more than 500 senior leaders on camera: scientists, operators, founders, regulators and investors. Those interviews become The Futurist and the annual State of Industry benchmarks. I don't deliver forecasts. I deliver evidence. Ranked a Top 25 Futurist worldwide, Global Gurus 2025 Thinkers50 Distinguished Award Finalist, 2025 USA Today and Publishers Weekly bestselling author, UNDISRUPTED Creator of the AI Readiness Score and the Future Readiness Score Three-time TEDx speaker · Keynotes in 60+ countries Featured on CNN, BBC, Bloomberg, Forbes and Fast Company BOOK IAN Keynotes, worksh https://www.youtube-nocookie.com/embed/M0FTJ6knI6E 538 2025-10-04T15:56:21.000Z 2026-10-22T19:04:37.480Z https://longevityharbor.com/de/watch/M0FTJ6knI6E Nobody Wants to Live Long and Unhealthy | Diane Ty https://i.ytimg.com/vi/M0FTJ6knI6E/hqdefault.jpg Lifespan is the easy target. Healthspan is the real one. Diane Ty on geroscience, and on who gets access. Book Ian for your event → iankhan.com | booking@iankhan.com SUMMARY Diane Ty works on longevity and healthy ageing. She explains geroscience as the search for the common biological hallmarks of ageing, why delaying chronic disease matters more than extending years, and why access to personalised health planning is the harder problem. KEY FINDINGS • Geroscience targeting the common biological hallmarks of ageing • Delaying chronic disease rather than simply extending lifespan • Prevention and lifestyle management as the base layer • Tailoring a health plan to the individual to extend healthspan • Access to longevity technology as an unresolved challenge • Why the distinction between lifespan and healthspan changes policy • What augmented prevention could look like in practice GUEST Diane Ty, Longevity & Healthy Ageing FULL TRANSCRIPT iankhan.com/futurist/diane-ty-healthspan-geroscience Recorded at the Milken Institute Global Conference 2025 for The Futurist. ──────────────────── ABOUT IAN KHAN — AI & FINANCE KEYNOTE SPEAKER Most AI keynotes end with a better understanding. Mine end with a measured readiness score and a ninety-day plan. Your leadership team is assessed before the event, the room sees its own collective result live, and every attendee leaves with a ninety-day plan they helped build. Every year I interview more than 500 senior leaders on camera: scientists, operators, founders, regulators and investors. Those interviews become The Futurist and the annual State of Industry benchmarks. I don't deliver forecasts. I deliver evidence. Ranked a Top 25 Futurist worldwide, Global Gurus 2025 Thinkers50 Distinguished Award Finalist, 2025 USA Today and Publishers Weekly bestselling author, UNDISRUPTED Creator of the AI Readiness Score and the Future Readiness Score Three-time TEDx speaker · Keynotes in 60+ countries Featured on CNN, BBC, Bloomberg, Forbes and Fast Company BOOK IAN Keynotes, worksh https://www.youtube-nocookie.com/embed/M0FTJ6knI6E 538 2025-10-04T15:56:21.000Z 2026-10-22T19:04:37.480Z https://longevityharbor.com/en/watch/M1GeILyuHac Video lists seven foods for healthy aging, stressing overall diet https://i.ytimg.com/vi/M1GeILyuHac/hqdefault.jpg The description lists seven foods or food groups said to fit a balanced diet for healthy aging, but states that no single food makes you long-lived; the whole diet and lifestyle matter. https://www.youtube-nocookie.com/embed/M1GeILyuHac 101 2026-09-16T19:55:23.000Z 2026-10-22T22:10:09.625Z https://longevityharbor.com/de/watch/M1GeILyuHac Video nennt sieben Lebensmittel für gesundes Altern und betont die Gesamternährung https://i.ytimg.com/vi/M1GeILyuHac/hqdefault.jpg Die Beschreibung nennt sieben Lebensmittel bzw. Lebensmittelgruppen, die in eine ausgewogene Ernährung für gesundes Altern passen sollen, betont aber: Kein einzelnes Lebensmittel macht langlebig; entscheidend sind Gesamternährung und Lebensstil. https://www.youtube-nocookie.com/embed/M1GeILyuHac 101 2026-09-16T19:55:23.000Z 2026-10-22T22:10:09.625Z https://longevityharbor.com/en/watch/M9Hr_PA3oM4 Genetics and muscle building: rare 'no-gainers' and training quality https://i.ytimg.com/vi/M9Hr_PA3oM4/hqdefault.jpg In the description, Prof. Dr. Ingo Froböse says genetic differences in muscle building exist, but true 'no-gainers' are extremely rare; often training, nutrition or the wrong loading form are the cause. https://www.youtube-nocookie.com/embed/M9Hr_PA3oM4 103 2026-01-06T15:45:06.000Z 2026-10-23T02:57:19.379Z https://longevityharbor.com/de/watch/M9Hr_PA3oM4 Genetik und Muskelaufbau: seltene „No-Gainer“ und Trainingsqualität https://i.ytimg.com/vi/M9Hr_PA3oM4/hqdefault.jpg In der Beschreibung sagt Prof. Dr. Ingo Froböse, genetische Unterschiede beim Muskelaufbau gebe es, echte „No-Gainer“ seien aber extrem selten; oft seien Training, Ernährung oder die falsche Belastungsform die Ursache. https://www.youtube-nocookie.com/embed/M9Hr_PA3oM4 103 2026-01-06T15:45:06.000Z 2026-10-23T02:57:19.379Z https://longevityharbor.com/en/watch/MErnfa9Dnb4 Lactic Acid Isn't The Enemy 🧪 #fitnessfacts #musclefatigue #science https://i.ytimg.com/vi/MErnfa9Dnb4/hqdefault.jpg It has long been thought that lactic acid is a harmful byproduct formed during exercise that causes muscle fatigue and soreness.However, close examination of shows that virtually no lactic acid appears in the body during exercise so it can’t cause fatigue. But research shows that the two products of lactic acid, lactate and acid, play separate roles during exercise and in the case of lactate are actually provide energy not reduce it. #lacticacid #lactate #musclefatigue #musclesoreness #fitnessfacts Reference: Cairns, S. P., & Lindinger, M. I. (2025). Lactic acidosis: implications for human exercise performance. European journal of applied physiology, 125(7), 1761–1795. DOI:10.1007/s00421-025-05750-0 About the Channel: Evidence-based fitness, nutrition, and health information from Dr. Jake Emmett, PhD, a retired Professor of Exercise Physiology with more than 30 years of teaching experience. Dr Jake Fitness Facts separates science from hype by debunking fitness myths, clarifying common misconceptions, and explaining what peer-reviewed research says about exercise, weight loss, fat loss, metabolism, muscle growth, strength training, cardio training, HIIT, Zone 2 cardio, protein, supplements, hydration, recovery, healthy aging, longevity, and human performance. Videos break down complex exercise science and physiology into clear, practical lessons that help viewers understand how the body works and how to apply research to real-world fitness and health decisions. No fad diets. No detox gimmicks. No influencer pseudoscience. Just science-based fitness education, myth-busting, and research-backed health information designed to help you train smarter, think critically, and make informed decisions about your health and fitness. Subscribe for evidence-based fitness facts and exercise science explained. https://www.youtube-nocookie.com/embed/MErnfa9Dnb4 117 2025-05-02T12:17:12.000Z 2026-10-22T20:11:50.312Z https://longevityharbor.com/de/watch/MErnfa9Dnb4 Lactic Acid Isn't The Enemy 🧪 #fitnessfacts #musclefatigue #science https://i.ytimg.com/vi/MErnfa9Dnb4/hqdefault.jpg It has long been thought that lactic acid is a harmful byproduct formed during exercise that causes muscle fatigue and soreness.However, close examination of shows that virtually no lactic acid appears in the body during exercise so it can’t cause fatigue. But research shows that the two products of lactic acid, lactate and acid, play separate roles during exercise and in the case of lactate are actually provide energy not reduce it. #lacticacid #lactate #musclefatigue #musclesoreness #fitnessfacts Reference: Cairns, S. P., & Lindinger, M. I. (2025). Lactic acidosis: implications for human exercise performance. European journal of applied physiology, 125(7), 1761–1795. DOI:10.1007/s00421-025-05750-0 About the Channel: Evidence-based fitness, nutrition, and health information from Dr. Jake Emmett, PhD, a retired Professor of Exercise Physiology with more than 30 years of teaching experience. Dr Jake Fitness Facts separates science from hype by debunking fitness myths, clarifying common misconceptions, and explaining what peer-reviewed research says about exercise, weight loss, fat loss, metabolism, muscle growth, strength training, cardio training, HIIT, Zone 2 cardio, protein, supplements, hydration, recovery, healthy aging, longevity, and human performance. Videos break down complex exercise science and physiology into clear, practical lessons that help viewers understand how the body works and how to apply research to real-world fitness and health decisions. No fad diets. No detox gimmicks. No influencer pseudoscience. Just science-based fitness education, myth-busting, and research-backed health information designed to help you train smarter, think critically, and make informed decisions about your health and fitness. Subscribe for evidence-based fitness facts and exercise science explained. https://www.youtube-nocookie.com/embed/MErnfa9Dnb4 117 2025-05-02T12:17:12.000Z 2026-10-22T20:11:50.312Z https://longevityharbor.com/en/watch/MFiNHaMJN6g Reverse Pre-Diabetes with a Fasting-Mimicking Diet, with Dr. Joseph Antoun https://i.ytimg.com/vi/MFiNHaMJN6g/hqdefault.jpg Reverse and prevent the damaging impacts of diabetes! Join CEO & Chairman of the Board of L-Nutra, Dr. Joseph Antoun, as he breaks down the causes and damaging impacts of diabetes. He shares decades worth of research and experience to give you actionable steps you can take to prevent and reverse the damage and enjoy longevity! Learn how to reverse pre-diabetes by listening to this episode today! For show notes, visit https://fivejourneys.com/podcasts/reverse-pre-diabetes-with-a-fasting-mimicking-diet/ Follow us on Instagram at hhttps://www.instagram.com/feelfreakingamazing/ Related episodes: Live Longer & Reverse Aging, with Dr. Kara Fitzgerald (https://fivejourneys.com/podcasts/live-longer-reverse-aging/) Age Into Your Best Self, with Dr. Deanna Minich (https://fivejourneys.com/podcasts/age-into-your-best-self/) Detox from Heavy Metals, with Wendy Myers (https://fivejourneys.com/podcasts/detox-from-heavy-metals/) Detox to Reverse Disease, with Dr. Joseph Pizzorno (https://fivejourneys.com/podcasts/detox-to-reverse-disease/) Lose Weight By Improving Your Leptin Sensitivity, with Dr. Bindiya Gandhi (https://fivejourneys.com/podcasts/lose-weight-by-improving-your-leptin-sensitivity/) Use the Right Supplements to Start Living Ageless, with Michele Drielick (https://fivejourneys.com/podcasts/use-the-right-supplements-to-start-living-ageless/) https://www.youtube-nocookie.com/embed/MFiNHaMJN6g 1195 2024-02-05T16:10:42.000Z 2026-10-22T19:32:32.189Z https://longevityharbor.com/de/watch/MFiNHaMJN6g Reverse Pre-Diabetes with a Fasting-Mimicking Diet, with Dr. Joseph Antoun https://i.ytimg.com/vi/MFiNHaMJN6g/hqdefault.jpg Reverse and prevent the damaging impacts of diabetes! Join CEO & Chairman of the Board of L-Nutra, Dr. Joseph Antoun, as he breaks down the causes and damaging impacts of diabetes. He shares decades worth of research and experience to give you actionable steps you can take to prevent and reverse the damage and enjoy longevity! Learn how to reverse pre-diabetes by listening to this episode today! For show notes, visit https://fivejourneys.com/podcasts/reverse-pre-diabetes-with-a-fasting-mimicking-diet/ Follow us on Instagram at hhttps://www.instagram.com/feelfreakingamazing/ Related episodes: Live Longer & Reverse Aging, with Dr. Kara Fitzgerald (https://fivejourneys.com/podcasts/live-longer-reverse-aging/) Age Into Your Best Self, with Dr. Deanna Minich (https://fivejourneys.com/podcasts/age-into-your-best-self/) Detox from Heavy Metals, with Wendy Myers (https://fivejourneys.com/podcasts/detox-from-heavy-metals/) Detox to Reverse Disease, with Dr. Joseph Pizzorno (https://fivejourneys.com/podcasts/detox-to-reverse-disease/) Lose Weight By Improving Your Leptin Sensitivity, with Dr. Bindiya Gandhi (https://fivejourneys.com/podcasts/lose-weight-by-improving-your-leptin-sensitivity/) Use the Right Supplements to Start Living Ageless, with Michele Drielick (https://fivejourneys.com/podcasts/use-the-right-supplements-to-start-living-ageless/) https://www.youtube-nocookie.com/embed/MFiNHaMJN6g 1195 2024-02-05T16:10:42.000Z 2026-10-22T19:32:32.189Z https://longevityharbor.com/en/watch/MJ8Iw4Kv3Kw LONGEVITY & PREVENTIVE MEDICINE: UPDATE OF THE LANDSCAPE https://i.ytimg.com/vi/MJ8Iw4Kv3Kw/hqdefault.jpg In this special episode you will have an opportunity to learn about the key factors to not only living longer but better and higher quality lives from a global expert and pioneer researcher in longevity medicine, Dr. David Barzilai. David provided an update of the landscape in this field as a keynote speaker at the 3rd annual Medical Affairs Innovation Olympics held in October. David is CEO and founder of Healthspan Coaching, LLC., and agingdoc.com, providing longevity medicine and lifestyle consulting. Dr. Barzilai is a Diplomate at the American Board of Lifestyle. He is board-certified in dermatology, with a PhD focused on evidence-based medicine, and also holds an MBA. In his keynote presentation, Dr. Barzilai critically addresses the gaps in treating only one disease at a time and provides alternative methods that target root, underlying causes of disease that can prevent multiple chronic diseases and lengthen the human Healthspan. David challenges the healthcare community and Medical Affairs function in pharma and biotech with a call to action to prioritize efforts to improve healthspan and transform medicine. 0:00 Timeline 0:09 Episode Highlight + Call to Action 1:30 Host Introduction of the Episode 4:17 Keynote Speaker's Presentation Overview 5:04 Dramatic Increase in Global Aging Population 6:10 Gray Tsunami Economic Impact - Rising Health Expenditures 7:07 Healthspan must accompany lifespan increase - Holy Grail of Longevity 7:41 Targeting the Bioscience of Aging: The Geroscience Hypothesis 8:21 12 Hallmarks of Aging 9:29 Problem with Current Approach of Targeting 1 Disease at a Time 10:26 Aging can be manipulated across different species Rapamycin increased lifespan even after being injected in middle aged humans 12:22 Growing Frontier in Longevity Biotech Number of biotech companies have grown from 20 to 50 since 2020 13:57 Lifestyle Medicine as Longevity Foundation 15:12 Global Strategy for Healthy Longevity Global Roadmap to Healthy Longevity National Academy of Medicine - https://www.youtube-nocookie.com/embed/MJ8Iw4Kv3Kw 1483 2024-11-30T02:43:40.000Z 2026-10-22T19:04:38.544Z https://longevityharbor.com/de/watch/MJ8Iw4Kv3Kw LONGEVITY & PREVENTIVE MEDICINE: UPDATE OF THE LANDSCAPE https://i.ytimg.com/vi/MJ8Iw4Kv3Kw/hqdefault.jpg In this special episode you will have an opportunity to learn about the key factors to not only living longer but better and higher quality lives from a global expert and pioneer researcher in longevity medicine, Dr. David Barzilai. David provided an update of the landscape in this field as a keynote speaker at the 3rd annual Medical Affairs Innovation Olympics held in October. David is CEO and founder of Healthspan Coaching, LLC., and agingdoc.com, providing longevity medicine and lifestyle consulting. Dr. Barzilai is a Diplomate at the American Board of Lifestyle. He is board-certified in dermatology, with a PhD focused on evidence-based medicine, and also holds an MBA. In his keynote presentation, Dr. Barzilai critically addresses the gaps in treating only one disease at a time and provides alternative methods that target root, underlying causes of disease that can prevent multiple chronic diseases and lengthen the human Healthspan. David challenges the healthcare community and Medical Affairs function in pharma and biotech with a call to action to prioritize efforts to improve healthspan and transform medicine. 0:00 Timeline 0:09 Episode Highlight + Call to Action 1:30 Host Introduction of the Episode 4:17 Keynote Speaker's Presentation Overview 5:04 Dramatic Increase in Global Aging Population 6:10 Gray Tsunami Economic Impact - Rising Health Expenditures 7:07 Healthspan must accompany lifespan increase - Holy Grail of Longevity 7:41 Targeting the Bioscience of Aging: The Geroscience Hypothesis 8:21 12 Hallmarks of Aging 9:29 Problem with Current Approach of Targeting 1 Disease at a Time 10:26 Aging can be manipulated across different species Rapamycin increased lifespan even after being injected in middle aged humans 12:22 Growing Frontier in Longevity Biotech Number of biotech companies have grown from 20 to 50 since 2020 13:57 Lifestyle Medicine as Longevity Foundation 15:12 Global Strategy for Healthy Longevity Global Roadmap to Healthy Longevity National Academy of Medicine - https://www.youtube-nocookie.com/embed/MJ8Iw4Kv3Kw 1483 2024-11-30T02:43:40.000Z 2026-10-22T19:04:38.544Z https://longevityharbor.com/en/watch/MJnGG7JZfGU Fasting vs Calorie Restriction - What’s More Effective? https://i.ytimg.com/vi/MJnGG7JZfGU/hqdefault.jpg Explore Fasting - https://www.vitalscend.com/fasting/ . Fasting and caloric restriction are quite similar in some regards, like promoting fat loss, ketosis, cognition, and metabolic health. Also, they can be a great strategy to increase energy in the long run, as our body becomes more efficient at burning fat for fuel. . But is all the buzz around fasting justified, and is it truly superior to traditional calorie restriction? Here, we'll provide a comprehensive review of the similarities and differences between these two dietary approaches, covering their definitions, timing, main focuses, benefits, challenges, and key differences. . 00:00 Intro 00:25 The Real Problem 01:42 Fasting vs. Caloric Restriction 02:00 Intermittent Fasting 03:30 Calorie Restriction 05:11 Health Benefits & Science 07:20 Key Differences 09:27 Takeaway . #fasting #intermittentfasting #caloricdeficit . Website: https://www.vitalscend.com https://www.tiktok.com/@simeon.cvejoski Pinterest: https://www.pinterest.com/vitalscend . Science / Research https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099935/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839325/ https://pubmed.ncbi.nlm.nih.gov/33531076/ https://pubmed.ncbi.nlm.nih.gov/31442403/ https://pubmed.ncbi.nlm.nih.gov/33652686/ . **Medical Disclaimer: The content on this Channel is for informational and entertaining purposes only. It is NOT intended to provide or replace professional medical advice, treatment, or diagnosis. Always consult with your physician, doctor, or another qualified healthcare professional regarding specific health questions or medical conditions. https://www.youtube-nocookie.com/embed/MJnGG7JZfGU 652 2023-10-27T14:26:44.000Z 2026-10-22T19:32:32.301Z https://longevityharbor.com/de/watch/MJnGG7JZfGU Fasting vs Calorie Restriction - What’s More Effective? https://i.ytimg.com/vi/MJnGG7JZfGU/hqdefault.jpg Explore Fasting - https://www.vitalscend.com/fasting/ . Fasting and caloric restriction are quite similar in some regards, like promoting fat loss, ketosis, cognition, and metabolic health. Also, they can be a great strategy to increase energy in the long run, as our body becomes more efficient at burning fat for fuel. . But is all the buzz around fasting justified, and is it truly superior to traditional calorie restriction? Here, we'll provide a comprehensive review of the similarities and differences between these two dietary approaches, covering their definitions, timing, main focuses, benefits, challenges, and key differences. . 00:00 Intro 00:25 The Real Problem 01:42 Fasting vs. Caloric Restriction 02:00 Intermittent Fasting 03:30 Calorie Restriction 05:11 Health Benefits & Science 07:20 Key Differences 09:27 Takeaway . #fasting #intermittentfasting #caloricdeficit . Website: https://www.vitalscend.com https://www.tiktok.com/@simeon.cvejoski Pinterest: https://www.pinterest.com/vitalscend . Science / Research https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099935/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839325/ https://pubmed.ncbi.nlm.nih.gov/33531076/ https://pubmed.ncbi.nlm.nih.gov/31442403/ https://pubmed.ncbi.nlm.nih.gov/33652686/ . **Medical Disclaimer: The content on this Channel is for informational and entertaining purposes only. It is NOT intended to provide or replace professional medical advice, treatment, or diagnosis. Always consult with your physician, doctor, or another qualified healthcare professional regarding specific health questions or medical conditions. https://www.youtube-nocookie.com/embed/MJnGG7JZfGU 652 2023-10-27T14:26:44.000Z 2026-10-22T19:32:32.301Z https://longevityharbor.com/en/watch/MN9ybpx-rn8 Video description on NMN, NAD and claimed anti-aging benefits https://i.ytimg.com/vi/MN9ybpx-rn8/hqdefault.jpg The description says the video explains what nicotinamide mononucleotide does in the body, how it supports NAD levels, and what clinical research reportedly shows about safety, anti-aging benefits and physical performance. No results are given in the description itself. https://www.youtube-nocookie.com/embed/MN9ybpx-rn8 372 2026-05-09T13:00:29.000Z 2026-10-23T01:06:56.520Z https://longevityharbor.com/de/watch/MN9ybpx-rn8 Videobeschreibung zu NMN, NAD und behaupteten Anti-Aging-Vorteilen https://i.ytimg.com/vi/MN9ybpx-rn8/hqdefault.jpg Laut Beschreibung erklärt das Video, was Nicotinamid-Mononukleotid im Körper tut, wie es NAD-Werte unterstützt und was klinische Forschung angeblich zu Sicherheit, Anti-Aging-Vorteilen und körperlicher Leistung zeigt. Die Beschreibung selbst nennt keine Ergebnisse. https://www.youtube-nocookie.com/embed/MN9ybpx-rn8 372 2026-05-09T13:00:29.000Z 2026-10-23T01:06:56.520Z https://longevityharbor.com/en/watch/MQcjFJGJ-jY 2 Millionen pro Jahr: Wer kauft sich ewige Jugend? https://i.ytimg.com/vi/MQcjFJGJ-jY/hqdefault.jpg 2 Millionen Dollar pro Jahr. So viel gibt Bryan Johnson aus, um sein biologisches Alter zu senken. Jeff Bezos investiert 3 Milliarden in Altos Labs, Sam Altman eine Milliarde in Retro Biosciences. Im Januar 2026 hat die FDA die erste klinische Studie zur Zellverjüngung durch epigenetische Reprogrammierung am Menschen genehmigt. Altern wird zum Markt — aber wer kann sich das leisten? Themen in diesem Video: – Die FDA-Zulassung: Life Biosciences und ER-100 als erste Gentherapie zur Zellverjüngung – Wie Yamanaka-Faktoren Zellen zurücksetzen können, ohne Tumor-Risiko – Das $85-Milliarden-Geschäft: Altos Labs, Retro Biosciences und das Longevity-Rennen – Bryan Johnson und die Rejuvenation Olympics: Biologisches Alter als Statussymbol – KI als Beschleuniger: Wie GPT-4b micro die Zellverjüngung 50× effizienter gemacht hat – Die Zwei-Klassen-Biologie: Warum die Reichsten jünger werden, während der Rest normal altert QUELLEN & KLARSTELLUNGEN: - Life Biosciences FDA IND Clearance (28.01.2026): lifebiosciences.com - Altos Labs Forschung: altoslabs.com/science - Retro Biosciences erste klinische Studie (RTR242): Longevity.Technology, 30.12.2025 - Anti-Aging Marktdaten: Gabelli Research, TowardsHealthcare 2026 - Bryan Johnson Blueprint Protokoll: protocol.bryanjohnson.com - OpenAI + Retro GPT-4b micro: OpenAI Blog, August 2025 - Epigenetische Uhr (Horvath Clock): Max-Planck-Institut für Biologie des Alterns Bryan Johnsons Aging-Score ist ein Einzelfall ohne Peer Review — er selbst bezeichnet ihn als „fun game". Die partielle epigenetische Reprogrammierung ist bei Life Biosciences in Phase 1 — noch keine bestätigte Wirksamkeit am Menschen. #BiologischesAlter #Longevity #Zellverjüngung #AlternStoppen #GeldGeneGigabytes 📌 KAPITEL: 0:00 — Altern stoppen: Die FDA genehmigt die erste Gentherapie zur Zellverjüngung 1:30 — Biologisches Alter messen: Was deine DNA wirklich über dich sagt 2:13 — Yamanaka-Faktoren erklärt: Wie man Zellen verjüngen kann (ohne Tumor-Risiko) 3:19 — Epigenetische Reprogrammierung am Menschen: Life Bi https://www.youtube-nocookie.com/embed/MQcjFJGJ-jY 654 2026-04-16T15:00:40.000Z 2026-10-22T19:43:50.789Z https://longevityharbor.com/de/watch/MQcjFJGJ-jY 2 Millionen pro Jahr: Wer kauft sich ewige Jugend? https://i.ytimg.com/vi/MQcjFJGJ-jY/hqdefault.jpg 2 Millionen Dollar pro Jahr. So viel gibt Bryan Johnson aus, um sein biologisches Alter zu senken. Jeff Bezos investiert 3 Milliarden in Altos Labs, Sam Altman eine Milliarde in Retro Biosciences. Im Januar 2026 hat die FDA die erste klinische Studie zur Zellverjüngung durch epigenetische Reprogrammierung am Menschen genehmigt. Altern wird zum Markt — aber wer kann sich das leisten? Themen in diesem Video: – Die FDA-Zulassung: Life Biosciences und ER-100 als erste Gentherapie zur Zellverjüngung – Wie Yamanaka-Faktoren Zellen zurücksetzen können, ohne Tumor-Risiko – Das $85-Milliarden-Geschäft: Altos Labs, Retro Biosciences und das Longevity-Rennen – Bryan Johnson und die Rejuvenation Olympics: Biologisches Alter als Statussymbol – KI als Beschleuniger: Wie GPT-4b micro die Zellverjüngung 50× effizienter gemacht hat – Die Zwei-Klassen-Biologie: Warum die Reichsten jünger werden, während der Rest normal altert QUELLEN & KLARSTELLUNGEN: - Life Biosciences FDA IND Clearance (28.01.2026): lifebiosciences.com - Altos Labs Forschung: altoslabs.com/science - Retro Biosciences erste klinische Studie (RTR242): Longevity.Technology, 30.12.2025 - Anti-Aging Marktdaten: Gabelli Research, TowardsHealthcare 2026 - Bryan Johnson Blueprint Protokoll: protocol.bryanjohnson.com - OpenAI + Retro GPT-4b micro: OpenAI Blog, August 2025 - Epigenetische Uhr (Horvath Clock): Max-Planck-Institut für Biologie des Alterns Bryan Johnsons Aging-Score ist ein Einzelfall ohne Peer Review — er selbst bezeichnet ihn als „fun game". Die partielle epigenetische Reprogrammierung ist bei Life Biosciences in Phase 1 — noch keine bestätigte Wirksamkeit am Menschen. #BiologischesAlter #Longevity #Zellverjüngung #AlternStoppen #GeldGeneGigabytes 📌 KAPITEL: 0:00 — Altern stoppen: Die FDA genehmigt die erste Gentherapie zur Zellverjüngung 1:30 — Biologisches Alter messen: Was deine DNA wirklich über dich sagt 2:13 — Yamanaka-Faktoren erklärt: Wie man Zellen verjüngen kann (ohne Tumor-Risiko) 3:19 — Epigenetische Reprogrammierung am Menschen: Life Bi https://www.youtube-nocookie.com/embed/MQcjFJGJ-jY 654 2026-04-16T15:00:40.000Z 2026-10-22T19:43:50.789Z https://longevityharbor.com/en/watch/MQs4s-pK_34 Surging Investment in Longevity & Geroscience - Michael Ringel at Longevity Summit Dublin 2024 https://i.ytimg.com/vi/MQs4s-pK_34/hqdefault.jpg Surging Investment in Longevity & Geroscience - Michael Ringel at Longevity Summit Dublin 2024 https://www.youtube-nocookie.com/embed/MQs4s-pK_34 2291 2024-07-06T10:57:44.000Z 2026-10-22T19:54:20.226Z https://longevityharbor.com/de/watch/MQs4s-pK_34 Surging Investment in Longevity & Geroscience - Michael Ringel at Longevity Summit Dublin 2024 https://i.ytimg.com/vi/MQs4s-pK_34/hqdefault.jpg Surging Investment in Longevity & Geroscience - Michael Ringel at Longevity Summit Dublin 2024 https://www.youtube-nocookie.com/embed/MQs4s-pK_34 2291 2024-07-06T10:57:44.000Z 2026-10-22T19:54:20.226Z https://longevityharbor.com/en/watch/MZ2vxZQHm-4 Rapamycin MTOR Longevity Detour https://i.ytimg.com/vi/MZ2vxZQHm-4/hqdefault.jpg The Rapamycin–mTOR Longevity Detour By Dr. Michael Wald, The Blood Detective Rapamycin is a drug originally used to prevent organ transplant rejection—but research shows it targets mTOR (mechanistic Target of Rapamycin), a cellular “switch” that regulates growth, repair, and aging. 🚦 Why mTOR Matters ON too often → Promotes cell growth, fat storage, and accelerates aging. OFF periodically → Activates autophagy, your body’s natural “cellular cleanup crew,” reducing inflammation and extending lifespan. 💊 Rapamycin’s Longevity Promise Mimics caloric restriction benefits without extreme dieting. Shown in animal studies to extend lifespan and healthspan. Potential to lower risk of age-related diseases (cancer, neurodegeneration, cardiovascular disease). ⚠️ The Detour – Risks & Caution Suppresses the immune system if overused. Can cause mouth ulcers, high blood sugar, and metabolic side effects. Still experimental for longevity in humans—research ongoing. ✅ Natural Alternatives to Support mTOR Balance Intermittent fasting or time-restricted eating. Plant-rich, anti-inflammatory diet (polyphenols help modulate mTOR). Exercise—a powerful natural regulator of mTOR activity. Stress reduction & quality sleep to improve cellular resilience. ⚡ Longevity is not about shortcuts—it’s about detours that must be navigated wisely. Rapamycin offers clues, but lifestyle remains the foundation. #TheBloodDetective #DrMichaelWald #Rapamycin #mTOR #Longevity #HealthyAging #CellularHealth #Biohacking #HealthTips #AntiAgingScience #HolisticHealth Follow Dr. Wald for science-backed strategies to outsmart disease. Dr Michael Wald https://DrMichaelWald.com New York Office 29 King St, Chappaqua, NY 10514 Virginia Office 4131 Croatan Rd, Richmond, VA 23235 Youtube https://www.youtube.com/@DrMichaelWald Linkedin https://www.linkedin.com/in/dr-michael-wald-blooddetective Facebook https://www.facebook.com/DoctorMichaelWald/ Instagram https://www.instagram.com/drmichaelwald/ X/Twitter https://x.com/DrMi https://www.youtube-nocookie.com/embed/MZ2vxZQHm-4 853 2025-08-27T13:45:08.000Z 2026-10-22T17:43:41.100Z https://longevityharbor.com/de/watch/MZ2vxZQHm-4 Rapamycin MTOR Longevity Detour https://i.ytimg.com/vi/MZ2vxZQHm-4/hqdefault.jpg The Rapamycin–mTOR Longevity Detour By Dr. Michael Wald, The Blood Detective Rapamycin is a drug originally used to prevent organ transplant rejection—but research shows it targets mTOR (mechanistic Target of Rapamycin), a cellular “switch” that regulates growth, repair, and aging. 🚦 Why mTOR Matters ON too often → Promotes cell growth, fat storage, and accelerates aging. OFF periodically → Activates autophagy, your body’s natural “cellular cleanup crew,” reducing inflammation and extending lifespan. 💊 Rapamycin’s Longevity Promise Mimics caloric restriction benefits without extreme dieting. Shown in animal studies to extend lifespan and healthspan. Potential to lower risk of age-related diseases (cancer, neurodegeneration, cardiovascular disease). ⚠️ The Detour – Risks & Caution Suppresses the immune system if overused. Can cause mouth ulcers, high blood sugar, and metabolic side effects. Still experimental for longevity in humans—research ongoing. ✅ Natural Alternatives to Support mTOR Balance Intermittent fasting or time-restricted eating. Plant-rich, anti-inflammatory diet (polyphenols help modulate mTOR). Exercise—a powerful natural regulator of mTOR activity. Stress reduction & quality sleep to improve cellular resilience. ⚡ Longevity is not about shortcuts—it’s about detours that must be navigated wisely. Rapamycin offers clues, but lifestyle remains the foundation. #TheBloodDetective #DrMichaelWald #Rapamycin #mTOR #Longevity #HealthyAging #CellularHealth #Biohacking #HealthTips #AntiAgingScience #HolisticHealth Follow Dr. Wald for science-backed strategies to outsmart disease. Dr Michael Wald https://DrMichaelWald.com New York Office 29 King St, Chappaqua, NY 10514 Virginia Office 4131 Croatan Rd, Richmond, VA 23235 Youtube https://www.youtube.com/@DrMichaelWald Linkedin https://www.linkedin.com/in/dr-michael-wald-blooddetective Facebook https://www.facebook.com/DoctorMichaelWald/ Instagram https://www.instagram.com/drmichaelwald/ X/Twitter https://x.com/DrMi https://www.youtube-nocookie.com/embed/MZ2vxZQHm-4 853 2025-08-27T13:45:08.000Z 2026-10-22T17:43:41.100Z https://longevityharbor.com/en/watch/Mdk-YcW7y8E „Der Longevity-Code: Das Epigenom - Deine…“ von Thomas Enzmann · Hörbuchauszug https://i.ytimg.com/vi/Mdk-YcW7y8E/hqdefault.jpg BEI GOOGLE PLAY BÜCHER KAUFEN ►► https://g.co/booksYT/AQAAAEAa2zCbOM Der Longevity-Code: Das Epigenom - Deine Software: Epigenetik verstehen & durch Lebensstil Medizin jünger werden. Der Longevity-Code · Buch 9 Verfasst von: Thomas Enzmann Vorgelesen von Alexander (AI) 0:00 Intro 0:03 2:28 5:03 Outro #thomasenzmann #derlongevitycode9 — GOOGLE PLAY BÜCHER Bei Google Play Bücher findest du immer wieder tollen Lesestoff. Google Play Bücher ist eine digitale Buchhandlung, die weltweit E-Books, Hörbücher, Comics und Mangas anbietet. Du findest dort Buchempfehlungen, die auf dich abgestimmt werden. iOS-App herunterladen: https://goo.gle/books-ios Android-App herunterladen: https://goo.gle/books-android — BUCHBESCHREIBUNG Hast du dich schon einmal gefragt, ob du deinen Genen hilflos ausgeliefert bist? Die Antwort lautet Nein. Deine DNA ist zwar der unveränderliche Bauplan, also die Hardware, aber das Epigenom ist die Software, die du selbst programmieren kannst. In dieser spannenden neunten Folge unserer Serie lernst du, wie biologische Selbstbestimmung wirklich funktioniert und wie du das Steuer deiner Gesundheit übernimmst. Wir zeigen dir, wie du durch gezielte Lebensstil Medizin dein biologisches Alter senken und den Alterungsprozess stoppen oder zumindest deutlich verlangsamen kannst. Es geht hierbei nicht darum, deine festen Erbanlagen zu verändern, sondern darum, wie Gene gesteuert werden. Du erfährst alles über die faszinierenden Mechanismen der DNA Methylierung und wie du Langlebigkeitsgene aktivieren kannst, während du gleichzeitig schädliche Entzündungsgene deaktivierst. Ein zentrales Thema dieser Ausgabe ist die sogenannte Horvath Uhr. Du lernst, wie man das biologische Alter testen kann und welche entscheidende Rolle die epigenetische Uhr für deine Vitalität spielt. Wir erklären dir verständlich und ohne Fachchinesisch komplexe Vorgänge wie die Histon Modifikation und warum eine effiziente DNA Reparatur der Schlüssel ist, um gesund altern zu können. Doch theoretisches Wissen allein reicht nich https://www.youtube-nocookie.com/embed/Mdk-YcW7y8E 325 2026-04-18T22:06:58.000Z 2026-10-22T18:54:03.291Z https://longevityharbor.com/de/watch/Mdk-YcW7y8E „Der Longevity-Code: Das Epigenom - Deine…“ von Thomas Enzmann · Hörbuchauszug https://i.ytimg.com/vi/Mdk-YcW7y8E/hqdefault.jpg BEI GOOGLE PLAY BÜCHER KAUFEN ►► https://g.co/booksYT/AQAAAEAa2zCbOM Der Longevity-Code: Das Epigenom - Deine Software: Epigenetik verstehen & durch Lebensstil Medizin jünger werden. Der Longevity-Code · Buch 9 Verfasst von: Thomas Enzmann Vorgelesen von Alexander (AI) 0:00 Intro 0:03 2:28 5:03 Outro #thomasenzmann #derlongevitycode9 — GOOGLE PLAY BÜCHER Bei Google Play Bücher findest du immer wieder tollen Lesestoff. Google Play Bücher ist eine digitale Buchhandlung, die weltweit E-Books, Hörbücher, Comics und Mangas anbietet. Du findest dort Buchempfehlungen, die auf dich abgestimmt werden. iOS-App herunterladen: https://goo.gle/books-ios Android-App herunterladen: https://goo.gle/books-android — BUCHBESCHREIBUNG Hast du dich schon einmal gefragt, ob du deinen Genen hilflos ausgeliefert bist? Die Antwort lautet Nein. Deine DNA ist zwar der unveränderliche Bauplan, also die Hardware, aber das Epigenom ist die Software, die du selbst programmieren kannst. In dieser spannenden neunten Folge unserer Serie lernst du, wie biologische Selbstbestimmung wirklich funktioniert und wie du das Steuer deiner Gesundheit übernimmst. Wir zeigen dir, wie du durch gezielte Lebensstil Medizin dein biologisches Alter senken und den Alterungsprozess stoppen oder zumindest deutlich verlangsamen kannst. Es geht hierbei nicht darum, deine festen Erbanlagen zu verändern, sondern darum, wie Gene gesteuert werden. Du erfährst alles über die faszinierenden Mechanismen der DNA Methylierung und wie du Langlebigkeitsgene aktivieren kannst, während du gleichzeitig schädliche Entzündungsgene deaktivierst. Ein zentrales Thema dieser Ausgabe ist die sogenannte Horvath Uhr. Du lernst, wie man das biologische Alter testen kann und welche entscheidende Rolle die epigenetische Uhr für deine Vitalität spielt. Wir erklären dir verständlich und ohne Fachchinesisch komplexe Vorgänge wie die Histon Modifikation und warum eine effiziente DNA Reparatur der Schlüssel ist, um gesund altern zu können. Doch theoretisches Wissen allein reicht nich https://www.youtube-nocookie.com/embed/Mdk-YcW7y8E 325 2026-04-18T22:06:58.000Z 2026-10-22T18:54:03.291Z https://longevityharbor.com/en/watch/MiOZ1GPaCt8 Video description on senolytics and senescent 'zombie cells' https://i.ytimg.com/vi/MiOZ1GPaCt8/hqdefault.jpg The description says senescent cells stop dividing, resist dying and release chemicals linked to inflammation and aging, and that senolytics may clear them; no results are reported. https://www.youtube-nocookie.com/embed/MiOZ1GPaCt8 591 2026-09-20T07:00:39.000Z 2026-10-22T22:04:15.518Z https://longevityharbor.com/de/watch/MiOZ1GPaCt8 Videobeschreibung zu Senolytika und seneszenten „Zombie-Zellen“ https://i.ytimg.com/vi/MiOZ1GPaCt8/hqdefault.jpg Laut Beschreibung hören seneszente Zellen auf zu teilen, sterben nicht und setzen Stoffe frei, die mit Entzündung und Altern verbunden werden; Senolytika könnten sie beseitigen. Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/MiOZ1GPaCt8 591 2026-09-20T07:00:39.000Z 2026-10-22T22:04:15.518Z https://longevityharbor.com/en/watch/MkQEiXFGiEc Video description: Zone 2 training and metabolic health in aging https://i.ytimg.com/vi/MkQEiXFGiEc/hqdefault.jpg The description says many researchers see Zone 2, a low-intensity steady aerobic effort, as important for metabolic health with age, and it promises a look at mitochondrial function, lactate clearance and fuel switching. https://www.youtube-nocookie.com/embed/MkQEiXFGiEc 708 2026-09-26T21:12:43.000Z 2026-10-22T21:44:22.634Z https://longevityharbor.com/de/watch/MkQEiXFGiEc Videobeschreibung: Zone-2-Training und Stoffwechselgesundheit im Altern https://i.ytimg.com/vi/MkQEiXFGiEc/hqdefault.jpg Laut Beschreibung sehen viele Forschende Zone 2, eine niedrigintensive gleichmäßige aerobe Belastung, als wichtig für die Stoffwechselgesundheit im Alter; versprochen wird ein Blick auf Mitochondrienfunktion, Laktatabbau und den Wechsel zwischen Brennstoffen. https://www.youtube-nocookie.com/embed/MkQEiXFGiEc 708 2026-09-26T21:12:43.000Z 2026-10-22T21:44:22.634Z https://longevityharbor.com/en/watch/MksivNbHRPI What strength training twice weekly for 30 days may do to muscles from age 50 https://i.ytimg.com/vi/MksivNbHRPI/hqdefault.jpg The description says strength training twice weekly for four weeks can start strength gains mainly through better nerve-muscle coordination; visible muscle changes usually need more time. https://www.youtube-nocookie.com/embed/MksivNbHRPI 1832 2026-09-10T11:30:18.000Z 2026-10-22T22:18:39.551Z https://longevityharbor.com/de/watch/MksivNbHRPI Was Krafttraining zweimal pro Woche über 30 Tage ab 50 mit Muskeln tun kann https://i.ytimg.com/vi/MksivNbHRPI/hqdefault.jpg Laut Beschreibung kann Krafttraining zweimal pro Woche über vier Wochen Kraftzuwächse vor allem über bessere Zusammenarbeit von Nerven und Muskeln starten; sichtbare Muskelveränderungen brauchen meist mehr Zeit. https://www.youtube-nocookie.com/embed/MksivNbHRPI 1832 2026-09-10T11:30:18.000Z 2026-10-22T22:18:39.551Z https://longevityharbor.com/en/watch/MkuWE4QNuo0 The CRONA Study: How Calorie Restriction Affects Aging and Health https://i.ytimg.com/vi/MkuWE4QNuo0/hqdefault.jpg http://www.ucsf.edu/news/2011/04/9740/extreme-dieting-does-it-lead-longer-lives UCSF researcher Janet Tomiyama and long-time calorie restrictor Tadd Ottman discuss a milestone study on health and aging. In some species—for example fish, mice, worms and yeast—animals experience much longer life spans by simply consuming less calories. The Calorie Restriction With Optimal Nutrition and Aging (CRONA) study at UCSF hopes to determine if the same process can be applied to humans. The study is being done in collaboration with Elizabeth Blackburn, who won a Nobel prize in 2010 for her discovery of telomeres, and Cynthia Kenyon, who is considered a pioneer of longevity research. https://www.youtube-nocookie.com/embed/MkuWE4QNuo0 151 2011-04-19T01:00:55.000Z 2026-10-22T17:43:38.396Z https://longevityharbor.com/de/watch/MkuWE4QNuo0 The CRONA Study: How Calorie Restriction Affects Aging and Health https://i.ytimg.com/vi/MkuWE4QNuo0/hqdefault.jpg http://www.ucsf.edu/news/2011/04/9740/extreme-dieting-does-it-lead-longer-lives UCSF researcher Janet Tomiyama and long-time calorie restrictor Tadd Ottman discuss a milestone study on health and aging. In some species—for example fish, mice, worms and yeast—animals experience much longer life spans by simply consuming less calories. The Calorie Restriction With Optimal Nutrition and Aging (CRONA) study at UCSF hopes to determine if the same process can be applied to humans. The study is being done in collaboration with Elizabeth Blackburn, who won a Nobel prize in 2010 for her discovery of telomeres, and Cynthia Kenyon, who is considered a pioneer of longevity research. https://www.youtube-nocookie.com/embed/MkuWE4QNuo0 151 2011-04-19T01:00:55.000Z 2026-10-22T17:43:38.396Z https://longevityharbor.com/en/watch/Mr3Rq2yewfQ Why Older Adults Wake at 3 A.M.: A Video Explainer on Age-Related Sleep Changes https://i.ytimg.com/vi/Mr3Rq2yewfQ/hqdefault.jpg This video description says it covers what changes in sleep with age, from sleep cycles and the body clock to the ageing eye, and what research says helps. It offers general information, not medical advice, and lists its sources. https://www.youtube-nocookie.com/embed/Mr3Rq2yewfQ 454 2026-10-18T19:00:13.000Z 2026-10-22T19:50:45.746Z https://longevityharbor.com/de/watch/Mr3Rq2yewfQ Warum ältere Menschen um 3 Uhr nachts aufwachen: Ein Video-Erklärer zu altersassoziierten Schlafverä https://i.ytimg.com/vi/Mr3Rq2yewfQ/hqdefault.jpg Diese Videobeschreibung gibt an, zu behandeln, was sich beim Schlaf mit dem Alter verändert – von Schlafzyklen und innerer Uhr bis zum alternden Auge – und was laut Forschung hilft. Sie ist allgemeine Information, kein medizinischer Rat, und nennt ihre Quellen. https://www.youtube-nocookie.com/embed/Mr3Rq2yewfQ 454 2026-10-18T19:00:13.000Z 2026-10-22T19:50:45.746Z https://longevityharbor.com/en/watch/MyAoAvTwOoo The Dark Side of Rapamycin: What You Need to Know Before Taking It https://i.ytimg.com/vi/MyAoAvTwOoo/hqdefault.jpg Rapamycin anti-aging research: a transplant drug that may slow biological ageing is already being prescribed by telehealth companies — but does the human evidence justify that? Dr. Armstrong and the MedHeads team break down exactly where the science stands in 2025. 🔬 WHAT RAPAMYCIN ACTUALLY DOES INSIDE YOUR CELLS Rapamycin blocks a cellular pathway called mTOR — essentially a nutrient sensor that keeps your cells in constant growth mode. Inhibiting mTOR forces cells into maintenance mode, triggering autophagy: a housekeeping process that clears out damaged proteins and recycled components. On paper, that mechanism should slow biological ageing. In middle-aged mice, it really does — delaying cancer, neurodegeneration, and other age-related diseases. 📊 THE MOST EXCITING MOUSE DATA (AND WHY IT DOESN'T CLINCH IT) A May 2025 study published in Nature Aging combined rapamycin with trimetinib and found around 30% longer lifespans in animals, less inflammation across multiple organs, delayed cancer onset, and preserved cognitive function. Genuinely striking results — in mice. Translating animal research to humans fails more often than it succeeds, and no randomised controlled trial has yet shown that healthy people on rapamycin live longer. 🧪 WHAT THE HUMAN TRIALS ACTUALLY FOUND The PEARL trial (April 2025) enrolled healthy adults aged 50–85, randomised to 5 or 10 mg of rapamycin weekly or a placebo for 48 weeks. Primary endpoint: no significant effect. There were secondary signals — modest muscle gains in women on the higher dose and some immune marker changes — but PEARL did not prove rapamycin slows human ageing. Separately, the Vibrant pilot study found rapamycin may slow ovarian ageing by around 20%, a real biological effect — but one pilot study is a starting point, not a conclusion. ⚠️ DOSE, SIDE EFFECTS, AND THE SAFETY GAP Transplant patients take 2–5 mg daily for continuous immunosuppression. Longevity users typically try 5–7 mg once a week, an intermittent approach thought to produce some mTOR inhibition https://www.youtube-nocookie.com/embed/MyAoAvTwOoo 292 2026-06-21T14:00:23.000Z 2026-10-22T17:43:41.069Z https://longevityharbor.com/de/watch/MyAoAvTwOoo The Dark Side of Rapamycin: What You Need to Know Before Taking It https://i.ytimg.com/vi/MyAoAvTwOoo/hqdefault.jpg Rapamycin anti-aging research: a transplant drug that may slow biological ageing is already being prescribed by telehealth companies — but does the human evidence justify that? Dr. Armstrong and the MedHeads team break down exactly where the science stands in 2025. 🔬 WHAT RAPAMYCIN ACTUALLY DOES INSIDE YOUR CELLS Rapamycin blocks a cellular pathway called mTOR — essentially a nutrient sensor that keeps your cells in constant growth mode. Inhibiting mTOR forces cells into maintenance mode, triggering autophagy: a housekeeping process that clears out damaged proteins and recycled components. On paper, that mechanism should slow biological ageing. In middle-aged mice, it really does — delaying cancer, neurodegeneration, and other age-related diseases. 📊 THE MOST EXCITING MOUSE DATA (AND WHY IT DOESN'T CLINCH IT) A May 2025 study published in Nature Aging combined rapamycin with trimetinib and found around 30% longer lifespans in animals, less inflammation across multiple organs, delayed cancer onset, and preserved cognitive function. Genuinely striking results — in mice. Translating animal research to humans fails more often than it succeeds, and no randomised controlled trial has yet shown that healthy people on rapamycin live longer. 🧪 WHAT THE HUMAN TRIALS ACTUALLY FOUND The PEARL trial (April 2025) enrolled healthy adults aged 50–85, randomised to 5 or 10 mg of rapamycin weekly or a placebo for 48 weeks. Primary endpoint: no significant effect. There were secondary signals — modest muscle gains in women on the higher dose and some immune marker changes — but PEARL did not prove rapamycin slows human ageing. Separately, the Vibrant pilot study found rapamycin may slow ovarian ageing by around 20%, a real biological effect — but one pilot study is a starting point, not a conclusion. ⚠️ DOSE, SIDE EFFECTS, AND THE SAFETY GAP Transplant patients take 2–5 mg daily for continuous immunosuppression. Longevity users typically try 5–7 mg once a week, an intermittent approach thought to produce some mTOR inhibition https://www.youtube-nocookie.com/embed/MyAoAvTwOoo 292 2026-06-21T14:00:23.000Z 2026-10-22T17:43:41.069Z https://longevityharbor.com/en/watch/MyuyLyZnilg What If Fasting Is The KEY To LONGEVITY? Dr. Valter Longo & Dr. Steven Gundry https://i.ytimg.com/vi/MyuyLyZnilg/hqdefault.jpg Fasting, longevity, and disease prevention—how can fasting transform your health? Dr. Valter Longo joins Dr. Steven Gundry to reveal the science behind fasting, aging, and optimal health. Dr. Longo, creator of the fasting-mimicking diet, shares how strategic fasting can reduce biological age, boost longevity, and improve key health markers like metabolism, immune function, and energy levels. His latest book, Fasting Cancer, explores how fasting and nutrition can revolutionize health and wellness. Dr. Longo's new book is available now - https://www.amazon.com/Fasting-Cancer-Nutritechnology-Revolution-Prevention/dp/059354532X In this episode, Dr. Gundry and Dr. Longo break down: ✅ The biggest dietary mistakes doctors make when advising patients ✅ How fasting doesn’t always mean going without food (and how to do it right) ✅ The fasting technique that enhances cellular repair and longevity ✅ The truth about water fasting—does it help or harm your body? ✅ Can GLP-1 weight loss drugs fix the obesity crisis? ✅ Why the Blue Zones diet may not work for everyone ✅ Animal protein and aging—should you eat more or less? ✅ Simple diet and fasting strategies to help you live longer and prevent disease This episode is packed with actionable longevity tips—don’t miss it! Pre-order Dr. Gundry's new book, The Gut-Brain Paradox now! - http://rebrand.ly/gut-brain-paradox-book To be one of the first to learn more life-changing tips and tricks, sign up for my newsletter here: https://drgundry.m-pages.com/J14aDI/gundry-newsletter 00:00 - The biggest diet mistakes doctors make for long-term health 02:38 - Fasting without starving—how to do it right 05:57 - Water fasting: Helpful or harmful? 06:33 - The fasting technique that supports longevity and cellular repair 22:58 - Are GLP-1 weight loss drugs the solution to obesity? 29:15 - The truth about the Blue Zones diet—who should follow it? 30:18 - What you can do TODAY to prevent disease and live longer 33:21 - Should you increase animal protein as you age? 🔔 Subscribe for expert i https://www.youtube-nocookie.com/embed/MyuyLyZnilg 2411 2025-03-21T17:45:28.000Z 2026-10-22T19:32:31.955Z https://longevityharbor.com/de/watch/MyuyLyZnilg What If Fasting Is The KEY To LONGEVITY? Dr. Valter Longo & Dr. Steven Gundry https://i.ytimg.com/vi/MyuyLyZnilg/hqdefault.jpg Fasting, longevity, and disease prevention—how can fasting transform your health? Dr. Valter Longo joins Dr. Steven Gundry to reveal the science behind fasting, aging, and optimal health. Dr. Longo, creator of the fasting-mimicking diet, shares how strategic fasting can reduce biological age, boost longevity, and improve key health markers like metabolism, immune function, and energy levels. His latest book, Fasting Cancer, explores how fasting and nutrition can revolutionize health and wellness. Dr. Longo's new book is available now - https://www.amazon.com/Fasting-Cancer-Nutritechnology-Revolution-Prevention/dp/059354532X In this episode, Dr. Gundry and Dr. Longo break down: ✅ The biggest dietary mistakes doctors make when advising patients ✅ How fasting doesn’t always mean going without food (and how to do it right) ✅ The fasting technique that enhances cellular repair and longevity ✅ The truth about water fasting—does it help or harm your body? ✅ Can GLP-1 weight loss drugs fix the obesity crisis? ✅ Why the Blue Zones diet may not work for everyone ✅ Animal protein and aging—should you eat more or less? ✅ Simple diet and fasting strategies to help you live longer and prevent disease This episode is packed with actionable longevity tips—don’t miss it! Pre-order Dr. Gundry's new book, The Gut-Brain Paradox now! - http://rebrand.ly/gut-brain-paradox-book To be one of the first to learn more life-changing tips and tricks, sign up for my newsletter here: https://drgundry.m-pages.com/J14aDI/gundry-newsletter 00:00 - The biggest diet mistakes doctors make for long-term health 02:38 - Fasting without starving—how to do it right 05:57 - Water fasting: Helpful or harmful? 06:33 - The fasting technique that supports longevity and cellular repair 22:58 - Are GLP-1 weight loss drugs the solution to obesity? 29:15 - The truth about the Blue Zones diet—who should follow it? 30:18 - What you can do TODAY to prevent disease and live longer 33:21 - Should you increase animal protein as you age? 🔔 Subscribe for expert i https://www.youtube-nocookie.com/embed/MyuyLyZnilg 2411 2025-03-21T17:45:28.000Z 2026-10-22T19:32:31.955Z https://longevityharbor.com/en/watch/MznKuFkJ5Ew PANEL: Geroscience Interventions that Target Frailty https://i.ytimg.com/vi/MznKuFkJ5Ew/hqdefault.jpg PANEL: Geroscience Interventions that Target Frailty Sara Espinoza, MD, MsC, Center for Geroscience Medicine, Cedars Sinai Medical Center, USA Isabel Rodriguez, MD, PhD, Universidad Complutense de Madrid, Spain Gustavo Duque, MD, PhD, McGill University, Canada https://www.youtube-nocookie.com/embed/MznKuFkJ5Ew 3296 2024-07-13T17:38:56.000Z 2026-10-22T19:32:34.526Z https://longevityharbor.com/de/watch/MznKuFkJ5Ew PANEL: Geroscience Interventions that Target Frailty https://i.ytimg.com/vi/MznKuFkJ5Ew/hqdefault.jpg PANEL: Geroscience Interventions that Target Frailty Sara Espinoza, MD, MsC, Center for Geroscience Medicine, Cedars Sinai Medical Center, USA Isabel Rodriguez, MD, PhD, Universidad Complutense de Madrid, Spain Gustavo Duque, MD, PhD, McGill University, Canada https://www.youtube-nocookie.com/embed/MznKuFkJ5Ew 3296 2024-07-13T17:38:56.000Z 2026-10-22T19:32:34.526Z https://longevityharbor.com/en/watch/N01e6Q5IxvE Video description: inflammation, aging and low-dose rapamycin as described https://i.ytimg.com/vi/N01e6Q5IxvE/hqdefault.jpg The description says chronic low-grade inflammation rises with age and reduces the body's ability to adapt, and that keeping inflammatory responses and the mTOR pathway in a healthy dynamic range matters for long-term health; low-dose rapamycin is mentioned as a possible method. https://www.youtube-nocookie.com/embed/N01e6Q5IxvE 161 2026-09-25T07:01:23.000Z 2026-10-22T21:51:10.457Z https://longevityharbor.com/de/watch/N01e6Q5IxvE Videobeschreibung: Entzündung, Altern und niedrig dosiertes Rapamycin laut Beschreibung https://i.ytimg.com/vi/N01e6Q5IxvE/hqdefault.jpg Laut Beschreibung nimmt chronisch niedriggradige Entzündung mit dem Alter zu und verringert die Anpassungsfähigkeit des Körpers; eine gesunde dynamische Bandbreite der Entzündungsantworten und des mTOR-Signalwegs sei für langfristige Gesundheit wichtig. Niedrig dosiertes Rapamycin wird als mögliche Methode genannt. https://www.youtube-nocookie.com/embed/N01e6Q5IxvE 161 2026-09-25T07:01:23.000Z 2026-10-22T21:51:10.457Z https://longevityharbor.com/en/watch/N4vlwuz1cJA Video description: strength training, muscle and brain ageing claims https://i.ytimg.com/vi/N4vlwuz1cJA/hqdefault.jpg The description says Dr Alex Wibberley explains how muscle relates to brain ageing and why resistance training is presented as a way to preserve thinking speed, memory and cognitive resilience. It lists proposed mechanisms and long-term studies on strength and dementia risk, but gives no results. https://www.youtube-nocookie.com/embed/N4vlwuz1cJA 1470 2026-01-18T14:00:29.000Z 2026-10-23T02:49:19.132Z https://longevityharbor.com/de/watch/N4vlwuz1cJA Videobeschreibung: Krafttraining, Muskel und Gehirnalterung https://i.ytimg.com/vi/N4vlwuz1cJA/hqdefault.jpg Laut Beschreibung erklärt Dr. Alex Wibberley, wie Muskel und Gehirnalterung zusammenhängen und warum Krafttraining als Weg gilt, Denkgeschwindigkeit, Gedächtnis und kognitive Widerstandskraft zu erhalten. Sie nennt vorgeschlagene Mechanismen und Langzeitstudien zu Kraft und Demenzrisiko, aber keine Ergebnisse. https://www.youtube-nocookie.com/embed/N4vlwuz1cJA 1470 2026-01-18T14:00:29.000Z 2026-10-23T02:49:19.132Z https://longevityharbor.com/en/watch/NDhoIXPdnQo Video description: foods for healthy aging, protein, fiber and skin https://i.ytimg.com/vi/NDhoIXPdnQo/hqdefault.jpg The description says the video covers foods for healthy aging, protein for muscle, fiber-rich foods and nutrition for skin, and states that no food can stop aging. https://www.youtube-nocookie.com/embed/NDhoIXPdnQo 501 2026-10-17T06:11:26.000Z 2026-10-22T21:09:50.566Z https://longevityharbor.com/de/watch/NDhoIXPdnQo Videobeschreibung: Lebensmittel für gesundes Altern, Protein, Ballaststoffe und Haut https://i.ytimg.com/vi/NDhoIXPdnQo/hqdefault.jpg Laut Beschreibung behandelt das Video Lebensmittel für gesundes Altern, Protein für die Muskulatur, ballaststoffreiche Lebensmittel und Ernährung für die Haut; kein Lebensmittel könne das Altern stoppen. https://www.youtube-nocookie.com/embed/NDhoIXPdnQo 501 2026-10-17T06:11:26.000Z 2026-10-22T21:09:50.566Z https://longevityharbor.com/en/watch/NKWbYkrO3sQ Podcast: Rapamycin, genes and mouse lifespan research on slowing aging https://i.ytimg.com/vi/NKWbYkrO3sQ/hqdefault.jpg In this podcast description, Dr. Rich Miller discusses mouse studies of genetic mutants, calorie restriction and drugs such as rapamycin, plus the difficulty of translating these results to humans. https://www.youtube-nocookie.com/embed/NKWbYkrO3sQ 2224 2026-09-22T11:30:24.000Z 2026-10-22T21:58:11.738Z https://longevityharbor.com/de/watch/NKWbYkrO3sQ Podcast: Rapamycin, Gene und Maus-Lebensspanne in der Alternsforschung https://i.ytimg.com/vi/NKWbYkrO3sQ/hqdefault.jpg In dieser Podcast-Beschreibung spricht Dr. Rich Miller über Mausstudien mit genetischen Mutanten, Kalorienrestriktion und Wirkstoffen wie Rapamycin sowie über die Schwierigkeit, diese Ergebnisse auf Menschen zu übertragen. https://www.youtube-nocookie.com/embed/NKWbYkrO3sQ 2224 2026-09-22T11:30:24.000Z 2026-10-22T21:58:11.738Z https://longevityharbor.com/en/watch/NNqmRXL-y24 Video description: proposed 14-node aging network and precision geromedicine https://i.ytimg.com/vi/NNqmRXL-y24/hqdefault.jpg The description says geroscience now frames aging as a regulated biological process, with the Hallmarks of Aging growing from nine in 2013 to as many as fourteen by 2025 and organized into a three-part hierarchy toward precision geromedicine. https://www.youtube-nocookie.com/embed/NNqmRXL-y24 578 2026-03-21T02:57:35.000Z 2026-10-23T01:59:25.906Z https://longevityharbor.com/de/watch/NNqmRXL-y24 Videobeschreibung: vorgeschlagenes 14-Knoten-Alterungsnetz und Präzisions-Geromedizin https://i.ytimg.com/vi/NNqmRXL-y24/hqdefault.jpg Laut Beschreibung betrachtet die Gerowissenschaft das Altern heute als regulierten biologischen Prozess; die Hallmarks of Aging wuchsen von neun im Jahr 2013 auf bis zu vierzehn bis 2025 und sind in einer dreiteiligen Hierarchie auf Präzisions-Geromedizin ausgerichtet. https://www.youtube-nocookie.com/embed/NNqmRXL-y24 578 2026-03-21T02:57:35.000Z 2026-10-23T01:59:25.906Z https://longevityharbor.com/en/watch/NS0LAVyG7y0 Here’s how to take NMN the right way to get best results https://i.ytimg.com/vi/NS0LAVyG7y0/hqdefault.jpg Here’s how to take NMN the right way to get best results. #antiaging #nmn #tiktokshopjumpstartsale #newyearnewme #glowup https://www.youtube-nocookie.com/embed/NS0LAVyG7y0 135 2026-09-21T19:09:07.000Z 2026-10-22T20:11:47.052Z https://longevityharbor.com/de/watch/NS0LAVyG7y0 Here’s how to take NMN the right way to get best results https://i.ytimg.com/vi/NS0LAVyG7y0/hqdefault.jpg Here’s how to take NMN the right way to get best results. #antiaging #nmn #tiktokshopjumpstartsale #newyearnewme #glowup https://www.youtube-nocookie.com/embed/NS0LAVyG7y0 135 2026-09-21T19:09:07.000Z 2026-10-22T20:11:47.052Z https://longevityharbor.com/en/watch/NU98SXBCjz4 333 ‒ Longevity roundtable—the science of aging, geroprotective molecules, & lifestyle interventions https://i.ytimg.com/vi/NU98SXBCjz4/hqdefault.jpg In this special episode of The Drive, Peter introduces a brand-new roundtable format. Joined by three renowned experts in longevity science—Steven Austad, Richard Miller, and Matt Kaeberlein—the group explores the rapidly evolving field of geroscience. Together, they dive deep into topics like the relationship between healthspan and lifespan, evaluating interventions like rapamycin and senolytics, the role of epigenetic changes in aging, and whether GLP-1 receptor agonists hold geroprotective potential. They also tackle major challenges in funding and public acceptance of longevity research including how geroprotective interventions might be tested in humans. Packed with nuanced debate, humor, and groundbreaking insights, this episode is a must-listen for anyone fascinated by the science of aging. View show notes here: https://bit.ly/4jpjjj8 Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ We discuss: 0:00:00 - Intro 0:01:07 - The recent rise in public interest in longevity, misconceptions, and the link between healthspan and lifespan 0:10:54 - Redefining healthspan, the US healthcare paradox, and separating longevity science from commercial hype 0:20:48 - The need to redirect medical research from disease-specific models to aging-focused approaches 0:30:19 - Proactive healthcare: rethinking health, disease, and the role of aging 0:35:36 - Biologic age versus chronologic age, and the limitations and potential of epigenetic clocks 0:51:42 - The utility and drawbacks of the “hallmarks of aging” as a framework for research and funding 0:59:22 - The role of epigenetic changes in aging and the challenges of proving causality 1:07:08 - The translational challenges of moving aging research from preclinical studies to human applications 1:22:23 - Distinguishing between a biomarker of aging and aging rate indicators 1:26:32 - The difficulties of translating longevity research in mice to humans, and the diff https://www.youtube-nocookie.com/embed/NU98SXBCjz4 10501 2025-01-27T05:10:00.000Z 2026-10-22T18:43:11.843Z https://longevityharbor.com/de/watch/NU98SXBCjz4 333 ‒ Longevity roundtable—the science of aging, geroprotective molecules, & lifestyle interventions https://i.ytimg.com/vi/NU98SXBCjz4/hqdefault.jpg In this special episode of The Drive, Peter introduces a brand-new roundtable format. Joined by three renowned experts in longevity science—Steven Austad, Richard Miller, and Matt Kaeberlein—the group explores the rapidly evolving field of geroscience. Together, they dive deep into topics like the relationship between healthspan and lifespan, evaluating interventions like rapamycin and senolytics, the role of epigenetic changes in aging, and whether GLP-1 receptor agonists hold geroprotective potential. They also tackle major challenges in funding and public acceptance of longevity research including how geroprotective interventions might be tested in humans. Packed with nuanced debate, humor, and groundbreaking insights, this episode is a must-listen for anyone fascinated by the science of aging. View show notes here: https://bit.ly/4jpjjj8 Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ We discuss: 0:00:00 - Intro 0:01:07 - The recent rise in public interest in longevity, misconceptions, and the link between healthspan and lifespan 0:10:54 - Redefining healthspan, the US healthcare paradox, and separating longevity science from commercial hype 0:20:48 - The need to redirect medical research from disease-specific models to aging-focused approaches 0:30:19 - Proactive healthcare: rethinking health, disease, and the role of aging 0:35:36 - Biologic age versus chronologic age, and the limitations and potential of epigenetic clocks 0:51:42 - The utility and drawbacks of the “hallmarks of aging” as a framework for research and funding 0:59:22 - The role of epigenetic changes in aging and the challenges of proving causality 1:07:08 - The translational challenges of moving aging research from preclinical studies to human applications 1:22:23 - Distinguishing between a biomarker of aging and aging rate indicators 1:26:32 - The difficulties of translating longevity research in mice to humans, and the diff https://www.youtube-nocookie.com/embed/NU98SXBCjz4 10501 2025-01-27T05:10:00.000Z 2026-10-22T18:43:11.843Z https://longevityharbor.com/en/watch/NX5WvmzfDck The Truth About Fasting for Women | Dr. Stacy Sims & Dr. Andrew Huberman https://i.ytimg.com/vi/NX5WvmzfDck/hqdefault.jpg Dr. Stacy Sims & Dr. Andrew Huberman discuss whether intermittent fasting is healthy for women, how it impacts their mental health and metabolism, & alternative weight management strategies. Dr. Stacy Sims, Ph.D., is an exercise physiologist, nutrition scientist, and expert in female-specific nutrition and training for health, performance, and longevity. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast. Watch the full episode: https://www.youtube.com/watch?v=pZX8ikmWvEU Show notes: https://www.hubermanlab.com/episode/dr-stacy-sims-female-specific-exercise-nutrition-for-health-performance-longevity *Timestamps* 00:00 Is Intermittent Fasting Different for Women vs Men? 01:24 Why Fasting is Non-ideal for Women's Metabolism 03:40 Timing Your Nutrition by Circadian Rhythm 04:56 Meal Timing & Cortisol 06:48 Female Exercise & Intermittent Fasting Relationship #HubermanLab #womenshealth #health #science #StacySims Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer https://www.youtube-nocookie.com/embed/NX5WvmzfDck 548 2025-03-29T15:30:26.000Z 2026-10-22T19:32:32.068Z https://longevityharbor.com/de/watch/NX5WvmzfDck The Truth About Fasting for Women | Dr. Stacy Sims & Dr. Andrew Huberman https://i.ytimg.com/vi/NX5WvmzfDck/hqdefault.jpg Dr. Stacy Sims & Dr. Andrew Huberman discuss whether intermittent fasting is healthy for women, how it impacts their mental health and metabolism, & alternative weight management strategies. Dr. Stacy Sims, Ph.D., is an exercise physiologist, nutrition scientist, and expert in female-specific nutrition and training for health, performance, and longevity. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast. Watch the full episode: https://www.youtube.com/watch?v=pZX8ikmWvEU Show notes: https://www.hubermanlab.com/episode/dr-stacy-sims-female-specific-exercise-nutrition-for-health-performance-longevity *Timestamps* 00:00 Is Intermittent Fasting Different for Women vs Men? 01:24 Why Fasting is Non-ideal for Women's Metabolism 03:40 Timing Your Nutrition by Circadian Rhythm 04:56 Meal Timing & Cortisol 06:48 Female Exercise & Intermittent Fasting Relationship #HubermanLab #womenshealth #health #science #StacySims Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer https://www.youtube-nocookie.com/embed/NX5WvmzfDck 548 2025-03-29T15:30:26.000Z 2026-10-22T19:32:32.068Z https://longevityharbor.com/en/watch/NY7Yab-lZmQ Epigenetic clocks respond to interventions, but that does not prove slower aging https://i.ytimg.com/vi/NY7Yab-lZmQ/hqdefault.jpg A pooled analysis of 51 human intervention studies found that epigenetic clocks, especially newer ones predicting mortality and pace of aging, respond to interventions. The authors do not claim that a moving clock proves an intervention slows aging. https://www.youtube-nocookie.com/embed/NY7Yab-lZmQ 93 2026-10-14T12:00:13.000Z 2026-10-22T19:54:47.370Z https://longevityharbor.com/de/watch/NY7Yab-lZmQ Epigenetische Uhren reagieren auf Interventionen, das belegt aber keine Verlangsamung des Alterns https://i.ytimg.com/vi/NY7Yab-lZmQ/hqdefault.jpg Eine gepoolte Auswertung von 51 Human-Interventionsstudien fand, dass epigenetische Uhren auf Interventionen reagieren, besonders neuere Uhren zur Vorhersage von Sterblichkeit und Alterungstempo. Die Autoren behaupten nicht, dass eine sich verändernde Uhr eine Verlangsamung des Alterns belegt. https://www.youtube-nocookie.com/embed/NY7Yab-lZmQ 93 2026-10-14T12:00:13.000Z 2026-10-22T19:54:47.370Z https://longevityharbor.com/en/watch/NcdT2O6a0cs Journal Club January 2020 - Rapamycin for Skin Aging https://i.ytimg.com/vi/NcdT2O6a0cs/hqdefault.jpg Dr. Oliver Medvedik hosts the January 2020 edition of Journal Club, our monthly livestreamed event where we review and discuss the latest scientific research publications relating to life extension and aging. This month's topic is a paper on rapamycin's beneficial effects on skin aging, including its effects on collagen and the method by which it can be administered. ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a Lifespan Hero: http://lifespan.io/hero #Aging #Science #Lifespan #Rejuvenation #Medicine #Biotechnology #Biotech #Gerontology #LifespanIO #JournalClub #Rapamycin https://www.youtube-nocookie.com/embed/NcdT2O6a0cs 3632 2020-02-05T19:17:04.000Z 2026-10-22T17:43:41.108Z https://longevityharbor.com/de/watch/NcdT2O6a0cs Journal Club January 2020 - Rapamycin for Skin Aging https://i.ytimg.com/vi/NcdT2O6a0cs/hqdefault.jpg Dr. Oliver Medvedik hosts the January 2020 edition of Journal Club, our monthly livestreamed event where we review and discuss the latest scientific research publications relating to life extension and aging. This month's topic is a paper on rapamycin's beneficial effects on skin aging, including its effects on collagen and the method by which it can be administered. ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a Lifespan Hero: http://lifespan.io/hero #Aging #Science #Lifespan #Rejuvenation #Medicine #Biotechnology #Biotech #Gerontology #LifespanIO #JournalClub #Rapamycin https://www.youtube-nocookie.com/embed/NcdT2O6a0cs 3632 2020-02-05T19:17:04.000Z 2026-10-22T17:43:41.108Z https://longevityharbor.com/en/watch/NcyDE2VqAjQ Scientists Won a Nobel Prize for This — 12 Anti Aging Foods That Help Your Cells Protect Their DNA https://i.ytimg.com/vi/NcyDE2VqAjQ/hqdefault.jpg In 2015, three scientists won the Nobel Prize in Chemistry for showing how your cells repair their DNA. Tomas Lindahl, Paul Modrich and Aziz Sancar mapped three repair kits: one for everyday wear, one for sun damage, and one for copying mistakes. In a study of 135 healthy people, the sun-damage kit in blood cells worked about 0.6% less well each year from age 20 to 60. Here are 12 everyday anti aging foods that help your cells protect their DNA, from red bell pepper to green tea, with what the human studies found and how strong the evidence is. In this video: • The three DNA repair kits behind the 2015 Nobel Prize • Why folate matters: it's how your cells make the DNA letter T • Four foods tested in human trials that measured DNA damage • The only food where scientists saw a repair enzyme become more active • A simple day with these foods THE 12 FOODS 1. Red bell pepper (152 mg vitamin C in one medium pepper) 2. Butternut squash (about 9 mg beta-carotene per cup, baked) 3. Sweet potato (about 13 mg beta-carotene: the most on the list) 4. Beets (136 µg folate per cup) 5. Chickpeas (282 µg folate per cup) 6. Black-eyed peas (356 µg folate per cup) 7. Beef liver: a small portion, about 2 oz, once a week (40 µg vitamin B12) 8. Lentils (358 µg folate per cup: the most on the list) 9. Purple grape juice, 100% juice (small 8-week trial: 26% less DNA damage) 10. Carrots (small 2-week carrot juice study, no comparison group) 11. Watercress (8-week trial, 85 g a day: 17% less DNA damage) 12. Green tea, 2 cups a day (three small trials from one lab; a repair enzyme was more active) The daily folate amount for adults is 400 µg. CHAPTERS 0:00 The Nobel Prize for DNA repair 0:57 #12 Red bell pepper 2:30 #11 Butternut squash 3:34 #10 Sweet potato 4:39 #9 Beets 5:48 #8 Chickpeas 6:45 #7 Black-eyed peas 7:50 Inside the three repair kits 10:06 #6 Beef liver (a small portion) 11:31 #5 Lentils 12:52 #4 Purple grape juice 13:55 #3 Carrots 15:10 #2 Watercress 16:28 #1 Green tea 18:31 A simple day with these foods 19:28 The full li https://www.youtube-nocookie.com/embed/NcyDE2VqAjQ 1250 2026-10-19T18:01:57.000Z 2026-10-22T19:54:19.502Z https://longevityharbor.com/de/watch/NcyDE2VqAjQ Scientists Won a Nobel Prize for This — 12 Anti Aging Foods That Help Your Cells Protect Their DNA https://i.ytimg.com/vi/NcyDE2VqAjQ/hqdefault.jpg In 2015, three scientists won the Nobel Prize in Chemistry for showing how your cells repair their DNA. Tomas Lindahl, Paul Modrich and Aziz Sancar mapped three repair kits: one for everyday wear, one for sun damage, and one for copying mistakes. In a study of 135 healthy people, the sun-damage kit in blood cells worked about 0.6% less well each year from age 20 to 60. Here are 12 everyday anti aging foods that help your cells protect their DNA, from red bell pepper to green tea, with what the human studies found and how strong the evidence is. In this video: • The three DNA repair kits behind the 2015 Nobel Prize • Why folate matters: it's how your cells make the DNA letter T • Four foods tested in human trials that measured DNA damage • The only food where scientists saw a repair enzyme become more active • A simple day with these foods THE 12 FOODS 1. Red bell pepper (152 mg vitamin C in one medium pepper) 2. Butternut squash (about 9 mg beta-carotene per cup, baked) 3. Sweet potato (about 13 mg beta-carotene: the most on the list) 4. Beets (136 µg folate per cup) 5. Chickpeas (282 µg folate per cup) 6. Black-eyed peas (356 µg folate per cup) 7. Beef liver: a small portion, about 2 oz, once a week (40 µg vitamin B12) 8. Lentils (358 µg folate per cup: the most on the list) 9. Purple grape juice, 100% juice (small 8-week trial: 26% less DNA damage) 10. Carrots (small 2-week carrot juice study, no comparison group) 11. Watercress (8-week trial, 85 g a day: 17% less DNA damage) 12. Green tea, 2 cups a day (three small trials from one lab; a repair enzyme was more active) The daily folate amount for adults is 400 µg. CHAPTERS 0:00 The Nobel Prize for DNA repair 0:57 #12 Red bell pepper 2:30 #11 Butternut squash 3:34 #10 Sweet potato 4:39 #9 Beets 5:48 #8 Chickpeas 6:45 #7 Black-eyed peas 7:50 Inside the three repair kits 10:06 #6 Beef liver (a small portion) 11:31 #5 Lentils 12:52 #4 Purple grape juice 13:55 #3 Carrots 15:10 #2 Watercress 16:28 #1 Green tea 18:31 A simple day with these foods 19:28 The full li https://www.youtube-nocookie.com/embed/NcyDE2VqAjQ 1250 2026-10-19T18:01:57.000Z 2026-10-22T19:54:19.502Z https://longevityharbor.com/en/watch/Nd_LktFpMMU Episode #5 - Professor Alexandra Stolzing: Working hard to get us to longevity escape velocity https://i.ytimg.com/vi/Nd_LktFpMMU/hqdefault.jpg 🚀 Detailed show notes are available in the LEVITY newsletter: https://peterottsjo.beehiiv.com/ 🚀 Don't forget to SUBSCRIBE to our channel: https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA?sub_confirmation=1 🚀 Looking for LEVITY Merch? https://levity-7.creator-spring.com/ Professor Alexandra Stolzing is a pioneer in biogerontological engineering at Loughborough University. With over two decades of experience, and as the former Vice President of Research at SENS Research Foundation, Prof. Stolzing shares insights on: Targeting senescent cells for anti-aging therapies Revolutionizing cryopreservation techniques Developing breath-based aging biomarkers Harnessing AI for rapid drug discovery in aging research Classifying aging as a disease The Longevity Biotech Fellowship Learn how her journey from Germany to the UK shaped her multidisciplinary approach to solving aging. Discover the challenges and opportunities in longevity research, including the critical need for basic science funding. ------------------------------------------------------------ ------------------------------------------------------------ ⏰⏰ CHAPTERS ⏰⏰ 00:00 Introduction 02:10 When Will We Reach Longevity Escape Velocity? 03:11 Background and Interdisciplinary Approach 05:05 Alexandra is a Generalist in Aging Biology 07:04 How Alexandra Decides What to Focus on 09:38 "Enjoyable to be Alive" - Why Alexandra Became a Biogerontologist 14:22 "I Never Thought About Giving Up" 16:48 Sens Research Foundation and the Repair Approach 20:36 Cellular Garbage 25:38 Loss of Stem Cells 26:53 How Important are Mitochondria? 28:33 Hallmarks of Aging 32:44 Bombarding the Public With Promises 36:03 Current Work on Senescent Cells 40:33 The Good and The Bad of Senescent Cells 43:16 When Can We Expect to Have Senolytics on The Market? 45:45 Importance of Biomarkers 47:44 Breath-Based Biomarkers 54:59 The Role AI Can Play 56:33 Large Language Model for Protein Discovery 01:00:32 Challenges in Cryopreservation and Cryoprotectants 01:21:19 Better Model https://www.youtube-nocookie.com/embed/Nd_LktFpMMU 6880 2024-08-06T03:00:26.000Z 2026-10-22T19:54:20.498Z https://longevityharbor.com/de/watch/Nd_LktFpMMU Episode #5 - Professor Alexandra Stolzing: Working hard to get us to longevity escape velocity https://i.ytimg.com/vi/Nd_LktFpMMU/hqdefault.jpg 🚀 Detailed show notes are available in the LEVITY newsletter: https://peterottsjo.beehiiv.com/ 🚀 Don't forget to SUBSCRIBE to our channel: https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA?sub_confirmation=1 🚀 Looking for LEVITY Merch? https://levity-7.creator-spring.com/ Professor Alexandra Stolzing is a pioneer in biogerontological engineering at Loughborough University. With over two decades of experience, and as the former Vice President of Research at SENS Research Foundation, Prof. Stolzing shares insights on: Targeting senescent cells for anti-aging therapies Revolutionizing cryopreservation techniques Developing breath-based aging biomarkers Harnessing AI for rapid drug discovery in aging research Classifying aging as a disease The Longevity Biotech Fellowship Learn how her journey from Germany to the UK shaped her multidisciplinary approach to solving aging. Discover the challenges and opportunities in longevity research, including the critical need for basic science funding. ------------------------------------------------------------ ------------------------------------------------------------ ⏰⏰ CHAPTERS ⏰⏰ 00:00 Introduction 02:10 When Will We Reach Longevity Escape Velocity? 03:11 Background and Interdisciplinary Approach 05:05 Alexandra is a Generalist in Aging Biology 07:04 How Alexandra Decides What to Focus on 09:38 "Enjoyable to be Alive" - Why Alexandra Became a Biogerontologist 14:22 "I Never Thought About Giving Up" 16:48 Sens Research Foundation and the Repair Approach 20:36 Cellular Garbage 25:38 Loss of Stem Cells 26:53 How Important are Mitochondria? 28:33 Hallmarks of Aging 32:44 Bombarding the Public With Promises 36:03 Current Work on Senescent Cells 40:33 The Good and The Bad of Senescent Cells 43:16 When Can We Expect to Have Senolytics on The Market? 45:45 Importance of Biomarkers 47:44 Breath-Based Biomarkers 54:59 The Role AI Can Play 56:33 Large Language Model for Protein Discovery 01:00:32 Challenges in Cryopreservation and Cryoprotectants 01:21:19 Better Model https://www.youtube-nocookie.com/embed/Nd_LktFpMMU 6880 2024-08-06T03:00:26.000Z 2026-10-22T19:54:20.498Z https://longevityharbor.com/en/watch/NeTTrmnHswo PhenoAge: biomarker-based biological age and mortality in a 2018 Aging paper https://i.ytimg.com/vi/NeTTrmnHswo/hqdefault.jpg The description presents PhenoAge, a calculator built from nine standard blood biomarkers plus chronological age, and says a younger biological than calendar age was linked to lower all-cause mortality. https://www.youtube-nocookie.com/embed/NeTTrmnHswo 669 2026-09-02T21:42:40.000Z 2026-10-22T22:30:58.814Z https://longevityharbor.com/de/watch/NeTTrmnHswo PhenoAge: biomarkerisches biologisches Alter und Sterblichkeit in einer Arbeit von 2018 in Aging https://i.ytimg.com/vi/NeTTrmnHswo/hqdefault.jpg Die Beschreibung stellt PhenoAge vor, einen Rechner aus neun Standard-Blutbiomarkern plus kalendarischem Alter, und nennt ein jüngeres biologisches als kalendarisches Alter mit niedrigerer Gesamtsterblichkeit verbunden. https://www.youtube-nocookie.com/embed/NeTTrmnHswo 669 2026-09-02T21:42:40.000Z 2026-10-22T22:30:58.814Z https://longevityharbor.com/en/watch/NedrVplkmhg Video description: meal timing, circadian rhythm and hormones in women 40+ https://i.ytimg.com/vi/NedrVplkmhg/hqdefault.jpg The description says this clip asks whether intermittent fasting harms energy, cravings and sleep in women 40+, and links disrupted circadian rhythm and hormone pulses to delaying food until late morning, especially in perimenopause. https://www.youtube-nocookie.com/embed/NedrVplkmhg 669 2026-05-30T14:00:03.000Z 2026-10-23T00:18:14.662Z https://longevityharbor.com/de/watch/NedrVplkmhg Videobeschreibung: Essenszeiten, circadianer Rhythmus und Hormone bei Frauen ab 40 https://i.ytimg.com/vi/NedrVplkmhg/hqdefault.jpg Laut Beschreibung fragt dieser Clip, ob intermittierendes Fasten Energie, Heißhunger und Schlaf bei Frauen ab 40 beeinträchtigt, und verknüpft gestörten circadianen Rhythmus und Hormonpulse mit dem Aufschieben von Essen bis zum späten Vormittag, besonders in der Perimenopause. https://www.youtube-nocookie.com/embed/NedrVplkmhg 669 2026-05-30T14:00:03.000Z 2026-10-23T00:18:14.662Z https://longevityharbor.com/en/watch/Nese1-h_JBw Video description: leg strength, sarcopenia and chair stands after 60 https://i.ytimg.com/vi/Nese1-h_JBw/hqdefault.jpg The description says walking alone may leave out leg strength, explains age-related muscle loss and presents a slow chair stand routine; it cites studies but reports no results. https://www.youtube-nocookie.com/embed/Nese1-h_JBw 908 2026-10-02T02:33:53.000Z 2026-10-22T21:31:13.616Z https://longevityharbor.com/de/watch/Nese1-h_JBw Videobeschreibung: Beinkraft, Sarkopenie und Stuhl-Aufstehen ab 60 https://i.ytimg.com/vi/Nese1-h_JBw/hqdefault.jpg Laut Beschreibung lässt Gehen allein die Beinkraft womöglich außen vor; sie erklärt altersassoziierten Muskelverlust und eine langsame Stuhl-Aufsteh-Übung, nennt Studien aber ohne Ergebnisse. https://www.youtube-nocookie.com/embed/Nese1-h_JBw 908 2026-10-02T02:33:53.000Z 2026-10-22T21:31:13.616Z https://longevityharbor.com/en/watch/NlCG13sg44Q Keynote proposes digital biomarkers for measuring ageing https://i.ytimg.com/vi/NlCG13sg44Q/hqdefault.jpg In this Milan Longevity Summit 2026 keynote description, Andrea Maier is said to explore digital biomarkers from wearables, smartphones and AI as tools for measuring ageing and supporting healthy ageing. https://www.youtube-nocookie.com/embed/NlCG13sg44Q 1466 2026-08-08T09:33:02.000Z 2026-10-22T23:08:50.173Z https://longevityharbor.com/de/watch/NlCG13sg44Q Keynote schlägt digitale Biomarker zur Messung des Alterns vor https://i.ytimg.com/vi/NlCG13sg44Q/hqdefault.jpg In der Beschreibung der Keynote beim Milan Longevity Summit 2026 soll Andrea Maier digitale Biomarker aus Wearables, Smartphones und KI als Werkzeuge zur Messung des Alterns und für gesundes Altern erkunden. https://www.youtube-nocookie.com/embed/NlCG13sg44Q 1466 2026-08-08T09:33:02.000Z 2026-10-22T23:08:50.173Z https://longevityharbor.com/en/watch/NnSZXijO7ek Video description: exercises for leg strength in people aged 55 and over https://i.ytimg.com/vi/NnSZXijO7ek/hqdefault.jpg The description says walking alone does not suffice for leg strength in older people and presents three exercises plus a 10-minute routine for people aged 55 and over. It attributes these claims to the video and gives no study data. https://www.youtube-nocookie.com/embed/NnSZXijO7ek 671 2026-01-21T09:00:27.000Z 2026-10-23T02:48:48.739Z https://longevityharbor.com/de/watch/NnSZXijO7ek Videobeschreibung: Übungen für Beinkraft bei Menschen ab 55 https://i.ytimg.com/vi/NnSZXijO7ek/hqdefault.jpg Die Beschreibung sagt, Gehen allein reiche für die Beinkraft älterer Menschen nicht aus, und stellt drei Übungen sowie eine 10-Minuten-Routine für Menschen ab 55 vor. Sie schreibt diese Aussagen dem Video zu und nennt keine Studiendaten. https://www.youtube-nocookie.com/embed/NnSZXijO7ek 671 2026-01-21T09:00:27.000Z 2026-10-23T02:48:48.739Z https://longevityharbor.com/en/watch/Nu1sIIZvJ8k Slow Down the Aging Process: Telomere Biology in Age-Management Medicine https://i.ytimg.com/vi/Nu1sIIZvJ8k/hqdefault.jpg Join me as I chat with Dr. Joseph Raffaele, a leading expert in age management and telomere biology. In this episode, we dive deep into the fascinating world of telomeres and their role in the aging process. Dr. Raffaele explains how his groundbreaking work with PhysioAge Systems is changing the game in age management, offering insights into how telomere length, epigenetics, and cellular changes can be monitored to extend longevity and vitality. We also explore how these scientific discoveries are influencing personalized health strategies for aging gracefully. Follow Us On Social Media: IG: https://www.instagram.com/holtorfmedicalgroup FB: https://facebook.com/holtorfmed ---- Connect with Dr. Joseph: Linkedin: https://www.linkedin.com/in/joseph-raffaele-md-56105a28/ Instagram: https://www.instagram.com/raffaelemd/?hl=en Three Takeaways ✅The Nine Hallmarks of Aging: Discover how telomeres, epigenetics, and cellular senescence contribute to aging and how to target these factors for better longevity. ✅Telomere Length and Health: Understand the crucial role of telomere length in cancer risk, hormone optimization, and cellular regeneration. ✅Personalized Health: Learn why individualized approaches like growth hormone therapy and IGF-1 regulation are essential for optimizing telomere health. About the Guest Dr. Joseph Raffaele is a leader in age management medicine and a co-founder of PhysioAge Medical Group. He is a renowned expert in clinical telomere biology and has contributed extensively to research on aging. Dr. Raffaele earned his BA from Princeton and his MD from Drexel University Medical Center, and completed his training at NYU and Cornell. He is board-certified in internal medicine and anti-aging medicine. #Longevity #Biohacking #holtorfmedicalgroup #telomere #Biology https://www.youtube-nocookie.com/embed/Nu1sIIZvJ8k 3961 2025-06-25T20:00:14.000Z 2026-10-22T19:32:33.500Z https://longevityharbor.com/de/watch/Nu1sIIZvJ8k Slow Down the Aging Process: Telomere Biology in Age-Management Medicine https://i.ytimg.com/vi/Nu1sIIZvJ8k/hqdefault.jpg Join me as I chat with Dr. Joseph Raffaele, a leading expert in age management and telomere biology. In this episode, we dive deep into the fascinating world of telomeres and their role in the aging process. Dr. Raffaele explains how his groundbreaking work with PhysioAge Systems is changing the game in age management, offering insights into how telomere length, epigenetics, and cellular changes can be monitored to extend longevity and vitality. We also explore how these scientific discoveries are influencing personalized health strategies for aging gracefully. Follow Us On Social Media: IG: https://www.instagram.com/holtorfmedicalgroup FB: https://facebook.com/holtorfmed ---- Connect with Dr. Joseph: Linkedin: https://www.linkedin.com/in/joseph-raffaele-md-56105a28/ Instagram: https://www.instagram.com/raffaelemd/?hl=en Three Takeaways ✅The Nine Hallmarks of Aging: Discover how telomeres, epigenetics, and cellular senescence contribute to aging and how to target these factors for better longevity. ✅Telomere Length and Health: Understand the crucial role of telomere length in cancer risk, hormone optimization, and cellular regeneration. ✅Personalized Health: Learn why individualized approaches like growth hormone therapy and IGF-1 regulation are essential for optimizing telomere health. About the Guest Dr. Joseph Raffaele is a leader in age management medicine and a co-founder of PhysioAge Medical Group. He is a renowned expert in clinical telomere biology and has contributed extensively to research on aging. Dr. Raffaele earned his BA from Princeton and his MD from Drexel University Medical Center, and completed his training at NYU and Cornell. He is board-certified in internal medicine and anti-aging medicine. #Longevity #Biohacking #holtorfmedicalgroup #telomere #Biology https://www.youtube-nocookie.com/embed/Nu1sIIZvJ8k 3961 2025-06-25T20:00:14.000Z 2026-10-22T19:32:33.500Z https://longevityharbor.com/en/watch/O405ct2XVmE Video description: Dr. Eisen presents mTOR as a central longevity pathway https://i.ytimg.com/vi/O405ct2XVmE/hqdefault.jpg In the description, Dr. Roger Eisen, senior physician at MY MAYR MED Resort, presents mTOR as a key pathway in aging, cell regeneration and energy metabolism and says it can be supported to stay healthier and vital longer. The description gives no study data. https://www.youtube-nocookie.com/embed/O405ct2XVmE 118 2026-03-04T08:00:33.000Z 2026-10-23T02:17:32.843Z https://longevityharbor.com/de/watch/O405ct2XVmE Videobeschreibung: Dr. Eisen stellt mTOR als zentralen Langlebigkeitspfad vor https://i.ytimg.com/vi/O405ct2XVmE/hqdefault.jpg In der Beschreibung stellt Dr. Roger Eisen, leitender Arzt im MY MAYR MED Resort, mTOR als Schlüsselpfad beim Altern, bei der Zellregeneration und im Energiestoffwechsel vor und sagt, man könne ihn gezielt unterstützen, um gesünder und langfristig vital zu bleiben. Die Beschreibung nennt keine Studiendaten. https://www.youtube-nocookie.com/embed/O405ct2XVmE 118 2026-03-04T08:00:33.000Z 2026-10-23T02:17:32.843Z https://longevityharbor.com/en/watch/O67pvKxio10 272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more https://i.ytimg.com/vi/O67pvKxio10/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Peter welcomes guests David Sabatini & Matt Kaeberlein, two world-leading experts on rapamycin & mTOR. David & Matt begin by telling the fascinating story of the discovery of rapamycin & its brief history as a pharmacological agent in humans. They then unravel the function of mTOR, a central regulator of numerous biological processes, & they discuss the pathways through which rapamycin exerts its potential benefits on lifespan. They touch upon initial studies that suggested rapamycin may have geroprotective effects & the ongoing research that continues to shed light on this unique molecule. Furthermore, they discuss the elusive details surrounding the frequency & dosing of rapamycin use in humans, & Peter emphasizes his reservations about indiscriminately prescribing rapamycin as a longevity drug for patients. We discuss: 0:00:00-Intro 0:01:00-David & Matt’s expertise in mTOR & rapamycin 0:12:00-The discovery of rapamycin & first use in humans as an immunosuppressant 0:19:05-Emergence of rapamycin as a molecule with the potential to prolong lifespan 0:25:53-Groundbreaking rapamycin study on mouse lifespan extension & the open questions about the timing & frequency of dosing 0:36:26-Explaining mTOR & the biology behind rapamycin’s effects 0:47:13-Differences in how rapamycin inhibits mTOR complex 1 (MTORC1) versus mTOR complex 2 (MTORC2) 0:51:20-Reconciling the biochemical mechanism of rapamycin with its longevity benefit 0:56:42-Important discoveries about the interplay of amino acids (leucine in particular) & mTOR 1:04:43-Reconciling rapamycin-mediated mTOR inhibition with mTOR's significance in building & maintaining muscle 1:12:00-Unanswered questions around the tissue specificity of rapamycin 1:18:09-Rapamycin’s ability to cross the blood-brain barrier & its potential impacts on https://www.youtube-nocookie.com/embed/O67pvKxio10 10889 2023-09-25T07:30:04.000Z 2026-10-22T17:43:41.738Z https://longevityharbor.com/de/watch/O67pvKxio10 272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more https://i.ytimg.com/vi/O67pvKxio10/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Peter welcomes guests David Sabatini & Matt Kaeberlein, two world-leading experts on rapamycin & mTOR. David & Matt begin by telling the fascinating story of the discovery of rapamycin & its brief history as a pharmacological agent in humans. They then unravel the function of mTOR, a central regulator of numerous biological processes, & they discuss the pathways through which rapamycin exerts its potential benefits on lifespan. They touch upon initial studies that suggested rapamycin may have geroprotective effects & the ongoing research that continues to shed light on this unique molecule. Furthermore, they discuss the elusive details surrounding the frequency & dosing of rapamycin use in humans, & Peter emphasizes his reservations about indiscriminately prescribing rapamycin as a longevity drug for patients. We discuss: 0:00:00-Intro 0:01:00-David & Matt’s expertise in mTOR & rapamycin 0:12:00-The discovery of rapamycin & first use in humans as an immunosuppressant 0:19:05-Emergence of rapamycin as a molecule with the potential to prolong lifespan 0:25:53-Groundbreaking rapamycin study on mouse lifespan extension & the open questions about the timing & frequency of dosing 0:36:26-Explaining mTOR & the biology behind rapamycin’s effects 0:47:13-Differences in how rapamycin inhibits mTOR complex 1 (MTORC1) versus mTOR complex 2 (MTORC2) 0:51:20-Reconciling the biochemical mechanism of rapamycin with its longevity benefit 0:56:42-Important discoveries about the interplay of amino acids (leucine in particular) & mTOR 1:04:43-Reconciling rapamycin-mediated mTOR inhibition with mTOR's significance in building & maintaining muscle 1:12:00-Unanswered questions around the tissue specificity of rapamycin 1:18:09-Rapamycin’s ability to cross the blood-brain barrier & its potential impacts on https://www.youtube-nocookie.com/embed/O67pvKxio10 10889 2023-09-25T07:30:04.000Z 2026-10-22T17:43:41.738Z https://longevityharbor.com/en/watch/O8BaiRfhL_I Age and Circadian Rhythm: Satchin Panda, PhD https://i.ytimg.com/vi/O8BaiRfhL_I/hqdefault.jpg What is our circadian rhythm and how does it impact our health? What time should we eat, exercise, and sleep? How does caffeine impact our circadian rhythm? What time of day does the brain work best? How does traveling impact our circadian rhythm? How are age and circadian rhythms connected? What are the five tips that can help us improve our circadian rhythm? How does the ICU impact circadian rhythms?  Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist (https://www.timelinenutrition.com/partners/ageist) .  LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST (http://drinklmnt.com/AGEIST) .  InsideTracker — the dashboard to your Inner Health. Listeners get 20% off on all products at InsideTracker.com/AGEIST (http://insidetracker.com/AGEIST) . Dr. Satchin Panda is a professor at The Salk Institute and author of the book The Circadian Code: Lose Weight, Supercharge Your Energy, and Transform Your Health from Morning to Midnight (https://fave.co/41siYDv) . He joins us to discuss circadian rhythm, what time we should eat, exercise, work, and sleep, how age impacts circadian rhythms, and more.  “Circadian rhythm is essentially the master plan that is already written into our DNA in every cell and if we follow this timetable then we can live a few years longer.”  “We are designed to eat more carbohydrates in the first half of the day, not in the second half of our day or late into the night.” “Our bodies are programmed with this timetable and we just have to follow it.”   “For people who are trying to control their blood pressure, who are trying to control their blood sugar with exercise, afternoon exercise tends to be more effective in reducing blood pressure and also controlling blood glucose much better than the identical exercise done in the morning.” https://www.youtube-nocookie.com/embed/O8BaiRfhL_I 4843 2023-11-17T19:54:00.000Z 2026-10-22T18:54:02.252Z https://longevityharbor.com/de/watch/O8BaiRfhL_I Age and Circadian Rhythm: Satchin Panda, PhD https://i.ytimg.com/vi/O8BaiRfhL_I/hqdefault.jpg What is our circadian rhythm and how does it impact our health? What time should we eat, exercise, and sleep? How does caffeine impact our circadian rhythm? What time of day does the brain work best? How does traveling impact our circadian rhythm? How are age and circadian rhythms connected? What are the five tips that can help us improve our circadian rhythm? How does the ICU impact circadian rhythms?  Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist (https://www.timelinenutrition.com/partners/ageist) .  LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST (http://drinklmnt.com/AGEIST) .  InsideTracker — the dashboard to your Inner Health. Listeners get 20% off on all products at InsideTracker.com/AGEIST (http://insidetracker.com/AGEIST) . Dr. Satchin Panda is a professor at The Salk Institute and author of the book The Circadian Code: Lose Weight, Supercharge Your Energy, and Transform Your Health from Morning to Midnight (https://fave.co/41siYDv) . He joins us to discuss circadian rhythm, what time we should eat, exercise, work, and sleep, how age impacts circadian rhythms, and more.  “Circadian rhythm is essentially the master plan that is already written into our DNA in every cell and if we follow this timetable then we can live a few years longer.”  “We are designed to eat more carbohydrates in the first half of the day, not in the second half of our day or late into the night.” “Our bodies are programmed with this timetable and we just have to follow it.”   “For people who are trying to control their blood pressure, who are trying to control their blood sugar with exercise, afternoon exercise tends to be more effective in reducing blood pressure and also controlling blood glucose much better than the identical exercise done in the morning.” https://www.youtube-nocookie.com/embed/O8BaiRfhL_I 4843 2023-11-17T19:54:00.000Z 2026-10-22T18:54:02.252Z https://longevityharbor.com/en/watch/O8gwzF_T3KY Nurse's video description: fasting, animal data and human lifespan claims https://i.ytimg.com/vi/O8gwzF_T3KY/hqdefault.jpg The description says the video examines fasting research, what animal studies show and where human research limits lifespan claims; the video itself was not reviewed. https://www.youtube-nocookie.com/embed/O8gwzF_T3KY 152 2026-09-12T22:26:23.000Z 2026-10-22T22:16:45.842Z https://longevityharbor.com/de/watch/O8gwzF_T3KY Video einer Pflegefachkraft: Fasten, Tierdaten und menschliche Lebensspannen-Aussagen https://i.ytimg.com/vi/O8gwzF_T3KY/hqdefault.jpg Laut Beschreibung prüft das Video Fastenforschung, was Tierstudien zeigen und wo die Forschung am Menschen Aussagen zur Lebensspanne begrenzt; das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/O8gwzF_T3KY 152 2026-09-12T22:26:23.000Z 2026-10-22T22:16:45.842Z https://longevityharbor.com/en/watch/OGeMmgQcSGc Video description lists seven supplements the creator links to healthy aging https://i.ytimg.com/vi/OGeMmgQcSGc/hqdefault.jpg The description says the creator presents seven supplements he believes support healthy aging and names the 12 hallmarks of aging; no study results are given. https://www.youtube-nocookie.com/embed/OGeMmgQcSGc 713 2026-08-02T15:00:00.000Z 2026-10-22T23:15:58.072Z https://longevityharbor.com/de/watch/OGeMmgQcSGc Videobeschreibung nennt sieben Nahrungsergänzungsmittel, die der Ersteller mit gesundem Altern verbi https://i.ytimg.com/vi/OGeMmgQcSGc/hqdefault.jpg Laut Beschreibung stellt der Ersteller sieben Nahrungsergänzungsmittel vor, die seiner Ansicht nach gesundes Altern unterstützen, und nennt die 12 Hallmarks des Alterns; Studienergebnisse werden nicht genannt. https://www.youtube-nocookie.com/embed/OGeMmgQcSGc 713 2026-08-02T15:00:00.000Z 2026-10-22T23:15:58.072Z https://longevityharbor.com/en/watch/OIRo_fcdq0A Fasting And Longevity | Jason Fung https://i.ytimg.com/vi/OIRo_fcdq0A/hqdefault.jpg Fasting And Longevity | Jason Fung 🕒 Unlock the Secrets of Fasting and Longevity: Maximize Your Lifespan with Calorie Restriction without Malnutrition. Discover how fasting can help you stay healthier, reduce body fat, combat hyperinsulinemia, promote apoptosis, and boost anabolic hormones. Learn about decreased inflammation through autophagy and mitophagy, harness the power of hormesis and xenormesis, and combat oxidative stress with intermittent fasting. Join us as we delve into the science of longevity and fasting.🔒 Join us on this enlightening journey into the science of fasting and its potential to maximize longevity. Hit the like button 👍, subscribe for more informative content, and ring the notification bell 🔔 to stay informed! 👉Join my membership for perks: https://www.youtube.com/channel/UCoyL4iGArWn5Hu0V_sAhK2w/join ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ ▶️ Timestamps / Chapters 0:00 Intro 0:17 Theories of ageing 1:00 The way of maximise Longevity 2:04 Calorie Restriction without Malnutrition 4:21 How Calorie restriction can help one to stay healthier? 4:33 Decreased the body fat 4:55 Apoptosis 5:44 Hyperinsulinemia 6:17 Anabolic Hormones 6:55 Decreased inflammation 7:38 Autophagy/Mitophagy 8:23 Hormesis/xenormesis 9:14 Oxidative stress 10:31 Intermittent fasting 11:41 Outro ============================= 📌 BOOKS: 👉 The Obesity Code - Reviewing underlying physiology of weight loss and how low carb diets and fasting can help. https://www.amazon.com/dp/1771641258?... 👉 The Diabetes Code - Reviewing how type 2 diabetes is a reversible disease and dietary strategies. https://www.amazon.com/dp/B0795BLS8D?... 👉 The Cancer Code - Scientific exploration of how cancer develops - https://www.amazon.com/dp/0062894005?... 📌 Amazon: 👉 USA - https://www.amazon.com/shop/jasonfung 👉 Canada - https://www.amazon.ca/shop/jasonfung ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ 📌 Please visit our :- 🔹 Website - https://www.doctorjasonfung.com 🔹 Blog- https://drjasonfung.medium.com 🔹 Community- https://www.thefastingmethod.com 🔹 Faceboo https://www.youtube-nocookie.com/embed/OIRo_fcdq0A 717 2022-02-20T15:45:01.000Z 2026-10-22T17:43:37.690Z https://longevityharbor.com/de/watch/OIRo_fcdq0A Fasting And Longevity | Jason Fung https://i.ytimg.com/vi/OIRo_fcdq0A/hqdefault.jpg Fasting And Longevity | Jason Fung 🕒 Unlock the Secrets of Fasting and Longevity: Maximize Your Lifespan with Calorie Restriction without Malnutrition. Discover how fasting can help you stay healthier, reduce body fat, combat hyperinsulinemia, promote apoptosis, and boost anabolic hormones. Learn about decreased inflammation through autophagy and mitophagy, harness the power of hormesis and xenormesis, and combat oxidative stress with intermittent fasting. Join us as we delve into the science of longevity and fasting.🔒 Join us on this enlightening journey into the science of fasting and its potential to maximize longevity. Hit the like button 👍, subscribe for more informative content, and ring the notification bell 🔔 to stay informed! 👉Join my membership for perks: https://www.youtube.com/channel/UCoyL4iGArWn5Hu0V_sAhK2w/join ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ ▶️ Timestamps / Chapters 0:00 Intro 0:17 Theories of ageing 1:00 The way of maximise Longevity 2:04 Calorie Restriction without Malnutrition 4:21 How Calorie restriction can help one to stay healthier? 4:33 Decreased the body fat 4:55 Apoptosis 5:44 Hyperinsulinemia 6:17 Anabolic Hormones 6:55 Decreased inflammation 7:38 Autophagy/Mitophagy 8:23 Hormesis/xenormesis 9:14 Oxidative stress 10:31 Intermittent fasting 11:41 Outro ============================= 📌 BOOKS: 👉 The Obesity Code - Reviewing underlying physiology of weight loss and how low carb diets and fasting can help. https://www.amazon.com/dp/1771641258?... 👉 The Diabetes Code - Reviewing how type 2 diabetes is a reversible disease and dietary strategies. https://www.amazon.com/dp/B0795BLS8D?... 👉 The Cancer Code - Scientific exploration of how cancer develops - https://www.amazon.com/dp/0062894005?... 📌 Amazon: 👉 USA - https://www.amazon.com/shop/jasonfung 👉 Canada - https://www.amazon.ca/shop/jasonfung ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ 📌 Please visit our :- 🔹 Website - https://www.doctorjasonfung.com 🔹 Blog- https://drjasonfung.medium.com 🔹 Community- https://www.thefastingmethod.com 🔹 Faceboo https://www.youtube-nocookie.com/embed/OIRo_fcdq0A 717 2022-02-20T15:45:01.000Z 2026-10-22T17:43:37.690Z https://longevityharbor.com/en/watch/OLqbrhReysw Nutrition talk: post-meal tiredness, blood sugar and processed foods https://i.ytimg.com/vi/OLqbrhReysw/hqdefault.jpg A conversation with Dr. Julia Berger covers nutrient-rich eating, tiredness after meals, blood sugar swings, snacks, protein shakes and highly processed 'healthy foods', plus what a healthy plate should look like. https://www.youtube-nocookie.com/embed/OLqbrhReysw 1115 2026-05-28T05:30:04.000Z 2026-10-23T00:19:02.404Z https://longevityharbor.com/de/watch/OLqbrhReysw Ernährungsgespräch: Müdigkeit nach dem Essen, Blutzucker und verarbeitete Lebensmittel https://i.ytimg.com/vi/OLqbrhReysw/hqdefault.jpg Ein Gespräch mit Dr. Julia Berger behandelt nährstoffreiche Ernährung, Müdigkeit nach dem Essen, Blutzuckerschwankungen, Snacks, Proteinshakes und hochverarbeitete „Healthy Foods“ sowie die Frage, wie ein wirklich gesunder Teller aussehen sollte. https://www.youtube-nocookie.com/embed/OLqbrhReysw 1115 2026-05-28T05:30:04.000Z 2026-10-23T00:19:02.404Z https://longevityharbor.com/en/watch/OPxFEnAluXo Video description maps 12 hallmarks of aging from a 2023 Cell review https://i.ytimg.com/vi/OPxFEnAluXo/hqdefault.jpg The description says the video explains the 2023 Cell paper that expanded the hallmarks of aging from nine to twelve and groups them into primary damage, antagonistic responses and integrative collapse. It is educational only and not medical advice. https://www.youtube-nocookie.com/embed/OPxFEnAluXo 422 2026-01-28T16:10:42.000Z 2026-10-23T02:45:54.061Z https://longevityharbor.com/de/watch/OPxFEnAluXo Videobeschreibung ordnet 12 Hallmarks des Alterns aus einer Cell-Übersicht von 2023 ein https://i.ytimg.com/vi/OPxFEnAluXo/hqdefault.jpg Laut Beschreibung erklärt das Video die Cell-Arbeit von 2023, die die Hallmarks des Alterns von neun auf zwölf erweiterte, und ordnet sie in primäre Schäden, antagonistische Reaktionen und integrativen Verfall. Es dient nur der Bildung und ist kein medizinischer Rat. https://www.youtube-nocookie.com/embed/OPxFEnAluXo 422 2026-01-28T16:10:42.000Z 2026-10-23T02:45:54.061Z https://longevityharbor.com/en/watch/OQfrknEqA7E Epigenetic Age of a 53 year old #epigenetic #clocks #aging https://i.ytimg.com/vi/OQfrknEqA7E/hqdefault.jpg Epigenetic Clocks have been developed to measure whole body biological age. They are Sub-Clinical because they have yet to be adopted by Clinicians worldwide. This means that compared to Clinical Gold Standard biomarkers they have to be weighted accordingly! #epigenetic #biomarkers #dnamethylation #clinical #workout #aging #antiaging #rejuvenation #agereversal #measurements #gym #50isthenew30 #6pack #6packabs #grimage #horvath #hannum #levine #clock #DunedinPACE #trudiagnostic https://www.youtube-nocookie.com/embed/OQfrknEqA7E 95 2025-05-01T11:00:37.000Z 2026-10-22T18:32:06.759Z https://longevityharbor.com/de/watch/OQfrknEqA7E Epigenetic Age of a 53 year old #epigenetic #clocks #aging https://i.ytimg.com/vi/OQfrknEqA7E/hqdefault.jpg Epigenetic Clocks have been developed to measure whole body biological age. They are Sub-Clinical because they have yet to be adopted by Clinicians worldwide. This means that compared to Clinical Gold Standard biomarkers they have to be weighted accordingly! #epigenetic #biomarkers #dnamethylation #clinical #workout #aging #antiaging #rejuvenation #agereversal #measurements #gym #50isthenew30 #6pack #6packabs #grimage #horvath #hannum #levine #clock #DunedinPACE #trudiagnostic https://www.youtube-nocookie.com/embed/OQfrknEqA7E 95 2025-05-01T11:00:37.000Z 2026-10-22T18:32:06.759Z https://longevityharbor.com/en/watch/OVPZ1HkJrvA USC|UCLA Geroscience Meeting Day 2 Afternoon https://i.ytimg.com/vi/OVPZ1HkJrvA/hqdefault.jpg USC|UCLA Geroscience Meeting: Integrating Social and Biological Hallmarks of Aging Day 2 Afternoon Physiological Health Age (PhysAge) the "interpretable" clock - Em Arpawong (00:00:00) The interplay between omics and outcome - Robert Leigh (00:23:12) Utilizing multi-omics and machine learning to investigate general - and system specific aging - Eric Klopack (00:44:43) Using Machine-Learning to Identify Differences in the Association between Blood-Based Biomarkers and Later Life Health Across Race and Ethnicity - Mateo Farina (01:04:46) https://www.youtube-nocookie.com/embed/OVPZ1HkJrvA 5073 2025-04-16T22:36:21.000Z 2026-10-22T18:32:11.623Z https://longevityharbor.com/de/watch/OVPZ1HkJrvA USC|UCLA Geroscience Meeting Day 2 Afternoon https://i.ytimg.com/vi/OVPZ1HkJrvA/hqdefault.jpg USC|UCLA Geroscience Meeting: Integrating Social and Biological Hallmarks of Aging Day 2 Afternoon Physiological Health Age (PhysAge) the "interpretable" clock - Em Arpawong (00:00:00) The interplay between omics and outcome - Robert Leigh (00:23:12) Utilizing multi-omics and machine learning to investigate general - and system specific aging - Eric Klopack (00:44:43) Using Machine-Learning to Identify Differences in the Association between Blood-Based Biomarkers and Later Life Health Across Race and Ethnicity - Mateo Farina (01:04:46) https://www.youtube-nocookie.com/embed/OVPZ1HkJrvA 5073 2025-04-16T22:36:21.000Z 2026-10-22T18:32:11.623Z https://longevityharbor.com/en/watch/OWsNTWXVt9A Video description on muscle loss after 60: protein, strength training, movement, sleep and nutrition https://i.ytimg.com/vi/OWsNTWXVt9A/hqdefault.jpg The description announces a video about why muscles can weaken with age and what may help after 60. It names protein for muscle maintenance, strength training, regular movement, sleep and recovery, diet and fluid intake, and signs prompting medical advice. No results are reported. https://www.youtube-nocookie.com/embed/OWsNTWXVt9A 1106 2026-10-12T16:35:36.000Z 2026-10-22T20:19:32.970Z https://longevityharbor.com/de/watch/OWsNTWXVt9A Videobeschreibung zu Muskelverlust ab 60: Eiweiß, Krafttraining, Bewegung, Schlaf und Ernährung https://i.ytimg.com/vi/OWsNTWXVt9A/hqdefault.jpg Die Beschreibung kündigt ein Video dazu an, warum Muskeln mit dem Alter schwächer werden können und was nach 60 helfen kann. Genannt werden Eiweiß für den Muskelerhalt, Krafttraining, regelmäßige Bewegung, Schlaf und Erholung, Ernährung und Flüssigkeitszufuhr sowie Anzeichen für ärztlichen Rat. Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/OWsNTWXVt9A 1106 2026-10-12T16:35:36.000Z 2026-10-22T20:19:32.970Z https://longevityharbor.com/en/watch/OdnHJ0hMJKI Why Do We Wake Up Earlier As We Age Explained by Science https://i.ytimg.com/vi/OdnHJ0hMJKI/hqdefault.jpg Find out in this video how aging impacts our sleep. Find out why biological changes result in earlier wake times and a weakened response to external cues form the brain and alters our circadian rhythms. We also discuss vision changes that limit light stimulation and affect the internal sleep-wake cycle. This one is a must see if you have an inquiring mind around sleep science, and the aging process. 🔍 Keywords: Aging & Sleep; Circadian Rhythms; Biological Changes; Vision changes, sleep science Don't forget to drop a like and share the video if you enjoyed it! #Genetic variation #AgingAndSleep #CircadianRhythms #healthyliving @10HealthBenefits OUTLINE: 00:00:00 Why Do We Wake Up Earlier As We Age? | Explained by Science ========================================================== Subscribe To Our YouTube Channel @10HealthBenefits ========================================================== MEDICAL DISCLAIMER This article is an instructional guide and in no way a replacement for qualified medical advice, diagnosis or treatment And, if you ever have any medical questions, be sure to talk with your healthcare provider. Please, however do not delay seeking professional medical advice or dismiss this one video altogether. Although we do our best to provide up-to-date and correct information, mistakes can occur for which MedicalDialogues.com is not responsible. Changes in medical practices will inevitably be introduced and it should always be independently verified if a particular clinical diagnosis or treatment is the most appropriate in each unique case https://www.youtube-nocookie.com/embed/OdnHJ0hMJKI 248 2024-11-23T11:00:23.000Z 2026-10-22T19:43:49.714Z https://longevityharbor.com/de/watch/OdnHJ0hMJKI Why Do We Wake Up Earlier As We Age Explained by Science https://i.ytimg.com/vi/OdnHJ0hMJKI/hqdefault.jpg Find out in this video how aging impacts our sleep. Find out why biological changes result in earlier wake times and a weakened response to external cues form the brain and alters our circadian rhythms. We also discuss vision changes that limit light stimulation and affect the internal sleep-wake cycle. This one is a must see if you have an inquiring mind around sleep science, and the aging process. 🔍 Keywords: Aging & Sleep; Circadian Rhythms; Biological Changes; Vision changes, sleep science Don't forget to drop a like and share the video if you enjoyed it! #Genetic variation #AgingAndSleep #CircadianRhythms #healthyliving @10HealthBenefits OUTLINE: 00:00:00 Why Do We Wake Up Earlier As We Age? | Explained by Science ========================================================== Subscribe To Our YouTube Channel @10HealthBenefits ========================================================== MEDICAL DISCLAIMER This article is an instructional guide and in no way a replacement for qualified medical advice, diagnosis or treatment And, if you ever have any medical questions, be sure to talk with your healthcare provider. Please, however do not delay seeking professional medical advice or dismiss this one video altogether. Although we do our best to provide up-to-date and correct information, mistakes can occur for which MedicalDialogues.com is not responsible. Changes in medical practices will inevitably be introduced and it should always be independently verified if a particular clinical diagnosis or treatment is the most appropriate in each unique case https://www.youtube-nocookie.com/embed/OdnHJ0hMJKI 248 2024-11-23T11:00:23.000Z 2026-10-22T19:43:49.714Z https://longevityharbor.com/en/watch/OsJEZeztUPY Heart Healthy Aging with Nutrition https://i.ytimg.com/vi/OsJEZeztUPY/hqdefault.jpg Like everything else in our bodies, the cardiovascular (CV) system goes through the aging process. We do know that there are things we can do, however, to positively impact our cardiovascular health. Watch this film to learn more about the aging of our CV system, research on bioactive compounds and how they may help maintain heart health, and a look at how cocoa flavanol supports healthy blood flow.   Learn more by going to agingresearch.org/NutritionFilms https://www.youtube-nocookie.com/embed/OsJEZeztUPY 277 2016-03-07T17:42:48.000Z 2026-10-23T01:53:57.286Z https://longevityharbor.com/de/watch/OsJEZeztUPY Heart Healthy Aging with Nutrition https://i.ytimg.com/vi/OsJEZeztUPY/hqdefault.jpg Like everything else in our bodies, the cardiovascular (CV) system goes through the aging process. We do know that there are things we can do, however, to positively impact our cardiovascular health. Watch this film to learn more about the aging of our CV system, research on bioactive compounds and how they may help maintain heart health, and a look at how cocoa flavanol supports healthy blood flow.   Learn more by going to agingresearch.org/NutritionFilms https://www.youtube-nocookie.com/embed/OsJEZeztUPY 277 2016-03-07T17:42:48.000Z 2026-10-23T01:53:57.286Z https://longevityharbor.com/en/watch/OuVsPj_ehSQ Description of a Nature transcriptome study on ageing clocks across four species https://i.ytimg.com/vi/OuVsPj_ehSQ/hqdefault.jpg The video description reports a Nature study of over 11,000 transcriptomes from mice, rats, macaques and humans that identified ageing hallmarks and gene-expression clocks linked to biological age and mortality. https://www.youtube-nocookie.com/embed/OuVsPj_ehSQ 364 2026-05-30T09:03:36.000Z 2026-10-23T00:18:22.465Z https://longevityharbor.com/de/watch/OuVsPj_ehSQ Beschreibung einer Nature-Transkriptomstudie zu Altersuhren bei vier Arten https://i.ytimg.com/vi/OuVsPj_ehSQ/hqdefault.jpg Die Videobeschreibung berichtet von einer Nature-Studie mit über 11.000 Transkriptomen von Mäusen, Ratten, Makaken und Menschen, die Altersmerkmale und Genexpressions-Uhren mit Bezug zu biologischem Alter und Sterblichkeit fand. https://www.youtube-nocookie.com/embed/OuVsPj_ehSQ 364 2026-05-30T09:03:36.000Z 2026-10-23T00:18:22.465Z https://longevityharbor.com/en/watch/OvlrcxwsR3M Epigenetic clocks: DNA methylation and biological age in a video description https://i.ytimg.com/vi/OvlrcxwsR3M/hqdefault.jpg The description says the video explains DNA methylation and epigenetic clocks, mentions the Dunedin Study, and notes that these biomarkers are not a crystal ball for future health. https://www.youtube-nocookie.com/embed/OvlrcxwsR3M 568 2026-08-31T01:31:29.000Z 2026-10-22T22:39:06.778Z https://longevityharbor.com/de/watch/OvlrcxwsR3M Epigenetische Uhren: DNA-Methylierung und biologisches Alter in einer Videobeschreibung https://i.ytimg.com/vi/OvlrcxwsR3M/hqdefault.jpg Laut Beschreibung erklärt das Video DNA-Methylierung und epigenetische Uhren, nennt die Dunedin-Studie und betont, dass diese Biomarker keine Kristallkugel für die künftige Gesundheit sind. https://www.youtube-nocookie.com/embed/OvlrcxwsR3M 568 2026-08-31T01:31:29.000Z 2026-10-22T22:39:06.778Z https://longevityharbor.com/en/watch/OxKcmrWVQmc The New Science of Aging: 10 Things to Know Before 2026 Ends https://i.ytimg.com/vi/OxKcmrWVQmc/hqdefault.jpg What’s worth paying attention to in health and wellness right now? In this episode, I break down 10 emerging health strategies and areas of research that I’m most excited about, from hormones and metabolism to gut health, sleep, brain health, and longevity. I share the new ideas that could change how we approach healthy aging and the practical takeaways you can start thinking about now. Get ready to discover what’s next in health and the science that could help you feel stronger, sharper, and healthier for years to come. Check out our Sponsors: Air Doctor - Head to https://airdoctorpro.com and use promo code AMY to get $300 off ANY of their select AirDoctor models, plus you will get a 3-year warranty, absolutely FREE! Quince - Download the Quince app for app-exclusive offers, or go to https://quince.com/drshah. Get free shipping on your order and 365-day returns. In this episode, you will learn: 00:00 The 10 emerging health strategies I’m most excited about this year. 03:30 How could precision medicine change hormone therapy for women? 07:00 Why combining Zone 2 and sprint training may improve metabolic health. 10:30 How your gut microbiome influences hormones, mood, and longevity. 12:15 Why circadian rhythms and temperature matter for better sleep. 15:30 How vagus nerve stimulation could support stress regulation. 16:45 Could GLP-1s have benefits beyond weight loss? 18:45 How leucine can support muscle building as you age. 19:45 What does the latest research say about creatine for brain health? 21:15 How to support mitochondrial health for energy and longevity. 22:45 Why heavy lifting matters for stronger bones. 25:45 The health strategy I’d prioritize first from this list. Resources Get your copy of my book Hormone Havoc HERE https://amymdwellness.com/book/hormone-havoc/ Get your FREE Guide to “The Basics” HERE - 6 things you should be doing for your health! https://stan.store/fastingmd?fbclid=PAZXh0bgNhZW0CMTEAAaf89Fg17WSlno5zWVmPuytSWJN8VnBLE63RGWzYDM14dMjjLiTS1UdI8lH79A_aem_l0cltJdA6VkR-9t5tU https://www.youtube-nocookie.com/embed/OxKcmrWVQmc 1686 2026-08-17T08:30:06.000Z 2026-10-22T19:43:45.284Z https://longevityharbor.com/de/watch/OxKcmrWVQmc The New Science of Aging: 10 Things to Know Before 2026 Ends https://i.ytimg.com/vi/OxKcmrWVQmc/hqdefault.jpg What’s worth paying attention to in health and wellness right now? In this episode, I break down 10 emerging health strategies and areas of research that I’m most excited about, from hormones and metabolism to gut health, sleep, brain health, and longevity. I share the new ideas that could change how we approach healthy aging and the practical takeaways you can start thinking about now. Get ready to discover what’s next in health and the science that could help you feel stronger, sharper, and healthier for years to come. Check out our Sponsors: Air Doctor - Head to https://airdoctorpro.com and use promo code AMY to get $300 off ANY of their select AirDoctor models, plus you will get a 3-year warranty, absolutely FREE! Quince - Download the Quince app for app-exclusive offers, or go to https://quince.com/drshah. Get free shipping on your order and 365-day returns. In this episode, you will learn: 00:00 The 10 emerging health strategies I’m most excited about this year. 03:30 How could precision medicine change hormone therapy for women? 07:00 Why combining Zone 2 and sprint training may improve metabolic health. 10:30 How your gut microbiome influences hormones, mood, and longevity. 12:15 Why circadian rhythms and temperature matter for better sleep. 15:30 How vagus nerve stimulation could support stress regulation. 16:45 Could GLP-1s have benefits beyond weight loss? 18:45 How leucine can support muscle building as you age. 19:45 What does the latest research say about creatine for brain health? 21:15 How to support mitochondrial health for energy and longevity. 22:45 Why heavy lifting matters for stronger bones. 25:45 The health strategy I’d prioritize first from this list. Resources Get your copy of my book Hormone Havoc HERE https://amymdwellness.com/book/hormone-havoc/ Get your FREE Guide to “The Basics” HERE - 6 things you should be doing for your health! https://stan.store/fastingmd?fbclid=PAZXh0bgNhZW0CMTEAAaf89Fg17WSlno5zWVmPuytSWJN8VnBLE63RGWzYDM14dMjjLiTS1UdI8lH79A_aem_l0cltJdA6VkR-9t5tU https://www.youtube-nocookie.com/embed/OxKcmrWVQmc 1686 2026-08-17T08:30:06.000Z 2026-10-22T19:43:45.284Z https://longevityharbor.com/en/watch/P-rIOJeqJKA 𝗨𝗻𝗹𝗼𝗰𝗸𝗶𝗻𝗴 𝘁𝗵𝗲 𝗦𝗲𝗰𝗿𝗲𝘁𝘀 𝗼𝗳 𝗘𝗽𝗶𝗴𝗲𝗻𝗲𝘁𝗶𝗰𝘀 𝗳𝗼𝗿 𝗛𝗲𝗮𝗹𝘁𝗵𝘆 𝗔𝗴𝗶𝗻 https://i.ytimg.com/vi/P-rIOJeqJKA/hqdefault.jpg How diet impacts our genetics and epigenetics, highlighting the importance of whole foods over processed options. Discover how your choices can influence not only your health but also future generations! #DrDeniseFurness #YourGenesandNutrition #Epigenetics #HealthyAging #NutritionMatters #WholeFoods #DNAHealth #AntiInflammatory #FutureGenerations #Methylation #DietaryChoices #BioactiveCompounds https://www.youtube-nocookie.com/embed/P-rIOJeqJKA 166 2025-01-29T05:27:08.000Z 2026-10-22T18:54:03.122Z https://longevityharbor.com/de/watch/P-rIOJeqJKA 𝗨𝗻𝗹𝗼𝗰𝗸𝗶𝗻𝗴 𝘁𝗵𝗲 𝗦𝗲𝗰𝗿𝗲𝘁𝘀 𝗼𝗳 𝗘𝗽𝗶𝗴𝗲𝗻𝗲𝘁𝗶𝗰𝘀 𝗳𝗼𝗿 𝗛𝗲𝗮𝗹𝘁𝗵𝘆 𝗔𝗴𝗶𝗻 https://i.ytimg.com/vi/P-rIOJeqJKA/hqdefault.jpg How diet impacts our genetics and epigenetics, highlighting the importance of whole foods over processed options. Discover how your choices can influence not only your health but also future generations! #DrDeniseFurness #YourGenesandNutrition #Epigenetics #HealthyAging #NutritionMatters #WholeFoods #DNAHealth #AntiInflammatory #FutureGenerations #Methylation #DietaryChoices #BioactiveCompounds https://www.youtube-nocookie.com/embed/P-rIOJeqJKA 166 2025-01-29T05:27:08.000Z 2026-10-22T18:54:03.122Z https://longevityharbor.com/en/watch/P1M17neFkaQ Optimizing Stem Cell Health and Longevity: A Deep Dive with Dr. Dan Pardi https://i.ytimg.com/vi/P1M17neFkaQ/hqdefault.jpg This video is for educational purposes only and does not provide medical advice, diagnosis, or treatment. Do not start, stop, or change any medication, peptide, or supplement based on this video. All medical decisions must be made with a licensed prescribing clinician after a proper evaluation. No provider–patient relationship is created by viewing this content or contacting our clinic. Our licensed medical team uses these tools as part of comprehensive evaluations. This is not a direct ordering service for viewers of this video. Regan Archibald is a Licensed Acupuncturist and longevity coach. Cade Archibald is the Co-Founder of Ageless Future. They are not medical doctors. All medical decisions, lab ordering, and prescribing in our clinic are performed only by our licensed medical team (MD, APRN, PA). In this episode of Ageless Future, Cade Archibald sits down with Dr. Dan Pardi—Chief Health Officer at Qualia Life Sciences and founder of HumanOS—to explore cutting-edge strategies for extending healthspan through stem cell optimization, senolytics, and targeted nutraceuticals. Dr. Pardi breaks down the science behind stem cell exhaustion, the hallmarks of aging, and how Qualia’s stem cell product was formulated with 15 research-backed compounds to support regeneration, tissue repair, and long-term vitality. They discuss clinical trials showing rapid improvements in energy, joint function, and clarity, and how combining stem cell support with NAD boosters and senolytics creates a synergistic protocol for reversing aging at the cellular level. Dr. Dan Pardi is the Chief Health Officer at Qualia Life Sciences, where he leads education to advance healthspan and peak performance. He’s the founder of humanOS.me and host of humanOS Radio, the official podcast of the Sleep Research Society. Dan has advised elite military units, Fortune 500 companies, and startups through his consultancy, Vivendi Health. He holds a PhD in Cognitive Neuroscience from Leiden University and Stanford, and speaks regularly at eve https://www.youtube-nocookie.com/embed/P1M17neFkaQ 3126 2025-11-26T18:35:28.000Z 2026-10-22T19:04:37.632Z https://longevityharbor.com/de/watch/P1M17neFkaQ Optimizing Stem Cell Health and Longevity: A Deep Dive with Dr. Dan Pardi https://i.ytimg.com/vi/P1M17neFkaQ/hqdefault.jpg This video is for educational purposes only and does not provide medical advice, diagnosis, or treatment. Do not start, stop, or change any medication, peptide, or supplement based on this video. All medical decisions must be made with a licensed prescribing clinician after a proper evaluation. No provider–patient relationship is created by viewing this content or contacting our clinic. Our licensed medical team uses these tools as part of comprehensive evaluations. This is not a direct ordering service for viewers of this video. Regan Archibald is a Licensed Acupuncturist and longevity coach. Cade Archibald is the Co-Founder of Ageless Future. They are not medical doctors. All medical decisions, lab ordering, and prescribing in our clinic are performed only by our licensed medical team (MD, APRN, PA). In this episode of Ageless Future, Cade Archibald sits down with Dr. Dan Pardi—Chief Health Officer at Qualia Life Sciences and founder of HumanOS—to explore cutting-edge strategies for extending healthspan through stem cell optimization, senolytics, and targeted nutraceuticals. Dr. Pardi breaks down the science behind stem cell exhaustion, the hallmarks of aging, and how Qualia’s stem cell product was formulated with 15 research-backed compounds to support regeneration, tissue repair, and long-term vitality. They discuss clinical trials showing rapid improvements in energy, joint function, and clarity, and how combining stem cell support with NAD boosters and senolytics creates a synergistic protocol for reversing aging at the cellular level. Dr. Dan Pardi is the Chief Health Officer at Qualia Life Sciences, where he leads education to advance healthspan and peak performance. He’s the founder of humanOS.me and host of humanOS Radio, the official podcast of the Sleep Research Society. Dan has advised elite military units, Fortune 500 companies, and startups through his consultancy, Vivendi Health. He holds a PhD in Cognitive Neuroscience from Leiden University and Stanford, and speaks regularly at eve https://www.youtube-nocookie.com/embed/P1M17neFkaQ 3126 2025-11-26T18:35:28.000Z 2026-10-22T19:04:37.632Z https://longevityharbor.com/en/watch/P3QAhDWv7N8 Is Fasting the Secret to Slow Aging After Cancer? Longevity Expert Dr. Valter Longo Weighs In https://i.ytimg.com/vi/P3QAhDWv7N8/hqdefault.jpg S4E14 Many breast cancer survivors notice something unsettling after treatment ends: their body feels older. Energy shifts. Skin changes. Recovery feels slower. In this episode, we sit down with Dr. Valter Longo, a world-renowned longevity researcher, to explore whether cancer treatment accelerates aging — and what science says can actually help support healing and long-term health. This is a grounded, evidence-based conversation about nutrition, aging, and the body’s ability to repair itself. We discuss the Longevity Diet, protein intake, sugar, fasting, and the science behind the fasting mimicking diet — with special attention to cancer patients and survivors. This episode is not about extremes or quick fixes. It’s about understanding your body, protecting your future health, and making informed choices with compassion and clarity. In This Episode, We Discuss: • Whether cancer treatment accelerates aging • How nutrition impacts longevity and cellular repair • The Longevity Diet and age-specific protein needs • Sugar, inflammation, and aging after cancer • The science behind the fasting mimicking diet • What survivors should know before trying fasting approaches About Besties with Breasties & Faith Through Fire Faith Through Fire is a 501c3 Non-Profit. Our mission is to reduce the fear and anxiety that breast cancer patients feel and replace it with hope and a path toward thriving. We do this through peer mentorship, which can be implemented nationwide. We host educational supports in-person and virtually to help overcome the trauma of breast cancer. Learn more or become a supporter at faiththroughfire.org Subscribe for more episodes and survivor stories. Connect with us on social media: Facebook: https://www.facebook.com/FaithroughFire/ Instagram: https://www.instagram.com/faithroughfire/ If you’ve been wondering why your body feels different after cancer, we hope this conversation helps you feel informed and encouraged. https://www.youtube-nocookie.com/embed/P3QAhDWv7N8 2089 2024-02-06T21:24:55.000Z 2026-10-22T19:54:18.024Z https://longevityharbor.com/de/watch/P3QAhDWv7N8 Is Fasting the Secret to Slow Aging After Cancer? Longevity Expert Dr. Valter Longo Weighs In https://i.ytimg.com/vi/P3QAhDWv7N8/hqdefault.jpg S4E14 Many breast cancer survivors notice something unsettling after treatment ends: their body feels older. Energy shifts. Skin changes. Recovery feels slower. In this episode, we sit down with Dr. Valter Longo, a world-renowned longevity researcher, to explore whether cancer treatment accelerates aging — and what science says can actually help support healing and long-term health. This is a grounded, evidence-based conversation about nutrition, aging, and the body’s ability to repair itself. We discuss the Longevity Diet, protein intake, sugar, fasting, and the science behind the fasting mimicking diet — with special attention to cancer patients and survivors. This episode is not about extremes or quick fixes. It’s about understanding your body, protecting your future health, and making informed choices with compassion and clarity. In This Episode, We Discuss: • Whether cancer treatment accelerates aging • How nutrition impacts longevity and cellular repair • The Longevity Diet and age-specific protein needs • Sugar, inflammation, and aging after cancer • The science behind the fasting mimicking diet • What survivors should know before trying fasting approaches About Besties with Breasties & Faith Through Fire Faith Through Fire is a 501c3 Non-Profit. Our mission is to reduce the fear and anxiety that breast cancer patients feel and replace it with hope and a path toward thriving. We do this through peer mentorship, which can be implemented nationwide. We host educational supports in-person and virtually to help overcome the trauma of breast cancer. Learn more or become a supporter at faiththroughfire.org Subscribe for more episodes and survivor stories. Connect with us on social media: Facebook: https://www.facebook.com/FaithroughFire/ Instagram: https://www.instagram.com/faithroughfire/ If you’ve been wondering why your body feels different after cancer, we hope this conversation helps you feel informed and encouraged. https://www.youtube-nocookie.com/embed/P3QAhDWv7N8 2089 2024-02-06T21:24:55.000Z 2026-10-22T19:54:18.024Z https://longevityharbor.com/en/watch/P3SDpWQ5MbE Steve Horvath on Epigenetics, Aging, and Reversing the Biological Clock | WIRED Health https://i.ytimg.com/vi/P3SDpWQ5MbE/hqdefault.jpg At WIRED Health 2025, Steve Horvath, Principal Investigator at Altos Labs, offered a fascinating dive into how epigenetics could change the future of ageing and rejuvenation. Known for developing the Horvath Clock, a tool that measures biological age through DNA methylation, Steve explained why our biological age (how our cells are really ageing) is far more telling than chronological age (the number of years we’ve lived). Steve’s work at Altos Labs is pioneering efforts to not just slow down aging but to reverse it. By understanding the biological processes at play, he and his team are investigating ways to rejuvenate cells and restore them to a healthier state—potentially erasing years of damage caused by age and disease. Fun fact: Steve first once tested his own GrimAge clock and discovered his biological age was five years older than his chronological age. This prompted him to adopt lifestyle changes to improve his health. Key insights from the session: - The science behind the Horvath Clock and how it measures true biological age - Why distinguishing between chronological and biological age is crucial to understanding aging - What cellular reprogramming and epigenetic rejuvenation could mean for the future of longevity - The connection between epigenetics and age-related conditions like dementia, heart disease, and cancer - The potential impact of lifestyle and environmental factors on biological age, and whether we can reverse these effects Steve also tackled some tough questions, discussing the challenges of rejuvenating human cells, the ethics around longevity, and how the science might eventually make its way into clinical treatments. ABOUT WIRED WIRED brings you the future as it happens - the people, the trends, the big ideas that will change our lives. An award-winning printed monthly and online publication. WIRED is an agenda-setting magazine offering brain food on a wide range of topics, from science, technology and business to pop-culture and politics. CONNECT WITH WIRED 🎟️ Events: wired.uk/e https://www.youtube-nocookie.com/embed/P3SDpWQ5MbE 877 2025-03-25T12:48:09.000Z 2026-10-22T18:32:06.765Z https://longevityharbor.com/de/watch/P3SDpWQ5MbE Steve Horvath on Epigenetics, Aging, and Reversing the Biological Clock | WIRED Health https://i.ytimg.com/vi/P3SDpWQ5MbE/hqdefault.jpg At WIRED Health 2025, Steve Horvath, Principal Investigator at Altos Labs, offered a fascinating dive into how epigenetics could change the future of ageing and rejuvenation. Known for developing the Horvath Clock, a tool that measures biological age through DNA methylation, Steve explained why our biological age (how our cells are really ageing) is far more telling than chronological age (the number of years we’ve lived). Steve’s work at Altos Labs is pioneering efforts to not just slow down aging but to reverse it. By understanding the biological processes at play, he and his team are investigating ways to rejuvenate cells and restore them to a healthier state—potentially erasing years of damage caused by age and disease. Fun fact: Steve first once tested his own GrimAge clock and discovered his biological age was five years older than his chronological age. This prompted him to adopt lifestyle changes to improve his health. Key insights from the session: - The science behind the Horvath Clock and how it measures true biological age - Why distinguishing between chronological and biological age is crucial to understanding aging - What cellular reprogramming and epigenetic rejuvenation could mean for the future of longevity - The connection between epigenetics and age-related conditions like dementia, heart disease, and cancer - The potential impact of lifestyle and environmental factors on biological age, and whether we can reverse these effects Steve also tackled some tough questions, discussing the challenges of rejuvenating human cells, the ethics around longevity, and how the science might eventually make its way into clinical treatments. ABOUT WIRED WIRED brings you the future as it happens - the people, the trends, the big ideas that will change our lives. An award-winning printed monthly and online publication. WIRED is an agenda-setting magazine offering brain food on a wide range of topics, from science, technology and business to pop-culture and politics. CONNECT WITH WIRED 🎟️ Events: wired.uk/e https://www.youtube-nocookie.com/embed/P3SDpWQ5MbE 877 2025-03-25T12:48:09.000Z 2026-10-22T18:32:06.765Z https://longevityharbor.com/en/watch/P5053hkoXU8 Dr. David Barzilai: Can We Reverse Aging? Harvard's Latest Longevity Science Explained https://i.ytimg.com/vi/P5053hkoXU8/hqdefault.jpg Is the aging process something we can actually control, or are we simply waiting for the inevitable? In this episode, Dr. Darshan Shah sits down with Dr. David Barzilai, a Harvard Medical School lecturer and leading authority on precision longevity medicine, to bridge the gap between academic research and actionable health strategies. They dive deep into the "Hallmarks of Aging," the fundamental biological drivers that determine how fast we age and when chronic diseases like Alzheimer’s and heart disease begin to take hold. IN THIS EPISODE: ✔️ The evolution of geroscience from a descriptive study to an applied medical practice. ✔️ Understanding the 12 Hallmarks of Aging and how they drive chronic disease. ✔️ Why some species age faster than others and what humans can learn from them. ✔️ The difference between chronological age and biological age in clinical practice. ✔️ How single gene mutations in animal models have doubled lifespans and what that means for humans. ✔️ Insights from Harvard Medical School’s first special report on longevity and evidence-based best practices. TOP 5 LEARNINGS 1. Fitness dwarfs traditional disease risk factors High cardiorespiratory fitness can increase the probability of survival five-fold, far exceeding the impact of avoiding smoking or managing diabetes in longitudinal studies. 2. Aging is a modifiable biological driver Research in animal models has shown that modifying single genes can double lifespan, proving that aging is a regulated process rather than just random wear and tear. 3. Precision medicine requires a data baseline You cannot optimize what you do not measure; effective longevity protocols must begin with rigorous risk stratification through blood work, genomics, and functional testing to identify individual blind spots. 4. The U-curve of telomere length While short telomeres are a hallmark of aging, excessively long telomeres are associated with an increased risk for certain cancers, highlighting the need for biological balance over simple maximization. 5. Soc https://www.youtube-nocookie.com/embed/P5053hkoXU8 3699 2026-10-20T15:02:17.000Z 2026-10-22T17:43:39.313Z https://longevityharbor.com/de/watch/P5053hkoXU8 Dr. David Barzilai: Can We Reverse Aging? Harvard's Latest Longevity Science Explained https://i.ytimg.com/vi/P5053hkoXU8/hqdefault.jpg Is the aging process something we can actually control, or are we simply waiting for the inevitable? In this episode, Dr. Darshan Shah sits down with Dr. David Barzilai, a Harvard Medical School lecturer and leading authority on precision longevity medicine, to bridge the gap between academic research and actionable health strategies. They dive deep into the "Hallmarks of Aging," the fundamental biological drivers that determine how fast we age and when chronic diseases like Alzheimer’s and heart disease begin to take hold. IN THIS EPISODE: ✔️ The evolution of geroscience from a descriptive study to an applied medical practice. ✔️ Understanding the 12 Hallmarks of Aging and how they drive chronic disease. ✔️ Why some species age faster than others and what humans can learn from them. ✔️ The difference between chronological age and biological age in clinical practice. ✔️ How single gene mutations in animal models have doubled lifespans and what that means for humans. ✔️ Insights from Harvard Medical School’s first special report on longevity and evidence-based best practices. TOP 5 LEARNINGS 1. Fitness dwarfs traditional disease risk factors High cardiorespiratory fitness can increase the probability of survival five-fold, far exceeding the impact of avoiding smoking or managing diabetes in longitudinal studies. 2. Aging is a modifiable biological driver Research in animal models has shown that modifying single genes can double lifespan, proving that aging is a regulated process rather than just random wear and tear. 3. Precision medicine requires a data baseline You cannot optimize what you do not measure; effective longevity protocols must begin with rigorous risk stratification through blood work, genomics, and functional testing to identify individual blind spots. 4. The U-curve of telomere length While short telomeres are a hallmark of aging, excessively long telomeres are associated with an increased risk for certain cancers, highlighting the need for biological balance over simple maximization. 5. Soc https://www.youtube-nocookie.com/embed/P5053hkoXU8 3699 2026-10-20T15:02:17.000Z 2026-10-22T17:43:39.313Z https://longevityharbor.com/en/watch/P59gtMntWLE The Truth About Autophagy, mTOR and Longevity https://i.ytimg.com/vi/P59gtMntWLE/hqdefault.jpg ✅ Subscribe to my Channel: https://www.youtube.com/djockers In this video, I go through how to leverage and cycle between mTOR and autophagy. mTOR is a nutrient sensing pathway in the body that triggers cell growth and increased biomass. Autophagy signals cell repair and cellular resilience. Explore the critical functions of mTOR and autophagy in cellular metabolism and their influence on longevity. Understand how mTOR supports cell growth and the importance of its equilibrium with autophagy, which dismantles damaged proteins. Discover how practices such as fasting, entering ketosis, and consuming polyphenols can suppress mTOR and enhance autophagy. Learn about the effects of exercise, dietary choices, and inflammation on mTOR activities and their overall implications for aging and health. Read More Here: https://drjockers.com/the-truth-about-mtor-autophagy-and-longevity/ ---------------------------------------------------------------------------------------------------------------------------------------- ✅ Listen to my Podcast on Apple, and leave a review! Apple Podcast - https://podcasts.apple.com/us/podcast/dr-jockers-functional-nutrition/id1497791107 ✅ Listen on Spotify: Spotify - https://open.spotify.com/show/5l0LkYqW29ksV9Ut3hPuto IMPORTANT: Some product links are affiliate links which means if you buy something we’ll receive a small commission. AFFILIATE DISCLAIMER: Please see the link for our disclaimer policy for all of our videos on the Dr. Jockers YouTube Channel and Dr. Jockers Functional Nutrition Podcast. Thank you for supporting the channel! -- https://drjockers.com/drjockers-com-affiliate-disclosure/ mtor,autophagy,longevity,Podcasts,metabolism,Dr David Jockers,dr david jockers,jockers,david,health,david jockers,drdavidjockers,The Truth About Autophagy mTOR and Longevity,the truth about autophagy mtor and longevity,truth about autophagy,truth about mtor,truth about longevity,autophagy benefits,the truth about mtor autophagy and longevity https://www.youtube-nocookie.com/embed/P59gtMntWLE 411 2024-09-05T11:00:22.000Z 2026-10-22T19:54:21.293Z https://longevityharbor.com/de/watch/P59gtMntWLE The Truth About Autophagy, mTOR and Longevity https://i.ytimg.com/vi/P59gtMntWLE/hqdefault.jpg ✅ Subscribe to my Channel: https://www.youtube.com/djockers In this video, I go through how to leverage and cycle between mTOR and autophagy. mTOR is a nutrient sensing pathway in the body that triggers cell growth and increased biomass. Autophagy signals cell repair and cellular resilience. Explore the critical functions of mTOR and autophagy in cellular metabolism and their influence on longevity. Understand how mTOR supports cell growth and the importance of its equilibrium with autophagy, which dismantles damaged proteins. Discover how practices such as fasting, entering ketosis, and consuming polyphenols can suppress mTOR and enhance autophagy. Learn about the effects of exercise, dietary choices, and inflammation on mTOR activities and their overall implications for aging and health. Read More Here: https://drjockers.com/the-truth-about-mtor-autophagy-and-longevity/ ---------------------------------------------------------------------------------------------------------------------------------------- ✅ Listen to my Podcast on Apple, and leave a review! Apple Podcast - https://podcasts.apple.com/us/podcast/dr-jockers-functional-nutrition/id1497791107 ✅ Listen on Spotify: Spotify - https://open.spotify.com/show/5l0LkYqW29ksV9Ut3hPuto IMPORTANT: Some product links are affiliate links which means if you buy something we’ll receive a small commission. AFFILIATE DISCLAIMER: Please see the link for our disclaimer policy for all of our videos on the Dr. Jockers YouTube Channel and Dr. Jockers Functional Nutrition Podcast. Thank you for supporting the channel! -- https://drjockers.com/drjockers-com-affiliate-disclosure/ mtor,autophagy,longevity,Podcasts,metabolism,Dr David Jockers,dr david jockers,jockers,david,health,david jockers,drdavidjockers,The Truth About Autophagy mTOR and Longevity,the truth about autophagy mtor and longevity,truth about autophagy,truth about mtor,truth about longevity,autophagy benefits,the truth about mtor autophagy and longevity https://www.youtube-nocookie.com/embed/P59gtMntWLE 411 2024-09-05T11:00:22.000Z 2026-10-22T19:54:21.293Z https://longevityharbor.com/en/watch/PAEx-5CdX94 Aging Expert Explains How Healthcare got it ALL WRONG. | 28 - HSM #6 https://i.ytimg.com/vi/PAEx-5CdX94/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Related episodes: https://youtu.be/YhzgYaY7wto In April 2024, Matt delivered a presentation at a two-day congressional briefing on longevity science hosted at Washington, D.C.'s Mayflower Hotel by the Alliance for Longevity Initiatives (A4LI). Attendees included former Speaker of the House Newt Gingrich, Republican Congressman Gus Bilirakis, and Democratic Congressman Paul Tonko. We have decided to include Matt's presentation on our channel because we believe it delivers a valuable message. Healthcare has historically taken a piecemeal approach to diseases, addressing ailments in isolation. While this method has been successful at curing and sometimes even eradicating multiple diseases, it has its limitations. Aging is the single greatest risk factor for many of the chronic diseases we worry about in later life—think cancer, Alzheimer's disease, diabetes—and involves a complex interplay of molecular, cellular, and physiological changes that underlie a myriad of health conditions. There is a reason that your average 80-year-old has more health problems than your average 18-year-old. As our understanding of human biology deepens, it is becoming increasingly evident that we need to broaden our focus beyond individual diseases and incorporate the biology of aging into strategies for improving human health and resilience to disease. Achieving this paradigm shift towards addressing the fundamental processes of aging, which will require interdisciplinary collaboration between scientists, clinicians, policymakers, and the public, will give us the potential to mitigate multiple age-related diseases simultaneously. In this episode, Matt covers how we got here, the differences between 19th and 21st century medicine, and the importance of targeting the biological aging process to create transformative results in tackling healthcare challenges. He also discusses policy reforms that would be useful for the cause, including changes to FDA regulation, a rethinking o https://www.youtube-nocookie.com/embed/PAEx-5CdX94 1722 2024-04-30T14:00:24.000Z 2026-10-22T18:32:11.688Z https://longevityharbor.com/de/watch/PAEx-5CdX94 Aging Expert Explains How Healthcare got it ALL WRONG. | 28 - HSM #6 https://i.ytimg.com/vi/PAEx-5CdX94/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Related episodes: https://youtu.be/YhzgYaY7wto In April 2024, Matt delivered a presentation at a two-day congressional briefing on longevity science hosted at Washington, D.C.'s Mayflower Hotel by the Alliance for Longevity Initiatives (A4LI). Attendees included former Speaker of the House Newt Gingrich, Republican Congressman Gus Bilirakis, and Democratic Congressman Paul Tonko. We have decided to include Matt's presentation on our channel because we believe it delivers a valuable message. Healthcare has historically taken a piecemeal approach to diseases, addressing ailments in isolation. While this method has been successful at curing and sometimes even eradicating multiple diseases, it has its limitations. Aging is the single greatest risk factor for many of the chronic diseases we worry about in later life—think cancer, Alzheimer's disease, diabetes—and involves a complex interplay of molecular, cellular, and physiological changes that underlie a myriad of health conditions. There is a reason that your average 80-year-old has more health problems than your average 18-year-old. As our understanding of human biology deepens, it is becoming increasingly evident that we need to broaden our focus beyond individual diseases and incorporate the biology of aging into strategies for improving human health and resilience to disease. Achieving this paradigm shift towards addressing the fundamental processes of aging, which will require interdisciplinary collaboration between scientists, clinicians, policymakers, and the public, will give us the potential to mitigate multiple age-related diseases simultaneously. In this episode, Matt covers how we got here, the differences between 19th and 21st century medicine, and the importance of targeting the biological aging process to create transformative results in tackling healthcare challenges. He also discusses policy reforms that would be useful for the cause, including changes to FDA regulation, a rethinking o https://www.youtube-nocookie.com/embed/PAEx-5CdX94 1722 2024-04-30T14:00:24.000Z 2026-10-22T18:32:11.688Z https://longevityharbor.com/en/watch/PBKdIkBmKwU NAD+, NMN and Longevity: What Human Studies Actually Show | Dr Rupy Aujla | Be Well Moments https://i.ytimg.com/vi/PBKdIkBmKwU/hqdefault.jpg 👉 Practical beats perfect. Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks. https://sarahannmacklin.com/5_free_recipes 👉 If this resonates, you can join the thousands who read The Compassionate Cure each week. https://sarahmacklin.substack.com/ Watch the FULL podcast here: https://youtu.be/AySFUeR1pw8 Are NAD+ drips or NMN supplements a smart way to support longevity? I connect what NAD+ actually is with what current human studies show and why dosage, delivery and safety still have big question marks. This clip takes a closer look at what NAD+ (nicotinamide adenine dinucleotide) does in cellular energy, why interest has grown around aging, and how much of the hype is based on animal data rather than robust human trials. I’m exploring with my guest the difference between oral supplements and IV drips, including why IV bypasses digestion but still may not deliver NAD+ where it’s needed inside cells, and the fact that effective dosing schedules are unknown. We discuss reported side effects from IV drips like flushing and rapid heart rate, the theoretical concern that excessive NAD+ could support cancer cell proliferation in certain contexts, and how high-dose single nutrients can disrupt balance when nutrients normally work in synergy. As a nutritionist and health communicator, I weigh the evidence against the costs and risks, and point to practical options with stronger support for mitochondrial health: exercise such as HIIT and zone 2 training, possibly cold exposure, investing in mental health, and dietary precursors from foods like green vegetables, fish, mushrooms and edamame. *** This episode is sponsored by: NOWATCH: Health tracking reimagined Know your body, trust yourself. 15% off with code LWBW15 at nowatch.com *** The Great British Veg Out How to support your gut, energy, and hormones by eating more — not less. 👉 sarahannmacklin.com/vegout Reset Your Health If your body feels off after stress, travel, or burnout — this is where to start. 👉 sarahannmacklin.co https://www.youtube-nocookie.com/embed/PBKdIkBmKwU 645 2025-10-13T13:00:54.000Z 2026-10-22T19:04:43.104Z https://longevityharbor.com/de/watch/PBKdIkBmKwU NAD+, NMN and Longevity: What Human Studies Actually Show | Dr Rupy Aujla | Be Well Moments https://i.ytimg.com/vi/PBKdIkBmKwU/hqdefault.jpg 👉 Practical beats perfect. Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks. https://sarahannmacklin.com/5_free_recipes 👉 If this resonates, you can join the thousands who read The Compassionate Cure each week. https://sarahmacklin.substack.com/ Watch the FULL podcast here: https://youtu.be/AySFUeR1pw8 Are NAD+ drips or NMN supplements a smart way to support longevity? I connect what NAD+ actually is with what current human studies show and why dosage, delivery and safety still have big question marks. This clip takes a closer look at what NAD+ (nicotinamide adenine dinucleotide) does in cellular energy, why interest has grown around aging, and how much of the hype is based on animal data rather than robust human trials. I’m exploring with my guest the difference between oral supplements and IV drips, including why IV bypasses digestion but still may not deliver NAD+ where it’s needed inside cells, and the fact that effective dosing schedules are unknown. We discuss reported side effects from IV drips like flushing and rapid heart rate, the theoretical concern that excessive NAD+ could support cancer cell proliferation in certain contexts, and how high-dose single nutrients can disrupt balance when nutrients normally work in synergy. As a nutritionist and health communicator, I weigh the evidence against the costs and risks, and point to practical options with stronger support for mitochondrial health: exercise such as HIIT and zone 2 training, possibly cold exposure, investing in mental health, and dietary precursors from foods like green vegetables, fish, mushrooms and edamame. *** This episode is sponsored by: NOWATCH: Health tracking reimagined Know your body, trust yourself. 15% off with code LWBW15 at nowatch.com *** The Great British Veg Out How to support your gut, energy, and hormones by eating more — not less. 👉 sarahannmacklin.com/vegout Reset Your Health If your body feels off after stress, travel, or burnout — this is where to start. 👉 sarahannmacklin.co https://www.youtube-nocookie.com/embed/PBKdIkBmKwU 645 2025-10-13T13:00:54.000Z 2026-10-22T19:04:43.104Z https://longevityharbor.com/en/watch/PDTsALC9FaY The One “Drug” That Outperforms Them All: Exercise and Aging Explained (w/ Ben Miller, Ph.D., OMRF) https://i.ytimg.com/vi/PDTsALC9FaY/hqdefault.jpg We all know movement is good for us. But can the right kind of exercise actually slow the aging process itself? In this episode, Dr. Kevin White talks with Benjamin Miller, Ph.D., professor of aging research at OMRF and past president of the American Aging Association, about what really happens to our muscles and mitochondria as we age, and how his new NIH-funded clinical trial is working to answer one of the most important questions in longevity science: why do some people respond to exercise better than others? "Every drug we study is just trying to be as good as exercise — and exercise still wins." Dr. Miller explains the biology of aging in plain language, from protein damage to energy production, and shares why exercise still outperforms any “miracle drug” on the market. He also unpacks the design of his new trial, where people 60 and older will receive supervised training, advanced health testing, and wearables to measure everything from VO₂ max to sleep — all with the goal of predicting who benefits most from which type of exercise. In this episode: Why exercise is still the closest thing we have to a longevity drug How mitochondria and protein health drive resilience as we age What VO₂ max actually measures — and why it predicts lifespan The role of genetics vs. lifestyle in how our bodies respond to training How to get involved in Dr. Miller’s NIH-backed exercise study at OMRF This conversation is a reminder that slowing aging isn’t about hacks or shortcuts — it’s about moving, staying engaged, and using science to make every decade stronger than the last. https://www.youtube-nocookie.com/embed/PDTsALC9FaY 3367 2025-10-31T17:33:31.000Z 2026-10-22T19:32:34.436Z https://longevityharbor.com/de/watch/PDTsALC9FaY The One “Drug” That Outperforms Them All: Exercise and Aging Explained (w/ Ben Miller, Ph.D., OMRF) https://i.ytimg.com/vi/PDTsALC9FaY/hqdefault.jpg We all know movement is good for us. But can the right kind of exercise actually slow the aging process itself? In this episode, Dr. Kevin White talks with Benjamin Miller, Ph.D., professor of aging research at OMRF and past president of the American Aging Association, about what really happens to our muscles and mitochondria as we age, and how his new NIH-funded clinical trial is working to answer one of the most important questions in longevity science: why do some people respond to exercise better than others? "Every drug we study is just trying to be as good as exercise — and exercise still wins." Dr. Miller explains the biology of aging in plain language, from protein damage to energy production, and shares why exercise still outperforms any “miracle drug” on the market. He also unpacks the design of his new trial, where people 60 and older will receive supervised training, advanced health testing, and wearables to measure everything from VO₂ max to sleep — all with the goal of predicting who benefits most from which type of exercise. In this episode: Why exercise is still the closest thing we have to a longevity drug How mitochondria and protein health drive resilience as we age What VO₂ max actually measures — and why it predicts lifespan The role of genetics vs. lifestyle in how our bodies respond to training How to get involved in Dr. Miller’s NIH-backed exercise study at OMRF This conversation is a reminder that slowing aging isn’t about hacks or shortcuts — it’s about moving, staying engaged, and using science to make every decade stronger than the last. https://www.youtube-nocookie.com/embed/PDTsALC9FaY 3367 2025-10-31T17:33:31.000Z 2026-10-22T19:32:34.436Z https://longevityharbor.com/en/watch/PFKuxj5T6GA Matt Kaeberlein on Rapamycin Longevity Series | Lessons learned from 2 decades of Rapamycin research https://i.ytimg.com/vi/PFKuxj5T6GA/hqdefault.jpg Professor Matt Kaeberlein from the University of Washington is one of the world's leading researchers in the Rapamycin field. He has done Rapamycin research on multiple species for two decades. Everything from yeasts, worms, mice and now also dogs and humans. Matt has made a big contribution to the longevity field and in this podcast he will share the knowledge he has acquired in the field. 00:00 Intro 01:30 How Matt's Rapamycin research started 05:40 First study which showed Rapamycin extends lifespan 07:14 mTOR genetic mutations in humans 09:26 mTOR genetic variants in long-lived humans 10:25 Laron syndrome and effects on mTOR 12:28 Why does mTOR inhibition works so well 13:02 mTOR have two parts mTORC1 and mTORC2 15:18 Rapamycin extends lifespan in multiple species 17:54 Rapamycin effects on the hallmarks of aging 22:52 First Rapamycin ITP study in mice 23:24 ITP study lead to a longevity paradigm shift 33:21 Rapamycin aging effects on mice 37:48 What is Rapamycin 38:30 Rapamycin is a immunomodulator 41:36 Rapamycin improves immune function 50:24 How aging impacts the immune system 55:17 The dog aging project 1:01:08 Effects on time restricted eating on dogs 1:10:19 Rapamycin trial on dogs 1:14:45 Rapamycin trial dose regime in dogs 1:16:57 Rapamycin safety trial results in dogs 1:19:37 Prediction of best Rapamycin effect in humans 1:22:56 Rapamycin human survey study 1:31:58 Longevity interventions and side effects 1:37:35 Biomarkers and measurements 1:41:59 Matt's Rapamycin usage 1:44:14 Optimal dose regime of Rapamycin 1:44:39 Matt's beneficial effects with Rapamycin 1:46:12 Side effects Matt has experienced 1:47:17 Matt's risk and benefit calculation 1:51:22 Matt's view on self-experimentation 1:55:43 The three most promising longevity interventions 1:57:57 Other longevity interventions like NAD, Metformin, Spermidine and AKG 2:02:27 Combination of longevity interventions 2:10:14 Do high doses cross the blood-brain barrier? 2:12:39 Weak points regarding Rapamycin 2:16:05 Rapamycin research is underfunde https://www.youtube-nocookie.com/embed/PFKuxj5T6GA 8939 2023-05-15T00:30:07.000Z 2026-10-22T17:43:41.799Z https://longevityharbor.com/de/watch/PFKuxj5T6GA Matt Kaeberlein on Rapamycin Longevity Series | Lessons learned from 2 decades of Rapamycin research https://i.ytimg.com/vi/PFKuxj5T6GA/hqdefault.jpg Professor Matt Kaeberlein from the University of Washington is one of the world's leading researchers in the Rapamycin field. He has done Rapamycin research on multiple species for two decades. Everything from yeasts, worms, mice and now also dogs and humans. Matt has made a big contribution to the longevity field and in this podcast he will share the knowledge he has acquired in the field. 00:00 Intro 01:30 How Matt's Rapamycin research started 05:40 First study which showed Rapamycin extends lifespan 07:14 mTOR genetic mutations in humans 09:26 mTOR genetic variants in long-lived humans 10:25 Laron syndrome and effects on mTOR 12:28 Why does mTOR inhibition works so well 13:02 mTOR have two parts mTORC1 and mTORC2 15:18 Rapamycin extends lifespan in multiple species 17:54 Rapamycin effects on the hallmarks of aging 22:52 First Rapamycin ITP study in mice 23:24 ITP study lead to a longevity paradigm shift 33:21 Rapamycin aging effects on mice 37:48 What is Rapamycin 38:30 Rapamycin is a immunomodulator 41:36 Rapamycin improves immune function 50:24 How aging impacts the immune system 55:17 The dog aging project 1:01:08 Effects on time restricted eating on dogs 1:10:19 Rapamycin trial on dogs 1:14:45 Rapamycin trial dose regime in dogs 1:16:57 Rapamycin safety trial results in dogs 1:19:37 Prediction of best Rapamycin effect in humans 1:22:56 Rapamycin human survey study 1:31:58 Longevity interventions and side effects 1:37:35 Biomarkers and measurements 1:41:59 Matt's Rapamycin usage 1:44:14 Optimal dose regime of Rapamycin 1:44:39 Matt's beneficial effects with Rapamycin 1:46:12 Side effects Matt has experienced 1:47:17 Matt's risk and benefit calculation 1:51:22 Matt's view on self-experimentation 1:55:43 The three most promising longevity interventions 1:57:57 Other longevity interventions like NAD, Metformin, Spermidine and AKG 2:02:27 Combination of longevity interventions 2:10:14 Do high doses cross the blood-brain barrier? 2:12:39 Weak points regarding Rapamycin 2:16:05 Rapamycin research is underfunde https://www.youtube-nocookie.com/embed/PFKuxj5T6GA 8939 2023-05-15T00:30:07.000Z 2026-10-22T17:43:41.799Z https://longevityharbor.com/en/watch/PHV_VI1SKCg Healthy Aging Diet, Supplements & Gadgets My Parents Use In Their 80s | Rebuilding Mum & Dad https://i.ytimg.com/vi/PHV_VI1SKCg/hqdefault.jpg In this episode of Rebuilding Mum & Dad, I take you inside my parents’ daily routine. You'll find the supplements and tools discussed here https://shopmy.us/shop/collections/408665 In this video you’ll discover: What my mum and dad eat each day (and why they’ve stuck to a Mediterranean-style diet) The supplements they feel help with energy, immunity, and joint health – including NMN Simple lifestyle tools they use, from red light therapy to a home climber My mum’s pared-back skincare routine in her 80s Article summarizing their regimen https://www.honest.scot/health-fitness/mum-dads-healthy-aging-regimen-in-their-80s/ Mum’s skincare routine https://shopmy.us/collections/2114168 👉 More related content: Science behind their regimen https://www.honest.scot/health-fitness/anti-aging-supplements-what-a-shock-multivitamin-study-tells-us/ Natural hair loss solutions we’ve tried https://www.honest.scot/skincare/hair-care/the-best-natural-solution-for-thinning-hair/ More about NMN and why we take it https://youtu.be/BP_IJ3sbKQc My Parents' Strength Training Regimen Explained: https://www.honest.scot/health-fitness/rebuilding-mum-dad-our-strength-training-regimen/ 👉 Rebuilding Mum & Dad playlist: https://www.youtube.com/playlist?list=PLwJwOmOzK8TBO3RfJC4LXOvzShe2ALNds The Honest Channel is hosted by me, Clare Johnston, a journalist in my 50s dedicated to exploring skincare and healthy aging. Here's how you can access more from me: 🤝 Join The Honest Channel and gain access to member posts and perks https://www.youtube.com/channel/UC4qU47VfUwFLDzolJEczYCA/join ✅ Subscribe for more episodes https://www.youtube.com/thehonestchannel 📖 Keep up with my articles on skincare and healthy aging http://www.honest.scot 🚨 Receive my monthly newsletter https://mailchi.mp/honest/the-honest-channel-newsletter 📕 Read my fictional novel, From the Outside https://amzn.to/4mJ3Pbf 🛍️ Shop my recommended skin and lifestyle products https://shopmy.us/TheHonestChannel 🎧 Listen to the podcast with YouTube Music https://musi https://www.youtube-nocookie.com/embed/PHV_VI1SKCg 1576 2025-08-24T16:00:37.000Z 2026-10-22T19:43:45.565Z https://longevityharbor.com/de/watch/PHV_VI1SKCg Healthy Aging Diet, Supplements & Gadgets My Parents Use In Their 80s | Rebuilding Mum & Dad https://i.ytimg.com/vi/PHV_VI1SKCg/hqdefault.jpg In this episode of Rebuilding Mum & Dad, I take you inside my parents’ daily routine. You'll find the supplements and tools discussed here https://shopmy.us/shop/collections/408665 In this video you’ll discover: What my mum and dad eat each day (and why they’ve stuck to a Mediterranean-style diet) The supplements they feel help with energy, immunity, and joint health – including NMN Simple lifestyle tools they use, from red light therapy to a home climber My mum’s pared-back skincare routine in her 80s Article summarizing their regimen https://www.honest.scot/health-fitness/mum-dads-healthy-aging-regimen-in-their-80s/ Mum’s skincare routine https://shopmy.us/collections/2114168 👉 More related content: Science behind their regimen https://www.honest.scot/health-fitness/anti-aging-supplements-what-a-shock-multivitamin-study-tells-us/ Natural hair loss solutions we’ve tried https://www.honest.scot/skincare/hair-care/the-best-natural-solution-for-thinning-hair/ More about NMN and why we take it https://youtu.be/BP_IJ3sbKQc My Parents' Strength Training Regimen Explained: https://www.honest.scot/health-fitness/rebuilding-mum-dad-our-strength-training-regimen/ 👉 Rebuilding Mum & Dad playlist: https://www.youtube.com/playlist?list=PLwJwOmOzK8TBO3RfJC4LXOvzShe2ALNds The Honest Channel is hosted by me, Clare Johnston, a journalist in my 50s dedicated to exploring skincare and healthy aging. Here's how you can access more from me: 🤝 Join The Honest Channel and gain access to member posts and perks https://www.youtube.com/channel/UC4qU47VfUwFLDzolJEczYCA/join ✅ Subscribe for more episodes https://www.youtube.com/thehonestchannel 📖 Keep up with my articles on skincare and healthy aging http://www.honest.scot 🚨 Receive my monthly newsletter https://mailchi.mp/honest/the-honest-channel-newsletter 📕 Read my fictional novel, From the Outside https://amzn.to/4mJ3Pbf 🛍️ Shop my recommended skin and lifestyle products https://shopmy.us/TheHonestChannel 🎧 Listen to the podcast with YouTube Music https://musi https://www.youtube-nocookie.com/embed/PHV_VI1SKCg 1576 2025-08-24T16:00:37.000Z 2026-10-22T19:43:45.565Z https://longevityharbor.com/en/watch/PKR_7CSDaM0 Pro athlete: Best workout for healthy aging and longevity | Gabby Reece & Dr. Federica Amati https://i.ytimg.com/vi/PKR_7CSDaM0/hqdefault.jpg 🥑 Make smarter food choices. Become a member at http://zoe.com Staying fit isn’t just for athletes - it’s a lifelong commitment that evolves with age. But how do we maintain strength, resilience, and motivation through different life stages? In this episode, Gabby Reece, legendary volleyball player and fitness leader, shares how she has adapted her training over nearly 40 years. From her peak as a professional athlete to balancing fitness with motherhood and now prioritizing longevity at 54, Gabby reveals what has kept her consistent and injury-free. She’s joined by Dr. Federica Amati, Head Nutritionist at ZOE and best-selling author of Every Body Should Know This, who explains how our movement and nutritional needs change over time. Together, they discuss the science behind exercise at every age, why midlife fitness is crucial for preventing frailty, and practical strategies to stay active for the long run. Whether you're starting fresh or looking to refine your routine, this episode will inspire you to train smarter and stay strong for life. 🌱 Try our new plant based wholefood supplement - Daily30: https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=podcast_platform&utm_campaign=d30 Follow ZOE on Instagram | https://www.instagram.com/zoe/ Timecodes 00:00 Try THIS trick 01:57 Quickfire questions 03:50 From college kid to pro-athlete 05:30 Risks of repetitive exercise 06:05 Best injury prevention tips 07:10 Prehab vs rehab 12:20 Fitness during pregnancy 17:20 Keeping fit with a family 22:12 How to workout in your 50s 24:30 How to age better 27:44 This makes you feel better instantly 29:20 The truth about core workouts 31:48 Foot strength in older age 35:40 3 ways to stick to your fitness plan 42:28 You need this everyday 46:35 Get outside for this many minutes each day 48:10 Give yourself a 90 day reset 📚Books by our ZOE Scientists The Food For Life Cookbook | https://amzn.to/4amfIMX Every Body Should Know This by Dr Federica Amati | https://amzn.to/4blJsLg Food For Life by Prof. Tim Spector https://www.youtube-nocookie.com/embed/PKR_7CSDaM0 3284 2025-03-13T16:06:00.000Z 2026-10-22T18:43:11.834Z https://longevityharbor.com/de/watch/PKR_7CSDaM0 Pro athlete: Best workout for healthy aging and longevity | Gabby Reece & Dr. Federica Amati https://i.ytimg.com/vi/PKR_7CSDaM0/hqdefault.jpg 🥑 Make smarter food choices. Become a member at http://zoe.com Staying fit isn’t just for athletes - it’s a lifelong commitment that evolves with age. But how do we maintain strength, resilience, and motivation through different life stages? In this episode, Gabby Reece, legendary volleyball player and fitness leader, shares how she has adapted her training over nearly 40 years. From her peak as a professional athlete to balancing fitness with motherhood and now prioritizing longevity at 54, Gabby reveals what has kept her consistent and injury-free. She’s joined by Dr. Federica Amati, Head Nutritionist at ZOE and best-selling author of Every Body Should Know This, who explains how our movement and nutritional needs change over time. Together, they discuss the science behind exercise at every age, why midlife fitness is crucial for preventing frailty, and practical strategies to stay active for the long run. Whether you're starting fresh or looking to refine your routine, this episode will inspire you to train smarter and stay strong for life. 🌱 Try our new plant based wholefood supplement - Daily30: https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=podcast_platform&utm_campaign=d30 Follow ZOE on Instagram | https://www.instagram.com/zoe/ Timecodes 00:00 Try THIS trick 01:57 Quickfire questions 03:50 From college kid to pro-athlete 05:30 Risks of repetitive exercise 06:05 Best injury prevention tips 07:10 Prehab vs rehab 12:20 Fitness during pregnancy 17:20 Keeping fit with a family 22:12 How to workout in your 50s 24:30 How to age better 27:44 This makes you feel better instantly 29:20 The truth about core workouts 31:48 Foot strength in older age 35:40 3 ways to stick to your fitness plan 42:28 You need this everyday 46:35 Get outside for this many minutes each day 48:10 Give yourself a 90 day reset 📚Books by our ZOE Scientists The Food For Life Cookbook | https://amzn.to/4amfIMX Every Body Should Know This by Dr Federica Amati | https://amzn.to/4blJsLg Food For Life by Prof. Tim Spector https://www.youtube-nocookie.com/embed/PKR_7CSDaM0 3284 2025-03-13T16:06:00.000Z 2026-10-22T18:43:11.834Z https://longevityharbor.com/en/watch/PQljZwTMWgU The Future of Longevity & Geroscience Research https://i.ytimg.com/vi/PQljZwTMWgU/hqdefault.jpg Welcome and Overview Of ABMR : The Future of Longevity & Geroscience Research with Elissa Epel, PhD, President of ABMR. https://www.youtube-nocookie.com/embed/PQljZwTMWgU 1859 2022-06-13T21:43:06.000Z 2026-10-22T17:43:40.111Z https://longevityharbor.com/de/watch/PQljZwTMWgU The Future of Longevity & Geroscience Research https://i.ytimg.com/vi/PQljZwTMWgU/hqdefault.jpg Welcome and Overview Of ABMR : The Future of Longevity & Geroscience Research with Elissa Epel, PhD, President of ABMR. https://www.youtube-nocookie.com/embed/PQljZwTMWgU 1859 2022-06-13T21:43:06.000Z 2026-10-22T17:43:40.111Z https://longevityharbor.com/en/watch/PRi_qm0mUWA 4 3 Fasting vs https://i.ytimg.com/vi/PRi_qm0mUWA/hqdefault.jpg ABOUT TIMELESS AGING Timeless Aging explores the science of healthier aging — including metabolic health, nutrition, exercise, weight management, supplements, emerging longevity research and my own experience trying to improve my health as I get older. 📘 Learn more about the Timeless Aging book: https://timelessagingbook.com/ MEDICAL DISCLAIMER This content is provided for educational and informational purposes only and is not medical advice. I discuss research and may share my personal experiences, but I do not recommend medications, peptides, supplements, dosages or treatment protocols. Always discuss medical decisions with a qualified healthcare professional. #TimelessAging #HealthyAging #Longevity #Over50Health #MetabolicHealth https://www.youtube-nocookie.com/embed/PRi_qm0mUWA 385 2026-09-08T17:14:50.000Z 2026-10-22T19:54:18.091Z https://longevityharbor.com/de/watch/PRi_qm0mUWA 4 3 Fasting vs https://i.ytimg.com/vi/PRi_qm0mUWA/hqdefault.jpg ABOUT TIMELESS AGING Timeless Aging explores the science of healthier aging — including metabolic health, nutrition, exercise, weight management, supplements, emerging longevity research and my own experience trying to improve my health as I get older. 📘 Learn more about the Timeless Aging book: https://timelessagingbook.com/ MEDICAL DISCLAIMER This content is provided for educational and informational purposes only and is not medical advice. I discuss research and may share my personal experiences, but I do not recommend medications, peptides, supplements, dosages or treatment protocols. Always discuss medical decisions with a qualified healthcare professional. #TimelessAging #HealthyAging #Longevity #Over50Health #MetabolicHealth https://www.youtube-nocookie.com/embed/PRi_qm0mUWA 385 2026-09-08T17:14:50.000Z 2026-10-22T19:54:18.091Z https://longevityharbor.com/en/watch/PTQtlplDhLU 2.2.23 Grand Rounds: Age-Related Diseases, Cellular Senescence, and Senolytic Agents: The Path to... https://i.ytimg.com/vi/PTQtlplDhLU/hqdefault.jpg ** This medical education program may contain graphic content. ** _________________________________ A DeBakey CV Education event Presented by Houston Methodist DeBakey Heart & Vascular Center. Building on Dr. Michael E. DeBakey’s commitment to excellence in education, Houston Methodist DeBakey CV Education is an epicenter for cardiovascular academic and clinical educational programs that support the provision of optimal care to patients suffering from cardiovascular conditions and diseases. FOR MORE INFORMATION DeBakey CV Education: https://www.houstonmethodist.org/education/medical/debakey-cv-education For the latest education and training opportunities from DeBakey CV Education: http://bit.ly/HMdebakeyemail Follow Us: Facebook: https://www.facebook.com/debakeycvedu Twitter: https://twitter.com/DeBakeyCVedu Livestream: https://livestream.com/debakey SmugMug: https://debakey.smugmug.com/ Want concise, relevant reviews of the hottest topics in CV medicine? Subscribe for FREE to the Methodist DeBakey Cardiovascular Journal for quarterly, peer-reviewed issues delivered to your door. https://journal.houstonmethodist.org/ https://www.youtube-nocookie.com/embed/PTQtlplDhLU 4154 2023-02-02T15:28:54.000Z 2026-10-23T02:56:02.566Z https://longevityharbor.com/de/watch/PTQtlplDhLU 2.2.23 Grand Rounds: Age-Related Diseases, Cellular Senescence, and Senolytic Agents: The Path to... https://i.ytimg.com/vi/PTQtlplDhLU/hqdefault.jpg ** This medical education program may contain graphic content. ** _________________________________ A DeBakey CV Education event Presented by Houston Methodist DeBakey Heart & Vascular Center. Building on Dr. Michael E. DeBakey’s commitment to excellence in education, Houston Methodist DeBakey CV Education is an epicenter for cardiovascular academic and clinical educational programs that support the provision of optimal care to patients suffering from cardiovascular conditions and diseases. FOR MORE INFORMATION DeBakey CV Education: https://www.houstonmethodist.org/education/medical/debakey-cv-education For the latest education and training opportunities from DeBakey CV Education: http://bit.ly/HMdebakeyemail Follow Us: Facebook: https://www.facebook.com/debakeycvedu Twitter: https://twitter.com/DeBakeyCVedu Livestream: https://livestream.com/debakey SmugMug: https://debakey.smugmug.com/ Want concise, relevant reviews of the hottest topics in CV medicine? Subscribe for FREE to the Methodist DeBakey Cardiovascular Journal for quarterly, peer-reviewed issues delivered to your door. https://journal.houstonmethodist.org/ https://www.youtube-nocookie.com/embed/PTQtlplDhLU 4154 2023-02-02T15:28:54.000Z 2026-10-23T02:56:02.566Z https://longevityharbor.com/en/watch/PU-Awb5rBWc Gesundheit und Jugend - Dank Proteinen? | Ganze Doku https://i.ytimg.com/vi/PU-Awb5rBWc/hqdefault.jpg Proteine bekämpfen #Krankheitserreger, transportieren Sauerstoff und regulieren das #Zellwachstum. Sie steuern lebenswichtige Prozesse und stehen jetzt im Zentrum einer biomedizinischen #Revolution. Neue Technologien entschlüsseln ihre Geheimnisse – mit dem Potenzial, #Krankheiten zu besiegen und das #Altern neu zu definieren. Die NANO Doku zeigt den Stand der aktuellen Forschung über die oft unterschätzten Bausteine des Lebens. NANO – das Wissenschaftsmagazin auf 3sat  Mehr unter: https://kurz.3sat.de/FLG/ Noch mehr spannende Wissenschafts-Dokus: https://kurz.3sat.de/PjM/ https://www.youtube-nocookie.com/embed/PU-Awb5rBWc 2637 2025-09-18T14:00:51.000Z 2026-10-22T20:11:49.401Z https://longevityharbor.com/de/watch/PU-Awb5rBWc Gesundheit und Jugend - Dank Proteinen? | Ganze Doku https://i.ytimg.com/vi/PU-Awb5rBWc/hqdefault.jpg Proteine bekämpfen #Krankheitserreger, transportieren Sauerstoff und regulieren das #Zellwachstum. Sie steuern lebenswichtige Prozesse und stehen jetzt im Zentrum einer biomedizinischen #Revolution. Neue Technologien entschlüsseln ihre Geheimnisse – mit dem Potenzial, #Krankheiten zu besiegen und das #Altern neu zu definieren. Die NANO Doku zeigt den Stand der aktuellen Forschung über die oft unterschätzten Bausteine des Lebens. NANO – das Wissenschaftsmagazin auf 3sat  Mehr unter: https://kurz.3sat.de/FLG/ Noch mehr spannende Wissenschafts-Dokus: https://kurz.3sat.de/PjM/ https://www.youtube-nocookie.com/embed/PU-Awb5rBWc 2637 2025-09-18T14:00:51.000Z 2026-10-22T20:11:49.401Z https://longevityharbor.com/en/watch/PUuJYYdvBM4 DARTS Assay For Studying Rapamycin/mTOR Interaction-Preview https://i.ytimg.com/vi/PUuJYYdvBM4/hqdefault.jpg Watch the Full Video at https://www.jove.com/v/59656/a-semi-quantitative-drug-affinity-responsive-target-stability-darts?utm_source=youtube&utm_medium=social_global&utm_campaign=reseach-videos-2022. A Semi-Quantitative Drug Affinity Responsive Target Stability (DARTS) assay for studying Rapamycin/mTOR interaction - a 2 minute Preview of the Experimental Protocol Chen Zhang, Min Cui, Yazhou Cui, Aubryanna Hettinghouse, Chuan-ju Liu New York University Medical Center, Department of Orthopaedic Surgery; New York University School of Medicine, Department of Cell Biology; In this study, we enhanced the data analysis capabilities of the DARTS experiment by monitoring the changes in protein stability and estimating the affinity of protein-ligand interactions. The interactions can be plotted into two curves: a proteolytic curve and a dose-dependence curve. We have used mTOR-rapamycin interaction as an exemplary case. Visit https://www.jove.com?utm_source=youtube&utm_medium=social_global&utm_campaign=reseach-videos-2022 to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: https://www.youtube.com/c/JoVEJournalofVisualizedExperiments https://www.youtube-nocookie.com/embed/PUuJYYdvBM4 121 2022-05-30T15:39:16.000Z 2026-10-22T17:43:41.773Z https://longevityharbor.com/de/watch/PUuJYYdvBM4 DARTS Assay For Studying Rapamycin/mTOR Interaction-Preview https://i.ytimg.com/vi/PUuJYYdvBM4/hqdefault.jpg Watch the Full Video at https://www.jove.com/v/59656/a-semi-quantitative-drug-affinity-responsive-target-stability-darts?utm_source=youtube&utm_medium=social_global&utm_campaign=reseach-videos-2022. A Semi-Quantitative Drug Affinity Responsive Target Stability (DARTS) assay for studying Rapamycin/mTOR interaction - a 2 minute Preview of the Experimental Protocol Chen Zhang, Min Cui, Yazhou Cui, Aubryanna Hettinghouse, Chuan-ju Liu New York University Medical Center, Department of Orthopaedic Surgery; New York University School of Medicine, Department of Cell Biology; In this study, we enhanced the data analysis capabilities of the DARTS experiment by monitoring the changes in protein stability and estimating the affinity of protein-ligand interactions. The interactions can be plotted into two curves: a proteolytic curve and a dose-dependence curve. We have used mTOR-rapamycin interaction as an exemplary case. Visit https://www.jove.com?utm_source=youtube&utm_medium=social_global&utm_campaign=reseach-videos-2022 to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: https://www.youtube.com/c/JoVEJournalofVisualizedExperiments https://www.youtube-nocookie.com/embed/PUuJYYdvBM4 121 2022-05-30T15:39:16.000Z 2026-10-22T17:43:41.773Z https://longevityharbor.com/en/watch/PeT1RcwsDMc The Epigenetic Clock: A Theory and Hope for Growing Old Gracefully | Keith Booher | TEDxTurtleRock https://i.ytimg.com/vi/PeT1RcwsDMc/hqdefault.jpg "The world population is aging, especially in the West and the industrialized countries of Asia. In fact, the percentage of the population over the age of 65 is expected to more than double by the year 2050. An aging population presents many societal challenges as advanced age is the number one contributor to chronic ailments such as heart disease, cancer, neurological disorders, and more. It is imperative that meaningful and effective anti-aging interventions are identified and deployed in order to ease the transition from a younger to gradually older population. Epigenetics involves the modification of gene expression without changing the underlying DNA sequence. Importantly, many recent scientific studies demonstrate the connection between epigenetics, especially DNA methylation, and aging. To date, analyzing changing DNA methylation patterns at key genes is the most accurate way to quantify the aging process. Understanding the connection between epigenetics and the aging process allows us to gain deeper insight into the mechanisms that cause aging, with the ultimate hope of devising interventions that will potentially lead to better health and longevity. " Post-Doc scientist This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx https://www.youtube-nocookie.com/embed/PeT1RcwsDMc 1095 2019-02-28T19:14:07.000Z 2026-10-22T17:11:30.663Z https://longevityharbor.com/de/watch/PeT1RcwsDMc The Epigenetic Clock: A Theory and Hope for Growing Old Gracefully | Keith Booher | TEDxTurtleRock https://i.ytimg.com/vi/PeT1RcwsDMc/hqdefault.jpg "The world population is aging, especially in the West and the industrialized countries of Asia. In fact, the percentage of the population over the age of 65 is expected to more than double by the year 2050. An aging population presents many societal challenges as advanced age is the number one contributor to chronic ailments such as heart disease, cancer, neurological disorders, and more. It is imperative that meaningful and effective anti-aging interventions are identified and deployed in order to ease the transition from a younger to gradually older population. Epigenetics involves the modification of gene expression without changing the underlying DNA sequence. Importantly, many recent scientific studies demonstrate the connection between epigenetics, especially DNA methylation, and aging. To date, analyzing changing DNA methylation patterns at key genes is the most accurate way to quantify the aging process. Understanding the connection between epigenetics and the aging process allows us to gain deeper insight into the mechanisms that cause aging, with the ultimate hope of devising interventions that will potentially lead to better health and longevity. " Post-Doc scientist This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx https://www.youtube-nocookie.com/embed/PeT1RcwsDMc 1095 2019-02-28T19:14:07.000Z 2026-10-22T17:11:30.663Z https://longevityharbor.com/en/watch/PesNW9f-okc Podcast discusses longevity science, biological age tests and clinic practice https://i.ytimg.com/vi/PesNW9f-okc/hqdefault.jpg In this podcast description, geroscientist Prof. Brian Kennedy discusses moving longevity science into clinical practice, including mTOR and rapamycin, biological age testing, ovarian aging and peptides. https://www.youtube-nocookie.com/embed/PesNW9f-okc 95 2026-08-08T09:03:51.000Z 2026-10-22T23:08:58.711Z https://longevityharbor.com/de/watch/PesNW9f-okc Podcast bespricht Langlebigkeitsforschung, biologische Alterstests und Klinikpraxis https://i.ytimg.com/vi/PesNW9f-okc/hqdefault.jpg In dieser Podcast-Beschreibung spricht der Gerowissenschaftler Prof. Brian Kennedy darüber, Langlebigkeitsforschung in die klinische Praxis zu bringen, darunter mTOR und Rapamycin, biologische Alterstests, Ovarialalterung und Peptide. https://www.youtube-nocookie.com/embed/PesNW9f-okc 95 2026-08-08T09:03:51.000Z 2026-10-22T23:08:58.711Z https://longevityharbor.com/en/watch/PifDVH7Al6Q Kroemer keynote description: ageing biology, autophagy and healthspan https://i.ytimg.com/vi/PifDVH7Al6Q/hqdefault.jpg The description says Kroemer's Milan Longevity Summit 2026 keynote covers cellular and molecular ageing mechanisms and how metabolism, cellular stress, autophagy and longevity research relate to ageing and age-related diseases. https://www.youtube-nocookie.com/embed/PifDVH7Al6Q 2407 2026-08-10T13:56:42.000Z 2026-10-22T23:06:31.925Z https://longevityharbor.com/de/watch/PifDVH7Al6Q Kroemer-Keynote-Beschreibung: Alternsbiologie, Autophagie und Healthspan https://i.ytimg.com/vi/PifDVH7Al6Q/hqdefault.jpg Laut Beschreibung behandelt Kroemers Keynote beim Milan Longevity Summit 2026 zelluläre und molekulare Alternsmechanismen und wie Stoffwechsel, zellulärer Stress, Autophagie und Langlebigkeitsforschung mit Altern und altersassoziierten Krankheiten zusammenhängen. https://www.youtube-nocookie.com/embed/PifDVH7Al6Q 2407 2026-08-10T13:56:42.000Z 2026-10-22T23:06:31.925Z https://longevityharbor.com/en/watch/PonML88XQvU [WEBINAR] Epigenetics of Aging by Prof. Paul Shiels https://i.ytimg.com/vi/PonML88XQvU/hqdefault.jpg Aging results in a gradual and progressive loss of physiological functions and physical abilities over time. Overcoming the growing burden of age-related issues is one of the greatest challenges facing modern society. This webinar covers how these issues are leading to a major drain on healthcare resources worldwide, and why a better understanding of the biology of aging is critically important. https://www.youtube-nocookie.com/embed/PonML88XQvU 3905 2019-11-20T19:05:03.000Z 2026-10-22T17:43:40.188Z https://longevityharbor.com/de/watch/PonML88XQvU [WEBINAR] Epigenetics of Aging by Prof. Paul Shiels https://i.ytimg.com/vi/PonML88XQvU/hqdefault.jpg Aging results in a gradual and progressive loss of physiological functions and physical abilities over time. Overcoming the growing burden of age-related issues is one of the greatest challenges facing modern society. This webinar covers how these issues are leading to a major drain on healthcare resources worldwide, and why a better understanding of the biology of aging is critically important. https://www.youtube-nocookie.com/embed/PonML88XQvU 3905 2019-11-20T19:05:03.000Z 2026-10-22T17:43:40.188Z https://longevityharbor.com/en/watch/PsAF74sa7pY Video description proposes five foods to support healthy aging and slow the biological clock https://i.ytimg.com/vi/PsAF74sa7pY/hqdefault.jpg The description presents five foods it says support healthy aging through autophagy, DNA protection, senolytic action, cellular defense and inflammation support; it calls them no magic solutions and gives no study results. https://www.youtube-nocookie.com/embed/PsAF74sa7pY 279 2026-04-12T05:20:28.000Z 2026-10-23T01:35:29.620Z https://longevityharbor.com/de/watch/PsAF74sa7pY Videobeschreibung schlägt fünf Lebensmittel zur Unterstützung gesunden Alterns und zur Verlangsamung https://i.ytimg.com/vi/PsAF74sa7pY/hqdefault.jpg Die Beschreibung stellt fünf Lebensmittel vor, die gesundes Altern über Autophagie, DNA-Schutz, senolytische Wirkung, Zellschutz und Entzündungsunterstützung fördern sollen; sie nennt sie keine Wundermittel und liefert keine Studienergebnisse. https://www.youtube-nocookie.com/embed/PsAF74sa7pY 279 2026-04-12T05:20:28.000Z 2026-10-23T01:35:29.620Z https://longevityharbor.com/en/watch/PxCjngqK8R8 Moving Beyond Mortality Clocks: Responsive Rate of Aging Biomarkers with Assoc. Professor Dan Belsky https://i.ytimg.com/vi/PxCjngqK8R8/hqdefault.jpg What if the key to healthy aging isn't how old you are, but how fast you're aging? In this episode of Decoding Longevity, Dr. Raghav Sehgal and Dr. Macsue Jacques are joined by Associate Professor Daniel W. Belsky, one of the developers of DunedinPACE, to discuss how measuring the pace of aging could transform longevity research and clinical trials. Together, they explore: • Biological Age vs. Pace of Aging • The landmark Dunedin Study • Why DunedinPACE stands out among aging biomarkers • Insights from the CALERIE trial • The ARPA-H FAST Initiative and the future of aging biomarkers If you enjoyed this episode, don't forget to like, subscribe, and share. #Longevity #HealthyAging #DunedinPACE #BiologicalAge #PaceOfAging #Epigenetics #Geroscience #DecodingLongevity https://www.youtube-nocookie.com/embed/PxCjngqK8R8 2810 2026-08-05T16:10:39.000Z 2026-10-22T19:04:38.877Z https://longevityharbor.com/de/watch/PxCjngqK8R8 Moving Beyond Mortality Clocks: Responsive Rate of Aging Biomarkers with Assoc. Professor Dan Belsky https://i.ytimg.com/vi/PxCjngqK8R8/hqdefault.jpg What if the key to healthy aging isn't how old you are, but how fast you're aging? In this episode of Decoding Longevity, Dr. Raghav Sehgal and Dr. Macsue Jacques are joined by Associate Professor Daniel W. Belsky, one of the developers of DunedinPACE, to discuss how measuring the pace of aging could transform longevity research and clinical trials. Together, they explore: • Biological Age vs. Pace of Aging • The landmark Dunedin Study • Why DunedinPACE stands out among aging biomarkers • Insights from the CALERIE trial • The ARPA-H FAST Initiative and the future of aging biomarkers If you enjoyed this episode, don't forget to like, subscribe, and share. #Longevity #HealthyAging #DunedinPACE #BiologicalAge #PaceOfAging #Epigenetics #Geroscience #DecodingLongevity https://www.youtube-nocookie.com/embed/PxCjngqK8R8 2810 2026-08-05T16:10:39.000Z 2026-10-22T19:04:38.877Z https://longevityharbor.com/en/watch/PyhmvAL-iYw Podcast description: visceral fat, sleep, fasting, plastics and supplements https://i.ytimg.com/vi/PyhmvAL-iYw/hqdefault.jpg The description says biomedical scientist Rhonda Patrick discusses visceral fat, a two-week sleep study linked to 11% more visceral fat, fasting, hormone-disrupting chemicals in plastics, supplements and exercise guidelines. These are creator-attributed topics; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/PyhmvAL-iYw 9590 2026-03-30T07:00:00.000Z 2026-10-23T01:50:20.765Z https://longevityharbor.com/de/watch/PyhmvAL-iYw Podcast-Beschreibung: viszerales Fett, Schlaf, Fasten, Plastik und Supplemente https://i.ytimg.com/vi/PyhmvAL-iYw/hqdefault.jpg Laut Beschreibung spricht die Biomedizinerin Rhonda Patrick über viszerales Fett, eine zweiwöchige Schlafstudie mit 11 % mehr viszeralem Fett, Fasten, hormonstörende Chemikalien in Plastik, Supplemente und Bewegungsrichtlinien. Das sind Angaben des Erstellers; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/PyhmvAL-iYw 9590 2026-03-30T07:00:00.000Z 2026-10-23T01:50:20.765Z https://longevityharbor.com/en/watch/Q-P7ryjS_SY Matt Kaeberlein | Let’s Talk Longevity – Open Q&A | LIC 2025 https://i.ytimg.com/vi/Q-P7ryjS_SY/hqdefault.jpg At the Longevity Investors Conference 2025 in Gstaad, longevity scientist and researcher Matt Kaeberlein joined the Let’s Talk Longevity open Q&A to bring scientific clarity to one of the field’s most debated topics — biological aging clocks. Drawing on two decades of aging-biology research and translational work, Kaeberlein explains why most direct-to-consumer “biological age” tests don’t truly measure aging, and why rigorous validation, precision, and transparency are essential before integrating such tools into clinical practice. He also explores broader themes that define the longevity movement today — from the rise of health-span optimization and lifestyle science to the need for evidence-based decision-making and honest communication between researchers, clinicians, and consumers. 🔹 Key insights: • Why biological aging clocks don’t actually measure biological age • The difference between correlation, precision, and accuracy • Better biomarkers for real-world health prediction • How motivation and transparency can coexist in longevity science • The future of validated diagnostics and longitudinal tracking 🎬 Recorded live at the Longevity Investors Conference 2025 in Gstaad, Switzerland. 📍 Learn more: www.longevityinvestors.ch 📺 Subscribe for more talks and highlights from global leaders in longevity science and investment. #LIC2025 #LongevityInvestors https://www.youtube-nocookie.com/embed/Q-P7ryjS_SY 1552 2025-10-17T12:49:21.000Z 2026-10-22T19:32:34.544Z https://longevityharbor.com/de/watch/Q-P7ryjS_SY Matt Kaeberlein | Let’s Talk Longevity – Open Q&A | LIC 2025 https://i.ytimg.com/vi/Q-P7ryjS_SY/hqdefault.jpg At the Longevity Investors Conference 2025 in Gstaad, longevity scientist and researcher Matt Kaeberlein joined the Let’s Talk Longevity open Q&A to bring scientific clarity to one of the field’s most debated topics — biological aging clocks. Drawing on two decades of aging-biology research and translational work, Kaeberlein explains why most direct-to-consumer “biological age” tests don’t truly measure aging, and why rigorous validation, precision, and transparency are essential before integrating such tools into clinical practice. He also explores broader themes that define the longevity movement today — from the rise of health-span optimization and lifestyle science to the need for evidence-based decision-making and honest communication between researchers, clinicians, and consumers. 🔹 Key insights: • Why biological aging clocks don’t actually measure biological age • The difference between correlation, precision, and accuracy • Better biomarkers for real-world health prediction • How motivation and transparency can coexist in longevity science • The future of validated diagnostics and longitudinal tracking 🎬 Recorded live at the Longevity Investors Conference 2025 in Gstaad, Switzerland. 📍 Learn more: www.longevityinvestors.ch 📺 Subscribe for more talks and highlights from global leaders in longevity science and investment. #LIC2025 #LongevityInvestors https://www.youtube-nocookie.com/embed/Q-P7ryjS_SY 1552 2025-10-17T12:49:21.000Z 2026-10-22T19:32:34.544Z https://longevityharbor.com/en/watch/Q1KkAAmPzxc Podcast clip description: muscle as an organ, myokines and strength training for healthy aging https://i.ytimg.com/vi/Q1KkAAmPzxc/hqdefault.jpg The description says Dr. Marc Weitl explains in a podcast excerpt why muscle mass matters beyond strength, calling it a metabolic and immune organ, and which role strength training, myokines, recovery and heart-rate variability are said to play for healthy aging. https://www.youtube-nocookie.com/embed/Q1KkAAmPzxc 393 2025-12-09T15:30:31.000Z 2026-10-23T03:17:25.500Z https://longevityharbor.com/de/watch/Q1KkAAmPzxc Podcast-Ausschnitt: Muskel als Organ, Myokine und Krafttraining für gesundes Altern https://i.ytimg.com/vi/Q1KkAAmPzxc/hqdefault.jpg Laut Beschreibung erklärt Dr. Marc Weitl in einem Podcast-Ausschnitt, warum Muskelmasse über Kraft hinaus zählt und ein Stoffwechsel- und Immunorgan sei, und welche Rolle Krafttraining, Myokine, Regeneration und Herzratenvariabilität für gesundes Altern spielen sollen. https://www.youtube-nocookie.com/embed/Q1KkAAmPzxc 393 2025-12-09T15:30:31.000Z 2026-10-23T03:17:25.500Z https://longevityharbor.com/en/watch/Q4fTqw9Pw3A Secret to Longevity: The Power of 5-Day Fasting https://i.ytimg.com/vi/Q4fTqw9Pw3A/hqdefault.jpg Hotmail founder Sabeer Bhatia shares his personal journey with longevity and his belief that long-term fasting is the key to reversing ageing. He explains the science behind a 5-day reduced-calorie fast and how it forces the body into a state of autophagy, rejuvenating cells and leading to a longer, healthier life. Learn why he believes this is a trade worth taking and how it has become a crucial part of his life. 📌 Full Episode: Spotify: https://open.spotify.com/episode/0PjEzvVl0i3yAhmXD1nLsw?si=fd90a13e657a4b75 Apple Podcasts: https://podcasts.apple.com/us/podcast/the-man-who-built-hotmail-and-sold-it-to-microsoft/id1488581910?i=1000723874665 📌 Follow us: Instagram: https://www.instagram.com/primevp_in/ Facebook: https://www.facebook.com/profile.php?id=61574450955885 LinkedIn: https://www.linkedin.com/company/primevp Twitter: https://twitter.com/primevp_in Website: https://primevp.in #SabeerBhatia #Longevity #Fasting #Health #Wellness #Outlive #TheLongevityDiet #Startup #Entrepreneur #FastingBenefits #TechLeadership #IndianStartups #EntrepreneurMindset #FutureOfWork #PrimeVenturePartnersPodcast https://www.youtube-nocookie.com/embed/Q4fTqw9Pw3A 137 2025-09-09T05:53:36.000Z 2026-10-22T18:54:06.977Z https://longevityharbor.com/de/watch/Q4fTqw9Pw3A Secret to Longevity: The Power of 5-Day Fasting https://i.ytimg.com/vi/Q4fTqw9Pw3A/hqdefault.jpg Hotmail founder Sabeer Bhatia shares his personal journey with longevity and his belief that long-term fasting is the key to reversing ageing. He explains the science behind a 5-day reduced-calorie fast and how it forces the body into a state of autophagy, rejuvenating cells and leading to a longer, healthier life. Learn why he believes this is a trade worth taking and how it has become a crucial part of his life. 📌 Full Episode: Spotify: https://open.spotify.com/episode/0PjEzvVl0i3yAhmXD1nLsw?si=fd90a13e657a4b75 Apple Podcasts: https://podcasts.apple.com/us/podcast/the-man-who-built-hotmail-and-sold-it-to-microsoft/id1488581910?i=1000723874665 📌 Follow us: Instagram: https://www.instagram.com/primevp_in/ Facebook: https://www.facebook.com/profile.php?id=61574450955885 LinkedIn: https://www.linkedin.com/company/primevp Twitter: https://twitter.com/primevp_in Website: https://primevp.in #SabeerBhatia #Longevity #Fasting #Health #Wellness #Outlive #TheLongevityDiet #Startup #Entrepreneur #FastingBenefits #TechLeadership #IndianStartups #EntrepreneurMindset #FutureOfWork #PrimeVenturePartnersPodcast https://www.youtube-nocookie.com/embed/Q4fTqw9Pw3A 137 2025-09-09T05:53:36.000Z 2026-10-22T18:54:06.977Z https://longevityharbor.com/en/watch/Q7du1kfe9xI Video description: 12 collagen-rich foods and claimed anti-aging effects https://i.ytimg.com/vi/Q7du1kfe9xI/hqdefault.jpg The description presents 12 collagen-rich foods and claims they support collagen production, skin elasticity, joints and healthy aging; it reports no study results. https://www.youtube-nocookie.com/embed/Q7du1kfe9xI 2548 2026-06-20T15:01:23.000Z 2026-10-22T23:53:43.176Z https://longevityharbor.com/de/watch/Q7du1kfe9xI Videobeschreibung: 12 kollagenreiche Lebensmittel und behauptete Anti-Aging-Effekte https://i.ytimg.com/vi/Q7du1kfe9xI/hqdefault.jpg Die Beschreibung stellt 12 kollagenreiche Lebensmittel vor und behauptet, sie unterstützten Kollagenbildung, Hautelastizität, Gelenke und gesundes Altern; Studienergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/Q7du1kfe9xI 2548 2026-06-20T15:01:23.000Z 2026-10-22T23:53:43.176Z https://longevityharbor.com/en/watch/Q818H8Y72MU Video description compares NMN and NR as NAD⁺ precursors for longevity https://i.ytimg.com/vi/Q818H8Y72MU/hqdefault.jpg The description says it examines whether NMN or NR is better for raising NAD⁺, longevity and DNA repair, citing two studies and a medical disclaimer; it reports no results. https://www.youtube-nocookie.com/embed/Q818H8Y72MU 169 2026-04-06T21:00:34.000Z 2026-10-23T01:40:29.553Z https://longevityharbor.com/de/watch/Q818H8Y72MU Videobeschreibung vergleicht NMN und NR als NAD⁺-Vorstufen für Langlebigkeit https://i.ytimg.com/vi/Q818H8Y72MU/hqdefault.jpg Die Beschreibung sagt, sie prüfe, ob NMN oder NR besser zum Erhöhen von NAD⁺, für Langlebigkeit und DNA-Reparatur geeignet ist, nennt zwei Studien und einen medizinischen Hinweis; Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/Q818H8Y72MU 169 2026-04-06T21:00:34.000Z 2026-10-23T01:40:29.553Z https://longevityharbor.com/en/watch/QFRifg0-RHE Video description: five home exercises for muscle loss after 60 https://i.ytimg.com/vi/QFRifg0-RHE/hqdefault.jpg A video description presents five home exercises for older adults to counter sarcopenia, the age-related loss of muscle. It cites studies on bed rest, strength training in people in their 90s, walking and daily steps. The video and transcript were not reviewed, so no findings can be checked. https://www.youtube-nocookie.com/embed/QFRifg0-RHE 1345 2026-10-20T15:00:26.000Z 2026-10-22T19:39:01.740Z https://longevityharbor.com/de/watch/QFRifg0-RHE Videobeschreibung: fünf Übungen zu Hause gegen Muskelverlust nach 60 https://i.ytimg.com/vi/QFRifg0-RHE/hqdefault.jpg Eine Videobeschreibung stellt fünf Übungen für zu Hause vor, mit denen ältere Menschen Sarkopenie entgegenwirken sollen, dem altersbezogenen Muskelverlust. Sie nennt Studien zu Bettruhe, Krafttraining bei Menschen in den 90ern, Gehen und täglichen Schritten. Video und Transkript wurden nicht geprüft, daher lassen sich keine Ergebnisse überprüfen. https://www.youtube-nocookie.com/embed/QFRifg0-RHE 1345 2026-10-20T15:00:26.000Z 2026-10-22T19:39:01.740Z https://longevityharbor.com/en/watch/QGIWAbEpIQ4 Food statt Junk: Der Weg zu gesunder Ernährung | Doku | Gut zu wissen | BR https://i.ytimg.com/vi/QGIWAbEpIQ4/hqdefault.jpg Diese Doku begleitet 3 Menschen, die sich für bessere Ernährung stark machen. 👉 Hier entlang für weitere "Gut zu wissen"-Beiträge in der ARD Mediathek: https://1.ard.de/gut-zu-wissen-start Hochverarbeitete Lebensmittel sind noch ungesünder als lange vermutet. Trotzdem sind die Supermärkte voll davon. Drei Menschen kämpfen für eine gesündere Gesellschaft mit weniger ernährungsbedingten gesundheitlichen Folgen. Eine lösungsorientierte Story von Johanna Rupprecht und Anna-Louise Bath. TV-Ausstrahlung 21.09.2024 In diesem Video werden die Auswirkungen hochverarbeiteter Lebensmittel auf die Gesundheit sowie deren Zusammenhang mit Krankheiten wie Herz-Kreislauf-Erkrankungen, Diabetes und psychischen Störungen beleuchtet. Es wird erklärt, warum natürliche Ernährung Vorteile bietet und wie Zusatzstoffe die Lebensmittelqualität beeinflussen. Zudem wird ein Pilotprojekt begleitet, in dem eine pflanzenbasierte, gesunde Ernährung in einem Krankenhaus getestet wird. Was ein hoher Konsum dieser Produkte in unserem Körper anrichten kann, macht sich nicht sofort, sondern schleichend bemerkbar. Eine Vielzahl langfristig angelegter wissenschaftlicher Beobachtungsstudien warnt vor ihren gesundheitlichen Folgen, z. B. Erkrankungen von Herz und Gefäßen, psychischen Störungen, Fettleibigkeit und Typ-2-Diabetes. Julia Gebendorfer, Pädagogin und Bloggerin, Niklas Oppenrieder, Kinderarzt und NGO-Gründer sowie Hans-Ulrich Grimm, Buchautor und Food-Detektiv, zeigen Wege zu einer gesünderen Ernährung. 👉 Hier entlang für weitere "Gut zu wissen"-Beträge: https://1.ard.de/gut-zu-wissen-start #food #junkfood #ernährung https://www.youtube-nocookie.com/embed/QGIWAbEpIQ4 1720 2024-11-01T07:04:47.000Z 2026-10-22T19:04:44.041Z https://longevityharbor.com/de/watch/QGIWAbEpIQ4 Food statt Junk: Der Weg zu gesunder Ernährung | Doku | Gut zu wissen | BR https://i.ytimg.com/vi/QGIWAbEpIQ4/hqdefault.jpg Diese Doku begleitet 3 Menschen, die sich für bessere Ernährung stark machen. 👉 Hier entlang für weitere "Gut zu wissen"-Beiträge in der ARD Mediathek: https://1.ard.de/gut-zu-wissen-start Hochverarbeitete Lebensmittel sind noch ungesünder als lange vermutet. Trotzdem sind die Supermärkte voll davon. Drei Menschen kämpfen für eine gesündere Gesellschaft mit weniger ernährungsbedingten gesundheitlichen Folgen. Eine lösungsorientierte Story von Johanna Rupprecht und Anna-Louise Bath. TV-Ausstrahlung 21.09.2024 In diesem Video werden die Auswirkungen hochverarbeiteter Lebensmittel auf die Gesundheit sowie deren Zusammenhang mit Krankheiten wie Herz-Kreislauf-Erkrankungen, Diabetes und psychischen Störungen beleuchtet. Es wird erklärt, warum natürliche Ernährung Vorteile bietet und wie Zusatzstoffe die Lebensmittelqualität beeinflussen. Zudem wird ein Pilotprojekt begleitet, in dem eine pflanzenbasierte, gesunde Ernährung in einem Krankenhaus getestet wird. Was ein hoher Konsum dieser Produkte in unserem Körper anrichten kann, macht sich nicht sofort, sondern schleichend bemerkbar. Eine Vielzahl langfristig angelegter wissenschaftlicher Beobachtungsstudien warnt vor ihren gesundheitlichen Folgen, z. B. Erkrankungen von Herz und Gefäßen, psychischen Störungen, Fettleibigkeit und Typ-2-Diabetes. Julia Gebendorfer, Pädagogin und Bloggerin, Niklas Oppenrieder, Kinderarzt und NGO-Gründer sowie Hans-Ulrich Grimm, Buchautor und Food-Detektiv, zeigen Wege zu einer gesünderen Ernährung. 👉 Hier entlang für weitere "Gut zu wissen"-Beträge: https://1.ard.de/gut-zu-wissen-start #food #junkfood #ernährung https://www.youtube-nocookie.com/embed/QGIWAbEpIQ4 1720 2024-11-01T07:04:47.000Z 2026-10-22T19:04:44.041Z https://longevityharbor.com/en/watch/QIvzNpLz0fw Epigenetic clocks: estimating biological age from DNA methylation https://i.ytimg.com/vi/QIvzNpLz0fw/hqdefault.jpg The description says epigenetic clocks are tools that estimate biological aging through DNA methylation patterns, and that these signatures reflect influences of lifestyle, environment and metabolic stress on cellular aging. https://www.youtube-nocookie.com/embed/QIvzNpLz0fw 417 2026-03-08T18:05:00.000Z 2026-10-23T02:11:55.128Z https://longevityharbor.com/de/watch/QIvzNpLz0fw Epigenetische Uhren: biologisches Alter über DNA-Methylierung schätzen https://i.ytimg.com/vi/QIvzNpLz0fw/hqdefault.jpg Laut Beschreibung sind epigenetische Uhren Werkzeuge, die biologisches Altern über DNA-Methylierungsmuster schätzen; diese Signaturen spiegeln demnach Einflüsse von Lebensstil, Umwelt und metabolischem Stress auf die zelluläre Alterung. https://www.youtube-nocookie.com/embed/QIvzNpLz0fw 417 2026-03-08T18:05:00.000Z 2026-10-23T02:11:55.128Z https://longevityharbor.com/en/watch/QL2p2oMIxYM Meistgehört: Muskelaufbau und Training im Alter – Dr. Ingo Froböse & Nina Ruge https://i.ytimg.com/vi/QL2p2oMIxYM/hqdefault.jpg In dieser Folge spreche ich mit Dr. Ingo Froböse, einem der profiliertesten Sportwissenschaftler Deutschlands, über die zentrale Rolle der Muskulatur für gesunde Langlebigkeit. Muskeln sind weit mehr als ein Bewegungsapparat – sie beeinflussen Stoffwechsel, Immunfunktion, Hormonhaushalt und sogar das Risiko für schwere chronische Erkrankungen. Wir sprechen darüber, warum Muskelabbau kein unvermeidbares Schicksal ist, welche biologischen Prozesse hinter Dynapenie und Sarkopenie stehen und weshalb Krafttraining gerade im zweiten Lebensabschnitt entscheidend wird. Diese Folge zeigt, wie Bewegung im Alltag, gezieltes Training und ein bewusster Lebensstil unsere Vitalität bis ins hohe Alter erhalten können. In dieser Folge sprechen wir u.a. über folgende Themen: - Warum sind Muskeln ein zentraler Faktor für gesunde Langlebigkeit? - Ab welchem Alter beginnt der altersbedingte Kraftverlust? - Was unterscheidet Dynapenie von Sarkopenie? - Welche Rolle spielen Nerv-Muskel-Verbindungen im Alterungsprozess? - Wie beeinflusst Bewegungsmangel die Muskelentwicklung bei Kindern? - Warum sind weiße Muskelfasern besonders wichtig für Sturzprävention? - Welche Rolle spielen Mitochondrien für Muskelkraft und Energie? - Warum schützt Muskeltraining vor Diabetes Typ 2? - Warum reichen Gleichgewichtsübungen allein nicht aus? - Wie kann gezieltes Krafttraining den Alterungsprozess bremsen? Weitere Informationen zu Prof. Dr. Ingo Froböse findest du hier: https://www.ingo-froboese.de Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder YouTube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an d https://www.youtube-nocookie.com/embed/QL2p2oMIxYM 3785 2026-01-11T10:37:05.000Z 2026-10-22T18:54:05.002Z https://longevityharbor.com/de/watch/QL2p2oMIxYM Meistgehört: Muskelaufbau und Training im Alter – Dr. Ingo Froböse & Nina Ruge https://i.ytimg.com/vi/QL2p2oMIxYM/hqdefault.jpg In dieser Folge spreche ich mit Dr. Ingo Froböse, einem der profiliertesten Sportwissenschaftler Deutschlands, über die zentrale Rolle der Muskulatur für gesunde Langlebigkeit. Muskeln sind weit mehr als ein Bewegungsapparat – sie beeinflussen Stoffwechsel, Immunfunktion, Hormonhaushalt und sogar das Risiko für schwere chronische Erkrankungen. Wir sprechen darüber, warum Muskelabbau kein unvermeidbares Schicksal ist, welche biologischen Prozesse hinter Dynapenie und Sarkopenie stehen und weshalb Krafttraining gerade im zweiten Lebensabschnitt entscheidend wird. Diese Folge zeigt, wie Bewegung im Alltag, gezieltes Training und ein bewusster Lebensstil unsere Vitalität bis ins hohe Alter erhalten können. In dieser Folge sprechen wir u.a. über folgende Themen: - Warum sind Muskeln ein zentraler Faktor für gesunde Langlebigkeit? - Ab welchem Alter beginnt der altersbedingte Kraftverlust? - Was unterscheidet Dynapenie von Sarkopenie? - Welche Rolle spielen Nerv-Muskel-Verbindungen im Alterungsprozess? - Wie beeinflusst Bewegungsmangel die Muskelentwicklung bei Kindern? - Warum sind weiße Muskelfasern besonders wichtig für Sturzprävention? - Welche Rolle spielen Mitochondrien für Muskelkraft und Energie? - Warum schützt Muskeltraining vor Diabetes Typ 2? - Warum reichen Gleichgewichtsübungen allein nicht aus? - Wie kann gezieltes Krafttraining den Alterungsprozess bremsen? Weitere Informationen zu Prof. Dr. Ingo Froböse findest du hier: https://www.ingo-froboese.de Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder YouTube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an d https://www.youtube-nocookie.com/embed/QL2p2oMIxYM 3785 2026-01-11T10:37:05.000Z 2026-10-22T18:54:05.002Z https://longevityharbor.com/en/watch/QLI7YB8gBlI Exercise, DEAF1 and aging muscle: a video description explainer https://i.ytimg.com/vi/QLI7YB8gBlI/hqdefault.jpg The description reports a study linking exercise to lower DEAF1, normalized mTORC1 activity and better protein balance in aging muscle; fly and mouse experiments support the mechanism. https://www.youtube-nocookie.com/embed/QLI7YB8gBlI 162 2026-07-09T06:00:30.000Z 2026-10-22T23:41:09.961Z https://longevityharbor.com/de/watch/QLI7YB8gBlI Bewegung, DEAF1 und alternde Muskeln: ein Erklärstück zur Videobeschreibung https://i.ytimg.com/vi/QLI7YB8gBlI/hqdefault.jpg Die Beschreibung berichtet von einer Studie, die Bewegung mit weniger DEAF1, normalisierter mTORC1-Aktivität und besserem Protein-Gleichgewicht in alternden Muskeln verbindet; Versuche an Fliegen und Mäusen stützen den Mechanismus. https://www.youtube-nocookie.com/embed/QLI7YB8gBlI 162 2026-07-09T06:00:30.000Z 2026-10-22T23:41:09.961Z https://longevityharbor.com/en/watch/QNbj7RXW1AY Rapamycin vs Placebo, Both With Home Exercise, in Adults 65–85 https://i.ytimg.com/vi/QNbj7RXW1AY/hqdefault.jpg A description of a video about the RAPA-EX-01 trial: adults aged 65 to 85 all did the same home workout, half took weekly sirolimus and half placebo, and the placebo group gained more strength. The description says blocking mTOR may blunt muscle building during training. https://www.youtube-nocookie.com/embed/QNbj7RXW1AY 91 2026-10-19T17:00:15.000Z 2026-10-22T20:11:23.485Z https://longevityharbor.com/de/watch/QNbj7RXW1AY Rapamycin gegen Placebo, beide mit Heimtraining, bei Erwachsenen 65–85 https://i.ytimg.com/vi/QNbj7RXW1AY/hqdefault.jpg Eine Beschreibung eines Videos zur RAPA-EX-01-Studie: Erwachsene von 65 bis 85 machten alle dasselbe Heimtraining, die Hälfte nahm wöchentlich Sirolimus, die andere Placebo, und die Placebo-Gruppe gewann mehr Kraft. Laut Beschreibung könnte eine mTOR-Blockade den Muskelaufbau beim Training dämpfen. https://www.youtube-nocookie.com/embed/QNbj7RXW1AY 91 2026-10-19T17:00:15.000Z 2026-10-22T20:11:23.485Z https://longevityharbor.com/en/watch/QPkgZcklLY4 Top 7 Lebensmittel für Longevity: Schaffen wir so ein längeres und gesünderes Leben? https://i.ytimg.com/vi/QPkgZcklLY4/hqdefault.jpg Gesund und langsam zu altern ist das Ziel vieler Menschen. Dabei spielt die richtige Ernährung eine entscheidende Rolle. Obst und Gemüse sind allgemein bekannt für ihre positiven Effekte auf die Gesundheit, doch es gibt spezifische Lebensmittel und -gruppen, die besonders vorteilhaft sind, um altersbedingte Beschwerden zu verhindern. Die folgenden sieben Lebensmittel helfen dabei, länger gesund zu bleiben und eine hohe Lebensqualität zu bewahren. ⏩ Erst informieren, dann supplementieren: Gerne schauen Sie einmal rein in meine Ratgeber https://bit.ly/RatgeberHowTo ✅ ❎ 100 % unabhängig ❎ 100 % studienbasiert ❎ 100 % medizinisch korrekt 00:00 | Lebensmittel für Longevity 02:12 | Grünes Gemüse - Klassischer Allrounder 05:03 | Beeren - heimisches Superfood 06:21 | Nüsse- Mein persönlicher Dauerbrenner 07:41 | Fisch- Die Omega-3-Power für Ihr Herz 09:54 | Leinsamen- Förderung der Darmgesundheit 13:23 | Hülsenfrüchte - Eine wahre Proteinbombe 15:51 | Probiotika und Präbiotika 17:22 | Was sollten Sie noch beachten? Weitere Tipps #ernährungsmedizin #gesundeernährung #medizin #gesundheit 1. Grünes Gemüse – Der Allrounder für Nährstoffe Grünes Gemüse wie Spinat, Brokkoli, Mangold oder Grünkohl enthält eine Vielzahl von Vitaminen, Mineralstoffen und Ballaststoffen. Diese Nahrungsmittel sind reich an Chlorophyll, dem grünen Farbstoff, der antioxidativ wirkt und den Sauerstofftransport in den Blutgefäßen unterstützt. Kalzium und Kalium, die ebenfalls in diesen Gemüsesorten vorkommen, sind essentiell für starke Knochen, gesunde Muskeln und die Regulierung des Blutdrucks. Grünes Gemüse hat einen niedrigen Kaloriengehalt und lässt sich leicht in verschiedene Gerichte integrieren, sei es als Salat, gedünstet oder als Zutat in einem Smoothie. 2. Beeren – Heimisches Superfood Beeren, insbesondere Blaubeeren, sind wahre Gesundheitsbooster. Sie enthalten Anthocyane, die für ihre entzündungshemmenden und antioxidativen Eigenschaften bekannt sind. Diese Stoffe können das Risiko von Herz-Kreislauf-Erkrankungen senken und schütze https://www.youtube-nocookie.com/embed/QPkgZcklLY4 1187 2024-11-04T16:15:01.000Z 2026-10-22T18:43:10.868Z https://longevityharbor.com/de/watch/QPkgZcklLY4 Top 7 Lebensmittel für Longevity: Schaffen wir so ein längeres und gesünderes Leben? https://i.ytimg.com/vi/QPkgZcklLY4/hqdefault.jpg Gesund und langsam zu altern ist das Ziel vieler Menschen. Dabei spielt die richtige Ernährung eine entscheidende Rolle. Obst und Gemüse sind allgemein bekannt für ihre positiven Effekte auf die Gesundheit, doch es gibt spezifische Lebensmittel und -gruppen, die besonders vorteilhaft sind, um altersbedingte Beschwerden zu verhindern. Die folgenden sieben Lebensmittel helfen dabei, länger gesund zu bleiben und eine hohe Lebensqualität zu bewahren. ⏩ Erst informieren, dann supplementieren: Gerne schauen Sie einmal rein in meine Ratgeber https://bit.ly/RatgeberHowTo ✅ ❎ 100 % unabhängig ❎ 100 % studienbasiert ❎ 100 % medizinisch korrekt 00:00 | Lebensmittel für Longevity 02:12 | Grünes Gemüse - Klassischer Allrounder 05:03 | Beeren - heimisches Superfood 06:21 | Nüsse- Mein persönlicher Dauerbrenner 07:41 | Fisch- Die Omega-3-Power für Ihr Herz 09:54 | Leinsamen- Förderung der Darmgesundheit 13:23 | Hülsenfrüchte - Eine wahre Proteinbombe 15:51 | Probiotika und Präbiotika 17:22 | Was sollten Sie noch beachten? Weitere Tipps #ernährungsmedizin #gesundeernährung #medizin #gesundheit 1. Grünes Gemüse – Der Allrounder für Nährstoffe Grünes Gemüse wie Spinat, Brokkoli, Mangold oder Grünkohl enthält eine Vielzahl von Vitaminen, Mineralstoffen und Ballaststoffen. Diese Nahrungsmittel sind reich an Chlorophyll, dem grünen Farbstoff, der antioxidativ wirkt und den Sauerstofftransport in den Blutgefäßen unterstützt. Kalzium und Kalium, die ebenfalls in diesen Gemüsesorten vorkommen, sind essentiell für starke Knochen, gesunde Muskeln und die Regulierung des Blutdrucks. Grünes Gemüse hat einen niedrigen Kaloriengehalt und lässt sich leicht in verschiedene Gerichte integrieren, sei es als Salat, gedünstet oder als Zutat in einem Smoothie. 2. Beeren – Heimisches Superfood Beeren, insbesondere Blaubeeren, sind wahre Gesundheitsbooster. Sie enthalten Anthocyane, die für ihre entzündungshemmenden und antioxidativen Eigenschaften bekannt sind. Diese Stoffe können das Risiko von Herz-Kreislauf-Erkrankungen senken und schütze https://www.youtube-nocookie.com/embed/QPkgZcklLY4 1187 2024-11-04T16:15:01.000Z 2026-10-22T18:43:10.868Z https://longevityharbor.com/en/watch/QTpqbfMf5wM Healthy Aging: Social and Societal Implications https://i.ytimg.com/vi/QTpqbfMf5wM/hqdefault.jpg S. Jay Olshansky, Ph.D., shares how science is unlocking the secrets of aging. Learn how we can live healthier and longer lives by understanding the biology of aging. Find out about potential breakthroughs and the impact of genetics on diseases like cancer and Alzheimer's. Explore the "longevity dividend" and the quest to compress the "red zone" of aging. [11/2023] [Show ID: 39126] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More from: Healthy Longevity (https://www.uctv.tv/healthy-longevity) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/QTpqbfMf5wM 2471 2023-10-28T02:00:16.000Z 2026-10-22T18:43:11.685Z https://longevityharbor.com/de/watch/QTpqbfMf5wM Healthy Aging: Social and Societal Implications https://i.ytimg.com/vi/QTpqbfMf5wM/hqdefault.jpg S. Jay Olshansky, Ph.D., shares how science is unlocking the secrets of aging. Learn how we can live healthier and longer lives by understanding the biology of aging. Find out about potential breakthroughs and the impact of genetics on diseases like cancer and Alzheimer's. Explore the "longevity dividend" and the quest to compress the "red zone" of aging. [11/2023] [Show ID: 39126] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More from: Healthy Longevity (https://www.uctv.tv/healthy-longevity) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/QTpqbfMf5wM 2471 2023-10-28T02:00:16.000Z 2026-10-22T18:43:11.685Z https://longevityharbor.com/en/watch/QakbhkjaCyU Rapamycin: The Breakthrough Drug for Longevity? https://i.ytimg.com/vi/QakbhkjaCyU/hqdefault.jpg Explore the fascinating world of Rapamycin, a groundbreaking drug with the potential to extend lifespan. This video dives into how Rapamycin works, its unique effects on the mTOR pathway, and why it's considered one of the most promising compounds in longevity research. Discover how it compares to other popular longevity treatments like resveratrol and NAD, and why its consistent results in studies make it stand out. Join us as we uncover the science behind this extraordinary drug and its implications for the future of aging and health. https://www.youtube-nocookie.com/embed/QakbhkjaCyU 709 2024-08-23T12:05:46.000Z 2026-10-22T19:54:22.514Z https://longevityharbor.com/de/watch/QakbhkjaCyU Rapamycin: The Breakthrough Drug for Longevity? https://i.ytimg.com/vi/QakbhkjaCyU/hqdefault.jpg Explore the fascinating world of Rapamycin, a groundbreaking drug with the potential to extend lifespan. This video dives into how Rapamycin works, its unique effects on the mTOR pathway, and why it's considered one of the most promising compounds in longevity research. Discover how it compares to other popular longevity treatments like resveratrol and NAD, and why its consistent results in studies make it stand out. Join us as we uncover the science behind this extraordinary drug and its implications for the future of aging and health. https://www.youtube-nocookie.com/embed/QakbhkjaCyU 709 2024-08-23T12:05:46.000Z 2026-10-22T19:54:22.514Z https://longevityharbor.com/en/watch/Qd3PZHnf53M How to Heal from Chronic Inflammation with Len De Nys | AFP 41 https://i.ytimg.com/vi/Qd3PZHnf53M/hqdefault.jpg Struggling with fatigue, brain fog, or joint pain? You might be battling chronic inflammation. Join Jeroen Schreel and Len De Nys, a postdoctoral researcher at Vrije Universiteit Brussel, as they uncover how to heal from chronic inflammation and prevent the root causes of modern chronic diseases. Len shares his personal story of reversing severe back pain and brain fog through an anti-inflammatory lifestyle, breaking down the phenomenon of "inflammaging" (how aging drives inflammation), how to test your body for chronic inflammation using CRP markers, and how to use lifestyle as a medicine (nutrition, exercise, sleep, and stress management) to protect your DNA and live longer. 00:00 Intro 00:41 Ad 01:50 Meet Len De Nys & The Naked Mole Rat Longevity Secret 03:32 Acute vs. Chronic Inflammation Explained 05:11 What is Inflammaging? (The Hallmarks of Aging) 07:15 Len’s Personal Story: Curing Back Pain & Brain Fog 10:46 How to Diagnose Chronic Inflammation (CRP Tests & Symptoms) 13:19 The Top 5 Killer Diseases Driven by Inflammation 15:30 Genetics vs. Epigenetics: What Pulls the Trigger? 17:05 Pillar 1: Anti-Inflammatory Nutrition & Foods to Avoid 21:35 Time-Restricted Eating & Intermittent Fasting benefits 23:40 Omega-3 Fats & Vegan Algae Alternatives 25:50 Pillar 2: How Exercise Trains Your Immune System 28:04 How Much Cardio & Power Training Do You Need? 31:12 The Danger of Under-Resting & Overtraining 33:14 Pillar 3: How Poor Sleep Destroys Your Immune System 35:31 How to Reset Your Circadian Rhythm (The 10-3-2-1-0 Rule) 40:01 Cognitive Behavioral Therapy for Insomnia (CBT-I) 42:08 Pillar 4: Chronic Stress vs. Your Nervous System 45:45 The Low-Hanging Fruit to Start Healing Today Relevant papers: - Cifuentes et al., 2024. Low-Grade Chronic Inflammation: a Shared Mechanism for Chronic Diseases. Physiology, 40: pp. 4-25; https://doi.org/10.1152/physiol.00021.2024 - Baylis et al. 2013. Understanding how we age: insights into inflammaging. Longevity & Healthspan, 2: Article 8; https://doi.org/10.1186/2046-2395-2-8 https://www.youtube-nocookie.com/embed/Qd3PZHnf53M 2909 2025-05-30T22:00:34.000Z 2026-10-22T19:54:19.234Z https://longevityharbor.com/de/watch/Qd3PZHnf53M How to Heal from Chronic Inflammation with Len De Nys | AFP 41 https://i.ytimg.com/vi/Qd3PZHnf53M/hqdefault.jpg Struggling with fatigue, brain fog, or joint pain? You might be battling chronic inflammation. Join Jeroen Schreel and Len De Nys, a postdoctoral researcher at Vrije Universiteit Brussel, as they uncover how to heal from chronic inflammation and prevent the root causes of modern chronic diseases. Len shares his personal story of reversing severe back pain and brain fog through an anti-inflammatory lifestyle, breaking down the phenomenon of "inflammaging" (how aging drives inflammation), how to test your body for chronic inflammation using CRP markers, and how to use lifestyle as a medicine (nutrition, exercise, sleep, and stress management) to protect your DNA and live longer. 00:00 Intro 00:41 Ad 01:50 Meet Len De Nys & The Naked Mole Rat Longevity Secret 03:32 Acute vs. Chronic Inflammation Explained 05:11 What is Inflammaging? (The Hallmarks of Aging) 07:15 Len’s Personal Story: Curing Back Pain & Brain Fog 10:46 How to Diagnose Chronic Inflammation (CRP Tests & Symptoms) 13:19 The Top 5 Killer Diseases Driven by Inflammation 15:30 Genetics vs. Epigenetics: What Pulls the Trigger? 17:05 Pillar 1: Anti-Inflammatory Nutrition & Foods to Avoid 21:35 Time-Restricted Eating & Intermittent Fasting benefits 23:40 Omega-3 Fats & Vegan Algae Alternatives 25:50 Pillar 2: How Exercise Trains Your Immune System 28:04 How Much Cardio & Power Training Do You Need? 31:12 The Danger of Under-Resting & Overtraining 33:14 Pillar 3: How Poor Sleep Destroys Your Immune System 35:31 How to Reset Your Circadian Rhythm (The 10-3-2-1-0 Rule) 40:01 Cognitive Behavioral Therapy for Insomnia (CBT-I) 42:08 Pillar 4: Chronic Stress vs. Your Nervous System 45:45 The Low-Hanging Fruit to Start Healing Today Relevant papers: - Cifuentes et al., 2024. Low-Grade Chronic Inflammation: a Shared Mechanism for Chronic Diseases. Physiology, 40: pp. 4-25; https://doi.org/10.1152/physiol.00021.2024 - Baylis et al. 2013. Understanding how we age: insights into inflammaging. Longevity & Healthspan, 2: Article 8; https://doi.org/10.1186/2046-2395-2-8 https://www.youtube-nocookie.com/embed/Qd3PZHnf53M 2909 2025-05-30T22:00:34.000Z 2026-10-22T19:54:19.234Z https://longevityharbor.com/en/watch/Qm6OzagByjA Video description: epigenetic clocks, a claimed 'glitch' and a corrective plan https://i.ytimg.com/vi/Qm6OzagByjA/hqdefault.jpg The description says the video explains epigenetic clocks as a cellular-level measure of aging speed, discusses a 'glitch in the clock', and offers a corrective action plan; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/Qm6OzagByjA 463 2026-07-11T14:00:21.000Z 2026-10-22T23:35:22.128Z https://longevityharbor.com/de/watch/Qm6OzagByjA Videobeschreibung: epigenetische Uhren, ein angeblicher „Glitch“ und ein Korrekturplan https://i.ytimg.com/vi/Qm6OzagByjA/hqdefault.jpg Laut Beschreibung erklärt das Video epigenetische Uhren als Messgröße des Alterns auf Zellebene, behandelt einen „Glitch in der Uhr“ und bietet einen konkreten Korrekturplan; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/Qm6OzagByjA 463 2026-07-11T14:00:21.000Z 2026-10-22T23:35:22.128Z https://longevityharbor.com/en/watch/QmAhnQT7BVI EP 050 Industry Insights - AI in Longevity Research https://i.ytimg.com/vi/QmAhnQT7BVI/hqdefault.jpg EPISODE 050: "AI in Longevity Research" ARTIFICIAL INTELLIGENCE | Longevity Science | Anti-Aging Medicine | Pharmaceutical Manufacturing | Healthspan Extension Discover how artificial intelligence is revolutionizing longevity research and creating unprecedented demand for pharmaceutical manufacturing capacity. This episode explores the convergence of AI and aging science—from drug discovery that's 70% successful (compared to single-digit success rates in traditional methods) to the first FDA-approved dog longevity trials paving the way for human therapies. Learn why extending healthy human lifespan by just one year could add $38 trillion to the global economy. KEY TOPICS COVERED: The Science of Aging The 12 hallmarks of aging: cellular senescence, mitochondrial dysfunction, telomere shortening Lifespan vs healthspan: adding life to years, not just years to life Biological age vs chronological age measured with AI-powered aging clocks Polypharmacology: targeting multiple aging pathways simultaneously Loyal's STAY study with 1,300+ dogs testing longevity drugs IGF-1 targeting for metabolic aging in large breeds AI & Machine Learning Breakthroughs Multi-omics analysis integrating genomics, proteomics, microbiome, and metabolome data Generative AI designing novel molecules in 46 days (Insilico Medicine) 70% success rate in AI-identified anti-aging compounds (Scripps Research, May 2025) In-silico modeling and digital twins for virtual clinical trials Drug repurposing: discovering hidden longevity benefits in existing medications Current Clinical Breakthroughs GLP-1 revolution: Ozempic, Wegovy, Mounjaro showing unexpected longevity benefits Metformin and rapamycin in clinical trials as anti-aging drugs Cellular reprogramming: reversing biological age at the cellular level NAD+ boosters and senolytic drugs clearing zombie cells FDA approval pathway for dog longevity drugs (LOY-002) INS018_055: AI-designed drug showing activity against six aging mechanisms Manufacturing Revolution & Scalability Cloud-based Manu https://www.youtube-nocookie.com/embed/QmAhnQT7BVI 2173 2025-09-19T14:27:50.000Z 2026-10-22T19:04:37.669Z https://longevityharbor.com/de/watch/QmAhnQT7BVI EP 050 Industry Insights - AI in Longevity Research https://i.ytimg.com/vi/QmAhnQT7BVI/hqdefault.jpg EPISODE 050: "AI in Longevity Research" ARTIFICIAL INTELLIGENCE | Longevity Science | Anti-Aging Medicine | Pharmaceutical Manufacturing | Healthspan Extension Discover how artificial intelligence is revolutionizing longevity research and creating unprecedented demand for pharmaceutical manufacturing capacity. This episode explores the convergence of AI and aging science—from drug discovery that's 70% successful (compared to single-digit success rates in traditional methods) to the first FDA-approved dog longevity trials paving the way for human therapies. Learn why extending healthy human lifespan by just one year could add $38 trillion to the global economy. KEY TOPICS COVERED: The Science of Aging The 12 hallmarks of aging: cellular senescence, mitochondrial dysfunction, telomere shortening Lifespan vs healthspan: adding life to years, not just years to life Biological age vs chronological age measured with AI-powered aging clocks Polypharmacology: targeting multiple aging pathways simultaneously Loyal's STAY study with 1,300+ dogs testing longevity drugs IGF-1 targeting for metabolic aging in large breeds AI & Machine Learning Breakthroughs Multi-omics analysis integrating genomics, proteomics, microbiome, and metabolome data Generative AI designing novel molecules in 46 days (Insilico Medicine) 70% success rate in AI-identified anti-aging compounds (Scripps Research, May 2025) In-silico modeling and digital twins for virtual clinical trials Drug repurposing: discovering hidden longevity benefits in existing medications Current Clinical Breakthroughs GLP-1 revolution: Ozempic, Wegovy, Mounjaro showing unexpected longevity benefits Metformin and rapamycin in clinical trials as anti-aging drugs Cellular reprogramming: reversing biological age at the cellular level NAD+ boosters and senolytic drugs clearing zombie cells FDA approval pathway for dog longevity drugs (LOY-002) INS018_055: AI-designed drug showing activity against six aging mechanisms Manufacturing Revolution & Scalability Cloud-based Manu https://www.youtube-nocookie.com/embed/QmAhnQT7BVI 2173 2025-09-19T14:27:50.000Z 2026-10-22T19:04:37.669Z https://longevityharbor.com/en/watch/QsYT5CcRJ90 SenCat: A Multi-omic Atlas for Decoding Human Cell Senescence https://i.ytimg.com/vi/QsYT5CcRJ90/hqdefault.jpg DOI: 10.1016/j.molcel.2026.05.017 Key-words: SenCat, cellular senescence, multi-omics, transcriptomics, proteomics, machine learning, primary human cells, RNA-seq, single-nucleus RNA sequencing, mass spectrometry, doxorubicin, physiological aging, tissue repair, metabolic reprogramming, biomarker signatures, p53 pathway, NF-κB, epithelial-to-mesenchymal transition, apoptosis, hypoxia, in vivo senescence, senescence scoring, AUCell, fibroblasts, SenNet. https://www.youtube-nocookie.com/embed/QsYT5CcRJ90 448 2026-06-15T05:03:28.000Z 2026-10-22T18:43:13.484Z https://longevityharbor.com/de/watch/QsYT5CcRJ90 SenCat: A Multi-omic Atlas for Decoding Human Cell Senescence https://i.ytimg.com/vi/QsYT5CcRJ90/hqdefault.jpg DOI: 10.1016/j.molcel.2026.05.017 Key-words: SenCat, cellular senescence, multi-omics, transcriptomics, proteomics, machine learning, primary human cells, RNA-seq, single-nucleus RNA sequencing, mass spectrometry, doxorubicin, physiological aging, tissue repair, metabolic reprogramming, biomarker signatures, p53 pathway, NF-κB, epithelial-to-mesenchymal transition, apoptosis, hypoxia, in vivo senescence, senescence scoring, AUCell, fibroblasts, SenNet. https://www.youtube-nocookie.com/embed/QsYT5CcRJ90 448 2026-06-15T05:03:28.000Z 2026-10-22T18:43:13.484Z https://longevityharbor.com/en/watch/QtZVQuzMWLg Video Description: Four Muscle Groups for Standing Up After 60 https://i.ytimg.com/vi/QtZVQuzMWLg/hqdefault.jpg A video description names four muscle groups — quadriceps, glutes, core and calves — as targets for strength exercises to make standing up from a chair easier with age, and lists gentle starter exercises. No study or data is presented. https://www.youtube-nocookie.com/embed/QtZVQuzMWLg 95 2026-10-14T23:47:58.000Z 2026-10-22T19:55:50.388Z https://longevityharbor.com/de/watch/QtZVQuzMWLg Videobeschreibung: Vier Muskelgruppen fürs Aufstehen nach 60 https://i.ytimg.com/vi/QtZVQuzMWLg/hqdefault.jpg Eine Videobeschreibung nennt vier Muskelgruppen — Quadrizeps, Gesäß, Rumpf und Waden — als Ziele für Kraftübungen, um das Aufstehen vom Stuhl im Alter zu erleichtern, und listet sanfte Einstiegsübungen. Eine Studie oder Daten werden nicht vorgestellt. https://www.youtube-nocookie.com/embed/QtZVQuzMWLg 95 2026-10-14T23:47:58.000Z 2026-10-22T19:55:50.388Z https://longevityharbor.com/en/watch/R09pGCLT9jQ Zombie Cells: The Anti-Aging Breakthrough Explained! https://i.ytimg.com/vi/R09pGCLT9jQ/hqdefault.jpg Discover the fascinating world of “zombie cells”—senescent cells that accumulate as we age and contribute to chronic diseases. In this doodle-style science video, we break down the latest anti-aging research and show how senolytic drugs and new treatments are revolutionizing longevity medicine. Learn how scientists are targeting senescent cells to boost health, rejuvenate tissues, and fight age-related decline. Perfect for anyone curious about human biology, aging, and the future of medicine. Like, subscribe, and share if you love science explained with doodles! https://www.youtube-nocookie.com/embed/R09pGCLT9jQ 332 2025-11-16T16:58:15.000Z 2026-10-22T19:43:47.828Z https://longevityharbor.com/de/watch/R09pGCLT9jQ Zombie Cells: The Anti-Aging Breakthrough Explained! https://i.ytimg.com/vi/R09pGCLT9jQ/hqdefault.jpg Discover the fascinating world of “zombie cells”—senescent cells that accumulate as we age and contribute to chronic diseases. In this doodle-style science video, we break down the latest anti-aging research and show how senolytic drugs and new treatments are revolutionizing longevity medicine. Learn how scientists are targeting senescent cells to boost health, rejuvenate tissues, and fight age-related decline. Perfect for anyone curious about human biology, aging, and the future of medicine. Like, subscribe, and share if you love science explained with doodles! https://www.youtube-nocookie.com/embed/R09pGCLT9jQ 332 2025-11-16T16:58:15.000Z 2026-10-22T19:43:47.828Z https://longevityharbor.com/en/watch/R0Gd6R2GCxY Proposed triple therapy targets senescence-driven ferroptosis resistance in pancreatic cancer https://i.ytimg.com/vi/R0Gd6R2GCxY/hqdefault.jpg The described article reports that gemcitabine-induced senescence stiffens the pancreatic tumor environment and protects cancer cells from ferroptosis; the authors propose a triple combination to restore drug sensitivity. https://www.youtube-nocookie.com/embed/R0Gd6R2GCxY 1200 2026-09-17T13:28:44.000Z 2026-10-22T22:09:54.126Z https://longevityharbor.com/de/watch/R0Gd6R2GCxY Vorgeschlagene Dreifachtherapie gegen seneszenzbedingte Ferroptose-Resistenz bei Bauchspeicheldrüsen https://i.ytimg.com/vi/R0Gd6R2GCxY/hqdefault.jpg Der beschriebene Artikel berichtet, dass durch Gemcitabin ausgelöste Seneszenz die Umgebung des Pankreastumors versteift und Krebszellen vor Ferroptose schützt; die Autoren schlagen eine Dreifachkombination vor, um die Arzneimittelempfindlichkeit wiederherzustellen. https://www.youtube-nocookie.com/embed/R0Gd6R2GCxY 1200 2026-09-17T13:28:44.000Z 2026-10-22T22:09:54.126Z https://longevityharbor.com/en/watch/R4fiX7LTuR4 Talk listing: intermittent fasting, cognitive performance and BDNF as a proposed target https://i.ytimg.com/vi/R4fiX7LTuR4/hqdefault.jpg This description announces a talk by Dr Karin Seidler on intermittent fasting and cognitive performance, framed as targeting BDNF as a potential strategy to optimise brain health. It gives no results, data or study details. https://www.youtube-nocookie.com/embed/R4fiX7LTuR4 1167 2025-12-15T11:59:06.000Z 2026-10-23T03:16:49.944Z https://longevityharbor.com/de/watch/R4fiX7LTuR4 Vortragsankündigung: Intervallfasten, kognitive Leistung und BDNF als vorgeschlagenes Ziel https://i.ytimg.com/vi/R4fiX7LTuR4/hqdefault.jpg Diese Beschreibung kündigt einen Vortrag von Dr. Karin Seidler über Intervallfasten und kognitive Leistung an, gerahmt als mögliche Strategie über BDNF zur Förderung der Hirngesundheit. Ergebnisse, Daten oder Studiendetails nennt sie nicht. https://www.youtube-nocookie.com/embed/R4fiX7LTuR4 1167 2025-12-15T11:59:06.000Z 2026-10-23T03:16:49.944Z https://longevityharbor.com/en/watch/R7vVs50Y7N0 Cellular Senescence and Senolytics in Aging and Diseases https://i.ytimg.com/vi/R7vVs50Y7N0/hqdefault.jpg Join us for a BioTalk webinar on cellular senescence, a hallmark of aging where cells permanently exit the cell cycle due to damage and stress. Cellular senescence, a hallmark of aging, involves the stable exit from the cell cycle in response to cellular damage and stress. Senescent cells (SnCs) often develop a pathogenic senescence-associated secretory phenotype (SASP) that promotes secondary senescence and disrupts tissue homeostasis, impairing tissue repair and regeneration. Transgenic mouse models with the capability for genetic ablation of SnCs have demonstrated their crucial role in driving aging and related diseases. Consequently, senotherapeutics have been developed to either pharmacologically eliminate SnCs (senolytics) or suppress the SASP and other senescence markers (senomorphics). Extensive preclinical studies and initial clinical trials have shown the potential benefits of senotherapeutics, leading to multiple ongoing clinical trials. In conclusion, targeting cellular senescence presents a promising therapeutic strategy for slowing aging and treating age-related diseases. This webinar is made in collaboration with GenoBioTx --- Speaker Yi Zhu - Assistant Professor, Mayo Clinic Dr. Yi Zhu earned her BS from Beijing Normal University, followed by a PhD from the University of Michigan. She completed her postdoctoral training under the mentorship of Dr. James Kirkland at the Mayo Clinic, where she later joined the faculty in the Department of Physiology and Biomedical Engineering. Now an assistant professor at Mayo Clinic, Dr. Zhu is renowned for her groundbreaking work on cellular senescence. Her research primarily focuses on how senescent cells drive age-related diseases and neurological disorders. Among her significant achievements is the discovery of the first generation of senolytics in 2015, which has shown great promise in preclinical trials for mitigating age-associated dysfunction. Currently, Dr. Zhu’s research targets senescent glial cells and explores the role of peripheral senescent c https://www.youtube-nocookie.com/embed/R7vVs50Y7N0 3278 2024-09-25T17:18:01.000Z 2026-10-22T18:43:13.466Z https://longevityharbor.com/de/watch/R7vVs50Y7N0 Cellular Senescence and Senolytics in Aging and Diseases https://i.ytimg.com/vi/R7vVs50Y7N0/hqdefault.jpg Join us for a BioTalk webinar on cellular senescence, a hallmark of aging where cells permanently exit the cell cycle due to damage and stress. Cellular senescence, a hallmark of aging, involves the stable exit from the cell cycle in response to cellular damage and stress. Senescent cells (SnCs) often develop a pathogenic senescence-associated secretory phenotype (SASP) that promotes secondary senescence and disrupts tissue homeostasis, impairing tissue repair and regeneration. Transgenic mouse models with the capability for genetic ablation of SnCs have demonstrated their crucial role in driving aging and related diseases. Consequently, senotherapeutics have been developed to either pharmacologically eliminate SnCs (senolytics) or suppress the SASP and other senescence markers (senomorphics). Extensive preclinical studies and initial clinical trials have shown the potential benefits of senotherapeutics, leading to multiple ongoing clinical trials. In conclusion, targeting cellular senescence presents a promising therapeutic strategy for slowing aging and treating age-related diseases. This webinar is made in collaboration with GenoBioTx --- Speaker Yi Zhu - Assistant Professor, Mayo Clinic Dr. Yi Zhu earned her BS from Beijing Normal University, followed by a PhD from the University of Michigan. She completed her postdoctoral training under the mentorship of Dr. James Kirkland at the Mayo Clinic, where she later joined the faculty in the Department of Physiology and Biomedical Engineering. Now an assistant professor at Mayo Clinic, Dr. Zhu is renowned for her groundbreaking work on cellular senescence. Her research primarily focuses on how senescent cells drive age-related diseases and neurological disorders. Among her significant achievements is the discovery of the first generation of senolytics in 2015, which has shown great promise in preclinical trials for mitigating age-associated dysfunction. Currently, Dr. Zhu’s research targets senescent glial cells and explores the role of peripheral senescent c https://www.youtube-nocookie.com/embed/R7vVs50Y7N0 3278 2024-09-25T17:18:01.000Z 2026-10-22T18:43:13.466Z https://longevityharbor.com/en/watch/R8274sPHdjY Short video description claims muscle is the best defense against aging https://i.ytimg.com/vi/R8274sPHdjY/hqdefault.jpg The description of this short video states that muscle is your best defense against aging, but gives no study, data or explanation. It also advertises a fitness program and notes the content is general information, not medical advice. https://www.youtube-nocookie.com/embed/R8274sPHdjY 97 2026-02-13T03:08:34.000Z 2026-10-23T02:35:31.148Z https://longevityharbor.com/de/watch/R8274sPHdjY Kurzbeschreibung behauptet, Muskeln seien der beste Schutz gegen das Altern https://i.ytimg.com/vi/R8274sPHdjY/hqdefault.jpg Die Beschreibung dieses Kurzvideos behauptet, Muskeln seien der beste Schutz gegen das Altern, nennt aber keine Studie, Daten oder Erklärung. Sie bewirbt zudem ein Fitnessprogramm und weist darauf hin, dass die Inhalte allgemeine Informationen und kein medizinischer Rat sind. https://www.youtube-nocookie.com/embed/R8274sPHdjY 97 2026-02-13T03:08:34.000Z 2026-10-23T02:35:31.148Z https://longevityharbor.com/en/watch/RBilnATdlGw Senolytic Therapies: A Global Anti-Aging Research Update https://i.ytimg.com/vi/RBilnATdlGw/hqdefault.jpg The provided text offers a comprehensive overview of global advancements in senolytic therapies, highlighting their rapid progression from preclinical research to human trials. It details diverse clinical studies across the United States, Europe, and Asia-Pacific, targeting conditions like frailty, cognitive decline, and organ rejuvenation. The text also explores emerging mechanisms and technologies, such as novel peptides, PROTACs, and even "aging vaccines," alongside regulatory developments from bodies like the FDA and EMA. Finally, it outlines the promising future outlook for senolytics, projecting their widespread use in preventive aging care, while also acknowledging current feasibility and safety challenges. #research #antianging #senolytics #update https://www.youtube-nocookie.com/embed/RBilnATdlGw 1122 2025-06-22T06:04:16.000Z 2026-10-22T18:43:13.622Z https://longevityharbor.com/de/watch/RBilnATdlGw Senolytic Therapies: A Global Anti-Aging Research Update https://i.ytimg.com/vi/RBilnATdlGw/hqdefault.jpg The provided text offers a comprehensive overview of global advancements in senolytic therapies, highlighting their rapid progression from preclinical research to human trials. It details diverse clinical studies across the United States, Europe, and Asia-Pacific, targeting conditions like frailty, cognitive decline, and organ rejuvenation. The text also explores emerging mechanisms and technologies, such as novel peptides, PROTACs, and even "aging vaccines," alongside regulatory developments from bodies like the FDA and EMA. Finally, it outlines the promising future outlook for senolytics, projecting their widespread use in preventive aging care, while also acknowledging current feasibility and safety challenges. #research #antianging #senolytics #update https://www.youtube-nocookie.com/embed/RBilnATdlGw 1122 2025-06-22T06:04:16.000Z 2026-10-22T18:43:13.622Z https://longevityharbor.com/en/watch/RELPBtM0i1M Video description: five exercise types proposed for people over 70 https://i.ytimg.com/vi/RELPBtM0i1M/hqdefault.jpg The description presents five exercise types for people over 70: strength training, balance training, brisk walking, mobility work and getting up from the floor. It links them to muscle, bone, falls, heart, brain and joints, but reports no study results. https://www.youtube-nocookie.com/embed/RELPBtM0i1M 1092 2026-07-30T08:23:18.000Z 2026-10-22T23:22:10.968Z https://longevityharbor.com/de/watch/RELPBtM0i1M Videobeschreibung: fünf Übungsarten für Menschen über 70 vorgeschlagen https://i.ytimg.com/vi/RELPBtM0i1M/hqdefault.jpg Die Beschreibung stellt fünf Übungsarten für Menschen über 70 vor: Krafttraining, Gleichgewichtstraining, zügiges Gehen, Mobilitätsübungen und das Aufstehen vom Boden. Sie verknüpft sie mit Muskeln, Knochen, Stürzen, Herz, Gehirn und Gelenken, nennt aber keine Studienergebnisse. https://www.youtube-nocookie.com/embed/RELPBtM0i1M 1092 2026-07-30T08:23:18.000Z 2026-10-22T23:22:10.968Z https://longevityharbor.com/en/watch/REfhd5k5n0o Is rapamycin an effective longevity drug? https://i.ytimg.com/vi/REfhd5k5n0o/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/Io5xV9rtbm4?si=YbHDA2iR02950c9u Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 300 ‒ Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, & more. In this clip, they discuss: - What makes rapamycin a promising longevity drug? - What evidence do we still need for the efficacy of rapamycin? - Why Peter doesn't think everyone should blindly take rapamycin even though he takes it - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or dela https://www.youtube-nocookie.com/embed/REfhd5k5n0o 528 2024-05-12T16:00:16.000Z 2026-10-22T18:43:07.223Z https://longevityharbor.com/de/watch/REfhd5k5n0o Is rapamycin an effective longevity drug? https://i.ytimg.com/vi/REfhd5k5n0o/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/Io5xV9rtbm4?si=YbHDA2iR02950c9u Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 300 ‒ Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, & more. In this clip, they discuss: - What makes rapamycin a promising longevity drug? - What evidence do we still need for the efficacy of rapamycin? - Why Peter doesn't think everyone should blindly take rapamycin even though he takes it - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or dela https://www.youtube-nocookie.com/embed/REfhd5k5n0o 528 2024-05-12T16:00:16.000Z 2026-10-22T18:43:07.223Z https://longevityharbor.com/en/watch/RFdt4mCR2s0 Circadian Code for Healthy Lifespan by Dr. Satchidananda Panda https://i.ytimg.com/vi/RFdt4mCR2s0/hqdefault.jpg In this talk, Dr. Satchidananda Panda, Professor, Salk Institute, California, USA, explains how aligning our daily routines with our body’s internal clock can profoundly impact our health, aging, and longevity. Associate Professor Emeritus To thrive within nature day-night cycle, our genetic makeup is designed to orchestrate the rise and fall of nearly every gene in our genome at specific times. This rhythmic gene expression is vital for maintaining overall health and vitality. In our modern world, circadian rhythms are frequently disrupted, elevating risks of various chronic diseases. An understanding of circadian rhythm principles can lead to lifestyle interventions aimed at preventing, managing, and even reversing chronic diseases. One such pragmatic approach is time-restricted feeding/eating (TRF/TRE), a form of intermittent fasting that confines food intake to a consistent 8-10-hour daily window. Laboratory studies have demonstrated that TRF sustains the circadian rhythm. TRF can be a preventive or therapeutic measure for several chronic conditions, including obesity, diabetes, liver and kidney diseases, various cancers, and neurodegenerative diseases. Furthermore, TRF, when combined with a healthy diet, can enhance or preserve muscle mass in older animals and extend lifespan. Human studies on TRF are beginning to replicate the key benefits observed in laboratory animals. Beyond food timing, the timing and quality of light exposure also play a crucial role in influencing our sleep and circadian rhythm. Optimal light exposure has been linked to reduced depression, improved mood, enhanced nighttime sleep, and even accelerated recovery in hospitalized patients. In summary, insights from circadian rhythm science are unveiling new lifestyle choices that have the potential to be implemented on a population scale. These interventions aim to sustain both physical and mental health throughout the human lifespan. More: Longevity India: https://www.longevity.iisc.ac.in/ LinkedIn: https://www.linkedin.com/company/l https://www.youtube-nocookie.com/embed/RFdt4mCR2s0 1377 2025-08-04T06:00:55.000Z 2026-10-22T19:21:25.259Z https://longevityharbor.com/de/watch/RFdt4mCR2s0 Circadian Code for Healthy Lifespan by Dr. Satchidananda Panda https://i.ytimg.com/vi/RFdt4mCR2s0/hqdefault.jpg In this talk, Dr. Satchidananda Panda, Professor, Salk Institute, California, USA, explains how aligning our daily routines with our body’s internal clock can profoundly impact our health, aging, and longevity. Associate Professor Emeritus To thrive within nature day-night cycle, our genetic makeup is designed to orchestrate the rise and fall of nearly every gene in our genome at specific times. This rhythmic gene expression is vital for maintaining overall health and vitality. In our modern world, circadian rhythms are frequently disrupted, elevating risks of various chronic diseases. An understanding of circadian rhythm principles can lead to lifestyle interventions aimed at preventing, managing, and even reversing chronic diseases. One such pragmatic approach is time-restricted feeding/eating (TRF/TRE), a form of intermittent fasting that confines food intake to a consistent 8-10-hour daily window. Laboratory studies have demonstrated that TRF sustains the circadian rhythm. TRF can be a preventive or therapeutic measure for several chronic conditions, including obesity, diabetes, liver and kidney diseases, various cancers, and neurodegenerative diseases. Furthermore, TRF, when combined with a healthy diet, can enhance or preserve muscle mass in older animals and extend lifespan. Human studies on TRF are beginning to replicate the key benefits observed in laboratory animals. Beyond food timing, the timing and quality of light exposure also play a crucial role in influencing our sleep and circadian rhythm. Optimal light exposure has been linked to reduced depression, improved mood, enhanced nighttime sleep, and even accelerated recovery in hospitalized patients. In summary, insights from circadian rhythm science are unveiling new lifestyle choices that have the potential to be implemented on a population scale. These interventions aim to sustain both physical and mental health throughout the human lifespan. More: Longevity India: https://www.longevity.iisc.ac.in/ LinkedIn: https://www.linkedin.com/company/l https://www.youtube-nocookie.com/embed/RFdt4mCR2s0 1377 2025-08-04T06:00:55.000Z 2026-10-22T19:21:25.259Z https://longevityharbor.com/en/watch/RIfHSjPGZBM NAD+ levels in humans: blood versus tissue, aging, exercise and NMN/NR https://i.ytimg.com/vi/RIfHSjPGZBM/hqdefault.jpg The video description says human NAD+ findings are more complicated than a simple aging story: blood and tissue measurements can differ, and a blood NAD+ result is not a whole-body health score. https://www.youtube-nocookie.com/embed/RIfHSjPGZBM 328 2026-08-25T10:18:08.000Z 2026-10-22T22:46:57.032Z https://longevityharbor.com/de/watch/RIfHSjPGZBM NAD+-Spiegel beim Menschen: Blut versus Gewebe, Altern, Bewegung und NMN/NR https://i.ytimg.com/vi/RIfHSjPGZBM/hqdefault.jpg Die Videobeschreibung sagt, menschliche NAD+-Befunde seien komplizierter als eine einfache Altersgeschichte: Blut- und Gewebemessungen können abweichen, und ein Blut-NAD+-Ergebnis ist kein Ganzkörper-Gesundheitswert. https://www.youtube-nocookie.com/embed/RIfHSjPGZBM 328 2026-08-25T10:18:08.000Z 2026-10-22T22:46:57.032Z https://longevityharbor.com/en/watch/RRJgGNHYpfM Sleepy Science video description: 100 longevity facts for bedtime https://i.ytimg.com/vi/RRJgGNHYpfM/hqdefault.jpg The description says this bedtime video presents one hundred longevity facts, from telomeres and mitochondria to Blue Zones and circadian rhythms, in a calm voice with no adverts. https://www.youtube-nocookie.com/embed/RRJgGNHYpfM 8581 2026-05-27T19:00:05.000Z 2026-10-23T00:19:09.644Z https://longevityharbor.com/de/watch/RRJgGNHYpfM Sleepy-Science-Beschreibung: 100 Langlebigkeitsfakten zum Einschlafen https://i.ytimg.com/vi/RRJgGNHYpfM/hqdefault.jpg Laut Beschreibung präsentiert dieses Einschlafvideo einhundert Fakten zur Langlebigkeit – von Telomeren und Mitochondrien bis zu Blue Zones und circadianen Rhythmen – in ruhiger Stimme und ohne Werbung. https://www.youtube-nocookie.com/embed/RRJgGNHYpfM 8581 2026-05-27T19:00:05.000Z 2026-10-23T00:19:09.644Z https://longevityharbor.com/en/watch/RRcx1njwrPI Beat Zombie Cells: Tips for Healthy Aging! #healthyaging https://i.ytimg.com/vi/RRcx1njwrPI/hqdefault.jpg 🧟‍♂️ *Zombie cells?* Yep, they’re real—and they might be silently accelerating aging in your body. This video dives into the science of **cellular senescence**—what it is, why it matters, and how lifestyle choices can help you fight back. Senescent cells (aka zombie cells) stop functioning properly but refuse to die. Instead, they linger, releasing toxic molecules that damage nearby healthy cells and drive **chronic inflammation**, also known as **inflammaging**. You’ll learn: ✅ What causes zombie cells to form ✅ How they contribute to diseases like diabetes, cardiovascular issues ✅ How **exercise**, **diet**, **sleep**, and **gut health** can help clear them out ✅ Which foods and habits have *senolytic* (zombie cell-killing) effects Aging is inevitable—but how you age is something you *can* influence. 💪 🔔 If this video helps you understand the aging process and how to take control of your health, don’t forget to **like** and **subscribe** for more science-backed content on healthy aging. #ZombieCells #CellularSenescence #HealthyAging #Inflammaging #Longevity #Senolytics #ScienceExplained https://www.youtube-nocookie.com/embed/RRcx1njwrPI 178 2025-04-19T02:17:21.000Z 2026-10-22T19:21:21.839Z https://longevityharbor.com/de/watch/RRcx1njwrPI Beat Zombie Cells: Tips for Healthy Aging! #healthyaging https://i.ytimg.com/vi/RRcx1njwrPI/hqdefault.jpg 🧟‍♂️ *Zombie cells?* Yep, they’re real—and they might be silently accelerating aging in your body. This video dives into the science of **cellular senescence**—what it is, why it matters, and how lifestyle choices can help you fight back. Senescent cells (aka zombie cells) stop functioning properly but refuse to die. Instead, they linger, releasing toxic molecules that damage nearby healthy cells and drive **chronic inflammation**, also known as **inflammaging**. You’ll learn: ✅ What causes zombie cells to form ✅ How they contribute to diseases like diabetes, cardiovascular issues ✅ How **exercise**, **diet**, **sleep**, and **gut health** can help clear them out ✅ Which foods and habits have *senolytic* (zombie cell-killing) effects Aging is inevitable—but how you age is something you *can* influence. 💪 🔔 If this video helps you understand the aging process and how to take control of your health, don’t forget to **like** and **subscribe** for more science-backed content on healthy aging. #ZombieCells #CellularSenescence #HealthyAging #Inflammaging #Longevity #Senolytics #ScienceExplained https://www.youtube-nocookie.com/embed/RRcx1njwrPI 178 2025-04-19T02:17:21.000Z 2026-10-22T19:21:21.839Z https://longevityharbor.com/en/watch/RcnVvxALz-k Using resistance training to prevent muscle loss from old age and inactivity | Luc van Loon https://i.ytimg.com/vi/RcnVvxALz-k/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/AVOKWvYJM-c Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 299 ‒ Protein: muscle protein synthesis optimization, quality sources, quantity needs, and the importance of resistance training with Luc van Loon, Ph.D. Luc is an internationally renowned expert in skeletal muscle metabolism. In this clip, they discuss: - How quickly you can lose muscle from inactivity and sickness - How long does it take to gain muscle back? - Why muscle fiber atrophy should be described as one of the hallmarks of aging - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for p https://www.youtube-nocookie.com/embed/RcnVvxALz-k 749 2024-05-03T16:00:32.000Z 2026-10-22T19:04:37.526Z https://longevityharbor.com/de/watch/RcnVvxALz-k Using resistance training to prevent muscle loss from old age and inactivity | Luc van Loon https://i.ytimg.com/vi/RcnVvxALz-k/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/AVOKWvYJM-c Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 299 ‒ Protein: muscle protein synthesis optimization, quality sources, quantity needs, and the importance of resistance training with Luc van Loon, Ph.D. Luc is an internationally renowned expert in skeletal muscle metabolism. In this clip, they discuss: - How quickly you can lose muscle from inactivity and sickness - How long does it take to gain muscle back? - Why muscle fiber atrophy should be described as one of the hallmarks of aging - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for p https://www.youtube-nocookie.com/embed/RcnVvxALz-k 749 2024-05-03T16:00:32.000Z 2026-10-22T19:04:37.526Z https://longevityharbor.com/en/watch/RfnJQGtgjlA Documentary description: fasting, nutrition and longevity, inspired by Valter Longo https://i.ytimg.com/vi/RfnJQGtgjlA/hqdefault.jpg The description presents a documentary inspired by Valter Longo's books that explores how nutrition, fasting-mimicking protocols and lifestyle choices may influence longevity and long-term health beyond genetics. It names no study results. https://www.youtube-nocookie.com/embed/RfnJQGtgjlA 143 2026-04-24T22:00:26.000Z 2026-10-23T01:29:33.219Z https://longevityharbor.com/de/watch/RfnJQGtgjlA Dokumentarfilmbeschreibung: Fasten, Ernährung und Langlebigkeit nach Valter Longo https://i.ytimg.com/vi/RfnJQGtgjlA/hqdefault.jpg Die Beschreibung stellt einen Dokumentarfilm vor, inspiriert von Valter Longos Büchern, der untersucht, wie Ernährung, fastenimitierende Protokolle und Lebensstil die Langlebigkeit und langfristige Gesundheit über die Genetik hinaus beeinflussen könnten. Studienergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/RfnJQGtgjlA 143 2026-04-24T22:00:26.000Z 2026-10-23T01:29:33.219Z https://longevityharbor.com/en/watch/RgXoE49cdE0 Why does heart rate variability (HRV) decline with age? | Peter Attia and Joel Jamieson https://i.ytimg.com/vi/RgXoE49cdE0/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/3TClfAvj2-Q Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 305 - Heart rate variability: measure, interpret, & utilize HRV for training and health optimization with Joel Jamieson. Joel is a conditioning expert who developed Morpheus to give people a smarter way to build their conditioning regimen and improve their recovery. In this clip, they discuss: - What is it physiologically, at the cellular level, that is resulting in this profound reduction in HRV as we age? - How much do genetics influence HRV? - Why lack of resilience is a hallmark of aging - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content o https://www.youtube-nocookie.com/embed/RgXoE49cdE0 236 2024-06-14T16:00:24.000Z 2026-10-22T19:32:33.354Z https://longevityharbor.com/de/watch/RgXoE49cdE0 Why does heart rate variability (HRV) decline with age? | Peter Attia and Joel Jamieson https://i.ytimg.com/vi/RgXoE49cdE0/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/3TClfAvj2-Q Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 305 - Heart rate variability: measure, interpret, & utilize HRV for training and health optimization with Joel Jamieson. Joel is a conditioning expert who developed Morpheus to give people a smarter way to build their conditioning regimen and improve their recovery. In this clip, they discuss: - What is it physiologically, at the cellular level, that is resulting in this profound reduction in HRV as we age? - How much do genetics influence HRV? - Why lack of resilience is a hallmark of aging - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content o https://www.youtube-nocookie.com/embed/RgXoE49cdE0 236 2024-06-14T16:00:24.000Z 2026-10-22T19:32:33.354Z https://longevityharbor.com/en/watch/RgxHdevG2as The Gut Clock Connection: How Butyrate and Epigenetics Shape Your Daily Rhythms https://i.ytimg.com/vi/RgxHdevG2as/hqdefault.jpg I used to think fixing someone’s circadian rhythm was all about light. Get morning sunlight. Avoid screens at night. Simple in theory. But in practice, it didn’t always work. I saw clients doing everything right. Timing their meals. Going for walks. Winding down with no screens before bed. And still waking up tired, inflamed, out of sync. That’s what pushed me to look deeper. Not just when we sleep or eat, but what’s happening inside our gut that might be controlling those rhythms in the first place. That’s where butyrate came in. It’s a short chain fatty acid made when your gut microbes ferment fiber. But it doesn’t just stay in the gut. It travels, signals, and influences how genes behave in tissues like the liver, muscle, and intestines (dos Santos A. & Vasylyshyn A., 2025). Butyrate helps activate genes that run your biological clock, not by changing your DNA but by altering how your body reads it. That’s epigenetics (Caprara G. et al., 2025). Your gut can actually talk to your circadian rhythm. And it’s not abstract. It's measurable. Disruptions in your microbiota from antibiotics, poor diet, or even stress can misalign your internal clock and lead to metabolic issues, fatigue, or poor sleep (Cai Y. et al., 2023). The good news? It’s modifiable. Soluble fiber from fruits, veggies, and whole grains feeds the microbes that make butyrate. Exercise and meal timing amplify that effect (Cai Y. et al., 2023). If you’ve been doing all the “right” things and still feel off… Don’t just look at your schedule. Look at your gut. Want to learn more? My latest blog post breaks down how your gut shapes your body’s internal clock. https://www.youtube-nocookie.com/embed/RgxHdevG2as 106 2025-09-16T18:39:20.000Z 2026-10-22T18:54:03.194Z https://longevityharbor.com/de/watch/RgxHdevG2as The Gut Clock Connection: How Butyrate and Epigenetics Shape Your Daily Rhythms https://i.ytimg.com/vi/RgxHdevG2as/hqdefault.jpg I used to think fixing someone’s circadian rhythm was all about light. Get morning sunlight. Avoid screens at night. Simple in theory. But in practice, it didn’t always work. I saw clients doing everything right. Timing their meals. Going for walks. Winding down with no screens before bed. And still waking up tired, inflamed, out of sync. That’s what pushed me to look deeper. Not just when we sleep or eat, but what’s happening inside our gut that might be controlling those rhythms in the first place. That’s where butyrate came in. It’s a short chain fatty acid made when your gut microbes ferment fiber. But it doesn’t just stay in the gut. It travels, signals, and influences how genes behave in tissues like the liver, muscle, and intestines (dos Santos A. & Vasylyshyn A., 2025). Butyrate helps activate genes that run your biological clock, not by changing your DNA but by altering how your body reads it. That’s epigenetics (Caprara G. et al., 2025). Your gut can actually talk to your circadian rhythm. And it’s not abstract. It's measurable. Disruptions in your microbiota from antibiotics, poor diet, or even stress can misalign your internal clock and lead to metabolic issues, fatigue, or poor sleep (Cai Y. et al., 2023). The good news? It’s modifiable. Soluble fiber from fruits, veggies, and whole grains feeds the microbes that make butyrate. Exercise and meal timing amplify that effect (Cai Y. et al., 2023). If you’ve been doing all the “right” things and still feel off… Don’t just look at your schedule. Look at your gut. Want to learn more? My latest blog post breaks down how your gut shapes your body’s internal clock. https://www.youtube-nocookie.com/embed/RgxHdevG2as 106 2025-09-16T18:39:20.000Z 2026-10-22T18:54:03.194Z https://longevityharbor.com/en/watch/RiLQ6pBSQKc Cheek swabs, epigenetic clocks, and kids https://i.ytimg.com/vi/RiLQ6pBSQKc/hqdefault.jpg Cheek swabs are easy to collect, but the science behind them is anything but simple. In this episode, Dr. Sarah Merrill and Dr. Chaini Konwar discuss how the proportion of cells collected from cheek swabs — buccal epithelial cells — change with age and why this matters for pediatric epigenetics.  Learn how these changes impact biomarker accuracy, epigenetic clocks like PedBE, and our understanding of child development and health risks. For scientists and curious minds alike, the episode explores how cheek swabs — from infancy through adolescence — can help us better track, understand, and support children's health over time.  Learn more about topics discussed in this episode: Impact of age-related changes in buccal epithelial cells on pediatric epigenetic biomarker research (https://www.nature.com/articles/s41467-025-55909-8) , Nature Communications All episodes written and produced by the Research Communications team at BC Children's Hospital Research Institute (https://www.bcchr.ca/) . Theme music: "Life Is Beautiful" by Anastasia Kir https://www.youtube-nocookie.com/embed/RiLQ6pBSQKc 1780 2025-09-04T22:54:48.000Z 2026-10-22T18:32:06.812Z https://longevityharbor.com/de/watch/RiLQ6pBSQKc Cheek swabs, epigenetic clocks, and kids https://i.ytimg.com/vi/RiLQ6pBSQKc/hqdefault.jpg Cheek swabs are easy to collect, but the science behind them is anything but simple. In this episode, Dr. Sarah Merrill and Dr. Chaini Konwar discuss how the proportion of cells collected from cheek swabs — buccal epithelial cells — change with age and why this matters for pediatric epigenetics.  Learn how these changes impact biomarker accuracy, epigenetic clocks like PedBE, and our understanding of child development and health risks. For scientists and curious minds alike, the episode explores how cheek swabs — from infancy through adolescence — can help us better track, understand, and support children's health over time.  Learn more about topics discussed in this episode: Impact of age-related changes in buccal epithelial cells on pediatric epigenetic biomarker research (https://www.nature.com/articles/s41467-025-55909-8) , Nature Communications All episodes written and produced by the Research Communications team at BC Children's Hospital Research Institute (https://www.bcchr.ca/) . Theme music: "Life Is Beautiful" by Anastasia Kir https://www.youtube-nocookie.com/embed/RiLQ6pBSQKc 1780 2025-09-04T22:54:48.000Z 2026-10-22T18:32:06.812Z https://longevityharbor.com/en/watch/RkAC4vrv61g Video description on NMN, NAD⁺ and unproven anti-aging claims https://i.ytimg.com/vi/RkAC4vrv61g/hqdefault.jpg The description says early human trials suggest oral NMN can raise blood NAD⁺ and seems reasonably well tolerated short-term, but reversing aging, preventing disease or extending human lifespan is not established. https://www.youtube-nocookie.com/embed/RkAC4vrv61g 238 2026-09-04T04:00:22.000Z 2026-10-22T22:30:24.488Z https://longevityharbor.com/de/watch/RkAC4vrv61g Videobeschreibung zu NMN, NAD⁺ und unbelegten Anti-Aging-Versprechen https://i.ytimg.com/vi/RkAC4vrv61g/hqdefault.jpg Laut Beschreibung deuten frühe Humanstudien darauf hin, dass orales NMN den NAD⁺-Spiegel im Blut erhöhen kann und kurzfristig vertretbar vertragen zu werden scheint; Altern umzukehren, Krankheiten vorzubeugen oder die menschliche Lebensspanne zu verlängern ist jedoch nicht belegt. https://www.youtube-nocookie.com/embed/RkAC4vrv61g 238 2026-09-04T04:00:22.000Z 2026-10-22T22:30:24.488Z https://longevityharbor.com/en/watch/Rra9FJ2lURI STOP Aging and Look YOUNGER! https://i.ytimg.com/vi/Rra9FJ2lURI/hqdefault.jpg Is it possible to slow down aging? Find out how to look younger, live longer, and have fewer diseases in this quick video! Just so you know, my full line of high-quality supplements is available on Amazon — search Dr. Berg Supplements. 0:00 Introduction: How to slow down aging 0:35 Anti-aging secrets 1:30 NAD explained 2:25 Anti-aging tips 4:07 Check out my video on methylene blue! In this video, I’m going to tell you how to slow down aging so you can look younger and live longer. The mitochondria are the body's energy factory. The health and function of your mitochondria directly correlate to aging and longevity. The Krebs cycle is a process in your body that starts with food and ends with energy. It requires nutrients or cofactors to work properly. NAD is a vital nutrient involved in extracting energy from food to make ATP, and it’s critical for longevity and anti-aging. NAD prevents muscle loss, especially in cancer patients, and protects against radiation. As we age, NAD decreases. Researchers have found that CD38 depletes NAD, and mice with less CD38 tend to live longer. Here are 5 compounds that boost NAD to help slow aging: 1. Apigenin Parsley is the best source, but it’s also found in thyme, oregano, basil, and celery. 2. Anthoxanthin Consume blueberries and other blue, purple, or red foods such as elderberry, concord grapes, and purple potato. 3. Curcumin This is found in turmeric. 4. Quercetin The best source is onion, and the most is found in the outer part. You can also find quercetin in apple skin. 5. Methylene blue This was the first medical drug ever invented. It seems to be a good inhibitor of CD38, which can help boost NAD. Dr. Eric Berg DC Bio: Dr. Berg, age 59, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan and is the Director of Dr. Berg Nutritionals. He no longer practices but focuses on health education through social media. Follow Me On Social Media: YouTube: https://www.yout https://www.youtube-nocookie.com/embed/Rra9FJ2lURI 257 2024-06-05T12:00:27.000Z 2026-10-22T19:04:42.922Z https://longevityharbor.com/de/watch/Rra9FJ2lURI STOP Aging and Look YOUNGER! https://i.ytimg.com/vi/Rra9FJ2lURI/hqdefault.jpg Is it possible to slow down aging? Find out how to look younger, live longer, and have fewer diseases in this quick video! Just so you know, my full line of high-quality supplements is available on Amazon — search Dr. Berg Supplements. 0:00 Introduction: How to slow down aging 0:35 Anti-aging secrets 1:30 NAD explained 2:25 Anti-aging tips 4:07 Check out my video on methylene blue! In this video, I’m going to tell you how to slow down aging so you can look younger and live longer. The mitochondria are the body's energy factory. The health and function of your mitochondria directly correlate to aging and longevity. The Krebs cycle is a process in your body that starts with food and ends with energy. It requires nutrients or cofactors to work properly. NAD is a vital nutrient involved in extracting energy from food to make ATP, and it’s critical for longevity and anti-aging. NAD prevents muscle loss, especially in cancer patients, and protects against radiation. As we age, NAD decreases. Researchers have found that CD38 depletes NAD, and mice with less CD38 tend to live longer. Here are 5 compounds that boost NAD to help slow aging: 1. Apigenin Parsley is the best source, but it’s also found in thyme, oregano, basil, and celery. 2. Anthoxanthin Consume blueberries and other blue, purple, or red foods such as elderberry, concord grapes, and purple potato. 3. Curcumin This is found in turmeric. 4. Quercetin The best source is onion, and the most is found in the outer part. You can also find quercetin in apple skin. 5. Methylene blue This was the first medical drug ever invented. It seems to be a good inhibitor of CD38, which can help boost NAD. Dr. Eric Berg DC Bio: Dr. Berg, age 59, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan and is the Director of Dr. Berg Nutritionals. He no longer practices but focuses on health education through social media. Follow Me On Social Media: YouTube: https://www.yout https://www.youtube-nocookie.com/embed/Rra9FJ2lURI 257 2024-06-05T12:00:27.000Z 2026-10-22T19:04:42.922Z https://longevityharbor.com/en/watch/RuddhstoKpg NMN Supplements vs. NAD+ IV Therapy: Which Is Right for You? https://i.ytimg.com/vi/RuddhstoKpg/hqdefault.jpg 🌟In this informative video, we delve into the differences between NMN (Nicotinamide Mononucleotide) supplements and NAD+ (Nicotinamide Adenine Dinucleotide) IV therapy. Both NMN and NAD+ are gaining popularity for their potential anti-aging and health benefits, but which one is best suited for your needs?🌟 ✨Please visit our website: http://waveplasticsurgery.com ✨More about our doctors: https://waveplasticsurgery.com/about-wave/meet-the-doctors/ ✨Visit one of our 5 California locations! - Los Angeles - Costa Mesa - Rowland Heights - Arcadia - San Francisco ✨FOLLOW US ON SOCIAL MEDIA: Facebook: http://bit.ly/2PR35mD Instagram: http://bit.ly/39H2yfj WeChat: http://bit.ly/2TsHiEf ✨ABOUT US: Wave Plastic Surgery & Aesthetic Laser Center provides a luxurious environment for patients desiring outstanding outpatient surgery services in the Los Angeles, Orange County, Inland Empire, and San Francisco areas. We strive to provide cutting-edge and state-of-the-art technology and services for our patients in the field of aesthetic and plastic surgery, which also includes reconstructive surgery, injectables, and laser treatments. https://www.youtube-nocookie.com/embed/RuddhstoKpg 158 2024-03-05T20:00:16.000Z 2026-10-22T18:43:09.963Z https://longevityharbor.com/de/watch/RuddhstoKpg NMN Supplements vs. NAD+ IV Therapy: Which Is Right for You? https://i.ytimg.com/vi/RuddhstoKpg/hqdefault.jpg 🌟In this informative video, we delve into the differences between NMN (Nicotinamide Mononucleotide) supplements and NAD+ (Nicotinamide Adenine Dinucleotide) IV therapy. Both NMN and NAD+ are gaining popularity for their potential anti-aging and health benefits, but which one is best suited for your needs?🌟 ✨Please visit our website: http://waveplasticsurgery.com ✨More about our doctors: https://waveplasticsurgery.com/about-wave/meet-the-doctors/ ✨Visit one of our 5 California locations! - Los Angeles - Costa Mesa - Rowland Heights - Arcadia - San Francisco ✨FOLLOW US ON SOCIAL MEDIA: Facebook: http://bit.ly/2PR35mD Instagram: http://bit.ly/39H2yfj WeChat: http://bit.ly/2TsHiEf ✨ABOUT US: Wave Plastic Surgery & Aesthetic Laser Center provides a luxurious environment for patients desiring outstanding outpatient surgery services in the Los Angeles, Orange County, Inland Empire, and San Francisco areas. We strive to provide cutting-edge and state-of-the-art technology and services for our patients in the field of aesthetic and plastic surgery, which also includes reconstructive surgery, injectables, and laser treatments. https://www.youtube-nocookie.com/embed/RuddhstoKpg 158 2024-03-05T20:00:16.000Z 2026-10-22T18:43:09.963Z https://longevityharbor.com/en/watch/RxNCZ5MaPV4 Epigenetische Uhren: Biologisches vs. Chronologisches Alter mit Martin Berlet, CEO von EpiAge | #145 https://i.ytimg.com/vi/RxNCZ5MaPV4/hqdefault.jpg Blog-Artikel und alle Shownotes: https://thinkflowgrow.com/categories/epiage War das hilfreich? Kommentiere, teile und abonniere meinen Kanal. Danke! ▬▬▬ Newsletter▬▬▬▬ ➤ https://thinkflowgrow.mykajabi.com/newsletter ▬▬▬▬ 1:1 Holistic Health Coaching ▬▬▬▬ ➤ https://thinkflowgrow.com/coaching ▬▬▬▬ Kurse und Guides ▬▬▬▬ ➤ Alle Kurse https://thinkflowgrow.mykajabi.com ➤ Holistic Mobility Online Kurs https://thinkflowgrow.com/holisticmobilitykurs ▬▬▬ Podcast & Social Media ▬▬▬▬ Think Flow Grow Cast ➤ https://thinkflowgrow.mykajabi.com/podcasts/think-flow-grow-cast-mit-tim-boettner Instagram ➤ https://www.instagram.com/thinkflowgrow https://www.youtube-nocookie.com/embed/RxNCZ5MaPV4 2516 2023-05-31T22:00:22.000Z 2026-10-22T17:11:30.657Z https://longevityharbor.com/de/watch/RxNCZ5MaPV4 Epigenetische Uhren: Biologisches vs. Chronologisches Alter mit Martin Berlet, CEO von EpiAge | #145 https://i.ytimg.com/vi/RxNCZ5MaPV4/hqdefault.jpg Blog-Artikel und alle Shownotes: https://thinkflowgrow.com/categories/epiage War das hilfreich? Kommentiere, teile und abonniere meinen Kanal. Danke! ▬▬▬ Newsletter▬▬▬▬ ➤ https://thinkflowgrow.mykajabi.com/newsletter ▬▬▬▬ 1:1 Holistic Health Coaching ▬▬▬▬ ➤ https://thinkflowgrow.com/coaching ▬▬▬▬ Kurse und Guides ▬▬▬▬ ➤ Alle Kurse https://thinkflowgrow.mykajabi.com ➤ Holistic Mobility Online Kurs https://thinkflowgrow.com/holisticmobilitykurs ▬▬▬ Podcast & Social Media ▬▬▬▬ Think Flow Grow Cast ➤ https://thinkflowgrow.mykajabi.com/podcasts/think-flow-grow-cast-mit-tim-boettner Instagram ➤ https://www.instagram.com/thinkflowgrow https://www.youtube-nocookie.com/embed/RxNCZ5MaPV4 2516 2023-05-31T22:00:22.000Z 2026-10-22T17:11:30.657Z https://longevityharbor.com/en/watch/S-JA0f-wR8Y FASTING & NUTRITION PROTOCOLS FOR LONGEVITY & DISEASE PREVENTION | 055 DR. VALTER LONGO,PhD https://i.ytimg.com/vi/S-JA0f-wR8Y/hqdefault.jpg In this episode of the Ayık Kafa podcast, Prof. Valter Longo, a renowned researcher specializing in aging and longevity, discusses his groundbreaking work on the Fasting Mimicking Diet (FMD). Through decades of research, he developed the FMD as a clinically tested, five-day protocol designed to simulate the biological benefits of water-only fasting, such as improved metabolism, cellular repair, and the activation of stem cells, while minimizing the risks and discomforts typically associated with a strict fast. Longo contrasts water-only fasting with the FMD, emphasizing that water-only approaches can be difficult to follow and potentially unsafe without professional supervision, especially for individuals on certain medications or with specific health conditions. With carefully selected, plant-focused ingredients and precisely calibrated nutrient levels, the FMD helps users transition into a “fat-burning” mode while still supplying key nutrients. He also highlights the importance of a balanced, pescetarian-based “Longevity Diet,” combined with moderate exercise and limited eating windows (about 12 hours daily) to support long-term health. Whether someone’s goal is to prevent diabetes, reduce cancer risks, or simply maintain vitality, Dr.Longo believes that nourishing the body with the right foods and mindful fasting holds significant promise for extending both lifespan and healthspan. Turkish Voice Over 👉 https://youtu.be/bRfHNUPyOWc #EsraÇavuşoğlu #AyıkKafa #ElevatingLifeEvolvingHealth #Longevilab #profvalterlongo #longevitydiet #fastingmimickingdiet Prof. Valter Longo: Website: https://valterlongo.com/biography/ Instagram: https://www.instagram.com/prof_valterlongo/ 00:00-2:50 Dr. Longo’s early interest in aging. He explains how he began researching longevity during his second year in college and later joined Roy Walford’s lab at UCLA to study calorie restriction and genetics. 2:50-4:54 Dr.Longo's method of addressing diseases like cancer and diabetes through diet. 4:54-6:57 Differences between water https://www.youtube-nocookie.com/embed/S-JA0f-wR8Y 2962 2025-03-06T15:00:06.000Z 2026-10-22T19:32:32.145Z https://longevityharbor.com/de/watch/S-JA0f-wR8Y FASTING & NUTRITION PROTOCOLS FOR LONGEVITY & DISEASE PREVENTION | 055 DR. VALTER LONGO,PhD https://i.ytimg.com/vi/S-JA0f-wR8Y/hqdefault.jpg In this episode of the Ayık Kafa podcast, Prof. Valter Longo, a renowned researcher specializing in aging and longevity, discusses his groundbreaking work on the Fasting Mimicking Diet (FMD). Through decades of research, he developed the FMD as a clinically tested, five-day protocol designed to simulate the biological benefits of water-only fasting, such as improved metabolism, cellular repair, and the activation of stem cells, while minimizing the risks and discomforts typically associated with a strict fast. Longo contrasts water-only fasting with the FMD, emphasizing that water-only approaches can be difficult to follow and potentially unsafe without professional supervision, especially for individuals on certain medications or with specific health conditions. With carefully selected, plant-focused ingredients and precisely calibrated nutrient levels, the FMD helps users transition into a “fat-burning” mode while still supplying key nutrients. He also highlights the importance of a balanced, pescetarian-based “Longevity Diet,” combined with moderate exercise and limited eating windows (about 12 hours daily) to support long-term health. Whether someone’s goal is to prevent diabetes, reduce cancer risks, or simply maintain vitality, Dr.Longo believes that nourishing the body with the right foods and mindful fasting holds significant promise for extending both lifespan and healthspan. Turkish Voice Over 👉 https://youtu.be/bRfHNUPyOWc #EsraÇavuşoğlu #AyıkKafa #ElevatingLifeEvolvingHealth #Longevilab #profvalterlongo #longevitydiet #fastingmimickingdiet Prof. Valter Longo: Website: https://valterlongo.com/biography/ Instagram: https://www.instagram.com/prof_valterlongo/ 00:00-2:50 Dr. Longo’s early interest in aging. He explains how he began researching longevity during his second year in college and later joined Roy Walford’s lab at UCLA to study calorie restriction and genetics. 2:50-4:54 Dr.Longo's method of addressing diseases like cancer and diabetes through diet. 4:54-6:57 Differences between water https://www.youtube-nocookie.com/embed/S-JA0f-wR8Y 2962 2025-03-06T15:00:06.000Z 2026-10-22T19:32:32.145Z https://longevityharbor.com/en/watch/S3OQMhz2W_M MS Research: Using Epigenetic Clocks and Biomarkers to Assess Biological Aging https://i.ytimg.com/vi/S3OQMhz2W_M/hqdefault.jpg Guest: Yinan Zhang, MD Chronological age is the biggest early driver of disease progression in patients with multiple sclerosis (MS). That’s why a team of researchers wanted to explore whether biomarkers like p16 and the epigenetic clock can be used to assess biological aging in patients with MS. They found that while patients with MS are aging faster than people without MS based on the epigenetic clock biomarker, no chronological age correlation in p16 expression has been identified in patients with MS. Dive further into these findings with Dr. Yinan Zhang, an Assistant Professor of Neurology at Ohio State University who presented this research at the 2024 ACTRIMS Forum. https://www.youtube-nocookie.com/embed/S3OQMhz2W_M 330 2024-04-14T03:08:32.000Z 2026-10-22T17:43:35.264Z https://longevityharbor.com/de/watch/S3OQMhz2W_M MS Research: Using Epigenetic Clocks and Biomarkers to Assess Biological Aging https://i.ytimg.com/vi/S3OQMhz2W_M/hqdefault.jpg Guest: Yinan Zhang, MD Chronological age is the biggest early driver of disease progression in patients with multiple sclerosis (MS). That’s why a team of researchers wanted to explore whether biomarkers like p16 and the epigenetic clock can be used to assess biological aging in patients with MS. They found that while patients with MS are aging faster than people without MS based on the epigenetic clock biomarker, no chronological age correlation in p16 expression has been identified in patients with MS. Dive further into these findings with Dr. Yinan Zhang, an Assistant Professor of Neurology at Ohio State University who presented this research at the 2024 ACTRIMS Forum. https://www.youtube-nocookie.com/embed/S3OQMhz2W_M 330 2024-04-14T03:08:32.000Z 2026-10-22T17:43:35.264Z https://longevityharbor.com/en/watch/S8qJtUB6jRw Video description: epigenetic clocks and biological age explained https://i.ytimg.com/vi/S8qJtUB6jRw/hqdefault.jpg The description says the video contrasts chronological and biological age, presents DNA methylation clocks such as the Horvath Clock, PhenoAge and GrimAge, and notes that biological age appears responsive to lifestyle factors. https://www.youtube-nocookie.com/embed/S8qJtUB6jRw 579 2026-05-22T23:00:29.000Z 2026-10-23T00:37:15.014Z https://longevityharbor.com/de/watch/S8qJtUB6jRw Videobeschreibung: epigenetische Uhren und biologisches Alter erklärt https://i.ytimg.com/vi/S8qJtUB6jRw/hqdefault.jpg Laut Beschreibung vergleicht das Video chronologisches und biologisches Alter, stellt DNA-Methylierungs-Uhren wie die Horvath-Uhr, PhenoAge und GrimAge vor und merkt an, dass das biologische Alter auf Lebensstilfaktoren zu reagieren scheint. https://www.youtube-nocookie.com/embed/S8qJtUB6jRw 579 2026-05-22T23:00:29.000Z 2026-10-23T00:37:15.014Z https://longevityharbor.com/en/watch/SCUXlozS3Ww TAME: testing whether metformin can delay a cluster of age-related diseases https://i.ytimg.com/vi/SCUXlozS3Ww/hqdefault.jpg The description presents TAME as a planned multi-center trial of about 3,000 people that would test whether metformin delays a cluster of age-related conditions and whether aging itself can be treated as a medical condition. As of early 2026 it had not fully happened, and funding was the main hurdle. https://www.youtube-nocookie.com/embed/SCUXlozS3Ww 173 2026-03-01T16:58:04.000Z 2026-10-23T02:18:03.511Z https://longevityharbor.com/de/watch/SCUXlozS3Ww TAME: Prüft, ob Metformin einen Cluster altersbezogener Krankheiten verzögern kann https://i.ytimg.com/vi/SCUXlozS3Ww/hqdefault.jpg Die Beschreibung stellt TAME als geplante multizentrische Studie mit etwa 3.000 Personen vor, die prüfen soll, ob Metformin einen Cluster altersbezogener Erkrankungen verzögert und ob Altern selbst als medizinische Erkrankung behandelbar ist. Anfang 2026 war sie noch nicht vollständig durchgeführt; die Finanzierung war die Haupthürde. https://www.youtube-nocookie.com/embed/SCUXlozS3Ww 173 2026-03-01T16:58:04.000Z 2026-10-23T02:18:03.511Z https://longevityharbor.com/en/watch/SGaqJX4v9T8 Peter Attia: Top 5 Exercises to Boost Longevity & Reverse Aging https://i.ytimg.com/vi/SGaqJX4v9T8/hqdefault.jpg Please watch: "The BEST Fat Loss Supplement in 2025" https://www.youtube.com/watch?v=z8k-9P41A5U --~-- Peter Attia and Andrew Huberman discuss the best exercises for extending your lifespan and increasing strength and muscle mass. 00:00 Intro 00:26 All-Cause Mortality (ACM) 00:44 Muscle Mass & ACM 02:15 VO2 Max & ACM 02:58 Exercises to Improve ACM This video is a condensed and highly edited version of the full 170 minute podcast from @HubermanLab. We highly recommend watching the full episode and following the pod. Peter Attia is a Canadian-American author, physician, and researcher known for his work in longevity medicine. Andrew D. Huberman is an American neuroscientist and tenured associate professor in the department of neurobiology and psychiatry and behavioral sciences at Stanford University School of Medicine. Speaker: Andrew Huberman YouTube: @hubermanlab Source: https://www.youtube.com/watch?v=DTCmprPCDqc&t=1138s Follow Andrew Huberman online: Instagram: https://www.instagram.com/hubermanlab/ Twitter: https://twitter.com/hubermanlab/ Website: https://hubermanlab.com  Newsletter: https://hubermanlab.com/neural-network Fair Use Disclaimer Under section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use. * We do not own the rights to all content. They have, in accordance with fair use, been repurposed with the intent of educating and inspiring others. * We must state that in no way, shape or form are we intending to infringe rights of the copyright holder. Content used is strictly for research and education, all under the Fair Use law. * If any owners would like me to remove the video we have no problem with that, just send me a letter: therespirechannel@gmail.com.  #andrewhuberman #hubermanlab #longevity #antiaging #lifespan #hea https://www.youtube-nocookie.com/embed/SGaqJX4v9T8 391 2024-05-11T19:00:07.000Z 2026-10-22T17:43:36.924Z https://longevityharbor.com/de/watch/SGaqJX4v9T8 Peter Attia: Top 5 Exercises to Boost Longevity & Reverse Aging https://i.ytimg.com/vi/SGaqJX4v9T8/hqdefault.jpg Please watch: "The BEST Fat Loss Supplement in 2025" https://www.youtube.com/watch?v=z8k-9P41A5U --~-- Peter Attia and Andrew Huberman discuss the best exercises for extending your lifespan and increasing strength and muscle mass. 00:00 Intro 00:26 All-Cause Mortality (ACM) 00:44 Muscle Mass & ACM 02:15 VO2 Max & ACM 02:58 Exercises to Improve ACM This video is a condensed and highly edited version of the full 170 minute podcast from @HubermanLab. We highly recommend watching the full episode and following the pod. Peter Attia is a Canadian-American author, physician, and researcher known for his work in longevity medicine. Andrew D. Huberman is an American neuroscientist and tenured associate professor in the department of neurobiology and psychiatry and behavioral sciences at Stanford University School of Medicine. Speaker: Andrew Huberman YouTube: @hubermanlab Source: https://www.youtube.com/watch?v=DTCmprPCDqc&t=1138s Follow Andrew Huberman online: Instagram: https://www.instagram.com/hubermanlab/ Twitter: https://twitter.com/hubermanlab/ Website: https://hubermanlab.com  Newsletter: https://hubermanlab.com/neural-network Fair Use Disclaimer Under section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use. * We do not own the rights to all content. They have, in accordance with fair use, been repurposed with the intent of educating and inspiring others. * We must state that in no way, shape or form are we intending to infringe rights of the copyright holder. Content used is strictly for research and education, all under the Fair Use law. * If any owners would like me to remove the video we have no problem with that, just send me a letter: therespirechannel@gmail.com.  #andrewhuberman #hubermanlab #longevity #antiaging #lifespan #hea https://www.youtube-nocookie.com/embed/SGaqJX4v9T8 391 2024-05-11T19:00:07.000Z 2026-10-22T17:43:36.924Z https://longevityharbor.com/en/watch/SHP9YqDtIhw Faktencheck FASTEN: Gesundheit optimieren oder falscher Mythos? Prof. Kleine-Gunk https://i.ytimg.com/vi/SHP9YqDtIhw/hqdefault.jpg 🥑 🥦In nur 5 Tagen zu einem gesundheitlichen Neustart mit ProLon®: https://prolon-fasten.com/amm_prolon 🥑 🥦 Mit dem Code AMM_PROLON erhalten Sie 20% Rabatt auf alle Bestellungen. ----------- So sehr Fasten auch gesund ist – für viele Menschen ist es schwierig, es auch umzusetzen. Von daher ist es wichtig, Fastenformen zu entwickeln, die einfach durchzuführen und alltagstauglich sind. Diesbezüglich ist das von Professor Valter Longo entwickelte Scheinfasten (ProLon) derzeit sicherlich die beste Lösung. Eine weitere Möglichkeit besteht darin, bestimmte Effekte des Fastens durch eine gezielte Supplementierung zu erreichen. Hierzu gehört unter anderem die Sirtuinaktivierung, die auch durch sekundäre Pflanzenstoffe wie Resveratrol, Kurkumin, Quercetin, etc. gelingt. Auch der wichtige Faktor der Autophagie (die Beseitigung von molekularem Müll aus den Zellen) lässt sich nicht nur durch Fasten, sondern auch durch Supplemente stimulieren. Hier spielt das Spermidin eine Schlüsselrolle. 👉 Mehr Informationen zum Thema Anti-Aging Medizin finden Sie unter: https://www.gsaam.de/ 👉 Die kleine Fastenfibel der NährstoffAllianz für Sie zum Download: https://naehrstoffallianz.dsgip.de/medien-downloads/die-kleine-fastenfibel/ 📚 Unsere Buchempfehlungen zum Thema Fasten: 📙 https://spitzen-praevention.com/buchempfehlung/hobelsberger-kleine-gunk-das-neue-easy-fasten/ 📘 https://spitzen-praevention.com/buchempfehlung/becker-mangiameli-five-days-only/ 📗 https://spitzen-praevention.com/buchempfehlung/iss-dich-jung-die-longevita-diaet/ 📕 https://spitzen-praevention.com/buchempfehlung/buchinger-heilfasten-mein-7-tage-programm-fuer-zu-hause/ ----------- ⛱☂ Spannen Sie Ihren Schutzschirm für ein gesundes Leben auf ❗❓ 25 Fragen zu Prävention und Gesundheit ❓❗ Nutzen Sie jetzt unser neues Online-Tool, um Ihre derzeitige gesundheitliche Positionierung anhand von 25 Fragen qualitativ einzuschätzen. Kostenfreier Zugang unter: 👉 https://amm2go.de/yt1-gesund-leben ----------- 🙏 Bleiben Sie gesund! 🙏 Ihr AMM-Team #Gesundheit #ernähr https://www.youtube-nocookie.com/embed/SHP9YqDtIhw 1826 2023-03-17T09:17:47.000Z 2026-10-22T17:43:37.681Z https://longevityharbor.com/de/watch/SHP9YqDtIhw Faktencheck FASTEN: Gesundheit optimieren oder falscher Mythos? Prof. Kleine-Gunk https://i.ytimg.com/vi/SHP9YqDtIhw/hqdefault.jpg 🥑 🥦In nur 5 Tagen zu einem gesundheitlichen Neustart mit ProLon®: https://prolon-fasten.com/amm_prolon 🥑 🥦 Mit dem Code AMM_PROLON erhalten Sie 20% Rabatt auf alle Bestellungen. ----------- So sehr Fasten auch gesund ist – für viele Menschen ist es schwierig, es auch umzusetzen. Von daher ist es wichtig, Fastenformen zu entwickeln, die einfach durchzuführen und alltagstauglich sind. Diesbezüglich ist das von Professor Valter Longo entwickelte Scheinfasten (ProLon) derzeit sicherlich die beste Lösung. Eine weitere Möglichkeit besteht darin, bestimmte Effekte des Fastens durch eine gezielte Supplementierung zu erreichen. Hierzu gehört unter anderem die Sirtuinaktivierung, die auch durch sekundäre Pflanzenstoffe wie Resveratrol, Kurkumin, Quercetin, etc. gelingt. Auch der wichtige Faktor der Autophagie (die Beseitigung von molekularem Müll aus den Zellen) lässt sich nicht nur durch Fasten, sondern auch durch Supplemente stimulieren. Hier spielt das Spermidin eine Schlüsselrolle. 👉 Mehr Informationen zum Thema Anti-Aging Medizin finden Sie unter: https://www.gsaam.de/ 👉 Die kleine Fastenfibel der NährstoffAllianz für Sie zum Download: https://naehrstoffallianz.dsgip.de/medien-downloads/die-kleine-fastenfibel/ 📚 Unsere Buchempfehlungen zum Thema Fasten: 📙 https://spitzen-praevention.com/buchempfehlung/hobelsberger-kleine-gunk-das-neue-easy-fasten/ 📘 https://spitzen-praevention.com/buchempfehlung/becker-mangiameli-five-days-only/ 📗 https://spitzen-praevention.com/buchempfehlung/iss-dich-jung-die-longevita-diaet/ 📕 https://spitzen-praevention.com/buchempfehlung/buchinger-heilfasten-mein-7-tage-programm-fuer-zu-hause/ ----------- ⛱☂ Spannen Sie Ihren Schutzschirm für ein gesundes Leben auf ❗❓ 25 Fragen zu Prävention und Gesundheit ❓❗ Nutzen Sie jetzt unser neues Online-Tool, um Ihre derzeitige gesundheitliche Positionierung anhand von 25 Fragen qualitativ einzuschätzen. Kostenfreier Zugang unter: 👉 https://amm2go.de/yt1-gesund-leben ----------- 🙏 Bleiben Sie gesund! 🙏 Ihr AMM-Team #Gesundheit #ernähr https://www.youtube-nocookie.com/embed/SHP9YqDtIhw 1826 2023-03-17T09:17:47.000Z 2026-10-22T17:43:37.681Z https://longevityharbor.com/en/watch/SKWL2QEiGJU Video description: resistance training, muscle loss and healthy aging claims https://i.ytimg.com/vi/SKWL2QEiGJU/hqdefault.jpg The description presents resistance training as a key habit for healthy aging and says the video covers muscle loss from the 30s, grip strength and longevity, muscle as an endocrine organ, bone density, brain health and a training plan. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/SKWL2QEiGJU 1165 2026-09-12T14:00:09.000Z 2026-10-22T22:16:54.143Z https://longevityharbor.com/de/watch/SKWL2QEiGJU Videobeschreibung: Krafttraining, Muskelverlust und Aussagen zum gesunden Altern https://i.ytimg.com/vi/SKWL2QEiGJU/hqdefault.jpg Die Beschreibung stellt Krafttraining als wichtige Gewohnheit für gesundes Altern dar und nennt als Videothemen Muskelverlust ab den 30ern, Griffkraft und Langlebigkeit, Muskel als endokrines Organ, Knochendichte, Gehirngesundheit und einen Trainingsplan. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/SKWL2QEiGJU 1165 2026-09-12T14:00:09.000Z 2026-10-22T22:16:54.143Z https://longevityharbor.com/en/watch/SP2MNMFJlUg Video description: aging biomarkers, senolytics and health span with Matt Yousefzadeh https://i.ytimg.com/vi/SP2MNMFJlUg/hqdefault.jpg The description says Matt Yousefzadeh of Columbia University Medical Center discusses aging biomarkers, biological versus chronological age, senolytics, cellular senescence, epigenetic clocks, exercise and caloric restriction, and why health span matters more than lifespan. https://www.youtube-nocookie.com/embed/SP2MNMFJlUg 2861 2026-06-28T23:00:10.000Z 2026-10-22T23:46:16.625Z https://longevityharbor.com/de/watch/SP2MNMFJlUg Videobeschreibung: Alternsbiomarker, Senolytika und Health Span mit Matt Yousefzadeh https://i.ytimg.com/vi/SP2MNMFJlUg/hqdefault.jpg Laut Beschreibung spricht Matt Yousefzadeh vom Columbia University Medical Center über Alternsbiomarker, biologisches versus chronologisches Alter, Senolytika, zelluläre Seneszenz, epigenetische Uhren, Bewegung und Kalorienrestriktion und darüber, warum Health Span wichtiger als Lebensspanne ist. https://www.youtube-nocookie.com/embed/SP2MNMFJlUg 2861 2026-06-28T23:00:10.000Z 2026-10-22T23:46:16.625Z https://longevityharbor.com/en/watch/SQ54wma-JQA Advice From the #1 Longevity Doctor: Add 10 Years to Your Life With 3 Simple Habits https://i.ytimg.com/vi/SQ54wma-JQA/hqdefault.jpg Order your copy of The Let Them Theory 👉 https://melrob.co/let-them-theory 👈 The #1 Best Selling Book of 2025 🔥 Discover how much power you truly have. It all begins with two simple words. Let Them. — Today’s episode could change (or save) your life. It’s a must-listen. You’ll hear from the world’s leading longevity doctor about the simple, proven changes that will help you live longer, feel better, and prevent diseases like cancer, heart disease, and dementia. Today, Mel sits down with one of the world’s most respected scientists, Dr. Eric Topol — a pioneering cardiologist, longevity researcher, and one of the top 10 most cited medical researchers alive today — to reveal the real, evidence-based approach to longevity. This is the science and art of living better, longer. Forget the trendy anti-aging supplements, infusions, and miracle cures: Dr. Topol is here to give you the truth on exactly what the science says about how to reverse the biological age of your organs, add up to a decade of healthy years to your life, and avoid the biggest killers we all fear. You’ll learn: -The #1 free intervention proven to slow aging -The three everyday habits that are aging you faster (and how to fix them) -How to exercise and eat for optimal health and longevity -The truth about supplements, IV drips, and anti-aging clinics -Why loneliness is as dangerous to your health as smoking -How exercise can be more effective than antidepressants -The breakthrough blood tests and tools that could predict — and prevent — diseases decades before they happen This conversation is full of science and hope, because as Dr. Topol says: “It has never been a more exciting time in medicine.” Whether you want to prevent disease, feel better, or just live a longer, healthier life, this episode will give you the real plan for how to do it. If you love someone, send them this episode. It could save their life. For more resources related to today’s episode, click here for the podcast episode page: https://www.melrobbins.c https://www.youtube-nocookie.com/embed/SQ54wma-JQA 3927 2025-05-01T09:00:42.000Z 2026-10-22T18:43:11.729Z https://longevityharbor.com/de/watch/SQ54wma-JQA Advice From the #1 Longevity Doctor: Add 10 Years to Your Life With 3 Simple Habits https://i.ytimg.com/vi/SQ54wma-JQA/hqdefault.jpg Order your copy of The Let Them Theory 👉 https://melrob.co/let-them-theory 👈 The #1 Best Selling Book of 2025 🔥 Discover how much power you truly have. It all begins with two simple words. Let Them. — Today’s episode could change (or save) your life. It’s a must-listen. You’ll hear from the world’s leading longevity doctor about the simple, proven changes that will help you live longer, feel better, and prevent diseases like cancer, heart disease, and dementia. Today, Mel sits down with one of the world’s most respected scientists, Dr. Eric Topol — a pioneering cardiologist, longevity researcher, and one of the top 10 most cited medical researchers alive today — to reveal the real, evidence-based approach to longevity. This is the science and art of living better, longer. Forget the trendy anti-aging supplements, infusions, and miracle cures: Dr. Topol is here to give you the truth on exactly what the science says about how to reverse the biological age of your organs, add up to a decade of healthy years to your life, and avoid the biggest killers we all fear. You’ll learn: -The #1 free intervention proven to slow aging -The three everyday habits that are aging you faster (and how to fix them) -How to exercise and eat for optimal health and longevity -The truth about supplements, IV drips, and anti-aging clinics -Why loneliness is as dangerous to your health as smoking -How exercise can be more effective than antidepressants -The breakthrough blood tests and tools that could predict — and prevent — diseases decades before they happen This conversation is full of science and hope, because as Dr. Topol says: “It has never been a more exciting time in medicine.” Whether you want to prevent disease, feel better, or just live a longer, healthier life, this episode will give you the real plan for how to do it. If you love someone, send them this episode. It could save their life. For more resources related to today’s episode, click here for the podcast episode page: https://www.melrobbins.c https://www.youtube-nocookie.com/embed/SQ54wma-JQA 3927 2025-05-01T09:00:42.000Z 2026-10-22T18:43:11.729Z https://longevityharbor.com/en/watch/SQu-_wbtPlc Video description: mTOR pathway linking nutrients, energy and growth factors to cell growth https://i.ytimg.com/vi/SQu-_wbtPlc/hqdefault.jpg According to the description, the episode explores mTOR as a signaling pathway that integrates nutrient, energy and growth-factor signals and regulates protein synthesis, cell growth and metabolic balance; the creator links it to aging and longevity research. https://www.youtube-nocookie.com/embed/SQu-_wbtPlc 384 2026-03-07T00:40:00.000Z 2026-10-23T02:12:20.094Z https://longevityharbor.com/de/watch/SQu-_wbtPlc Videobeschreibung: mTOR-Weg verbindet Nährstoffe, Energie und Wachstumsfaktoren mit Zellwachstum https://i.ytimg.com/vi/SQu-_wbtPlc/hqdefault.jpg Laut Beschreibung behandelt die Episode mTOR als Signalweg, der Nährstoff-, Energie- und Wachstumsfaktorsignale integriert und Proteinsynthese, Zellwachstum sowie Stoffwechselgleichgewicht reguliert; der Ersteller verknüpft dies mit Alterns- und Langlebigkeitsforschung. https://www.youtube-nocookie.com/embed/SQu-_wbtPlc 384 2026-03-07T00:40:00.000Z 2026-10-23T02:12:20.094Z https://longevityharbor.com/en/watch/SQuyXar_Rw0 NMN explained Cata-Kor USA #nmn #nad #supplementsthatwork #antiaging #ad https://i.ytimg.com/vi/SQuyXar_Rw0/hqdefault.jpg NMN explained Cata-Kor USA #nmn #nad #supplementsthatwork #antiaging #ad https://www.youtube-nocookie.com/embed/SQuyXar_Rw0 108 2026-09-01T21:47:29.000Z 2026-10-22T19:32:37.666Z https://longevityharbor.com/de/watch/SQuyXar_Rw0 NMN explained Cata-Kor USA #nmn #nad #supplementsthatwork #antiaging #ad https://i.ytimg.com/vi/SQuyXar_Rw0/hqdefault.jpg NMN explained Cata-Kor USA #nmn #nad #supplementsthatwork #antiaging #ad https://www.youtube-nocookie.com/embed/SQuyXar_Rw0 108 2026-09-01T21:47:29.000Z 2026-10-22T19:32:37.666Z https://longevityharbor.com/en/watch/SQwEFiskBgo Heidi Pak - Fasting, Not Calories, Drives the Response to a Calorie Restricted Diet https://i.ytimg.com/vi/SQwEFiskBgo/hqdefault.jpg Heidi Pak, University of Wisconsin, USA, presents at the 2020 Aging Research and Drug Discovery conference. About the Aging Research and Drug Discovery meeting: According to the United Nations, the proportion of people aged over 65 now outnumber children younger than 5. The enormous growth in the elderly population is posing a socioeconomic challenge to societies worldwide, and necessitates new sweeping interventions for age-associated diseases. This year we have an incredibly exciting program with global thought-leaders sharing their latest insights into aging and how we target aging process ensuring everyone lives a healthier and longer life. Welcome to the 7th Aging Research and Drug Discovery Meeting. Read more on: www.agingpharma.org https://www.youtube-nocookie.com/embed/SQwEFiskBgo 557 2020-09-18T07:50:39.000Z 2026-10-22T17:43:38.466Z https://longevityharbor.com/de/watch/SQwEFiskBgo Heidi Pak - Fasting, Not Calories, Drives the Response to a Calorie Restricted Diet https://i.ytimg.com/vi/SQwEFiskBgo/hqdefault.jpg Heidi Pak, University of Wisconsin, USA, presents at the 2020 Aging Research and Drug Discovery conference. About the Aging Research and Drug Discovery meeting: According to the United Nations, the proportion of people aged over 65 now outnumber children younger than 5. The enormous growth in the elderly population is posing a socioeconomic challenge to societies worldwide, and necessitates new sweeping interventions for age-associated diseases. This year we have an incredibly exciting program with global thought-leaders sharing their latest insights into aging and how we target aging process ensuring everyone lives a healthier and longer life. Welcome to the 7th Aging Research and Drug Discovery Meeting. Read more on: www.agingpharma.org https://www.youtube-nocookie.com/embed/SQwEFiskBgo 557 2020-09-18T07:50:39.000Z 2026-10-22T17:43:38.466Z https://longevityharbor.com/en/watch/SRFrRCC8rCE Measuring Time In Molecules: The Science Of Biological Age https://i.ytimg.com/vi/SRFrRCC8rCE/hqdefault.jpg Measuring Time In Molecules With Dr. Laurena Law ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ In this video, I invite Dr Chandni Kumar, a friend and repeat guest to discuss DNA methylation clocks and proteomic clocks which are being developed to measure biological age as well as their development to be used as biomarkers to assess longevity interventions. You can subscribe to her here: @DDHS_Podcast References provided by Dr Kumar: [1] Gillespie, C.A., Chowdhury, A., Quinn, K.A. et al. Fundamentals of DNA methylation in development. Pediatr Res (2024). https://doi.org/10.1038/s41390-024-03674-7 [2] Moore, L., Le, T. & Fan, G. DNA Methylation and Its Basic unction. Neuropsychopharmacol 38, 23–38 (2013). https://doi.org/10.1038/npp.2012.112 [3] Lakshminarasimhan, Ranjani, and Gangning Liang. “The Role of DNA Methylation in Cancer.” Advances in experimental medicine and biology vol. 945 (2016): 151-172. doi:10.1007/978-3-319-43624-1_7 [4] Tsai Y-H, Mitra P, Taniar D and Pai T-W (2025) DNA methylation biomarker analysis from low-survival-rate cancers based on genetic functional approaches. Front. Bioinform. 5:1523524. doi: 10.3389/fbinf.2025.1523524 [5] Nadiger, N., Veed, J.K., Chinya Nataraj, P. et al. DNA methylation and type 2 diabetes: a systematic review. Clin Epigenet 16, 67 (2024). https://doi.org/10.1186/s13148-024-01670-6 [6] Kwon, HJ., Shin, S.H., Kim, H.H. et al. Advances in methylation analysis of liquid biopsy in early cancer detection of colorectal and lung cancer. Sci Rep 13, 13502 (2023). https://doi.org/10.1038/s41598-023-40611-w [7] Gibson, Jude et al. “A meta-analysis of genome-wide association studies of epigenetic age acceleration.” PLoS genetics vol. 15,11 e1008104. 18 Nov. 2019, doi:10.1371/journal.pgen.1008104 [8] Shireby, Gemma L et al. “Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex.” Brain : a journal of neurology vol. 143,12 (2020): 3763-3775. doi:10.1093/brain/awaa334 [9] Fraszczyk, Eliza et al. “DNA methylation trajectories and accelerated epi https://www.youtube-nocookie.com/embed/SRFrRCC8rCE 4352 2025-06-11T03:00:07.000Z 2026-10-22T19:21:27.793Z https://longevityharbor.com/de/watch/SRFrRCC8rCE Measuring Time In Molecules: The Science Of Biological Age https://i.ytimg.com/vi/SRFrRCC8rCE/hqdefault.jpg Measuring Time In Molecules With Dr. Laurena Law ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ In this video, I invite Dr Chandni Kumar, a friend and repeat guest to discuss DNA methylation clocks and proteomic clocks which are being developed to measure biological age as well as their development to be used as biomarkers to assess longevity interventions. You can subscribe to her here: @DDHS_Podcast References provided by Dr Kumar: [1] Gillespie, C.A., Chowdhury, A., Quinn, K.A. et al. Fundamentals of DNA methylation in development. Pediatr Res (2024). https://doi.org/10.1038/s41390-024-03674-7 [2] Moore, L., Le, T. & Fan, G. DNA Methylation and Its Basic unction. Neuropsychopharmacol 38, 23–38 (2013). https://doi.org/10.1038/npp.2012.112 [3] Lakshminarasimhan, Ranjani, and Gangning Liang. “The Role of DNA Methylation in Cancer.” Advances in experimental medicine and biology vol. 945 (2016): 151-172. doi:10.1007/978-3-319-43624-1_7 [4] Tsai Y-H, Mitra P, Taniar D and Pai T-W (2025) DNA methylation biomarker analysis from low-survival-rate cancers based on genetic functional approaches. Front. Bioinform. 5:1523524. doi: 10.3389/fbinf.2025.1523524 [5] Nadiger, N., Veed, J.K., Chinya Nataraj, P. et al. DNA methylation and type 2 diabetes: a systematic review. Clin Epigenet 16, 67 (2024). https://doi.org/10.1186/s13148-024-01670-6 [6] Kwon, HJ., Shin, S.H., Kim, H.H. et al. Advances in methylation analysis of liquid biopsy in early cancer detection of colorectal and lung cancer. Sci Rep 13, 13502 (2023). https://doi.org/10.1038/s41598-023-40611-w [7] Gibson, Jude et al. “A meta-analysis of genome-wide association studies of epigenetic age acceleration.” PLoS genetics vol. 15,11 e1008104. 18 Nov. 2019, doi:10.1371/journal.pgen.1008104 [8] Shireby, Gemma L et al. “Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex.” Brain : a journal of neurology vol. 143,12 (2020): 3763-3775. doi:10.1093/brain/awaa334 [9] Fraszczyk, Eliza et al. “DNA methylation trajectories and accelerated epi https://www.youtube-nocookie.com/embed/SRFrRCC8rCE 4352 2025-06-11T03:00:07.000Z 2026-10-22T19:21:27.793Z https://longevityharbor.com/en/watch/SS1NFMRXfhE Oncotarget | Exploratory Study of Metformin and Rapamycin as Maintenance Therapy https://i.ytimg.com/vi/SS1NFMRXfhE/hqdefault.jpg Volume 11, Number 21 of Oncotarget reported that eligible patients with stable or responding mPDA after 6 months on chemotherapy were randomized 1:1 to metformin alone or with rapamycin, stratified by prior treatment with FOLFIRINOX. Metformin +/ rapamycin maintenance for mPDA was well-tolerated and several patients achieved stable disease associated with exceptionally long survival. Dr. Dung T. Le from The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, 21287 said, "Pancreatic ductal adenocarcinoma (PDA) is aggressive cancer with high mortality at all stages and limited treatment options in the advanced setting." Metformin is an antidiabetic drug in the biguanide class of agents which inhibits mTOR complex 1 primarily through AMP-kinase activation. A synergistic effect of the combination of metformin with rapamycin was suggested by preclinical studies demonstrating enhanced inhibition of mTOR in a pancreatic cancer cell line and better growth inhibition of pancreatic cancer cells in a xenograft tumor model with the combination than either agent alone. Based on this, they conducted an exploratory study of metformin with or without rapamycin in patients with mPDA in the maintenance setting. The Le Research Team concluded in their Oncotarget Research Article, "the administration of metformin with or without rapamycin in patients with mPDA who achieve a response to chemotherapy is well-tolerated and was associated with better than expected overall survival in this study. Additional studies are needed to prospectively evaluate the role of these agents compared to a maintenance chemotherapy or observation only approach." Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.27586 DOI - https://doi.org/10.18632/oncotarget.27586 Full text - https://www.oncotarget.com/article/27586/text/ Correspondence to - Dung T. Le - dle@jhmi.edu Keywords - pancreatic cancer, mTOR inhibition, maintenance therapy, metfo https://www.youtube-nocookie.com/embed/SS1NFMRXfhE 381 2021-11-12T18:35:02.000Z 2026-10-22T17:43:41.801Z https://longevityharbor.com/de/watch/SS1NFMRXfhE Oncotarget | Exploratory Study of Metformin and Rapamycin as Maintenance Therapy https://i.ytimg.com/vi/SS1NFMRXfhE/hqdefault.jpg Volume 11, Number 21 of Oncotarget reported that eligible patients with stable or responding mPDA after 6 months on chemotherapy were randomized 1:1 to metformin alone or with rapamycin, stratified by prior treatment with FOLFIRINOX. Metformin +/ rapamycin maintenance for mPDA was well-tolerated and several patients achieved stable disease associated with exceptionally long survival. Dr. Dung T. Le from The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, 21287 said, "Pancreatic ductal adenocarcinoma (PDA) is aggressive cancer with high mortality at all stages and limited treatment options in the advanced setting." Metformin is an antidiabetic drug in the biguanide class of agents which inhibits mTOR complex 1 primarily through AMP-kinase activation. A synergistic effect of the combination of metformin with rapamycin was suggested by preclinical studies demonstrating enhanced inhibition of mTOR in a pancreatic cancer cell line and better growth inhibition of pancreatic cancer cells in a xenograft tumor model with the combination than either agent alone. Based on this, they conducted an exploratory study of metformin with or without rapamycin in patients with mPDA in the maintenance setting. The Le Research Team concluded in their Oncotarget Research Article, "the administration of metformin with or without rapamycin in patients with mPDA who achieve a response to chemotherapy is well-tolerated and was associated with better than expected overall survival in this study. Additional studies are needed to prospectively evaluate the role of these agents compared to a maintenance chemotherapy or observation only approach." Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.27586 DOI - https://doi.org/10.18632/oncotarget.27586 Full text - https://www.oncotarget.com/article/27586/text/ Correspondence to - Dung T. Le - dle@jhmi.edu Keywords - pancreatic cancer, mTOR inhibition, maintenance therapy, metfo https://www.youtube-nocookie.com/embed/SS1NFMRXfhE 381 2021-11-12T18:35:02.000Z 2026-10-22T17:43:41.801Z https://longevityharbor.com/en/watch/Sas9k3Eu2mQ Circadian Rhythm Disruption: Health Risks and Consequences https://i.ytimg.com/vi/Sas9k3Eu2mQ/hqdefault.jpg Episode 259: Dr. Charlotte Förster explains how disrupting your circadian rhythm can wreak havoc on your health. Body clocks, normally synced by the brain, fall out of phase, leading to hunger at night. Even worse, the immune system's nighttime work is disrupted. It may lead to cardiovascular issues, weight gain, and even cancer. Go to the Mind & Matter page for full episode: https://www.youtube.com/@MindAndMatter Not medical advice. Post questions in the comments. #CircadianRhythm #SleepScience #ImmuneHealth #HealthPodcast #Neuroscience https://www.youtube-nocookie.com/embed/Sas9k3Eu2mQ 109 2025-11-07T14:44:37.000Z 2026-10-22T18:54:00.958Z https://longevityharbor.com/de/watch/Sas9k3Eu2mQ Circadian Rhythm Disruption: Health Risks and Consequences https://i.ytimg.com/vi/Sas9k3Eu2mQ/hqdefault.jpg Episode 259: Dr. Charlotte Förster explains how disrupting your circadian rhythm can wreak havoc on your health. Body clocks, normally synced by the brain, fall out of phase, leading to hunger at night. Even worse, the immune system's nighttime work is disrupted. It may lead to cardiovascular issues, weight gain, and even cancer. Go to the Mind & Matter page for full episode: https://www.youtube.com/@MindAndMatter Not medical advice. Post questions in the comments. #CircadianRhythm #SleepScience #ImmuneHealth #HealthPodcast #Neuroscience https://www.youtube-nocookie.com/embed/Sas9k3Eu2mQ 109 2025-11-07T14:44:37.000Z 2026-10-22T18:54:00.958Z https://longevityharbor.com/en/watch/Sc6mpNbeDAM Video description: rapamycin and metformin in geroscience, with a translational gap https://i.ytimg.com/vi/Sc6mpNbeDAM/hqdefault.jpg The description says the episode examines rapamycin and metformin biology, including tissue-specific effects, tradeoffs and the gap between animal lifespan results and human proof. https://www.youtube-nocookie.com/embed/Sc6mpNbeDAM 3300 2026-05-19T20:22:08.000Z 2026-10-23T00:37:59.239Z https://longevityharbor.com/de/watch/Sc6mpNbeDAM Videobeschreibung: Rapamycin und Metformin in der Geroscience mit Übersetzungslücke https://i.ytimg.com/vi/Sc6mpNbeDAM/hqdefault.jpg Laut Beschreibung untersucht die Episode die Biologie von Rapamycin und Metformin, darunter gewebespezifische Effekte, Zielkonflikte und die Lücke zwischen Lebensverlängerung im Tiermodell und menschlichem Wirksamkeitsnachweis. https://www.youtube-nocookie.com/embed/Sc6mpNbeDAM 3300 2026-05-19T20:22:08.000Z 2026-10-23T00:37:59.239Z https://longevityharbor.com/en/watch/SdlRHU3XF0E Aging, mTOR, Sirtuins, Rapamycin, Metformin, the Truth of Resveratrol & Longevity Supplements, Da... https://i.ytimg.com/vi/SdlRHU3XF0E/hqdefault.jpg Send a text (https://www.buzzsprout.com/twilio/text_messages/1535644/open_sms) About the guest: Matt Kaeberlein, PhD is a Professor of at the University of Washington and CEO of OptiSpan. His research focuses on the biology of aging and longevity. Episode summary: Nick and Dr. Kaeberlein discuss: the biology of aging; mTOR, FGF1, growth & metabolism; sirtuins, NAD & NMN; longevity drugs like metformin & rapamycin; facts & myths about longevity molecules like resveratrol & taurine; controversies in aging research related to prominent Harvard researcher David Sinclair; epigenetic clocks; healthspan & lifespan; and more. *This content is never meant to serve as medical advice. Support the show (https://mindandmatter.substack.com/p/how-to-support-mind-and-matter) Health Products by M&M Partners: • SporesMD (https://sporesmd.com/?ref=mindmatter) : Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. • Lumen device (https://www.lumen.me/shop?fid=8731&discount=MINDMATTER) : Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. • AquaTru (https://aquatruwater.com/?oid2=50&affid2=11307) : Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. • Seed Oil Scout (https://download.seedoilscout.com/xhLZ?af_xp=custom&pid=affiliate&c=Nick%20Jikomes) : Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. • KetoCitra (https://santabarbaranutrients.com/products/ketocitra) —Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts (https://mindandmatter.substack.com/p/how-to-support-mind-and-matter) https://www.youtube-nocookie.com/embed/SdlRHU3XF0E 8912 2025-11-04T01:19:14.000Z 2026-10-22T17:43:41.807Z https://longevityharbor.com/de/watch/SdlRHU3XF0E Aging, mTOR, Sirtuins, Rapamycin, Metformin, the Truth of Resveratrol & Longevity Supplements, Da... https://i.ytimg.com/vi/SdlRHU3XF0E/hqdefault.jpg Send a text (https://www.buzzsprout.com/twilio/text_messages/1535644/open_sms) About the guest: Matt Kaeberlein, PhD is a Professor of at the University of Washington and CEO of OptiSpan. His research focuses on the biology of aging and longevity. Episode summary: Nick and Dr. Kaeberlein discuss: the biology of aging; mTOR, FGF1, growth & metabolism; sirtuins, NAD & NMN; longevity drugs like metformin & rapamycin; facts & myths about longevity molecules like resveratrol & taurine; controversies in aging research related to prominent Harvard researcher David Sinclair; epigenetic clocks; healthspan & lifespan; and more. *This content is never meant to serve as medical advice. Support the show (https://mindandmatter.substack.com/p/how-to-support-mind-and-matter) Health Products by M&M Partners: • SporesMD (https://sporesmd.com/?ref=mindmatter) : Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. • Lumen device (https://www.lumen.me/shop?fid=8731&discount=MINDMATTER) : Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. • AquaTru (https://aquatruwater.com/?oid2=50&affid2=11307) : Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. • Seed Oil Scout (https://download.seedoilscout.com/xhLZ?af_xp=custom&pid=affiliate&c=Nick%20Jikomes) : Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. • KetoCitra (https://santabarbaranutrients.com/products/ketocitra) —Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts (https://mindandmatter.substack.com/p/how-to-support-mind-and-matter) https://www.youtube-nocookie.com/embed/SdlRHU3XF0E 8912 2025-11-04T01:19:14.000Z 2026-10-22T17:43:41.807Z https://longevityharbor.com/en/watch/SeNB1MtH8zo Zombie cells: how senescence is described and how senolytics are researched https://i.ytimg.com/vi/SeNB1MtH8zo/hqdefault.jpg The description presents a science documentary on cellular senescence: damaged cells stop dividing, enter a toxic state via p16 and p53 signals, and release a harmful SASP cocktail; senolytic research with quercetin, fisetin and dasatinib is said to target these cells. https://www.youtube-nocookie.com/embed/SeNB1MtH8zo 391 2026-10-04T15:00:14.000Z 2026-10-22T21:25:54.091Z https://longevityharbor.com/de/watch/SeNB1MtH8zo Zombie-Zellen: Wie Seneszenz beschrieben und wie Senolytika erforscht werden https://i.ytimg.com/vi/SeNB1MtH8zo/hqdefault.jpg Die Beschreibung stellt eine Wissenschaftsdokumentation über zelluläre Seneszenz vor: geschädigte Zellen teilen sich nicht mehr, gehen über p16- und p53-Signalwege in einen toxischen Zustand über und setzen einen schädlichen SASP-Cocktail frei; Senolytika-Forschung mit Quercetin, Fisetin und Dasatinib soll diese Zellen gezielt angreifen. https://www.youtube-nocookie.com/embed/SeNB1MtH8zo 391 2026-10-04T15:00:14.000Z 2026-10-22T21:25:54.091Z https://longevityharbor.com/en/watch/Si6CGiU62V0 Is fasting beneficial for longevity? https://i.ytimg.com/vi/Si6CGiU62V0/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/Io5xV9rtbm4?si=YbHDA2iR02950c9u Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 300 ‒ Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, & more. In this clip, they discuss: - What would be a good fasting protocol? - Why Peter stopped his fasting protocol - The downsides of fasting - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the as https://www.youtube-nocookie.com/embed/Si6CGiU62V0 723 2024-05-08T16:00:19.000Z 2026-10-22T17:43:38.457Z https://longevityharbor.com/de/watch/Si6CGiU62V0 Is fasting beneficial for longevity? https://i.ytimg.com/vi/Si6CGiU62V0/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/Io5xV9rtbm4?si=YbHDA2iR02950c9u Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 300 ‒ Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, & more. In this clip, they discuss: - What would be a good fasting protocol? - Why Peter stopped his fasting protocol - The downsides of fasting - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the as https://www.youtube-nocookie.com/embed/Si6CGiU62V0 723 2024-05-08T16:00:19.000Z 2026-10-22T17:43:38.457Z https://longevityharbor.com/en/watch/Sn6mUtc_vjY Why Aging Might Best Be Thought of as a Disease https://i.ytimg.com/vi/Sn6mUtc_vjY/hqdefault.jpg As medical advances have helped extend lifespans, older people still experience a decline in quality of life in their later years as a result of diseases associated with aging. This can cause a loss of independence, isolation, and suffering. The Biogerontology Research Foundation, a United Kingdom-based nonprofit, is funding work to understand the molecular and cellular processes of aging and develop biotechnological interventions to halt or reverse damage from it. We spoke to Franco Cortese, deputy director of The Biogerontology Research Foundation, about a new report it’s issued that characterizes the longevity and geroscience landscape today, areas of research that hold promise, and why aging might best be thought of as a disease. https://www.youtube-nocookie.com/embed/Sn6mUtc_vjY 1117 2024-08-30T02:04:42.000Z 2026-10-22T19:04:38.889Z https://longevityharbor.com/de/watch/Sn6mUtc_vjY Why Aging Might Best Be Thought of as a Disease https://i.ytimg.com/vi/Sn6mUtc_vjY/hqdefault.jpg As medical advances have helped extend lifespans, older people still experience a decline in quality of life in their later years as a result of diseases associated with aging. This can cause a loss of independence, isolation, and suffering. The Biogerontology Research Foundation, a United Kingdom-based nonprofit, is funding work to understand the molecular and cellular processes of aging and develop biotechnological interventions to halt or reverse damage from it. We spoke to Franco Cortese, deputy director of The Biogerontology Research Foundation, about a new report it’s issued that characterizes the longevity and geroscience landscape today, areas of research that hold promise, and why aging might best be thought of as a disease. https://www.youtube-nocookie.com/embed/Sn6mUtc_vjY 1117 2024-08-30T02:04:42.000Z 2026-10-22T19:04:38.889Z https://longevityharbor.com/en/watch/SpP8m98b0W4 Podcast description: rapamycin, aging biology and the Dog Aging Project with Dr. Matt Kaeberlein https://i.ytimg.com/vi/SpP8m98b0W4/hqdefault.jpg In this described episode, host Nicole Doran speaks with aging biologist Dr. Matt Kaeberlein about rapamycin, an mTOR inhibitor that has extended lifespan in animals, and about the Dog Aging Project, a large study testing rapamycin in companion dogs. https://www.youtube-nocookie.com/embed/SpP8m98b0W4 5684 2026-03-10T11:00:57.000Z 2026-10-23T02:11:37.326Z https://longevityharbor.com/de/watch/SpP8m98b0W4 Podcast-Beschreibung: Rapamycin, Alternsbiologie und das Dog Aging Project mit Dr. Matt Kaeberlein https://i.ytimg.com/vi/SpP8m98b0W4/hqdefault.jpg In dieser beschriebenen Episode spricht Gastgeberin Nicole Doran mit dem Alternsbiologen Dr. Matt Kaeberlein über Rapamycin, einen mTOR-Hemmer, der in Tieren die Lebensspanne verlängert hat, und über das Dog Aging Project, eine große Studie, die Rapamycin bei Begleithunden testet. https://www.youtube-nocookie.com/embed/SpP8m98b0W4 5684 2026-03-10T11:00:57.000Z 2026-10-23T02:11:37.326Z https://longevityharbor.com/en/watch/Sqg-_VbNewI How Menopause Hijacks Your Sleep: Circadian Rhythm, Melatonin & 'Simple' Fixes https://i.ytimg.com/vi/Sqg-_VbNewI/hqdefault.jpg I’m Lauren Chiren, CEO of Women of a Certain Stage and your guide to mastering menopause. Today I’m thrilled to welcome sleep scientist Dr Katharina “Kat” Koltermann to unpack why so many of us struggle to rest during perimenopause and beyond. As a GP and certified menopause strategist, I know that disturbed sleep worsens hot flushes, mood swings, circadian rhythm and metabolic changes. Kat shares evidence-based insights on how ageing eyes and reduced daytime blue light weaken your circadian rhythm, why melatonin is a timing signal—not a sedative—and which lifestyle “time-cues” reset your body clock. You’ll discover why the pressure to “must sleep” backfires and how morning light exposure, strategic movement, balanced meals and clearer home-life communication restore your rest. Join us for practical tips to reclaim deep, restorative sleep at every stage of menopause. Core Takeaways Prioritise morning light to strengthen your circadian rhythm as lenses age and blue light perception drops. Melatonin signals help time sleep but aren’t a cure—get medically-graded doses and respect natural darkness. Drop the “must sleep” mindset: replace pressure with curiosity, self-compassion and flexible rituals. Design daytime cues—exercise timing, mealtimes, social connection—to support effortless night-time rest. Align home schedules through open communication so everyone’s sleep needs—from teens to partners—are honoured. [00:02:13] Sleep and aging challenges. [00:05:02] Sleep needs and individual rhythms. [00:08:48] Importance of sleep for interaction. [00:11:34] Exercise and sleep quality. [00:19:09] Control during menopause changes. [00:20:03] Thoughts and emotions at night. [00:25:00] Teenagers and sleep patterns. [00:27:35] Impact of sleep on performance. [00:32:30] Sleep duration and individual needs. [00:37:21] Don't worry about sleep. [00:38:15] Letting go of control. Connect with me and checkout menopause talks, training and toolkits https://www.womenofacertainstage.com/ Contact Dr Kat https://drkatsleep.com/m https://www.youtube-nocookie.com/embed/Sqg-_VbNewI 2368 2025-09-09T01:00:36.000Z 2026-10-22T19:21:25.239Z https://longevityharbor.com/de/watch/Sqg-_VbNewI How Menopause Hijacks Your Sleep: Circadian Rhythm, Melatonin & 'Simple' Fixes https://i.ytimg.com/vi/Sqg-_VbNewI/hqdefault.jpg I’m Lauren Chiren, CEO of Women of a Certain Stage and your guide to mastering menopause. Today I’m thrilled to welcome sleep scientist Dr Katharina “Kat” Koltermann to unpack why so many of us struggle to rest during perimenopause and beyond. As a GP and certified menopause strategist, I know that disturbed sleep worsens hot flushes, mood swings, circadian rhythm and metabolic changes. Kat shares evidence-based insights on how ageing eyes and reduced daytime blue light weaken your circadian rhythm, why melatonin is a timing signal—not a sedative—and which lifestyle “time-cues” reset your body clock. You’ll discover why the pressure to “must sleep” backfires and how morning light exposure, strategic movement, balanced meals and clearer home-life communication restore your rest. Join us for practical tips to reclaim deep, restorative sleep at every stage of menopause. Core Takeaways Prioritise morning light to strengthen your circadian rhythm as lenses age and blue light perception drops. Melatonin signals help time sleep but aren’t a cure—get medically-graded doses and respect natural darkness. Drop the “must sleep” mindset: replace pressure with curiosity, self-compassion and flexible rituals. Design daytime cues—exercise timing, mealtimes, social connection—to support effortless night-time rest. Align home schedules through open communication so everyone’s sleep needs—from teens to partners—are honoured. [00:02:13] Sleep and aging challenges. [00:05:02] Sleep needs and individual rhythms. [00:08:48] Importance of sleep for interaction. [00:11:34] Exercise and sleep quality. [00:19:09] Control during menopause changes. [00:20:03] Thoughts and emotions at night. [00:25:00] Teenagers and sleep patterns. [00:27:35] Impact of sleep on performance. [00:32:30] Sleep duration and individual needs. [00:37:21] Don't worry about sleep. [00:38:15] Letting go of control. Connect with me and checkout menopause talks, training and toolkits https://www.womenofacertainstage.com/ Contact Dr Kat https://drkatsleep.com/m https://www.youtube-nocookie.com/embed/Sqg-_VbNewI 2368 2025-09-09T01:00:36.000Z 2026-10-22T19:21:25.239Z https://longevityharbor.com/en/watch/SwvkIrfM1rY Video description: sleep, circadian clock and metabolism claims for people over 50 https://i.ytimg.com/vi/SwvkIrfM1rY/hqdefault.jpg The description presents a long-form video on deep sleep after 50, covering the circadian clock, brain waste clearance, insulin resistance, body temperature, supplements and a wind-down routine. All details come from the description only; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/SwvkIrfM1rY 6030 2026-02-24T03:30:19.000Z 2026-10-23T02:20:46.686Z https://longevityharbor.com/de/watch/SwvkIrfM1rY Videobeschreibung: Schlaf-, Uhr- und Stoffwechselaussagen für Menschen über 50 https://i.ytimg.com/vi/SwvkIrfM1rY/hqdefault.jpg Die Beschreibung stellt ein Langvideo über Tiefschlaf nach 50 vor: circadiane Uhr, Abfallentsorgung im Gehirn, Insulinresistenz, Körpertemperatur, Nahrungsergänzung und ein Abendritual. Alle Angaben stammen nur aus der Beschreibung; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/SwvkIrfM1rY 6030 2026-02-24T03:30:19.000Z 2026-10-23T02:20:46.686Z https://longevityharbor.com/en/watch/T-MFBC43DkM Can Sound Influence Your DNA? | Vedic Chanting & Epigenetics | The Cosmic Code Ep. 16 https://i.ytimg.com/vi/T-MFBC43DkM/hqdefault.jpg Can something as simple as sound influence what happens inside our cells? Your DNA contains the instructions for life—but not every gene is active all the time. Epigenetics helps explain how biological and environmental signals can influence gene regulation. Thousands of years ago, Vedic traditions placed extraordinary importance on mantra, sound and disciplined chanting. So could there be a connection? Not in the sense that chanting magically “rewrites” or activates hidden DNA. The science is much more nuanced. In Episode 16 of The Cosmic Code, we explore DNA, epigenetics, sound, chanting and Vedic traditions—separating what modern science actually demonstrates from what remains an intriguing question. Can vibration influence biology in ways we are only beginning to understand? 🌌 THE COSMIC CODE — EPISODE 16 #Epigenetics #DNA #VedicChanting #SanatanDharma #TheCosmicCode #SoundHealing #Mantra #VedicWisdom #Genetics #Neuroscience #AncientIndia #ScienceAndSpirituality https://www.youtube-nocookie.com/embed/T-MFBC43DkM 120 2026-09-20T06:22:14.000Z 2026-10-22T19:43:50.837Z https://longevityharbor.com/de/watch/T-MFBC43DkM Can Sound Influence Your DNA? | Vedic Chanting & Epigenetics | The Cosmic Code Ep. 16 https://i.ytimg.com/vi/T-MFBC43DkM/hqdefault.jpg Can something as simple as sound influence what happens inside our cells? Your DNA contains the instructions for life—but not every gene is active all the time. Epigenetics helps explain how biological and environmental signals can influence gene regulation. Thousands of years ago, Vedic traditions placed extraordinary importance on mantra, sound and disciplined chanting. So could there be a connection? Not in the sense that chanting magically “rewrites” or activates hidden DNA. The science is much more nuanced. In Episode 16 of The Cosmic Code, we explore DNA, epigenetics, sound, chanting and Vedic traditions—separating what modern science actually demonstrates from what remains an intriguing question. Can vibration influence biology in ways we are only beginning to understand? 🌌 THE COSMIC CODE — EPISODE 16 #Epigenetics #DNA #VedicChanting #SanatanDharma #TheCosmicCode #SoundHealing #Mantra #VedicWisdom #Genetics #Neuroscience #AncientIndia #ScienceAndSpirituality https://www.youtube-nocookie.com/embed/T-MFBC43DkM 120 2026-09-20T06:22:14.000Z 2026-10-22T19:43:50.837Z https://longevityharbor.com/en/watch/T-dr22oOe9g Unlock the Benefits of Intermittent Fasting: Improved Health, Focus, and Longevity https://i.ytimg.com/vi/T-dr22oOe9g/hqdefault.jpg Intermittent fasting is more than just a trend—it’s a science-backed lifestyle that can transform your health. ⏱️ In this video, discover how fasting supports weight management, sharpens mental clarity, balances hormones, and even promotes longevity. Whether you're a beginner or exploring new fasting windows, learn how to get started safely and effectively. #IntermittentFasting #FastingBenefits #LongevityTips #FocusAndEnergy #HealthyLifestyle #WellnessHabits #FastingForHealth https://www.youtube-nocookie.com/embed/T-dr22oOe9g 93 2025-07-18T09:42:09.000Z 2026-10-22T19:54:17.029Z https://longevityharbor.com/de/watch/T-dr22oOe9g Unlock the Benefits of Intermittent Fasting: Improved Health, Focus, and Longevity https://i.ytimg.com/vi/T-dr22oOe9g/hqdefault.jpg Intermittent fasting is more than just a trend—it’s a science-backed lifestyle that can transform your health. ⏱️ In this video, discover how fasting supports weight management, sharpens mental clarity, balances hormones, and even promotes longevity. Whether you're a beginner or exploring new fasting windows, learn how to get started safely and effectively. #IntermittentFasting #FastingBenefits #LongevityTips #FocusAndEnergy #HealthyLifestyle #WellnessHabits #FastingForHealth https://www.youtube-nocookie.com/embed/T-dr22oOe9g 93 2025-07-18T09:42:09.000Z 2026-10-22T19:54:17.029Z https://longevityharbor.com/en/watch/T6con3CpGKI NMN in humans: trials measured aerobic capacity, NAD⁺ and muscle function, not lifespan https://i.ytimg.com/vi/T6con3CpGKI/hqdefault.jpg The description says NMN 'reverses aging' claims come from mice; human trials measured aerobic capacity, blood NAD⁺ and muscle function, and no trial has tested whether NMN extends lifespan. https://www.youtube-nocookie.com/embed/T6con3CpGKI 326 2026-09-08T17:10:20.000Z 2026-10-22T22:23:59.259Z https://longevityharbor.com/de/watch/T6con3CpGKI NMN beim Menschen: Studien maßen aerobe Kapazität, NAD⁺ und Muskelfunktion, nicht Lebensspanne https://i.ytimg.com/vi/T6con3CpGKI/hqdefault.jpg Laut Beschreibung stammen Aussagen, NMN 'verjünge', aus Mäusen; Humanstudien maßen aerobe Kapazität, NAD⁺ im Blut und Muskelfunktion, und keine Studie hat geprüft, ob NMN die Lebensspanne verlängert. https://www.youtube-nocookie.com/embed/T6con3CpGKI 326 2026-09-08T17:10:20.000Z 2026-10-22T22:23:59.259Z https://longevityharbor.com/en/watch/T8HAF6C4wWo Video description on nutrition from age 60, protein, exercise and drinking https://i.ytimg.com/vi/T8HAF6C4wWo/hqdefault.jpg The description says body changes often begin around age 40 or 50, and presents protein, movement and strength training as ways to help stay fit and vital in older age. It also names important nutrients, underestimated muscle loss and low drinking among older people as topics. https://www.youtube-nocookie.com/embed/T8HAF6C4wWo 2151 2026-03-07T06:08:32.000Z 2026-10-23T02:12:11.881Z https://longevityharbor.com/de/watch/T8HAF6C4wWo Videobeschreibung zu Ernährung ab 60, Eiweiß, Bewegung und Trinken https://i.ytimg.com/vi/T8HAF6C4wWo/hqdefault.jpg Die Beschreibung sagt, dass körperliche Veränderungen oft schon ab 40 oder 50 beginnen, und nennt Eiweiß, Bewegung und Krafttraining als Möglichkeiten, auch im Alter fit und vital zu bleiben. Außerdem nennt sie wichtige Nährstoffe, unterschätzten Muskelabbau und zu wenig Trinken bei vielen älteren Menschen als Themen. https://www.youtube-nocookie.com/embed/T8HAF6C4wWo 2151 2026-03-07T06:08:32.000Z 2026-10-23T02:12:11.881Z https://longevityharbor.com/en/watch/TDw7E6jSVKE Mouse study: calorie restriction, fasting and genetics in lifespan https://i.ytimg.com/vi/TDw7E6jSVKE/hqdefault.jpg In genetically diverse mice, calorie restriction and intermittent fasting extended lifespan in proportion to how much intake fell, but genetics influenced longevity more than diet, and stress resilience and immune health predicted long life better than metabolism. https://www.youtube-nocookie.com/embed/TDw7E6jSVKE 445 2026-02-08T00:38:22.000Z 2026-10-23T02:36:28.320Z https://longevityharbor.com/de/watch/TDw7E6jSVKE Mausstudie: Kalorienrestriktion, Fasten und Genetik bei Lebensspanne https://i.ytimg.com/vi/TDw7E6jSVKE/hqdefault.jpg Bei genetisch vielfältigen Mäusen verlängerten Kalorienrestriktion und intermittierendes Fasten die Lebensspanne im Verhältnis zur verringerten Aufnahme; doch Genetik beeinflusste die Langlebigkeit stärker als die Ernährung, und Stressresistenz und Immun Gesundheit sagten ein langes Leben besser voraus als der Stoffwechsel. https://www.youtube-nocookie.com/embed/TDw7E6jSVKE 445 2026-02-08T00:38:22.000Z 2026-10-23T02:36:28.320Z https://longevityharbor.com/en/watch/THexbtL8LHc Video description: smartphones, artificial light and circadian rhythm https://i.ytimg.com/vi/THexbtL8LHc/hqdefault.jpg The description says this OXYZEN Health Intelligence episode explores how screens, artificial light and late-night stimulation may disrupt sleep, melatonin, nervous-system recovery, metabolism, hormones and circadian rhythm. It presents topics and questions, not results. https://www.youtube-nocookie.com/embed/THexbtL8LHc 518 2026-05-14T11:03:20.000Z 2026-10-23T01:04:43.623Z https://longevityharbor.com/de/watch/THexbtL8LHc Videobeschreibung: Smartphones, künstliches Licht und circadianer Rhythmus https://i.ytimg.com/vi/THexbtL8LHc/hqdefault.jpg Laut Beschreibung untersucht diese Folge von OXYZEN Health Intelligence, wie Bildschirme, künstliches Licht und abendliche Stimulation Schlaf, Melatonin, Erholung des Nervensystems, Stoffwechsel, Hormone und den circadianen Rhythmus stören könnten. Sie nennt Themen und Fragen, keine Ergebnisse. https://www.youtube-nocookie.com/embed/THexbtL8LHc 518 2026-05-14T11:03:20.000Z 2026-10-23T01:04:43.623Z https://longevityharbor.com/en/watch/TKveJkb_BTc The Latest in Rapamycin Research in Humans (15 Longevity Studies) https://i.ytimg.com/vi/TKveJkb_BTc/hqdefault.jpg Not many compounds actually extend life in healthy animals, but rapamycin is indeed one of them. Researchers report that its mechanism of action, the mechanistic target of rapamycin (known as mTOR), is linked to five of twelve hallmarks of aging. I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the affiliate links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 ProHealth 15% Discount Code: MYNMN (https://www.prohealth.com/) Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Youth & Earth 15% Discount Code: MYNMN (https://youthandearth.com?sca_ref=3766764.knrWl4O3cB) Please note that the links above are affiliate links, which means that if you use the code, I will receive a small commission, and if you do, may I say many thanks I advance for your support. My Current Anti-Aging Protocol: • 1.5 grams of an NADBooster (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • Quercetin & Fisetin Periodic Dosing (https://bit.ly/3mw1IgN) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator (https://bit.ly/3MyfA4J) • 600mg DIM (https://bit.ly/3ZX9NsG) • 800mg GlyNAC (https://shorturl.ac/7b75r) • 5mg of Cre https://www.youtube-nocookie.com/embed/TKveJkb_BTc 267 2024-03-19T18:00:29.000Z 2026-10-22T19:32:36.485Z https://longevityharbor.com/de/watch/TKveJkb_BTc The Latest in Rapamycin Research in Humans (15 Longevity Studies) https://i.ytimg.com/vi/TKveJkb_BTc/hqdefault.jpg Not many compounds actually extend life in healthy animals, but rapamycin is indeed one of them. Researchers report that its mechanism of action, the mechanistic target of rapamycin (known as mTOR), is linked to five of twelve hallmarks of aging. I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the affiliate links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 ProHealth 15% Discount Code: MYNMN (https://www.prohealth.com/) Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Youth & Earth 15% Discount Code: MYNMN (https://youthandearth.com?sca_ref=3766764.knrWl4O3cB) Please note that the links above are affiliate links, which means that if you use the code, I will receive a small commission, and if you do, may I say many thanks I advance for your support. My Current Anti-Aging Protocol: • 1.5 grams of an NADBooster (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • Quercetin & Fisetin Periodic Dosing (https://bit.ly/3mw1IgN) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator (https://bit.ly/3MyfA4J) • 600mg DIM (https://bit.ly/3ZX9NsG) • 800mg GlyNAC (https://shorturl.ac/7b75r) • 5mg of Cre https://www.youtube-nocookie.com/embed/TKveJkb_BTc 267 2024-03-19T18:00:29.000Z 2026-10-22T19:32:36.485Z https://longevityharbor.com/en/watch/TLxIYdd_9M0 Video description: four daily habits and aging biology for staying functional into the 80s and 90s https://i.ytimg.com/vi/TLxIYdd_9M0/hqdefault.jpg The description says the episode reviews aging biology (DNA damage, telomeres, mitochondria, inflammation, senescent cells, epigenetics) and names four daily habits: movement, whole foods, stress reduction and quality sleep. It also mentions NAD supplements and calorie restriction, citing animal research on biological aging markers. https://www.youtube-nocookie.com/embed/TLxIYdd_9M0 93 2026-02-22T13:00:55.000Z 2026-10-23T02:26:06.386Z https://longevityharbor.com/de/watch/TLxIYdd_9M0 Videobeschreibung: vier Alltagsgewohnheiten und Alternsbiologie für Funktionsfähigkeit mit 80 und 90 https://i.ytimg.com/vi/TLxIYdd_9M0/hqdefault.jpg Laut Beschreibung behandelt die Folge die Alternsbiologie (DNA-Schäden, Telomere, Mitochondrien, Entzündung, seneszente Zellen, Epigenetik) und nennt vier Alltagsgewohnheiten: Bewegung, vollwertige Lebensmittel, Stressabbau und guter Schlaf. Zudem werden NAD-Präparate und Kalorienrestriktion erwähnt, mit Tierforschung zu Markern des biologischen Alterns. https://www.youtube-nocookie.com/embed/TLxIYdd_9M0 93 2026-02-22T13:00:55.000Z 2026-10-23T02:26:06.386Z https://longevityharbor.com/en/watch/TT5ig1EiIfQ The best foods to fight inflammation this spring | Prof. Tim Spector and Dr. Federica Amati https://i.ytimg.com/vi/TT5ig1EiIfQ/hqdefault.jpg 🥑 Make smarter food choices. Become a member at http://zoe.com Spring is the perfect time to shake up your routine. In this episode, Professor Tim Spector and Dr. Federica Amati reveal seven delicious, science-backed foods that help cool the flame of chronic inflammation. Whether you're dealing with bloating, aching joints, or low energy, this episode is packed with easy, gut-friendly tips to help you feel your best this season. Tim and Federica begin by explaining what inflammation really is and when it becomes a problem. Then, they’ll introduce seven anti-inflammatory foods that are as powerful as they are delicious. From cruciferous vegetables to fermented surprises, these everyday ingredients can help you build a more resilient, healing diet. Finally, they offer a roadmap for long-term change. Tim and Fed each share one small but powerful shift to reduce inflammation over four timelines - what you can do today, this week, this month, and throughout the year - to create habits that truly stick. 🌱 Try our new plant based wholefood supplement - Daily30: https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=podcast_platform&utm_campaign=d30 Follow ZOE on Instagram | https://www.instagram.com/zoe/ Timecodes 00:00 Worried about inflammation? 01:55 Listener Q&A 03:18 Is inflammation always bad? 07:28 Can inflammation cause cancer? 11:35 Does inflammation speed up aging? 13:08 How does food impact inflammation? 17:25 Gut health and inflammation 21:12 Do detox juice cleanses work? 23:25 Food #1: Green powerhouse 26:20 Food #2: As effective as ibuprofen? 28:43 Food #3: Surprising sweet treat 33:19 Food #4: Small but mighty 37:11 Food #5: Spice with a health kick 41:59 Food #6: Best berries 45:35 Food #7: Essential ferments 49:07 Start reducing inflammation today 50:55 Reduce inflammation over 30 days 53:04 How to reduce inflammation over a year 📚Books by our ZOE Scientists The Food For Life Cookbook | https://amzn.to/4amfIMX Every Body Should Know This by Dr Federica Amati | https://amzn.to/4blJsLg F https://www.youtube-nocookie.com/embed/TT5ig1EiIfQ 3741 2025-04-17T15:06:00.000Z 2026-10-22T19:43:45.314Z https://longevityharbor.com/de/watch/TT5ig1EiIfQ The best foods to fight inflammation this spring | Prof. Tim Spector and Dr. Federica Amati https://i.ytimg.com/vi/TT5ig1EiIfQ/hqdefault.jpg 🥑 Make smarter food choices. Become a member at http://zoe.com Spring is the perfect time to shake up your routine. In this episode, Professor Tim Spector and Dr. Federica Amati reveal seven delicious, science-backed foods that help cool the flame of chronic inflammation. Whether you're dealing with bloating, aching joints, or low energy, this episode is packed with easy, gut-friendly tips to help you feel your best this season. Tim and Federica begin by explaining what inflammation really is and when it becomes a problem. Then, they’ll introduce seven anti-inflammatory foods that are as powerful as they are delicious. From cruciferous vegetables to fermented surprises, these everyday ingredients can help you build a more resilient, healing diet. Finally, they offer a roadmap for long-term change. Tim and Fed each share one small but powerful shift to reduce inflammation over four timelines - what you can do today, this week, this month, and throughout the year - to create habits that truly stick. 🌱 Try our new plant based wholefood supplement - Daily30: https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=podcast_platform&utm_campaign=d30 Follow ZOE on Instagram | https://www.instagram.com/zoe/ Timecodes 00:00 Worried about inflammation? 01:55 Listener Q&A 03:18 Is inflammation always bad? 07:28 Can inflammation cause cancer? 11:35 Does inflammation speed up aging? 13:08 How does food impact inflammation? 17:25 Gut health and inflammation 21:12 Do detox juice cleanses work? 23:25 Food #1: Green powerhouse 26:20 Food #2: As effective as ibuprofen? 28:43 Food #3: Surprising sweet treat 33:19 Food #4: Small but mighty 37:11 Food #5: Spice with a health kick 41:59 Food #6: Best berries 45:35 Food #7: Essential ferments 49:07 Start reducing inflammation today 50:55 Reduce inflammation over 30 days 53:04 How to reduce inflammation over a year 📚Books by our ZOE Scientists The Food For Life Cookbook | https://amzn.to/4amfIMX Every Body Should Know This by Dr Federica Amati | https://amzn.to/4blJsLg F https://www.youtube-nocookie.com/embed/TT5ig1EiIfQ 3741 2025-04-17T15:06:00.000Z 2026-10-22T19:43:45.314Z https://longevityharbor.com/en/watch/TVTclpwn0WY Geroscience: An Evolving Field https://i.ytimg.com/vi/TVTclpwn0WY/hqdefault.jpg Geroscience: An Evolving Field with Steve Kritchevsky, PhD, MSPH (Wake Forest) and Discussant, Lis Nielsen, PhD (NIA). https://www.youtube-nocookie.com/embed/TVTclpwn0WY 3085 2022-06-17T22:08:39.000Z 2026-10-22T17:43:40.196Z https://longevityharbor.com/de/watch/TVTclpwn0WY Geroscience: An Evolving Field https://i.ytimg.com/vi/TVTclpwn0WY/hqdefault.jpg Geroscience: An Evolving Field with Steve Kritchevsky, PhD, MSPH (Wake Forest) and Discussant, Lis Nielsen, PhD (NIA). https://www.youtube-nocookie.com/embed/TVTclpwn0WY 3085 2022-06-17T22:08:39.000Z 2026-10-22T17:43:40.196Z https://longevityharbor.com/en/watch/TdmSyMsK7b0 The Epigenetic Clock https://i.ytimg.com/vi/TdmSyMsK7b0/hqdefault.jpg The Epigenetic Clock https://www.youtube-nocookie.com/embed/TdmSyMsK7b0 394 2026-01-06T04:11:16.000Z 2026-10-22T19:21:27.787Z https://longevityharbor.com/de/watch/TdmSyMsK7b0 The Epigenetic Clock https://i.ytimg.com/vi/TdmSyMsK7b0/hqdefault.jpg The Epigenetic Clock https://www.youtube-nocookie.com/embed/TdmSyMsK7b0 394 2026-01-06T04:11:16.000Z 2026-10-22T19:21:27.787Z https://longevityharbor.com/en/watch/TepHG3P1Yow Nephrologist's video description on fasting, weight loss and longevity https://i.ytimg.com/vi/TepHG3P1Yow/hqdefault.jpg The description says nephrologist Dr. Jason Fung presents fasting as more than calorie cutting, linking it to insulin, stored fat, type 2 diabetes, autophagy and longevity, and also addresses muscle-loss concerns. https://www.youtube-nocookie.com/embed/TepHG3P1Yow 2438 2026-09-02T12:00:01.000Z 2026-10-22T22:33:07.375Z https://longevityharbor.com/de/watch/TepHG3P1Yow Nephrologe in Videobeschreibung zu Fasten, Gewichtsverlust und Langlebigkeit https://i.ytimg.com/vi/TepHG3P1Yow/hqdefault.jpg Laut Beschreibung stellt der Nephrologe Dr. Jason Fung Fasten als mehr als Kalorienreduktion dar, verknüpft es mit Insulin, gespeichertem Fett, Typ-2-Diabetes, Autophagie und Langlebigkeit und geht auch auf Sorgen wegen Muskelverlusts ein. https://www.youtube-nocookie.com/embed/TepHG3P1Yow 2438 2026-09-02T12:00:01.000Z 2026-10-22T22:33:07.375Z https://longevityharbor.com/en/watch/Tk9K3QYsLnQ Neurologist's Video Description: Muscle Strength, Strength Training and Brain Health https://i.ytimg.com/vi/Tk9K3QYsLnQ/hqdefault.jpg In this video description, neurologist Nikolai Grundhoff says he will explain why muscle strength matters for healthy aging and what strength training has to do with the brain. He says he will cover what science shows and why starting later in life can still be worthwhile. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/Tk9K3QYsLnQ 337 2026-10-13T15:00:39.000Z 2026-10-22T19:56:48.019Z https://longevityharbor.com/de/watch/Tk9K3QYsLnQ Video-Beschreibung eines Neurologen: Muskelkraft, Krafttraining und Gehirngesundheit https://i.ytimg.com/vi/Tk9K3QYsLnQ/hqdefault.jpg In dieser Video-Beschreibung kündigt der Neurologe Nikolai Grundhoff an, zu erklären, warum Muskelkraft für gesundes Altern wichtig ist und was Krafttraining mit dem Gehirn zu tun hat. Er will zeigen, was die Wissenschaft zeigt und warum ein späterer Einstieg sich noch lohnen kann. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/Tk9K3QYsLnQ 337 2026-10-13T15:00:39.000Z 2026-10-22T19:56:48.019Z https://longevityharbor.com/en/watch/Tm0f5iXMeso Wundermittel Sport: Körper, Geist und Gene profitieren von Bewegung | Quarks https://i.ytimg.com/vi/Tm0f5iXMeso/hqdefault.jpg Sport ist gesund, heißt es immer. Doch stimmt das? Tatsächlich entdecken Sportmediziner immer mehr Details, die zeigen: Regelmäßiger Sport ist sogar gesünder, als viele bislang dachten. Sport beeinflusst nicht nur Muskeln, Herz und Knochen, sondern auch unser Gehirn – und unsere Gene. Autor: Mike Schaefer --- Danke fürs Zuschauen! Hat dir das Video gefallen? Dann abonniere jetzt den einzigen offiziellen Quarks-Kanal auf YouTube: https://www.youtube.com/Quarks?sub_confirmation=1 Quarks auf Facebook: https://www.facebook.com/quarks.de/ Besuche auch: https://www.quarks.de Quarks auf Instagram: https://www.instagram.com/quarks.de/ https://www.instagram.com/beautyquarks/ Hier gelangst du zum Clip in der WDR-Mediathek: https://www1.wdr.de/mediathek/video/sendungen/quarks-und-co/video-wie-gesund-ist-sport-wirklich-104.html https://www.youtube-nocookie.com/embed/Tm0f5iXMeso 303 2018-07-12T15:00:03.000Z 2026-10-22T18:32:13.275Z https://longevityharbor.com/de/watch/Tm0f5iXMeso Wundermittel Sport: Körper, Geist und Gene profitieren von Bewegung | Quarks https://i.ytimg.com/vi/Tm0f5iXMeso/hqdefault.jpg Sport ist gesund, heißt es immer. Doch stimmt das? Tatsächlich entdecken Sportmediziner immer mehr Details, die zeigen: Regelmäßiger Sport ist sogar gesünder, als viele bislang dachten. Sport beeinflusst nicht nur Muskeln, Herz und Knochen, sondern auch unser Gehirn – und unsere Gene. Autor: Mike Schaefer --- Danke fürs Zuschauen! Hat dir das Video gefallen? Dann abonniere jetzt den einzigen offiziellen Quarks-Kanal auf YouTube: https://www.youtube.com/Quarks?sub_confirmation=1 Quarks auf Facebook: https://www.facebook.com/quarks.de/ Besuche auch: https://www.quarks.de Quarks auf Instagram: https://www.instagram.com/quarks.de/ https://www.instagram.com/beautyquarks/ Hier gelangst du zum Clip in der WDR-Mediathek: https://www1.wdr.de/mediathek/video/sendungen/quarks-und-co/video-wie-gesund-ist-sport-wirklich-104.html https://www.youtube-nocookie.com/embed/Tm0f5iXMeso 303 2018-07-12T15:00:03.000Z 2026-10-22T18:32:13.275Z https://longevityharbor.com/en/watch/TsyzxK0D11Y Parkinson's and Alzheimer's: The Gut-Brain Connection Explored with Dr. Julie Andersen https://i.ytimg.com/vi/TsyzxK0D11Y/hqdefault.jpg In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses her groundbreaking work on neurodegenerative diseases, focusing on Parkinson's and Alzheimer's. She explains how the field of geroscience is transforming our understanding of aging, revealing that common underlying processes in various diseases could lead to universal therapeutic approaches. Dr. Andersen dives into the gut-brain connection, highlighting how gut health significantly impacts brain aging and the progression of neurodegenerative diseases. She also emphasizes the importance of cellular senescence, a process where aging cells stop dividing, contributing to diseases like Alzheimer's. Her research explores innovative ways to slow or prevent these processes, paving the way for new treatments. The episode concludes with Dr. Andersen advocating for lifestyle interventions, particularly exercise, as powerful tools in preventing neurodegenerative diseases. She underscores the potential of personalized medicine in tailoring treatments to individual aging patterns, offering hope for more effective and targeted therapies. Episode highlights: Introduction: 00:00:00 Dementia as a side effect of aging: 00:06:00 Dementia prevalence in the population: 00:10:00 The environment and Alzheimer's disease: 00:15:00 Biological sex effect on Dementia  00:17:00 Ethnicity effect on Dementia  00:18:00 What to expect when you are diagnosed with Dementia 00:19:00 Biomarkers for Dementia 00:26:00 The connection between the hallmarks of aging and Dementia: 00:30:00  Exercise and Dementia: 00:34:00 disruption of REM sleep as an early sign of Parkinson's: 00:37:00 What is the current treatment for Parkinson's: 00:38:00 Cellular senescence and neurodegenerative diseases: 00:42:00 Beta amyloid plaques and Alzheimer's disease: 00:50:00 Autophagy and dementia: 01:00:00 What would you recommend to a person who like to live better and longer https://www.youtube-nocookie.com/embed/TsyzxK0D11Y 4441 2024-08-15T16:50:37.000Z 2026-10-22T19:04:38.531Z https://longevityharbor.com/de/watch/TsyzxK0D11Y Parkinson's and Alzheimer's: The Gut-Brain Connection Explored with Dr. Julie Andersen https://i.ytimg.com/vi/TsyzxK0D11Y/hqdefault.jpg In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses her groundbreaking work on neurodegenerative diseases, focusing on Parkinson's and Alzheimer's. She explains how the field of geroscience is transforming our understanding of aging, revealing that common underlying processes in various diseases could lead to universal therapeutic approaches. Dr. Andersen dives into the gut-brain connection, highlighting how gut health significantly impacts brain aging and the progression of neurodegenerative diseases. She also emphasizes the importance of cellular senescence, a process where aging cells stop dividing, contributing to diseases like Alzheimer's. Her research explores innovative ways to slow or prevent these processes, paving the way for new treatments. The episode concludes with Dr. Andersen advocating for lifestyle interventions, particularly exercise, as powerful tools in preventing neurodegenerative diseases. She underscores the potential of personalized medicine in tailoring treatments to individual aging patterns, offering hope for more effective and targeted therapies. Episode highlights: Introduction: 00:00:00 Dementia as a side effect of aging: 00:06:00 Dementia prevalence in the population: 00:10:00 The environment and Alzheimer's disease: 00:15:00 Biological sex effect on Dementia  00:17:00 Ethnicity effect on Dementia  00:18:00 What to expect when you are diagnosed with Dementia 00:19:00 Biomarkers for Dementia 00:26:00 The connection between the hallmarks of aging and Dementia: 00:30:00  Exercise and Dementia: 00:34:00 disruption of REM sleep as an early sign of Parkinson's: 00:37:00 What is the current treatment for Parkinson's: 00:38:00 Cellular senescence and neurodegenerative diseases: 00:42:00 Beta amyloid plaques and Alzheimer's disease: 00:50:00 Autophagy and dementia: 01:00:00 What would you recommend to a person who like to live better and longer https://www.youtube-nocookie.com/embed/TsyzxK0D11Y 4441 2024-08-15T16:50:37.000Z 2026-10-22T19:04:38.531Z https://longevityharbor.com/en/watch/U-zF56QPkkM Video description: rapamycin, mTOR and lifespan claims https://i.ytimg.com/vi/U-zF56QPkkM/hqdefault.jpg The description says the video covers rapamycin's effects on lifespan extension, mTOR pathways, longevity studies, benefits, risks and current research; it presents no results and calls itself educational only. https://www.youtube-nocookie.com/embed/U-zF56QPkkM 174 2025-12-25T21:34:36.000Z 2026-10-23T03:09:39.546Z https://longevityharbor.com/de/watch/U-zF56QPkkM Videobeschreibung: Rapamycin, mTOR und Lebensspannen-Aussagen https://i.ytimg.com/vi/U-zF56QPkkM/hqdefault.jpg Die Beschreibung nennt als Inhalt Rapamycins Wirkung auf die Lebensverlängerung, mTOR-Signalwege, Langlebigkeitsstudien, Nutzen, Risiken und aktuelle Forschung; Ergebnisse nennt sie nicht und bezeichnet sich nur als Bildungsinhalt. https://www.youtube-nocookie.com/embed/U-zF56QPkkM 174 2025-12-25T21:34:36.000Z 2026-10-23T03:09:39.546Z https://longevityharbor.com/en/watch/U0z4NvbZHm4 Video description: Sinclair episode on calorie restriction and fasting science https://i.ytimg.com/vi/U0z4NvbZHm4/hqdefault.jpg The description says this Lifespan episode has Dr. David Sinclair explore the science of calorie restriction and fasting, including human and animal studies on lifespan, metabolism and disease risk. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/U0z4NvbZHm4 4523 2026-06-25T11:40:36.000Z 2026-10-22T23:48:46.466Z https://longevityharbor.com/de/watch/U0z4NvbZHm4 Videobeschreibung: Sinclair-Episode zur Wissenschaft von Kalorienrestriktion und Fasten https://i.ytimg.com/vi/U0z4NvbZHm4/hqdefault.jpg Laut Beschreibung untersucht Dr. David Sinclair in dieser Lifespan-Episode die Wissenschaft von Kalorienrestriktion und Fasten, einschließlich Human- und Tierstudien zu Lebensspanne, Stoffwechsel und Krankheitsrisiko. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/U0z4NvbZHm4 4523 2026-06-25T11:40:36.000Z 2026-10-22T23:48:46.466Z https://longevityharbor.com/en/watch/U5ORO0IN_IM What are the hallmarks of aging? https://i.ytimg.com/vi/U5ORO0IN_IM/hqdefault.jpg What are the hallmarks of aging? Why is it over time cells become less functional? This video will introduce you to the nine different hallmarks of aging including the primary causes of damage, the responses to the damage and the systemic hallmarks. The review paper; https://www.cell.com/abstract/S0092-8674(13)00645-4 Blog; asheekeyscienceblog.com https://www.youtube-nocookie.com/embed/U5ORO0IN_IM 277 2019-06-24T10:25:42.000Z 2026-10-22T17:43:40.144Z https://longevityharbor.com/de/watch/U5ORO0IN_IM What are the hallmarks of aging? https://i.ytimg.com/vi/U5ORO0IN_IM/hqdefault.jpg What are the hallmarks of aging? Why is it over time cells become less functional? This video will introduce you to the nine different hallmarks of aging including the primary causes of damage, the responses to the damage and the systemic hallmarks. The review paper; https://www.cell.com/abstract/S0092-8674(13)00645-4 Blog; asheekeyscienceblog.com https://www.youtube-nocookie.com/embed/U5ORO0IN_IM 277 2019-06-24T10:25:42.000Z 2026-10-22T17:43:40.144Z https://longevityharbor.com/en/watch/UC0uLi2shjw Does the Fasting trend really help you live longer? #health #longevity #trending #snarkynp #medical https://i.ytimg.com/vi/UC0uLi2shjw/hqdefault.jpg Does the Fasting trend really help you live longer? #health #longevity #trending #snarkynp #medical https://www.youtube-nocookie.com/embed/UC0uLi2shjw 176 2026-03-13T01:46:40.000Z 2026-10-22T18:54:06.926Z https://longevityharbor.com/de/watch/UC0uLi2shjw Does the Fasting trend really help you live longer? #health #longevity #trending #snarkynp #medical https://i.ytimg.com/vi/UC0uLi2shjw/hqdefault.jpg Does the Fasting trend really help you live longer? #health #longevity #trending #snarkynp #medical https://www.youtube-nocookie.com/embed/UC0uLi2shjw 176 2026-03-13T01:46:40.000Z 2026-10-22T18:54:06.926Z https://longevityharbor.com/en/watch/UDiIliFKPZ4 Podcast description: caloric restriction, metabolism and aging with Dr. Rozalyn Anderson https://i.ytimg.com/vi/UDiIliFKPZ4/hqdefault.jpg In this podcast description, Dr. Rozalyn Anderson discusses caloric restriction as the gold standard for studying longevity interventions, metabolism's role in aging, and geroprotectors such as rapamycin; the description also mentions human trials like CALERIE and methylation clocks. https://www.youtube-nocookie.com/embed/UDiIliFKPZ4 1853 2025-12-01T17:00:51.000Z 2026-10-23T03:22:50.738Z https://longevityharbor.com/de/watch/UDiIliFKPZ4 Podcast-Beschreibung: Kalorienrestriktion, Stoffwechsel und Altern mit Dr. Rozalyn Anderson https://i.ytimg.com/vi/UDiIliFKPZ4/hqdefault.jpg In dieser Podcast-Beschreibung spricht Dr. Rozalyn Anderson über Kalorienrestriktion als Goldstandard für die Erforschung von Langlebigkeits-Interventionen, die Rolle des Stoffwechsels beim Altern und Geroprotektoren wie Rapamycin; zudem werden humane Studien wie CALERIE und Methylierungsuhren erwähnt. https://www.youtube-nocookie.com/embed/UDiIliFKPZ4 1853 2025-12-01T17:00:51.000Z 2026-10-23T03:22:50.738Z https://longevityharbor.com/en/watch/UEzbbvHKoZ4 How Important Is Sleep and Circadian Rhythm for Longevity https://i.ytimg.com/vi/UEzbbvHKoZ4/hqdefault.jpg In this video, we explore the importance of sleep and circadian rhythm for longevity. Learn how these factors can impact your overall health and lifespan. #peptides #doctor #sleepsolution #circadianrhythm #circadian #circadianrhythms #longevity #healthspan https://www.youtube-nocookie.com/embed/UEzbbvHKoZ4 577 2025-09-24T16:00:54.000Z 2026-10-22T19:21:25.249Z https://longevityharbor.com/de/watch/UEzbbvHKoZ4 How Important Is Sleep and Circadian Rhythm for Longevity https://i.ytimg.com/vi/UEzbbvHKoZ4/hqdefault.jpg In this video, we explore the importance of sleep and circadian rhythm for longevity. Learn how these factors can impact your overall health and lifespan. #peptides #doctor #sleepsolution #circadianrhythm #circadian #circadianrhythms #longevity #healthspan https://www.youtube-nocookie.com/embed/UEzbbvHKoZ4 577 2025-09-24T16:00:54.000Z 2026-10-22T19:21:25.249Z https://longevityharbor.com/en/watch/UJzokhSAxf8 The Future of Aging: Ancient Secrets for Healthy Longevity | Dr. Anurag Singh https://i.ytimg.com/vi/UJzokhSAxf8/hqdefault.jpg Dr. Motley welcomes Dr. Anurag Singh, MD, medical researcher and chief medical officer at Timeline, for a conversation about the future of longevity and healthspan. We all want to age well with our minds and mobility intact. Dr. Singh gives us the latest research on reversing the effects of aging; turns out it’s all based on ancient, natural principles. * Learn more about Urolithin A supplementation HERE: https://shorturl.at/0ehK3 and use promo code DRMOTLEY for 10% off! * This episode is brought to you by Zona Plus. If you’re looking for a safe, easy way to improve your heart health, check out zona.com and use code DRMOTLEY for $100 off the Zona Plus device! ====================== Want more of The Ancient Health Podcast? Subscribe to Doctor Motley's channel. Instagram: https://www.instagram.com/doctormotley Twitter: https://www.x.com/Doctormotley Facebook: https://www.facebook.com/doctormotley/ Tik-Tok: https://www.tiktok.com/@doctormotley Website: https://doctormotley.com ==================== Show Notes: Explore Dr. Singh’s studies on Urolithin A Hallmarks of Aging: An expanded Universe: https://www.cell.com/cell/fulltext/S0092-8674(22)01377-0 The mitophagy activator Urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans: https://www.nature.com/articles/s42255-019-0073-4 https://www.youtube-nocookie.com/embed/UJzokhSAxf8 2262 2025-02-25T12:00:46.000Z 2026-10-22T19:04:37.495Z https://longevityharbor.com/de/watch/UJzokhSAxf8 The Future of Aging: Ancient Secrets for Healthy Longevity | Dr. Anurag Singh https://i.ytimg.com/vi/UJzokhSAxf8/hqdefault.jpg Dr. Motley welcomes Dr. Anurag Singh, MD, medical researcher and chief medical officer at Timeline, for a conversation about the future of longevity and healthspan. We all want to age well with our minds and mobility intact. Dr. Singh gives us the latest research on reversing the effects of aging; turns out it’s all based on ancient, natural principles. * Learn more about Urolithin A supplementation HERE: https://shorturl.at/0ehK3 and use promo code DRMOTLEY for 10% off! * This episode is brought to you by Zona Plus. If you’re looking for a safe, easy way to improve your heart health, check out zona.com and use code DRMOTLEY for $100 off the Zona Plus device! ====================== Want more of The Ancient Health Podcast? Subscribe to Doctor Motley's channel. Instagram: https://www.instagram.com/doctormotley Twitter: https://www.x.com/Doctormotley Facebook: https://www.facebook.com/doctormotley/ Tik-Tok: https://www.tiktok.com/@doctormotley Website: https://doctormotley.com ==================== Show Notes: Explore Dr. Singh’s studies on Urolithin A Hallmarks of Aging: An expanded Universe: https://www.cell.com/cell/fulltext/S0092-8674(22)01377-0 The mitophagy activator Urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans: https://www.nature.com/articles/s42255-019-0073-4 https://www.youtube-nocookie.com/embed/UJzokhSAxf8 2262 2025-02-25T12:00:46.000Z 2026-10-22T19:04:37.495Z https://longevityharbor.com/en/watch/ULtchC33bNE USC|UCLA Geroscience Meeting Day 1 Morning https://i.ytimg.com/vi/ULtchC33bNE/hqdefault.jpg USC|UCLA Geroscience Meeting: Integrating Social and Biological Hallmarks of Aging Day 1 Morning GLP-1 Drugs, Population Health and Aging: A New Frontier? - Jennifer Dowd (00:00:42) Immune Cell Clonality and Morality: The Health and Retirement Study - Bharat Thyagarajan (00:28:28) Assessment of ageing using global mass-spectrometry based metabolomics in a large longitudinal cross-cohort study (00:57:00) Neuroendocrine markers of cognitive aging: from mid to late life - Teal Eich (01:31:10) Pathways linking the dramatic changes seen in autonomic activity to changes in amyloid-beta levels from ages 20 to 60 (01:59:20) Targeting Aging Biology for Alzheimer's Disease Prevention and Treatment - Mitzi Gonzalez (02:32:10) https://www.youtube-nocookie.com/embed/ULtchC33bNE 10228 2025-04-16T20:58:56.000Z 2026-10-22T18:32:11.539Z https://longevityharbor.com/de/watch/ULtchC33bNE USC|UCLA Geroscience Meeting Day 1 Morning https://i.ytimg.com/vi/ULtchC33bNE/hqdefault.jpg USC|UCLA Geroscience Meeting: Integrating Social and Biological Hallmarks of Aging Day 1 Morning GLP-1 Drugs, Population Health and Aging: A New Frontier? - Jennifer Dowd (00:00:42) Immune Cell Clonality and Morality: The Health and Retirement Study - Bharat Thyagarajan (00:28:28) Assessment of ageing using global mass-spectrometry based metabolomics in a large longitudinal cross-cohort study (00:57:00) Neuroendocrine markers of cognitive aging: from mid to late life - Teal Eich (01:31:10) Pathways linking the dramatic changes seen in autonomic activity to changes in amyloid-beta levels from ages 20 to 60 (01:59:20) Targeting Aging Biology for Alzheimer's Disease Prevention and Treatment - Mitzi Gonzalez (02:32:10) https://www.youtube-nocookie.com/embed/ULtchC33bNE 10228 2025-04-16T20:58:56.000Z 2026-10-22T18:32:11.539Z https://longevityharbor.com/en/watch/UMcUISiAvGY Naked mole-rat longevity: modified cGAS, hyaluronic acid and mitochondria https://i.ytimg.com/vi/UMcUISiAvGY/hqdefault.jpg The description says naked mole-rats show negligible senescence, with mortality risk not rising significantly with age, and links this to a modified cGAS enzyme, abundant high-molecular-weight hyaluronic acid and efficient mitochondria. https://www.youtube-nocookie.com/embed/UMcUISiAvGY 383 2026-04-08T15:00:53.000Z 2026-10-23T01:37:56.709Z https://longevityharbor.com/de/watch/UMcUISiAvGY Nacktmull-Langlebigkeit: verändertes cGAS, Hyaluronsäure und Mitochondrien https://i.ytimg.com/vi/UMcUISiAvGY/hqdefault.jpg Die Beschreibung besagt, dass Nacktmulle eine vernachlässigbare Seneszenz zeigen, wobei das Sterberisiko mit dem Alter nicht deutlich steigt, und führt dies auf ein verändertes cGAS-Enzym, reichlich hochmolekulare Hyaluronsäure und effiziente Mitochondrien zurück. https://www.youtube-nocookie.com/embed/UMcUISiAvGY 383 2026-04-08T15:00:53.000Z 2026-10-23T01:37:56.709Z https://longevityharbor.com/en/watch/UN2UrL1oJCM The Truth About Fasting & Weight Loss in Menopause https://i.ytimg.com/vi/UN2UrL1oJCM/hqdefault.jpg Fasting isn’t a long-term weight loss solution—especially during menopause. Learn how it impacts inflammation, insulin, and muscle loss, and why scale numbers and BMI don’t reflect your true health. https://www.youtube-nocookie.com/embed/UN2UrL1oJCM 94 2025-07-11T16:00:52.000Z 2026-10-22T19:54:16.688Z https://longevityharbor.com/de/watch/UN2UrL1oJCM The Truth About Fasting & Weight Loss in Menopause https://i.ytimg.com/vi/UN2UrL1oJCM/hqdefault.jpg Fasting isn’t a long-term weight loss solution—especially during menopause. Learn how it impacts inflammation, insulin, and muscle loss, and why scale numbers and BMI don’t reflect your true health. https://www.youtube-nocookie.com/embed/UN2UrL1oJCM 94 2025-07-11T16:00:52.000Z 2026-10-22T19:54:16.688Z https://longevityharbor.com/en/watch/UNg93xWEafE NMN vs NAD: Which is Better for Your Brain? #nmn #nad #supplements #robertlove https://i.ytimg.com/vi/UNg93xWEafE/hqdefault.jpg NMN vs NAD: Which is Better for Your Brain? #nmn #nad #supplements #robertlove https://www.youtube-nocookie.com/embed/UNg93xWEafE 121 2026-01-24T03:00:37.000Z 2026-10-22T17:43:42.564Z https://longevityharbor.com/de/watch/UNg93xWEafE NMN vs NAD: Which is Better for Your Brain? #nmn #nad #supplements #robertlove https://i.ytimg.com/vi/UNg93xWEafE/hqdefault.jpg NMN vs NAD: Which is Better for Your Brain? #nmn #nad #supplements #robertlove https://www.youtube-nocookie.com/embed/UNg93xWEafE 121 2026-01-24T03:00:37.000Z 2026-10-22T17:43:42.564Z https://longevityharbor.com/en/watch/URdsqBHT71Y Not all Senescent Cells are Equal https://i.ytimg.com/vi/URdsqBHT71Y/hqdefault.jpg The link to the preprint: https://www.biorxiv.org/content/10.1101/2025.08.27.672709v1.full.pdf Key-words: 1:2:3:4 punch, Adipose tissue, Aging, Apoptosis, Cancer, Cellular senescence, Chemotherapy, CyTOF, Dasatinib, Endothelial cells, Fibrosis, Frailty, GPNMB, HUVECs, Immune cells, Inflammation, JAK/STAT inhibitor, Lipopolysaccharide (LPS), Macrophages, Mass cytometry, Mice, mtDNA, Natural killer (NK) cells, Obesity, p16INK4a, p21CIP1, PAMPs, Physical dysfunction, Preadipocytes, Proliferative arrest, Quercetin, RNA sequencing, Ruxolitinib, SAβgal, SASP, SCAPs, SCID-beige mice, Senescent cell (SC), Senescent cell anti-apoptotic pathways, Senescence-associated secretory phenotype, Senolytics, Senolytic-resistant, Senolytic-sensitive, Senomorphics, Senosensitizers, Therapy-induced senescence (TIS), TLR3 agonist, Transplantation, Triple-negative breast cancer (TNBC), γH2AX https://www.youtube-nocookie.com/embed/URdsqBHT71Y 329 2025-09-05T17:05:47.000Z 2026-10-22T19:43:47.634Z https://longevityharbor.com/de/watch/URdsqBHT71Y Not all Senescent Cells are Equal https://i.ytimg.com/vi/URdsqBHT71Y/hqdefault.jpg The link to the preprint: https://www.biorxiv.org/content/10.1101/2025.08.27.672709v1.full.pdf Key-words: 1:2:3:4 punch, Adipose tissue, Aging, Apoptosis, Cancer, Cellular senescence, Chemotherapy, CyTOF, Dasatinib, Endothelial cells, Fibrosis, Frailty, GPNMB, HUVECs, Immune cells, Inflammation, JAK/STAT inhibitor, Lipopolysaccharide (LPS), Macrophages, Mass cytometry, Mice, mtDNA, Natural killer (NK) cells, Obesity, p16INK4a, p21CIP1, PAMPs, Physical dysfunction, Preadipocytes, Proliferative arrest, Quercetin, RNA sequencing, Ruxolitinib, SAβgal, SASP, SCAPs, SCID-beige mice, Senescent cell (SC), Senescent cell anti-apoptotic pathways, Senescence-associated secretory phenotype, Senolytics, Senolytic-resistant, Senolytic-sensitive, Senomorphics, Senosensitizers, Therapy-induced senescence (TIS), TLR3 agonist, Transplantation, Triple-negative breast cancer (TNBC), γH2AX https://www.youtube-nocookie.com/embed/URdsqBHT71Y 329 2025-09-05T17:05:47.000Z 2026-10-22T19:43:47.634Z https://longevityharbor.com/en/watch/US2aaISId1U Dentist Reveals Exciting Research Findings Involving Rapamycin on Oral Health | 5 - Jon An, DDS, PhD https://i.ytimg.com/vi/US2aaISId1U/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Matt and guest Jonathan An, Assistant Professor of Oral Health Sciences at the University of Washington School of Dentistry, discuss oral health and its relationship to aging, including published studies involving rapamycin effects on oral health. This is a 3-part episode. 0:00 Are there any longevity interventions that are demonstrably effective for improving oral health? 1:55 What is the connection between aging and oral health? 4:09 What normal aging in a mouse looks like chronologically/studying aging in animal models 11:45 How Jonathan started out approaching the topic of periodontal disease in aged mice 14:00 Jonathan's study: Rapamycin treatment attenuates age-associated periodontitis disease in mice 28:12 Jonathan's study: Rapamycin rejuvenates oral health in aging mice 46:05 Are the effects of rapamycin on oral health shown in the paper systemic or local? Would rapamycin toothpaste work? 49:23 What Jonathan has learned since the rejuvenation study 54:06 What do we know about rapamycin's effects on oral health in humans? 59:00 An upcoming clinical trial of rapamycin's effects on periodontal disease in humans Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the appl https://www.youtube-nocookie.com/embed/US2aaISId1U 4393 2024-02-19T15:00:32.000Z 2026-10-22T19:32:36.533Z https://longevityharbor.com/de/watch/US2aaISId1U Dentist Reveals Exciting Research Findings Involving Rapamycin on Oral Health | 5 - Jon An, DDS, PhD https://i.ytimg.com/vi/US2aaISId1U/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Matt and guest Jonathan An, Assistant Professor of Oral Health Sciences at the University of Washington School of Dentistry, discuss oral health and its relationship to aging, including published studies involving rapamycin effects on oral health. This is a 3-part episode. 0:00 Are there any longevity interventions that are demonstrably effective for improving oral health? 1:55 What is the connection between aging and oral health? 4:09 What normal aging in a mouse looks like chronologically/studying aging in animal models 11:45 How Jonathan started out approaching the topic of periodontal disease in aged mice 14:00 Jonathan's study: Rapamycin treatment attenuates age-associated periodontitis disease in mice 28:12 Jonathan's study: Rapamycin rejuvenates oral health in aging mice 46:05 Are the effects of rapamycin on oral health shown in the paper systemic or local? Would rapamycin toothpaste work? 49:23 What Jonathan has learned since the rejuvenation study 54:06 What do we know about rapamycin's effects on oral health in humans? 59:00 An upcoming clinical trial of rapamycin's effects on periodontal disease in humans Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the appl https://www.youtube-nocookie.com/embed/US2aaISId1U 4393 2024-02-19T15:00:32.000Z 2026-10-22T19:32:36.533Z https://longevityharbor.com/en/watch/USzSlDUyMK0 Physio Reveals: 5 Science-Backed Exercises that Reverse Aging https://i.ytimg.com/vi/USzSlDUyMK0/hqdefault.jpg 👇 FREE Exercise Guide - Build Incredible Strength 💪 https://mind-body-horizons.kit.com/313492e6f9 If you want to feel and move like you're 20 years younger, then this video is perfect for you! Physiotherapist, Shrey Vazir, will show you 5 Anti-Aging exercises that can help you stay strong and healthy as you age! 👇 Watch me next!: 🔹 The ONLY 3 Exercises You Need to Climb Stairs Easily (Ages 60+): https://www.youtube.com/watch?v=g503tzMcG74&t=0s 🔹 ONE Exercise that Instantly Improves Walking (Ages 60+): https://youtu.be/3ShaUs-wDb0?si=iz2gZFtvMcFF44fR 🔹 The Best Back Exercises for ages 55+ for Flexibility and Pain-Relief: https://www.youtube.com/watch?v=sf4FnvbrfXw ⏰ TIMESTAMPS ⏰ 0:00 - How to move and feel like you're 20 Years Younger! 0:29 - The Key Factor that Impacts Aging and Longevity 1:13 - Groundbreaking Study Reveals Anti-Aging Exercise Approach 2:08 - Best Exercise for Leg Strength 3:29 - The Golden Rule 4:55 - How to Improve your Strength, Balance & Flexibility 13:20 - Simple Trick to Improve Walking ============================================================== ⚠️ DISCLAIMER ⚠️ The content on this website and related Company properties, including exercises, videos, documents, and other materials, is provided for educational and informational purposes only and does not constitute medical advice, diagnosis, or treatment. Accessing or using this content does not create a therapist–client, doctor–patient, or healthcare provider–patient relationship. The information is based on current medical research and/or the experience of the presenter; however, medical knowledge is constantly evolving, and the content may not be fully up to date, comprehensive, or applicable to your specific condition. Always seek the advice of a qualified physician or healthcare professional with any questions regarding a medical condition and before beginning any health, wellness, or exercise program or making medical decisions. Neither the Company, its representatives, nor any presenters make any representations or https://www.youtube-nocookie.com/embed/USzSlDUyMK0 821 2024-09-13T14:00:34.000Z 2026-10-22T17:43:36.939Z https://longevityharbor.com/de/watch/USzSlDUyMK0 Physio Reveals: 5 Science-Backed Exercises that Reverse Aging https://i.ytimg.com/vi/USzSlDUyMK0/hqdefault.jpg 👇 FREE Exercise Guide - Build Incredible Strength 💪 https://mind-body-horizons.kit.com/313492e6f9 If you want to feel and move like you're 20 years younger, then this video is perfect for you! Physiotherapist, Shrey Vazir, will show you 5 Anti-Aging exercises that can help you stay strong and healthy as you age! 👇 Watch me next!: 🔹 The ONLY 3 Exercises You Need to Climb Stairs Easily (Ages 60+): https://www.youtube.com/watch?v=g503tzMcG74&t=0s 🔹 ONE Exercise that Instantly Improves Walking (Ages 60+): https://youtu.be/3ShaUs-wDb0?si=iz2gZFtvMcFF44fR 🔹 The Best Back Exercises for ages 55+ for Flexibility and Pain-Relief: https://www.youtube.com/watch?v=sf4FnvbrfXw ⏰ TIMESTAMPS ⏰ 0:00 - How to move and feel like you're 20 Years Younger! 0:29 - The Key Factor that Impacts Aging and Longevity 1:13 - Groundbreaking Study Reveals Anti-Aging Exercise Approach 2:08 - Best Exercise for Leg Strength 3:29 - The Golden Rule 4:55 - How to Improve your Strength, Balance & Flexibility 13:20 - Simple Trick to Improve Walking ============================================================== ⚠️ DISCLAIMER ⚠️ The content on this website and related Company properties, including exercises, videos, documents, and other materials, is provided for educational and informational purposes only and does not constitute medical advice, diagnosis, or treatment. Accessing or using this content does not create a therapist–client, doctor–patient, or healthcare provider–patient relationship. The information is based on current medical research and/or the experience of the presenter; however, medical knowledge is constantly evolving, and the content may not be fully up to date, comprehensive, or applicable to your specific condition. Always seek the advice of a qualified physician or healthcare professional with any questions regarding a medical condition and before beginning any health, wellness, or exercise program or making medical decisions. Neither the Company, its representatives, nor any presenters make any representations or https://www.youtube-nocookie.com/embed/USzSlDUyMK0 821 2024-09-13T14:00:34.000Z 2026-10-22T17:43:36.939Z https://longevityharbor.com/en/watch/UUxSc7QXgHE Video description links deep sleep, epigenetic clocks and a 65°F room https://i.ytimg.com/vi/UUxSc7QXgHE/hqdefault.jpg The description claims deep sleep and biological age are connected, cites a 1% deep-sleep drop as 2-3 biological years, and presents a 65°F room as an environmental fix; these are creator claims, not verified results. https://www.youtube-nocookie.com/embed/UUxSc7QXgHE 129 2026-06-08T12:00:22.000Z 2026-10-23T00:05:20.099Z https://longevityharbor.com/de/watch/UUxSc7QXgHE Videobeschreibung verknüpft Tiefschlaf, epigenetische Uhren und 65°F https://i.ytimg.com/vi/UUxSc7QXgHE/hqdefault.jpg Die Beschreibung behauptet einen Zusammenhang von Tiefschlaf und biologischem Alter, nennt 1 % weniger Tiefschlaf als 2–3 biologische Jahre und präsentiert 65°F im Raum als Umwelt-Korrektur; das sind Aussagen des Erstellers, keine geprüften Ergebnisse. https://www.youtube-nocookie.com/embed/UUxSc7QXgHE 129 2026-06-08T12:00:22.000Z 2026-10-23T00:05:20.099Z https://longevityharbor.com/en/watch/UVGBfrfPq98 324‒Metabolism, energy balance, and aging: the impact of diet, calorie restriction & macronutrients https://i.ytimg.com/vi/UVGBfrfPq98/hqdefault.jpg View show notes here: https://bit.ly/3YrLl41 Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Eric Ravussin is a world-renowned expert on obesity, metabolism, and aging whose pioneering research has shaped much of what we understand today about energy balance and caloric restriction. In this episode, Eric shares insights from his cutting-edge work on energy expenditure—a critical factor in understanding how our bodies regulate weight and appetite. He discusses methods for measuring energy output, energy balance, food intake, and appetite regulation, and explores key studies on macronutrient manipulation. Eric then delves into the CALERIE study on caloric restriction, highlighting insights related to biomarkers of both primary and secondary aging. The conversation also covers the potential of GLP-1 agonists to replicate these effects and looks ahead to how AI and technology could transform metabolic research in the coming years. We discuss: 0:00:00 - Intro 0:01:34 - Eric’s background and current work metabolism and measuring energy expenditure 0:07:18 - The science behind metabolic chambers for measuring energy expenditure, and the complexities of indirect and direct calorimetry 0:17:47 - The body's regulatory systems for maintaining energy balance and the primary influence of energy intake on body weight 0:25:00 - The epidemic of obesity and a discussion of resting metabolic rate 0:29:15 -The impact of exercise, appetite, gut hormones, and eating patterns on weight regulation 0:40:11 - Experiments looking at how macronutrient composition affects energy expenditure 0:54:05 - The challenges of studying diet in real-life settings, the potential of personalized nutrition, and how public health policy could play a role in guiding nutritional habits 1:13:27 - The importance of protein in the diet, the limitations of dietary data collection, and how AI could potentially transform nutrition science 1:21:30 https://www.youtube-nocookie.com/embed/UVGBfrfPq98 8332 2024-11-04T08:30:09.000Z 2026-10-22T18:43:11.744Z https://longevityharbor.com/de/watch/UVGBfrfPq98 324‒Metabolism, energy balance, and aging: the impact of diet, calorie restriction & macronutrients https://i.ytimg.com/vi/UVGBfrfPq98/hqdefault.jpg View show notes here: https://bit.ly/3YrLl41 Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Eric Ravussin is a world-renowned expert on obesity, metabolism, and aging whose pioneering research has shaped much of what we understand today about energy balance and caloric restriction. In this episode, Eric shares insights from his cutting-edge work on energy expenditure—a critical factor in understanding how our bodies regulate weight and appetite. He discusses methods for measuring energy output, energy balance, food intake, and appetite regulation, and explores key studies on macronutrient manipulation. Eric then delves into the CALERIE study on caloric restriction, highlighting insights related to biomarkers of both primary and secondary aging. The conversation also covers the potential of GLP-1 agonists to replicate these effects and looks ahead to how AI and technology could transform metabolic research in the coming years. We discuss: 0:00:00 - Intro 0:01:34 - Eric’s background and current work metabolism and measuring energy expenditure 0:07:18 - The science behind metabolic chambers for measuring energy expenditure, and the complexities of indirect and direct calorimetry 0:17:47 - The body's regulatory systems for maintaining energy balance and the primary influence of energy intake on body weight 0:25:00 - The epidemic of obesity and a discussion of resting metabolic rate 0:29:15 -The impact of exercise, appetite, gut hormones, and eating patterns on weight regulation 0:40:11 - Experiments looking at how macronutrient composition affects energy expenditure 0:54:05 - The challenges of studying diet in real-life settings, the potential of personalized nutrition, and how public health policy could play a role in guiding nutritional habits 1:13:27 - The importance of protein in the diet, the limitations of dietary data collection, and how AI could potentially transform nutrition science 1:21:30 https://www.youtube-nocookie.com/embed/UVGBfrfPq98 8332 2024-11-04T08:30:09.000Z 2026-10-22T18:43:11.744Z https://longevityharbor.com/en/watch/UZ7JpNfjAJ4 Welche Ernährung lässt Dich lange und gesund leben? https://i.ytimg.com/vi/UZ7JpNfjAJ4/hqdefault.jpg Um die Frage nach der richtigen Ernährung für gesunde Langlebigkeit zu beantworten, lohnt sich ein Blick in die fünf Blue Zones - Regionen, in denen die Menschen länger leben als der Durchschnitt. Zu diesen zählen (von Ost nach West) Okinawa in Japan, Icaria (Griechenland), Sardinien (Italien), Nicoya (Costa Rica) und Loma Linda (USA). Allen gemeinsam ist eine pflanzenbasierte Kost, jedoch variieren die anderen Gewohnheiten zum Teil erheblich. Auch die moderne Wissenschaft ist sich uneinig und die Studienlage teils widersprüchlich. Die Well Aging Ernährung bei EURASIAMED verbindet das Wissen der traditierten Gesundheitslehren aus Asien (China, Japan und Indien) mit neuesten Erkenntnissen aus der Alternsforschung zu einer flexiblen Einheit. Dieses Video ist ein Ausschnitt aus Lektion 2 unserer Ausbildung zum Well Aging Consultant: 👉 Informationen unter https://wellaging.institute/event/well-aging-consultant/ _________________ IN DIESEM VIDEO 00:00 Einführung: Welche Empfehlungen sind richtig? 04:38 Drei wichtige Perspektiven im Well Aging 08:54 Die wichtigsten Einflüsse einer Well Aging Ernährung 13:19 Zehn Grundregeln einer Well Aging Ernährung 21:58 Fazit _________________ Weitere Videoempfehlungen zum Thema: 👉 Well-Aging #1 - Altern holistisch verstehen | https://youtu.be/7RaPJeWzdy4 👉 Dinner Cancelling: Schneller abnehmen. Langsamer altern | https://youtu.be/igC4Cqx3uFE 👉 Alkoholfrei(er) länger und gesünder leben: So gelingt es | https://youtu.be/cjd9kZYv5BQ _________________ Suchst Du nach einer professionellen Well Aging Diagnostik und Medizin? Dann melde Dich gerne in unserer Privatpraxis: 👉 https://www.eurasiamed.de/privatpraxis/well-aging-medizin/ _________________ Interessierst Du Dich für ganzheitliches Well Aging und Healthy Longevity? Dann informiere Dich in unserem Well Aging Institute bei EURASIAMED: 👉 https://wellaging.institute/ _________________ Abonniere unseren Kanal für deine wöchentliche Portion Wissen zu Themen rund um eine ganzheitliche Gesundheit und - ganz wichtig - ak https://www.youtube-nocookie.com/embed/UZ7JpNfjAJ4 1386 2024-11-24T08:00:20.000Z 2026-10-22T18:43:10.837Z https://longevityharbor.com/de/watch/UZ7JpNfjAJ4 Welche Ernährung lässt Dich lange und gesund leben? https://i.ytimg.com/vi/UZ7JpNfjAJ4/hqdefault.jpg Um die Frage nach der richtigen Ernährung für gesunde Langlebigkeit zu beantworten, lohnt sich ein Blick in die fünf Blue Zones - Regionen, in denen die Menschen länger leben als der Durchschnitt. Zu diesen zählen (von Ost nach West) Okinawa in Japan, Icaria (Griechenland), Sardinien (Italien), Nicoya (Costa Rica) und Loma Linda (USA). Allen gemeinsam ist eine pflanzenbasierte Kost, jedoch variieren die anderen Gewohnheiten zum Teil erheblich. Auch die moderne Wissenschaft ist sich uneinig und die Studienlage teils widersprüchlich. Die Well Aging Ernährung bei EURASIAMED verbindet das Wissen der traditierten Gesundheitslehren aus Asien (China, Japan und Indien) mit neuesten Erkenntnissen aus der Alternsforschung zu einer flexiblen Einheit. Dieses Video ist ein Ausschnitt aus Lektion 2 unserer Ausbildung zum Well Aging Consultant: 👉 Informationen unter https://wellaging.institute/event/well-aging-consultant/ _________________ IN DIESEM VIDEO 00:00 Einführung: Welche Empfehlungen sind richtig? 04:38 Drei wichtige Perspektiven im Well Aging 08:54 Die wichtigsten Einflüsse einer Well Aging Ernährung 13:19 Zehn Grundregeln einer Well Aging Ernährung 21:58 Fazit _________________ Weitere Videoempfehlungen zum Thema: 👉 Well-Aging #1 - Altern holistisch verstehen | https://youtu.be/7RaPJeWzdy4 👉 Dinner Cancelling: Schneller abnehmen. Langsamer altern | https://youtu.be/igC4Cqx3uFE 👉 Alkoholfrei(er) länger und gesünder leben: So gelingt es | https://youtu.be/cjd9kZYv5BQ _________________ Suchst Du nach einer professionellen Well Aging Diagnostik und Medizin? Dann melde Dich gerne in unserer Privatpraxis: 👉 https://www.eurasiamed.de/privatpraxis/well-aging-medizin/ _________________ Interessierst Du Dich für ganzheitliches Well Aging und Healthy Longevity? Dann informiere Dich in unserem Well Aging Institute bei EURASIAMED: 👉 https://wellaging.institute/ _________________ Abonniere unseren Kanal für deine wöchentliche Portion Wissen zu Themen rund um eine ganzheitliche Gesundheit und - ganz wichtig - ak https://www.youtube-nocookie.com/embed/UZ7JpNfjAJ4 1386 2024-11-24T08:00:20.000Z 2026-10-22T18:43:10.837Z https://longevityharbor.com/en/watch/U_lZy1amf5o Hallmarks of Aging - Damage and Repair https://i.ytimg.com/vi/U_lZy1amf5o/hqdefault.jpg Prof. Lene Juel Rasmussen - Managing Director, Center for Healthy Aging, Department of Cellular and Molecular Medicine, Copenhagen University, Denmark Life in Extreme Conditions: A Lesson from Nature Dead Sea Research Institute Tel Aviv University 8.1.18 https://www.youtube-nocookie.com/embed/U_lZy1amf5o 603 2018-01-18T12:19:23.000Z 2026-10-22T17:43:40.157Z https://longevityharbor.com/de/watch/U_lZy1amf5o Hallmarks of Aging - Damage and Repair https://i.ytimg.com/vi/U_lZy1amf5o/hqdefault.jpg Prof. Lene Juel Rasmussen - Managing Director, Center for Healthy Aging, Department of Cellular and Molecular Medicine, Copenhagen University, Denmark Life in Extreme Conditions: A Lesson from Nature Dead Sea Research Institute Tel Aviv University 8.1.18 https://www.youtube-nocookie.com/embed/U_lZy1amf5o 603 2018-01-18T12:19:23.000Z 2026-10-22T17:43:40.157Z https://longevityharbor.com/en/watch/U_tsoNTu_Gg The Truth Behind NMN | MOONSHOTS https://i.ytimg.com/vi/U_tsoNTu_Gg/hqdefault.jpg In my conversation with David Sinclair we dive into the truth behind nmn: the right dosage, best ingestion forms, where to get it, and more...  I know this is a debated topic, let's bring some light to it. Full episode of Moonshots Podcast on Youtube/Spotify/Apple - search "Harvard Prof Reveals Age-Reversing Science to Look & Feel Younger" https://www.youtube-nocookie.com/embed/U_tsoNTu_Gg 129 2025-07-02T17:04:19.000Z 2026-10-22T20:11:47.097Z https://longevityharbor.com/de/watch/U_tsoNTu_Gg The Truth Behind NMN | MOONSHOTS https://i.ytimg.com/vi/U_tsoNTu_Gg/hqdefault.jpg In my conversation with David Sinclair we dive into the truth behind nmn: the right dosage, best ingestion forms, where to get it, and more...  I know this is a debated topic, let's bring some light to it. Full episode of Moonshots Podcast on Youtube/Spotify/Apple - search "Harvard Prof Reveals Age-Reversing Science to Look & Feel Younger" https://www.youtube-nocookie.com/embed/U_tsoNTu_Gg 129 2025-07-02T17:04:19.000Z 2026-10-22T20:11:47.097Z https://longevityharbor.com/en/watch/Ubz-Mi5ff3I A second Aging, Geroscience and Longevity Symposium – Session two https://i.ytimg.com/vi/Ubz-Mi5ff3I/hqdefault.jpg eLife Reviewing Editors, Sara Hägg and Dario Riccardo Valenzano, chaired this online symposium where authors whose papers have been published in our recent Aging, Geroscience and Longevity Special Issue presented their key findings. These accepted authors presented their research through live and pre-recorded presentations. Session two includes the following speakers: 00:00:04 Michael Stout – Oklahoma University Health Sciences Center (OUHSC), United States 00:20:49 Yang Lyu – Department of Molecular and Integrative Physiology and Geriatrics Center, University of Michigan, United States 00:36:43 Huiliang Zhang – Department of Laboratory Medicine and Pathology, University of Washington, United States 00:54:49 Karen Krukowski – University of California San Francisco, United States 01:20:30 Ghada Alsaleh – The Kennedy Institute of Rheumatology, NDORMS, University of Oxford, United Kingdom https://www.youtube-nocookie.com/embed/Ubz-Mi5ff3I 6090 2021-03-16T12:43:45.000Z 2026-10-22T17:43:40.131Z https://longevityharbor.com/de/watch/Ubz-Mi5ff3I A second Aging, Geroscience and Longevity Symposium – Session two https://i.ytimg.com/vi/Ubz-Mi5ff3I/hqdefault.jpg eLife Reviewing Editors, Sara Hägg and Dario Riccardo Valenzano, chaired this online symposium where authors whose papers have been published in our recent Aging, Geroscience and Longevity Special Issue presented their key findings. These accepted authors presented their research through live and pre-recorded presentations. Session two includes the following speakers: 00:00:04 Michael Stout – Oklahoma University Health Sciences Center (OUHSC), United States 00:20:49 Yang Lyu – Department of Molecular and Integrative Physiology and Geriatrics Center, University of Michigan, United States 00:36:43 Huiliang Zhang – Department of Laboratory Medicine and Pathology, University of Washington, United States 00:54:49 Karen Krukowski – University of California San Francisco, United States 01:20:30 Ghada Alsaleh – The Kennedy Institute of Rheumatology, NDORMS, University of Oxford, United Kingdom https://www.youtube-nocookie.com/embed/Ubz-Mi5ff3I 6090 2021-03-16T12:43:45.000Z 2026-10-22T17:43:40.131Z https://longevityharbor.com/en/watch/UcBAbcqo0CM Die 4 UNVERZICHTBAREN und GÜNSTIGEN FRÜCHTE für Senioren, die lange leben wollen! https://i.ytimg.com/vi/UcBAbcqo0CM/hqdefault.jpg Die 4 UNVERZICHTBAREN und GÜNSTIGEN FRÜCHTE für Senioren, die lange leben wollen! Entdecken Sie wissenschaftlich belegte Früchte, die Senioren dabei helfen, würdevoll zu altern und Vitalität zu bewahren. Lernen Sie 4 evidenzbasierte Nährstoffkraftpakete kennen, die kognitive Funktion, Herzgesundheit und allgemeines Wohlbefinden für Erwachsene über 60 Jahre unterstützen. In diesem umfassenden Leitfaden erkunden wir, wie Blaubeeren, Brombeeren, Himbeeren und Avocados essentielle Nährstoffe für gesundes Altern liefern. Forschungen der Harvard Medical School und des Journal of Nutrition zeigen, wie diese Lebensmittel Gedächtnis unterstützen, Entzündungen reduzieren und Herz-Kreislauf-Gesundheit fördern können. 🌿 Was Sie Lernen: • Wie Antioxidantien vor altersbedingtem Abbau schützen • Optimale Portionsgrößen und Timing für maximale Vorteile • Evidenzbasierte Ernährungsstrategien für Senioren • 30-Tage-Umsetzungsplan für nachhaltige Gesundheit Keywords: Seniorenernährung, Anti-Aging Lebensmittel, gesundes Altern, Seniorengesundheit, Ernährung für Senioren, kognitive Gesundheit, herzgesunde Lebensmittel, antioxidative Lebensmittel, Seniorenwohl, altersbedingte Ernährung Hashtags: #Seniorenernährung #GesundesAltern #AntiAgingLebensmittel #Seniorengesundheit #ErnährungFürSenioren #KognitiveGesundheit #Herzgesund #Seniorenwohl #GesundeErnährung #Ernährungswissenschaft #Seniorenpflege #WohlbefindenReise #GesunderLebensstil #SeniorenFitness #WürdevollAltern https://www.youtube-nocookie.com/embed/UcBAbcqo0CM 1475 2025-06-19T21:00:36.000Z 2026-10-22T20:11:49.468Z https://longevityharbor.com/de/watch/UcBAbcqo0CM Die 4 UNVERZICHTBAREN und GÜNSTIGEN FRÜCHTE für Senioren, die lange leben wollen! https://i.ytimg.com/vi/UcBAbcqo0CM/hqdefault.jpg Die 4 UNVERZICHTBAREN und GÜNSTIGEN FRÜCHTE für Senioren, die lange leben wollen! Entdecken Sie wissenschaftlich belegte Früchte, die Senioren dabei helfen, würdevoll zu altern und Vitalität zu bewahren. Lernen Sie 4 evidenzbasierte Nährstoffkraftpakete kennen, die kognitive Funktion, Herzgesundheit und allgemeines Wohlbefinden für Erwachsene über 60 Jahre unterstützen. In diesem umfassenden Leitfaden erkunden wir, wie Blaubeeren, Brombeeren, Himbeeren und Avocados essentielle Nährstoffe für gesundes Altern liefern. Forschungen der Harvard Medical School und des Journal of Nutrition zeigen, wie diese Lebensmittel Gedächtnis unterstützen, Entzündungen reduzieren und Herz-Kreislauf-Gesundheit fördern können. 🌿 Was Sie Lernen: • Wie Antioxidantien vor altersbedingtem Abbau schützen • Optimale Portionsgrößen und Timing für maximale Vorteile • Evidenzbasierte Ernährungsstrategien für Senioren • 30-Tage-Umsetzungsplan für nachhaltige Gesundheit Keywords: Seniorenernährung, Anti-Aging Lebensmittel, gesundes Altern, Seniorengesundheit, Ernährung für Senioren, kognitive Gesundheit, herzgesunde Lebensmittel, antioxidative Lebensmittel, Seniorenwohl, altersbedingte Ernährung Hashtags: #Seniorenernährung #GesundesAltern #AntiAgingLebensmittel #Seniorengesundheit #ErnährungFürSenioren #KognitiveGesundheit #Herzgesund #Seniorenwohl #GesundeErnährung #Ernährungswissenschaft #Seniorenpflege #WohlbefindenReise #GesunderLebensstil #SeniorenFitness #WürdevollAltern https://www.youtube-nocookie.com/embed/UcBAbcqo0CM 1475 2025-06-19T21:00:36.000Z 2026-10-22T20:11:49.468Z https://longevityharbor.com/en/watch/UeesmVbOGPY CAR T Cells: The Ultimate Anti-Aging Solution? | 16 - Longevity This Week #2 https://i.ytimg.com/vi/UeesmVbOGPY/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan While scientific papers are generally considered trustworthy sources of information, it's important to approach them with a critical mindset and to avoid blindly accepting their claims. The peer-review process, which helps ensure high research quality, is not foolproof. Errors or biases can slip through the cracks. In reading a paper, we should independently evaluate the evidence, scrutinize the methodology, and reflect on alternative interpretations of the data. Considering the influence of funding sources, conflicts of interest, and the potential for selective reporting can also help in maintaining a healthy skepticism about new information. In this episode of Longevity This Week, Matt takes us through a recently-published paper about the effects of senolytic CAR T cell therapy on the aging process in mice to help us figure out whether the paper's claims hold water. He also analyzes a BBC article describing the findings. Popular press adaptations of the scientific literature often serve as a useful bridge between the complex world of research and the general public, but can be misleading in their attempts to make science accessible. They might, for example, inadvertently distort or oversimplify findings, exaggerate the significance of results, or selectively report research while ignoring contradictory or inconclusive evidence from other sources. We hope this episode will encourage viewers to approach science communication with a discerning eye, and to stay vigilant, curious, and open-minded in learning about the latest discoveries and developments. 0:00 Trailer 0:39 Introduction 2:11 Paper: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction 4:30 The paper's title 5:44 Going through the abstract 17:37 Does this intervention really improve health and delay aging? 18:32 Metabolic improvements 25:06 Exercise capacity 29:52 Other effects on aging 33:24 Possible takeaways from the paper 34:08 BBC art https://www.youtube-nocookie.com/embed/UeesmVbOGPY 3034 2024-03-18T14:00:21.000Z 2026-10-22T18:32:11.610Z https://longevityharbor.com/de/watch/UeesmVbOGPY CAR T Cells: The Ultimate Anti-Aging Solution? | 16 - Longevity This Week #2 https://i.ytimg.com/vi/UeesmVbOGPY/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan While scientific papers are generally considered trustworthy sources of information, it's important to approach them with a critical mindset and to avoid blindly accepting their claims. The peer-review process, which helps ensure high research quality, is not foolproof. Errors or biases can slip through the cracks. In reading a paper, we should independently evaluate the evidence, scrutinize the methodology, and reflect on alternative interpretations of the data. Considering the influence of funding sources, conflicts of interest, and the potential for selective reporting can also help in maintaining a healthy skepticism about new information. In this episode of Longevity This Week, Matt takes us through a recently-published paper about the effects of senolytic CAR T cell therapy on the aging process in mice to help us figure out whether the paper's claims hold water. He also analyzes a BBC article describing the findings. Popular press adaptations of the scientific literature often serve as a useful bridge between the complex world of research and the general public, but can be misleading in their attempts to make science accessible. They might, for example, inadvertently distort or oversimplify findings, exaggerate the significance of results, or selectively report research while ignoring contradictory or inconclusive evidence from other sources. We hope this episode will encourage viewers to approach science communication with a discerning eye, and to stay vigilant, curious, and open-minded in learning about the latest discoveries and developments. 0:00 Trailer 0:39 Introduction 2:11 Paper: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction 4:30 The paper's title 5:44 Going through the abstract 17:37 Does this intervention really improve health and delay aging? 18:32 Metabolic improvements 25:06 Exercise capacity 29:52 Other effects on aging 33:24 Possible takeaways from the paper 34:08 BBC art https://www.youtube-nocookie.com/embed/UeesmVbOGPY 3034 2024-03-18T14:00:21.000Z 2026-10-22T18:32:11.610Z https://longevityharbor.com/en/watch/UgpiehBYJyU 5 Longevity Breakthroughs This Week (Zombie Cells, NAD+, 9 Extra Years) https://i.ytimg.com/vi/UgpiehBYJyU/hqdefault.jpg This week in longevity science: the first senolytic drug clears Phase 1, a major study finds your genes matter far less than we thought, three daily habits linked to 9+ extra years of life, an $80M epigenetic reprogramming trial moves forward, and the biggest NAD+ consensus review in years delivers a complicated verdict. Which of these five would you actually act on? Drop it in the comments. Follow for weekly longevity updates every week. https://www.youtube-nocookie.com/embed/UgpiehBYJyU 162 2026-04-18T19:10:50.000Z 2026-10-22T19:21:21.853Z https://longevityharbor.com/de/watch/UgpiehBYJyU 5 Longevity Breakthroughs This Week (Zombie Cells, NAD+, 9 Extra Years) https://i.ytimg.com/vi/UgpiehBYJyU/hqdefault.jpg This week in longevity science: the first senolytic drug clears Phase 1, a major study finds your genes matter far less than we thought, three daily habits linked to 9+ extra years of life, an $80M epigenetic reprogramming trial moves forward, and the biggest NAD+ consensus review in years delivers a complicated verdict. Which of these five would you actually act on? Drop it in the comments. Follow for weekly longevity updates every week. https://www.youtube-nocookie.com/embed/UgpiehBYJyU 162 2026-04-18T19:10:50.000Z 2026-10-22T19:21:21.853Z https://longevityharbor.com/en/watch/UoQljvHBxw8 Video description: epigenetic clocks and biological age explained https://i.ytimg.com/vi/UoQljvHBxw8/hqdefault.jpg The description presents a plain-language series episode on longevity that covers epigenetics, how an epigenetic clock reads age, the main clocks and honest caveats. It states the content is educational only and not medical advice. https://www.youtube-nocookie.com/embed/UoQljvHBxw8 237 2026-07-20T03:46:52.000Z 2026-10-22T23:28:08.934Z https://longevityharbor.com/de/watch/UoQljvHBxw8 Videobeschreibung: epigenetische Uhren und biologisches Alter erklärt https://i.ytimg.com/vi/UoQljvHBxw8/hqdefault.jpg Die Beschreibung stellt eine Episode einer allgemein verständlichen Longevity-Reihe vor: Es geht um Epigenetik, darum, wie eine epigenetische Uhr das Alter abliest, um die wichtigsten Uhren und um ehrliche Einschränkungen. Der Inhalt sei nur Bildung und keine medizinische Beratung. https://www.youtube-nocookie.com/embed/UoQljvHBxw8 237 2026-07-20T03:46:52.000Z 2026-10-22T23:28:08.934Z https://longevityharbor.com/en/watch/UqBVkckXMek Aging clocks - how to measure biological age. https://i.ytimg.com/vi/UqBVkckXMek/hqdefault.jpg SPONSOR - Longevity.Technology - https://www.longevity.technology/?utm_source=YouTube&utm_medium=social&utm_campaign=SSSagingclocks I hope you have some time on you hands as today we will talk all about aging clocks... When we think of age we typically think of our chronological age - how many years have passed since we were born. Whilst a useful measurement to assess risk for different diseases, it now seems there are even better ways of predicting your health status. This can be done by inferring biological age, an age that can be derived from different biomarkers and the use of aging clocks. This field of aging clocks is growing rapidly and there is now evidence to support the use of many different types of aging clocks; epigenetic/DNA methylation, transcriptomic, human microbiome and proteomic to name a few. But do they fulfil the key desirable features of aging clocks and what can we learn from them about the aging process? Well in this video we will address these areas and also see what aging clocks are currently commercially available as well as the future challenges the field faces. TIMESTAMPS Intro - 00:00 Aging clocks & Biological age - 00:30 Features of aging clocks - 02:30 Why aging clocks are useful - 04:45 Epigenetic & DNA methylation - 05:25 Biological age reversal - 07:40 Other clocks - 08:10 Proteomic clocks & iAge - 08:45 Challenges - 10:10 Commercially available - 12:30 REFERENCES Lehallier, B., Gate, D., Schaum, N. et al. Undulating changes in human plasma proteome profiles across the lifespan. Nat Med 25, 1843–1850 (2019). https://doi.org/10.1038/s41591-019-0673-2 Horvath, S. DNA methylation age of human tissues and cell types. Genome Biol 14, 3156 (2013). https://doi.org/10.1186/gb-2013-14-10-r115 Lu, Y., Brommer, B., Tian, X. et al. Reprogramming to recover youthful epigenetic information and restore vision. Nature 588, 124–129 (2020). https://doi.org/10.1038/s41586-020-2975-4 Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whit https://www.youtube-nocookie.com/embed/UqBVkckXMek 801 2021-07-30T14:00:16.000Z 2026-10-22T17:43:35.239Z https://longevityharbor.com/de/watch/UqBVkckXMek Aging clocks - how to measure biological age. https://i.ytimg.com/vi/UqBVkckXMek/hqdefault.jpg SPONSOR - Longevity.Technology - https://www.longevity.technology/?utm_source=YouTube&utm_medium=social&utm_campaign=SSSagingclocks I hope you have some time on you hands as today we will talk all about aging clocks... When we think of age we typically think of our chronological age - how many years have passed since we were born. Whilst a useful measurement to assess risk for different diseases, it now seems there are even better ways of predicting your health status. This can be done by inferring biological age, an age that can be derived from different biomarkers and the use of aging clocks. This field of aging clocks is growing rapidly and there is now evidence to support the use of many different types of aging clocks; epigenetic/DNA methylation, transcriptomic, human microbiome and proteomic to name a few. But do they fulfil the key desirable features of aging clocks and what can we learn from them about the aging process? Well in this video we will address these areas and also see what aging clocks are currently commercially available as well as the future challenges the field faces. TIMESTAMPS Intro - 00:00 Aging clocks & Biological age - 00:30 Features of aging clocks - 02:30 Why aging clocks are useful - 04:45 Epigenetic & DNA methylation - 05:25 Biological age reversal - 07:40 Other clocks - 08:10 Proteomic clocks & iAge - 08:45 Challenges - 10:10 Commercially available - 12:30 REFERENCES Lehallier, B., Gate, D., Schaum, N. et al. Undulating changes in human plasma proteome profiles across the lifespan. Nat Med 25, 1843–1850 (2019). https://doi.org/10.1038/s41591-019-0673-2 Horvath, S. DNA methylation age of human tissues and cell types. Genome Biol 14, 3156 (2013). https://doi.org/10.1186/gb-2013-14-10-r115 Lu, Y., Brommer, B., Tian, X. et al. Reprogramming to recover youthful epigenetic information and restore vision. Nature 588, 124–129 (2020). https://doi.org/10.1038/s41586-020-2975-4 Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whit https://www.youtube-nocookie.com/embed/UqBVkckXMek 801 2021-07-30T14:00:16.000Z 2026-10-22T17:43:35.239Z https://longevityharbor.com/en/watch/Ur3swWLbiiQ S1E01 - What is Aging? https://i.ytimg.com/vi/Ur3swWLbiiQ/hqdefault.jpg Season 1: The Science of Aging | Episode 1: What is Aging? In this debut episode of The Deep Dive, we set our sights on the fascinating frontier of aging biology, a field that is rapidly evolving from theoretical musings into testable science. Hosts delve into what exactly aging is and how it's measured, going beyond the simple ticking of the clock to explore the biological processes such as genomic instability and mitochondrial dysfunction. Join us as we unravel the intriguing variability in aging—from the vibrant 80-year-old ultramarathoner to the struggling 55-year-old with chronic illnesses—and ask critical questions about the disparities in healthspan versus lifespan. With a global demographic shift on the horizon, we explore the potential of geroscience to close the 'healthspan gap' and its groundbreaking implications for extending quality life years. Key topics for discussion include the promising yet complex landscape of potential interventions—from lifestyle and pharmaceuticals to cutting-edge therapies involving stem cells and gene editing. The episode emphasizes the importance of rigorous evidence in translating these scientific discoveries into practical, safe therapies that not only add years to life but life to years. https://www.youtube-nocookie.com/embed/Ur3swWLbiiQ 6189 2025-08-13T19:14:00.000Z 2026-10-22T19:32:34.464Z https://longevityharbor.com/de/watch/Ur3swWLbiiQ S1E01 - What is Aging? https://i.ytimg.com/vi/Ur3swWLbiiQ/hqdefault.jpg Season 1: The Science of Aging | Episode 1: What is Aging? In this debut episode of The Deep Dive, we set our sights on the fascinating frontier of aging biology, a field that is rapidly evolving from theoretical musings into testable science. Hosts delve into what exactly aging is and how it's measured, going beyond the simple ticking of the clock to explore the biological processes such as genomic instability and mitochondrial dysfunction. Join us as we unravel the intriguing variability in aging—from the vibrant 80-year-old ultramarathoner to the struggling 55-year-old with chronic illnesses—and ask critical questions about the disparities in healthspan versus lifespan. With a global demographic shift on the horizon, we explore the potential of geroscience to close the 'healthspan gap' and its groundbreaking implications for extending quality life years. Key topics for discussion include the promising yet complex landscape of potential interventions—from lifestyle and pharmaceuticals to cutting-edge therapies involving stem cells and gene editing. The episode emphasizes the importance of rigorous evidence in translating these scientific discoveries into practical, safe therapies that not only add years to life but life to years. https://www.youtube-nocookie.com/embed/Ur3swWLbiiQ 6189 2025-08-13T19:14:00.000Z 2026-10-22T19:32:34.464Z https://longevityharbor.com/en/watch/Us01oTGlKhA 5 wissenschaftlich fundierte Übungen für gesundes Altern ab 50 https://i.ytimg.com/vi/Us01oTGlKhA/hqdefault.jpg #ReverseAging #FitnessfürÜber50jährige #Anfängertraining Entdecken Sie 5 wissenschaftlich fundierte Übungen, die nachweislich die wichtigsten Zeichen des Alterns nach dem 50. Lebensjahr verlangsamen und sogar umkehren. Dieses für Anfänger geeignete Training wurde entwickelt, um Kraft, Gleichgewicht, Beweglichkeit und Energie zu steigern, ohne Ihre Gelenke zu belasten. Diese einfachen Bewegungen, die durch Forschungen führender Gesundheitseinrichtungen gestützt werden, tragen zur Verbesserung des Muskeltonus, zur Unterstützung der Knochendichte und zur Verlängerung der Lebenserwartung bei. Egal, ob Sie wieder mit dem Training beginnen oder ganz neu anfangen, diese Routine wird Ihnen helfen, sich jeden Tag stärker, jünger und selbstbewusster zu fühlen. Sie benötigen keine Geräte – nur Ihren Körper, ein wenig Platz und die Entschlossenheit, besser und nicht langsamer zu altern. #ReverseAging #Fitnessfürüber50-Jährige #WorkoutfürAnfänger #GesundesAltern #Langlebigkeit #Wissenschaftlichbelegt #FitnessfürSenioren #Anti-Aging-Workout #Starknach50 🔔 Haftungsausschluss: Muscle Matrix bietet keine medizinische Beratung an, und die in unseren Videos bereitgestellten Informationen, einschließlich, aber nicht beschränkt auf Texte, Grafiken, Bilder und andere Materialien, dienen ausschließlich zu Informationszwecken. Der Inhalt der Muscle Matrix-Videos ersetzt nicht die professionelle medizinische Beratung, die Sie von Ihrem Arzt einholen sollten. Alle in diesen Videos präsentierten Informationen dienen ausschließlich zu Bildungszwecken. 🔔 Haftungsausschluss zum Urheberrecht Gemäß Abschnitt 107 des Urheberrechtsgesetzes von 1976 ist eine „faire Nutzung” für Zwecke wie Kritik, Kommentare, Nachrichtenberichterstattung, Lehre, Wissenschaft und Forschung zulässig. Faire Nutzung ist eine durch das Urheberrechtsgesetz erlaubte Nutzung, die andernfalls eine Urheberrechtsverletzung darstellen könnte. Die nichtkommerzielle, pädagogische oder persönliche Nutzung spricht für eine faire Nutzung. Es besteht keine Absicht, das Urheber https://www.youtube-nocookie.com/embed/Us01oTGlKhA 1148 2025-11-04T14:22:31.000Z 2026-10-22T18:32:13.297Z https://longevityharbor.com/de/watch/Us01oTGlKhA 5 wissenschaftlich fundierte Übungen für gesundes Altern ab 50 https://i.ytimg.com/vi/Us01oTGlKhA/hqdefault.jpg #ReverseAging #FitnessfürÜber50jährige #Anfängertraining Entdecken Sie 5 wissenschaftlich fundierte Übungen, die nachweislich die wichtigsten Zeichen des Alterns nach dem 50. Lebensjahr verlangsamen und sogar umkehren. Dieses für Anfänger geeignete Training wurde entwickelt, um Kraft, Gleichgewicht, Beweglichkeit und Energie zu steigern, ohne Ihre Gelenke zu belasten. Diese einfachen Bewegungen, die durch Forschungen führender Gesundheitseinrichtungen gestützt werden, tragen zur Verbesserung des Muskeltonus, zur Unterstützung der Knochendichte und zur Verlängerung der Lebenserwartung bei. Egal, ob Sie wieder mit dem Training beginnen oder ganz neu anfangen, diese Routine wird Ihnen helfen, sich jeden Tag stärker, jünger und selbstbewusster zu fühlen. Sie benötigen keine Geräte – nur Ihren Körper, ein wenig Platz und die Entschlossenheit, besser und nicht langsamer zu altern. #ReverseAging #Fitnessfürüber50-Jährige #WorkoutfürAnfänger #GesundesAltern #Langlebigkeit #Wissenschaftlichbelegt #FitnessfürSenioren #Anti-Aging-Workout #Starknach50 🔔 Haftungsausschluss: Muscle Matrix bietet keine medizinische Beratung an, und die in unseren Videos bereitgestellten Informationen, einschließlich, aber nicht beschränkt auf Texte, Grafiken, Bilder und andere Materialien, dienen ausschließlich zu Informationszwecken. Der Inhalt der Muscle Matrix-Videos ersetzt nicht die professionelle medizinische Beratung, die Sie von Ihrem Arzt einholen sollten. Alle in diesen Videos präsentierten Informationen dienen ausschließlich zu Bildungszwecken. 🔔 Haftungsausschluss zum Urheberrecht Gemäß Abschnitt 107 des Urheberrechtsgesetzes von 1976 ist eine „faire Nutzung” für Zwecke wie Kritik, Kommentare, Nachrichtenberichterstattung, Lehre, Wissenschaft und Forschung zulässig. Faire Nutzung ist eine durch das Urheberrechtsgesetz erlaubte Nutzung, die andernfalls eine Urheberrechtsverletzung darstellen könnte. Die nichtkommerzielle, pädagogische oder persönliche Nutzung spricht für eine faire Nutzung. Es besteht keine Absicht, das Urheber https://www.youtube-nocookie.com/embed/Us01oTGlKhA 1148 2025-11-04T14:22:31.000Z 2026-10-22T18:32:13.297Z https://longevityharbor.com/en/watch/UuXqbIdkXas Promising Wonder Pill Adds Years To Dog's Life https://i.ytimg.com/vi/UuXqbIdkXas/hqdefault.jpg New research on a drug called Rapamycin is offering the exciting possibility of adding years to a dog's life. https://www.youtube-nocookie.com/embed/UuXqbIdkXas 160 2017-01-21T04:42:08.000Z 2026-10-22T17:43:41.794Z https://longevityharbor.com/de/watch/UuXqbIdkXas Promising Wonder Pill Adds Years To Dog's Life https://i.ytimg.com/vi/UuXqbIdkXas/hqdefault.jpg New research on a drug called Rapamycin is offering the exciting possibility of adding years to a dog's life. https://www.youtube-nocookie.com/embed/UuXqbIdkXas 160 2017-01-21T04:42:08.000Z 2026-10-22T17:43:41.794Z https://longevityharbor.com/en/watch/UuoXQBCicA4 LIVE AMA: Longevity Scientists Answer Your Health & Longevity Questions LIVE https://i.ytimg.com/vi/UuoXQBCicA4/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan In this episode, Matt and Brian Kennedy delve into the potential benefits and side effects of interventions like Rapamycin, the role of biomarkers, and optimal approaches to enhancing healthspan and cognitive function. Together they highlight the challenges of supplement use, aging research methodologies, and regulatory hurdles like the FDA’s stance on aging. They address emerging ideas such as leveraging AI for aging research, the importance of lifestyle factors like diet and sleep, and the need for actionable biomarkers. The session is a candid exchange of expert opinions, tackling scientific controversies and practical strategies for healthy aging. 00:02:33 - What are the potential side effects of Rapamycin, such as on blood lipids or blood sugar? 00:04:22 - How can diet and lifestyle changes enhance cognitive performance? 00:06:09 - What is your favorite biomarker for studying human aging? 00:09:46 - Why do you recommend against taking many supplements at once? 00:13:52 - Is there legitimacy to the idea that aging accelerates at certain ages, like 44 and 60, and does this influence the timing of interventions like Rapamycin? 00:18:34 - When do you think drugs targeting healthspan or lifespan will get regulatory approval for general use? 00:21:38 - Does the FDA's classification of aging as not a disease hinder progress for gero-therapeutics? 00:24:25 - Why are autoimmune diseases becoming more common, and could Rapamycin help with such conditions? 00:27:05 - Is there something you two strongly disagree on regarding aging science or interventions? 00:30:46 - Does NAD+ supplementation meaningfully affect aging, and how should it be delivered? 00:33:32 - What other factors besides diet, exercise, and sleep are vital for functional, healthy aging? 00:37:13 - How important are circadian rhythms and sunlight exposure for longevity, and how do you incorporate this into your routine? 00:39:19 - How should one approach the dosing and timing of Rapamycin for https://www.youtube-nocookie.com/embed/UuoXQBCicA4 5929 2024-12-31T15:07:52.000Z 2026-10-22T19:54:20.491Z https://longevityharbor.com/de/watch/UuoXQBCicA4 LIVE AMA: Longevity Scientists Answer Your Health & Longevity Questions LIVE https://i.ytimg.com/vi/UuoXQBCicA4/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan In this episode, Matt and Brian Kennedy delve into the potential benefits and side effects of interventions like Rapamycin, the role of biomarkers, and optimal approaches to enhancing healthspan and cognitive function. Together they highlight the challenges of supplement use, aging research methodologies, and regulatory hurdles like the FDA’s stance on aging. They address emerging ideas such as leveraging AI for aging research, the importance of lifestyle factors like diet and sleep, and the need for actionable biomarkers. The session is a candid exchange of expert opinions, tackling scientific controversies and practical strategies for healthy aging. 00:02:33 - What are the potential side effects of Rapamycin, such as on blood lipids or blood sugar? 00:04:22 - How can diet and lifestyle changes enhance cognitive performance? 00:06:09 - What is your favorite biomarker for studying human aging? 00:09:46 - Why do you recommend against taking many supplements at once? 00:13:52 - Is there legitimacy to the idea that aging accelerates at certain ages, like 44 and 60, and does this influence the timing of interventions like Rapamycin? 00:18:34 - When do you think drugs targeting healthspan or lifespan will get regulatory approval for general use? 00:21:38 - Does the FDA's classification of aging as not a disease hinder progress for gero-therapeutics? 00:24:25 - Why are autoimmune diseases becoming more common, and could Rapamycin help with such conditions? 00:27:05 - Is there something you two strongly disagree on regarding aging science or interventions? 00:30:46 - Does NAD+ supplementation meaningfully affect aging, and how should it be delivered? 00:33:32 - What other factors besides diet, exercise, and sleep are vital for functional, healthy aging? 00:37:13 - How important are circadian rhythms and sunlight exposure for longevity, and how do you incorporate this into your routine? 00:39:19 - How should one approach the dosing and timing of Rapamycin for https://www.youtube-nocookie.com/embed/UuoXQBCicA4 5929 2024-12-31T15:07:52.000Z 2026-10-22T19:54:20.491Z https://longevityharbor.com/en/watch/Uzd_W6j7UNw Fasten & Langlebigkeit: Was wirklich im Körper passiert? https://i.ytimg.com/vi/Uzd_W6j7UNw/hqdefault.jpg Stell dir vor, dein Körper wäre eine Fabrik, die seit 40 Jahren ohne Pause läuft. 🏭 Keine Wartung, kein Putztrupp – stattdessen sammelt sich überall zellulärer Müll an, die Zahnräder knirschen und das Chaos regiert. 📉 Genau das passiert bei unserer modernen Ernährungsweise, in der wir ständig essen und snacken. Deine Zellen sind im dauerhaften "Bau-Modus", kommen aber nie dazu, zu reparieren. Doch es gibt einen biologischen Schalter, der alles verändert: Er stoppt den Verfall, programmiert deine Zellen auf "Jung" und lässt dein Gehirn mit echtem Premium-Treibstoff laufen. 🧠✨ Die meisten Menschen geben kurz vor der magischen Grenze auf, weil sie das erste Hungergefühl für einen Notfall halten. Erfahre in diesem Video, was passiert, wenn du diese Barriere überwindest, wie dein Körper das "Recyclingprogramm" (Autophagie) startet und warum du beim Fasten keine Muskeln verlierst, sondern zum schärfsten Jäger deiner selbst wirst. 💪🔥 Es geht nicht nur ums Abnehmen – es geht darum, die biologische Uhr zurückzudrehen! ⏳🚀 NEU: Du willst starten, weißt aber nicht wie? Das ByeBye Bauch Rezeptbuch ist da!🥑📖 👉 https://start.byebyebauch.de/buch/ Du liest lieber als zu schauen?📖✨ Kein Problem! Alle unsere Videos findest du auch zum Nachlesen auf dem Blog 👉 https://byebyebauch.de 🖥️✍️ Dort bekommst du die wichtigsten Infos nochmal übersichtlich zusammengefasst – perfekt, wenn du etwas nachschlagen oder in Ruhe lesen möchtest. 🥗🔥 Schau gern vorbei und entdecke noch mehr Tipps rund um Ernährung, Abnehmen & Gesundheit! 💪🍏 https://www.youtube-nocookie.com/embed/Uzd_W6j7UNw 1269 2026-03-11T18:09:06.000Z 2026-10-22T19:32:30.785Z https://longevityharbor.com/de/watch/Uzd_W6j7UNw Fasten & Langlebigkeit: Was wirklich im Körper passiert? https://i.ytimg.com/vi/Uzd_W6j7UNw/hqdefault.jpg Stell dir vor, dein Körper wäre eine Fabrik, die seit 40 Jahren ohne Pause läuft. 🏭 Keine Wartung, kein Putztrupp – stattdessen sammelt sich überall zellulärer Müll an, die Zahnräder knirschen und das Chaos regiert. 📉 Genau das passiert bei unserer modernen Ernährungsweise, in der wir ständig essen und snacken. Deine Zellen sind im dauerhaften "Bau-Modus", kommen aber nie dazu, zu reparieren. Doch es gibt einen biologischen Schalter, der alles verändert: Er stoppt den Verfall, programmiert deine Zellen auf "Jung" und lässt dein Gehirn mit echtem Premium-Treibstoff laufen. 🧠✨ Die meisten Menschen geben kurz vor der magischen Grenze auf, weil sie das erste Hungergefühl für einen Notfall halten. Erfahre in diesem Video, was passiert, wenn du diese Barriere überwindest, wie dein Körper das "Recyclingprogramm" (Autophagie) startet und warum du beim Fasten keine Muskeln verlierst, sondern zum schärfsten Jäger deiner selbst wirst. 💪🔥 Es geht nicht nur ums Abnehmen – es geht darum, die biologische Uhr zurückzudrehen! ⏳🚀 NEU: Du willst starten, weißt aber nicht wie? Das ByeBye Bauch Rezeptbuch ist da!🥑📖 👉 https://start.byebyebauch.de/buch/ Du liest lieber als zu schauen?📖✨ Kein Problem! Alle unsere Videos findest du auch zum Nachlesen auf dem Blog 👉 https://byebyebauch.de 🖥️✍️ Dort bekommst du die wichtigsten Infos nochmal übersichtlich zusammengefasst – perfekt, wenn du etwas nachschlagen oder in Ruhe lesen möchtest. 🥗🔥 Schau gern vorbei und entdecke noch mehr Tipps rund um Ernährung, Abnehmen & Gesundheit! 💪🍏 https://www.youtube-nocookie.com/embed/Uzd_W6j7UNw 1269 2026-03-11T18:09:06.000Z 2026-10-22T19:32:30.785Z https://longevityharbor.com/en/watch/V-iIudVXPNY NAD boosters; NMN and NR: Are they effective? Watch for review of the SCIENCE! https://i.ytimg.com/vi/V-iIudVXPNY/hqdefault.jpg NAD plays many important roles in the human body. As we age NAD levels drop and many studies have shown that low NAD levels contribute to reduced energy, strength and mental acuity. The question is, whether we can replenish falling NAD levels by taking is as a supplement. Here I review the relevant clinical studies to find out. Link to the SHORTER version of this video: https://youtu.be/P-5645n4SA0 https://www.youtube-nocookie.com/embed/V-iIudVXPNY 607 2024-08-01T08:15:17.000Z 2026-10-22T20:11:48.217Z https://longevityharbor.com/de/watch/V-iIudVXPNY NAD boosters; NMN and NR: Are they effective? Watch for review of the SCIENCE! https://i.ytimg.com/vi/V-iIudVXPNY/hqdefault.jpg NAD plays many important roles in the human body. As we age NAD levels drop and many studies have shown that low NAD levels contribute to reduced energy, strength and mental acuity. The question is, whether we can replenish falling NAD levels by taking is as a supplement. Here I review the relevant clinical studies to find out. Link to the SHORTER version of this video: https://youtu.be/P-5645n4SA0 https://www.youtube-nocookie.com/embed/V-iIudVXPNY 607 2024-08-01T08:15:17.000Z 2026-10-22T20:11:48.217Z https://longevityharbor.com/en/watch/V2VU8dLAuxk 7 Foods That Help Protect Your Muscles After 60 💪 | Healthy Aging Tips https://i.ytimg.com/vi/V2VU8dLAuxk/hqdefault.jpg After 60, maintaining muscle becomes increasingly important for strength, balance, mobility, and independence. 💪 In this video, we look at 7 nutritious foods that can help support muscle health as you age—including eggs, beans, fatty fish, Greek yogurt, nuts, leafy greens, and lean meat. But remember: food is only part of the picture. Regular physical activity, especially appropriate strength exercises, and getting enough protein can also support healthy aging. Which of these foods do you eat most often? 👇 Human Body Lab — making your body easier to understand, one video at a time. #HealthyAging #MuscleHealth #Over60 #HealthyEating #Protein #Nutrition #HumanBodyLab https://www.youtube-nocookie.com/embed/V2VU8dLAuxk 115 2026-09-23T12:04:43.000Z 2026-10-22T20:11:49.438Z https://longevityharbor.com/de/watch/V2VU8dLAuxk 7 Foods That Help Protect Your Muscles After 60 💪 | Healthy Aging Tips https://i.ytimg.com/vi/V2VU8dLAuxk/hqdefault.jpg After 60, maintaining muscle becomes increasingly important for strength, balance, mobility, and independence. 💪 In this video, we look at 7 nutritious foods that can help support muscle health as you age—including eggs, beans, fatty fish, Greek yogurt, nuts, leafy greens, and lean meat. But remember: food is only part of the picture. Regular physical activity, especially appropriate strength exercises, and getting enough protein can also support healthy aging. Which of these foods do you eat most often? 👇 Human Body Lab — making your body easier to understand, one video at a time. #HealthyAging #MuscleHealth #Over60 #HealthyEating #Protein #Nutrition #HumanBodyLab https://www.youtube-nocookie.com/embed/V2VU8dLAuxk 115 2026-09-23T12:04:43.000Z 2026-10-22T20:11:49.438Z https://longevityharbor.com/en/watch/V2WseTCJ0Xo Über 10 Jahre länger leben! 🔓 Die beste Ernährung für gesundes Altern? https://i.ytimg.com/vi/V2WseTCJ0Xo/hqdefault.jpg Willkommen zu unserem neuesten Video über **gesundes Altern** und **Longevity**! 👴👵 Erfahren Sie, wie Sie durch **Ernährung** und **Lebensstil** Ihr Leben verlängern und **altersbedingte Krankheiten** vermeiden können. Neue wissenschaftliche **Forschungen** zeigen, dass es in unserer Hand liegt, den **Alterungsprozess** positiv zu beeinflussen. In diesem Video enthüllen wir die Geheimnisse der **Longevity Diät**, die auf einem ausgewogenen Verhältnis von **komplexen Kohlenhydraten**, **pflanzlichen Proteinen** und **gesunden Fetten** basiert. Wir erklären, wie **zeitlich begrenztes Essen** und **Fasten** Ihre **Insulinempfindlichkeit** verbessern und das Risiko für **Diabetes** und **Herz-Kreislauf-Erkrankungen** senken können. Entdecken Sie die Vorteile der **Mittelmeer- und DASH-Diät** und lernen Sie, wie Sie **Protein** im Alter optimal dosieren, um **Muskelschwund** vorzubeugen. Neben der **Ernährung** spielen **Bewegung**, ausreichend **Schlaf** und der Verzicht auf **Tabak** eine entscheidende Rolle für ein **gesundes Leben**. **Experten** betonen, dass **Genetik** und **Lebensstil** Hand in Hand gehen. Eine aktuelle **Studie** aus Großbritannien zeigt, dass **gesunde Ernährung** Ihre **Lebenserwartung** um bis zu 10 Jahre verlängern kann! Starten Sie noch heute mit kleinen Schritten in ein **gesünderes Leben**! 🌱 **Timestamps:** 00:00 - Gesundes Altern 00:18 - Diät Grundlagen 00:39 - Diät Zusammensetzung 01:00 - Diät Vorteile 01:18 - Essen Timing 01:40 - Diätformen Fokus 02:05 - Mittelmeer DASH 02:23 - Protein Balance 02:45 - Gesunder Lebensstil 03:07 - Gesundes Leben 03:29 - Abschluss Botschaft **Key Takeaways:** * ✨ **Longevity Diät:** 45-60% komplexe Kohlenhydrate, 10-15% pflanzliche Proteine, 30% gesunde Fette. * ⏱️ **Zeitlich begrenztes Essen:** Verbessert Insulinempfindlichkeit. * 🥗 **Mittelmeer- & DASH-Diät:** Schützen Herz und Gehirn. * 💪 **Protein-Balance:** Wichtig für Muskeln im Alter. * 🚶‍♀️ **Ganzheitlicher Ansatz:** Ernährung + Lebensstil = Gesundes Al https://www.youtube-nocookie.com/embed/V2WseTCJ0Xo 245 2025-05-26T10:15:05.000Z 2026-10-22T18:43:10.833Z https://longevityharbor.com/de/watch/V2WseTCJ0Xo Über 10 Jahre länger leben! 🔓 Die beste Ernährung für gesundes Altern? https://i.ytimg.com/vi/V2WseTCJ0Xo/hqdefault.jpg Willkommen zu unserem neuesten Video über **gesundes Altern** und **Longevity**! 👴👵 Erfahren Sie, wie Sie durch **Ernährung** und **Lebensstil** Ihr Leben verlängern und **altersbedingte Krankheiten** vermeiden können. Neue wissenschaftliche **Forschungen** zeigen, dass es in unserer Hand liegt, den **Alterungsprozess** positiv zu beeinflussen. In diesem Video enthüllen wir die Geheimnisse der **Longevity Diät**, die auf einem ausgewogenen Verhältnis von **komplexen Kohlenhydraten**, **pflanzlichen Proteinen** und **gesunden Fetten** basiert. Wir erklären, wie **zeitlich begrenztes Essen** und **Fasten** Ihre **Insulinempfindlichkeit** verbessern und das Risiko für **Diabetes** und **Herz-Kreislauf-Erkrankungen** senken können. Entdecken Sie die Vorteile der **Mittelmeer- und DASH-Diät** und lernen Sie, wie Sie **Protein** im Alter optimal dosieren, um **Muskelschwund** vorzubeugen. Neben der **Ernährung** spielen **Bewegung**, ausreichend **Schlaf** und der Verzicht auf **Tabak** eine entscheidende Rolle für ein **gesundes Leben**. **Experten** betonen, dass **Genetik** und **Lebensstil** Hand in Hand gehen. Eine aktuelle **Studie** aus Großbritannien zeigt, dass **gesunde Ernährung** Ihre **Lebenserwartung** um bis zu 10 Jahre verlängern kann! Starten Sie noch heute mit kleinen Schritten in ein **gesünderes Leben**! 🌱 **Timestamps:** 00:00 - Gesundes Altern 00:18 - Diät Grundlagen 00:39 - Diät Zusammensetzung 01:00 - Diät Vorteile 01:18 - Essen Timing 01:40 - Diätformen Fokus 02:05 - Mittelmeer DASH 02:23 - Protein Balance 02:45 - Gesunder Lebensstil 03:07 - Gesundes Leben 03:29 - Abschluss Botschaft **Key Takeaways:** * ✨ **Longevity Diät:** 45-60% komplexe Kohlenhydrate, 10-15% pflanzliche Proteine, 30% gesunde Fette. * ⏱️ **Zeitlich begrenztes Essen:** Verbessert Insulinempfindlichkeit. * 🥗 **Mittelmeer- & DASH-Diät:** Schützen Herz und Gehirn. * 💪 **Protein-Balance:** Wichtig für Muskeln im Alter. * 🚶‍♀️ **Ganzheitlicher Ansatz:** Ernährung + Lebensstil = Gesundes Al https://www.youtube-nocookie.com/embed/V2WseTCJ0Xo 245 2025-05-26T10:15:05.000Z 2026-10-22T18:43:10.833Z https://longevityharbor.com/en/watch/V4wumYo-yWs Dr. Rhonda Patrick's daily smoothie: five ingredients and food questions https://i.ytimg.com/vi/V4wumYo-yWs/hqdefault.jpg In this video description, Dr. Rhonda Patrick lists the five ingredients in her daily smoothie and asks whether blueberries, kale, avocado and plastic blenders affect nutrients or health. The description gives no results. https://www.youtube-nocookie.com/embed/V4wumYo-yWs 904 2026-06-28T15:02:44.000Z 2026-10-22T23:46:24.308Z https://longevityharbor.com/de/watch/V4wumYo-yWs Dr. Rhonda Patricks täglicher Smoothie: fünf Zutaten und Lebensmittelfragen https://i.ytimg.com/vi/V4wumYo-yWs/hqdefault.jpg In dieser Videobeschreibung nennt Dr. Rhonda Patrick die fünf Zutaten ihres täglichen Smoothies und fragt, ob Blaubeeren, Grünkohl, Avocado und Plastikmixer Nährstoffe oder Gesundheit beeinflussen. Ergebnisse nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/V4wumYo-yWs 904 2026-06-28T15:02:44.000Z 2026-10-22T23:46:24.308Z https://longevityharbor.com/en/watch/V87x8H2mQ5U Video description: breakfast protein for muscle in adults over 60 https://i.ytimg.com/vi/V87x8H2mQ5U/hqdefault.jpg The description says the video covers why breakfast is often the lowest-protein meal for older adults, why muscle needs a stronger protein signal after sixty, what research says and does not say about protein timing, eggs as an easy anchor, and a three-step plan: Anchor, Add, Activate. https://www.youtube-nocookie.com/embed/V87x8H2mQ5U 541 2026-10-20T07:27:37.000Z 2026-10-22T21:10:58.636Z https://longevityharbor.com/de/watch/V87x8H2mQ5U Videobeschreibung: Protein zum Frühstück für Muskeln bei Erwachsenen über 60 https://i.ytimg.com/vi/V87x8H2mQ5U/hqdefault.jpg Laut Beschreibung behandelt das Video, warum das Frühstück bei älteren Erwachsenen oft die proteinärmste Mahlzeit ist, warum Muskeln nach sechzig ein stärkeres Proteinsignal brauchen, was die Forschung zum Protein-Timing sagt und nicht sagt, Eier als einfachen Anker und einen Dreischritt-Plan: Anchor, Add, Activate. https://www.youtube-nocookie.com/embed/V87x8H2mQ5U 541 2026-10-20T07:27:37.000Z 2026-10-22T21:10:58.636Z https://longevityharbor.com/en/watch/VEHCo7brJ4g Seneszenzforschung: Verjüngung? Die bahnbrechende Studie! #shorts https://i.ytimg.com/vi/VEHCo7brJ4g/hqdefault.jpg Viele fragen sich, woher wir das wissen. Die Seneszenzforschung erlebte von 2011-2015 ihren Durchbruch. Eine Studie an der Mayo Klinik zeigte, dass das Entfernen seneszenter Zellen bei Mäusen Alterung verlangsamt und Organfunktionen verbessert. Anzeige/AD #Zellalterung #Seneszenz #Verjüngung #Forschung #Gesundheit https://www.youtube-nocookie.com/embed/VEHCo7brJ4g 93 2025-10-09T16:55:47.000Z 2026-10-22T19:21:22.018Z https://longevityharbor.com/de/watch/VEHCo7brJ4g Seneszenzforschung: Verjüngung? Die bahnbrechende Studie! #shorts https://i.ytimg.com/vi/VEHCo7brJ4g/hqdefault.jpg Viele fragen sich, woher wir das wissen. Die Seneszenzforschung erlebte von 2011-2015 ihren Durchbruch. Eine Studie an der Mayo Klinik zeigte, dass das Entfernen seneszenter Zellen bei Mäusen Alterung verlangsamt und Organfunktionen verbessert. Anzeige/AD #Zellalterung #Seneszenz #Verjüngung #Forschung #Gesundheit https://www.youtube-nocookie.com/embed/VEHCo7brJ4g 93 2025-10-09T16:55:47.000Z 2026-10-22T19:21:22.018Z https://longevityharbor.com/en/watch/VJJ3mWEAFNs Scientist at 50 describes her own aging protocol in a video description https://i.ytimg.com/vi/VJJ3mWEAFNs/hqdefault.jpg The description says a scientist with a PhD in molecular and cellular oncology explains biological versus chronological age, the hallmarks of aging, epigenetics and her own DunedinPACE result, and outlines a personal protocol with testing and peptides. She calls it educational self-experimentation, not medical advice. https://www.youtube-nocookie.com/embed/VJJ3mWEAFNs 1272 2026-09-28T17:00:04.000Z 2026-10-22T21:39:29.688Z https://longevityharbor.com/de/watch/VJJ3mWEAFNs Wissenschaftlerin mit 50 beschreibt im Videobeschreibungstext ihr eigenes Alternsprotokoll https://i.ytimg.com/vi/VJJ3mWEAFNs/hqdefault.jpg Laut Beschreibung erklärt eine Wissenschaftlerin mit Doktortitel in molekularer und zellulärer Onkologie biologisches versus chronologisches Alter, die Hallmarks des Alterns, Epigenetik und ihr eigenes DunedinPACE-Ergebnis und skizziert ein persönliches Protokoll mit Tests und Peptiden. Sie nennt es edukative Selbstexperimente, keine medizinische Beratung. https://www.youtube-nocookie.com/embed/VJJ3mWEAFNs 1272 2026-09-28T17:00:04.000Z 2026-10-22T21:39:29.688Z https://longevityharbor.com/en/watch/VYVjE6HEgy0 Michael Hall (University of Basel): The Story of TOR (Target of Rapamycin) https://i.ytimg.com/vi/VYVjE6HEgy0/hqdefault.jpg https://www.ibiology.org/cell-biology/target-rapamycin/ Michael Hall describes the discovery of TOR (Target of Rapamycin) protein, the key controller of the size of both individual cells and entire organisms.   Talk Overview: TOR, the Target of Rapamycin, is now known to be a central controller of cell, tissue and organism growth and an important molecule in many human diseases including cancer, cardiac hypertrophy, diabetes and obesity.  Michael Hall explains how the fortuitous decision, in 1991, to investigate the action of rapamycin in yeast, led to the discovery of TOR. Speaker Biography: Dr. Michael Hall received his PhD from Harvard and was a post-doctoral fellow at the Institut Pasteur and the University of California, San Francisco.  He joined the Biozentrum of the University of Basel in 1987 and where he is currently a Professor of Biochemistry. Hall’s lab continues to study TOR and its role in development, aging and disease. Hall has received numerous awards in recognition of his pioneering work.  Recent honors include the Louis-Jeantet Prize for Medicine (2009), the Marcel Benoist Prize (2012), the Breakthrough Prize (2014), the Canada Gairdner Award (2015), and the Albert Lasker Basic Medical Research Award (2017).  Hall is also a member of the US National Academy of Sciences. Learn more about Dr. Hall’s research here: https://www.biozentrum.unibas.ch/research/groups-platforms/overview/unit/hall/ https://www.youtube-nocookie.com/embed/VYVjE6HEgy0 1479 2017-09-06T17:16:12.000Z 2026-10-22T17:43:41.811Z https://longevityharbor.com/de/watch/VYVjE6HEgy0 Michael Hall (University of Basel): The Story of TOR (Target of Rapamycin) https://i.ytimg.com/vi/VYVjE6HEgy0/hqdefault.jpg https://www.ibiology.org/cell-biology/target-rapamycin/ Michael Hall describes the discovery of TOR (Target of Rapamycin) protein, the key controller of the size of both individual cells and entire organisms.   Talk Overview: TOR, the Target of Rapamycin, is now known to be a central controller of cell, tissue and organism growth and an important molecule in many human diseases including cancer, cardiac hypertrophy, diabetes and obesity.  Michael Hall explains how the fortuitous decision, in 1991, to investigate the action of rapamycin in yeast, led to the discovery of TOR. Speaker Biography: Dr. Michael Hall received his PhD from Harvard and was a post-doctoral fellow at the Institut Pasteur and the University of California, San Francisco.  He joined the Biozentrum of the University of Basel in 1987 and where he is currently a Professor of Biochemistry. Hall’s lab continues to study TOR and its role in development, aging and disease. Hall has received numerous awards in recognition of his pioneering work.  Recent honors include the Louis-Jeantet Prize for Medicine (2009), the Marcel Benoist Prize (2012), the Breakthrough Prize (2014), the Canada Gairdner Award (2015), and the Albert Lasker Basic Medical Research Award (2017).  Hall is also a member of the US National Academy of Sciences. Learn more about Dr. Hall’s research here: https://www.biozentrum.unibas.ch/research/groups-platforms/overview/unit/hall/ https://www.youtube-nocookie.com/embed/VYVjE6HEgy0 1479 2017-09-06T17:16:12.000Z 2026-10-22T17:43:41.811Z https://longevityharbor.com/en/watch/VZVFRA0yIJ0 Biological age tests: what epigenetic clocks measure and whether diet trials changed them https://i.ytimg.com/vi/VZVFRA0yIJ0/hqdefault.jpg The description says this episode examines what biological age and epigenetic clocks measure, how they were checked against disease and mortality, and whether calorie restriction and diet quality changed them in randomized trials. https://www.youtube-nocookie.com/embed/VZVFRA0yIJ0 1277 2026-10-01T16:13:20.000Z 2026-10-22T21:33:28.032Z https://longevityharbor.com/de/watch/VZVFRA0yIJ0 Biologische Alterstests: Was epigenetische Uhren messen und ob Ernährungstests sie veränderten https://i.ytimg.com/vi/VZVFRA0yIJ0/hqdefault.jpg Laut Beschreibung untersucht diese Folge, was biologisches Alter und epigenetische Uhren messen, wie sie an Krankheit und Sterblichkeit geprüft wurden und ob Kalorienrestriktion und Ernährungsqualität sie in randomisierten Studien veränderten. https://www.youtube-nocookie.com/embed/VZVFRA0yIJ0 1277 2026-10-01T16:13:20.000Z 2026-10-22T21:33:28.032Z https://longevityharbor.com/en/watch/V_xz_eUvSTE PI3K–Akt–mTOR pathway explained in an animation: growth, survival and autophagy https://i.ytimg.com/vi/V_xz_eUvSTE/hqdefault.jpg The description says this animation walks through the PI3K–Akt–mTOR signaling pathway step by step, from growth factors binding receptor tyrosine kinases to mTOR's role in protein synthesis, cell growth, survival and autophagy. https://www.youtube-nocookie.com/embed/V_xz_eUvSTE 139 2026-09-05T09:08:49.000Z 2026-10-22T22:28:35.544Z https://longevityharbor.com/de/watch/V_xz_eUvSTE PI3K–Akt–mTOR-Weg in einer Animation erklärt: Wachstum, Überleben und Autophagie https://i.ytimg.com/vi/V_xz_eUvSTE/hqdefault.jpg Laut Beschreibung führt diese Animation den PI3K–Akt–mTOR-Signalweg Schritt für Schritt durch: von Wachstumsfaktoren, die an Rezeptor-Tyrosinkinasen binden, bis zur Rolle von mTOR bei Proteinsynthese, Zellwachstum, Überleben und Autophagie. https://www.youtube-nocookie.com/embed/V_xz_eUvSTE 139 2026-09-05T09:08:49.000Z 2026-10-22T22:28:35.544Z https://longevityharbor.com/en/watch/Vg3YDhQPEJw Conference talk on SIRT6, DNA repair, the dark genome and inflammation in ageing https://i.ytimg.com/vi/Vg3YDhQPEJw/hqdefault.jpg In this conference description, Professors Gorbunova and Seluanov present research on DNA repair, SIRT6, fucoidan, inflammageing and LINE-1 elements; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/Vg3YDhQPEJw 2643 2026-10-07T08:46:36.000Z 2026-10-22T21:15:15.985Z https://longevityharbor.com/de/watch/Vg3YDhQPEJw Konferenzvortrag zu SIRT6, DNA-Reparatur, dunklem Genom und Entzündung beim Altern https://i.ytimg.com/vi/Vg3YDhQPEJw/hqdefault.jpg In dieser Konferenzbeschreibung stellen die Professorinnen und Professoren Gorbunova und Seluanov Forschung zu DNA-Reparatur, SIRT6, Fucoidan, Inflammageing und LINE-1-Elementen vor; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/Vg3YDhQPEJw 2643 2026-10-07T08:46:36.000Z 2026-10-22T21:15:15.985Z https://longevityharbor.com/en/watch/VhhQrb38CMs The Science of Eternal Youth | Can We Stop Aging? https://i.ytimg.com/vi/VhhQrb38CMs/hqdefault.jpg What if aging wasn’t inevitable? In this full documentary, we explore the cutting-edge science of aging, from telomeres and NAD+ to sirtuins and cellular senescence. Discover how scientists are unlocking the secrets of longevity, studying animals that defy time like the immortal jellyfish and century-old whales, and testing revolutionary ideas such as senolytics, gene editing (CRISPR), and anti-aging molecules. This documentary dives deep into the quest for the fountain of youth, blending history, biology, and futuristic science. Is eternal youth possible, or just a dream? 🔔 Subscribe for more documentaries on longevity, human biology, anti-aging research, and the future of health."* https://www.youtube-nocookie.com/embed/VhhQrb38CMs 442 2025-09-14T16:38:52.000Z 2026-10-22T19:43:47.878Z https://longevityharbor.com/de/watch/VhhQrb38CMs The Science of Eternal Youth | Can We Stop Aging? https://i.ytimg.com/vi/VhhQrb38CMs/hqdefault.jpg What if aging wasn’t inevitable? In this full documentary, we explore the cutting-edge science of aging, from telomeres and NAD+ to sirtuins and cellular senescence. Discover how scientists are unlocking the secrets of longevity, studying animals that defy time like the immortal jellyfish and century-old whales, and testing revolutionary ideas such as senolytics, gene editing (CRISPR), and anti-aging molecules. This documentary dives deep into the quest for the fountain of youth, blending history, biology, and futuristic science. Is eternal youth possible, or just a dream? 🔔 Subscribe for more documentaries on longevity, human biology, anti-aging research, and the future of health."* https://www.youtube-nocookie.com/embed/VhhQrb38CMs 442 2025-09-14T16:38:52.000Z 2026-10-22T19:43:47.878Z https://longevityharbor.com/en/watch/VlQ2fnezKy8 Why Your Aging Parent Wakes Up at 3 AM: The Real Biological Science of Sleep Explained. https://i.ytimg.com/vi/VlQ2fnezKy8/hqdefault.jpg Welcome to The Aging Prequel Science, your Calm Science Corner. Link Video: https://youtu.be/VlQ2fnezKy8Waking up at 3 AM? It's exhausting for you and your aging parent. This isn't just "bad sleep"—it's a biological change in their sleep architecture. We explain the science of circadian rhythm shifts (SCN), melatonin decline, and the loss of deep sleep. Understand why elderly sleep patterns change and what you can do to help. #Sleep #Aging #Caregiving https://www.youtube-nocookie.com/embed/VlQ2fnezKy8 540 2025-11-22T23:30:23.000Z 2026-10-22T18:54:02.156Z https://longevityharbor.com/de/watch/VlQ2fnezKy8 Why Your Aging Parent Wakes Up at 3 AM: The Real Biological Science of Sleep Explained. https://i.ytimg.com/vi/VlQ2fnezKy8/hqdefault.jpg Welcome to The Aging Prequel Science, your Calm Science Corner. Link Video: https://youtu.be/VlQ2fnezKy8Waking up at 3 AM? It's exhausting for you and your aging parent. This isn't just "bad sleep"—it's a biological change in their sleep architecture. We explain the science of circadian rhythm shifts (SCN), melatonin decline, and the loss of deep sleep. Understand why elderly sleep patterns change and what you can do to help. #Sleep #Aging #Caregiving https://www.youtube-nocookie.com/embed/VlQ2fnezKy8 540 2025-11-22T23:30:23.000Z 2026-10-22T18:54:02.156Z https://longevityharbor.com/en/watch/VtsvVKUPOJA 7 Lebensmittel für ein gesundes Gehirn | Diese Ernährung unterstützt Ihr Gedächtnis https://i.ytimg.com/vi/VtsvVKUPOJA/hqdefault.jpg Welche Lebensmittel sind gut für das Gehirn? In diesem Video zeigen wir Ihnen 7 Lebensmittel für ein gesundes Gehirn, die Gedächtnis und Konzentration unterstützen können. Erfahren Sie, welche Rolle Beeren, Fisch, grünes Blattgemüse, Nüsse, Olivenöl, Hülsenfrüchte und Vollkornprodukte für Gehirngesundheit und gesundes Altern ab 50 spielen können. In diesem Video sprechen wir über: 🫐 Beeren 🐟 Fetter Fisch 🥬 Grünes Blattgemüse 🥜 Nüsse 🫒 Olivenöl 🫘 Hülsenfrüchte 🌾 Vollkornprodukte Dabei geht es nicht um ein einzelnes „Wundermittel“ für das Gehirn. Eine gesunde Ernährung funktioniert nicht so einfach. Entscheidend ist vielmehr das gesamte Ernährungsmuster und die Gewohnheiten, die wir über viele Jahre beibehalten. Eine ausgewogene Ernährung mit viel Gemüse, Obst, Vollkornprodukten, Hülsenfrüchten, Nüssen, Fisch und gesunden Fetten kann Teil eines gesunden Lebensstils sein. Wenn Sie gesund älter werden, geistig klar bleiben und möglichst lange selbstständig leben möchten, finden Sie bei VitalMöglich verständliche Informationen zu: 🧠 Gehirn & Gedächtnis 🥗 Ernährung & Gesundheit 😴 Schlaf & Energie 💪 Kraft & Bewegung 🌿 Gesundes Altern ab 50 Abonnieren Sie VitalMöglich für weitere Videos rund um Gehirngesundheit, Ernährung, gesundes Altern und ein aktives Leben. Für alle, die nicht nur älter werden, sondern gut älter werden wollen. #Gehirngesundheit #GesundÄlterWerden #ErnährungAb50 #VitalMöglich https://www.youtube-nocookie.com/embed/VtsvVKUPOJA 645 2026-10-09T14:00:04.000Z 2026-10-22T18:43:10.898Z https://longevityharbor.com/de/watch/VtsvVKUPOJA 7 Lebensmittel für ein gesundes Gehirn | Diese Ernährung unterstützt Ihr Gedächtnis https://i.ytimg.com/vi/VtsvVKUPOJA/hqdefault.jpg Welche Lebensmittel sind gut für das Gehirn? In diesem Video zeigen wir Ihnen 7 Lebensmittel für ein gesundes Gehirn, die Gedächtnis und Konzentration unterstützen können. Erfahren Sie, welche Rolle Beeren, Fisch, grünes Blattgemüse, Nüsse, Olivenöl, Hülsenfrüchte und Vollkornprodukte für Gehirngesundheit und gesundes Altern ab 50 spielen können. In diesem Video sprechen wir über: 🫐 Beeren 🐟 Fetter Fisch 🥬 Grünes Blattgemüse 🥜 Nüsse 🫒 Olivenöl 🫘 Hülsenfrüchte 🌾 Vollkornprodukte Dabei geht es nicht um ein einzelnes „Wundermittel“ für das Gehirn. Eine gesunde Ernährung funktioniert nicht so einfach. Entscheidend ist vielmehr das gesamte Ernährungsmuster und die Gewohnheiten, die wir über viele Jahre beibehalten. Eine ausgewogene Ernährung mit viel Gemüse, Obst, Vollkornprodukten, Hülsenfrüchten, Nüssen, Fisch und gesunden Fetten kann Teil eines gesunden Lebensstils sein. Wenn Sie gesund älter werden, geistig klar bleiben und möglichst lange selbstständig leben möchten, finden Sie bei VitalMöglich verständliche Informationen zu: 🧠 Gehirn & Gedächtnis 🥗 Ernährung & Gesundheit 😴 Schlaf & Energie 💪 Kraft & Bewegung 🌿 Gesundes Altern ab 50 Abonnieren Sie VitalMöglich für weitere Videos rund um Gehirngesundheit, Ernährung, gesundes Altern und ein aktives Leben. Für alle, die nicht nur älter werden, sondern gut älter werden wollen. #Gehirngesundheit #GesundÄlterWerden #ErnährungAb50 #VitalMöglich https://www.youtube-nocookie.com/embed/VtsvVKUPOJA 645 2026-10-09T14:00:04.000Z 2026-10-22T18:43:10.898Z https://longevityharbor.com/en/watch/VyJawp4cGHQ Daily multivitamin slowed epigenetic aging in COSMOS trial https://i.ytimg.com/vi/VyJawp4cGHQ/hqdefault.jpg In the COSMOS randomized trial, 958 adults averaging 70 took a daily multivitamin or placebo for two years; the multivitamin group aged more slowly on all five epigenetic clocks, significantly on two. The creator calls the effect small and the clocks surrogate markers. https://www.youtube-nocookie.com/embed/VyJawp4cGHQ 95 2026-08-14T14:20:05.000Z 2026-10-22T23:01:34.712Z https://longevityharbor.com/de/watch/VyJawp4cGHQ Tägliches Multivitamin verlangsamte epigenetisches Altern in COSMOS-Studie https://i.ytimg.com/vi/VyJawp4cGHQ/hqdefault.jpg In der randomisierten COSMOS-Studie nahmen 958 Erwachsene mit Durchschnittsalter 70 zwei Jahre lang täglich ein Multivitamin oder Placebo; die Multivitamingruppe alterte auf allen fünf epigenetischen Uhren langsamer, signifikant auf zwei. Der Ersteller nennt den Effekt klein und die Uhren Ersatzmarker. https://www.youtube-nocookie.com/embed/VyJawp4cGHQ 95 2026-08-14T14:20:05.000Z 2026-10-22T23:01:34.712Z https://longevityharbor.com/en/watch/W1WdLoLSMNY Video description lists five frailty signs and discusses building resilience https://i.ytimg.com/vi/W1WdLoLSMNY/hqdefault.jpg The description says frailty is a gradual loss of resilience that can start earlier than expected and lists five signs of frailty or pre-frailty, including unintentional weight loss and reduced grip strength. https://www.youtube-nocookie.com/embed/W1WdLoLSMNY 97 2026-05-15T14:53:15.000Z 2026-10-23T00:45:51.360Z https://longevityharbor.com/de/watch/W1WdLoLSMNY Videobeschreibung nennt fünf Gebrechlichkeitszeichen und diskutiert Resilienzaufbau https://i.ytimg.com/vi/W1WdLoLSMNY/hqdefault.jpg Die Beschreibung bezeichnet Gebrechlichkeit als allmählichen Verlust der Resilienz, der früher als erwartet beginnen kann, und nennt fünf Zeichen von Gebrechlichkeit oder Vor-Gebrechlichkeit, darunter unbeabsichtigter Gewichtsverlust und verminderte Griffkraft. https://www.youtube-nocookie.com/embed/W1WdLoLSMNY 97 2026-05-15T14:53:15.000Z 2026-10-23T00:45:51.360Z https://longevityharbor.com/en/watch/W21pjbZIR3s What You ACTUALLY Need To Know About MTOR And Aging | MTOR's Role In Aging And Longevity https://i.ytimg.com/vi/W21pjbZIR3s/hqdefault.jpg CE COURSES FOR PROFESSIONALS: https://bit.ly/dra-continuingeducation Dr. A discusses the mTOR pathway, its function in cell regulation, and its connection to health and longevity. Learn about rapamycin, natural ways to modulate mTOR, and the balance needed for optimal well-being. ____________________________ CHAPTERS 00:00 Introduction 01:12 The History of mTOR Discovery 03:02 Role of mTOR in Cellular Health 03:39 Uses of Rapamycin 04:55 mTOR Pathway Modulation 07:20 Natural mTOR Regulators 08:38 mTOR, Nutrition, and Longevity Medicine ___________________________ This video is NOT sponsored. Connect with Dr. Anderson ~ Dr A YouTube Channel: https://www.youtube.com/channel/UC1FLIaKDzkU5Z0knDYYKyPQ Dr A Instagram: https://www.instagram.com/draonline/ Continuing Education for Professionals: consultdranderson.com Dr A Links: https://linktr.ee/DrAonline Dr A Website: https://dranow.com/ Methylene Blue CE Webinar: https://www.consultdranderson.com/product/107-methylene-blue/ Consult with Dr. A- https://www.consultdranderson.com/product/vitamin-c-webinar-bundle/ ____________________________ #integrativemedicine #functionalmedicine #doctorsofinstagram #doctor #nmd #nd #naturopathicdoctor #naturopathy #microbiology #microbiome #biofilms ____________________________ INTEGRATIVE MEDICINE REFERRAL LINKS (Use these to find providers.) [For your reference only – no referral or implication of professional superiority is claimed or intended.] NAEM (Environmental Medicine) Providers: https://envmedicine.com/find-a-provider/ US Naturopathic Physicians: https://naturopathic.org/search/default.asp?m=radius Canadian Naturopathic Physicians: https://www.cand.ca/findmynd/ Digestive Specialists: https://www.gastroanp.org/directory Mold and Environmental Illness Referrals: https://drcrista.com/doctor-finder/ Mental Health focus: https://www.psychanp.org/member-directory.html Cancer Focus: https://www.oncanp.org/find-an-nd#!directory/map New Hampshire Naturopathic Physicians [NHAND.org]: http://nhand.org https://www.youtube-nocookie.com/embed/W21pjbZIR3s 677 2025-01-18T14:00:27.000Z 2026-10-22T17:43:41.080Z https://longevityharbor.com/de/watch/W21pjbZIR3s What You ACTUALLY Need To Know About MTOR And Aging | MTOR's Role In Aging And Longevity https://i.ytimg.com/vi/W21pjbZIR3s/hqdefault.jpg CE COURSES FOR PROFESSIONALS: https://bit.ly/dra-continuingeducation Dr. A discusses the mTOR pathway, its function in cell regulation, and its connection to health and longevity. Learn about rapamycin, natural ways to modulate mTOR, and the balance needed for optimal well-being. ____________________________ CHAPTERS 00:00 Introduction 01:12 The History of mTOR Discovery 03:02 Role of mTOR in Cellular Health 03:39 Uses of Rapamycin 04:55 mTOR Pathway Modulation 07:20 Natural mTOR Regulators 08:38 mTOR, Nutrition, and Longevity Medicine ___________________________ This video is NOT sponsored. Connect with Dr. Anderson ~ Dr A YouTube Channel: https://www.youtube.com/channel/UC1FLIaKDzkU5Z0knDYYKyPQ Dr A Instagram: https://www.instagram.com/draonline/ Continuing Education for Professionals: consultdranderson.com Dr A Links: https://linktr.ee/DrAonline Dr A Website: https://dranow.com/ Methylene Blue CE Webinar: https://www.consultdranderson.com/product/107-methylene-blue/ Consult with Dr. A- https://www.consultdranderson.com/product/vitamin-c-webinar-bundle/ ____________________________ #integrativemedicine #functionalmedicine #doctorsofinstagram #doctor #nmd #nd #naturopathicdoctor #naturopathy #microbiology #microbiome #biofilms ____________________________ INTEGRATIVE MEDICINE REFERRAL LINKS (Use these to find providers.) [For your reference only – no referral or implication of professional superiority is claimed or intended.] NAEM (Environmental Medicine) Providers: https://envmedicine.com/find-a-provider/ US Naturopathic Physicians: https://naturopathic.org/search/default.asp?m=radius Canadian Naturopathic Physicians: https://www.cand.ca/findmynd/ Digestive Specialists: https://www.gastroanp.org/directory Mold and Environmental Illness Referrals: https://drcrista.com/doctor-finder/ Mental Health focus: https://www.psychanp.org/member-directory.html Cancer Focus: https://www.oncanp.org/find-an-nd#!directory/map New Hampshire Naturopathic Physicians [NHAND.org]: http://nhand.org https://www.youtube-nocookie.com/embed/W21pjbZIR3s 677 2025-01-18T14:00:27.000Z 2026-10-22T17:43:41.080Z https://longevityharbor.com/en/watch/W33eq5-f1Bc Video description: three proposed cellular strategies against biological aging https://i.ytimg.com/vi/W33eq5-f1Bc/hqdefault.jpg The description says the video presents three strategies said to act most deeply on cell biology, based on studies from 2023 to 2025. It names cellular senescence and autophagy, nutrition as an epigenetic switch, and telomere protection through exercise and stress regulation. https://www.youtube-nocookie.com/embed/W33eq5-f1Bc 1036 2026-05-31T07:15:24.000Z 2026-10-23T00:16:50.174Z https://longevityharbor.com/de/watch/W33eq5-f1Bc Videobeschreibung: drei vorgestellte Zellstrategien gegen biologisches Altern https://i.ytimg.com/vi/W33eq5-f1Bc/hqdefault.jpg Laut Beschreibung stellt das Video drei Strategien vor, die am tiefsten in die Zellbiologie eingreifen sollen, gestützt auf Studien von 2023 bis 2025. Genannt werden zelluläre Seneszenz und Autophagie, Ernährung als epigenetischer Schalter sowie Telomerschutz durch Bewegung und Stressregulation. https://www.youtube-nocookie.com/embed/W33eq5-f1Bc 1036 2026-05-31T07:15:24.000Z 2026-10-23T00:16:50.174Z https://longevityharbor.com/en/watch/W3GcuiswbGc Nir Barzilai at ARDD2025: translating geroscience into gerotherapeutics https://i.ytimg.com/vi/W3GcuiswbGc/hqdefault.jpg According to the description, Nir Barzilai of the Albert Einstein College of Medicine presented at the 12th Aging Research and Drug Discovery meeting on translating geroscience into gerotherapeutics, under the title From Pathways to Patients. https://www.youtube-nocookie.com/embed/W3GcuiswbGc 1466 2026-01-16T13:35:11.000Z 2026-10-23T02:49:33.997Z https://longevityharbor.com/de/watch/W3GcuiswbGc Nir Barzilai bei ARDD2025: Geroscience in Gerotherapeutika übersetzen https://i.ytimg.com/vi/W3GcuiswbGc/hqdefault.jpg Laut Beschreibung sprach Nir Barzilai vom Albert Einstein College of Medicine beim 12. Aging Research and Drug Discovery Meeting darüber, Geroscience in Gerotherapeutika zu übersetzen, unter dem Titel From Pathways to Patients. https://www.youtube-nocookie.com/embed/W3GcuiswbGc 1466 2026-01-16T13:35:11.000Z 2026-10-23T02:49:33.997Z https://longevityharbor.com/en/watch/W3xQ15Fj8eA Epigenetic Clocks, HRV & Hormones: AI Reads Your Aging Blueprint https://i.ytimg.com/vi/W3xQ15Fj8eA/hqdefault.jpg Aging is no longer just something that happens to you—it’s something that can be measured, modeled, and optimized. In this presentation, we explore how to build an AI health agent capable of managing and potentially reversing biological age by synthesizing biomarkers, epigenetic clocks, sleep data, nutrition, genomics, and wearable signals into a closed‑loop longevity system. Modern health technology generates massive volumes of data—blood panels, CGMs, wearables, sleep trackers—but most of it remains siloed and underutilized. The core problem is not data collection. It is intelligent synthesis. This talk outlines how an AI agent becomes the missing layer that can reason across all biological signals simultaneously and translate them into precise, personalized action. In this presentation, you’ll learn: What biological age actually measures—and why it matters more than chronological age How epigenetic clocks, metabolic markers, inflammation, HRV, sleep architecture, and hormones define aging trajectories Why biological age is dynamic and modifiable, not fixed The architecture of an AI longevity agent, including: Multi‑source data ingestion (labs, wearables, genomics) LLM‑based synthesis and causal reasoning Retrieval‑augmented generation (RAG) grounded in peer‑reviewed science Hyper‑personalization using genetics, phenotype history, and feedback loops How closed‑loop intervention systems outperform static health dashboards Practical intervention domains: metabolism, sleep optimization, cognitive vitality, cellular repair, and hormonal architecture A realistic implementation roadmap—from baseline testing to production‑grade AI health agents Unlike consumer health apps, this system treats the individual as N=1, continuously measuring outcomes, updating its internal model, and refining recommendations over time. The goal is not symptom tracking—it is biological age reduction and healthspan optimization. This talk is designed for: AI founders and engineers building agent‑based systems Clinicians and resea https://www.youtube-nocookie.com/embed/W3xQ15Fj8eA 789 2026-03-15T08:37:21.000Z 2026-10-22T18:32:05.918Z https://longevityharbor.com/de/watch/W3xQ15Fj8eA Epigenetic Clocks, HRV & Hormones: AI Reads Your Aging Blueprint https://i.ytimg.com/vi/W3xQ15Fj8eA/hqdefault.jpg Aging is no longer just something that happens to you—it’s something that can be measured, modeled, and optimized. In this presentation, we explore how to build an AI health agent capable of managing and potentially reversing biological age by synthesizing biomarkers, epigenetic clocks, sleep data, nutrition, genomics, and wearable signals into a closed‑loop longevity system. Modern health technology generates massive volumes of data—blood panels, CGMs, wearables, sleep trackers—but most of it remains siloed and underutilized. The core problem is not data collection. It is intelligent synthesis. This talk outlines how an AI agent becomes the missing layer that can reason across all biological signals simultaneously and translate them into precise, personalized action. In this presentation, you’ll learn: What biological age actually measures—and why it matters more than chronological age How epigenetic clocks, metabolic markers, inflammation, HRV, sleep architecture, and hormones define aging trajectories Why biological age is dynamic and modifiable, not fixed The architecture of an AI longevity agent, including: Multi‑source data ingestion (labs, wearables, genomics) LLM‑based synthesis and causal reasoning Retrieval‑augmented generation (RAG) grounded in peer‑reviewed science Hyper‑personalization using genetics, phenotype history, and feedback loops How closed‑loop intervention systems outperform static health dashboards Practical intervention domains: metabolism, sleep optimization, cognitive vitality, cellular repair, and hormonal architecture A realistic implementation roadmap—from baseline testing to production‑grade AI health agents Unlike consumer health apps, this system treats the individual as N=1, continuously measuring outcomes, updating its internal model, and refining recommendations over time. The goal is not symptom tracking—it is biological age reduction and healthspan optimization. This talk is designed for: AI founders and engineers building agent‑based systems Clinicians and resea https://www.youtube-nocookie.com/embed/W3xQ15Fj8eA 789 2026-03-15T08:37:21.000Z 2026-10-22T18:32:05.918Z https://longevityharbor.com/en/watch/W99sFcrdwmE SGLT2 inhibitors, senescence and telomeres: a video description overview https://i.ytimg.com/vi/W99sFcrdwmE/hqdefault.jpg The description says SGLT2 inhibitors, developed to lower blood sugar in type 2 diabetes, may influence hallmarks of aging; it cites a 2024 mouse study on senescent cell clearance and a 2025 human trial on telomere lengthening. https://www.youtube-nocookie.com/embed/W99sFcrdwmE 3117 2026-07-18T14:45:12.000Z 2026-10-22T23:29:54.491Z https://longevityharbor.com/de/watch/W99sFcrdwmE SGLT2-Hemmer, Seneszenz und Telomere: ein Überblick zur Videobeschreibung https://i.ytimg.com/vi/W99sFcrdwmE/hqdefault.jpg Laut Beschreibung könnten SGLT2-Hemmer, entwickelt zur Blutzuckersenkung bei Typ-2-Diabetes, Merkmale des Alterns beeinflussen; genannt werden eine Mausstudie von 2024 zur Beseitigung seneszenter Zellen und eine Humanstudie von 2025 zur Telomerverlängerung. https://www.youtube-nocookie.com/embed/W99sFcrdwmE 3117 2026-07-18T14:45:12.000Z 2026-10-22T23:29:54.491Z https://longevityharbor.com/en/watch/WBhBPxyE374 Dr. Tony Youn: The Anti-Aging Diet and What to Eat for Youthful Skin https://i.ytimg.com/vi/WBhBPxyE374/hqdefault.jpg Want youthful, glowing skin? It all starts with what you eat! From protein and fasting to antioxidants and skincare, we break down the best ways to slow aging and boost collagen naturally. Don’t miss this! Subscribe to Patreon for exclusive weekly content: patreon.com/ArielleLorre Looking for exclusive wellness tips, beauty hacks, and lifestyle insights you won’t find anywhere else? Subscribe to my weekly newsletter for all the inside scoop, including personal routines and healthy living tips! Don’t miss out! https://ariellelorre.com/subscribe/ Follow me: Instagram: https://www.instagram.com/well.pod/?hl=en Facebook: https://www.facebook.com/ariellelorre/ TikTok: https://www.tiktok.com/@ariellelorre?lang=en Pinterest: https://ph.pinterest.com/ariellelorre/ X: https://x.com/ariellelorre YouTube: https://www.youtube.com/@WellwithArielleLorre?sub_confirmation=1 Apple: https://podcasts.apple.com/us/podcast/well-with-arielle-lorre/id1458992375 Spotify: https://open.spotify.com/show/0vrgqp61FJYzGXJnfdv64m #antiaging #skincaresecrets #nutritiontips https://www.youtube-nocookie.com/embed/WBhBPxyE374 770 2025-03-03T14:00:36.000Z 2026-10-22T18:43:11.693Z https://longevityharbor.com/de/watch/WBhBPxyE374 Dr. Tony Youn: The Anti-Aging Diet and What to Eat for Youthful Skin https://i.ytimg.com/vi/WBhBPxyE374/hqdefault.jpg Want youthful, glowing skin? It all starts with what you eat! From protein and fasting to antioxidants and skincare, we break down the best ways to slow aging and boost collagen naturally. Don’t miss this! Subscribe to Patreon for exclusive weekly content: patreon.com/ArielleLorre Looking for exclusive wellness tips, beauty hacks, and lifestyle insights you won’t find anywhere else? Subscribe to my weekly newsletter for all the inside scoop, including personal routines and healthy living tips! Don’t miss out! https://ariellelorre.com/subscribe/ Follow me: Instagram: https://www.instagram.com/well.pod/?hl=en Facebook: https://www.facebook.com/ariellelorre/ TikTok: https://www.tiktok.com/@ariellelorre?lang=en Pinterest: https://ph.pinterest.com/ariellelorre/ X: https://x.com/ariellelorre YouTube: https://www.youtube.com/@WellwithArielleLorre?sub_confirmation=1 Apple: https://podcasts.apple.com/us/podcast/well-with-arielle-lorre/id1458992375 Spotify: https://open.spotify.com/show/0vrgqp61FJYzGXJnfdv64m #antiaging #skincaresecrets #nutritiontips https://www.youtube-nocookie.com/embed/WBhBPxyE374 770 2025-03-03T14:00:36.000Z 2026-10-22T18:43:11.693Z https://longevityharbor.com/en/watch/WFcYF_pxLgA How to Exercise & Eat for Optimal Health & Longevity | Dr. Gabrielle Lyon https://i.ytimg.com/vi/WFcYF_pxLgA/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this episode, my guest is Dr. Gabrielle Lyon, D.O., a board-certified physician who did her clinical and research training at Washington University in geriatrics and nutrition. She is also an expert in how diet and exercise impact muscle and whole-body health and longevity. Dr. Lyon is a bestselling author and public educator. We discuss how healthy skeletal muscle promotes longevity, brain health, disease prevention, ideal body composition, and the health of other organs and bodily systems. She makes specific nutritional recommendations for optimal health: what to eat, how much to eat, the timing of meals, the essential need for adequate quality protein (including animal and plant-based options), supplementation, and how our dietary requirements change with age. She explains why specific types of resistance training are essential to build and maintain muscle and overall metabolic health. She also describes how to include resistance training as part of your exercise regimen — regardless of age or sex. She also provides specific mindset tools to encourage sustained adherence to healthy eating and exercise practices. Women and men of all ages will benefit from Dr. Lyon’s practical, evidence-based protocols to improve muscle and whole-body appearance, function, and health. Access the full show notes, including referenced articles, books, people mentioned, and additional resources: https://www.hubermanlab.com/episode/dr-gabrielle-lyon-how-to-exercise-eat-for-optimal-health-longevity Pre-order Andrew's new book, Protocols: https://protocolsbook.com *Thank you to our sponsors* AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman Levels: https://levels.link/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://insidetracker.com/huberman *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.t https://www.youtube-nocookie.com/embed/WFcYF_pxLgA 11017 2024-06-24T12:00:35.000Z 2026-10-22T18:32:08.327Z https://longevityharbor.com/de/watch/WFcYF_pxLgA How to Exercise & Eat for Optimal Health & Longevity | Dr. Gabrielle Lyon https://i.ytimg.com/vi/WFcYF_pxLgA/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this episode, my guest is Dr. Gabrielle Lyon, D.O., a board-certified physician who did her clinical and research training at Washington University in geriatrics and nutrition. She is also an expert in how diet and exercise impact muscle and whole-body health and longevity. Dr. Lyon is a bestselling author and public educator. We discuss how healthy skeletal muscle promotes longevity, brain health, disease prevention, ideal body composition, and the health of other organs and bodily systems. She makes specific nutritional recommendations for optimal health: what to eat, how much to eat, the timing of meals, the essential need for adequate quality protein (including animal and plant-based options), supplementation, and how our dietary requirements change with age. She explains why specific types of resistance training are essential to build and maintain muscle and overall metabolic health. She also describes how to include resistance training as part of your exercise regimen — regardless of age or sex. She also provides specific mindset tools to encourage sustained adherence to healthy eating and exercise practices. Women and men of all ages will benefit from Dr. Lyon’s practical, evidence-based protocols to improve muscle and whole-body appearance, function, and health. Access the full show notes, including referenced articles, books, people mentioned, and additional resources: https://www.hubermanlab.com/episode/dr-gabrielle-lyon-how-to-exercise-eat-for-optimal-health-longevity Pre-order Andrew's new book, Protocols: https://protocolsbook.com *Thank you to our sponsors* AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman Levels: https://levels.link/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://insidetracker.com/huberman *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.t https://www.youtube-nocookie.com/embed/WFcYF_pxLgA 11017 2024-06-24T12:00:35.000Z 2026-10-22T18:32:08.327Z https://longevityharbor.com/en/watch/WGZ7Dbe3JDM Video description: epigenetic clock, perimenopause and 8 weeks of exercise https://i.ytimg.com/vi/WGZ7Dbe3JDM/hqdefault.jpg The description says the video explains the epigenetic clock, why perimenopause is said to speed biological aging at DNA level, and interventions said to reverse it, including 8 weeks of exercise. These are creator claims; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/WGZ7Dbe3JDM 131 2026-05-22T23:06:14.000Z 2026-10-23T00:30:37.426Z https://longevityharbor.com/de/watch/WGZ7Dbe3JDM Videobeschreibung: epigenetische Uhr, Perimenopause und 8 Wochen Sport https://i.ytimg.com/vi/WGZ7Dbe3JDM/hqdefault.jpg Laut Beschreibung erklärt das Video die epigenetische Uhr, warum die Perimenopause die biologische Alterung auf DNA-Ebene beschleunigen soll, und Maßnahmen, die sie umkehren sollen, darunter 8 Wochen Sport. Das sind Aussagen des Erstellers; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/WGZ7Dbe3JDM 131 2026-05-22T23:06:14.000Z 2026-10-23T00:30:37.426Z https://longevityharbor.com/en/watch/WI2Le8MGHPA Video description: biological vs calendar age and longevity https://i.ytimg.com/vi/WI2Le8MGHPA/hqdefault.jpg The description says biological age does not always match calendar age and names DNA, metabolism, lifestyle, diet and cell health as influences on aging; it does not report study results. https://www.youtube-nocookie.com/embed/WI2Le8MGHPA 746 2026-09-30T13:15:34.000Z 2026-10-22T21:38:30.037Z https://longevityharbor.com/de/watch/WI2Le8MGHPA Videobeschreibung: biologisches vs. Kalenderalter und Longevity https://i.ytimg.com/vi/WI2Le8MGHPA/hqdefault.jpg Die Beschreibung sagt, biologisches Alter entspreche nicht immer dem Kalenderalter, und nennt DNA, Stoffwechsel, Lebensstil, Ernährung und Zellgesundheit als Einflüsse aufs Altern; Studienergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/WI2Le8MGHPA 746 2026-09-30T13:15:34.000Z 2026-10-22T21:38:30.037Z https://longevityharbor.com/en/watch/WNKRSiSGvGE 171- Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules https://i.ytimg.com/vi/WNKRSiSGvGE/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Steve Austad is a distinguished professor of biology at the University of Alabama and director of one of the Nathan Shock Centers of Excellence in aging biology. Steve's current research seeks to understand the underlying causes of aging, specifically with a long-term goal of developing medical interventions that slow the age-related decay of human health. In this episode, Steve tells Peter about his unusual childhood and stints as a cab driver and lion tamer. He goes on to describe what led to his focus on studying aging and some of the major challenges and limitations of working with laboratory animals. Steve and Peter talk about the relationship between caloric restriction and lifespan, including some of the most important studies exploring this question. Additionally, they hypothesize what might explain the sex-related differences in longevity between men and women, explain the importance of finding longevity biomarkers, and discuss the most promising molecules as potential longevity agents. We discuss: 00:00:00 - Intro 00:00:10 - Steve’s background and unusual childhood 00:07:19 - Steve’s adventures driving a cab in New York City 00:12:11 - How Steve drove to LA and accidentally became a lion tamer 00:22:18 - How Steve’s early graduate school experiences led him to study longevity 00:30:35 - The challenges and limitations of working with lab mice 00:43:49 - The connection between caloric restriction and lifespan 00:52:30 - Mice vs. rats and rodent aging experiments 00:57:32 - The impact of dietary composition and the harm of sucrose: Comparing two caloric-restriction studies in monkeys 01:12:22 - Challenges of studying animals due to major differences in the lab animal vs. wild animals 01:28:22 - Human studies of calorie restriction 01:37:18 - Better dietary protocols for humans: Alternatives to long-term caloric restriction 01:42:12 - The protective effect of fasting 01:50:53 - Reflecting on the sex differences in human lifespan, and why https://www.youtube-nocookie.com/embed/WNKRSiSGvGE 9299 2021-08-09T09:45:01.000Z 2026-10-22T17:43:38.473Z https://longevityharbor.com/de/watch/WNKRSiSGvGE 171- Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules https://i.ytimg.com/vi/WNKRSiSGvGE/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Steve Austad is a distinguished professor of biology at the University of Alabama and director of one of the Nathan Shock Centers of Excellence in aging biology. Steve's current research seeks to understand the underlying causes of aging, specifically with a long-term goal of developing medical interventions that slow the age-related decay of human health. In this episode, Steve tells Peter about his unusual childhood and stints as a cab driver and lion tamer. He goes on to describe what led to his focus on studying aging and some of the major challenges and limitations of working with laboratory animals. Steve and Peter talk about the relationship between caloric restriction and lifespan, including some of the most important studies exploring this question. Additionally, they hypothesize what might explain the sex-related differences in longevity between men and women, explain the importance of finding longevity biomarkers, and discuss the most promising molecules as potential longevity agents. We discuss: 00:00:00 - Intro 00:00:10 - Steve’s background and unusual childhood 00:07:19 - Steve’s adventures driving a cab in New York City 00:12:11 - How Steve drove to LA and accidentally became a lion tamer 00:22:18 - How Steve’s early graduate school experiences led him to study longevity 00:30:35 - The challenges and limitations of working with lab mice 00:43:49 - The connection between caloric restriction and lifespan 00:52:30 - Mice vs. rats and rodent aging experiments 00:57:32 - The impact of dietary composition and the harm of sucrose: Comparing two caloric-restriction studies in monkeys 01:12:22 - Challenges of studying animals due to major differences in the lab animal vs. wild animals 01:28:22 - Human studies of calorie restriction 01:37:18 - Better dietary protocols for humans: Alternatives to long-term caloric restriction 01:42:12 - The protective effect of fasting 01:50:53 - Reflecting on the sex differences in human lifespan, and why https://www.youtube-nocookie.com/embed/WNKRSiSGvGE 9299 2021-08-09T09:45:01.000Z 2026-10-22T17:43:38.473Z https://longevityharbor.com/en/watch/WQJcvJDshA8 The Rise of Geroscience: Treating Aging at the Root https://i.ytimg.com/vi/WQJcvJDshA8/hqdefault.jpg #Geroscience #Senolytics https://www.youtube-nocookie.com/embed/WQJcvJDshA8 110 2026-08-16T18:30:25.000Z 2026-10-22T19:04:38.763Z https://longevityharbor.com/de/watch/WQJcvJDshA8 The Rise of Geroscience: Treating Aging at the Root https://i.ytimg.com/vi/WQJcvJDshA8/hqdefault.jpg #Geroscience #Senolytics https://www.youtube-nocookie.com/embed/WQJcvJDshA8 110 2026-08-16T18:30:25.000Z 2026-10-22T19:04:38.763Z https://longevityharbor.com/en/watch/WQY3J0oP0Yo 6 Golden Habits for Healthy Aging - Discover Them Now! https://i.ytimg.com/vi/WQY3J0oP0Yo/hqdefault.jpg 6 Golden Habits for Healthy Aging - Discover Them Now! What separates an 80-year-old living strong and independently from someone at 75 struggling with daily tasks? It isn't genetics or expensive supplements—it comes down to 6 daily, research-backed habits. In this video, 6 Golden Habits for Healthy Aging - Discover Them Now!, Mr. Carl reveals practical lifestyle choices from Harvard, JAMA, and The Lancet to protect your brain, joints, heart, and mobility as you age. No extreme gym workouts. No restrictive diets. Just simple, life-changing habits you can start right now to age on your own terms. ⏱️ TIMESTAMPS & CHAPTERS 00:00 - The Choice: How Do You Want to Live at 80? 01:06 - The 2 Overlooked Habits Your Doctor Rarely Has Time to Discuss 02:36 - Habit 1: Move Every Single Day (The Harvard Step Study & Why 10,000 Steps Is a Myth) 05:18 - Habit 2: Build Strength & Balance (CDC Fall Prevention: Sit-to-Stands & Counter Drills) 07:45 - Habit 3: Protect Relationships Like Your Heart (Social Ties & Cutting Dementia Risk by 50%) 10:11 - Habit 4: Prioritize Restorative Sleep (How Your Brain Flushes Harmful Proteins at Night) 12:45 - Habit 5: Eat a Colorful, Anti-Inflammatory Plate (The PREDIMED Study & Heart Health) 15:05 - Habit 6: Challenge Your Mind Constantly (Neuroplasticity & Building Cognitive Reserve) 17:11 - Your Daily Longevity Action Plan: Start Small Today 🔬 SCIENCE-BACKED TAKEAWAYS IN THIS EPISODE: • Harvard Steps Study (JAMA 2019): Why walking just 4,400 steps a day reduces early mortality risk by 41% compared to 2,700—consistency always beats intensity. • Muscles Are Your Independence Account: How spending 2 minutes doing kitchen-counter balance exercises and chair sit-to-stands protects against fall-related injuries. • The Brain's Night Cleaning Cycle: Landmark research on how deep sleep activates the glymphatic system to wash away amyloid waste. • "Add Before You Subtract": Why focusing on adding colorful plants, olive oil, and fiber dramatically reduces cardiovascular risk without restrictive dieti https://www.youtube-nocookie.com/embed/WQY3J0oP0Yo 1134 2026-10-10T13:30:30.000Z 2026-10-22T18:54:05.946Z https://longevityharbor.com/de/watch/WQY3J0oP0Yo 6 Golden Habits for Healthy Aging - Discover Them Now! https://i.ytimg.com/vi/WQY3J0oP0Yo/hqdefault.jpg 6 Golden Habits for Healthy Aging - Discover Them Now! What separates an 80-year-old living strong and independently from someone at 75 struggling with daily tasks? It isn't genetics or expensive supplements—it comes down to 6 daily, research-backed habits. In this video, 6 Golden Habits for Healthy Aging - Discover Them Now!, Mr. Carl reveals practical lifestyle choices from Harvard, JAMA, and The Lancet to protect your brain, joints, heart, and mobility as you age. No extreme gym workouts. No restrictive diets. Just simple, life-changing habits you can start right now to age on your own terms. ⏱️ TIMESTAMPS & CHAPTERS 00:00 - The Choice: How Do You Want to Live at 80? 01:06 - The 2 Overlooked Habits Your Doctor Rarely Has Time to Discuss 02:36 - Habit 1: Move Every Single Day (The Harvard Step Study & Why 10,000 Steps Is a Myth) 05:18 - Habit 2: Build Strength & Balance (CDC Fall Prevention: Sit-to-Stands & Counter Drills) 07:45 - Habit 3: Protect Relationships Like Your Heart (Social Ties & Cutting Dementia Risk by 50%) 10:11 - Habit 4: Prioritize Restorative Sleep (How Your Brain Flushes Harmful Proteins at Night) 12:45 - Habit 5: Eat a Colorful, Anti-Inflammatory Plate (The PREDIMED Study & Heart Health) 15:05 - Habit 6: Challenge Your Mind Constantly (Neuroplasticity & Building Cognitive Reserve) 17:11 - Your Daily Longevity Action Plan: Start Small Today 🔬 SCIENCE-BACKED TAKEAWAYS IN THIS EPISODE: • Harvard Steps Study (JAMA 2019): Why walking just 4,400 steps a day reduces early mortality risk by 41% compared to 2,700—consistency always beats intensity. • Muscles Are Your Independence Account: How spending 2 minutes doing kitchen-counter balance exercises and chair sit-to-stands protects against fall-related injuries. • The Brain's Night Cleaning Cycle: Landmark research on how deep sleep activates the glymphatic system to wash away amyloid waste. • "Add Before You Subtract": Why focusing on adding colorful plants, olive oil, and fiber dramatically reduces cardiovascular risk without restrictive dieti https://www.youtube-nocookie.com/embed/WQY3J0oP0Yo 1134 2026-10-10T13:30:30.000Z 2026-10-22T18:54:05.946Z https://longevityharbor.com/en/watch/WRwiCWNutAY Dosierter Hunger – Fasten als neues Heilmittel? (2016) https://i.ytimg.com/vi/WRwiCWNutAY/hqdefault.jpg Fasten ist eine machtvolle Waffe gegen Alter und Krankheit. Was Naturvölker und Religionen seit Jahrtausenden machen, wird jetzt auch wissenschaftlich überprüft. Die Erkenntnisse sind verblüffend: Unser Körper hat die Fähigkeit, sich selbst zu reparieren und zu verjüngen. Allerdings nur, wenn er nichts zu essen bekommt. Erste Humanstudien geben Aufschluss über die Fähigkeiten unseres Selbstheilungsprogramms, das bis hin zur Bekämpfung von Krebs gehen könnte. Doch welche Art zu fasten ist die richtige? Und gibt es den Fasteneffekt irgendwann vielleicht sogar in Pillenform? Ein NZZ Format über den Hunger und seine essentiellen Auswirkungen. ► Abonnieren Sie unseren YouTube-Kanal und aktivieren Sie die Glocke, um kein Video zu verpassen: https://goo.gl/Fy28as ► NZZ Format: Dok-Filme der Neuen Zürcher Zeitung: jeden Donnerstag um 23 Uhr auf SRF1. https://www.youtube-nocookie.com/embed/WRwiCWNutAY 1753 2024-06-30T15:00:34.000Z 2026-10-22T18:32:09.024Z https://longevityharbor.com/de/watch/WRwiCWNutAY Dosierter Hunger – Fasten als neues Heilmittel? (2016) https://i.ytimg.com/vi/WRwiCWNutAY/hqdefault.jpg Fasten ist eine machtvolle Waffe gegen Alter und Krankheit. Was Naturvölker und Religionen seit Jahrtausenden machen, wird jetzt auch wissenschaftlich überprüft. Die Erkenntnisse sind verblüffend: Unser Körper hat die Fähigkeit, sich selbst zu reparieren und zu verjüngen. Allerdings nur, wenn er nichts zu essen bekommt. Erste Humanstudien geben Aufschluss über die Fähigkeiten unseres Selbstheilungsprogramms, das bis hin zur Bekämpfung von Krebs gehen könnte. Doch welche Art zu fasten ist die richtige? Und gibt es den Fasteneffekt irgendwann vielleicht sogar in Pillenform? Ein NZZ Format über den Hunger und seine essentiellen Auswirkungen. ► Abonnieren Sie unseren YouTube-Kanal und aktivieren Sie die Glocke, um kein Video zu verpassen: https://goo.gl/Fy28as ► NZZ Format: Dok-Filme der Neuen Zürcher Zeitung: jeden Donnerstag um 23 Uhr auf SRF1. https://www.youtube-nocookie.com/embed/WRwiCWNutAY 1753 2024-06-30T15:00:34.000Z 2026-10-22T18:32:09.024Z https://longevityharbor.com/en/watch/WXwLl8dWCpA Video description: GlyNAC trial in older adults and mouse lifespan data https://i.ytimg.com/vi/WXwLl8dWCpA/hqdefault.jpg The description presents a 16-week Baylor double-blind randomized trial of GlyNAC (glycine plus N-acetylcysteine) in older adults, reporting improved glutathione, mitochondrial fat oxidation and physical function, while lean muscle mass did not increase. https://www.youtube-nocookie.com/embed/WXwLl8dWCpA 875 2026-09-22T16:00:22.000Z 2026-10-22T21:57:53.947Z https://longevityharbor.com/de/watch/WXwLl8dWCpA Videobeschreibung: GlyNAC-Studie bei älteren Erwachsenen und Maus-Lebensdauer https://i.ytimg.com/vi/WXwLl8dWCpA/hqdefault.jpg Die Beschreibung stellt eine 16-wöchige doppelblinde randomisierte Baylor-Studie zu GlyNAC (Glycin plus N-Acetylcystein) bei älteren Erwachsenen vor: verbesserte Glutathionwerte, mitochondriale Fettoxidation und körperliche Funktion, während die fettfreie Muskelmasse nicht zunahm. https://www.youtube-nocookie.com/embed/WXwLl8dWCpA 875 2026-09-22T16:00:22.000Z 2026-10-22T21:57:53.947Z https://longevityharbor.com/en/watch/WY5QQ-QjlFc Calorie Diets Could Extend Life Span And Delay Disease, Researchers Say | NBC Nightly News https://i.ytimg.com/vi/WY5QQ-QjlFc/hqdefault.jpg Calorie restriction diets, which in some cases involve eating 50 percent fewer calories than the recommended amount for active men and women, could be the secret to living longer and healthier, researchers say. New studies are building a case for the diet’s benefits, but medical experts haven’t reached a consensus. https://www.youtube-nocookie.com/embed/WY5QQ-QjlFc 163 2018-11-26T00:18:43.000Z 2026-10-22T17:43:38.441Z https://longevityharbor.com/de/watch/WY5QQ-QjlFc Calorie Diets Could Extend Life Span And Delay Disease, Researchers Say | NBC Nightly News https://i.ytimg.com/vi/WY5QQ-QjlFc/hqdefault.jpg Calorie restriction diets, which in some cases involve eating 50 percent fewer calories than the recommended amount for active men and women, could be the secret to living longer and healthier, researchers say. New studies are building a case for the diet’s benefits, but medical experts haven’t reached a consensus. https://www.youtube-nocookie.com/embed/WY5QQ-QjlFc 163 2018-11-26T00:18:43.000Z 2026-10-22T17:43:38.441Z https://longevityharbor.com/en/watch/W_9haDhnDks Weight Loss Sustainability IF vs CR https://i.ytimg.com/vi/W_9haDhnDks/hqdefault.jpg Any scientific evidence showing potential benefits of a treatment in scientific studies must ultimately be demonstrated in the practical arena. This is accomplished by Randomized Clinical Trials to assure the medical validity of a treatment or intervention. Regardless of what multiple studies, let alone anecdotal evidence, show, such trials are essential. The value of caloric restriction for 1) longevity and 2) obesity prevention has long been held. However, to meet these two goals caloric restriction must be sustainable for the long term. That is not practical for most humans. Furthermore, caloric restriction may cause lowering of the basic metabolic rate. Ultimately, caloric restriction will become more and more difficult for the patient.(see previous video) Intermittent Fasting, does not necessarily involve caloric restriction. Fasting may in fact increase the basic metabolic rate (check my previous video about it). Additionally, fasting shows long-term sustainability (or adherence). Sustainability makes Intermittent Fasting a viable alternative to caloric restriction. This systematic review paper just published in the scientific journal “Nutrients” looked at 30 Clinical trials of Intermittent fasting or Caloric Restriction or both. The authors concluded that Both IF and CR protocols show promise in improving the following: weight loss, blood lipids, glucose metabolism, insulin sensitivity and reduction of oxidative stress and inflammation. Therefore, both have potential geroprotective effects on cardiometabolic, cancer, and neurocognitive outcomes. Adherence to long-term CR however, was reportedly low. This indicates that it may not be sustainable for most individuals over extended periods. On the other hand, IF interventions demonstrated increased adherence and long-term sustainability, As more and more clinical trials are published, the multiple benefits and practical application of IF will become clearer. However, a IF lifestyle is sustainable for prolonged periods. I should know, I have been in OMAD https://www.youtube-nocookie.com/embed/W_9haDhnDks 222 2024-04-08T07:28:02.000Z 2026-10-22T18:32:09.992Z https://longevityharbor.com/de/watch/W_9haDhnDks Weight Loss Sustainability IF vs CR https://i.ytimg.com/vi/W_9haDhnDks/hqdefault.jpg Any scientific evidence showing potential benefits of a treatment in scientific studies must ultimately be demonstrated in the practical arena. This is accomplished by Randomized Clinical Trials to assure the medical validity of a treatment or intervention. Regardless of what multiple studies, let alone anecdotal evidence, show, such trials are essential. The value of caloric restriction for 1) longevity and 2) obesity prevention has long been held. However, to meet these two goals caloric restriction must be sustainable for the long term. That is not practical for most humans. Furthermore, caloric restriction may cause lowering of the basic metabolic rate. Ultimately, caloric restriction will become more and more difficult for the patient.(see previous video) Intermittent Fasting, does not necessarily involve caloric restriction. Fasting may in fact increase the basic metabolic rate (check my previous video about it). Additionally, fasting shows long-term sustainability (or adherence). Sustainability makes Intermittent Fasting a viable alternative to caloric restriction. This systematic review paper just published in the scientific journal “Nutrients” looked at 30 Clinical trials of Intermittent fasting or Caloric Restriction or both. The authors concluded that Both IF and CR protocols show promise in improving the following: weight loss, blood lipids, glucose metabolism, insulin sensitivity and reduction of oxidative stress and inflammation. Therefore, both have potential geroprotective effects on cardiometabolic, cancer, and neurocognitive outcomes. Adherence to long-term CR however, was reportedly low. This indicates that it may not be sustainable for most individuals over extended periods. On the other hand, IF interventions demonstrated increased adherence and long-term sustainability, As more and more clinical trials are published, the multiple benefits and practical application of IF will become clearer. However, a IF lifestyle is sustainable for prolonged periods. I should know, I have been in OMAD https://www.youtube-nocookie.com/embed/W_9haDhnDks 222 2024-04-08T07:28:02.000Z 2026-10-22T18:32:09.992Z https://longevityharbor.com/en/watch/WaHT4Wm5430 Video description: alcohol, DNA methylation and epigenetic aging markers https://i.ytimg.com/vi/WaHT4Wm5430/hqdefault.jpg The description says the episode explores how alcohol affects DNA methylation patterns, oxidative stress pathways and mitochondrial function, and how these molecular changes may accelerate epigenetic aging markers inside cells. It links this to long-term health risks of chronic consumption. https://www.youtube-nocookie.com/embed/WaHT4Wm5430 364 2026-03-07T19:25:01.000Z 2026-10-23T02:12:03.547Z https://longevityharbor.com/de/watch/WaHT4Wm5430 Videobeschreibung: Alkohol, DNA-Methylierung und epigenetische Alternsmarker https://i.ytimg.com/vi/WaHT4Wm5430/hqdefault.jpg Laut Beschreibung untersucht die Episode, wie Alkohol DNA-Methylierungsmuster, oxidative Stresswege und die Mitochondrienfunktion beeinflusst und wie diese molekularen Veränderungen epigenetische Alternsmarker in Zellen beschleunigen könnten. Sie verknüpft dies mit langfristigen Gesundheitsrisiken chronischen Konsums. https://www.youtube-nocookie.com/embed/WaHT4Wm5430 364 2026-03-07T19:25:01.000Z 2026-10-23T02:12:03.547Z https://longevityharbor.com/en/watch/WcwCKM8yMec The Science of Intermittent Fasting https://i.ytimg.com/vi/WcwCKM8yMec/hqdefault.jpg How does intermittent fasting relate to longevity? Intermittent fasting is not just a fad diet, it may be a critical component of living a long, extended healthy life. There are many different types of intermittent fasting including alternate day fasting, time restricted feeding and a 5:2 method for fasting. No matter what type of fasting you choose...the important question is "how does intermittent fasting effect longevity and aging?" If there is one specific truth in whatever behavior you do with respect to longevity...it's consistency! TAKE A DEEPER DIVE INTO AGING AND LONGEVITY Lifespan by Dr. David Sinclair - https://citizensurgeon.co/Lifespan Bluezones by Dan Buettner - https://citizensurgeon.co/Bluezones Outlive by Peter Attia - https://citizensurgeon.co/Outlive Ending Aging by Aubrey Degrey - https://citizensurgeon.co/EndingAging In this video I'm going to take you through the different types of intermittent fasting. I'm going to explore the science and show you the cellular effects of intermittent fasting. We're going to dive into mTOR and a few different pathways that will help give you the WHY so you can remember. If you want to sign up for the CITIZENSURGEON community sign up right here!! https://citizensurgeon.co/signup Finally I'm going to demonstrate the type of fasting that is the most effective and the type that is the most sustainable. Jump ahead with these chapter links! Start 00:00 Types of Intermittent Fasting 01:00 What is autophagy? 03:33 mTOR and Longevity explained 05:15 Hormesis, the Sweet Spot and Longevity 09:42 Most effective types of Intermittent Fasting 14:44 Caution with Intermittent Fasting 17:08 My Fasting Routine 19:04 WHO AM I? I'm Dr. Erik Pearson, FACS and I am a board certified pediatric surgeon living in Las Vegas. I make surgical education videos on all topics in general surgery, health, longevity as well as talks on lifestyle design as a surgeon, book reviews, and studying effectively. I also write a substack exploring the depths of life as a sur https://www.youtube-nocookie.com/embed/WcwCKM8yMec 1308 2024-11-25T14:28:30.000Z 2026-10-22T18:32:09.941Z https://longevityharbor.com/de/watch/WcwCKM8yMec The Science of Intermittent Fasting https://i.ytimg.com/vi/WcwCKM8yMec/hqdefault.jpg How does intermittent fasting relate to longevity? Intermittent fasting is not just a fad diet, it may be a critical component of living a long, extended healthy life. There are many different types of intermittent fasting including alternate day fasting, time restricted feeding and a 5:2 method for fasting. No matter what type of fasting you choose...the important question is "how does intermittent fasting effect longevity and aging?" If there is one specific truth in whatever behavior you do with respect to longevity...it's consistency! TAKE A DEEPER DIVE INTO AGING AND LONGEVITY Lifespan by Dr. David Sinclair - https://citizensurgeon.co/Lifespan Bluezones by Dan Buettner - https://citizensurgeon.co/Bluezones Outlive by Peter Attia - https://citizensurgeon.co/Outlive Ending Aging by Aubrey Degrey - https://citizensurgeon.co/EndingAging In this video I'm going to take you through the different types of intermittent fasting. I'm going to explore the science and show you the cellular effects of intermittent fasting. We're going to dive into mTOR and a few different pathways that will help give you the WHY so you can remember. If you want to sign up for the CITIZENSURGEON community sign up right here!! https://citizensurgeon.co/signup Finally I'm going to demonstrate the type of fasting that is the most effective and the type that is the most sustainable. Jump ahead with these chapter links! Start 00:00 Types of Intermittent Fasting 01:00 What is autophagy? 03:33 mTOR and Longevity explained 05:15 Hormesis, the Sweet Spot and Longevity 09:42 Most effective types of Intermittent Fasting 14:44 Caution with Intermittent Fasting 17:08 My Fasting Routine 19:04 WHO AM I? I'm Dr. Erik Pearson, FACS and I am a board certified pediatric surgeon living in Las Vegas. I make surgical education videos on all topics in general surgery, health, longevity as well as talks on lifestyle design as a surgeon, book reviews, and studying effectively. I also write a substack exploring the depths of life as a sur https://www.youtube-nocookie.com/embed/WcwCKM8yMec 1308 2024-11-25T14:28:30.000Z 2026-10-22T18:32:09.941Z https://longevityharbor.com/en/watch/WjGnNpwB4B4 Getting Stiffer With Age? It's Not What You Think https://i.ytimg.com/vi/WjGnNpwB4B4/hqdefault.jpg Can scientists reverse age-related stiffness and cellular aging? New 2025 research reveals how the extracellular matrix, collagen aging, tissue stiffness, and mechanical forces influence aging cells—and why these discoveries don't yet mean scientists can reverse aging in humans. In this episode of Health Sense or Nonsense, Marcus, a research scientist with over 25 years of experience, investigates two fascinating 2025 studies published in Aging Cell and Nature Materials. Discover how mechanotransduction, epigenetic changes, and the environment surrounding our cells may influence cellular aging. We'll separate promising anti-aging research from exaggerated claims about reversing joint stiffness, restoring collagen, and rejuvenating human tissue. 🔬 What's Covered in This Video • Why tissues change with age: How collagen cross-linking, elastin deterioration, and extracellular matrix remodeling affect tissue mechanics. • Can mechanical forces rejuvenate cells? What a 2025 Aging Cell study found when researchers compressed aged human dermal fibroblasts and observed epigenetic and functional changes. • Does softer tissue mean younger cells? How a 2025 Nature Materials study separated stiffness from extracellular matrix signals using young and aged mouse heart tissue. • Health Sense or Nonsense? Why these discoveries don't prove that massage, compression devices, collagen supplements, or other products reverse human aging or joint stiffness. ⏱️ Chapters 00:00 Why Stiffness Changes 01:54 Cells and Matrix Link 03:36 Three Types of Stiff 04:41 Medical Disclaimer 05:32 Compression Study Explained 06:34 What Rejuvenation Means 07:48 Mouse Heart Matrix Clue 09:00 Takeaways and Wrap Up 09:56 Health Sense Verdict 10:38 Next Video Teaser 📚 Scientific Sources 1. Journal: Aging Cell (2025) Article Title: Compressive Forces Induce Epigenetic Activation of Aged Human Dermal Fibroblasts Through ERK Signaling Pathway Link: https://onlinelibrary.wiley.com/doi/10.1111/acel.70035 2. Journal: Nature Materials (2025) Article Title: Hy https://www.youtube-nocookie.com/embed/WjGnNpwB4B4 665 2026-10-17T16:00:35.000Z 2026-10-22T19:54:19.316Z https://longevityharbor.com/de/watch/WjGnNpwB4B4 Getting Stiffer With Age? It's Not What You Think https://i.ytimg.com/vi/WjGnNpwB4B4/hqdefault.jpg Can scientists reverse age-related stiffness and cellular aging? New 2025 research reveals how the extracellular matrix, collagen aging, tissue stiffness, and mechanical forces influence aging cells—and why these discoveries don't yet mean scientists can reverse aging in humans. In this episode of Health Sense or Nonsense, Marcus, a research scientist with over 25 years of experience, investigates two fascinating 2025 studies published in Aging Cell and Nature Materials. Discover how mechanotransduction, epigenetic changes, and the environment surrounding our cells may influence cellular aging. We'll separate promising anti-aging research from exaggerated claims about reversing joint stiffness, restoring collagen, and rejuvenating human tissue. 🔬 What's Covered in This Video • Why tissues change with age: How collagen cross-linking, elastin deterioration, and extracellular matrix remodeling affect tissue mechanics. • Can mechanical forces rejuvenate cells? What a 2025 Aging Cell study found when researchers compressed aged human dermal fibroblasts and observed epigenetic and functional changes. • Does softer tissue mean younger cells? How a 2025 Nature Materials study separated stiffness from extracellular matrix signals using young and aged mouse heart tissue. • Health Sense or Nonsense? Why these discoveries don't prove that massage, compression devices, collagen supplements, or other products reverse human aging or joint stiffness. ⏱️ Chapters 00:00 Why Stiffness Changes 01:54 Cells and Matrix Link 03:36 Three Types of Stiff 04:41 Medical Disclaimer 05:32 Compression Study Explained 06:34 What Rejuvenation Means 07:48 Mouse Heart Matrix Clue 09:00 Takeaways and Wrap Up 09:56 Health Sense Verdict 10:38 Next Video Teaser 📚 Scientific Sources 1. Journal: Aging Cell (2025) Article Title: Compressive Forces Induce Epigenetic Activation of Aged Human Dermal Fibroblasts Through ERK Signaling Pathway Link: https://onlinelibrary.wiley.com/doi/10.1111/acel.70035 2. Journal: Nature Materials (2025) Article Title: Hy https://www.youtube-nocookie.com/embed/WjGnNpwB4B4 665 2026-10-17T16:00:35.000Z 2026-10-22T19:54:19.316Z https://longevityharbor.com/en/watch/Wok2yH9JLAk Surgeon REVEALS: 5 Science-Backed Exercises that REVERSE Aging! | Senior Health. https://i.ytimg.com/vi/Wok2yH9JLAk/hqdefault.jpg Can we actually turn back the biological clock? 🕰️ The answer is a resounding YES! Welcome back to the channel! 👨‍⚕️ In today’s deep dive, a board-certified surgeon breaks down the latest medical breakthroughs in longevity science. We aren't just talking about "staying active"—we are looking at the 5 Science-Backed Exercises that target your cells, mitochondria, and DNA to literally REVERSE the aging process. 🧬✨ As we age, our bodies face challenges like sarcopenia (muscle loss), bone density reduction, and cognitive decline. However, recent clinical studies in 2025 have proven that specific movement patterns can trigger cellular autophagy and increase telomere length. 🧬📈 In this video, you will discover the exact "Longevity Protocol" used by top health experts to maintain peak physical and mental performance well into your 70s, 80s, and beyond! 🚀 What you will learn in this ultimate Senior Health Guide: ✅ The #1 exercise that boosts mitochondrial health by 69% 🔋 ✅ How to protect your joints while building functional strength 🦴 ✅ The "Brain-Body" connection: Exercises that prevent memory loss 🧠 ✅ A surgeon's secret to maintaining posture and balance to prevent falls ⚖️ ✅ Scientific breakdown of why these 5 movements "de-age" your heart and lungs 🫀 Stop guessing and start following a routine backed by hard science. Whether you are 50 or 85, it is never too late to start your rejuvenation journey! 💪🌟 Our mission is to provide life-saving medical information and health strategies directly from a surgical perspective. We focus on Longevity, Preventative Medicine, and Senior Vitality. We believe that age is just a number and that with the right science, everyone can live a vibrant, pain-free life. Subscribe to join our community of 2025 health warriors! 🏥🔥 💬 JOIN THE CONVERSATION I want to hear from you! Which of these exercises are you going to try first? Do you have any specific health concerns regarding your joints or heart? Drop a comment below—I read as many as I can to help guide my future video https://www.youtube-nocookie.com/embed/Wok2yH9JLAk 2360 2025-12-28T01:30:30.000Z 2026-10-22T18:54:06.005Z https://longevityharbor.com/de/watch/Wok2yH9JLAk Surgeon REVEALS: 5 Science-Backed Exercises that REVERSE Aging! | Senior Health. https://i.ytimg.com/vi/Wok2yH9JLAk/hqdefault.jpg Can we actually turn back the biological clock? 🕰️ The answer is a resounding YES! Welcome back to the channel! 👨‍⚕️ In today’s deep dive, a board-certified surgeon breaks down the latest medical breakthroughs in longevity science. We aren't just talking about "staying active"—we are looking at the 5 Science-Backed Exercises that target your cells, mitochondria, and DNA to literally REVERSE the aging process. 🧬✨ As we age, our bodies face challenges like sarcopenia (muscle loss), bone density reduction, and cognitive decline. However, recent clinical studies in 2025 have proven that specific movement patterns can trigger cellular autophagy and increase telomere length. 🧬📈 In this video, you will discover the exact "Longevity Protocol" used by top health experts to maintain peak physical and mental performance well into your 70s, 80s, and beyond! 🚀 What you will learn in this ultimate Senior Health Guide: ✅ The #1 exercise that boosts mitochondrial health by 69% 🔋 ✅ How to protect your joints while building functional strength 🦴 ✅ The "Brain-Body" connection: Exercises that prevent memory loss 🧠 ✅ A surgeon's secret to maintaining posture and balance to prevent falls ⚖️ ✅ Scientific breakdown of why these 5 movements "de-age" your heart and lungs 🫀 Stop guessing and start following a routine backed by hard science. Whether you are 50 or 85, it is never too late to start your rejuvenation journey! 💪🌟 Our mission is to provide life-saving medical information and health strategies directly from a surgical perspective. We focus on Longevity, Preventative Medicine, and Senior Vitality. We believe that age is just a number and that with the right science, everyone can live a vibrant, pain-free life. Subscribe to join our community of 2025 health warriors! 🏥🔥 💬 JOIN THE CONVERSATION I want to hear from you! Which of these exercises are you going to try first? Do you have any specific health concerns regarding your joints or heart? Drop a comment below—I read as many as I can to help guide my future video https://www.youtube-nocookie.com/embed/Wok2yH9JLAk 2360 2025-12-28T01:30:30.000Z 2026-10-22T18:54:06.005Z https://longevityharbor.com/en/watch/WsnghQxZ7z0 How to Become a “Super Ager:” The Science-Backed Secrets to Longevity | Amanpour and Company https://i.ytimg.com/vi/WsnghQxZ7z0/hqdefault.jpg We're often warned of what to expect with an aging population: the drain on the economy, the workforce, medical services and so much more. Now, Dr. Eric Topol suggests there is reason for hope — in new technology and medications with the potential to extend vibrant good health until later in life. Dr. Topol joins Walter Isaacson to discuss what he calls a "breakthrough moment in the history of human healthcare." Originally aired on July 11, 2025 ---------------------------------------------------------------------------------------------------------------------------------------- Major support for Amanpour and Company is provided by Jim Attwood and Leslie Williams, Candace King Weir, the Sylvia A. and Simon B. Poyta Programming Endowment to Fight Antisemitism, the Leila and Mickey Straus Family Charitable Trust, Mark J. Blechner, the Filomen M. D’Agostino Foundation, Seton J. Melvin, the Peter G. Peterson and Joan Ganz Cooney Fund, Charles Rosenblum, Koo and Patricia Yuen, Barbara Hope Zuckerberg, and Jeffrey Katz and Beth Rogers. Subscribe to the Amanpour and Company channel here: https://bit.ly/2EMIkTJ Subscribe to our daily newsletter to find out who's on each night: http://www.pbs.org/wnet/amanpour-and-company/newsletter/ For more from Amanpour and Company, including full episodes, click here: https://to.pbs.org/2NBFpjf This program is made possible by viewers like you. Please support your local PBS station: http://www.pbs.org/donate Like Amanpour and Company on Facebook: https://bit.ly/2HNx3EF Follow Amanpour and Company on Twitter: https://bit.ly/2HLpjTI Follow Amanpour and Company on Instagram: https://bit.ly/3SaTUhk Watch Amanpour and Company weekdays on PBS (check local listings). Amanpour and Company features wide-ranging, in-depth conversations with global thought leaders and cultural influencers on the issues and trends impacting the world each day, from politics, business and technology to arts, science and sports. Christiane Amanpour leads the conversation on global and domestic news fr https://www.youtube-nocookie.com/embed/WsnghQxZ7z0 1064 2025-07-11T21:50:37.000Z 2026-10-22T18:43:11.801Z https://longevityharbor.com/de/watch/WsnghQxZ7z0 How to Become a “Super Ager:” The Science-Backed Secrets to Longevity | Amanpour and Company https://i.ytimg.com/vi/WsnghQxZ7z0/hqdefault.jpg We're often warned of what to expect with an aging population: the drain on the economy, the workforce, medical services and so much more. Now, Dr. Eric Topol suggests there is reason for hope — in new technology and medications with the potential to extend vibrant good health until later in life. Dr. Topol joins Walter Isaacson to discuss what he calls a "breakthrough moment in the history of human healthcare." Originally aired on July 11, 2025 ---------------------------------------------------------------------------------------------------------------------------------------- Major support for Amanpour and Company is provided by Jim Attwood and Leslie Williams, Candace King Weir, the Sylvia A. and Simon B. Poyta Programming Endowment to Fight Antisemitism, the Leila and Mickey Straus Family Charitable Trust, Mark J. Blechner, the Filomen M. D’Agostino Foundation, Seton J. Melvin, the Peter G. Peterson and Joan Ganz Cooney Fund, Charles Rosenblum, Koo and Patricia Yuen, Barbara Hope Zuckerberg, and Jeffrey Katz and Beth Rogers. Subscribe to the Amanpour and Company channel here: https://bit.ly/2EMIkTJ Subscribe to our daily newsletter to find out who's on each night: http://www.pbs.org/wnet/amanpour-and-company/newsletter/ For more from Amanpour and Company, including full episodes, click here: https://to.pbs.org/2NBFpjf This program is made possible by viewers like you. Please support your local PBS station: http://www.pbs.org/donate Like Amanpour and Company on Facebook: https://bit.ly/2HNx3EF Follow Amanpour and Company on Twitter: https://bit.ly/2HLpjTI Follow Amanpour and Company on Instagram: https://bit.ly/3SaTUhk Watch Amanpour and Company weekdays on PBS (check local listings). Amanpour and Company features wide-ranging, in-depth conversations with global thought leaders and cultural influencers on the issues and trends impacting the world each day, from politics, business and technology to arts, science and sports. Christiane Amanpour leads the conversation on global and domestic news fr https://www.youtube-nocookie.com/embed/WsnghQxZ7z0 1064 2025-07-11T21:50:37.000Z 2026-10-22T18:43:11.801Z https://longevityharbor.com/en/watch/Wwcn_RnNPjM The Longevity "X-Factor" with Intermittent Fasting https://i.ytimg.com/vi/Wwcn_RnNPjM/hqdefault.jpg The Secret YOU NEED to KNOW when Intermittent Fasting and Time Restricted Eating... Sub For Weekly Educational Sarcasm - https://www.youtube.com/channel/UCTFEW_zZHo76X-DQRrouHFA?sub_confirmation=1 🗣💬 What's YOUR Meal Timing Strategy Look Like? 👇COMMENT BELOW!👇 Things I Use - https://liftnbalance.com/kevin-recommends/ Weekly Email - https://liftnbalance.mailchimpsites.com/ TikTok (if you dare) - https://vm.tiktok.com/TNX2Lm/ Referenced Research: https://www.nature.com/articles/s41586-024-08026-3 https://www.nature.com/articles/ncomms14063 Additional Resources/Charts From: https://peterattiamd.com/calorie-restriction-part-iia-monkey-studies/ Chapters: 0:00 Intro 2:18 The X-Factor 7:29 New Data 11:33 Your Strategy ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ SHOW LINKS! My EARLY EATING Strategy - https://youtu.be/4_UEJITpki4 Time Restricted Eating vs. Inflammation - https://youtu.be/pZ7gMM4AL2s Circadian Eatings Magic - https://youtu.be/NBZ_Dq1XJao Enhance Your Cellular Recycling - https://youtu.be/RvktcHRWpgc Fix Your Body Clock - https://youtu.be/V8gSJXX45DE How to SLEEP - https://www.youtube.com/playlist?list=PLjik_dZXdlnbpEFcEU2ZckO942HjFOz6d How to EAT Playlist - https://www.youtube.com/playlist?list=PLjik_dZXdlnYdEp9mIzQoeSTYkMOKalBp LONGEVITY 101 Playlist - https://www.youtube.com/playlist?list=PLjik_dZXdlnbcSWEXTHxFSKg4rT1N9sGB FASTING 101 - https://www.youtube.com/playlist?list=PLjik_dZXdlnb2qXHnBWBoGLdbKuzX9ZvX ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ WHAT ELSE??? Weekly Workouts - https://www.youtube.com/watch?v=JFf8oK0fP0U&list=PLjik_dZXdlnZJag8XwxAdLx60PQZ0x1dF THE BLOG - https://liftnbalance.com/ Instagram - https://www.instagram.com/liftnbalance/ TikTok - https://vm.tiktok.com/TNX2Lm/ Facebook - https://www.facebook.com/LiftNBal/ Twitter - https://twitter.com/LiftnBalance PS - It's a Great Day to Have a Great Day!🤙 🎶- - - - - - - - - - - - - - - - - - - - - - - - - - -🎶 @Vexento 🎶- - - - - - - - - - - - - - - - - - - - - - - - - - -🎶 ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ Disclaimer This is no https://www.youtube-nocookie.com/embed/Wwcn_RnNPjM 920 2024-10-18T12:24:07.000Z 2026-10-22T18:54:08.169Z https://longevityharbor.com/de/watch/Wwcn_RnNPjM The Longevity "X-Factor" with Intermittent Fasting https://i.ytimg.com/vi/Wwcn_RnNPjM/hqdefault.jpg The Secret YOU NEED to KNOW when Intermittent Fasting and Time Restricted Eating... Sub For Weekly Educational Sarcasm - https://www.youtube.com/channel/UCTFEW_zZHo76X-DQRrouHFA?sub_confirmation=1 🗣💬 What's YOUR Meal Timing Strategy Look Like? 👇COMMENT BELOW!👇 Things I Use - https://liftnbalance.com/kevin-recommends/ Weekly Email - https://liftnbalance.mailchimpsites.com/ TikTok (if you dare) - https://vm.tiktok.com/TNX2Lm/ Referenced Research: https://www.nature.com/articles/s41586-024-08026-3 https://www.nature.com/articles/ncomms14063 Additional Resources/Charts From: https://peterattiamd.com/calorie-restriction-part-iia-monkey-studies/ Chapters: 0:00 Intro 2:18 The X-Factor 7:29 New Data 11:33 Your Strategy ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ SHOW LINKS! My EARLY EATING Strategy - https://youtu.be/4_UEJITpki4 Time Restricted Eating vs. Inflammation - https://youtu.be/pZ7gMM4AL2s Circadian Eatings Magic - https://youtu.be/NBZ_Dq1XJao Enhance Your Cellular Recycling - https://youtu.be/RvktcHRWpgc Fix Your Body Clock - https://youtu.be/V8gSJXX45DE How to SLEEP - https://www.youtube.com/playlist?list=PLjik_dZXdlnbpEFcEU2ZckO942HjFOz6d How to EAT Playlist - https://www.youtube.com/playlist?list=PLjik_dZXdlnYdEp9mIzQoeSTYkMOKalBp LONGEVITY 101 Playlist - https://www.youtube.com/playlist?list=PLjik_dZXdlnbcSWEXTHxFSKg4rT1N9sGB FASTING 101 - https://www.youtube.com/playlist?list=PLjik_dZXdlnb2qXHnBWBoGLdbKuzX9ZvX ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ WHAT ELSE??? Weekly Workouts - https://www.youtube.com/watch?v=JFf8oK0fP0U&list=PLjik_dZXdlnZJag8XwxAdLx60PQZ0x1dF THE BLOG - https://liftnbalance.com/ Instagram - https://www.instagram.com/liftnbalance/ TikTok - https://vm.tiktok.com/TNX2Lm/ Facebook - https://www.facebook.com/LiftNBal/ Twitter - https://twitter.com/LiftnBalance PS - It's a Great Day to Have a Great Day!🤙 🎶- - - - - - - - - - - - - - - - - - - - - - - - - - -🎶 @Vexento 🎶- - - - - - - - - - - - - - - - - - - - - - - - - - -🎶 ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ Disclaimer This is no https://www.youtube-nocookie.com/embed/Wwcn_RnNPjM 920 2024-10-18T12:24:07.000Z 2026-10-22T18:54:08.169Z https://longevityharbor.com/en/watch/WzWGvqqgfw4 5 Science-Backed Exercises That Reverse Aging https://i.ytimg.com/vi/WzWGvqqgfw4/hqdefault.jpg 🔗 The plan to help you live longer, stronger, and healthier after 60: https://ehhacks.com/ 5 Science-Backed Exercises That Reverse Aging explores five types of movement that can help older adults improve strength, cardiovascular fitness, balance, energy, and physical function. You cannot literally turn back your chronological age. But exercise can improve many of the biological systems that decline with aging — including VO2 max, muscle strength, mitochondrial function, insulin sensitivity, balance, mobility, and cardiovascular health. In this video, Dr. Hana Sasaki explains the five movement strategies that matter most and how to combine them safely after 60. 5 Science-Backed Exercises That Reverse Aging is not about extreme workouts. It is about giving your body regular signals to stay strong, capable, and metabolically active. THE 5 EXERCISE STRATEGIES: 1. BRISK WALKING & MODERATE AEROBIC EXERCISE Walking at a pace that noticeably increases breathing trains your heart and lungs while improving endurance and everyday mobility. Start with 10 minutes if necessary and gradually work toward longer sessions. 2. INTERVAL TRAINING Alternating easier movement with short periods of higher effort can produce strong improvements in cardiorespiratory fitness. For example: three minutes of brisk walking followed by one minute at a faster pace, repeated several times. Older adults with cardiovascular disease or other significant medical conditions should discuss vigorous intervals with their healthcare professional first. 3. RESISTANCE TRAINING Chair squats, wall push-ups, resistance bands, rows, step-ups, and other progressive exercises can strengthen major muscle groups without requiring heavy gym equipment. WHO recommends muscle-strengthening activity involving all major muscle groups on at least two days per week. 4. STEADY ENDURANCE EXERCISE Longer moderate sessions of walking, swimming, cycling, or hiking help develop cardiovascular endurance and provide another stimulus for mitochondrial and metaboli https://www.youtube-nocookie.com/embed/WzWGvqqgfw4 1081 2026-09-14T17:06:43.000Z 2026-10-22T18:32:08.288Z https://longevityharbor.com/de/watch/WzWGvqqgfw4 5 Science-Backed Exercises That Reverse Aging https://i.ytimg.com/vi/WzWGvqqgfw4/hqdefault.jpg 🔗 The plan to help you live longer, stronger, and healthier after 60: https://ehhacks.com/ 5 Science-Backed Exercises That Reverse Aging explores five types of movement that can help older adults improve strength, cardiovascular fitness, balance, energy, and physical function. You cannot literally turn back your chronological age. But exercise can improve many of the biological systems that decline with aging — including VO2 max, muscle strength, mitochondrial function, insulin sensitivity, balance, mobility, and cardiovascular health. In this video, Dr. Hana Sasaki explains the five movement strategies that matter most and how to combine them safely after 60. 5 Science-Backed Exercises That Reverse Aging is not about extreme workouts. It is about giving your body regular signals to stay strong, capable, and metabolically active. THE 5 EXERCISE STRATEGIES: 1. BRISK WALKING & MODERATE AEROBIC EXERCISE Walking at a pace that noticeably increases breathing trains your heart and lungs while improving endurance and everyday mobility. Start with 10 minutes if necessary and gradually work toward longer sessions. 2. INTERVAL TRAINING Alternating easier movement with short periods of higher effort can produce strong improvements in cardiorespiratory fitness. For example: three minutes of brisk walking followed by one minute at a faster pace, repeated several times. Older adults with cardiovascular disease or other significant medical conditions should discuss vigorous intervals with their healthcare professional first. 3. RESISTANCE TRAINING Chair squats, wall push-ups, resistance bands, rows, step-ups, and other progressive exercises can strengthen major muscle groups without requiring heavy gym equipment. WHO recommends muscle-strengthening activity involving all major muscle groups on at least two days per week. 4. STEADY ENDURANCE EXERCISE Longer moderate sessions of walking, swimming, cycling, or hiking help develop cardiovascular endurance and provide another stimulus for mitochondrial and metaboli https://www.youtube-nocookie.com/embed/WzWGvqqgfw4 1081 2026-09-14T17:06:43.000Z 2026-10-22T18:32:08.288Z https://longevityharbor.com/en/watch/X-Hzyzo1Jpk Creator's 2025 longevity research roundup: reprogramming, senescent cells, GLP-1s and more https://i.ytimg.com/vi/X-Hzyzo1Jpk/hqdefault.jpg The creator lists what she considers important 2025 contributions to longevity research, from cellular reprogramming and senescent cells to GLP-1 agonists, elastin fragments, a cardiac experiment, systemic-environment work and AI-designed antibodies. https://www.youtube-nocookie.com/embed/X-Hzyzo1Jpk 1382 2025-12-21T14:45:06.000Z 2026-10-23T03:14:26.341Z https://longevityharbor.com/de/watch/X-Hzyzo1Jpk Rückblick des Kanals auf die Longevity-Forschung 2025: Reprogrammierung, seneszente Zellen, GLP-1 un https://i.ytimg.com/vi/X-Hzyzo1Jpk/hqdefault.jpg Die Kanalbetreiberin listet, was sie als wichtige Beiträge zur Longevity-Forschung 2025 ansieht – von zellulärer Reprogrammierung und seneszenten Zellen über GLP-1-Agonisten, Elastin-Fragmente und ein Herz-Experiment bis zu Arbeiten zum systemischen Umfeld und KI-entworfenen Antikörpern. https://www.youtube-nocookie.com/embed/X-Hzyzo1Jpk 1382 2025-12-21T14:45:06.000Z 2026-10-23T03:14:26.341Z https://longevityharbor.com/en/watch/X1mrvhIkIEU Social Hallmarks of Aging: Evidence from the Health and Retirement Study https://i.ytimg.com/vi/X1mrvhIkIEU/hqdefault.jpg University of Southern California's Eileen Crimmins, PhD, visits the IOA to discuss her research on the social hallmarks of aging. https://www.youtube-nocookie.com/embed/X1mrvhIkIEU 224 2019-10-14T18:46:52.000Z 2026-10-22T17:43:40.109Z https://longevityharbor.com/de/watch/X1mrvhIkIEU Social Hallmarks of Aging: Evidence from the Health and Retirement Study https://i.ytimg.com/vi/X1mrvhIkIEU/hqdefault.jpg University of Southern California's Eileen Crimmins, PhD, visits the IOA to discuss her research on the social hallmarks of aging. https://www.youtube-nocookie.com/embed/X1mrvhIkIEU 224 2019-10-14T18:46:52.000Z 2026-10-22T17:43:40.109Z https://longevityharbor.com/en/watch/X2DH6GuUuj4 Video description: five exercises for aging capacities, not tested outcomes https://i.ytimg.com/vi/X2DH6GuUuj4/hqdefault.jpg The description presents five exercises said to target strength, cardiovascular fitness, balance, power and independence, and links lower-body strength and grip strength to healthy aging. It reports no study results. https://www.youtube-nocookie.com/embed/X2DH6GuUuj4 1392 2026-10-04T16:00:30.000Z 2026-10-22T21:23:42.244Z https://longevityharbor.com/de/watch/X2DH6GuUuj4 Videobeschreibung: fünf Übungen für Altersfähigkeiten, keine geprüften Ergebnisse https://i.ytimg.com/vi/X2DH6GuUuj4/hqdefault.jpg Die Beschreibung stellt fünf Übungen vor, die auf Kraft, Herz-Kreislauf-Fitness, Balance, Power und Selbstständigkeit zielen sollen, und verknüpft Kraft der unteren Körperhälfte sowie Griffkraft mit gesundem Altern. Studienergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/X2DH6GuUuj4 1392 2026-10-04T16:00:30.000Z 2026-10-22T21:23:42.244Z https://longevityharbor.com/en/watch/X2ht9Kw7UsY Video description on geroscience after 50: clocks, zombie cells and sleep https://i.ytimg.com/vi/X2ht9Kw7UsY/hqdefault.jpg The description says Robert Evans, a senior health researcher, presents 2026 geroscience data on biological age, senescent 'zombie cells', mitochondria, autophagy, controlled stress and sleep; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/X2ht9Kw7UsY 889 2026-05-13T00:27:09.000Z 2026-10-23T01:06:37.432Z https://longevityharbor.com/de/watch/X2ht9Kw7UsY Videobeschreibung zu Geroscience ab 50: Uhren, Zombiezellen und Schlaf https://i.ytimg.com/vi/X2ht9Kw7UsY/hqdefault.jpg Laut Beschreibung stellt Robert Evans, Senior Health Researcher, Geroscience-Daten aus 2026 zu biologischem Alter, seneszenten „Zombiezellen“, Mitochondrien, Autophagie, kontrolliertem Stress und Schlaf vor; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/X2ht9Kw7UsY 889 2026-05-13T00:27:09.000Z 2026-10-23T01:06:37.432Z https://longevityharbor.com/en/watch/X3eU_C0iZj4 Ernährungsdoc Matthias Riedl: Longevity / 15 - 25 Jahre länger leben mit gesunder Ernährung https://i.ytimg.com/vi/X3eU_C0iZj4/hqdefault.jpg Longevity, also Langlebigkeit liegt im Trend. Der Ernährungs-Doc erklärt, was wirklich hilft Alle möchten möglichst lang leben, aber niemand möchte sich dabei alt fühlen. Was es mit dem neuen Begriff „Longevity“ auf sich hat, darum geht es in den neuen Podcast-Folge Der Ernährungs-Doc hat dem Thema ein neues Buch gewidmet, das gerade erschienen ist. Die Ungleichheit in der Gesellschaft werde immer großer, sagt Matthias Riedl, weil sich immer mehr Leute schlecht ernährten. Vor allem immer mehr Jugendliche litten unter Zivilisationskrankheiten. „Deshalb tritt die Lebenserwartung auf der Stelle und vielleicht wird sie sogar rückläufig werden.“ Auf der anderen Seite seien die Menschen, die das Geld und das Wissen hätten, sich gesund zu ernähren. In dieser Folge gibt der Ernährungs-Mediziner folgende Tipps: Maßvoll Essen, Bauchfett reduzieren, Darmflora pflegen und Stress abbauen. Er erklärt auch, wie wichtig ein Sinn im Leben ist sowie Gemeinschaft und Sport, „damit kann man sich verjüngen“. Wer seinem Körper etwas Gutes tun möchte, sollte dieses Rezept ausprobieren: Wirsingpfanne mit Maronen aus: Matthias Riedl, Die Longevity-Food-Formel, Die richtige Ernährung als Erfolgsfaktor für ein langes und gesundes Leben. Gräfe und Unzer, 2025. Weitere Folgen unter https://www.abendblatt.de/podcast/dr-matthias-riedl-so-geht-gesunde-ernaehrung und auf YouTube unter https://www.youtube.com/playlist?list=PL2Ly-MZR_tF5fDOUl6Sb7Gx9vddTRqbLL. Das aktuelle Rezept findet Ihr mit dem Stichwort „Riedl-Podcast“ auf https://www.abendblatt.de/ im Text zu dieser Folge. Folgt uns auch gern auf Instagram https://bit.ly/44bbw1f. Auch dort laden wir in wenigen Tagen das Rezept hoch. https://www.youtube-nocookie.com/embed/X3eU_C0iZj4 2662 2025-03-15T18:00:22.000Z 2026-10-22T18:43:10.875Z https://longevityharbor.com/de/watch/X3eU_C0iZj4 Ernährungsdoc Matthias Riedl: Longevity / 15 - 25 Jahre länger leben mit gesunder Ernährung https://i.ytimg.com/vi/X3eU_C0iZj4/hqdefault.jpg Longevity, also Langlebigkeit liegt im Trend. Der Ernährungs-Doc erklärt, was wirklich hilft Alle möchten möglichst lang leben, aber niemand möchte sich dabei alt fühlen. Was es mit dem neuen Begriff „Longevity“ auf sich hat, darum geht es in den neuen Podcast-Folge Der Ernährungs-Doc hat dem Thema ein neues Buch gewidmet, das gerade erschienen ist. Die Ungleichheit in der Gesellschaft werde immer großer, sagt Matthias Riedl, weil sich immer mehr Leute schlecht ernährten. Vor allem immer mehr Jugendliche litten unter Zivilisationskrankheiten. „Deshalb tritt die Lebenserwartung auf der Stelle und vielleicht wird sie sogar rückläufig werden.“ Auf der anderen Seite seien die Menschen, die das Geld und das Wissen hätten, sich gesund zu ernähren. In dieser Folge gibt der Ernährungs-Mediziner folgende Tipps: Maßvoll Essen, Bauchfett reduzieren, Darmflora pflegen und Stress abbauen. Er erklärt auch, wie wichtig ein Sinn im Leben ist sowie Gemeinschaft und Sport, „damit kann man sich verjüngen“. Wer seinem Körper etwas Gutes tun möchte, sollte dieses Rezept ausprobieren: Wirsingpfanne mit Maronen aus: Matthias Riedl, Die Longevity-Food-Formel, Die richtige Ernährung als Erfolgsfaktor für ein langes und gesundes Leben. Gräfe und Unzer, 2025. Weitere Folgen unter https://www.abendblatt.de/podcast/dr-matthias-riedl-so-geht-gesunde-ernaehrung und auf YouTube unter https://www.youtube.com/playlist?list=PL2Ly-MZR_tF5fDOUl6Sb7Gx9vddTRqbLL. Das aktuelle Rezept findet Ihr mit dem Stichwort „Riedl-Podcast“ auf https://www.abendblatt.de/ im Text zu dieser Folge. Folgt uns auch gern auf Instagram https://bit.ly/44bbw1f. Auch dort laden wir in wenigen Tagen das Rezept hoch. https://www.youtube-nocookie.com/embed/X3eU_C0iZj4 2662 2025-03-15T18:00:22.000Z 2026-10-22T18:43:10.875Z https://longevityharbor.com/en/watch/X4EQJrSu9iQ Fastenhäppchen—Teil 14: "Fasten und Longevity" – mit Prof. Andreas Michalsen https://i.ytimg.com/vi/X4EQJrSu9iQ/hqdefault.jpg Longevity—wie kann man möglichst lange gesund leben? Und wie kann Fasten dabei helfen? Diesmal im Gespräch mit dem Experten Prof. Dr. Michalsen. • https://pubmed.ncbi.nlm.nih.gov/38292053/ (Hallmarks of Aging) • https://pubmed.ncbi.nlm.nih.gov/24606898/ (niedrige Proteinaufnahme) • https://pubmed.ncbi.nlm.nih.gov/39885870/ (qualitative Interviews bei Scheinfasten) Unsere Ausbildung zum medizinisch-therapeutischen Fasten für Ärzt*innen, Ernährungsfachkräfte und Apotheker*innen sowie unsere ärztlich begleiteten Fastenkurse findet ihr hier… • Website: https://integratives-fasten.de/ • Instagram: https://www.instagram.com/integratives_fasten/ https://www.youtube-nocookie.com/embed/X4EQJrSu9iQ 2018 2025-11-27T03:53:57.000Z 2026-10-22T19:32:41.915Z https://longevityharbor.com/de/watch/X4EQJrSu9iQ Fastenhäppchen—Teil 14: "Fasten und Longevity" – mit Prof. Andreas Michalsen https://i.ytimg.com/vi/X4EQJrSu9iQ/hqdefault.jpg Longevity—wie kann man möglichst lange gesund leben? Und wie kann Fasten dabei helfen? Diesmal im Gespräch mit dem Experten Prof. Dr. Michalsen. • https://pubmed.ncbi.nlm.nih.gov/38292053/ (Hallmarks of Aging) • https://pubmed.ncbi.nlm.nih.gov/24606898/ (niedrige Proteinaufnahme) • https://pubmed.ncbi.nlm.nih.gov/39885870/ (qualitative Interviews bei Scheinfasten) Unsere Ausbildung zum medizinisch-therapeutischen Fasten für Ärzt*innen, Ernährungsfachkräfte und Apotheker*innen sowie unsere ärztlich begleiteten Fastenkurse findet ihr hier… • Website: https://integratives-fasten.de/ • Instagram: https://www.instagram.com/integratives_fasten/ https://www.youtube-nocookie.com/embed/X4EQJrSu9iQ 2018 2025-11-27T03:53:57.000Z 2026-10-22T19:32:41.915Z https://longevityharbor.com/en/watch/X6A4pcfciKc Unlocking the Power of Senolytics: Anti-Aging Breakthroughs Explained | Episode 1 https://i.ytimg.com/vi/X6A4pcfciKc/hqdefault.jpg ❤️ Support our work: https://buymeacoffee.com/nbulai Welcome to Episode 1 of our Deep Dive series! 🌟 In this video, we explore the fascinating world of senolytics and their role in anti-aging research. Learn how these "zombie cell slayers" could transform our understanding of aging and health. 🔗 💡 Sources and references: https://scicorn.nbulai.com or http://nbulai.com/podcast. 📅 Stay tuned for future episodes as we explore cutting-edge science and innovation. Chapters/Timestamps 0:00 Introduction to Senolytics 3:15 What are Zombie Cells? 7:30 How Senolytics Work 12:00 Promising Compounds: Fisetin, D+Q, and FOXO4-DRI 18:45 Challenges in Senolytic Research 25:00 Future Possibilities and Closing Thoughts 🔬 Topics Covered: What are senolytics? The science of cellular senescence Promising treatments like Fisetin, Dasatinib, and FOXO4-DRI Challenges and breakthroughs in senolytic research The future of anti-aging therapies 🧠 #AntiAging #Longevity #HealthyAging #Healthspan #AgingResearch #AgeReversal #Senescence #Senolytics #CellularSenescence #Rejuvenation #ScientificBreakthroughs #FutureMedicine #SciencePodcast #MedicalResearch #Biotechnology #life #podcast #sciencepodcast #scientificpodcast #scicorn #sciconpodcast #nbulai #nbulaipodcast #Fisetin #Dasatinib #AntiAgingDrugs #LongevityScience #ZombieCells #LifespanExtension #dontdie #healthylife #biology #medicaldrugs #medicine #aging #aginggracefully #Science #Technology #Innovation #Research #FutureOfMedicine #HealthInnovation #CuttingEdgeScience #Breakthroughs https://www.youtube-nocookie.com/embed/X6A4pcfciKc 1851 2024-12-27T17:09:04.000Z 2026-10-22T19:21:23.033Z https://longevityharbor.com/de/watch/X6A4pcfciKc Unlocking the Power of Senolytics: Anti-Aging Breakthroughs Explained | Episode 1 https://i.ytimg.com/vi/X6A4pcfciKc/hqdefault.jpg ❤️ Support our work: https://buymeacoffee.com/nbulai Welcome to Episode 1 of our Deep Dive series! 🌟 In this video, we explore the fascinating world of senolytics and their role in anti-aging research. Learn how these "zombie cell slayers" could transform our understanding of aging and health. 🔗 💡 Sources and references: https://scicorn.nbulai.com or http://nbulai.com/podcast. 📅 Stay tuned for future episodes as we explore cutting-edge science and innovation. Chapters/Timestamps 0:00 Introduction to Senolytics 3:15 What are Zombie Cells? 7:30 How Senolytics Work 12:00 Promising Compounds: Fisetin, D+Q, and FOXO4-DRI 18:45 Challenges in Senolytic Research 25:00 Future Possibilities and Closing Thoughts 🔬 Topics Covered: What are senolytics? The science of cellular senescence Promising treatments like Fisetin, Dasatinib, and FOXO4-DRI Challenges and breakthroughs in senolytic research The future of anti-aging therapies 🧠 #AntiAging #Longevity #HealthyAging #Healthspan #AgingResearch #AgeReversal #Senescence #Senolytics #CellularSenescence #Rejuvenation #ScientificBreakthroughs #FutureMedicine #SciencePodcast #MedicalResearch #Biotechnology #life #podcast #sciencepodcast #scientificpodcast #scicorn #sciconpodcast #nbulai #nbulaipodcast #Fisetin #Dasatinib #AntiAgingDrugs #LongevityScience #ZombieCells #LifespanExtension #dontdie #healthylife #biology #medicaldrugs #medicine #aging #aginggracefully #Science #Technology #Innovation #Research #FutureOfMedicine #HealthInnovation #CuttingEdgeScience #Breakthroughs https://www.youtube-nocookie.com/embed/X6A4pcfciKc 1851 2024-12-27T17:09:04.000Z 2026-10-22T19:21:23.033Z https://longevityharbor.com/en/watch/XB6B_XjQMa8 Video description compares NR and NMN NAD⁺ evidence and mixed trial results https://i.ytimg.com/vi/XB6B_XjQMa8/hqdefault.jpg The description cites a small crossover trial in which NR raised blood NAD more than NMN, a larger trial finding comparable NAD doubling, and meta-analyses and trials reporting little or no benefit on muscle, metabolic or long-COVID outcomes. https://www.youtube-nocookie.com/embed/XB6B_XjQMa8 639 2026-04-03T11:46:01.000Z 2026-10-23T01:45:33.691Z https://longevityharbor.com/de/watch/XB6B_XjQMa8 Videobeschreibung vergleicht NR- und NMN-NAD⁺-Belege und gemischte Studienergebnisse https://i.ytimg.com/vi/XB6B_XjQMa8/hqdefault.jpg Die Beschreibung nennt eine kleine Crossover-Studie, in der NR den Blut-NAD-Wert stärker erhöhte als NMN, eine größere Studie mit vergleichbarer NAD-Verdopplung sowie Metaanalysen und Studien mit kaum oder keinem Nutzen für Muskel-, Stoffwechsel- oder Long-COVID-Ergebnisse. https://www.youtube-nocookie.com/embed/XB6B_XjQMa8 639 2026-04-03T11:46:01.000Z 2026-10-23T01:45:33.691Z https://longevityharbor.com/en/watch/XBrIPr9htyI Unlocking the Secrets of the Epigenetic Clock https://i.ytimg.com/vi/XBrIPr9htyI/hqdefault.jpg Unlocking the Secrets of the Epigenetic Clock https://www.youtube-nocookie.com/embed/XBrIPr9htyI 137 2025-05-16T10:57:31.000Z 2026-10-22T19:21:27.682Z https://longevityharbor.com/de/watch/XBrIPr9htyI Unlocking the Secrets of the Epigenetic Clock https://i.ytimg.com/vi/XBrIPr9htyI/hqdefault.jpg Unlocking the Secrets of the Epigenetic Clock https://www.youtube-nocookie.com/embed/XBrIPr9htyI 137 2025-05-16T10:57:31.000Z 2026-10-22T19:21:27.682Z https://longevityharbor.com/en/watch/XF-Wavn0YhU Fasten & Eisbaden: Mit Biohacking das Altern stoppen? | Terra Xplore mit Biologin Jasmina Neudecker https://i.ytimg.com/vi/XF-Wavn0YhU/hqdefault.jpg Einmal pro Woche ins Eis-Fass und schon friert auch die biologische Uhr ein und hält den Alterungsprozess auf?! 👵🚫 Diese Creme, dieses Superfood, diese Morgenroutine und zack - schon bist du 5 Jahre jünger! Oft klingen sie einfach, die zahlreichen Tipps und Tricks rund um das Thema "Altern stoppen, jung bleiben". Die Menge an wissenschaftlich ungeprüften Aussagen auf Social Media deutet auf ein tiefes Bedürfnis hin, mit nur etwas mehr Selbstoptimierung jung, fit und gesund zu bleiben. Jasmina Neudecker schaut sich das Thema mal durch die wissenschaftliche Brille an: Wo steht die Forschung? Was ist Altern überhaupt? Und was können wir tun, um das Altern zu verlangsamen? Dafür trifft sich Jasmina mit Altersforschenden, die die komplexen Prozesse des Alterns entschlüsseln wollen. Und sie trifft eine Frau, die versucht, die Hinweise aus der Wissenschaft in ihren Alltag einzubauen: Biohackerin Beate Proske. Welcher Routine folgt sie und wie sieht Biohacking für sie in der Praxis aus? Von Beate Proske bekommt Jasmina Biohacking Tipps und steigt mit ihr in 4 Grad kaltes Wasser. Ist Eisbaden wirklich gesund, welche Vorteile bringt es und kann es unsere biologische Uhr zurückdrehen? Und welche Rolle spielt die Ernährung? Fasten nicht nur zum Abnehmen, sondern um sich zu verjüngen? Was passiert beim Fasten im Körper? Jasmina besucht zu dieser Frage Dr. Roberto Ripa und seine Killifische. Die Forschung zeigt spannende Erkenntnisse, wie Fasten vielleicht dabei helfen kann, das Altern zu verlangsamen. 🧊 Dieser Film ist Teil der Terra Xplore-Staffel „Über_Leben“ mit Biologin Jasmina Neudecker: https://www.zdf.de/dokumentation/terra-xplore/xplore-ueber-leben-102.html?at_medium=Social%20Media&at_campaign=YouTube&at_specific=TerraX&at_content=Xplore ******* KAPITEL: 00:00 Intro 00:59 Was ist Biohacking und warum macht man das? 03:18 Was passiert beim Altern in unseren Zellen? 06:35 Wie kann man das genetische Alter messen? 07:06 Wie kann uns Biohacking helfen, das Altern zu verlangsamen? 07:32 Wie fühlt sich Eisbaden https://www.youtube-nocookie.com/embed/XF-Wavn0YhU 1630 2023-11-16T13:00:25.000Z 2026-10-22T18:54:06.982Z https://longevityharbor.com/de/watch/XF-Wavn0YhU Fasten & Eisbaden: Mit Biohacking das Altern stoppen? | Terra Xplore mit Biologin Jasmina Neudecker https://i.ytimg.com/vi/XF-Wavn0YhU/hqdefault.jpg Einmal pro Woche ins Eis-Fass und schon friert auch die biologische Uhr ein und hält den Alterungsprozess auf?! 👵🚫 Diese Creme, dieses Superfood, diese Morgenroutine und zack - schon bist du 5 Jahre jünger! Oft klingen sie einfach, die zahlreichen Tipps und Tricks rund um das Thema "Altern stoppen, jung bleiben". Die Menge an wissenschaftlich ungeprüften Aussagen auf Social Media deutet auf ein tiefes Bedürfnis hin, mit nur etwas mehr Selbstoptimierung jung, fit und gesund zu bleiben. Jasmina Neudecker schaut sich das Thema mal durch die wissenschaftliche Brille an: Wo steht die Forschung? Was ist Altern überhaupt? Und was können wir tun, um das Altern zu verlangsamen? Dafür trifft sich Jasmina mit Altersforschenden, die die komplexen Prozesse des Alterns entschlüsseln wollen. Und sie trifft eine Frau, die versucht, die Hinweise aus der Wissenschaft in ihren Alltag einzubauen: Biohackerin Beate Proske. Welcher Routine folgt sie und wie sieht Biohacking für sie in der Praxis aus? Von Beate Proske bekommt Jasmina Biohacking Tipps und steigt mit ihr in 4 Grad kaltes Wasser. Ist Eisbaden wirklich gesund, welche Vorteile bringt es und kann es unsere biologische Uhr zurückdrehen? Und welche Rolle spielt die Ernährung? Fasten nicht nur zum Abnehmen, sondern um sich zu verjüngen? Was passiert beim Fasten im Körper? Jasmina besucht zu dieser Frage Dr. Roberto Ripa und seine Killifische. Die Forschung zeigt spannende Erkenntnisse, wie Fasten vielleicht dabei helfen kann, das Altern zu verlangsamen. 🧊 Dieser Film ist Teil der Terra Xplore-Staffel „Über_Leben“ mit Biologin Jasmina Neudecker: https://www.zdf.de/dokumentation/terra-xplore/xplore-ueber-leben-102.html?at_medium=Social%20Media&at_campaign=YouTube&at_specific=TerraX&at_content=Xplore ******* KAPITEL: 00:00 Intro 00:59 Was ist Biohacking und warum macht man das? 03:18 Was passiert beim Altern in unseren Zellen? 06:35 Wie kann man das genetische Alter messen? 07:06 Wie kann uns Biohacking helfen, das Altern zu verlangsamen? 07:32 Wie fühlt sich Eisbaden https://www.youtube-nocookie.com/embed/XF-Wavn0YhU 1630 2023-11-16T13:00:25.000Z 2026-10-22T18:54:06.982Z https://longevityharbor.com/en/watch/XFH1sspNkug Epigenetic clocks in HIV: statin-stabilized aging rate and semaglutide response prediction https://i.ytimg.com/vi/XFH1sspNkug/hqdefault.jpg In the described presentation, two clinical studies in people living with HIV used DNA methylation clocks: pitavastatin stabilized the rate of biological aging over 24 months versus placebo, and baseline epigenetic age predicted semaglutide response. https://www.youtube-nocookie.com/embed/XFH1sspNkug 2014 2026-01-24T23:09:57.000Z 2026-10-23T02:46:32.500Z https://longevityharbor.com/de/watch/XFH1sspNkug Epigenetische Uhren bei HIV: Statin-stabilisierte Alterungsrate und Vorhersage des Semaglutid-Anspre https://i.ytimg.com/vi/XFH1sspNkug/hqdefault.jpg In der beschriebenen Präsentation nutzten zwei klinische Studien bei Menschen mit HIV DNA-Methylierungs-Uhren: Pitavastatin stabilisierte die Rate der biologischen Alterung über 24 Monate gegenüber Placebo, und das epigenetische Alter zu Studienbeginn sagte das Semaglutid-Ansprechen voraus. https://www.youtube-nocookie.com/embed/XFH1sspNkug 2014 2026-01-24T23:09:57.000Z 2026-10-23T02:46:32.500Z https://longevityharbor.com/en/watch/XJufAGjhDy8 The Science Behind Robles BioCeutics' New Publication: Senolytics, Stem Cells, and Skin Repair https://i.ytimg.com/vi/XJufAGjhDy8/hqdefault.jpg Maria Robles, CEO of @RoblesBioCeutics, joins Dr. Navneet Boddu to discuss their newly published peer-reviewed paper in The Journal of Translational Medicine. This milestone marks a major step forward for the company’s mission to advance regenerative dermatology through senolytic science and stem cell inspired innovation. In this video, Maria and Dr. Boddu break down: - The key findings from their publication “Unleashing Endogenous Regeneration by Senolytics” - How senescent cells block natural repair processes in the skin - Why combining senolytics with regenerative signals represents a new frontier in anti-aging - How Robles BioCeutics is building the next generation of science-driven skincare This is a must-watch for anyone interested in the future of skin health, regenerative medicine, and the science behind true anti-aging innovation. Publication: Unleashing endogenous regeneration by senolytics Read here- https://link.springer.com/article/10.1186/s12967-025-07398-y 🔔 Follow Robles BioCeutics for more updates: Instagram: https://www.instagram.com/rbioceutics Twitter: https://x.com/RBioceutics Facebook: https://www.facebook.com/profile.php?id=61566327543069 Website: https://roblesbioceutics.com Stay tuned for more scientific insights and updates from Robles BioCeutics! https://www.youtube-nocookie.com/embed/XJufAGjhDy8 169 2025-11-26T20:00:06.000Z 2026-10-22T19:43:47.764Z https://longevityharbor.com/de/watch/XJufAGjhDy8 The Science Behind Robles BioCeutics' New Publication: Senolytics, Stem Cells, and Skin Repair https://i.ytimg.com/vi/XJufAGjhDy8/hqdefault.jpg Maria Robles, CEO of @RoblesBioCeutics, joins Dr. Navneet Boddu to discuss their newly published peer-reviewed paper in The Journal of Translational Medicine. This milestone marks a major step forward for the company’s mission to advance regenerative dermatology through senolytic science and stem cell inspired innovation. In this video, Maria and Dr. Boddu break down: - The key findings from their publication “Unleashing Endogenous Regeneration by Senolytics” - How senescent cells block natural repair processes in the skin - Why combining senolytics with regenerative signals represents a new frontier in anti-aging - How Robles BioCeutics is building the next generation of science-driven skincare This is a must-watch for anyone interested in the future of skin health, regenerative medicine, and the science behind true anti-aging innovation. Publication: Unleashing endogenous regeneration by senolytics Read here- https://link.springer.com/article/10.1186/s12967-025-07398-y 🔔 Follow Robles BioCeutics for more updates: Instagram: https://www.instagram.com/rbioceutics Twitter: https://x.com/RBioceutics Facebook: https://www.facebook.com/profile.php?id=61566327543069 Website: https://roblesbioceutics.com Stay tuned for more scientific insights and updates from Robles BioCeutics! https://www.youtube-nocookie.com/embed/XJufAGjhDy8 169 2025-11-26T20:00:06.000Z 2026-10-22T19:43:47.764Z https://longevityharbor.com/en/watch/XPDYaHFXHxk Video description: rapamycin, mTOR and the human evidence https://i.ytimg.com/vi/XPDYaHFXHxk/hqdefault.jpg The description presents a plain-language series episode on mTOR as a growth switch, what rapamycin does, and the human evidence with its trade-offs; it gives no results. https://www.youtube-nocookie.com/embed/XPDYaHFXHxk 204 2026-07-20T03:46:24.000Z 2026-10-22T23:29:26.664Z https://longevityharbor.com/de/watch/XPDYaHFXHxk Videobeschreibung: Rapamycin, mTOR und die menschliche Evidenz https://i.ytimg.com/vi/XPDYaHFXHxk/hqdefault.jpg Die Beschreibung stellt eine einfach erklärte Serienfolge über mTOR als Wachstumsschalter, die Wirkung von Rapamycin und die menschliche Evidenz mit ihren Abwägungen vor; Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/XPDYaHFXHxk 204 2026-07-20T03:46:24.000Z 2026-10-22T23:29:26.664Z https://longevityharbor.com/en/watch/Xcf_Ct0GMBc Video description on longevity and rapamycin from a functional medicine doctor https://i.ytimg.com/vi/Xcf_Ct0GMBc/hqdefault.jpg The description announces a talk about longevity and rapamycin and invites viewers to message the creator to schedule an intake. It gives no study results, doses or evidence about effects. https://www.youtube-nocookie.com/embed/Xcf_Ct0GMBc 117 2026-02-21T18:18:03.000Z 2026-10-23T02:27:40.827Z https://longevityharbor.com/de/watch/Xcf_Ct0GMBc Videobeschreibung zu Langlebigkeit und Rapamycin von einer Ärztin für funktionelle Medizin https://i.ytimg.com/vi/Xcf_Ct0GMBc/hqdefault.jpg Die Beschreibung kündigt ein Gespräch über Langlebigkeit und Rapamycin an und lädt Zuschauer ein, die Erstellerin anzuschreiben, um einen Aufnahmetermin zu vereinbaren. Ergebnisse, Dosierungen oder Belege zu Wirkungen nennt sie nicht. https://www.youtube-nocookie.com/embed/Xcf_Ct0GMBc 117 2026-02-21T18:18:03.000Z 2026-10-23T02:27:40.827Z https://longevityharbor.com/en/watch/XdmgWmn8u7E Podcast description: circadian clock, aging, sleep and sugar-damage claims https://i.ytimg.com/vi/XdmgWmn8u7E/hqdefault.jpg The description says Dr. Sandra Kaufmann explains a failing cellular circadian clock as a reason people cannot sleep, how aging changes sleep, and how glucose and fructose are said to speed aging; these are creator claims, not verified findings. https://www.youtube-nocookie.com/embed/XdmgWmn8u7E 3298 2025-11-27T15:00:06.000Z 2026-10-23T03:23:39.103Z https://longevityharbor.com/de/watch/XdmgWmn8u7E Podcast-Beschreibung: circadiane Uhr, Altern, Schlaf und Zucker-Schäden https://i.ytimg.com/vi/XdmgWmn8u7E/hqdefault.jpg Laut Beschreibung erklärt Dr. Sandra Kaufmann eine versagende circadiane Uhr auf Zellebene als Grund für Schlafprobleme, wie sich Schlaf mit dem Alter verändert und dass Glucose und Fructose das Altern beschleunigen sollen; das sind Aussagen der Macher, keine geprüften Ergebnisse. https://www.youtube-nocookie.com/embed/XdmgWmn8u7E 3298 2025-11-27T15:00:06.000Z 2026-10-23T03:23:39.103Z https://longevityharbor.com/en/watch/XkBQ4R0MkQg Physio video description lists 7 exercises claimed to reverse age-related decline after 40 https://i.ytimg.com/vi/XkBQ4R0MkQg/hqdefault.jpg The description presents seven bodyweight exercises, from dead hang to side plank, and claims they can reverse decline after 40, some within weeks. No study details, participants or results are given. https://www.youtube-nocookie.com/embed/XkBQ4R0MkQg 375 2026-08-20T14:00:09.000Z 2026-10-22T22:55:53.769Z https://longevityharbor.com/de/watch/XkBQ4R0MkQg Physio-Videobeschreibung nennt 7 Übungen, die altersassoziierten Abbau nach 40 umkehren sollen https://i.ytimg.com/vi/XkBQ4R0MkQg/hqdefault.jpg Die Beschreibung stellt sieben Körpergewichtsübungen vor, vom Dead Hang bis zum Side Plank, und behauptet, sie könnten den Abbau nach 40 umkehren, teils innerhalb von Wochen. Studiendetails, Teilnehmende oder Ergebnisse fehlen. https://www.youtube-nocookie.com/embed/XkBQ4R0MkQg 375 2026-08-20T14:00:09.000Z 2026-10-22T22:55:53.769Z https://longevityharbor.com/en/watch/XkNJEa4UrfE Video description: six proposed evening inputs after 50 https://i.ytimg.com/vi/XkNJEa4UrfE/hqdefault.jpg The description says the video covers why overnight repair is said to decline after 50 and six evening inputs: meal timing, blue light, a warm shower, the vagus nerve, nasal breathing and an extended exhale. https://www.youtube-nocookie.com/embed/XkNJEa4UrfE 1660 2026-06-29T12:00:24.000Z 2026-10-22T23:42:28.625Z https://longevityharbor.com/de/watch/XkNJEa4UrfE Videobeschreibung: sechs vorgeschlagene Abend-Inputs nach 50 https://i.ytimg.com/vi/XkNJEa4UrfE/hqdefault.jpg Laut Beschreibung behandelt das Video, warum die nächtliche Reparatur nach 50 angeblich abnimmt, und sechs Abend-Inputs: Essenszeitpunkt, blaues Licht, warme Dusche, Vagusnerv, Nasenatmung und verlängertes Ausatmen. https://www.youtube-nocookie.com/embed/XkNJEa4UrfE 1660 2026-06-29T12:00:24.000Z 2026-10-22T23:42:28.625Z https://longevityharbor.com/en/watch/XlURhiiwMT8 SRN-901 in aging mice: 33% lifespan gain versus rapamycin, NMN and NR https://i.ytimg.com/vi/XlURhiiwMT8/hqdefault.jpg The description says the compound SRN-901 extended lifespan in mice by 33% and outperformed rapamycin, NMN and NR in a head-to-head comparison. These are mouse results from one paper, not evidence of benefit for human lifespan. https://www.youtube-nocookie.com/embed/XlURhiiwMT8 321 2026-05-29T17:35:18.000Z 2026-10-23T00:18:31.288Z https://longevityharbor.com/de/watch/XlURhiiwMT8 SRN-901 bei alternden Mäusen: 33 % längere Lebensspanne gegenüber Rapamycin, NMN und NR https://i.ytimg.com/vi/XlURhiiwMT8/hqdefault.jpg Laut Beschreibung verlängerte die Substanz SRN-901 die Lebensspanne von Mäusen um 33 % und übertraf in einem direkten Vergleich Rapamycin, NMN und NR. Das sind Mausergebnisse aus einer Arbeit, kein Beleg für einen Nutzen für die menschliche Lebensspanne. https://www.youtube-nocookie.com/embed/XlURhiiwMT8 321 2026-05-29T17:35:18.000Z 2026-10-23T00:18:31.288Z https://longevityharbor.com/en/watch/Xox902-N4Lo Fasting Mimetics and What Are the Effects on Hunger, Cholesterol, Glucose, and Aging Well? | Ep. 250 https://i.ytimg.com/vi/Xox902-N4Lo/hqdefault.jpg In this episode of 'The Aging Well Podcast', Dr. Jeff Armstrong's guest is Dr. Christopher Rhodes, founder and CEO of Mimio Health, a biomimetic supplement company focused on recreating the benefits of fasting through a daily supplement. Dr. Rhodes explains the science behind fasting, its effects on aging, and how Mimeo's unique formulation mimics the biochemical processes that occur during fasting. The discussion also covers recent clinical studies, unexpected findings, and the practical benefits of Mimio for users, including appetite suppression and improved metabolic health. Additionally, insights into demographic differences in response to Mimeo and comparisons to traditional fasting methods are explored. The discussion explores its potential for enhancing athletic performance, its incorporation into daily routines, and its implications for various populations, including those with metabolic conditions. Dr. Rhodes emphasizes the importance of scientific integrity in the supplement industry and outlines future research directions for Mimio. He also highlights the distinction between maintaining healthspan and lifespan, advocating for a holistic approach to healthy aging. Learn more about Dr. Rhodes and Mimio Health at: https://mimiohealth.com/ BUY the products you need to… age well from our trusted affiliates and support the mission of ‘The Aging Well Podcast’*: Thrive25—Your personal longevity advisor | https://www.thrive25.com/early-access?via=william-jeffrey TruDiagnostic—Your source for epigenetic testing | Code: AGEWELL | https://shop.trudiagnostic.com/discount/AGEWELL Fusionary Formulas | Combining Ayurvedic wisdom with Western science for optimal health support. | Code: AGINGWELL | https://fusionaryformulas.com/ *We receive commission on these purchases. Thank you. https://www.youtube-nocookie.com/embed/Xox902-N4Lo 3433 2025-05-04T12:08:29.000Z 2026-10-22T19:54:18.280Z https://longevityharbor.com/de/watch/Xox902-N4Lo Fasting Mimetics and What Are the Effects on Hunger, Cholesterol, Glucose, and Aging Well? | Ep. 250 https://i.ytimg.com/vi/Xox902-N4Lo/hqdefault.jpg In this episode of 'The Aging Well Podcast', Dr. Jeff Armstrong's guest is Dr. Christopher Rhodes, founder and CEO of Mimio Health, a biomimetic supplement company focused on recreating the benefits of fasting through a daily supplement. Dr. Rhodes explains the science behind fasting, its effects on aging, and how Mimeo's unique formulation mimics the biochemical processes that occur during fasting. The discussion also covers recent clinical studies, unexpected findings, and the practical benefits of Mimio for users, including appetite suppression and improved metabolic health. Additionally, insights into demographic differences in response to Mimeo and comparisons to traditional fasting methods are explored. The discussion explores its potential for enhancing athletic performance, its incorporation into daily routines, and its implications for various populations, including those with metabolic conditions. Dr. Rhodes emphasizes the importance of scientific integrity in the supplement industry and outlines future research directions for Mimio. He also highlights the distinction between maintaining healthspan and lifespan, advocating for a holistic approach to healthy aging. Learn more about Dr. Rhodes and Mimio Health at: https://mimiohealth.com/ BUY the products you need to… age well from our trusted affiliates and support the mission of ‘The Aging Well Podcast’*: Thrive25—Your personal longevity advisor | https://www.thrive25.com/early-access?via=william-jeffrey TruDiagnostic—Your source for epigenetic testing | Code: AGEWELL | https://shop.trudiagnostic.com/discount/AGEWELL Fusionary Formulas | Combining Ayurvedic wisdom with Western science for optimal health support. | Code: AGINGWELL | https://fusionaryformulas.com/ *We receive commission on these purchases. Thank you. https://www.youtube-nocookie.com/embed/Xox902-N4Lo 3433 2025-05-04T12:08:29.000Z 2026-10-22T19:54:18.280Z https://longevityharbor.com/en/watch/XsWs120XTtw Video description on 50 years of aging research and biological age https://i.ytimg.com/vi/XsWs120XTtw/hqdefault.jpg The description says the video covers 50 years of research on aging, distinguishing chronological from biological age and presenting lifestyle, alpha-ketoglutarate and plasma exchange as interventions, plus the planned TAME trial. https://www.youtube-nocookie.com/embed/XsWs120XTtw 521 2026-02-15T10:37:04.000Z 2026-10-23T02:30:10.518Z https://longevityharbor.com/de/watch/XsWs120XTtw Videobeschreibung zu 50 Jahren Alternsforschung und biologischem Alter https://i.ytimg.com/vi/XsWs120XTtw/hqdefault.jpg Laut Beschreibung behandelt das Video 50 Jahre Alternsforschung, unterscheidet chronologisches von biologischem Alter und nennt Lebensstil, Alpha-Ketoglutarat und Plasmaaustausch als Interventionen sowie die geplante TAME-Studie. https://www.youtube-nocookie.com/embed/XsWs120XTtw 521 2026-02-15T10:37:04.000Z 2026-10-23T02:30:10.518Z https://longevityharbor.com/en/watch/Xuhc5g7rcjo John Newman at ARDD2025: translational geroscience talk on training, centers and clinical applicatio https://i.ytimg.com/vi/Xuhc5g7rcjo/hqdefault.jpg The description says John Newman of the Buck Institute presents at the 12th Aging Research and Drug Discovery meeting on accelerating translational geroscience through new training programs, centers and clinical applications. https://www.youtube-nocookie.com/embed/Xuhc5g7rcjo 1354 2026-01-22T20:08:06.000Z 2026-10-23T02:48:17.777Z https://longevityharbor.com/de/watch/Xuhc5g7rcjo John Newman bei ARDD2025: Vortrag zur translationalen Geroscience über Ausbildung, Zentren und klini https://i.ytimg.com/vi/Xuhc5g7rcjo/hqdefault.jpg Laut Beschreibung spricht John Newman vom Buck Institute auf dem 12. Aging Research and Drug Discovery Meeting darüber, wie translationale Geroscience durch neue Ausbildungsprogramme, Zentren und klinische Anwendungen beschleunigt werden soll. https://www.youtube-nocookie.com/embed/Xuhc5g7rcjo 1354 2026-01-22T20:08:06.000Z 2026-10-23T02:48:17.777Z https://longevityharbor.com/en/watch/XvDNpdn_b9A Podcast description: mitochondria, Urolithin A and a sponsored supplement https://i.ytimg.com/vi/XvDNpdn_b9A/hqdefault.jpg The description presents a podcast episode in which dietitian Jennifer Scheinman discusses mitochondria, mitophagy, Urolithin A and Timeline's MitoPure; the episode is sponsored by Timeline. https://www.youtube-nocookie.com/embed/XvDNpdn_b9A 3944 2026-05-19T20:01:35.000Z 2026-10-23T00:38:15.593Z https://longevityharbor.com/de/watch/XvDNpdn_b9A Podcast-Beschreibung: Mitochondrien, Urolithin A und ein gesponsertes Präparat https://i.ytimg.com/vi/XvDNpdn_b9A/hqdefault.jpg Die Beschreibung stellt eine Podcast-Folge vor, in der die Ernährungsberaterin Jennifer Scheinman Mitochondrien, Mitophagie, Urolithin A und MitoPure von Timeline bespricht; die Folge wird von Timeline gesponsert. https://www.youtube-nocookie.com/embed/XvDNpdn_b9A 3944 2026-05-19T20:01:35.000Z 2026-10-23T00:38:15.593Z https://longevityharbor.com/en/watch/XvR7Fh2CCts How to take NMN for longevity (women over 50) https://i.ytimg.com/vi/XvR7Fh2CCts/hqdefault.jpg In this video, longevity expert Jill Ritchie explains why she's been taking NMN for over 1 year, and reveals her NAD test results. ACCESS FULL SUPPLEMENT LIST HERE ➡️https://www.jillritchie.com/stack ⬅️ J-Infiniti NAD Test: 10% off code “jillritchie” https://snip.ly/fi9sgx J-Infiniti NMN Powder: 10% off code “jillritchie” https://snip.ly/84s65l ProHealth NMN Capsules https://snip.ly/x55gqs RESEARCH PROCESS Want to know how we do our research and why I'm a longevity expert? https://www.jillritchie.com/process Private coaching (limited seats) https://forms.gle/EvyQ2Tm9KTcHRscz9 Promix protein: 10% off code “jillritchie” https://snip.ly/1q3cko $350 off Eight Sleep pod http://snip.ly/8sleep InsideTracker https://snip.ly/y7sa80 Oura Ring https://snip.ly/kfy0bu SoulCycle x Equinox https://snip.ly/6cimjx Jinfiniti: 10% off code "jillritchie" https://snip.ly/jinfiniti TruDiagnostic: 10% off code "JILL" https://snip.ly/trudiagnostic 0:00 intro 2:30 outro DISCLAIMER: The information provided in this video is for general informational purposes only and does not constitute professional medical advice, diagnosis, treatment, or services. No doctor-patient relationship is formed through your use of this content. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read or seen in this video. Do not make any changes to your health regimen or diet without first consulting your physician. The use of any information provided in this video is solely at your own risk. Jill Ritchie and LONGEVITYLIFESTYLE LLC disclaim any liability for any decisions you make based on the information provided. For a full list of our terms and conditions, please visit our website at https://jillritchie.com/privacy-policy https://www.youtube-nocookie.com/embed/XvR7Fh2CCts 164 2024-07-15T13:00:35.000Z 2026-10-22T19:32:38.632Z https://longevityharbor.com/de/watch/XvR7Fh2CCts How to take NMN for longevity (women over 50) https://i.ytimg.com/vi/XvR7Fh2CCts/hqdefault.jpg In this video, longevity expert Jill Ritchie explains why she's been taking NMN for over 1 year, and reveals her NAD test results. ACCESS FULL SUPPLEMENT LIST HERE ➡️https://www.jillritchie.com/stack ⬅️ J-Infiniti NAD Test: 10% off code “jillritchie” https://snip.ly/fi9sgx J-Infiniti NMN Powder: 10% off code “jillritchie” https://snip.ly/84s65l ProHealth NMN Capsules https://snip.ly/x55gqs RESEARCH PROCESS Want to know how we do our research and why I'm a longevity expert? https://www.jillritchie.com/process Private coaching (limited seats) https://forms.gle/EvyQ2Tm9KTcHRscz9 Promix protein: 10% off code “jillritchie” https://snip.ly/1q3cko $350 off Eight Sleep pod http://snip.ly/8sleep InsideTracker https://snip.ly/y7sa80 Oura Ring https://snip.ly/kfy0bu SoulCycle x Equinox https://snip.ly/6cimjx Jinfiniti: 10% off code "jillritchie" https://snip.ly/jinfiniti TruDiagnostic: 10% off code "JILL" https://snip.ly/trudiagnostic 0:00 intro 2:30 outro DISCLAIMER: The information provided in this video is for general informational purposes only and does not constitute professional medical advice, diagnosis, treatment, or services. No doctor-patient relationship is formed through your use of this content. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read or seen in this video. Do not make any changes to your health regimen or diet without first consulting your physician. The use of any information provided in this video is solely at your own risk. Jill Ritchie and LONGEVITYLIFESTYLE LLC disclaim any liability for any decisions you make based on the information provided. For a full list of our terms and conditions, please visit our website at https://jillritchie.com/privacy-policy https://www.youtube-nocookie.com/embed/XvR7Fh2CCts 164 2024-07-15T13:00:35.000Z 2026-10-22T19:32:38.632Z https://longevityharbor.com/en/watch/Xvz4hUix6ow Seven everyday foods the video suggests people over 60 eat more often https://i.ytimg.com/vi/Xvz4hUix6ow/hqdefault.jpg The description says the video presents seven everyday foods for people over 60 — eggs, oats, plain yogurt, legumes, berries, nuts and oily fish — and links them to protein, fibre, vitamins and healthy fats for muscles, bones, heart and digestion. It offers general information only, not individual medical or nutrition advice. https://www.youtube-nocookie.com/embed/Xvz4hUix6ow 822 2026-10-08T23:07:23.000Z 2026-10-22T20:55:33.473Z https://longevityharbor.com/de/watch/Xvz4hUix6ow Sieben Alltagslebensmittel, die das Video Menschen ab 60 häufiger empfiehlt https://i.ytimg.com/vi/Xvz4hUix6ow/hqdefault.jpg Laut Beschreibung stellt das Video sieben Alltagslebensmittel für Menschen ab 60 vor – Eier, Haferflocken, Naturjoghurt, Hülsenfrüchte, Beeren, Nüsse und fettreichen Fisch – und nennt Eiweiß, Ballaststoffe, Vitamine und gesunde Fette als relevant für Muskeln, Knochen, Herz und Verdauung. Es dient nur der allgemeinen Information, nicht der individuellen medizinischen oder ernährungsmedizinischen Beratung. https://www.youtube-nocookie.com/embed/Xvz4hUix6ow 822 2026-10-08T23:07:23.000Z 2026-10-22T20:55:33.473Z https://longevityharbor.com/en/watch/Xxrqs90DUnE Aging Cells and Chronic Inflammation — Part 8 https://i.ytimg.com/vi/Xxrqs90DUnE/hqdefault.jpg As we age, some cells enter a state called senescence. They stop dividing — but they do not die. Instead, they continue releasing inflammatory signals that contribute to a process called inflammaging. Senescence itself is not inherently harmful. It helps suppress damaged cells and supports tissue repair. The problem is accumulation over time, combined with reduced immune clearance during aging. This creates a self-reinforcing inflammatory cycle linked to aging biology itself. Research into senolytics, autophagy, and cellular aging is now one of the fastest-growing areas in longevity science — but much of the clinical evidence in humans is still emerging. This is Part 8 of the chronic inflammation series. Keywords inflammaging, senescent cells, SASP, chronic inflammation, aging biology, longevity science, senolytics, fisetin, quercetin, dasatinib, autophagy, cellular senescence, healthy aging, mitochondrial health, DNA repair, anti aging science, women over 40, chronic disease, evidence based longevity, chronic inflammation series https://www.youtube-nocookie.com/embed/Xxrqs90DUnE 126 2026-05-26T18:00:35.000Z 2026-10-22T20:11:51.530Z https://longevityharbor.com/de/watch/Xxrqs90DUnE Aging Cells and Chronic Inflammation — Part 8 https://i.ytimg.com/vi/Xxrqs90DUnE/hqdefault.jpg As we age, some cells enter a state called senescence. They stop dividing — but they do not die. Instead, they continue releasing inflammatory signals that contribute to a process called inflammaging. Senescence itself is not inherently harmful. It helps suppress damaged cells and supports tissue repair. The problem is accumulation over time, combined with reduced immune clearance during aging. This creates a self-reinforcing inflammatory cycle linked to aging biology itself. Research into senolytics, autophagy, and cellular aging is now one of the fastest-growing areas in longevity science — but much of the clinical evidence in humans is still emerging. This is Part 8 of the chronic inflammation series. Keywords inflammaging, senescent cells, SASP, chronic inflammation, aging biology, longevity science, senolytics, fisetin, quercetin, dasatinib, autophagy, cellular senescence, healthy aging, mitochondrial health, DNA repair, anti aging science, women over 40, chronic disease, evidence based longevity, chronic inflammation series https://www.youtube-nocookie.com/embed/Xxrqs90DUnE 126 2026-05-26T18:00:35.000Z 2026-10-22T20:11:51.530Z https://longevityharbor.com/en/watch/XyNfItZ3wA4 Calorie Restriction, Fasting & Low-Protein Diet | Prof Dudley Lamming Ep 1 https://i.ytimg.com/vi/XyNfItZ3wA4/hqdefault.jpg In this video Professor Lamming talks about the results that they have seen with CR and how fasting is an important element of the CR process. Also the benefits from restricting just the protein component of the diet while keeping the calories the same. These include lower fat mass and improved insulin sensitivity. Dr. Dudley Lamming is an Associate Professor at the university of Wisconsin-Madison where his lab discovered that low protein diets promote metabolic health—improving blood sugar control and reducing adiposity—in humans and mice, and has identified dietary branched-chain amino acids as key regulators of these effects. And with that let me start the interview. Lamming Lab home page https://lamminglab.medicine.wisc.edu/ NEW: Renue By Science 10% of all products: https://tinyurl.com/4yrf4tv3 ProHealth All Products 10% Discount: https://www.prohealthlongevity.com/discount/MODERN *********************************************************************** Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation. Audio Copyright Disclaimer Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to legal@wevideo.com. ************************************************************************* If you would like to support our channel, we’d love a coffee…thank you! https://www.buymeacoffee.com/mhealthspan #DrLamming #CR #BCAA https://www.youtube-nocookie.com/embed/XyNfItZ3wA4 670 2022-06-11T14:41:12.000Z 2026-10-22T17:43:38.459Z https://longevityharbor.com/de/watch/XyNfItZ3wA4 Calorie Restriction, Fasting & Low-Protein Diet | Prof Dudley Lamming Ep 1 https://i.ytimg.com/vi/XyNfItZ3wA4/hqdefault.jpg In this video Professor Lamming talks about the results that they have seen with CR and how fasting is an important element of the CR process. Also the benefits from restricting just the protein component of the diet while keeping the calories the same. These include lower fat mass and improved insulin sensitivity. Dr. Dudley Lamming is an Associate Professor at the university of Wisconsin-Madison where his lab discovered that low protein diets promote metabolic health—improving blood sugar control and reducing adiposity—in humans and mice, and has identified dietary branched-chain amino acids as key regulators of these effects. And with that let me start the interview. Lamming Lab home page https://lamminglab.medicine.wisc.edu/ NEW: Renue By Science 10% of all products: https://tinyurl.com/4yrf4tv3 ProHealth All Products 10% Discount: https://www.prohealthlongevity.com/discount/MODERN *********************************************************************** Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation. Audio Copyright Disclaimer Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to legal@wevideo.com. ************************************************************************* If you would like to support our channel, we’d love a coffee…thank you! https://www.buymeacoffee.com/mhealthspan #DrLamming #CR #BCAA https://www.youtube-nocookie.com/embed/XyNfItZ3wA4 670 2022-06-11T14:41:12.000Z 2026-10-22T17:43:38.459Z https://longevityharbor.com/en/watch/Y2yFwjQ7-zI Exosomes Modulating Cell Senescence & Exhaustion - Kotb Abdelmohsen at Longevity Summit Dublin 2024 https://i.ytimg.com/vi/Y2yFwjQ7-zI/hqdefault.jpg Exosomes Modulating Cell Senescence & Exhaustion - Kotb Abdelmohsen at Longevity Summit Dublin 2024 https://www.youtube-nocookie.com/embed/Y2yFwjQ7-zI 1579 2024-07-08T07:43:06.000Z 2026-10-22T19:21:23.251Z https://longevityharbor.com/de/watch/Y2yFwjQ7-zI Exosomes Modulating Cell Senescence & Exhaustion - Kotb Abdelmohsen at Longevity Summit Dublin 2024 https://i.ytimg.com/vi/Y2yFwjQ7-zI/hqdefault.jpg Exosomes Modulating Cell Senescence & Exhaustion - Kotb Abdelmohsen at Longevity Summit Dublin 2024 https://www.youtube-nocookie.com/embed/Y2yFwjQ7-zI 1579 2024-07-08T07:43:06.000Z 2026-10-22T19:21:23.251Z https://longevityharbor.com/en/watch/Y357KbUAO9k Should You Take Rapamycin for Anti Aging https://i.ytimg.com/vi/Y357KbUAO9k/hqdefault.jpg 🌟 Should You Take Rapamycin for Anti-Aging and Longevity? 🌟 In this video, we dive deep into the fascinating world of rapamycin, a drug that has gained attention for its potential anti-aging benefits. Join us as we explore the science behind rapamycin, its effects on cellular health, and what the latest research says about its role in longevity. 🔍 What You’ll Learn: - The mechanism of action of rapamycin and how it influences aging. - Current studies and findings on its effects in humans and animals. - Potential benefits and risks associated with taking rapamycin. Is rapamycin the key to a longer, healthier life? Watch now to find out if this controversial compound is worth considering for your anti-aging regimen! 👉 Don’t forget to like, subscribe, and hit the notification bell for more insights on health and longevity! https://www.youtube-nocookie.com/embed/Y357KbUAO9k 398 2025-01-24T10:00:37.000Z 2026-10-22T19:54:22.438Z https://longevityharbor.com/de/watch/Y357KbUAO9k Should You Take Rapamycin for Anti Aging https://i.ytimg.com/vi/Y357KbUAO9k/hqdefault.jpg 🌟 Should You Take Rapamycin for Anti-Aging and Longevity? 🌟 In this video, we dive deep into the fascinating world of rapamycin, a drug that has gained attention for its potential anti-aging benefits. Join us as we explore the science behind rapamycin, its effects on cellular health, and what the latest research says about its role in longevity. 🔍 What You’ll Learn: - The mechanism of action of rapamycin and how it influences aging. - Current studies and findings on its effects in humans and animals. - Potential benefits and risks associated with taking rapamycin. Is rapamycin the key to a longer, healthier life? Watch now to find out if this controversial compound is worth considering for your anti-aging regimen! 👉 Don’t forget to like, subscribe, and hit the notification bell for more insights on health and longevity! https://www.youtube-nocookie.com/embed/Y357KbUAO9k 398 2025-01-24T10:00:37.000Z 2026-10-22T19:54:22.438Z https://longevityharbor.com/en/watch/Y9_tO8MMy2w Best Anti-Aging Diet: Healthy Foods for Youthful Skin from a Facial Plastic Surgeon https://i.ytimg.com/vi/Y9_tO8MMy2w/hqdefault.jpg How to eat healthy and glow from within: Dr. Karam reveals the exact anti-aging meal plan and foods for skin that he and his wife use to build collagen, hydrate skin and create a youthful glow. WATCH MORE FROM DR. KARAM: - What is the BEST Diet for Youthful, Beautiful Skin for life? - http://youtu.be/I9EfPSolsU0 - Hair Loss Treatment that WORKS - How to Regrow Hair from a Doctor's Personal Experience - http://youtu.be/PuRJfY5dVVw 🥦 Read the Karams' full grocery list on the KaramMD Journal: https://karammdskin.com/blogs/expert-advice/my-weekly-grocery-guide-for-glowing-healthy-skin Chapters: 00:00 - Intro: The Secret to Youthful Skin is in Your Kitchen 01:50 - High-Protein Powerhouses for Collagen 04:32 - Protective Foods: Antioxidants & Vitamin C 08:17 - Gut-Healthy Heroes for Skin Clarity 10:01 - Healthy Fats for Supple, Moisturized Skin 11:42 - Combat Inflammation with Omega-3s 12:39 - The Anti-Aging Power of Spices 13:29 - The Key to Long-Term Results 14:09 - How Diet Supports Your Skincare Routine How can you boost your skincare routine? The most powerful strategy for youthful skin might already be in your kitchen. In this video, board-certified facial plastic surgeon Dr. Amir Karam explains why a healthy diet is the foundation for any successful rejuvenation plan. He breaks down the science behind the best foods for skin, revealing his ultimate anti-aging meal plan built on practical, delicious choices. Learn exactly how to eat healthy with healthy meals that support your skin at the cellular level. Dr. Karam even shares the simple daily and weekly system his wife uses for her radiant complexion, making healthy eating for skin achievable for anyone. This guide goes beyond fad diets to give you a true, science-backed grocery list for skin health. We explore specific high protein meals and the benefits of bone broth for collagen synthesis. Discover the most powerful antioxidant foods and Vitamin C foods for skin that protect you from environmental damage. Dr. Karam also details the crucial role of gut he https://www.youtube-nocookie.com/embed/Y9_tO8MMy2w 1006 2025-08-13T13:01:00.000Z 2026-10-22T19:04:44.690Z https://longevityharbor.com/de/watch/Y9_tO8MMy2w Best Anti-Aging Diet: Healthy Foods for Youthful Skin from a Facial Plastic Surgeon https://i.ytimg.com/vi/Y9_tO8MMy2w/hqdefault.jpg How to eat healthy and glow from within: Dr. Karam reveals the exact anti-aging meal plan and foods for skin that he and his wife use to build collagen, hydrate skin and create a youthful glow. WATCH MORE FROM DR. KARAM: - What is the BEST Diet for Youthful, Beautiful Skin for life? - http://youtu.be/I9EfPSolsU0 - Hair Loss Treatment that WORKS - How to Regrow Hair from a Doctor's Personal Experience - http://youtu.be/PuRJfY5dVVw 🥦 Read the Karams' full grocery list on the KaramMD Journal: https://karammdskin.com/blogs/expert-advice/my-weekly-grocery-guide-for-glowing-healthy-skin Chapters: 00:00 - Intro: The Secret to Youthful Skin is in Your Kitchen 01:50 - High-Protein Powerhouses for Collagen 04:32 - Protective Foods: Antioxidants & Vitamin C 08:17 - Gut-Healthy Heroes for Skin Clarity 10:01 - Healthy Fats for Supple, Moisturized Skin 11:42 - Combat Inflammation with Omega-3s 12:39 - The Anti-Aging Power of Spices 13:29 - The Key to Long-Term Results 14:09 - How Diet Supports Your Skincare Routine How can you boost your skincare routine? The most powerful strategy for youthful skin might already be in your kitchen. In this video, board-certified facial plastic surgeon Dr. Amir Karam explains why a healthy diet is the foundation for any successful rejuvenation plan. He breaks down the science behind the best foods for skin, revealing his ultimate anti-aging meal plan built on practical, delicious choices. Learn exactly how to eat healthy with healthy meals that support your skin at the cellular level. Dr. Karam even shares the simple daily and weekly system his wife uses for her radiant complexion, making healthy eating for skin achievable for anyone. This guide goes beyond fad diets to give you a true, science-backed grocery list for skin health. We explore specific high protein meals and the benefits of bone broth for collagen synthesis. Discover the most powerful antioxidant foods and Vitamin C foods for skin that protect you from environmental damage. Dr. Karam also details the crucial role of gut he https://www.youtube-nocookie.com/embed/Y9_tO8MMy2w 1006 2025-08-13T13:01:00.000Z 2026-10-22T19:04:44.690Z https://longevityharbor.com/en/watch/YCva9wQRes8 Video description: resveratrol's $720 million flop and the NMN parallel https://i.ytimg.com/vi/YCva9wQRes8/hqdefault.jpg The description says a pharma giant paid about $720 million for resveratrol firm Sirtris, the headline sirtuin effect was largely a measurement artifact, and the effort was shut down by 2013; it calls this the template NMN and NR follow today. https://www.youtube-nocookie.com/embed/YCva9wQRes8 366 2026-07-22T22:00:13.000Z 2026-10-22T23:23:30.476Z https://longevityharbor.com/de/watch/YCva9wQRes8 Videobeschreibung: Resveratrols 720-Millionen-Dollar-Flop und die NMN-Parallele https://i.ytimg.com/vi/YCva9wQRes8/hqdefault.jpg Laut Beschreibung zahlte ein Pharmakonzern rund 720 Millionen Dollar für die Resveratrol-Firma Sirtris, der Sirtuin-Kerneffekt war weitgehend ein Messartefakt, und 2013 wurde das Vorhaben eingestellt; dies sei die Vorlage, der NMN und NR heute folgen. https://www.youtube-nocookie.com/embed/YCva9wQRes8 366 2026-07-22T22:00:13.000Z 2026-10-22T23:23:30.476Z https://longevityharbor.com/en/watch/YJ5xFGFhTSE Healthy Aging with Mediterranean Nutrition https://i.ytimg.com/vi/YJ5xFGFhTSE/hqdefault.jpg The Mediterranean Way — Mediterranean longevity secrets backed by science. New documentaries every week. Subscribe for evidence-based health content from the world's longest-living communities. 📖 Get the complete Mediterranean Way 90-Day Protocol — 90+ pages — 👉 https://themediterraneanway.netlify.app/?utm_source=youtube&utm_medium=video_description&utm_campaign=tmw_healthy_aging_nuage&utm_content=link_above_fold ⚡ The exact day-by-day system Ikarian, Cretan, and Sardinian elders use to stay lean, sharp, and strong past 100. 🌿 The Mediterranean Way 90-Day Protocol — built for American men and women over 55. ❌ Not another low-fat fad diet. Not supplements. Not religious or political. ✅ Real elders with names + villages. Bread + olive oil daily. ~$14/week at Walmart, Costco, Aldi. 👉 Get it here: https://themediterraneanway.netlify.app/?utm_source=youtube&utm_medium=video_description&utm_campaign=tmw_healthy_aging_nuage&utm_content=link_below_fold 🥣 Healthy aging with Mediterranean nutrition is not the same diet you would hand a 40-year-old. A team of European scientists proved it. In the NU-AGE project (2012–2015), they rewrote the Mediterranean diet for people aged 65 to 79 — and tested it on nearly 1,300 older adults in Italy, England, the Netherlands, Poland and France for one year. They made four edits for the older body: water written into the diet as a food group (1.5 liters a day), two cups of milk or yogurt a day for protein, a daily vitamin D pill, and a ceiling on salt. 🌿 WHAT CHANGES AFTER 65 — AND WHAT THE PLATE DOES ABOUT IT · Thirst fades — older bodies get drier and ask for less, and the old soup-and-beans table doubles as a drink · Muscle needs more protein — at least 1 gram per kilogram a day for older people, and what 20 grams looks like on a Mediterranean table (Greek yogurt, a can of sardines, beans with cheese) · The skin makes less vitamin D — less than half as much as a teenager's skin under the same sun, and why the scientists added a pill instead of trusting the plate · Teeth a https://www.youtube-nocookie.com/embed/YJ5xFGFhTSE 1340 2026-10-10T20:00:12.000Z 2026-10-22T18:43:11.781Z https://longevityharbor.com/de/watch/YJ5xFGFhTSE Healthy Aging with Mediterranean Nutrition https://i.ytimg.com/vi/YJ5xFGFhTSE/hqdefault.jpg The Mediterranean Way — Mediterranean longevity secrets backed by science. New documentaries every week. Subscribe for evidence-based health content from the world's longest-living communities. 📖 Get the complete Mediterranean Way 90-Day Protocol — 90+ pages — 👉 https://themediterraneanway.netlify.app/?utm_source=youtube&utm_medium=video_description&utm_campaign=tmw_healthy_aging_nuage&utm_content=link_above_fold ⚡ The exact day-by-day system Ikarian, Cretan, and Sardinian elders use to stay lean, sharp, and strong past 100. 🌿 The Mediterranean Way 90-Day Protocol — built for American men and women over 55. ❌ Not another low-fat fad diet. Not supplements. Not religious or political. ✅ Real elders with names + villages. Bread + olive oil daily. ~$14/week at Walmart, Costco, Aldi. 👉 Get it here: https://themediterraneanway.netlify.app/?utm_source=youtube&utm_medium=video_description&utm_campaign=tmw_healthy_aging_nuage&utm_content=link_below_fold 🥣 Healthy aging with Mediterranean nutrition is not the same diet you would hand a 40-year-old. A team of European scientists proved it. In the NU-AGE project (2012–2015), they rewrote the Mediterranean diet for people aged 65 to 79 — and tested it on nearly 1,300 older adults in Italy, England, the Netherlands, Poland and France for one year. They made four edits for the older body: water written into the diet as a food group (1.5 liters a day), two cups of milk or yogurt a day for protein, a daily vitamin D pill, and a ceiling on salt. 🌿 WHAT CHANGES AFTER 65 — AND WHAT THE PLATE DOES ABOUT IT · Thirst fades — older bodies get drier and ask for less, and the old soup-and-beans table doubles as a drink · Muscle needs more protein — at least 1 gram per kilogram a day for older people, and what 20 grams looks like on a Mediterranean table (Greek yogurt, a can of sardines, beans with cheese) · The skin makes less vitamin D — less than half as much as a teenager's skin under the same sun, and why the scientists added a pill instead of trusting the plate · Teeth a https://www.youtube-nocookie.com/embed/YJ5xFGFhTSE 1340 2026-10-10T20:00:12.000Z 2026-10-22T18:43:11.781Z https://longevityharbor.com/en/watch/YLAaBnW-MQQ Video description: epigenetic clocks, DNA methylation and biological age claims https://i.ytimg.com/vi/YLAaBnW-MQQ/hqdefault.jpg The description attributes to Ryan Smith, founder of TruDiagnostic, claims that DNA methylation clocks can estimate biological age from a single drop of blood, predict mortality with 92% accuracy within five years and track aging changes in as little as six months. These are creator claims in a video description, not reviewed findings. https://www.youtube-nocookie.com/embed/YLAaBnW-MQQ 1523 2026-02-25T13:54:33.000Z 2026-10-23T02:19:58.160Z https://longevityharbor.com/de/watch/YLAaBnW-MQQ Videobeschreibung: epigenetische Uhren, DNA-Methylierung und Aussagen zum biologischen Alter https://i.ytimg.com/vi/YLAaBnW-MQQ/hqdefault.jpg Die Beschreibung schreibt Ryan Smith, Gründer von TruDiagnostic, Aussagen zu, dass DNA-Methylierungs-Uhren das biologische Alter aus einem einzigen Blutstropfen schätzen, Sterblichkeit innerhalb von fünf Jahren mit 92 % Genauigkeit vorhersagen und Altersveränderungen in nur sechs Monaten verfolgen können. Dies sind Aussagen des Erstellers in einer Videobeschreibung, keine geprüften Ergebnisse. https://www.youtube-nocookie.com/embed/YLAaBnW-MQQ 1523 2026-02-25T13:54:33.000Z 2026-10-23T02:19:58.160Z https://longevityharbor.com/en/watch/YLeWQ5NFJqw Dr Joe Chang video description: biological age clocks, epigenetic tags and the PRISM scanner https://i.ytimg.com/vi/YLeWQ5NFJqw/hqdefault.jpg A video description announces a keynote on biological versus chronological age, aging clocks such as DunedinPACE, epigenetic tags, an optical biomarker scanner called PRISM and planned aging response modulators. No results, numbers or study details are given in the description. https://www.youtube-nocookie.com/embed/YLeWQ5NFJqw 2915 2026-10-16T05:28:02.000Z 2026-10-22T19:30:51.127Z https://longevityharbor.com/de/watch/YLeWQ5NFJqw Video-Beschreibung von Dr. Joe Chang: biologische Altersuhren, epigenetische Marker und der PRISM-Sc https://i.ytimg.com/vi/YLeWQ5NFJqw/hqdefault.jpg Eine Video-Beschreibung kündigt eine Keynote zu biologischem versus chronologischem Alter, Altersuhren wie DunedinPACE, epigenetischen Markern, einem optischen Biomarker-Scanner namens PRISM und geplanten Aging Response Modulatoren an. Ergebnisse, Zahlen oder Studiendetails nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/YLeWQ5NFJqw 2915 2026-10-16T05:28:02.000Z 2026-10-22T19:30:51.127Z https://longevityharbor.com/en/watch/YM1IdENhgp8 Caloric restriction for low AMH: described science, limits and safety cautions https://i.ytimg.com/vi/YM1IdENhgp8/hqdefault.jpg The description presents caloric restriction as an area of research, not a proven way to raise AMH or stop ovarian aging, and warns that severe restriction can harm reproductive function. https://www.youtube-nocookie.com/embed/YM1IdENhgp8 2198 2026-09-10T02:30:07.000Z 2026-10-22T22:19:12.697Z https://longevityharbor.com/de/watch/YM1IdENhgp8 Kalorienrestriktion bei niedrigem AMH: beschriebene Wissenschaft, Grenzen und Sicherheitshinweise https://i.ytimg.com/vi/YM1IdENhgp8/hqdefault.jpg Die Beschreibung stellt Kalorienrestriktion als Forschungsfeld dar, nicht als belegten Weg, AMH zu erhöhen oder das Eierstockaltern zu stoppen, und warnt, dass starke Restriktion die Fortpflanzungsfunktion beeinträchtigen kann. https://www.youtube-nocookie.com/embed/YM1IdENhgp8 2198 2026-09-10T02:30:07.000Z 2026-10-22T22:19:12.697Z https://longevityharbor.com/en/watch/YPGBQPqvwDg Sugar, Protein & Aging: Two Metabolism PhDs on Surprising New Science https://i.ytimg.com/vi/YPGBQPqvwDg/hqdefault.jpg In this thought-provoking conversation with Dr. Nic Verhoeven, PhD, creator of the Physionic channel, we delve into the controversial topic of the “sugar diet.” Join us as we break down the science behind this unexpected diet trend, discuss the roles of the hormone FGF-21, and what new research published in top journals (Nature Metabolism and Cell Metabolism) has to teach us well beyond this diet fad. We tackle the physiology of the sugar diet, the mechanisms behind protein restriction, and share surprising findings that might challenge conventional wisdom. Don’t Miss: Newsletter on The Sugar Diet, Protein Restriction and Longevity: https://open.substack.com/pub/staycuriousmetabolism/p/the-sugar-diet-protein-restriction?r=40ekz2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true Our Prior Conservation on Seed Oils: https://youtu.be/VDJGCw-enhI My Coverage Solo Coverage on the Sugar Diet: https://youtu.be/IAc_7r_hVI8 Chapters: 00:00 – Intro: Welcome Back Dr Nic Verhoeven, PhD 00:39 – What Is the Sugar Diet? Why It’s Gaining Attention 02:00 – FGF-21: The Metabolism Boosting Hormone at the Centre of the Story 04:30 – How Eating Less Protein Might Burn More Energy 12:00 – Can FGF-21 Help Treat Obesity? 15:39 – FGF 21, Protein, and Muscle Mass in Older Adults 23:35 – FGF-21: Metabolism, Longevity & Lifespan Extension 27:57 – Longevity vs. Performance: Can You Have Both? 33:27 – Hot Takes: Methylene Blue, Coffee, and Chlorogenic Acid #SugarDiet #FGF21 #FatLoss #MetabolicHealth #LongevityScience #ProteinRestriction #HealthyAging #HormonalHealth #NutritionResearch #DietScience #ObesityResearch #MuscleHealth #LifespanExtension #AntiAging #MitochondrialHealth #ScienceBasedNutrition #OptimizeYourHealth #Biohacking #EvidenceBasedMedicine #PersonalizedNutrition #HealthyMetabolism #FunctionalHealth #Healthspan #WellnessScience #NutritionPodcast #NutritionDebate #NickNorwitz #Physionic #HealthOptimization #ModernNutrition #ScientificNutrition #LongevityTips #WellnessJourney #BiohackYourHealth #LiveL https://www.youtube-nocookie.com/embed/YPGBQPqvwDg 2218 2025-08-08T11:01:07.000Z 2026-10-22T19:04:44.790Z https://longevityharbor.com/de/watch/YPGBQPqvwDg Sugar, Protein & Aging: Two Metabolism PhDs on Surprising New Science https://i.ytimg.com/vi/YPGBQPqvwDg/hqdefault.jpg In this thought-provoking conversation with Dr. Nic Verhoeven, PhD, creator of the Physionic channel, we delve into the controversial topic of the “sugar diet.” Join us as we break down the science behind this unexpected diet trend, discuss the roles of the hormone FGF-21, and what new research published in top journals (Nature Metabolism and Cell Metabolism) has to teach us well beyond this diet fad. We tackle the physiology of the sugar diet, the mechanisms behind protein restriction, and share surprising findings that might challenge conventional wisdom. Don’t Miss: Newsletter on The Sugar Diet, Protein Restriction and Longevity: https://open.substack.com/pub/staycuriousmetabolism/p/the-sugar-diet-protein-restriction?r=40ekz2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true Our Prior Conservation on Seed Oils: https://youtu.be/VDJGCw-enhI My Coverage Solo Coverage on the Sugar Diet: https://youtu.be/IAc_7r_hVI8 Chapters: 00:00 – Intro: Welcome Back Dr Nic Verhoeven, PhD 00:39 – What Is the Sugar Diet? Why It’s Gaining Attention 02:00 – FGF-21: The Metabolism Boosting Hormone at the Centre of the Story 04:30 – How Eating Less Protein Might Burn More Energy 12:00 – Can FGF-21 Help Treat Obesity? 15:39 – FGF 21, Protein, and Muscle Mass in Older Adults 23:35 – FGF-21: Metabolism, Longevity & Lifespan Extension 27:57 – Longevity vs. Performance: Can You Have Both? 33:27 – Hot Takes: Methylene Blue, Coffee, and Chlorogenic Acid #SugarDiet #FGF21 #FatLoss #MetabolicHealth #LongevityScience #ProteinRestriction #HealthyAging #HormonalHealth #NutritionResearch #DietScience #ObesityResearch #MuscleHealth #LifespanExtension #AntiAging #MitochondrialHealth #ScienceBasedNutrition #OptimizeYourHealth #Biohacking #EvidenceBasedMedicine #PersonalizedNutrition #HealthyMetabolism #FunctionalHealth #Healthspan #WellnessScience #NutritionPodcast #NutritionDebate #NickNorwitz #Physionic #HealthOptimization #ModernNutrition #ScientificNutrition #LongevityTips #WellnessJourney #BiohackYourHealth #LiveL https://www.youtube-nocookie.com/embed/YPGBQPqvwDg 2218 2025-08-08T11:01:07.000Z 2026-10-22T19:04:44.790Z https://longevityharbor.com/en/watch/YQagUsX6mcU Podcast description: muscle, aging and longevity with Schoenfeld and Aragon https://i.ytimg.com/vi/YQagUsX6mcU/hqdefault.jpg The description says this conversation with Brad Schoenfeld and Alan Aragon covers protein targets, body recomposition, resistance training and muscle maintenance for aging well; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/YQagUsX6mcU 12610 2026-02-23T14:01:02.000Z 2026-10-23T02:25:39.860Z https://longevityharbor.com/de/watch/YQagUsX6mcU Podcast-Beschreibung: Muskel, Altern und Langlebigkeit mit Schoenfeld und Aragon https://i.ytimg.com/vi/YQagUsX6mcU/hqdefault.jpg Laut Beschreibung behandelt dieses Gespräch mit Brad Schoenfeld und Alan Aragon Proteinziele, Körperrekomposition, Krafttraining und Muskelerhalt für gesundes Altern; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/YQagUsX6mcU 12610 2026-02-23T14:01:02.000Z 2026-10-23T02:25:39.860Z https://longevityharbor.com/en/watch/YWVQRDmgnSA Video description: cellular senescence, senolytics and a herb extract in cell culture https://i.ytimg.com/vi/YWVQRDmgnSA/hqdefault.jpg The description says skincare research is moving toward targeting cellular aging, describes senescent cells and senolytics, and reports that in cell culture a Serica herb extract cleared about 70% of senescent cells. https://www.youtube-nocookie.com/embed/YWVQRDmgnSA 515 2026-09-28T04:27:32.000Z 2026-10-22T21:41:34.505Z https://longevityharbor.com/de/watch/YWVQRDmgnSA Videobeschreibung: Zelluläre Seneszenz, Senolytika und ein Kräuterextrakt in Zellkultur https://i.ytimg.com/vi/YWVQRDmgnSA/hqdefault.jpg Die Beschreibung sagt, Hautpflegeforschung bewege sich hin zum zellulären Altern, erklärt seneszente Zellen und Senolytika und berichtet, dass ein Serica-Kräuterextrakt in Zellkultur etwa 70 % der seneszenten Zellen beseitigte. https://www.youtube-nocookie.com/embed/YWVQRDmgnSA 515 2026-09-28T04:27:32.000Z 2026-10-22T21:41:34.505Z https://longevityharbor.com/en/watch/Y_d2Gg4DD9k Video description: dog epigenetic clocks and biological age testing https://i.ytimg.com/vi/Y_d2Gg4DD9k/hqdefault.jpg The description says this episode explores how epigenetics and biological age testing could change preventive pet health, using small DNA changes to estimate how fast a dog is aging and possible disease risk before symptoms appear. https://www.youtube-nocookie.com/embed/Y_d2Gg4DD9k 2482 2026-03-25T10:00:56.000Z 2026-10-23T01:52:18.677Z https://longevityharbor.com/de/watch/Y_d2Gg4DD9k Videobeschreibung: epigenetische Hundeuhren und biologisches Alters-Testing https://i.ytimg.com/vi/Y_d2Gg4DD9k/hqdefault.jpg Laut Beschreibung erkundet diese Episode, wie Epigenetik und Tests des biologischen Alters die vorbeugende Tiergesundheit verändern könnten: kleine DNA-Veränderungen sollen schätzen, wie schnell ein Hund altert und ob Krankheitsrisiken vor Symptomen bestehen. https://www.youtube-nocookie.com/embed/Y_d2Gg4DD9k 2482 2026-03-25T10:00:56.000Z 2026-10-23T01:52:18.677Z https://longevityharbor.com/en/watch/YaGompkqkvE Loneliness, Depression and Stress Linked to Faster Epigenetic Aging in Adults https://i.ytimg.com/vi/YaGompkqkvE/hqdefault.jpg A pooled analysis of 22 studies of adults from midlife onward found modest associations between loneliness, depression or psychosocial stress and faster biological aging measured by epigenetic clocks in blood. These are associations, not causes, and no eligible study examined anxiety. https://www.youtube-nocookie.com/embed/YaGompkqkvE 3893 2026-10-17T10:23:05.000Z 2026-10-22T19:39:10.454Z https://longevityharbor.com/de/watch/YaGompkqkvE Einsamkeit, Depression und Stress mit schnellerer epigenetischer Alterung bei Erwachsenen verbunden https://i.ytimg.com/vi/YaGompkqkvE/hqdefault.jpg Eine gepoolte Analyse von 22 Studien mit Erwachsenen ab dem mittleren Lebensalter fand bescheidene Zusammenhänge zwischen Einsamkeit, Depression oder psychosozialem Stress und schnellerer biologischer Alterung, gemessen mit epigenetischen Uhren im Blut. Dies sind Assoziationen, keine Ursachen, und keine geeignete Studie untersuchte Angst. https://www.youtube-nocookie.com/embed/YaGompkqkvE 3893 2026-10-17T10:23:05.000Z 2026-10-22T19:39:10.454Z https://longevityharbor.com/en/watch/Yat1hI5Eu3I Cellular Senescence & Senolytics https://i.ytimg.com/vi/Yat1hI5Eu3I/hqdefault.jpg #breakthroughjuniorchallenge https://www.youtube-nocookie.com/embed/Yat1hI5Eu3I 115 2026-09-16T02:30:28.000Z 2026-10-23T02:56:02.579Z https://longevityharbor.com/de/watch/Yat1hI5Eu3I Cellular Senescence & Senolytics https://i.ytimg.com/vi/Yat1hI5Eu3I/hqdefault.jpg #breakthroughjuniorchallenge https://www.youtube-nocookie.com/embed/Yat1hI5Eu3I 115 2026-09-16T02:30:28.000Z 2026-10-23T02:56:02.579Z https://longevityharbor.com/en/watch/YciZxa88pH8 Video description: fasting mistakes for people over 60, inspired by Jason Fung https://i.ytimg.com/vi/YciZxa88pH8/hqdefault.jpg The description says the video lists five fasting mistakes for seniors, including ignoring insulin resistance, and claims these can raise blood sugar and slow metabolism; the video itself was not reviewed. https://www.youtube-nocookie.com/embed/YciZxa88pH8 715 2026-08-09T20:00:58.000Z 2026-10-22T23:06:55.885Z https://longevityharbor.com/de/watch/YciZxa88pH8 Videobeschreibung: Fastenfehler für Menschen über 60, inspiriert von Jason Fung https://i.ytimg.com/vi/YciZxa88pH8/hqdefault.jpg Die Beschreibung nennt fünf Fastenfehler für Senioren, darunter das Ignorieren von Insulinresistenz, und behauptet, diese könnten den Blutzucker erhöhen und den Stoffwechsel verlangsamen; das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/YciZxa88pH8 715 2026-08-09T20:00:58.000Z 2026-10-22T23:06:55.885Z https://longevityharbor.com/en/watch/YeuL-P6jBPA Can NMN Help with ME/CFS? https://i.ytimg.com/vi/YeuL-P6jBPA/hqdefault.jpg NMN may have potential as part of a comprehensive strategy for people suffering from ME/CFS. Some studies show reduced NAD+ levels in patients, but everyone is different and expectations need to be tempered. If you want to try NMN, here's a link to ours; https://longevityformulas.co.uk/products/nmn-supplement https://www.youtube-nocookie.com/embed/YeuL-P6jBPA 178 2025-10-22T10:56:49.000Z 2026-10-22T19:04:42.908Z https://longevityharbor.com/de/watch/YeuL-P6jBPA Can NMN Help with ME/CFS? https://i.ytimg.com/vi/YeuL-P6jBPA/hqdefault.jpg NMN may have potential as part of a comprehensive strategy for people suffering from ME/CFS. Some studies show reduced NAD+ levels in patients, but everyone is different and expectations need to be tempered. If you want to try NMN, here's a link to ours; https://longevityformulas.co.uk/products/nmn-supplement https://www.youtube-nocookie.com/embed/YeuL-P6jBPA 178 2025-10-22T10:56:49.000Z 2026-10-22T19:04:42.908Z https://longevityharbor.com/en/watch/YhA_x8OLJr8 Aging, Geroscience and Longevity Symposium – Session two https://i.ytimg.com/vi/YhA_x8OLJr8/hqdefault.jpg eLife Senior Editors Jess Tyler and Matt Kaeberlein chaired this half-day online symposium, where authors whose papers have been accepted for our upcoming Aging, Geroscience and Longevity Special Issue presented the key findings. These accepted authors presented their research through live and pre-recorded presentations. Session two includes the following speakers: 00:00:45 Mounir El Maï – Institute for Research on Cancer and Aging of Nice (IRCAN), INSERM, France 00:17:14 Morgan Levine – Yale School of Medicine, United States 00:35:49 Dudley Lamming – University of Wisconsin-Madison, United States 00:57:24 Amanda Kowalczyk – Carnegie Mellon University – University of Pittsburgh Joint PhD Program in Computational Biology, United States https://www.youtube-nocookie.com/embed/YhA_x8OLJr8 4496 2020-12-16T15:44:29.000Z 2026-10-22T17:43:40.182Z https://longevityharbor.com/de/watch/YhA_x8OLJr8 Aging, Geroscience and Longevity Symposium – Session two https://i.ytimg.com/vi/YhA_x8OLJr8/hqdefault.jpg eLife Senior Editors Jess Tyler and Matt Kaeberlein chaired this half-day online symposium, where authors whose papers have been accepted for our upcoming Aging, Geroscience and Longevity Special Issue presented the key findings. These accepted authors presented their research through live and pre-recorded presentations. Session two includes the following speakers: 00:00:45 Mounir El Maï – Institute for Research on Cancer and Aging of Nice (IRCAN), INSERM, France 00:17:14 Morgan Levine – Yale School of Medicine, United States 00:35:49 Dudley Lamming – University of Wisconsin-Madison, United States 00:57:24 Amanda Kowalczyk – Carnegie Mellon University – University of Pittsburgh Joint PhD Program in Computational Biology, United States https://www.youtube-nocookie.com/embed/YhA_x8OLJr8 4496 2020-12-16T15:44:29.000Z 2026-10-22T17:43:40.182Z https://longevityharbor.com/en/watch/YjY6yRSkIk0 Longevity discussion: 12 hallmarks, Novos Core trials, biological age clocks https://i.ytimg.com/vi/YjY6yRSkIk0/hqdefault.jpg In this video description, Chris Mirabile links his brain tumor at 16 to his focus on prevention and describes the 12 hallmarks of aging framework behind the supplement Novos Core, plus reported trial results, biological age tests and his personal routine. https://www.youtube-nocookie.com/embed/YjY6yRSkIk0 5206 2026-02-24T12:01:03.000Z 2026-10-23T02:20:34.069Z https://longevityharbor.com/de/watch/YjY6yRSkIk0 Longevity-Gespräch: 12 Hallmarks, Novos-Core-Studien, biologische Altersuhren https://i.ytimg.com/vi/YjY6yRSkIk0/hqdefault.jpg In dieser Videobeschreibung verbindet Chris Mirabile seinen Hirntumor mit 16 mit seinem Fokus auf Vorbeugung und beschreibt das Rahmenwerk der 12 Hallmarks des Alterns hinter dem Supplement Novos Core, dazu berichtete Studienergebnisse, biologische Alterstests und seine persönliche Routine. https://www.youtube-nocookie.com/embed/YjY6yRSkIk0 5206 2026-02-24T12:01:03.000Z 2026-10-23T02:20:34.069Z https://longevityharbor.com/en/watch/Ykvkg2Jz3X8 Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair https://i.ytimg.com/vi/Ykvkg2Jz3X8/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this ⁠Huberman Lab Essentials⁠ episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, regular exercise and NAD⁺-boosting compounds like NMN, can activate the body's natural longevity pathways. This discussion highlights how lifestyle choices profoundly influence the aging process and may even slow or reverse key aspects of biological aging. Episode show notes: https://go.hubermanlab.com/MW6SYCf Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/n9IxomBusuw Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S *Follow Huberman Lab* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Timestamps* 00:00:00 David Sinclair 00:00:20 Longevity, Anti-Aging, Aging as a Disease 00:02:27 Causes of Aging; Epigenome & Genes 00:04:53 CD & Scratches Analogy, DNA, Silencing & Expressing Genes 00:06:44 Physical Appearance & Aging 00:07:36 Childhood Development & Aging, Horvath Clock, Accelerate Aging 00:10:13 Rates of Puberty & Aging, Growth Hormone 00:11:20 Body Size & Longevity; Epigenetics 00:11:50 Fasting, Calorie Restriction & Longevity, Sirtuins, Insulin & Glucose 00:15:14 Tool: Skip a Meal 00:15:50 Longer Fasts & Autophagy, “Deep Cleanse”; Fluids, Electrolytes 00:17:28 Sirtuins, Glucose, mTOR & Fasting; Leucine, To https://www.youtube-nocookie.com/embed/Ykvkg2Jz3X8 2040 2025-10-30T12:01:11.000Z 2026-10-22T18:43:09.833Z https://longevityharbor.com/de/watch/Ykvkg2Jz3X8 Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair https://i.ytimg.com/vi/Ykvkg2Jz3X8/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this ⁠Huberman Lab Essentials⁠ episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, regular exercise and NAD⁺-boosting compounds like NMN, can activate the body's natural longevity pathways. This discussion highlights how lifestyle choices profoundly influence the aging process and may even slow or reverse key aspects of biological aging. Episode show notes: https://go.hubermanlab.com/MW6SYCf Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/n9IxomBusuw Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S *Follow Huberman Lab* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Timestamps* 00:00:00 David Sinclair 00:00:20 Longevity, Anti-Aging, Aging as a Disease 00:02:27 Causes of Aging; Epigenome & Genes 00:04:53 CD & Scratches Analogy, DNA, Silencing & Expressing Genes 00:06:44 Physical Appearance & Aging 00:07:36 Childhood Development & Aging, Horvath Clock, Accelerate Aging 00:10:13 Rates of Puberty & Aging, Growth Hormone 00:11:20 Body Size & Longevity; Epigenetics 00:11:50 Fasting, Calorie Restriction & Longevity, Sirtuins, Insulin & Glucose 00:15:14 Tool: Skip a Meal 00:15:50 Longer Fasts & Autophagy, “Deep Cleanse”; Fluids, Electrolytes 00:17:28 Sirtuins, Glucose, mTOR & Fasting; Leucine, To https://www.youtube-nocookie.com/embed/Ykvkg2Jz3X8 2040 2025-10-30T12:01:11.000Z 2026-10-22T18:43:09.833Z https://longevityharbor.com/en/watch/Ym5FkuhXQWY Medicine 4.0: Optimizing Health through Longevity Science | Dr. Matt Kaeberlein https://i.ytimg.com/vi/Ym5FkuhXQWY/hqdefault.jpg In this talk, Dr. Matt Kaeberlein, Optispan, Washington, USA, discusses how age is the greatest risk factor for nearly every major cause of death and disability in developed nations. Yet, traditional biomedical research, drug development, and clinical practice have generally focused on waiting until people are sick and treating individual diseases one at a time. Attempts to cure age-related diseases have proven unsuccessful at the population level, and the impact of disease-first approaches continues to be incremental. He sheds light on recent advances in understanding the mechanisms linking biological aging to disease, or geroscience, which have identified interventions that directly target the molecular hallmarks of aging. Unlike disease-specific approaches, such interventions have the potential to delay or prevent multiple diseases of aging simultaneously, thereby greatly enhancing healthspan and perhaps lifespan for many individuals. Dr. Kaeberlein provides an overview of Medicine 4.0, which he believes will become the paradigm for the practice of both veterinary and human medicine in the 21st century. Medicine 4.0 will combine science-based proactive healthcare, cutting-edge geroscience discoveries, and novel artificial intelligence tools to provide comprehensive support for personalized health optimization. For more such discussions, check out Biopeak Live, Longevity India Podcast: https://www.youtube.com/playlist?list=PLHTK7cOaLiYvUZr_Tl5NsSA_hT0uSkmRe 🔔 Subscribe and stay tuned! More: 🌐Longevity India: https://linktr.ee/longevity.india https://www.youtube-nocookie.com/embed/Ym5FkuhXQWY 1538 2025-10-28T05:00:42.000Z 2026-10-22T19:04:38.517Z https://longevityharbor.com/de/watch/Ym5FkuhXQWY Medicine 4.0: Optimizing Health through Longevity Science | Dr. Matt Kaeberlein https://i.ytimg.com/vi/Ym5FkuhXQWY/hqdefault.jpg In this talk, Dr. Matt Kaeberlein, Optispan, Washington, USA, discusses how age is the greatest risk factor for nearly every major cause of death and disability in developed nations. Yet, traditional biomedical research, drug development, and clinical practice have generally focused on waiting until people are sick and treating individual diseases one at a time. Attempts to cure age-related diseases have proven unsuccessful at the population level, and the impact of disease-first approaches continues to be incremental. He sheds light on recent advances in understanding the mechanisms linking biological aging to disease, or geroscience, which have identified interventions that directly target the molecular hallmarks of aging. Unlike disease-specific approaches, such interventions have the potential to delay or prevent multiple diseases of aging simultaneously, thereby greatly enhancing healthspan and perhaps lifespan for many individuals. Dr. Kaeberlein provides an overview of Medicine 4.0, which he believes will become the paradigm for the practice of both veterinary and human medicine in the 21st century. Medicine 4.0 will combine science-based proactive healthcare, cutting-edge geroscience discoveries, and novel artificial intelligence tools to provide comprehensive support for personalized health optimization. For more such discussions, check out Biopeak Live, Longevity India Podcast: https://www.youtube.com/playlist?list=PLHTK7cOaLiYvUZr_Tl5NsSA_hT0uSkmRe 🔔 Subscribe and stay tuned! More: 🌐Longevity India: https://linktr.ee/longevity.india https://www.youtube-nocookie.com/embed/Ym5FkuhXQWY 1538 2025-10-28T05:00:42.000Z 2026-10-22T19:04:38.517Z https://longevityharbor.com/en/watch/YpXxiMt9Fpo Matt Kaeberlein - Aging, mTOR, Epigenetic Clocks, and more! @optispan https://i.ytimg.com/vi/YpXxiMt9Fpo/hqdefault.jpg What if aging isn’t just inevitable—but modifiable? In this episode of Longevity Roadmap, Dr. Matt Kaeberlein breaks down the science of biological aging, with a focus on mTOR, epigenetics, and the hallmarks of aging like cellular senescence, mitochondrial dysfunction, and epigenetic drift. He explores the role of genetics vs. environment, the promise and pitfalls of metformin, NAD boosters, and senolytics, and why interventions like rapamycin and caloric restriction may extend health span. From the limitations of biological age tests to the importance of lean muscle mass, this conversation is a masterclass in evidence-based longevity research. Watch the full episode to understand the mechanisms of aging—and what current science says about slowing them down. Learn more about Dr. Matt Kaeberlein and Optisan: https://www.optispan.life/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/ - 🎁 Special offers from our podcast guests: 🧬 Telo-Vital (Dr. Bill Andrews) – 55% Off: Get your first bottle for $49 with free shipping to US, UK, Canada, Mexico, Australia, New Zealand & 20+ European countries. Link: longevityroadmap.thegoodinside.com/special-offer-telo-vital-lp 🌱 Stemregen (Dr. Christian Drapeau) – 15% Off: Use code LONGEVITYROADMAP (one-time purchase, new customers only, one use per customer, cannot combine discounts). Link: stemregen.co/collections/all 🐟 Fatty15 (Dr. Stephanie Venn-Watson) – 15% Off: Save on your first order. Link: fatty15.com/LONGEVITYROADMAP 💧 OneSkin (Dr. Carolina Reis Oliveira) – 15% Off: Use code BUCK at checkout if the discount is not automatically applied. Link: oneskin.co/BUCK 🧠 Nuchido (Dr. Nichola Conlon) – 20% Off: Use code SAPIO20 at checkout. Link: nuchido.com ⚡ AX3 (David M. Watumull) – 20% Off: Use code ROADMAP20 if the discount is not automatically applied. Link: glnk.io/5w7jn/longev https://www.youtube-nocookie.com/embed/YpXxiMt9Fpo 4005 2025-04-15T15:14:59.000Z 2026-10-22T19:04:37.650Z https://longevityharbor.com/de/watch/YpXxiMt9Fpo Matt Kaeberlein - Aging, mTOR, Epigenetic Clocks, and more! @optispan https://i.ytimg.com/vi/YpXxiMt9Fpo/hqdefault.jpg What if aging isn’t just inevitable—but modifiable? In this episode of Longevity Roadmap, Dr. Matt Kaeberlein breaks down the science of biological aging, with a focus on mTOR, epigenetics, and the hallmarks of aging like cellular senescence, mitochondrial dysfunction, and epigenetic drift. He explores the role of genetics vs. environment, the promise and pitfalls of metformin, NAD boosters, and senolytics, and why interventions like rapamycin and caloric restriction may extend health span. From the limitations of biological age tests to the importance of lean muscle mass, this conversation is a masterclass in evidence-based longevity research. Watch the full episode to understand the mechanisms of aging—and what current science says about slowing them down. Learn more about Dr. Matt Kaeberlein and Optisan: https://www.optispan.life/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/ - 🎁 Special offers from our podcast guests: 🧬 Telo-Vital (Dr. Bill Andrews) – 55% Off: Get your first bottle for $49 with free shipping to US, UK, Canada, Mexico, Australia, New Zealand & 20+ European countries. Link: longevityroadmap.thegoodinside.com/special-offer-telo-vital-lp 🌱 Stemregen (Dr. Christian Drapeau) – 15% Off: Use code LONGEVITYROADMAP (one-time purchase, new customers only, one use per customer, cannot combine discounts). Link: stemregen.co/collections/all 🐟 Fatty15 (Dr. Stephanie Venn-Watson) – 15% Off: Save on your first order. Link: fatty15.com/LONGEVITYROADMAP 💧 OneSkin (Dr. Carolina Reis Oliveira) – 15% Off: Use code BUCK at checkout if the discount is not automatically applied. Link: oneskin.co/BUCK 🧠 Nuchido (Dr. Nichola Conlon) – 20% Off: Use code SAPIO20 at checkout. Link: nuchido.com ⚡ AX3 (David M. Watumull) – 20% Off: Use code ROADMAP20 if the discount is not automatically applied. Link: glnk.io/5w7jn/longev https://www.youtube-nocookie.com/embed/YpXxiMt9Fpo 4005 2025-04-15T15:14:59.000Z 2026-10-22T19:04:37.650Z https://longevityharbor.com/en/watch/YpzRnvEx_rk NAD+ Supplements & Aging: What Actually Works | Dr. Nichola Conlon https://i.ytimg.com/vi/YpzRnvEx_rk/hqdefault.jpg Molecular biologist Dr. Nichola Conlon explains why NAD+ declines with age and compares the main ways people try to raise it, from NMN and NR to IV drips and lifestyle. The 5 daily habits neuroscientists use to protect their brain - free guide: https://longevity-and-lifestyle.com/brain?utm_source=youtube&utm_medium=description&utm_campaign=brain_blueprint&utm_content=B Guest: Dr. Nichola Conlon - company Instagram @nuchidolabs, YouTube @nuchido2094, TikTok @nuchido Are you ready to uncover the science behind cellular aging and the secrets to potentially slowing or reversing the aging process? Join us in today's episode featuring the renowned Dr. Nichola Conlon, a leading expert in cellular aging and the CEO of Nuchido. With a background in drug development and a strong focus on addressing the 12 hallmarks of aging, Dr. Conlon has dedicated her work to understanding the impact of NAD levels on the aging process. In this episode, we delve into the crucial functions of NAD in cellular health, the effects of NAD decline on the body, and the potential of natural molecules for longevity. Join us as we explore the latest insights into aging science and the innovative research that could revolutionize our understanding of aging in the future. Tune in and discover how lifestyle changes and targeted supplements may hold the key to aging well. Please enjoy! Sponsor: Nuchido TIME+ next generation NAD+ supplement: https://nuchido.com/ for 10% off use code LONGEVITY at checkout. 👉 Follow Claudia von Boeselager On: Instagram: https://www.instagram.com/longevityandlifestyle LinkedIn: https://www.linkedin.com/in/claudia-von-boeselager 👉 Ready to level up your life? 🚀 Discover my 10 Hacks to Improve Your Life & Longevity Playbook! Smarter, healthier, and more exciting living starts here. Grab your free copy now at longevity-and-lifestyle.com/freebie! Past guests on The Longevity & Lifestyle Podcast include Dr. David Perlmutter, Dr. Amy Killen, Sergey Young, Dr. Molly Maloof, Dr. Dale Bredesen, Shawn Wells, Dr. Dave Rabi https://www.youtube-nocookie.com/embed/YpzRnvEx_rk 3431 2024-05-22T09:00:33.000Z 2026-10-22T19:04:37.429Z https://longevityharbor.com/de/watch/YpzRnvEx_rk NAD+ Supplements & Aging: What Actually Works | Dr. Nichola Conlon https://i.ytimg.com/vi/YpzRnvEx_rk/hqdefault.jpg Molecular biologist Dr. Nichola Conlon explains why NAD+ declines with age and compares the main ways people try to raise it, from NMN and NR to IV drips and lifestyle. The 5 daily habits neuroscientists use to protect their brain - free guide: https://longevity-and-lifestyle.com/brain?utm_source=youtube&utm_medium=description&utm_campaign=brain_blueprint&utm_content=B Guest: Dr. Nichola Conlon - company Instagram @nuchidolabs, YouTube @nuchido2094, TikTok @nuchido Are you ready to uncover the science behind cellular aging and the secrets to potentially slowing or reversing the aging process? Join us in today's episode featuring the renowned Dr. Nichola Conlon, a leading expert in cellular aging and the CEO of Nuchido. With a background in drug development and a strong focus on addressing the 12 hallmarks of aging, Dr. Conlon has dedicated her work to understanding the impact of NAD levels on the aging process. In this episode, we delve into the crucial functions of NAD in cellular health, the effects of NAD decline on the body, and the potential of natural molecules for longevity. Join us as we explore the latest insights into aging science and the innovative research that could revolutionize our understanding of aging in the future. Tune in and discover how lifestyle changes and targeted supplements may hold the key to aging well. Please enjoy! Sponsor: Nuchido TIME+ next generation NAD+ supplement: https://nuchido.com/ for 10% off use code LONGEVITY at checkout. 👉 Follow Claudia von Boeselager On: Instagram: https://www.instagram.com/longevityandlifestyle LinkedIn: https://www.linkedin.com/in/claudia-von-boeselager 👉 Ready to level up your life? 🚀 Discover my 10 Hacks to Improve Your Life & Longevity Playbook! Smarter, healthier, and more exciting living starts here. Grab your free copy now at longevity-and-lifestyle.com/freebie! Past guests on The Longevity & Lifestyle Podcast include Dr. David Perlmutter, Dr. Amy Killen, Sergey Young, Dr. Molly Maloof, Dr. Dale Bredesen, Shawn Wells, Dr. Dave Rabi https://www.youtube-nocookie.com/embed/YpzRnvEx_rk 3431 2024-05-22T09:00:33.000Z 2026-10-22T19:04:37.429Z https://longevityharbor.com/en/watch/YxdJyvkat3w NAD Wars: NMN vs NR in the Aging Battle https://i.ytimg.com/vi/YxdJyvkat3w/hqdefault.jpg In this episode of Daily Value, we look inside the NAD+ wars - breaking down the science, the hype, and the controversy surrounding Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN). These two molecules have been promoted as keys to longevity, but the story is far more complex. We’ll look at the biochemistry of NAD+ metabolism, compare what the research really says about NR and NMN, and dig into the regulatory drama that’s shaped their (NMN’s) availability. Most importantly, we’'ll look at a bigger-picture strategy for restoring NAD+, one that goes beyond precursors alone. PMID: 35134387 PMID: 39026037 doi:10.1002/fft2.511 00:00 the NAD Wars 01:02 Understanding NAD+ and Its Importance 04:14 Challenges and Regulatory Issues with NMN and NR 05:44 Clinical Research and Safety Profiles 07:13 Complexities in Boosting NAD+ Levels 09:04 Multi-Targeted Strategies for NAD+ Restoration 13:25 Conclusion: Embracing Complexity in Aging https://www.instagram.com/dr.williamwallace/ https://www.facebook.com/williamwallacePhD https://twitter.com/williamwallace https://www.linkedin.com/in/drwilliamwallace/ https://www.youtube-nocookie.com/embed/YxdJyvkat3w 829 2025-05-23T11:02:42.000Z 2026-10-22T20:11:48.359Z https://longevityharbor.com/de/watch/YxdJyvkat3w NAD Wars: NMN vs NR in the Aging Battle https://i.ytimg.com/vi/YxdJyvkat3w/hqdefault.jpg In this episode of Daily Value, we look inside the NAD+ wars - breaking down the science, the hype, and the controversy surrounding Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN). These two molecules have been promoted as keys to longevity, but the story is far more complex. We’ll look at the biochemistry of NAD+ metabolism, compare what the research really says about NR and NMN, and dig into the regulatory drama that’s shaped their (NMN’s) availability. Most importantly, we’'ll look at a bigger-picture strategy for restoring NAD+, one that goes beyond precursors alone. PMID: 35134387 PMID: 39026037 doi:10.1002/fft2.511 00:00 the NAD Wars 01:02 Understanding NAD+ and Its Importance 04:14 Challenges and Regulatory Issues with NMN and NR 05:44 Clinical Research and Safety Profiles 07:13 Complexities in Boosting NAD+ Levels 09:04 Multi-Targeted Strategies for NAD+ Restoration 13:25 Conclusion: Embracing Complexity in Aging https://www.instagram.com/dr.williamwallace/ https://www.facebook.com/williamwallacePhD https://twitter.com/williamwallace https://www.linkedin.com/in/drwilliamwallace/ https://www.youtube-nocookie.com/embed/YxdJyvkat3w 829 2025-05-23T11:02:42.000Z 2026-10-22T20:11:48.359Z https://longevityharbor.com/en/watch/Yz0W-P0UaKE 307 ‒ Exercise for aging people: where to begin, and how to minimize risk while maximizing potential https://i.ytimg.com/vi/Yz0W-P0UaKE/hqdefault.jpg View show notes here: https://bit.ly/3RCspNr Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ In this special episode, Peter addresses the common questions about starting or returning to an exercise routine over the age of 50. Individuals in this age group have frequently reached out with questions about whether it's too late to start exercising and often express concern over a lack of prior training, a fear of injury, or uncertainty about where to begin. Peter delves into the importance of fitness for older adults, examining all four pillars of exercise, and provides practical advice on how to start exercising safely, minimize injury risk, and maximize potential benefits. Although this conversation focuses on people in the “older” age category, it also applies to anyone of any age who is deconditioned and looking to ease into regular exercise. We discuss: 0:00:00 - Intro 0:00:39 - Key points about starting exercise as an older adult 0:04:02 - Why it’s never too late to begin exercising and incorporating the four pillars of exercise 0:08:59 - The gradual, then sharp, decline in muscle mass and activity level that occur with age 0:14:44 - The decline of VO2 max that occurs with age 0:17:43 - Starting a training program: exercise variability, movement quality, realistic goals, and more 0:25:16 - Improving aerobic capacity: the malleability of the system, the importance of consistency, and setting long-term fitness goals 0:31:33 - Starting cardio training: base building, starting with low volume, and zone 2 training 0:38:17 - The critical role of VO2 max in longevity 0:48:04 - How to introduce VO2 max training to older or deconditioned individuals 0:57:02 - Options for performing zone 2 and VO2 max training 1:00:49 - The ability to make gains in strength and muscle mass as we age 1:05:21 - How to implement strength training for older individuals 1:12:40 - Advice for avoiding injury when strength train https://www.youtube-nocookie.com/embed/Yz0W-P0UaKE 6326 2024-06-24T07:30:08.000Z 2026-10-22T17:43:36.929Z https://longevityharbor.com/de/watch/Yz0W-P0UaKE 307 ‒ Exercise for aging people: where to begin, and how to minimize risk while maximizing potential https://i.ytimg.com/vi/Yz0W-P0UaKE/hqdefault.jpg View show notes here: https://bit.ly/3RCspNr Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ In this special episode, Peter addresses the common questions about starting or returning to an exercise routine over the age of 50. Individuals in this age group have frequently reached out with questions about whether it's too late to start exercising and often express concern over a lack of prior training, a fear of injury, or uncertainty about where to begin. Peter delves into the importance of fitness for older adults, examining all four pillars of exercise, and provides practical advice on how to start exercising safely, minimize injury risk, and maximize potential benefits. Although this conversation focuses on people in the “older” age category, it also applies to anyone of any age who is deconditioned and looking to ease into regular exercise. We discuss: 0:00:00 - Intro 0:00:39 - Key points about starting exercise as an older adult 0:04:02 - Why it’s never too late to begin exercising and incorporating the four pillars of exercise 0:08:59 - The gradual, then sharp, decline in muscle mass and activity level that occur with age 0:14:44 - The decline of VO2 max that occurs with age 0:17:43 - Starting a training program: exercise variability, movement quality, realistic goals, and more 0:25:16 - Improving aerobic capacity: the malleability of the system, the importance of consistency, and setting long-term fitness goals 0:31:33 - Starting cardio training: base building, starting with low volume, and zone 2 training 0:38:17 - The critical role of VO2 max in longevity 0:48:04 - How to introduce VO2 max training to older or deconditioned individuals 0:57:02 - Options for performing zone 2 and VO2 max training 1:00:49 - The ability to make gains in strength and muscle mass as we age 1:05:21 - How to implement strength training for older individuals 1:12:40 - Advice for avoiding injury when strength train https://www.youtube-nocookie.com/embed/Yz0W-P0UaKE 6326 2024-06-24T07:30:08.000Z 2026-10-22T17:43:36.929Z https://longevityharbor.com/en/watch/Z6AC22tV2p4 NAD+ NMN NaturalGenetic, pentru longevitate si regenerare celulara https://i.ytimg.com/vi/Z6AC22tV2p4/hqdefault.jpg Natural Genetic este un supliment destinat susținerii energiei celulare, metabolismului și proceselor biologice care încetinesc odată cu vârsta. #naturalgenetic #NMN #doctorcip #longevitate #antiaging Afla mai multe pe site-ul https://www.naturalgenetic.ro https://www.youtube-nocookie.com/embed/Z6AC22tV2p4 128 2025-09-27T17:19:03.000Z 2026-10-22T20:11:46.915Z https://longevityharbor.com/de/watch/Z6AC22tV2p4 NAD+ NMN NaturalGenetic, pentru longevitate si regenerare celulara https://i.ytimg.com/vi/Z6AC22tV2p4/hqdefault.jpg Natural Genetic este un supliment destinat susținerii energiei celulare, metabolismului și proceselor biologice care încetinesc odată cu vârsta. #naturalgenetic #NMN #doctorcip #longevitate #antiaging Afla mai multe pe site-ul https://www.naturalgenetic.ro https://www.youtube-nocookie.com/embed/Z6AC22tV2p4 128 2025-09-27T17:19:03.000Z 2026-10-22T20:11:46.915Z https://longevityharbor.com/en/watch/Z8wym1NNqy0 Warum deine Muskeln besonders im Alter so wichtig sind https://i.ytimg.com/vi/Z8wym1NNqy0/hqdefault.jpg 💪 Muskeln und gesundes Altern: Stärke für deine Lebensqualität Vom Sessel aufstehen, Einkäufe tragen, Treppen steigen und mit den Enkelkindern spielen: Wie wichtig unsere Muskelkraft ist, zeigt sich mitten im Alltag. In diesem Video spricht David darüber, welche Rolle Bewegung und Muskeltraining für Gesundheit und Selbstständigkeit spielen – und warum es sich auch im höheren Alter lohnt, die eigenen Möglichkeiten zu nutzen. Das erwartet dich: ✅ Muskeln als aktiver Teil unseres Stoffwechsels ✅ Muskelkraft und Selbstständigkeit im Alter ✅ Das Zusammenspiel von Kraft, Ausdauer und Gleichgewicht ✅ Bewegung als begleitender Bestandteil medizinischer Behandlung ✅ Spannende Forschungsergebnisse – und ihre Grenzen ✅ Kleine, realistische Schritte für einen aktiveren Alltag Es geht um Fortschritte, die für dein Leben zählen: sicherer unterwegs sein, vertraute Aufgaben leichter bewältigen und mehr Vertrauen in den eigenen Körper gewinnen. 💬 Welche Fähigkeit möchtest du dir bis ins hohe Alter erhalten? Schreib es in die Kommentare und abonniere den Kanal für weitere Impulse. Gesundheit und finanzielle Selbstbestimmung gehören für viele zu einer bewusst gestalteten Zukunft. Deshalb stellen wir zum Abschluss auch Polar Tensor vor, eine Plattform für vollautomatisiertes, KI-gestütztes Trading. Wenn du diesen Ansatz kennenlernen möchtest, findest du hier weitere Informationen. 🔗 Mehr Informationen zu Polar Tensor: https://polar-tensor-einblicke.chummy-olive-2578.chatgpt.site/ 👉 Registrierung über meinen Empfehlungslink: https://polar-tensor.com/sign/up/amadeus 🌐 Website: https://polar-tensor.com/ 🎬 Weitere Videos: https://www.youtube.com/playlist?list=PLUEEqvH6aO_8Q7e3X9ImqDisVARFRDAp7 📺 YouTube: https://youtube.com/@PolarTensor 📲 Telegram: https://t.me/polartensor 👥 Facebook: https://facebook.com/polartensor #Muskelkraft #GesundAltern #Krafttraining #Bewegung #Gesundheit #Selbstständigkeit #Lebensqualität #AktivImAlter #PolarTensor #KITrading #AutomatisiertesTrading https://www.youtube-nocookie.com/embed/Z8wym1NNqy0 964 2026-10-08T12:00:38.000Z 2026-10-22T18:54:05.100Z https://longevityharbor.com/de/watch/Z8wym1NNqy0 Warum deine Muskeln besonders im Alter so wichtig sind https://i.ytimg.com/vi/Z8wym1NNqy0/hqdefault.jpg 💪 Muskeln und gesundes Altern: Stärke für deine Lebensqualität Vom Sessel aufstehen, Einkäufe tragen, Treppen steigen und mit den Enkelkindern spielen: Wie wichtig unsere Muskelkraft ist, zeigt sich mitten im Alltag. In diesem Video spricht David darüber, welche Rolle Bewegung und Muskeltraining für Gesundheit und Selbstständigkeit spielen – und warum es sich auch im höheren Alter lohnt, die eigenen Möglichkeiten zu nutzen. Das erwartet dich: ✅ Muskeln als aktiver Teil unseres Stoffwechsels ✅ Muskelkraft und Selbstständigkeit im Alter ✅ Das Zusammenspiel von Kraft, Ausdauer und Gleichgewicht ✅ Bewegung als begleitender Bestandteil medizinischer Behandlung ✅ Spannende Forschungsergebnisse – und ihre Grenzen ✅ Kleine, realistische Schritte für einen aktiveren Alltag Es geht um Fortschritte, die für dein Leben zählen: sicherer unterwegs sein, vertraute Aufgaben leichter bewältigen und mehr Vertrauen in den eigenen Körper gewinnen. 💬 Welche Fähigkeit möchtest du dir bis ins hohe Alter erhalten? Schreib es in die Kommentare und abonniere den Kanal für weitere Impulse. Gesundheit und finanzielle Selbstbestimmung gehören für viele zu einer bewusst gestalteten Zukunft. Deshalb stellen wir zum Abschluss auch Polar Tensor vor, eine Plattform für vollautomatisiertes, KI-gestütztes Trading. Wenn du diesen Ansatz kennenlernen möchtest, findest du hier weitere Informationen. 🔗 Mehr Informationen zu Polar Tensor: https://polar-tensor-einblicke.chummy-olive-2578.chatgpt.site/ 👉 Registrierung über meinen Empfehlungslink: https://polar-tensor.com/sign/up/amadeus 🌐 Website: https://polar-tensor.com/ 🎬 Weitere Videos: https://www.youtube.com/playlist?list=PLUEEqvH6aO_8Q7e3X9ImqDisVARFRDAp7 📺 YouTube: https://youtube.com/@PolarTensor 📲 Telegram: https://t.me/polartensor 👥 Facebook: https://facebook.com/polartensor #Muskelkraft #GesundAltern #Krafttraining #Bewegung #Gesundheit #Selbstständigkeit #Lebensqualität #AktivImAlter #PolarTensor #KITrading #AutomatisiertesTrading https://www.youtube-nocookie.com/embed/Z8wym1NNqy0 964 2026-10-08T12:00:38.000Z 2026-10-22T18:54:05.100Z https://longevityharbor.com/en/watch/Z9J2AYq76Qs Video description: epigenetic clocks and lifestyle claims about biological age https://i.ytimg.com/vi/Z9J2AYq76Qs/hqdefault.jpg The description says epigenetic clocks estimate biological age from DNA methylation in a blood sample and that regular exercise, 7–9 hours of sleep, stress management and whole foods are linked to biological ages 5–10 years younger. These are creator claims; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/Z9J2AYq76Qs 101 2026-07-24T13:00:29.000Z 2026-10-22T23:23:04.947Z https://longevityharbor.com/de/watch/Z9J2AYq76Qs Videobeschreibung: epigenetische Uhren und Lebensstil-Aussagen zum biologischen Alter https://i.ytimg.com/vi/Z9J2AYq76Qs/hqdefault.jpg Die Beschreibung sagt, epigenetische Uhren schätzten das biologische Alter anhand von DNA-Methylierung aus einer Blutprobe, und regelmäßige Bewegung, 7–9 Stunden Schlaf, Stressmanagement und Vollwertkost würden mit einem biologischen Alter von 5–10 Jahren unter dem chronologischen in Verbindung gebracht. Das sind Aussagen des Erstellers; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/Z9J2AYq76Qs 101 2026-07-24T13:00:29.000Z 2026-10-22T23:23:04.947Z https://longevityharbor.com/en/watch/Z9rPPOedx_A What Time Should The Elderly Go to Bed After 70 For Better Health — Here's What Doctors Explain! https://i.ytimg.com/vi/Z9rPPOedx_A/hqdefault.jpg What Time Should The Elderly Go to Bed After 70 For Better Health — Here's What Doctors Explain: Are you struggling with sleep tips for seniors? Discover why hitting the right bedtime is more important than tracking your total sleep duration. For adults over 70, the timing of your rest is critical. Research shows that going to bed between 9:00 and 10:00 PM is essential for physical recovery. Missing this window can lead to increased fatigue and discomfort, regardless of how many hours you spend in bed. This guide explains why establishing the best bedtime for over 70 is the most effective way to improve your nightly rest. Beyond timing, your surroundings play a major role in how well you recover. We cover practical adjustments to create a cool, dark, and quiet bedroom environment that promotes consistent rest. Adopting these better sleep habits helps you align your body clock with natural repair cycles, making it easier to wake up feeling refreshed. If you want to build a more sustainable sleep environment, subscribe for weekly healthy sleep routine breakdowns. What is your biggest challenge when trying to fall asleep at night? Let us know in the comments. Timestamps: Research References: Suprachiasmatic nucleus aging: Farajnia, S. et al. (2012). Neuroscience & Biobehavioral Reviews. — circadian clock deterioration in aging. Melatonin phase advance in elderly: Duffy, J.F. et al. (2002). Journal of Sleep Research. Brigham and Women's Hospital / Harvard. Glymphatic system & amyloid clearance during sleep: Nedergaard, M. et al. (2013). Science. University of Rochester. Sleep timing & cardiovascular nocturnal dipping: Hermida, R.C. et al. (2010). Journal of the American College of Cardiology. Sleep misalignment & glucose regulation: Leproult, R. et al. (2014). Diabetes Care. — circadian disruption and insulin sensitivity. Blue light & melatonin suppression: Gooley, J.J. et al. (2011). Journal of Clinical Endocrinology & Metabolism. Harvard. Pre-sleep emotional arousal & slow-wave sleep in older adults: (2021) https://www.youtube-nocookie.com/embed/Z9rPPOedx_A 1153 2026-10-10T03:55:41.000Z 2026-10-22T19:43:49.652Z https://longevityharbor.com/de/watch/Z9rPPOedx_A What Time Should The Elderly Go to Bed After 70 For Better Health — Here's What Doctors Explain! https://i.ytimg.com/vi/Z9rPPOedx_A/hqdefault.jpg What Time Should The Elderly Go to Bed After 70 For Better Health — Here's What Doctors Explain: Are you struggling with sleep tips for seniors? Discover why hitting the right bedtime is more important than tracking your total sleep duration. For adults over 70, the timing of your rest is critical. Research shows that going to bed between 9:00 and 10:00 PM is essential for physical recovery. Missing this window can lead to increased fatigue and discomfort, regardless of how many hours you spend in bed. This guide explains why establishing the best bedtime for over 70 is the most effective way to improve your nightly rest. Beyond timing, your surroundings play a major role in how well you recover. We cover practical adjustments to create a cool, dark, and quiet bedroom environment that promotes consistent rest. Adopting these better sleep habits helps you align your body clock with natural repair cycles, making it easier to wake up feeling refreshed. If you want to build a more sustainable sleep environment, subscribe for weekly healthy sleep routine breakdowns. What is your biggest challenge when trying to fall asleep at night? Let us know in the comments. Timestamps: Research References: Suprachiasmatic nucleus aging: Farajnia, S. et al. (2012). Neuroscience & Biobehavioral Reviews. — circadian clock deterioration in aging. Melatonin phase advance in elderly: Duffy, J.F. et al. (2002). Journal of Sleep Research. Brigham and Women's Hospital / Harvard. Glymphatic system & amyloid clearance during sleep: Nedergaard, M. et al. (2013). Science. University of Rochester. Sleep timing & cardiovascular nocturnal dipping: Hermida, R.C. et al. (2010). Journal of the American College of Cardiology. Sleep misalignment & glucose regulation: Leproult, R. et al. (2014). Diabetes Care. — circadian disruption and insulin sensitivity. Blue light & melatonin suppression: Gooley, J.J. et al. (2011). Journal of Clinical Endocrinology & Metabolism. Harvard. Pre-sleep emotional arousal & slow-wave sleep in older adults: (2021) https://www.youtube-nocookie.com/embed/Z9rPPOedx_A 1153 2026-10-10T03:55:41.000Z 2026-10-22T19:43:49.652Z https://longevityharbor.com/en/watch/ZAA2C_T1Kss Video description ranks anti-ageing papers from 1996 to 2025 https://i.ytimg.com/vi/ZAA2C_T1Kss/hqdefault.jpg The description presents a bibliometric ranking of anti-ageing and geroscience publications from 1996 to the end of 2025, scored by citations, field-weighted citation impact, alignment with the Hallmarks of Aging and progression into Phase II/III human longevity trials. https://www.youtube-nocookie.com/embed/ZAA2C_T1Kss 263 2026-06-01T23:00:06.000Z 2026-10-23T00:07:41.259Z https://longevityharbor.com/de/watch/ZAA2C_T1Kss Videobeschreibung ordnet Anti-Aging-Arbeiten von 1996 bis 2025 ein https://i.ytimg.com/vi/ZAA2C_T1Kss/hqdefault.jpg Die Beschreibung stellt ein bibliometrisches Ranking von Anti-Aging- und Geroscience-Publikationen von 1996 bis Ende 2025 vor, bewertet nach Zitationen, feldgewichtetem Zitationsimpact, Übereinstimmung mit den Hallmarks of Aging und Fortschritt in Phase-II/III-Studien am Menschen. https://www.youtube-nocookie.com/embed/ZAA2C_T1Kss 263 2026-06-01T23:00:06.000Z 2026-10-23T00:07:41.259Z https://longevityharbor.com/en/watch/ZBYMDFPGm1k Rapamycin Longevity Lab is certified Vitalist Organization https://i.ytimg.com/vi/ZBYMDFPGm1k/hqdefault.jpg Rapamycin Longevity Lab is proud to announce we are joining the Vitalism Foundation as a Certified Vitalist Organization. https://www.vitalism.io Connect with Krister on: LinkedIn: https://www.linkedin.com/in/krister-kauppi X: https://x.com/KristerKauppi https://www.youtube-nocookie.com/embed/ZBYMDFPGm1k 438 2025-01-14T11:05:45.000Z 2026-10-22T19:32:35.480Z https://longevityharbor.com/de/watch/ZBYMDFPGm1k Rapamycin Longevity Lab is certified Vitalist Organization https://i.ytimg.com/vi/ZBYMDFPGm1k/hqdefault.jpg Rapamycin Longevity Lab is proud to announce we are joining the Vitalism Foundation as a Certified Vitalist Organization. https://www.vitalism.io Connect with Krister on: LinkedIn: https://www.linkedin.com/in/krister-kauppi X: https://x.com/KristerKauppi https://www.youtube-nocookie.com/embed/ZBYMDFPGm1k 438 2025-01-14T11:05:45.000Z 2026-10-22T19:32:35.480Z https://longevityharbor.com/en/watch/ZDP_qHwJwPY Video description: Stanford talk on optimizing exercise for health and longevity https://i.ytimg.com/vi/ZDP_qHwJwPY/hqdefault.jpg The description says Michael Fredericson, MD, presents research on the science and practice of fitness for longevity, health and performance; the video itself was not reviewed. https://www.youtube-nocookie.com/embed/ZDP_qHwJwPY 3511 2026-06-22T18:20:24.000Z 2026-10-22T23:50:52.360Z https://longevityharbor.com/de/watch/ZDP_qHwJwPY Videobeschreibung: Stanford-Vortrag zur Optimierung von Bewegung für Gesundheit und Langlebigkeit https://i.ytimg.com/vi/ZDP_qHwJwPY/hqdefault.jpg Laut Beschreibung stellt Michael Fredericson, MD, Forschung zur Wissenschaft und Praxis von Fitness für Langlebigkeit, Gesundheit und Leistung vor; das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/ZDP_qHwJwPY 3511 2026-06-22T18:20:24.000Z 2026-10-22T23:50:52.360Z https://longevityharbor.com/en/watch/ZG4sL62-TzI How Intermittent Fasting & CR Slow Down Aging https://i.ytimg.com/vi/ZG4sL62-TzI/hqdefault.jpg Two diets called caloric restriction and intermittent fasting claim that they can slow down aging. Both intermittent fasting and caloric restriction have become increasingly popular in the last years but can they really help us to live longer? Let's find out! 0:00 Introduction 1:29 What is Aging? 3:20 Caloric Restriction & Aging 7:09 Intermittent Fasting Slows Down Aging 🔬 Subscribe for more awesome biomedical research: https://bit.ly/2SRMqhC 🔬 Ready for awesome scientific discussion?! Join us on Discord: https://discord.gg/9VKnTSF Cells become older in various ways. Cells accumulate mutations over time which might lead to cancer. Stem cells which renew different parts of our body also become less efficient and mitochondria become less functional. In order to slow down aging we need to prove that A) we live longer and B) cells age slower. Let’s first talk about caloric restriction. We define caloric restriction as an overall 20-40% reduction of caloric intake. Studies have documented that caloric restriction increases the lifespan of various animals. Mice which have been maintained through their lives lived between 35-65% longer than control mice. In humans, caloric restriction helps to reduce weight, improve insulin-sensitivity and reduce the occurrence of cardiac risk factors. Cells also show less oxidative damage in their DNA and we find higher levels of proteins which are found in "young cells" (including AMPK and sirtuins, which are very famous proteins if we talk about aging). The activity of mitochondria is also increased if we undergo caloric restriction. Concerning intermittent fasting, it was noted that rats which were maintained on alternate day fasting throughout their lives lived nearly twice as long as control mice. In another study, it was found that older rats lived 30-40% longer if they start with the same diet. In humans, there are also different benefits from intermittent fasting such as weight loss, increased insulin sensitivity, decreased blood pressure and so on. Similar to caloric res https://www.youtube-nocookie.com/embed/ZG4sL62-TzI 615 2020-07-31T18:09:06.000Z 2026-10-22T17:43:38.433Z https://longevityharbor.com/de/watch/ZG4sL62-TzI How Intermittent Fasting & CR Slow Down Aging https://i.ytimg.com/vi/ZG4sL62-TzI/hqdefault.jpg Two diets called caloric restriction and intermittent fasting claim that they can slow down aging. Both intermittent fasting and caloric restriction have become increasingly popular in the last years but can they really help us to live longer? Let's find out! 0:00 Introduction 1:29 What is Aging? 3:20 Caloric Restriction & Aging 7:09 Intermittent Fasting Slows Down Aging 🔬 Subscribe for more awesome biomedical research: https://bit.ly/2SRMqhC 🔬 Ready for awesome scientific discussion?! Join us on Discord: https://discord.gg/9VKnTSF Cells become older in various ways. Cells accumulate mutations over time which might lead to cancer. Stem cells which renew different parts of our body also become less efficient and mitochondria become less functional. In order to slow down aging we need to prove that A) we live longer and B) cells age slower. Let’s first talk about caloric restriction. We define caloric restriction as an overall 20-40% reduction of caloric intake. Studies have documented that caloric restriction increases the lifespan of various animals. Mice which have been maintained through their lives lived between 35-65% longer than control mice. In humans, caloric restriction helps to reduce weight, improve insulin-sensitivity and reduce the occurrence of cardiac risk factors. Cells also show less oxidative damage in their DNA and we find higher levels of proteins which are found in "young cells" (including AMPK and sirtuins, which are very famous proteins if we talk about aging). The activity of mitochondria is also increased if we undergo caloric restriction. Concerning intermittent fasting, it was noted that rats which were maintained on alternate day fasting throughout their lives lived nearly twice as long as control mice. In another study, it was found that older rats lived 30-40% longer if they start with the same diet. In humans, there are also different benefits from intermittent fasting such as weight loss, increased insulin sensitivity, decreased blood pressure and so on. Similar to caloric res https://www.youtube-nocookie.com/embed/ZG4sL62-TzI 615 2020-07-31T18:09:06.000Z 2026-10-22T17:43:38.433Z https://longevityharbor.com/en/watch/ZIC24xi_DV8 Time’s arrow: Brief exposure to rapamycin has the same anti-ageing effects as lifelong treatment https://i.ytimg.com/vi/ZIC24xi_DV8/hqdefault.jpg Brief exposure with rapamycin has the same positive effects on lifespan and health in old age as a lifelong treatment, researchers from the Max Planck Institute for Biology of Aging show in fruit flies and mice. Rapamycin is currently the most promising anti-aging drug. To maximize the medicine's effectiveness, it is often administered for life. However, even at low doses used to prevent age-related decline, side effects can occur. Therefore, the shorter duration of treatment may make it more likely to be used in humans. --- Zeitfenster für Rapamycin: Kurze Einnahme hat gleiche Wirkung wie lebenslange Behandlung Eine kurze Behandlung mit Rapamycin hat die gleichen positiven Auswirkungen auf die Lebenszeit und die Gesundheit im Alter, wie eine lebenslange Behandlung, zeigen Forschende vom Max-Planck-Institut für Biologie des Alterns an Fruchtfliegen und Mäusen. Rapamycin ist das derzeit vielversprechendste Anti-Aging-Mittel. Allerdings wird es, um die maximale Wirksamkeit des Medikaments zu erzielen, oft lebenslang verabreicht. Doch selbst bei niedrigen Dosierungen, die zur Vorbeugung von altersbedingtem Verfall verwendet werden, können Nebenwirkungen auftreten. Daher könnte die kürzere Behandlungsdauer die Anwendung im Menschen wahrscheinlicher machen. Original Publication: Paula Juricic*, Yu-Xuan Lu*, Thomas Leech*, Lisa F. Drews, Jonathan Paulitz, Jiongming Lu, Tobias Nespital, Sina Azami, Jennifer C. Regan, Emilie Funk, Jenny Fröhlich, Sebastian Grönke, Linda Partridge Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy Nature Aging, 29 August 2022 https://www.nature.com/articles/s43587-022-00278-w *equal contribution https://www.youtube-nocookie.com/embed/ZIC24xi_DV8 139 2022-08-30T08:22:31.000Z 2026-10-22T17:43:41.755Z https://longevityharbor.com/de/watch/ZIC24xi_DV8 Time’s arrow: Brief exposure to rapamycin has the same anti-ageing effects as lifelong treatment https://i.ytimg.com/vi/ZIC24xi_DV8/hqdefault.jpg Brief exposure with rapamycin has the same positive effects on lifespan and health in old age as a lifelong treatment, researchers from the Max Planck Institute for Biology of Aging show in fruit flies and mice. Rapamycin is currently the most promising anti-aging drug. To maximize the medicine's effectiveness, it is often administered for life. However, even at low doses used to prevent age-related decline, side effects can occur. Therefore, the shorter duration of treatment may make it more likely to be used in humans. --- Zeitfenster für Rapamycin: Kurze Einnahme hat gleiche Wirkung wie lebenslange Behandlung Eine kurze Behandlung mit Rapamycin hat die gleichen positiven Auswirkungen auf die Lebenszeit und die Gesundheit im Alter, wie eine lebenslange Behandlung, zeigen Forschende vom Max-Planck-Institut für Biologie des Alterns an Fruchtfliegen und Mäusen. Rapamycin ist das derzeit vielversprechendste Anti-Aging-Mittel. Allerdings wird es, um die maximale Wirksamkeit des Medikaments zu erzielen, oft lebenslang verabreicht. Doch selbst bei niedrigen Dosierungen, die zur Vorbeugung von altersbedingtem Verfall verwendet werden, können Nebenwirkungen auftreten. Daher könnte die kürzere Behandlungsdauer die Anwendung im Menschen wahrscheinlicher machen. Original Publication: Paula Juricic*, Yu-Xuan Lu*, Thomas Leech*, Lisa F. Drews, Jonathan Paulitz, Jiongming Lu, Tobias Nespital, Sina Azami, Jennifer C. Regan, Emilie Funk, Jenny Fröhlich, Sebastian Grönke, Linda Partridge Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy Nature Aging, 29 August 2022 https://www.nature.com/articles/s43587-022-00278-w *equal contribution https://www.youtube-nocookie.com/embed/ZIC24xi_DV8 139 2022-08-30T08:22:31.000Z 2026-10-22T17:43:41.755Z https://longevityharbor.com/en/watch/ZK481WtfyL0 The Keys to Active Aging, from Longevity Expert & Orthopedic Surgeon Dr. Vonda Wright https://i.ytimg.com/vi/ZK481WtfyL0/hqdefault.jpg Dr. Vonda Wright is a world-renowned orthopedic surgeon and international authority on active aging and sports medicine. She has spent decades studying the science of healthy aging and active longevity. As part of Growing Bolder’s “Launchpad to What’s Next Live”, Dr. @vondawright shared her keys to active longevity – how we can all live longer, healthier and happier lives with simple lifestyle modifications like exercise, diet, and changing our attitude. #activeaging #aging #healthyaging #vondawright #growingbolder #longevity https://www.youtube-nocookie.com/embed/ZK481WtfyL0 1009 2023-07-28T14:28:31.000Z 2026-10-22T17:43:36.888Z https://longevityharbor.com/de/watch/ZK481WtfyL0 The Keys to Active Aging, from Longevity Expert & Orthopedic Surgeon Dr. Vonda Wright https://i.ytimg.com/vi/ZK481WtfyL0/hqdefault.jpg Dr. Vonda Wright is a world-renowned orthopedic surgeon and international authority on active aging and sports medicine. She has spent decades studying the science of healthy aging and active longevity. As part of Growing Bolder’s “Launchpad to What’s Next Live”, Dr. @vondawright shared her keys to active longevity – how we can all live longer, healthier and happier lives with simple lifestyle modifications like exercise, diet, and changing our attitude. #activeaging #aging #healthyaging #vondawright #growingbolder #longevity https://www.youtube-nocookie.com/embed/ZK481WtfyL0 1009 2023-07-28T14:28:31.000Z 2026-10-22T17:43:36.888Z https://longevityharbor.com/en/watch/ZLI1Zp4UiVw Kann man mit FISETIN und QUERCETIN wieder jünger werden? Seneszente Zellen entfernen mit Senolytika https://i.ytimg.com/vi/ZLI1Zp4UiVw/hqdefault.jpg Seneszente Zellen machen uns alt. Es sind Zellen, die das Ende ihrer Lebensspanne erreicht haben, aber nicht den Zelltod sterben wollen - stattdessen geistern sie durch unseren Körper und entzünden Zellen um sie herum - das macht uns alt. Man nennt sie auch Zombie-Zellen, weil sie "lebende tote" Zellen sind. Doch es gibt einen weg, sie aus dem Körper zu entfernen: Senolytika, wie Fisetin, Quercetin und Dasatinib. Studien an Menschen zeigen, dass wenn man Senolytika einnimmt, seneszente Zellen eliminiert werden - und der Körper so in eine jüngeren Zustand versetzt wird. Doch Achtung: Senolytika haben auch Nebenwirkungen. In diesem Video sprechen wir darüber, wie Zombie-Zellen entstehen, wie Senolytica arbeiten und sie aus dem Körper entfernen, und welche Nebenwirkungen unbedingt zu beachten sind. Viel Spaß beim Schauen! :) #Senolytika #Fisetin #Quercetin Werbung: Die nachfolgenden Produkt-Links sind Affiliate Links (*): Wenn du über diese Links etwas kaufst, erhalte ich eine kleine Vergütung, für dich entstehen dabei keinerlei Mehrkosten. Du kannst natürlich die Sachen auch woanders kaufen, ganz wie du magst. Danke, dass du meinen Kanal unterstützt. :) Disclaimer: Bitte sprecht unbedingt mit eurem Arzt, bevor ihr in Erwägung zieht, Supplements auszuprobieren - ich bin kein Arzt und gebe keine medizinischen Ratschläge. 💊Supplements, die ich nehme, um Altern aufzuhalten - auf alles 15% Rabatt mit dem Code "ANASTASIA":💊 * NMN: in EU hergestelltes Longevir NMN: https://avea-life.com/de/products/nmn?aff=ANASTASIARASTOR (1 Kapsel morgens mit Wasser) * Mein Longevity Bundle / alle Longevity-Wirkstoffe in einem Bundle: NMN, TMG, Trans-Resveratrol, Coenzym Q10, Pterostilben, Apigenin, Kollagen: https://avea-life.com/de/products/longevity-bundle?country=DE&utm_source=YOUTUBE&utm_medium=INFLUENCER&utm_campaign=YT-DACH-INFL-PURC-COLL-ANASTASIA-14462544&utm_term=BROD-YTD_-DACH-LONG-COLL&utm_content=COLL-VID-UGCC-HOME-BENE-D15X (jeden Morgen 1 Kapsel NMN, 1 Kapsel Booster, 1 Sachet Kollagenpulver in Wasser) * Ess https://www.youtube-nocookie.com/embed/ZLI1Zp4UiVw 956 2020-11-26T18:15:01.000Z 2026-10-23T02:24:27.185Z https://longevityharbor.com/de/watch/ZLI1Zp4UiVw Kann man mit FISETIN und QUERCETIN wieder jünger werden? Seneszente Zellen entfernen mit Senolytika https://i.ytimg.com/vi/ZLI1Zp4UiVw/hqdefault.jpg Seneszente Zellen machen uns alt. Es sind Zellen, die das Ende ihrer Lebensspanne erreicht haben, aber nicht den Zelltod sterben wollen - stattdessen geistern sie durch unseren Körper und entzünden Zellen um sie herum - das macht uns alt. Man nennt sie auch Zombie-Zellen, weil sie "lebende tote" Zellen sind. Doch es gibt einen weg, sie aus dem Körper zu entfernen: Senolytika, wie Fisetin, Quercetin und Dasatinib. Studien an Menschen zeigen, dass wenn man Senolytika einnimmt, seneszente Zellen eliminiert werden - und der Körper so in eine jüngeren Zustand versetzt wird. Doch Achtung: Senolytika haben auch Nebenwirkungen. In diesem Video sprechen wir darüber, wie Zombie-Zellen entstehen, wie Senolytica arbeiten und sie aus dem Körper entfernen, und welche Nebenwirkungen unbedingt zu beachten sind. Viel Spaß beim Schauen! :) #Senolytika #Fisetin #Quercetin Werbung: Die nachfolgenden Produkt-Links sind Affiliate Links (*): Wenn du über diese Links etwas kaufst, erhalte ich eine kleine Vergütung, für dich entstehen dabei keinerlei Mehrkosten. Du kannst natürlich die Sachen auch woanders kaufen, ganz wie du magst. Danke, dass du meinen Kanal unterstützt. :) Disclaimer: Bitte sprecht unbedingt mit eurem Arzt, bevor ihr in Erwägung zieht, Supplements auszuprobieren - ich bin kein Arzt und gebe keine medizinischen Ratschläge. 💊Supplements, die ich nehme, um Altern aufzuhalten - auf alles 15% Rabatt mit dem Code "ANASTASIA":💊 * NMN: in EU hergestelltes Longevir NMN: https://avea-life.com/de/products/nmn?aff=ANASTASIARASTOR (1 Kapsel morgens mit Wasser) * Mein Longevity Bundle / alle Longevity-Wirkstoffe in einem Bundle: NMN, TMG, Trans-Resveratrol, Coenzym Q10, Pterostilben, Apigenin, Kollagen: https://avea-life.com/de/products/longevity-bundle?country=DE&utm_source=YOUTUBE&utm_medium=INFLUENCER&utm_campaign=YT-DACH-INFL-PURC-COLL-ANASTASIA-14462544&utm_term=BROD-YTD_-DACH-LONG-COLL&utm_content=COLL-VID-UGCC-HOME-BENE-D15X (jeden Morgen 1 Kapsel NMN, 1 Kapsel Booster, 1 Sachet Kollagenpulver in Wasser) * Ess https://www.youtube-nocookie.com/embed/ZLI1Zp4UiVw 956 2020-11-26T18:15:01.000Z 2026-10-23T02:24:27.185Z https://longevityharbor.com/en/watch/ZMlYU61BOAo ARE "ZOMBIE CELLS" ACCELERATING YOUR AGING? https://i.ytimg.com/vi/ZMlYU61BOAo/hqdefault.jpg As we age, we accumulate senescent cells—cells that refuse to die and instead leak inflammatory "sludge" into our system. The solution? Senolytics. These aren't daily vitamins; they are a "clean-up crew" Here are the big three: Fisetin: The gold standard for clearing senescent immune cells. Landmark studies show it can significantly extend healthspan. Look for Liposomal versions for absorption. Quercetin: The "synergist." Most effective when used in the famous D+Q (Dasatinib + Quercetin) protocol to unmask and eliminate stubborn zombie cells. Look for Quercefit/Phytosome for 20x potency. PCC1 (Grape Seed Extract): The rising star. Research in Nature Metabolism showed it increased remaining lifespan in mice by over 60%. In clinical trials, these aren't taken daily. You only need to "mow the lawn" periodically. The standard research model is 2–3 days of dosing once a month. Stop just adding years to your life—start clearing the cellular clutter. https://www.youtube-nocookie.com/embed/ZMlYU61BOAo 94 2025-12-29T16:29:48.000Z 2026-10-22T20:11:51.358Z https://longevityharbor.com/de/watch/ZMlYU61BOAo ARE "ZOMBIE CELLS" ACCELERATING YOUR AGING? https://i.ytimg.com/vi/ZMlYU61BOAo/hqdefault.jpg As we age, we accumulate senescent cells—cells that refuse to die and instead leak inflammatory "sludge" into our system. The solution? Senolytics. These aren't daily vitamins; they are a "clean-up crew" Here are the big three: Fisetin: The gold standard for clearing senescent immune cells. Landmark studies show it can significantly extend healthspan. Look for Liposomal versions for absorption. Quercetin: The "synergist." Most effective when used in the famous D+Q (Dasatinib + Quercetin) protocol to unmask and eliminate stubborn zombie cells. Look for Quercefit/Phytosome for 20x potency. PCC1 (Grape Seed Extract): The rising star. Research in Nature Metabolism showed it increased remaining lifespan in mice by over 60%. In clinical trials, these aren't taken daily. You only need to "mow the lawn" periodically. The standard research model is 2–3 days of dosing once a month. Stop just adding years to your life—start clearing the cellular clutter. https://www.youtube-nocookie.com/embed/ZMlYU61BOAo 94 2025-12-29T16:29:48.000Z 2026-10-22T20:11:51.358Z https://longevityharbor.com/en/watch/ZNsq6RCxYWU 6 Golden Habits for Healthy Aging — Discover Them Now! https://i.ytimg.com/vi/ZNsq6RCxYWU/hqdefault.jpg What if healthy aging after 60 had less to do with expensive supplements and more to do with six simple habits you can build into your daily life? In this video, we break down 6 research-backed habits for healthier aging — from balance training and protein intake to deep sleep, social connection, daily walking, and progressive resistance training. You'll discover why balance exercises can help reduce fall risk, why older adults often need more protein to support muscle, how quality sleep supports brain health, why social connection matters for longevity, why 4,000–8,000 daily steps can be meaningful, and why properly supervised strength training can remain highly effective even into your 80s and beyond. Most importantly, this isn't about trying to look 30 again. It's about protecting strength, mobility, independence, brain health, and quality of life as you age. Watch until the end to discover the #1 habit that can help fight age-related muscle loss and preserve functional strength. 👍 If you found this helpful, like the video and subscribe to Aging Strong for more evidence-informed healthy-aging content. 💬 Question: Which of these six habits are you going to start this week? ⏱️ Timestamps 00:00 🔥 The 6 habits that can change how you age 01:18 🚶 The surprising walking statistic 02:32 ⚖️ #6 Balance & stability training 05:28 🥚 #5 Protein & anabolic resistance 08:55 😴 #4 Deep, uninterrupted sleep 12:15 🧠 How sleep supports brain cleanup 13:25 ❤️ #3 Social connection & longevity 16:18 🚶‍♂️ #2 Intentional walking & daily steps 19:20 💪 #1 Progressive resistance training 21:25 🏋️ Why strength training still works after 80 22:35 🌱 Building independence through daily habits 23:20 💬 Which habit will you start this week? healthy aging after 60, healthy aging habits, aging strong, senior health, healthy aging tips, longevity habits, habits for seniors, exercise after 60, strength training after 60, resistance training for seniors, walking for seniors, balance exercises for seniors, protein for older ad https://www.youtube-nocookie.com/embed/ZNsq6RCxYWU 1438 2026-09-02T20:06:23.000Z 2026-10-22T18:32:08.323Z https://longevityharbor.com/de/watch/ZNsq6RCxYWU 6 Golden Habits for Healthy Aging — Discover Them Now! https://i.ytimg.com/vi/ZNsq6RCxYWU/hqdefault.jpg What if healthy aging after 60 had less to do with expensive supplements and more to do with six simple habits you can build into your daily life? In this video, we break down 6 research-backed habits for healthier aging — from balance training and protein intake to deep sleep, social connection, daily walking, and progressive resistance training. You'll discover why balance exercises can help reduce fall risk, why older adults often need more protein to support muscle, how quality sleep supports brain health, why social connection matters for longevity, why 4,000–8,000 daily steps can be meaningful, and why properly supervised strength training can remain highly effective even into your 80s and beyond. Most importantly, this isn't about trying to look 30 again. It's about protecting strength, mobility, independence, brain health, and quality of life as you age. Watch until the end to discover the #1 habit that can help fight age-related muscle loss and preserve functional strength. 👍 If you found this helpful, like the video and subscribe to Aging Strong for more evidence-informed healthy-aging content. 💬 Question: Which of these six habits are you going to start this week? ⏱️ Timestamps 00:00 🔥 The 6 habits that can change how you age 01:18 🚶 The surprising walking statistic 02:32 ⚖️ #6 Balance & stability training 05:28 🥚 #5 Protein & anabolic resistance 08:55 😴 #4 Deep, uninterrupted sleep 12:15 🧠 How sleep supports brain cleanup 13:25 ❤️ #3 Social connection & longevity 16:18 🚶‍♂️ #2 Intentional walking & daily steps 19:20 💪 #1 Progressive resistance training 21:25 🏋️ Why strength training still works after 80 22:35 🌱 Building independence through daily habits 23:20 💬 Which habit will you start this week? healthy aging after 60, healthy aging habits, aging strong, senior health, healthy aging tips, longevity habits, habits for seniors, exercise after 60, strength training after 60, resistance training for seniors, walking for seniors, balance exercises for seniors, protein for older ad https://www.youtube-nocookie.com/embed/ZNsq6RCxYWU 1438 2026-09-02T20:06:23.000Z 2026-10-22T18:32:08.323Z https://longevityharbor.com/en/watch/ZORRqk9dPWc Do aging clocks work? A video description on biological age tests https://i.ytimg.com/vi/ZORRqk9dPWc/hqdefault.jpg The description says tests claim to measure biological age from blood or saliva, and asks what such a number measures, how good the clocks have become and whether it would change what happens to you. https://www.youtube-nocookie.com/embed/ZORRqk9dPWc 931 2026-07-14T10:00:29.000Z 2026-10-22T23:30:50.053Z https://longevityharbor.com/de/watch/ZORRqk9dPWc Funktionieren Altersuhren? Eine Videobeschreibung zu biologischen Alterstests https://i.ytimg.com/vi/ZORRqk9dPWc/hqdefault.jpg Laut Beschreibung behaupten Tests, das biologische Alter aus Blut oder Speichel zu messen; sie fragt, was diese Zahl misst, wie gut die Uhren wurden und ob sie ändern würde, was mit Ihnen geschieht. https://www.youtube-nocookie.com/embed/ZORRqk9dPWc 931 2026-07-14T10:00:29.000Z 2026-10-22T23:30:50.053Z https://longevityharbor.com/en/watch/ZS0_b2KWQos Implementing Horvath's Epigenetic Aging Clock From Scratch https://i.ytimg.com/vi/ZS0_b2KWQos/hqdefault.jpg Horvath's Epigenetic Aging Clock allows us to measure our biological age as opposed to our chronological age. But what does that actually mean? What exactly does Horvath's Clock measure? In this video, we’ll make sure we understand it correctly by implementing Horvath's Aging Clock from scratch using the same publicly available data as in the original paper. 📄 Horvath's original paper: https://genomebiology.biomedcentral.com/articles/10.1186/gb-2013-14-10-r115 💻 All code is available at: https://github.com/TKenneweg/HorvathsEpigeneticClock https://www.youtube-nocookie.com/embed/ZS0_b2KWQos 1613 2025-02-14T07:59:25.000Z 2026-10-22T18:54:04.145Z https://longevityharbor.com/de/watch/ZS0_b2KWQos Implementing Horvath's Epigenetic Aging Clock From Scratch https://i.ytimg.com/vi/ZS0_b2KWQos/hqdefault.jpg Horvath's Epigenetic Aging Clock allows us to measure our biological age as opposed to our chronological age. But what does that actually mean? What exactly does Horvath's Clock measure? In this video, we’ll make sure we understand it correctly by implementing Horvath's Aging Clock from scratch using the same publicly available data as in the original paper. 📄 Horvath's original paper: https://genomebiology.biomedcentral.com/articles/10.1186/gb-2013-14-10-r115 💻 All code is available at: https://github.com/TKenneweg/HorvathsEpigeneticClock https://www.youtube-nocookie.com/embed/ZS0_b2KWQos 1613 2025-02-14T07:59:25.000Z 2026-10-22T18:54:04.145Z https://longevityharbor.com/en/watch/ZbAgQz4dw4s Aging Speeds Up After 70 — 6 Science-Backed Ways to Age Better https://i.ytimg.com/vi/ZbAgQz4dw4s/hqdefault.jpg Does aging speed up after 70? Your body continues to respond to movement, nutrition, sleep, and other lifestyle habits throughout life. In this video, we explore what science says about healthy aging—and which habits may help support strength, energy, brain health, and independence as you grow older. 🧬 **WHAT YOU'LL LEARN** 💪 **Muscle & Protein:** How muscle supports strength, movement, and metabolic health as you age. 🧫 **Senescent Cells:** What researchers mean by “zombie cells” and why cellular senescence matters in aging research. 🔋 **Cellular Energy:** How mitochondria help power your cells and why regular physical activity matters. 🦠 **Gut Health:** How your gut microbiome is connected to health and aging. 😴 **Deep Sleep & Brain Health:** Why quality sleep is important for memory, recovery, and overall well-being. ❤️ **Longevity Research:** What research suggests about social connection, healthy habits, and living well for longer. 🚶 **PRACTICAL HABITS TO SUPPORT HEALTHY AGING** - Stay physically active at a level appropriate for your ability. - Include suitable strength-building exercise. - Eat a balanced diet with adequate protein. - Protect your sleep routine. - Support your gut health with a varied, fiber-rich diet. - Maintain meaningful social connections. The goal is not to promise that aging can be reversed completely. It is to understand how your body changes with age—and what evidence-informed habits may help you maintain strength, function, and independence. 💬 **QUESTION:** What matters most to you after 70: stronger muscles, better memory, more energy, or staying independent? 👍 Like this video if you found it helpful. 🔔 Subscribe to **Feynman Effect** for science-based explanations of aging, muscle, metabolism, mobility, and the human body. ⚠️ **MEDICAL DISCLAIMER** This video is for educational purposes only and is not medical advice. Research into aging and longevity is ongoing, and results from laboratory or early-stage studies do not necessarily translate into proven trea https://www.youtube-nocookie.com/embed/ZbAgQz4dw4s 1085 2026-10-12T15:00:14.000Z 2026-10-22T19:04:44.976Z https://longevityharbor.com/de/watch/ZbAgQz4dw4s Aging Speeds Up After 70 — 6 Science-Backed Ways to Age Better https://i.ytimg.com/vi/ZbAgQz4dw4s/hqdefault.jpg Does aging speed up after 70? Your body continues to respond to movement, nutrition, sleep, and other lifestyle habits throughout life. In this video, we explore what science says about healthy aging—and which habits may help support strength, energy, brain health, and independence as you grow older. 🧬 **WHAT YOU'LL LEARN** 💪 **Muscle & Protein:** How muscle supports strength, movement, and metabolic health as you age. 🧫 **Senescent Cells:** What researchers mean by “zombie cells” and why cellular senescence matters in aging research. 🔋 **Cellular Energy:** How mitochondria help power your cells and why regular physical activity matters. 🦠 **Gut Health:** How your gut microbiome is connected to health and aging. 😴 **Deep Sleep & Brain Health:** Why quality sleep is important for memory, recovery, and overall well-being. ❤️ **Longevity Research:** What research suggests about social connection, healthy habits, and living well for longer. 🚶 **PRACTICAL HABITS TO SUPPORT HEALTHY AGING** - Stay physically active at a level appropriate for your ability. - Include suitable strength-building exercise. - Eat a balanced diet with adequate protein. - Protect your sleep routine. - Support your gut health with a varied, fiber-rich diet. - Maintain meaningful social connections. The goal is not to promise that aging can be reversed completely. It is to understand how your body changes with age—and what evidence-informed habits may help you maintain strength, function, and independence. 💬 **QUESTION:** What matters most to you after 70: stronger muscles, better memory, more energy, or staying independent? 👍 Like this video if you found it helpful. 🔔 Subscribe to **Feynman Effect** for science-based explanations of aging, muscle, metabolism, mobility, and the human body. ⚠️ **MEDICAL DISCLAIMER** This video is for educational purposes only and is not medical advice. Research into aging and longevity is ongoing, and results from laboratory or early-stage studies do not necessarily translate into proven trea https://www.youtube-nocookie.com/embed/ZbAgQz4dw4s 1085 2026-10-12T15:00:14.000Z 2026-10-22T19:04:44.976Z https://longevityharbor.com/en/watch/ZffePuVjPBI NAD+ Explained: Energy, Aging, and What Actually Works https://i.ytimg.com/vi/ZffePuVjPBI/hqdefault.jpg Can NAD+ boosters give you more energy or help you live longer? This video explains what NAD+ actually does, how NMN and NR differ from NAD+ IVs, and what human studies show about endurance, brain fog, sleep, insulin sensitivity, and aging. We follow the biology from electron-carrying delivery trucks to cellular repair, then separate promising mechanisms from demonstrated benefits. What's covered: - NAD+, NADH, hydride transfer, mitochondria, and ATP - NMN and NR: the raw materials your body uses to make NAD+ - Why raising blood NAD+ is different from improving health - Fatigue versus endurance, and the amateur-runner trial - Brain fog, focus, sleep, and the circadian clock - Muscle insulin sensitivity and the prediabetic-women trial - Sirtuins, PARPs, CD38, cellular maintenance, and the longevity hypothesis - What the NAD+ IV pilot actually measured - Common supplement doses and why there is no established anti-aging dose 00:00 - More Energy and a Longer Life? The NAD+ Claims 03:11 - What NAD Actually Is 04:05 - Nicotinamide Adenine Dinucleotide, Explained 04:53 - NAD+, NADH, and the Delivery Truck Analogy 06:33 - NMN and NR: How We Raise NAD+ 08:19 - The Evidence Ladder 09:20 - Energy, Endurance, and the Bigger Battery Idea 11:19 - Feeling Less Tired vs. Performing Longer 12:55 - The Amateur-Runner Trial and Ventilatory Threshold 14:24 - Brain Fog, Focus, and Sleep 15:46 - Metabolism and Insulin Signaling 17:04 - The Prediabetic-Women Trial 18:30 - When NAD Might Be a Bottleneck 19:09 - Aging, Sirtuins, PARPs, and CD38 20:29 - Animal Results and the Human Lifespan Question 22:31 - NAD+ IVs: What the Blood-Level Study Shows 24:04 - Quick Recap 24:20 - Supplements, Common Doses, and the Takeaway NAD+ is one of dozens of therapies moving fast. Once a month I send the biggest news in peptides and emerging therapies, plus the best articles and threads I found. Sign up here (it's free): https://www.bioavailable.io/?utm_source=youtube&utm_medium=organic_video&utm_campaign=nad&utm_content=nad_description#newslette https://www.youtube-nocookie.com/embed/ZffePuVjPBI 1533 2026-10-10T14:00:32.000Z 2026-10-22T18:43:10.004Z https://longevityharbor.com/de/watch/ZffePuVjPBI NAD+ Explained: Energy, Aging, and What Actually Works https://i.ytimg.com/vi/ZffePuVjPBI/hqdefault.jpg Can NAD+ boosters give you more energy or help you live longer? This video explains what NAD+ actually does, how NMN and NR differ from NAD+ IVs, and what human studies show about endurance, brain fog, sleep, insulin sensitivity, and aging. We follow the biology from electron-carrying delivery trucks to cellular repair, then separate promising mechanisms from demonstrated benefits. What's covered: - NAD+, NADH, hydride transfer, mitochondria, and ATP - NMN and NR: the raw materials your body uses to make NAD+ - Why raising blood NAD+ is different from improving health - Fatigue versus endurance, and the amateur-runner trial - Brain fog, focus, sleep, and the circadian clock - Muscle insulin sensitivity and the prediabetic-women trial - Sirtuins, PARPs, CD38, cellular maintenance, and the longevity hypothesis - What the NAD+ IV pilot actually measured - Common supplement doses and why there is no established anti-aging dose 00:00 - More Energy and a Longer Life? The NAD+ Claims 03:11 - What NAD Actually Is 04:05 - Nicotinamide Adenine Dinucleotide, Explained 04:53 - NAD+, NADH, and the Delivery Truck Analogy 06:33 - NMN and NR: How We Raise NAD+ 08:19 - The Evidence Ladder 09:20 - Energy, Endurance, and the Bigger Battery Idea 11:19 - Feeling Less Tired vs. Performing Longer 12:55 - The Amateur-Runner Trial and Ventilatory Threshold 14:24 - Brain Fog, Focus, and Sleep 15:46 - Metabolism and Insulin Signaling 17:04 - The Prediabetic-Women Trial 18:30 - When NAD Might Be a Bottleneck 19:09 - Aging, Sirtuins, PARPs, and CD38 20:29 - Animal Results and the Human Lifespan Question 22:31 - NAD+ IVs: What the Blood-Level Study Shows 24:04 - Quick Recap 24:20 - Supplements, Common Doses, and the Takeaway NAD+ is one of dozens of therapies moving fast. Once a month I send the biggest news in peptides and emerging therapies, plus the best articles and threads I found. Sign up here (it's free): https://www.bioavailable.io/?utm_source=youtube&utm_medium=organic_video&utm_campaign=nad&utm_content=nad_description#newslette https://www.youtube-nocookie.com/embed/ZffePuVjPBI 1533 2026-10-10T14:00:32.000Z 2026-10-22T18:43:10.004Z https://longevityharbor.com/en/watch/Zg0coAzk5to Video description: protein needs, aging muscle and resistance exercise https://i.ytimg.com/vi/Zg0coAzk5to/hqdefault.jpg The description says the standard protein recommendation aims to prevent deficiency, not preserve muscle with age, and that aging muscle may need more protein per pound due to anabolic resistance. It also names resistance exercise as a critical part and advises people with kidney disease to consult a doctor. https://www.youtube-nocookie.com/embed/Zg0coAzk5to 543 2026-09-26T11:30:29.000Z 2026-10-22T21:48:38.232Z https://longevityharbor.com/de/watch/Zg0coAzk5to Videobeschreibung: Proteinbedarf, alternde Muskeln und Krafttraining https://i.ytimg.com/vi/Zg0coAzk5to/hqdefault.jpg Laut Beschreibung soll die Standard-Proteinempfehlung Mangel verhindern, nicht die Muskeln im Alter erhalten; alternde Muskeln brauchen möglicherweise wegen anabolischer Resistenz mehr Protein pro Pfund. Krafttraining nennt sie als wichtigen Teil, und Menschen mit Nierenerkrankung sollten ärztlichen Rat einholen. https://www.youtube-nocookie.com/embed/Zg0coAzk5to 543 2026-09-26T11:30:29.000Z 2026-10-22T21:48:38.232Z https://longevityharbor.com/en/watch/Zit6xHtudAg Are your cells secretly sabotaging your longevity? https://i.ytimg.com/vi/Zit6xHtudAg/hqdefault.jpg Are your cells secretly sabotaging your longevity? Why do we age? Why do we slow down, wrinkle, and eventually die? Science has broken it down into 12 hallmarks of aging, grouped into 3 key categories. Today we’re diving into the antagonistic hallmarks- the body’s damaging responses that speed up aging: • Cellular senescence: “Zombie cells” that linger and release toxic, inflammatory proteins. • Mitochondrial dysfunction: Energy factories of the cell losing power as NAD levels decline. • Deregulated nutrient sensing: Our modern diets overwhelm the body, causing excess damage. The good news? There are tools and strategies to fight back. From senolytic compounds like quercetin and fisetin, to NAD supplementation, to better nutrient balance- science is showing us ways to live longer, healthier, and better. 👉 Keep watching for more videos on how to live your best through the intersection of longevity medicine, biohacking, and living a fulfilled life. #AFulfilledLife #HallmarksofAging #TimCookMD #MarcKielburger #unlimitedlife ------------------------------------------------------------------------------------------------------ Marc Kielburger: Social Entrepreneur, Biohacking Advocate, and Legacy Architect Marc Kielburger is a husband, father, and internationally recognized social entrepreneur with over 30 years of experience empowering people and organizations to live with purpose. A passionate advocate for biohacking, longevity medicine, and human consciousness, Marc blends science and spirituality to help others achieve fulfilled, meaningful lives. https://www.youtube-nocookie.com/embed/Zit6xHtudAg 91 2025-09-03T15:58:29.000Z 2026-10-22T18:43:12.666Z https://longevityharbor.com/de/watch/Zit6xHtudAg Are your cells secretly sabotaging your longevity? https://i.ytimg.com/vi/Zit6xHtudAg/hqdefault.jpg Are your cells secretly sabotaging your longevity? Why do we age? Why do we slow down, wrinkle, and eventually die? Science has broken it down into 12 hallmarks of aging, grouped into 3 key categories. Today we’re diving into the antagonistic hallmarks- the body’s damaging responses that speed up aging: • Cellular senescence: “Zombie cells” that linger and release toxic, inflammatory proteins. • Mitochondrial dysfunction: Energy factories of the cell losing power as NAD levels decline. • Deregulated nutrient sensing: Our modern diets overwhelm the body, causing excess damage. The good news? There are tools and strategies to fight back. From senolytic compounds like quercetin and fisetin, to NAD supplementation, to better nutrient balance- science is showing us ways to live longer, healthier, and better. 👉 Keep watching for more videos on how to live your best through the intersection of longevity medicine, biohacking, and living a fulfilled life. #AFulfilledLife #HallmarksofAging #TimCookMD #MarcKielburger #unlimitedlife ------------------------------------------------------------------------------------------------------ Marc Kielburger: Social Entrepreneur, Biohacking Advocate, and Legacy Architect Marc Kielburger is a husband, father, and internationally recognized social entrepreneur with over 30 years of experience empowering people and organizations to live with purpose. A passionate advocate for biohacking, longevity medicine, and human consciousness, Marc blends science and spirituality to help others achieve fulfilled, meaningful lives. https://www.youtube-nocookie.com/embed/Zit6xHtudAg 91 2025-09-03T15:58:29.000Z 2026-10-22T18:43:12.666Z https://longevityharbor.com/en/watch/ZlQQk66UvXs NMN VS NAD from a cancer researcher https://i.ytimg.com/vi/ZlQQk66UvXs/hqdefault.jpg For a special discount use this link https://www.blackforestsupplements.com/EUGENIA22078 https://www.youtube-nocookie.com/embed/ZlQQk66UvXs 105 2026-02-18T11:21:26.000Z 2026-10-22T20:11:47.034Z https://longevityharbor.com/de/watch/ZlQQk66UvXs NMN VS NAD from a cancer researcher https://i.ytimg.com/vi/ZlQQk66UvXs/hqdefault.jpg For a special discount use this link https://www.blackforestsupplements.com/EUGENIA22078 https://www.youtube-nocookie.com/embed/ZlQQk66UvXs 105 2026-02-18T11:21:26.000Z 2026-10-22T20:11:47.034Z https://longevityharbor.com/en/watch/Znv-LQfHsww GeriEvidence Podcast Episode 2 https://i.ytimg.com/vi/Znv-LQfHsww/hqdefault.jpg Welcome to GeriEvidence: A High-Impact Research Podcast Episode 2: Geroscience - The New Frontier in Research and Clinical Care In this exciting episode, we are joined by Dr. Gustavo Duque, a leading expert in geroscience, to explore how this revolutionary field bridges aging biology with clinical practice. Discover the latest advancements and how geroscience is paving the way for healthier aging and innovative care solutions. This episode is proudly supported by the CIHR Institute of Aging and the Betty Havens Prize for Knowledge Mobilization in Aging, awarded to Dr. Alexandra Papaioannou. 💡 Dive into the cutting-edge of aging research and its transformative impact on clinical care! 👉 Don't forget to like, subscribe, and hit the notification bell to stay updated on our latest episodes! https://www.youtube-nocookie.com/embed/Znv-LQfHsww 605 2024-11-22T18:11:30.000Z 2026-10-22T19:04:38.604Z https://longevityharbor.com/de/watch/Znv-LQfHsww GeriEvidence Podcast Episode 2 https://i.ytimg.com/vi/Znv-LQfHsww/hqdefault.jpg Welcome to GeriEvidence: A High-Impact Research Podcast Episode 2: Geroscience - The New Frontier in Research and Clinical Care In this exciting episode, we are joined by Dr. Gustavo Duque, a leading expert in geroscience, to explore how this revolutionary field bridges aging biology with clinical practice. Discover the latest advancements and how geroscience is paving the way for healthier aging and innovative care solutions. This episode is proudly supported by the CIHR Institute of Aging and the Betty Havens Prize for Knowledge Mobilization in Aging, awarded to Dr. Alexandra Papaioannou. 💡 Dive into the cutting-edge of aging research and its transformative impact on clinical care! 👉 Don't forget to like, subscribe, and hit the notification bell to stay updated on our latest episodes! https://www.youtube-nocookie.com/embed/Znv-LQfHsww 605 2024-11-22T18:11:30.000Z 2026-10-22T19:04:38.604Z https://longevityharbor.com/en/watch/ZpJgtAsoDbs 2 excellent supplements for anti aging and longevity! #antiaging #over40 https://i.ytimg.com/vi/ZpJgtAsoDbs/hqdefault.jpg 2 excellent supplements for anti aging and longevity! #antiaging #over40 #microingredientsspotlightday #nmn #astaxanthin https://www.youtube-nocookie.com/embed/ZpJgtAsoDbs 104 2026-09-08T21:08:22.000Z 2026-10-22T20:11:46.803Z https://longevityharbor.com/de/watch/ZpJgtAsoDbs 2 excellent supplements for anti aging and longevity! #antiaging #over40 https://i.ytimg.com/vi/ZpJgtAsoDbs/hqdefault.jpg 2 excellent supplements for anti aging and longevity! #antiaging #over40 #microingredientsspotlightday #nmn #astaxanthin https://www.youtube-nocookie.com/embed/ZpJgtAsoDbs 104 2026-09-08T21:08:22.000Z 2026-10-22T20:11:46.803Z https://longevityharbor.com/en/watch/ZvZNMzlOIZ0 Hallmarks of Aging Ep.10 Autophagy https://i.ytimg.com/vi/ZvZNMzlOIZ0/hqdefault.jpg คำว่า autophagy ซึ่งหมายถึงกลไกการกินตัวเองของเซลล์ หรือ มาจากภาษากรีกที่แปลว่า "ตัวเอง" และ "กิน" กลไกนี้เป็นกระบวนการ ซึ่งเซลล์สลายตัวและเริ่มนำส่วนประกอบของเซลล์กลับมาใช้ใหม่ กลไกนี้ช่วยให้พลังงานและสร้างพื้นที่สำหรับใช้ในการฟื้นฟูเซลล์ขึ้นมาใหม่ หลังการติดเชื้อ กลไกการกินตัวเองของเซลล์สามารถทำลายแบคทีเรียและไวรัสต่าง ๆ ได้ เซลล์ใช้กลไกการกินตัวเองเพื่อกำจัดโปรตีนและออร์แกเนลล์ที่เสียหาย เพื่อลดผลกระทบด้านลบที่ทำให้เกิดการเสื่อมถอยของร่างกาย #hallmarksofaging #autophagy #longevity #สุขภาพดี #อายุยืน #THELONGEVIST https://www.youtube-nocookie.com/embed/ZvZNMzlOIZ0 1704 2023-10-31T15:01:15.000Z 2026-10-22T19:54:19.256Z https://longevityharbor.com/de/watch/ZvZNMzlOIZ0 Hallmarks of Aging Ep.10 Autophagy https://i.ytimg.com/vi/ZvZNMzlOIZ0/hqdefault.jpg คำว่า autophagy ซึ่งหมายถึงกลไกการกินตัวเองของเซลล์ หรือ มาจากภาษากรีกที่แปลว่า "ตัวเอง" และ "กิน" กลไกนี้เป็นกระบวนการ ซึ่งเซลล์สลายตัวและเริ่มนำส่วนประกอบของเซลล์กลับมาใช้ใหม่ กลไกนี้ช่วยให้พลังงานและสร้างพื้นที่สำหรับใช้ในการฟื้นฟูเซลล์ขึ้นมาใหม่ หลังการติดเชื้อ กลไกการกินตัวเองของเซลล์สามารถทำลายแบคทีเรียและไวรัสต่าง ๆ ได้ เซลล์ใช้กลไกการกินตัวเองเพื่อกำจัดโปรตีนและออร์แกเนลล์ที่เสียหาย เพื่อลดผลกระทบด้านลบที่ทำให้เกิดการเสื่อมถอยของร่างกาย #hallmarksofaging #autophagy #longevity #สุขภาพดี #อายุยืน #THELONGEVIST https://www.youtube-nocookie.com/embed/ZvZNMzlOIZ0 1704 2023-10-31T15:01:15.000Z 2026-10-22T19:54:19.256Z https://longevityharbor.com/en/watch/ZwdhdevxlRg #1 LONGEVITY SCIENTIST Reveals The Optimal Fasting Window For Longevity https://i.ytimg.com/vi/ZwdhdevxlRg/hqdefault.jpg Dr. Valter Longo, Director of USC's Longevity Institute and one of TIME's 50 most influential people in healthcare, reveals the mechanistic power of therapeutic fasting. We discuss his groundbreaking Fasting Mimicking Diet, its implications for cancer treatment, disease reversal, and extending human healthspan. READ MORE👉🏾 https://bit.ly/richroll889 ✌🏼🌱 - Rich This Episode Is Brought To You By… Seed: Use code RICHROLL25 to get 25% off your first month 👉https://bit.ly/seedxrrp2025 Squarespace: Use code RichRoll to save 10% off 👉https://bit.ly/squarespace2025 BetterHelp: Use the code RICHROLL to get 10% off your first month 👉BetterHelp.com/richroll On: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll Check out all of the amazing discounts from our Sponsors 👉🏾 https://bit.ly/rrpsponsors LISTEN / SUBSCRIBE TO THE PODCAST Apple Podcasts: http://bit.ly/rrpitunes Spotify: http://bit.ly/rrpspotify Google: http://bit.ly/rrpgooglepods Meal Planner: http://meals.richroll.com Voicing Change Book: http://richroll.com/vc Clips Channel: https://www.youtube.com/c/RichRollPodcastClips Newsletter: http://bit.ly/rollcallemail CHAPTERS 00:00:00 Intro 00:03:54 Funding for Research and Clinical Trials 00:05:29 Role of NIH in Research and Clinical Trials 00:06:45 Latest Findings on Fasting and Time-Restricted Eating 00:07:21 Efficacy of 12-Hour Fasting Window 00:10:31 Fasting-Mimicking Diet 00:11:54 Understanding Time-Restricted Eating 00:13:27 Impact of Eating Habits on Sleep 00:16:36 Exploration of Calorie Restriction and Fasting-Mimicking Diet 00:17:50 The Longevity Diet and Comparing Different Diets 00:18:29 Understanding the Impact of Individual Food Items 00:20:03 Role of Genetics in Diet and Aging 00:21:52 Potential of Fasting-Mimicking Diet in Disease Treatment 00:26:03 Understanding the Mechanisms of Fasting Diets 00:27:42 Metabolic Switches and Energy Modes 00:29:56 Challenges in Weight Loss and Energy Saving Mode 00:33:17 Ad Break 00:35:21 Role of Fasting-Mimicking Diet in Diseas https://www.youtube-nocookie.com/embed/ZwdhdevxlRg 7137 2025-02-10T11:00:47.000Z 2026-10-22T19:32:32.105Z https://longevityharbor.com/de/watch/ZwdhdevxlRg #1 LONGEVITY SCIENTIST Reveals The Optimal Fasting Window For Longevity https://i.ytimg.com/vi/ZwdhdevxlRg/hqdefault.jpg Dr. Valter Longo, Director of USC's Longevity Institute and one of TIME's 50 most influential people in healthcare, reveals the mechanistic power of therapeutic fasting. We discuss his groundbreaking Fasting Mimicking Diet, its implications for cancer treatment, disease reversal, and extending human healthspan. READ MORE👉🏾 https://bit.ly/richroll889 ✌🏼🌱 - Rich This Episode Is Brought To You By… Seed: Use code RICHROLL25 to get 25% off your first month 👉https://bit.ly/seedxrrp2025 Squarespace: Use code RichRoll to save 10% off 👉https://bit.ly/squarespace2025 BetterHelp: Use the code RICHROLL to get 10% off your first month 👉BetterHelp.com/richroll On: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll Check out all of the amazing discounts from our Sponsors 👉🏾 https://bit.ly/rrpsponsors LISTEN / SUBSCRIBE TO THE PODCAST Apple Podcasts: http://bit.ly/rrpitunes Spotify: http://bit.ly/rrpspotify Google: http://bit.ly/rrpgooglepods Meal Planner: http://meals.richroll.com Voicing Change Book: http://richroll.com/vc Clips Channel: https://www.youtube.com/c/RichRollPodcastClips Newsletter: http://bit.ly/rollcallemail CHAPTERS 00:00:00 Intro 00:03:54 Funding for Research and Clinical Trials 00:05:29 Role of NIH in Research and Clinical Trials 00:06:45 Latest Findings on Fasting and Time-Restricted Eating 00:07:21 Efficacy of 12-Hour Fasting Window 00:10:31 Fasting-Mimicking Diet 00:11:54 Understanding Time-Restricted Eating 00:13:27 Impact of Eating Habits on Sleep 00:16:36 Exploration of Calorie Restriction and Fasting-Mimicking Diet 00:17:50 The Longevity Diet and Comparing Different Diets 00:18:29 Understanding the Impact of Individual Food Items 00:20:03 Role of Genetics in Diet and Aging 00:21:52 Potential of Fasting-Mimicking Diet in Disease Treatment 00:26:03 Understanding the Mechanisms of Fasting Diets 00:27:42 Metabolic Switches and Energy Modes 00:29:56 Challenges in Weight Loss and Energy Saving Mode 00:33:17 Ad Break 00:35:21 Role of Fasting-Mimicking Diet in Diseas https://www.youtube-nocookie.com/embed/ZwdhdevxlRg 7137 2025-02-10T11:00:47.000Z 2026-10-22T19:32:32.105Z https://longevityharbor.com/en/watch/ZwpMXsFCrco Learning These Facts About NMN Changed How I Think About Aging—And It Could Change Your Life Too! https://i.ytimg.com/vi/ZwpMXsFCrco/hqdefault.jpg Discover how NMN (Nicotinamide Mononucleotide) is reshaping the science of aging in this concise, data-driven video! We dive into the latest clinical research revealing NMN's potential to boost NAD+ levels, enhance muscle strength, improve metabolism, and slow cellular aging. Learn about safe dosing strategies, affordability, and what makes a quality NMN supplement. Backed by recent studies, this video offers a clear, scientific perspective on whether NMN could be your next step toward healthier, energized aging. Perfect for health seekers eager to understand longevity supplements through evidence-based insights. Like and share this video to spread cutting-edge knowledge on anti-aging science! #NMN #Longevity #AntiAging #NAD+ #HealthSupplements #ScienceExplained #HealthyAging OUTLINE: 00:00:00 Introduction to NMN 00:00:27 What is NMN 00:00:51 The Science and Research 00:02:10 Cost and Value 00:02:39 Safety and Dosage Information 00:03:50 Conclusion and Call to Action https://www.youtube-nocookie.com/embed/ZwpMXsFCrco 271 2025-07-01T18:21:12.000Z 2026-10-22T20:11:48.231Z https://longevityharbor.com/de/watch/ZwpMXsFCrco Learning These Facts About NMN Changed How I Think About Aging—And It Could Change Your Life Too! https://i.ytimg.com/vi/ZwpMXsFCrco/hqdefault.jpg Discover how NMN (Nicotinamide Mononucleotide) is reshaping the science of aging in this concise, data-driven video! We dive into the latest clinical research revealing NMN's potential to boost NAD+ levels, enhance muscle strength, improve metabolism, and slow cellular aging. Learn about safe dosing strategies, affordability, and what makes a quality NMN supplement. Backed by recent studies, this video offers a clear, scientific perspective on whether NMN could be your next step toward healthier, energized aging. Perfect for health seekers eager to understand longevity supplements through evidence-based insights. Like and share this video to spread cutting-edge knowledge on anti-aging science! #NMN #Longevity #AntiAging #NAD+ #HealthSupplements #ScienceExplained #HealthyAging OUTLINE: 00:00:00 Introduction to NMN 00:00:27 What is NMN 00:00:51 The Science and Research 00:02:10 Cost and Value 00:02:39 Safety and Dosage Information 00:03:50 Conclusion and Call to Action https://www.youtube-nocookie.com/embed/ZwpMXsFCrco 271 2025-07-01T18:21:12.000Z 2026-10-22T20:11:48.231Z https://longevityharbor.com/en/watch/_24QkxhmLQ0 NMN oder NR wirkungsvoller für gesundes Altern? (Studien) https://i.ytimg.com/vi/_24QkxhmLQ0/hqdefault.jpg Wegen ihrer potenziellen Wirkung bekommen die Supplements NMN (Nicotinamid Mononukleotid) und NR (Nicotinamid-Ribosid) gerade immer mehr Aufmerksamkeit. Der bekannte Genetikforscher Prof. David Sinclair beispielsweise berichtet von den positiven Effekten als Nahrungsergänzung. Aber welches der beiden kann laut wissenschaftlichen Studien als Testsieger aus dem Rennen gehen? Findet es in diesem Video heraus! 💡Artikel zu Longevity Nahrungsergänzungsmittel & mehr: https://nuo.life/ Hinterlasst gerne einen Kommentar! Ich lese jeden einzelnen und versuche innerhalb von 24 Stunden zu antworten 💬 ► ⌚️ KAPITEL 00:00 Intro 00:10 NMN und NR als NAD-Booster 00:35 Studienlage 01:25 Bedenken bei der Sicherheit? 02:36 Welches Supplement wirkt besser? 03:39 Auswirkungen der Aufnahme 04:57 Fazit 📖 Quellenangaben: [1] Damgaard MV, Treebak JT. What is really known about the effects of nicotinamide riboside supplementation in humans. doi: 10.1126/sciadv.adi4862. [2] Song et al. The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update. doi: 10.1016/j.advnut.2023.08.008. [3] Igarashi et al. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men. doi: 10.1038/s41514-022-00084-z. [4] Martens et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. doi: 10.1038/s41467-018-03421-7. Weitere Quellen: • Yi et al. (2023) doi: 10.1007/s11357-022-00705-1 • Katayoshi et al. (2023) doi: 10.1038/s41598-023-29787-3 • Brakedal et al. (2022) doi: 10.1016/j.cmet.2022.02.001 • Elhassan et al. (2019) doi: 10.1016/j.cmet.2022.02.001 🟣 NAD-Booster: Was bringen sie? ➡️ https://youtu.be/f8LNYcymw3Q 🟣 Was NAD+ genau ist und was es so wichtig macht ➡️ https://youtu.be/6__IKZC9uns 🟣 NAD+-Level natürlich boosten: Top 3 Rezeptideen ➡️ https://youtu.be/kgYOPh86jWM 🟣 Wie mein Burnout mich zum Thema Longevity gebracht hat ➡️ ht https://www.youtube-nocookie.com/embed/_24QkxhmLQ0 346 2024-08-08T15:00:38.000Z 2026-10-22T17:43:42.517Z https://longevityharbor.com/de/watch/_24QkxhmLQ0 NMN oder NR wirkungsvoller für gesundes Altern? (Studien) https://i.ytimg.com/vi/_24QkxhmLQ0/hqdefault.jpg Wegen ihrer potenziellen Wirkung bekommen die Supplements NMN (Nicotinamid Mononukleotid) und NR (Nicotinamid-Ribosid) gerade immer mehr Aufmerksamkeit. Der bekannte Genetikforscher Prof. David Sinclair beispielsweise berichtet von den positiven Effekten als Nahrungsergänzung. Aber welches der beiden kann laut wissenschaftlichen Studien als Testsieger aus dem Rennen gehen? Findet es in diesem Video heraus! 💡Artikel zu Longevity Nahrungsergänzungsmittel & mehr: https://nuo.life/ Hinterlasst gerne einen Kommentar! Ich lese jeden einzelnen und versuche innerhalb von 24 Stunden zu antworten 💬 ► ⌚️ KAPITEL 00:00 Intro 00:10 NMN und NR als NAD-Booster 00:35 Studienlage 01:25 Bedenken bei der Sicherheit? 02:36 Welches Supplement wirkt besser? 03:39 Auswirkungen der Aufnahme 04:57 Fazit 📖 Quellenangaben: [1] Damgaard MV, Treebak JT. What is really known about the effects of nicotinamide riboside supplementation in humans. doi: 10.1126/sciadv.adi4862. [2] Song et al. The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update. doi: 10.1016/j.advnut.2023.08.008. [3] Igarashi et al. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men. doi: 10.1038/s41514-022-00084-z. [4] Martens et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. doi: 10.1038/s41467-018-03421-7. Weitere Quellen: • Yi et al. (2023) doi: 10.1007/s11357-022-00705-1 • Katayoshi et al. (2023) doi: 10.1038/s41598-023-29787-3 • Brakedal et al. (2022) doi: 10.1016/j.cmet.2022.02.001 • Elhassan et al. (2019) doi: 10.1016/j.cmet.2022.02.001 🟣 NAD-Booster: Was bringen sie? ➡️ https://youtu.be/f8LNYcymw3Q 🟣 Was NAD+ genau ist und was es so wichtig macht ➡️ https://youtu.be/6__IKZC9uns 🟣 NAD+-Level natürlich boosten: Top 3 Rezeptideen ➡️ https://youtu.be/kgYOPh86jWM 🟣 Wie mein Burnout mich zum Thema Longevity gebracht hat ➡️ ht https://www.youtube-nocookie.com/embed/_24QkxhmLQ0 346 2024-08-08T15:00:38.000Z 2026-10-22T17:43:42.517Z https://longevityharbor.com/en/watch/_3Rhi1Op6bQ Epigenetics Meets Geroscience: Unlocking New Frontiers - Michael Corley, PhD https://i.ytimg.com/vi/_3Rhi1Op6bQ/hqdefault.jpg - Presenter: Michael Corley, PhD | Weill Cornell Medicine, United States - Lecture: Epigenetics Meets Geroscience: Unlocking New Frontiers in HIV Research and Aging - Presented in Session 5: Geroscience/Frailty Meeting Name - 15th International Workshop on HIV & Aging - Subscribe to our newsletter: https://amededu.activehosted.com/f/13 - For more information, visit: https://academicmedicaleducation.com/ - Upcoming meetings: https://academicmedicaleducation.com/programs - See next year’s edition: https://academicmedicaleducation.com/meeting/16th-international-workshop-hiv-aging-2025 Meeting Description The integration of antiretroviral therapy (ART) into HIV care has dramatically extended the life expectancy of those living with HIV. This increased life expectancy is changing the demographics of the HIV epidemic. Currently, over half of individuals living with HIV are aged 50 or older. Recent estimates in Europe suggest that more than 70% of those with HIV will be over the age of 50 by 2030, accompanied by a greater burden of comorbidities and the associated treatments. In comparison to similar populations, persons with HIV, even when on effective ART, experience an excess of morbidity and mortality. Complications due to AIDS are rarely fatal for persons on ART. Instead, patients experience an early onset of aging complications, including neurocognitive decline, osteoporosis and fractures, impaired physical function, frailty, and falls. Improving the management of older adults with HIV will require a much deeper understanding of the interface between aging, HIV, associated comorbid conditions, and concurrent treatment. Additionally, research is needed to address the unique psychosocial challenges faced by this growing population. The elderly population living with HIV is particularly vulnerable to social stigma, which can lead to depression, psychological distress, compromised adherence to therapy, and overall poor treatment outcomes and quality of life. The International Workshop on Aging and HIV remains the https://www.youtube-nocookie.com/embed/_3Rhi1Op6bQ 1158 2024-11-13T14:00:53.000Z 2026-10-22T19:04:38.871Z https://longevityharbor.com/de/watch/_3Rhi1Op6bQ Epigenetics Meets Geroscience: Unlocking New Frontiers - Michael Corley, PhD https://i.ytimg.com/vi/_3Rhi1Op6bQ/hqdefault.jpg - Presenter: Michael Corley, PhD | Weill Cornell Medicine, United States - Lecture: Epigenetics Meets Geroscience: Unlocking New Frontiers in HIV Research and Aging - Presented in Session 5: Geroscience/Frailty Meeting Name - 15th International Workshop on HIV & Aging - Subscribe to our newsletter: https://amededu.activehosted.com/f/13 - For more information, visit: https://academicmedicaleducation.com/ - Upcoming meetings: https://academicmedicaleducation.com/programs - See next year’s edition: https://academicmedicaleducation.com/meeting/16th-international-workshop-hiv-aging-2025 Meeting Description The integration of antiretroviral therapy (ART) into HIV care has dramatically extended the life expectancy of those living with HIV. This increased life expectancy is changing the demographics of the HIV epidemic. Currently, over half of individuals living with HIV are aged 50 or older. Recent estimates in Europe suggest that more than 70% of those with HIV will be over the age of 50 by 2030, accompanied by a greater burden of comorbidities and the associated treatments. In comparison to similar populations, persons with HIV, even when on effective ART, experience an excess of morbidity and mortality. Complications due to AIDS are rarely fatal for persons on ART. Instead, patients experience an early onset of aging complications, including neurocognitive decline, osteoporosis and fractures, impaired physical function, frailty, and falls. Improving the management of older adults with HIV will require a much deeper understanding of the interface between aging, HIV, associated comorbid conditions, and concurrent treatment. Additionally, research is needed to address the unique psychosocial challenges faced by this growing population. The elderly population living with HIV is particularly vulnerable to social stigma, which can lead to depression, psychological distress, compromised adherence to therapy, and overall poor treatment outcomes and quality of life. The International Workshop on Aging and HIV remains the https://www.youtube-nocookie.com/embed/_3Rhi1Op6bQ 1158 2024-11-13T14:00:53.000Z 2026-10-22T19:04:38.871Z https://longevityharbor.com/en/watch/_50niHy8IK0 Video description: NMN as a control input for NAD⁺-dependent systems https://i.ytimg.com/vi/_50niHy8IK0/hqdefault.jpg The description says the video examines how NMN acts as a control input for NAD⁺-dependent systems, including sirtuins, PARPs, CD38, epigenetic stability, mitochondrial networks and circadian timing. It also lists transport, methylation costs, cancer considerations and timing or dosing as topics. https://www.youtube-nocookie.com/embed/_50niHy8IK0 398 2026-01-01T09:10:54.000Z 2026-10-23T03:02:35.799Z https://longevityharbor.com/de/watch/_50niHy8IK0 Videobeschreibung: NMN als Steuergröße für NAD⁺-abhängige Systeme https://i.ytimg.com/vi/_50niHy8IK0/hqdefault.jpg Laut Beschreibung untersucht das Video, wie NMN als Steuergröße für NAD⁺-abhängige Systeme wirkt, darunter Sirtuine, PARPs, CD38, epigenetische Stabilität, mitochondriale Netzwerke und circadiane Zeitgebung. Zudem nennt sie Transport, Methylierungskosten, Krebsaspekte sowie Zeitpunkt und Dosierung als Themen. https://www.youtube-nocookie.com/embed/_50niHy8IK0 398 2026-01-01T09:10:54.000Z 2026-10-23T03:02:35.799Z https://longevityharbor.com/en/watch/_73-t1_Z9_c Longevity, Metabolism & Mood: The Science of Circadian Health | ANEW Insight 113 https://i.ytimg.com/vi/_73-t1_Z9_c/hqdefault.jpg Your body runs on clocks you can’t see circadian rhythms that govern sleep, energy, metabolism, mood, and even longevity. In this episode of the ANEW Insight Podcast, Dr. Supatra Tovar sits down with a leading circadian science expert to reveal how timing your sleep, light exposure, and eating patterns can transform health in ways diet and exercise alone cannot. We explore why sleep is not passive rest but a nightly repair system that detoxifies the brain, resets hormones, and repairs tissues. You’ll learn how every organ—gut, skin, even hair—operates on its own internal schedule, and why ignoring these rhythms leads to fatigue, weight gain, mood imbalances, and chronic disease. This episode also unpacks the so-called “night owl” myth, showing how late-night habits are often driven by artificial light, stimulants, and lifestyle—not unchangeable genetics. With practical tools you can apply today, you’ll understand why consistent sleep, natural light exposure, and a defined eating window create a foundation for long-term vitality. ✨ Highlights from this episode include: 1. Why sleep is your body’s “operating theater” for repair and brain detox 2. The discovery of light-sensing proteins and their role in resetting the body clock 3. How circadian rhythms evolved for survival and still shape modern health 4. The truth about “night owls” and why most people are naturally aligned with morning light 5. Practical tips for sleep hygiene, light exposure, and daily rhythm alignment 6. A preview of Part Two: how eating within an 8–10 hour window can reset metabolism 🕒 Timestamps 00:00 – Welcome and introduction to circadian research 02:00 – How internal clocks influence health, weight, and aging 05:00 – From plants to humans: the biology of circadian rhythms 08:30 – Light-sensing proteins and the science of resetting sleep cycles 12:00 – Why circadian rhythms evolved as survival mechanisms 16:00 – Sleep as nightly repair: gut lining, skin, and brain detox 20:00 – The night owl myth explained through light and lifes https://www.youtube-nocookie.com/embed/_73-t1_Z9_c 742 2025-09-29T22:00:51.000Z 2026-10-22T18:54:02.090Z https://longevityharbor.com/de/watch/_73-t1_Z9_c Longevity, Metabolism & Mood: The Science of Circadian Health | ANEW Insight 113 https://i.ytimg.com/vi/_73-t1_Z9_c/hqdefault.jpg Your body runs on clocks you can’t see circadian rhythms that govern sleep, energy, metabolism, mood, and even longevity. In this episode of the ANEW Insight Podcast, Dr. Supatra Tovar sits down with a leading circadian science expert to reveal how timing your sleep, light exposure, and eating patterns can transform health in ways diet and exercise alone cannot. We explore why sleep is not passive rest but a nightly repair system that detoxifies the brain, resets hormones, and repairs tissues. You’ll learn how every organ—gut, skin, even hair—operates on its own internal schedule, and why ignoring these rhythms leads to fatigue, weight gain, mood imbalances, and chronic disease. This episode also unpacks the so-called “night owl” myth, showing how late-night habits are often driven by artificial light, stimulants, and lifestyle—not unchangeable genetics. With practical tools you can apply today, you’ll understand why consistent sleep, natural light exposure, and a defined eating window create a foundation for long-term vitality. ✨ Highlights from this episode include: 1. Why sleep is your body’s “operating theater” for repair and brain detox 2. The discovery of light-sensing proteins and their role in resetting the body clock 3. How circadian rhythms evolved for survival and still shape modern health 4. The truth about “night owls” and why most people are naturally aligned with morning light 5. Practical tips for sleep hygiene, light exposure, and daily rhythm alignment 6. A preview of Part Two: how eating within an 8–10 hour window can reset metabolism 🕒 Timestamps 00:00 – Welcome and introduction to circadian research 02:00 – How internal clocks influence health, weight, and aging 05:00 – From plants to humans: the biology of circadian rhythms 08:30 – Light-sensing proteins and the science of resetting sleep cycles 12:00 – Why circadian rhythms evolved as survival mechanisms 16:00 – Sleep as nightly repair: gut lining, skin, and brain detox 20:00 – The night owl myth explained through light and lifes https://www.youtube-nocookie.com/embed/_73-t1_Z9_c 742 2025-09-29T22:00:51.000Z 2026-10-22T18:54:02.090Z https://longevityharbor.com/en/watch/_8mJnPEsx-w NMN video description: NAD boosters and whether NMN is needed https://i.ytimg.com/vi/_8mJnPEsx-w/hqdefault.jpg The description lists NMN, NAD boosters, cell energy, longevity and biological age as topics, but gives no results, doses or evidence. https://www.youtube-nocookie.com/embed/_8mJnPEsx-w 107 2026-09-27T06:51:12.000Z 2026-10-23T00:37:29.739Z https://longevityharbor.com/de/watch/_8mJnPEsx-w NMN-Videobeschreibung: NAD-Booster und ob NMN nötig ist https://i.ytimg.com/vi/_8mJnPEsx-w/hqdefault.jpg Die Beschreibung nennt NMN, NAD-Booster, Zellenergie, Langlebigkeit und biologisches Alter als Themen, liefert aber keine Ergebnisse, Dosierungen oder Belege. https://www.youtube-nocookie.com/embed/_8mJnPEsx-w 107 2026-09-27T06:51:12.000Z 2026-10-23T00:37:29.739Z https://longevityharbor.com/en/watch/_9YFhwW-tfc Gute Gründe für eine gesunde und nachhaltige Ernährung im Alter https://i.ytimg.com/vi/_9YFhwW-tfc/hqdefault.jpg Aufzeichnung aus dem FORUM Volkshochschule. https://www.youtube-nocookie.com/embed/_9YFhwW-tfc 4453 2024-03-07T06:20:53.000Z 2026-10-22T19:04:43.903Z https://longevityharbor.com/de/watch/_9YFhwW-tfc Gute Gründe für eine gesunde und nachhaltige Ernährung im Alter https://i.ytimg.com/vi/_9YFhwW-tfc/hqdefault.jpg Aufzeichnung aus dem FORUM Volkshochschule. https://www.youtube-nocookie.com/embed/_9YFhwW-tfc 4453 2024-03-07T06:20:53.000Z 2026-10-22T19:04:43.903Z https://longevityharbor.com/en/watch/_9o-oD2sMV4 The Truth About mTOR, Autophagy and Longevity https://i.ytimg.com/vi/_9o-oD2sMV4/hqdefault.jpg ✅ Subscribe to my Channel: https://www.youtube.com/djockers In this video, I go through how to leverage and cycle between mTOR and autophagy. mTOR is a nutrient sensing pathway in the body that triggers cell growth and increased biomass. Autophagy signals cell repair and cellular resilience. Many longevity experts want to focus solely on autophagy, but it is important to have healthy cycling between mTOR and autophagy to preserve and maintain healthy muscle tissue while preventing protein damage and cellular senescence. To learn more read this article: https://drjockers.com/the-truth-about-mtor-autophagy-and-longevity/ ---------------------------------------------------------------------------------------------------------------------------------------- ✅ Subscribe to my Channel: https://www.youtube.com/djockers?sub_confirmation=1 ✅ Listen to my Podcast on Apple, and leave a review! Apple Podcast - https://podcasts.apple.com/us/podcast/dr-jockers-functional-nutrition/id1497791107 ✅ Listen on Spotify: Spotify - https://open.spotify.com/show/5l0LkYqW29ksV9Ut3hPuto AFFILIATE DISCLAIMER: Please see the link for our disclaimer policy for all of our videos on the Dr. Jockers YouTube Channel and Dr. Jockers Functional Nutrition Podcast. Thank you for supporting the channel! -- https://drjockers.com/drjockers-com-affiliate-disclosure/ protein,mTOR,autophagy,fasting,inflammation,inflammaging,aging,muscle,Dr David Jockers,dr david jockers,jockers,david,health,david jockers,drdavidjockers,the truth about mtor autophagy and longevity,truth about mtor,truth about autophagy,truth about longevity,longevity,mtor,The Truth About mTOR Autophagy and Longevity https://www.youtube-nocookie.com/embed/_9o-oD2sMV4 707 2024-06-09T11:00:34.000Z 2026-10-22T19:04:39.816Z https://longevityharbor.com/de/watch/_9o-oD2sMV4 The Truth About mTOR, Autophagy and Longevity https://i.ytimg.com/vi/_9o-oD2sMV4/hqdefault.jpg ✅ Subscribe to my Channel: https://www.youtube.com/djockers In this video, I go through how to leverage and cycle between mTOR and autophagy. mTOR is a nutrient sensing pathway in the body that triggers cell growth and increased biomass. Autophagy signals cell repair and cellular resilience. Many longevity experts want to focus solely on autophagy, but it is important to have healthy cycling between mTOR and autophagy to preserve and maintain healthy muscle tissue while preventing protein damage and cellular senescence. To learn more read this article: https://drjockers.com/the-truth-about-mtor-autophagy-and-longevity/ ---------------------------------------------------------------------------------------------------------------------------------------- ✅ Subscribe to my Channel: https://www.youtube.com/djockers?sub_confirmation=1 ✅ Listen to my Podcast on Apple, and leave a review! Apple Podcast - https://podcasts.apple.com/us/podcast/dr-jockers-functional-nutrition/id1497791107 ✅ Listen on Spotify: Spotify - https://open.spotify.com/show/5l0LkYqW29ksV9Ut3hPuto AFFILIATE DISCLAIMER: Please see the link for our disclaimer policy for all of our videos on the Dr. Jockers YouTube Channel and Dr. Jockers Functional Nutrition Podcast. Thank you for supporting the channel! -- https://drjockers.com/drjockers-com-affiliate-disclosure/ protein,mTOR,autophagy,fasting,inflammation,inflammaging,aging,muscle,Dr David Jockers,dr david jockers,jockers,david,health,david jockers,drdavidjockers,the truth about mtor autophagy and longevity,truth about mtor,truth about autophagy,truth about longevity,longevity,mtor,The Truth About mTOR Autophagy and Longevity https://www.youtube-nocookie.com/embed/_9o-oD2sMV4 707 2024-06-09T11:00:34.000Z 2026-10-22T19:04:39.816Z https://longevityharbor.com/en/watch/_Abtz2WpKfU Mikhail Blagosklonny on Rapamycin Longevity Series | mTOR drives age-related diseases https://i.ytimg.com/vi/_Abtz2WpKfU/hqdefault.jpg The world's leading Rapamycin researcher Mikhail Blagosklonny has a long background in cancer research and one important discovery he made around 2000 was that Rapamycin slowed down senescent cancer cells in different ways. After that step by step his interest in the longevity field increased and he developed the very interesting hyperfunction theory of aging. He has made a huge contribution in moving the Rapamycin longevity field forward and his research papers have impacted many people. For example, the Rapamycin physician Alan Green who thanks to these papers took the decision in 2017 to start prescribing Rapamycin off label. Today Alan Green has the biggest clinical experience in the area with more than 1200 patients. A lot of other physicians have after that also taken these steps and one of those are for example physician Peter Attia. 00:00 Intro 02:32 Current situation and mission 04:07 Why did Rapamycin not prevent his cancer? 06:33 He develops a new type of cancer treatment 08:32 Hyperfunction theory of age-related diseases 10:38 mTOR drives age-related diseases 13:00 Hyperfunction theory and the car analogy 17:20 Difference between new and old version of hyperfunction theory 19:58 Prediction based on hyperfunction theory 21:38 Rapamycin seems to work at any age 23:55 Rapamycin will not make you immortal 26:21 Rapamycin delays lung cancer in mice 27:44 Hyperfunction theory and hormesis 29:13 Rapamycin combination with fasting or calorie restriction 30:33 Rapamycin combination with Acarbose or low carb diet 31:40 Rapamycin combination with exercise 33:04 Exercise and longevity effect 36:10 mTOR sweet spot 38:44 Why do centenarians live a long life? 40:36 Theory of accumulation of molecular damage 44:04 Hyperfunction theory was initially rejected 47:47 Rapamycin research that is missing 51:44 Rapamycin and bacterial infection 53:30 Rapamycin side effect on longevity dose regime 55:50 Rapamycin and pseudo-diabetes 58:51 Rapamycin combination of Acarbose or low carb diet 1:00:09 Rapamycin and increase in li https://www.youtube-nocookie.com/embed/_Abtz2WpKfU 6128 2023-08-22T15:45:03.000Z 2026-10-22T17:43:41.752Z https://longevityharbor.com/de/watch/_Abtz2WpKfU Mikhail Blagosklonny on Rapamycin Longevity Series | mTOR drives age-related diseases https://i.ytimg.com/vi/_Abtz2WpKfU/hqdefault.jpg The world's leading Rapamycin researcher Mikhail Blagosklonny has a long background in cancer research and one important discovery he made around 2000 was that Rapamycin slowed down senescent cancer cells in different ways. After that step by step his interest in the longevity field increased and he developed the very interesting hyperfunction theory of aging. He has made a huge contribution in moving the Rapamycin longevity field forward and his research papers have impacted many people. For example, the Rapamycin physician Alan Green who thanks to these papers took the decision in 2017 to start prescribing Rapamycin off label. Today Alan Green has the biggest clinical experience in the area with more than 1200 patients. A lot of other physicians have after that also taken these steps and one of those are for example physician Peter Attia. 00:00 Intro 02:32 Current situation and mission 04:07 Why did Rapamycin not prevent his cancer? 06:33 He develops a new type of cancer treatment 08:32 Hyperfunction theory of age-related diseases 10:38 mTOR drives age-related diseases 13:00 Hyperfunction theory and the car analogy 17:20 Difference between new and old version of hyperfunction theory 19:58 Prediction based on hyperfunction theory 21:38 Rapamycin seems to work at any age 23:55 Rapamycin will not make you immortal 26:21 Rapamycin delays lung cancer in mice 27:44 Hyperfunction theory and hormesis 29:13 Rapamycin combination with fasting or calorie restriction 30:33 Rapamycin combination with Acarbose or low carb diet 31:40 Rapamycin combination with exercise 33:04 Exercise and longevity effect 36:10 mTOR sweet spot 38:44 Why do centenarians live a long life? 40:36 Theory of accumulation of molecular damage 44:04 Hyperfunction theory was initially rejected 47:47 Rapamycin research that is missing 51:44 Rapamycin and bacterial infection 53:30 Rapamycin side effect on longevity dose regime 55:50 Rapamycin and pseudo-diabetes 58:51 Rapamycin combination of Acarbose or low carb diet 1:00:09 Rapamycin and increase in li https://www.youtube-nocookie.com/embed/_Abtz2WpKfU 6128 2023-08-22T15:45:03.000Z 2026-10-22T17:43:41.752Z https://longevityharbor.com/en/watch/_BRw2d0qE_Q 5 MOST POWERFUL Anti-Aging Exercises – Scientifically Proven! https://i.ytimg.com/vi/_BRw2d0qE_Q/hqdefault.jpg 5 MOST POWERFUL ANTI-AGING EXERCISES – SCIENTIFICALLY PROVEN! Aging doesn’t have to mean losing strength, mobility, or independence! These 5 most powerful anti-aging exercises are scientifically proven to boost muscle strength, improve balance, protect joints, and keep you moving with ease—no matter your age. Whether you're in your 50s, 60s, or beyond, these exercises will help you stay strong, pain-free, and energized for life! 🏆 Why These Exercises? ✔ Build lean muscle to fight age-related muscle loss ✔ Improve balance & coordination to prevent falls ✔ Strengthen bones & joints for lifelong mobility ✔ Enhance posture and core stability for pain-free movement ✔ Boost metabolism, flexibility, and overall endurance 🧠 Backed by Science! Studies have proven that maintaining functional strength through resistance training can extend longevity and drastically reduce the risk of injury or mobility issues. If you want to move like you're 20, even in your 60s or 70s, these exercises are a must! 🔥 Who is this for? ✔ Men & women over 50 looking to stay fit, active, and independent ✔ Anyone struggling with joint stiffness, muscle loss, or poor balance ✔ People who want a simple yet effective anti-aging workout routine 💡 No Gym Needed! You can do these movements anywhere—at home, in a park, or even in your living room. The goal is staying strong, moving with ease, and living life without limitations. ⚡ Start Now! Don’t wait until weakness sets in. Train smart, age strong, and feel younger every day. Watch the full video and discover how to future-proof your body today! 🔔 Subscribe for More! Want more science-backed tips on staying strong and reversing aging naturally? Hit the subscribe button and turn on notifications so you never miss a game-changing video! #Healthpro #AntiAgingExercises #StayStrong #FitnessOver50 #Longevity #StrengthTraining #HealthyAging #WorkoutForSeniors #JointHealth #MetabolismBoost #FunctionalFitness #NoGymWorkout #MuscleStrength #AgeDefyingWorkout https://www.youtube-nocookie.com/embed/_BRw2d0qE_Q 1537 2025-02-19T19:07:01.000Z 2026-10-22T19:21:29.733Z https://longevityharbor.com/de/watch/_BRw2d0qE_Q 5 MOST POWERFUL Anti-Aging Exercises – Scientifically Proven! https://i.ytimg.com/vi/_BRw2d0qE_Q/hqdefault.jpg 5 MOST POWERFUL ANTI-AGING EXERCISES – SCIENTIFICALLY PROVEN! Aging doesn’t have to mean losing strength, mobility, or independence! These 5 most powerful anti-aging exercises are scientifically proven to boost muscle strength, improve balance, protect joints, and keep you moving with ease—no matter your age. Whether you're in your 50s, 60s, or beyond, these exercises will help you stay strong, pain-free, and energized for life! 🏆 Why These Exercises? ✔ Build lean muscle to fight age-related muscle loss ✔ Improve balance & coordination to prevent falls ✔ Strengthen bones & joints for lifelong mobility ✔ Enhance posture and core stability for pain-free movement ✔ Boost metabolism, flexibility, and overall endurance 🧠 Backed by Science! Studies have proven that maintaining functional strength through resistance training can extend longevity and drastically reduce the risk of injury or mobility issues. If you want to move like you're 20, even in your 60s or 70s, these exercises are a must! 🔥 Who is this for? ✔ Men & women over 50 looking to stay fit, active, and independent ✔ Anyone struggling with joint stiffness, muscle loss, or poor balance ✔ People who want a simple yet effective anti-aging workout routine 💡 No Gym Needed! You can do these movements anywhere—at home, in a park, or even in your living room. The goal is staying strong, moving with ease, and living life without limitations. ⚡ Start Now! Don’t wait until weakness sets in. Train smart, age strong, and feel younger every day. Watch the full video and discover how to future-proof your body today! 🔔 Subscribe for More! Want more science-backed tips on staying strong and reversing aging naturally? Hit the subscribe button and turn on notifications so you never miss a game-changing video! #Healthpro #AntiAgingExercises #StayStrong #FitnessOver50 #Longevity #StrengthTraining #HealthyAging #WorkoutForSeniors #JointHealth #MetabolismBoost #FunctionalFitness #NoGymWorkout #MuscleStrength #AgeDefyingWorkout https://www.youtube-nocookie.com/embed/_BRw2d0qE_Q 1537 2025-02-19T19:07:01.000Z 2026-10-22T19:21:29.733Z https://longevityharbor.com/en/watch/_FCLcGDz4vk What Is a Fasting Mimicking Diet? Benefits, Longevity & ProLon Explained | TrulyFit Podcast https://i.ytimg.com/vi/_FCLcGDz4vk/hqdefault.jpg In this episode of the TrulyFit Podcast, we explore the science behind the Fasting Mimicking Diet (FMD) and how it differs from traditional fasting. Registered Dietitian Renee Fitton, VP of B2B Sales & Growth at L-Nutra, joins Steve to break down the research, longevity benefits, and practical applications of fasting mimicking protocols. What is a fasting mimicking diet? How does it impact metabolism, cellular repair, and aging? And is ProLon worth it? We cover: • The difference between fasting and fasting mimicking • The science of longevity nutrition • Common misconceptions about fasting • How to ease into fasting safely • The ProLon 5-day protocol explained • The role of L-Nutra in clinical nutrition • Is diet information being gatekept? • Who should (and should NOT) try fasting The Fasting Mimicking Diet, developed by researchers at L-Nutra, is designed to trigger many of the biological benefits of fasting while still allowing nutrient intake. Their ProLon program has been studied for its potential effects on aging, inflammation, metabolic health, and cellular regeneration. Whether you’re interested in longevity, biohacking, intermittent fasting, or improving metabolic flexibility, this episode delivers science-backed insights. Connect with Renee Fitton: Instagram: @fittonnutrition Learn more about ProLon: https://prolonfmd.com Visit L-Nutra: https://l-nutra.com Timestamps: 00:00 Introduction 03:15 What Is a Fasting Mimicking Diet? 10:40 Fasting vs Fasting Mimicking 18:20 Longevity & Cellular Health 27:30 How ProLon Works 36:10 Who Should Avoid Fasting 45:00 Diet Industry & Information Gatekeeping 52:00 Final Takeaways #fasting #fastingmimickingdiet #longevity #nutritionpodcast #healthpodcast #prolon #lnutra #biohacking #wellness #trulyfitpodcast 🎧 Full episode + transcript: https://blog.trulyfit.app/renee-fitton-fasting-mimicking-diet/ https://www.youtube-nocookie.com/embed/_FCLcGDz4vk 2368 2025-10-20T01:20:07.000Z 2026-10-22T18:54:08.068Z https://longevityharbor.com/de/watch/_FCLcGDz4vk What Is a Fasting Mimicking Diet? Benefits, Longevity & ProLon Explained | TrulyFit Podcast https://i.ytimg.com/vi/_FCLcGDz4vk/hqdefault.jpg In this episode of the TrulyFit Podcast, we explore the science behind the Fasting Mimicking Diet (FMD) and how it differs from traditional fasting. Registered Dietitian Renee Fitton, VP of B2B Sales & Growth at L-Nutra, joins Steve to break down the research, longevity benefits, and practical applications of fasting mimicking protocols. What is a fasting mimicking diet? How does it impact metabolism, cellular repair, and aging? And is ProLon worth it? We cover: • The difference between fasting and fasting mimicking • The science of longevity nutrition • Common misconceptions about fasting • How to ease into fasting safely • The ProLon 5-day protocol explained • The role of L-Nutra in clinical nutrition • Is diet information being gatekept? • Who should (and should NOT) try fasting The Fasting Mimicking Diet, developed by researchers at L-Nutra, is designed to trigger many of the biological benefits of fasting while still allowing nutrient intake. Their ProLon program has been studied for its potential effects on aging, inflammation, metabolic health, and cellular regeneration. Whether you’re interested in longevity, biohacking, intermittent fasting, or improving metabolic flexibility, this episode delivers science-backed insights. Connect with Renee Fitton: Instagram: @fittonnutrition Learn more about ProLon: https://prolonfmd.com Visit L-Nutra: https://l-nutra.com Timestamps: 00:00 Introduction 03:15 What Is a Fasting Mimicking Diet? 10:40 Fasting vs Fasting Mimicking 18:20 Longevity & Cellular Health 27:30 How ProLon Works 36:10 Who Should Avoid Fasting 45:00 Diet Industry & Information Gatekeeping 52:00 Final Takeaways #fasting #fastingmimickingdiet #longevity #nutritionpodcast #healthpodcast #prolon #lnutra #biohacking #wellness #trulyfitpodcast 🎧 Full episode + transcript: https://blog.trulyfit.app/renee-fitton-fasting-mimicking-diet/ https://www.youtube-nocookie.com/embed/_FCLcGDz4vk 2368 2025-10-20T01:20:07.000Z 2026-10-22T18:54:08.068Z https://longevityharbor.com/en/watch/_M4b4sd7gF4 Video description on senescent 'zombie cells', aging and senolytics https://i.ytimg.com/vi/_M4b4sd7gF4/hqdefault.jpg The description says the video explains senescent cells that stop dividing but stay active, release inflammatory signals, and may contribute to aging, chronic disease and cancer progression; it also names senolytics and senomorphics. https://www.youtube-nocookie.com/embed/_M4b4sd7gF4 110 2026-06-07T02:16:15.000Z 2026-10-23T00:06:53.376Z https://longevityharbor.com/de/watch/_M4b4sd7gF4 Videobeschreibung zu seneszenten „Zombie-Zellen“, Altern und Senolytika https://i.ytimg.com/vi/_M4b4sd7gF4/hqdefault.jpg Laut Beschreibung erklärt das Video seneszente Zellen, die sich nicht mehr teilen, aber aktiv bleiben, entzündliche Signale abgeben und zu Altern, chronischen Krankheiten und Krebsfortschritt beitragen könnten; auch Senolytika und Senomorphika werden genannt. https://www.youtube-nocookie.com/embed/_M4b4sd7gF4 110 2026-06-07T02:16:15.000Z 2026-10-23T00:06:53.376Z https://longevityharbor.com/en/watch/_Nc5aYdcljM Gesunde Ernährung, Sport und Schlaf für eine höhere Lebenserwartung | Dr. Julia Fischer | ARD Gesund https://i.ytimg.com/vi/_Nc5aYdcljM/hqdefault.jpg Das Altern aufhalten oder zumindest verlangsamen - das verspricht der Longevity-Trend und belebt damit den Traum von ewiger Jugend wieder neu. Optimierte Ernährung und Sportprogramme, Supplements und verbesserter Schlaf sollen der Schlüssel dazu sein. Kann das funktionieren? Dr. Heinz-Wilhelm Esser geht der Frage nach, wie sich die eigene Lebenserwartung verlängern lässt - am liebsten bis 100 Jahre! Über Forschung, Selbstversuche und die Geheimtipps von Super-Agern spricht er mit Dr. Julia Fischer. 00:00 - Ich will hundert werden! 01:30 - Doc Esser über eigene Lebensweise 03:30 - Hier leben die Menschen am längsten 05:10 - Faktor Ernährung? 07:20 - Wie viel Bewegung? 10:25 - Eisbaden 12:30 - Schlaf und Schlafrhythmus 13:50 - Tracking-Apps 15:00 - Extrem-Tracking von Bryan Johnson 17:15 - Lässt sich der Tod verhindern? 18:20 - Ewiges Leben? 20:00 - Gesunde Essenspausen 21:00 - Anti-Aging-Medikament Metformin? 23:50 - Longevity spannend für Forschung "Doc Esser - Ich will hundert werden!" – hier geht's zur Doku: https://1.ard.de/docesser-100?ardg=yt Rezepte, Infos und mehr zur Doku mit Doc Esser: https://www1.wdr.de/fernsehen/doc-esser/doc-esser-gesundheitscheck-hundert-100.html Mehr über Longevity erfährst du hier: https://www.ndr.de/langesleben100.html Ein Film des NDR. Credit: NDR/Sebastian Reuther und picture alliance/Westend61/Roger Richter/Zoonar/Ruslan Huzau ___________________________________________________ ARD GESUND mit Dr. Julia Fischer ist ein YouTube-Kanal von ARD GESUND https://www.youtube-nocookie.com/embed/_Nc5aYdcljM 1565 2024-11-07T17:01:01.000Z 2026-10-22T18:43:10.840Z https://longevityharbor.com/de/watch/_Nc5aYdcljM Gesunde Ernährung, Sport und Schlaf für eine höhere Lebenserwartung | Dr. Julia Fischer | ARD Gesund https://i.ytimg.com/vi/_Nc5aYdcljM/hqdefault.jpg Das Altern aufhalten oder zumindest verlangsamen - das verspricht der Longevity-Trend und belebt damit den Traum von ewiger Jugend wieder neu. Optimierte Ernährung und Sportprogramme, Supplements und verbesserter Schlaf sollen der Schlüssel dazu sein. Kann das funktionieren? Dr. Heinz-Wilhelm Esser geht der Frage nach, wie sich die eigene Lebenserwartung verlängern lässt - am liebsten bis 100 Jahre! Über Forschung, Selbstversuche und die Geheimtipps von Super-Agern spricht er mit Dr. Julia Fischer. 00:00 - Ich will hundert werden! 01:30 - Doc Esser über eigene Lebensweise 03:30 - Hier leben die Menschen am längsten 05:10 - Faktor Ernährung? 07:20 - Wie viel Bewegung? 10:25 - Eisbaden 12:30 - Schlaf und Schlafrhythmus 13:50 - Tracking-Apps 15:00 - Extrem-Tracking von Bryan Johnson 17:15 - Lässt sich der Tod verhindern? 18:20 - Ewiges Leben? 20:00 - Gesunde Essenspausen 21:00 - Anti-Aging-Medikament Metformin? 23:50 - Longevity spannend für Forschung "Doc Esser - Ich will hundert werden!" – hier geht's zur Doku: https://1.ard.de/docesser-100?ardg=yt Rezepte, Infos und mehr zur Doku mit Doc Esser: https://www1.wdr.de/fernsehen/doc-esser/doc-esser-gesundheitscheck-hundert-100.html Mehr über Longevity erfährst du hier: https://www.ndr.de/langesleben100.html Ein Film des NDR. Credit: NDR/Sebastian Reuther und picture alliance/Westend61/Roger Richter/Zoonar/Ruslan Huzau ___________________________________________________ ARD GESUND mit Dr. Julia Fischer ist ein YouTube-Kanal von ARD GESUND https://www.youtube-nocookie.com/embed/_Nc5aYdcljM 1565 2024-11-07T17:01:01.000Z 2026-10-22T18:43:10.840Z https://longevityharbor.com/en/watch/_R4_2esa16c Fasting vs Cutting Calories, which is better? | New Trial https://i.ytimg.com/vi/_R4_2esa16c/hqdefault.jpg A new clinical trial pits Fasting against Calorie Counting for weight loss and metabolic parameters. Which strategy will come out on top? How do they affect body weight, cholesterol, glucose and blood pressure? A detailed look at the new trial. Subscribe for more free nutrition and health tips: https://bit.ly/2toMJ9u Connect with me: Facebook: https://www.facebook.com/DrGilCarvalho/ Twitter: https://twitter.com/NutritionMadeS3 Animations: Even Topland @toplandmedia References: 1-https://www.acpjournals.org/doi/10.7326/M23-0052 Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!. #NutritionMadeSimple #GilCarvalho 0:00 New trial pits Fasting vs Calorie Counting 1:51 The results 3:48 Weight maintenance 5:10 Weaknesses 6:40 Take-aways https://www.youtube-nocookie.com/embed/_R4_2esa16c 467 2023-07-31T13:00:21.000Z 2026-10-22T17:43:38.475Z https://longevityharbor.com/de/watch/_R4_2esa16c Fasting vs Cutting Calories, which is better? | New Trial https://i.ytimg.com/vi/_R4_2esa16c/hqdefault.jpg A new clinical trial pits Fasting against Calorie Counting for weight loss and metabolic parameters. Which strategy will come out on top? How do they affect body weight, cholesterol, glucose and blood pressure? A detailed look at the new trial. Subscribe for more free nutrition and health tips: https://bit.ly/2toMJ9u Connect with me: Facebook: https://www.facebook.com/DrGilCarvalho/ Twitter: https://twitter.com/NutritionMadeS3 Animations: Even Topland @toplandmedia References: 1-https://www.acpjournals.org/doi/10.7326/M23-0052 Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!. #NutritionMadeSimple #GilCarvalho 0:00 New trial pits Fasting vs Calorie Counting 1:51 The results 3:48 Weight maintenance 5:10 Weaknesses 6:40 Take-aways https://www.youtube-nocookie.com/embed/_R4_2esa16c 467 2023-07-31T13:00:21.000Z 2026-10-22T17:43:38.475Z https://longevityharbor.com/en/watch/_VanedCbMEg NMN vs. NR: The 2026 Verdict on the Best NAD+ Booster (Step 3) https://i.ytimg.com/vi/_VanedCbMEg/hqdefault.jpg *NMN vs. NR: The 2026 Verdict on the Best NAD+ Booster (Step 3)* A landmark January 2026 head-to-head human clinical trial has finally provided a definitive answer on the NMN vs. NR debate. If you are investing in your longevity, you need to understand how these precursors differ in blood-level elevation versus brain-tissue penetration. *MEDICAL DISCLAIMER:*This information is based on emerging clinical research and is intended for educational purposes only. It does not constitute medical advice, diagnosis, or treatment. NAD+ precursors are potent biological interventions. Always consult with a qualified healthcare professional before beginning any new supplementation or longevity regimen. *What you'll learn in this video:* 🔬 The biological difference between NMN and NR — and why it matters for YOUR cells. 📊 What the latest 2026 human trials reveal about NAD+ levels and tissue-specific bioavailability. 💊 A science-backed protocol for choosing the right precursor based on your age and biomarkers. 🧬 *OFFICIAL PROTOCOL DATABASE & VETTED SOURCES:* 👉 https://longevitylogiclabs.dub.link/Protocols (Access exact dosing, 2026 clinical data, and the lab-verified sources for this specific video.) 📄 The 2026 Head-to-Head Trial: Cuenoud B., et al. (2026). "Head-to-head comparison of NAD+ precursors NMN, NR, and nicotinamide in 65 healthy adults." Nature Metabolism. 🔗 https://bit.ly/Nature-NAD-Trial 🧠 The Norway Brain Study: "NR vs. NMN: Blood and Brain NAD+ Elevation in Parkinson’s Disease Research." (2026). Investigating blood-brain barrier penetration and cellular uptake. 🔗 https://bit.ly/Brain-NAD-Study 🧪 Bioavailability Analysis: Jinfiniti Clinical Review & MitoQ Science Journal. "NRK Pathway Analysis: Intracellular Bioavailability of NAD+ Precursors." 🔗 https://www.jinfiniti.com/nmn-and-nr/ ⏱ *TIMESTAMPS:* 0:00 Intro: The NAD+ Decline Problem 0:44 The Science: NMN vs. NR Pathways 2:22 The Protocol: Dosing & Stacking *SUPPORT THE CHANNEL:* If you found this research valuable, please Like and Subscribe t https://www.youtube-nocookie.com/embed/_VanedCbMEg 335 2026-05-08T13:28:06.000Z 2026-10-22T20:11:48.326Z https://longevityharbor.com/de/watch/_VanedCbMEg NMN vs. NR: The 2026 Verdict on the Best NAD+ Booster (Step 3) https://i.ytimg.com/vi/_VanedCbMEg/hqdefault.jpg *NMN vs. NR: The 2026 Verdict on the Best NAD+ Booster (Step 3)* A landmark January 2026 head-to-head human clinical trial has finally provided a definitive answer on the NMN vs. NR debate. If you are investing in your longevity, you need to understand how these precursors differ in blood-level elevation versus brain-tissue penetration. *MEDICAL DISCLAIMER:*This information is based on emerging clinical research and is intended for educational purposes only. It does not constitute medical advice, diagnosis, or treatment. NAD+ precursors are potent biological interventions. Always consult with a qualified healthcare professional before beginning any new supplementation or longevity regimen. *What you'll learn in this video:* 🔬 The biological difference between NMN and NR — and why it matters for YOUR cells. 📊 What the latest 2026 human trials reveal about NAD+ levels and tissue-specific bioavailability. 💊 A science-backed protocol for choosing the right precursor based on your age and biomarkers. 🧬 *OFFICIAL PROTOCOL DATABASE & VETTED SOURCES:* 👉 https://longevitylogiclabs.dub.link/Protocols (Access exact dosing, 2026 clinical data, and the lab-verified sources for this specific video.) 📄 The 2026 Head-to-Head Trial: Cuenoud B., et al. (2026). "Head-to-head comparison of NAD+ precursors NMN, NR, and nicotinamide in 65 healthy adults." Nature Metabolism. 🔗 https://bit.ly/Nature-NAD-Trial 🧠 The Norway Brain Study: "NR vs. NMN: Blood and Brain NAD+ Elevation in Parkinson’s Disease Research." (2026). Investigating blood-brain barrier penetration and cellular uptake. 🔗 https://bit.ly/Brain-NAD-Study 🧪 Bioavailability Analysis: Jinfiniti Clinical Review & MitoQ Science Journal. "NRK Pathway Analysis: Intracellular Bioavailability of NAD+ Precursors." 🔗 https://www.jinfiniti.com/nmn-and-nr/ ⏱ *TIMESTAMPS:* 0:00 Intro: The NAD+ Decline Problem 0:44 The Science: NMN vs. NR Pathways 2:22 The Protocol: Dosing & Stacking *SUPPORT THE CHANNEL:* If you found this research valuable, please Like and Subscribe t https://www.youtube-nocookie.com/embed/_VanedCbMEg 335 2026-05-08T13:28:06.000Z 2026-10-22T20:11:48.326Z https://longevityharbor.com/en/watch/_YUtzirzbVE Better sleep. More focus — Make your biology work for you (ft. Dr. Helen Burgess) https://i.ytimg.com/vi/_YUtzirzbVE/hqdefault.jpg Thank you Notion for sponsoring this video! Unlock AI for $10 per month → https://ntn.so/TheScienceofSelfCare 2025 Planner → https://ntn.so/scienceofselfscare2025 PATREON: https://www.patreon.com/c/thescienceofselfcare Let’s continue the convo 👆🤍 TIMESTAMPS Part 1 — 00:01;54 (daily productivity basics) - Part 2 — 00:12:44 (expert interview begins) 00:13:07 What do we risk when we compromise sleep? 00:14:23 Why is Dr. Burgess's research important? 00:17:17 What is are circadian rhythms? How are they different than sleep? 00:21:16 How do you measure someone's internal clock? 00:24:20 Are circadian tests done in complete darkness? 00:25:35 What's the deal with Chronotypes? 00:27:10 What is changing in our body over a 24 hour period? 00:29:17 How can we re-align to our natural internal rhythm? 00:32:24 Should you change your light exposure and melatonin supplementation at the same time? 00:34:27 Is there a certain amount of light we should aim for in the morning? 00:40:00 Is melatonin helpful? How much should we take? 00:45:00 Melatonin for anti-inflammatory properties? 00:48:40 Is there a danger with long-term melatonin use? 00:50:18 What is the relationship between circadian disturbance and mental health? 00:53:16 Should we all be moving our cycle earlier? 00:55:42 How can we support healthy circadian rhythms in this modern age? 00:58:17 What myths about sleep would you like to dispel? 01:00:15 Any last thoughts? Books Mentioned: WhenL The Scientific Secrets of Perfect Timing https://amzn.to/4hWNzBp Why We Sleep https://amzn.to/3Z9hEGs Re-timer Glasses (Version 2) https://amzn.to/40SvDSq FIND YOUR CHRONOTYPE You can take a look at this free chronotype questionnaire used for research: https://www.med.upenn.edu/cbti/assets/user-content/documents/Munich%20Chronotype%20Questionnaire%20(MCTQ).pdf CITATIONS Catalano, F., De Vito, F., Cassano, V., Fiorentino, T. V., Sciacqua, A., & Hribal, M. L. (2022). Circadian Clock Desynchronization and Insulin Resistance. International journal of environmental researc https://www.youtube-nocookie.com/embed/_YUtzirzbVE 3686 2024-11-18T02:48:45.000Z 2026-10-22T18:54:02.131Z https://longevityharbor.com/de/watch/_YUtzirzbVE Better sleep. More focus — Make your biology work for you (ft. Dr. Helen Burgess) https://i.ytimg.com/vi/_YUtzirzbVE/hqdefault.jpg Thank you Notion for sponsoring this video! Unlock AI for $10 per month → https://ntn.so/TheScienceofSelfCare 2025 Planner → https://ntn.so/scienceofselfscare2025 PATREON: https://www.patreon.com/c/thescienceofselfcare Let’s continue the convo 👆🤍 TIMESTAMPS Part 1 — 00:01;54 (daily productivity basics) - Part 2 — 00:12:44 (expert interview begins) 00:13:07 What do we risk when we compromise sleep? 00:14:23 Why is Dr. Burgess's research important? 00:17:17 What is are circadian rhythms? How are they different than sleep? 00:21:16 How do you measure someone's internal clock? 00:24:20 Are circadian tests done in complete darkness? 00:25:35 What's the deal with Chronotypes? 00:27:10 What is changing in our body over a 24 hour period? 00:29:17 How can we re-align to our natural internal rhythm? 00:32:24 Should you change your light exposure and melatonin supplementation at the same time? 00:34:27 Is there a certain amount of light we should aim for in the morning? 00:40:00 Is melatonin helpful? How much should we take? 00:45:00 Melatonin for anti-inflammatory properties? 00:48:40 Is there a danger with long-term melatonin use? 00:50:18 What is the relationship between circadian disturbance and mental health? 00:53:16 Should we all be moving our cycle earlier? 00:55:42 How can we support healthy circadian rhythms in this modern age? 00:58:17 What myths about sleep would you like to dispel? 01:00:15 Any last thoughts? Books Mentioned: WhenL The Scientific Secrets of Perfect Timing https://amzn.to/4hWNzBp Why We Sleep https://amzn.to/3Z9hEGs Re-timer Glasses (Version 2) https://amzn.to/40SvDSq FIND YOUR CHRONOTYPE You can take a look at this free chronotype questionnaire used for research: https://www.med.upenn.edu/cbti/assets/user-content/documents/Munich%20Chronotype%20Questionnaire%20(MCTQ).pdf CITATIONS Catalano, F., De Vito, F., Cassano, V., Fiorentino, T. V., Sciacqua, A., & Hribal, M. L. (2022). Circadian Clock Desynchronization and Insulin Resistance. International journal of environmental researc https://www.youtube-nocookie.com/embed/_YUtzirzbVE 3686 2024-11-18T02:48:45.000Z 2026-10-22T18:54:02.131Z https://longevityharbor.com/en/watch/_Y_-0hcQs2Y Video description: 66-year-old Yant Morrison on diet, training and discipline https://i.ytimg.com/vi/_Y_-0hcQs2Y/hqdefault.jpg The description presents Yant Morrison, 66, as looking younger and names protein-rich food, vegetables, regular training without a gym, strong muscles and arms, and discipline as his habits. It offers no measurements or study results. https://www.youtube-nocookie.com/embed/_Y_-0hcQs2Y 505 2026-09-23T16:55:22.000Z 2026-10-22T21:55:49.670Z https://longevityharbor.com/de/watch/_Y_-0hcQs2Y Videobeschreibung: Der 66-jährige Yant Morrison über Ernährung, Training und Disziplin https://i.ytimg.com/vi/_Y_-0hcQs2Y/hqdefault.jpg Die Beschreibung stellt den 66-jährigen Yant Morrison als jünger wirkend vor und nennt eiweißreiche Ernährung, Gemüse, regelmäßiges Training ohne Fitnessstudio, starke Muskeln und Arme sowie Disziplin als seine Gewohnheiten. Messwerte oder Studienergebnisse enthält sie nicht. https://www.youtube-nocookie.com/embed/_Y_-0hcQs2Y 505 2026-09-23T16:55:22.000Z 2026-10-22T21:55:49.670Z https://longevityharbor.com/en/watch/__qqklcEPw0 Video description: rapamycin, mTOR and lifespan claims in animals https://i.ytimg.com/vi/__qqklcEPw0/hqdefault.jpg The description says rapamycin targets mTOR and that animal studies show longer lifespan and stronger immune function, with a claimed effect of up to 20% similar to extreme calorie restriction. It also says safety, dosage and expert disagreement remain debated; the video itself was not reviewed. https://www.youtube-nocookie.com/embed/__qqklcEPw0 202 2025-12-04T15:36:10.000Z 2026-10-23T03:22:13.751Z https://longevityharbor.com/de/watch/__qqklcEPw0 Videobeschreibung: Rapamycin, mTOR und Lebensspannen-Aussagen bei Tieren https://i.ytimg.com/vi/__qqklcEPw0/hqdefault.jpg Die Beschreibung sagt, Rapamycin wirke auf mTOR, und Tierstudien zeigten eine längere Lebensspanne und stärkere Immunfunktion, mit einem behaupteten Effekt von bis zu 20% ähnlich extremer Kalorienrestriktion. Sicherheit, Dosierung und Expertenstreit blieben umstritten; das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/__qqklcEPw0 202 2025-12-04T15:36:10.000Z 2026-10-23T03:22:13.751Z https://longevityharbor.com/en/watch/_c4KKf36WyY Video description: Can exercise reverse aging? Strength, nutrition and sleep claims https://i.ytimg.com/vi/_c4KKf36WyY/hqdefault.jpg This YouTube description says the video explores whether strength training, regular exercise, proper nutrition and quality sleep may help people stay stronger and healthier as they age, and what research says about biological aging. No results are reported in the description. https://www.youtube-nocookie.com/embed/_c4KKf36WyY 334 2026-10-21T14:09:21.000Z 2026-10-22T19:48:09.292Z https://longevityharbor.com/de/watch/_c4KKf36WyY Videobeschreibung: Kann Sport das Altern umkehren? Aussagen zu Kraft, Ernährung und Schlaf https://i.ytimg.com/vi/_c4KKf36WyY/hqdefault.jpg Diese YouTube-Beschreibung sagt, das Video untersuche, ob Krafttraining, regelmäßige Bewegung, richtige Ernährung und guter Schlaf Menschen helfen können, im Alter stärker und gesünder zu bleiben, und was die Forschung zum biologischen Altern sagt. In der Beschreibung werden keine Ergebnisse berichtet. https://www.youtube-nocookie.com/embed/_c4KKf36WyY 334 2026-10-21T14:09:21.000Z 2026-10-22T19:48:09.292Z https://longevityharbor.com/en/watch/_dOofH4PC9w Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration — can we change the pace? https://i.ytimg.com/vi/_dOofH4PC9w/hqdefault.jpg Morgan Levine, Ph.D., developed the phenotypic aging clock called PhenoAge and is a Founding Principal Investigator at Altos Labs, a biotech company that seeks to understand the mechanisms that drive the aging process and age-related diseases with the hope of identifying possible interventions. Additionally, Dr. Levine is an assistant professor of pathology at the Yale University School of Medicine, where her research focuses on the science of biological aging. Dr. Levine completed a postdoctoral fellowship with previous guest Dr. Steve Horvath, a pioneer in the field of epigenetic clocks. EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/morgan-levine?utm_source=youtube&utm_medium=youtube&utm_campaign=levine_interview "True Age: Cutting-Edge Research to Help Turn Back the Clock" Book: https://www.amazon.com/True-Age-Cutting-Edge-Research-Clock/dp/0593329287 Dr. Morgan Levine on Instagram: https://www.instagram.com/dr.morganlevine/ Dr. Morgan Levine on Twitter: https://www.twitter.com/drmorganlevine PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=levine_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/072-morgan-levine-phd-on-phenoage-and-the-epigenetics/id818198322?i=100055736838 Spotify: https://open.spotify.com/show/5QjpaU0o1Q2MkVZwwG3y7d Full interview playlist: https://www.youtube.com/playlist?list=PLJEEAVzHu9KzgkQbe2Thh35VU-HCiId_s Clips playlist: https://www.youtube.com/playlist?list=PLrGxo-5Uw8gI9-1IStYEvNxVukKxZBlmi CHAPTERS: 00:01:19 - What is aging? 00:03:20 - Why biological aging matters to scientists 00:04:45 - Hallmarks of aging 00:05:24 - What are the drivers of aging? 00:06:58 - What CpG methylation says about aging 00:08:59 - The advantage of epigenetic clocks in research 00:10:12 - New generation epigenetic clocks: GrimAge and PhenoAge 00:11:51 - Clinical biomarkers vs. epigenetic clocks 00:12:50 - Differences in aging between organ systems 00:16:47 - Do some people age faster https://www.youtube-nocookie.com/embed/_dOofH4PC9w 4854 2022-04-12T15:00:10.000Z 2026-10-22T17:43:35.255Z https://longevityharbor.com/de/watch/_dOofH4PC9w Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration — can we change the pace? https://i.ytimg.com/vi/_dOofH4PC9w/hqdefault.jpg Morgan Levine, Ph.D., developed the phenotypic aging clock called PhenoAge and is a Founding Principal Investigator at Altos Labs, a biotech company that seeks to understand the mechanisms that drive the aging process and age-related diseases with the hope of identifying possible interventions. Additionally, Dr. Levine is an assistant professor of pathology at the Yale University School of Medicine, where her research focuses on the science of biological aging. Dr. Levine completed a postdoctoral fellowship with previous guest Dr. Steve Horvath, a pioneer in the field of epigenetic clocks. EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/morgan-levine?utm_source=youtube&utm_medium=youtube&utm_campaign=levine_interview "True Age: Cutting-Edge Research to Help Turn Back the Clock" Book: https://www.amazon.com/True-Age-Cutting-Edge-Research-Clock/dp/0593329287 Dr. Morgan Levine on Instagram: https://www.instagram.com/dr.morganlevine/ Dr. Morgan Levine on Twitter: https://www.twitter.com/drmorganlevine PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=levine_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/072-morgan-levine-phd-on-phenoage-and-the-epigenetics/id818198322?i=100055736838 Spotify: https://open.spotify.com/show/5QjpaU0o1Q2MkVZwwG3y7d Full interview playlist: https://www.youtube.com/playlist?list=PLJEEAVzHu9KzgkQbe2Thh35VU-HCiId_s Clips playlist: https://www.youtube.com/playlist?list=PLrGxo-5Uw8gI9-1IStYEvNxVukKxZBlmi CHAPTERS: 00:01:19 - What is aging? 00:03:20 - Why biological aging matters to scientists 00:04:45 - Hallmarks of aging 00:05:24 - What are the drivers of aging? 00:06:58 - What CpG methylation says about aging 00:08:59 - The advantage of epigenetic clocks in research 00:10:12 - New generation epigenetic clocks: GrimAge and PhenoAge 00:11:51 - Clinical biomarkers vs. epigenetic clocks 00:12:50 - Differences in aging between organ systems 00:16:47 - Do some people age faster https://www.youtube-nocookie.com/embed/_dOofH4PC9w 4854 2022-04-12T15:00:10.000Z 2026-10-22T17:43:35.255Z https://longevityharbor.com/en/watch/_eTQoD3s4vI Calorie Restriction & Longevity https://i.ytimg.com/vi/_eTQoD3s4vI/hqdefault.jpg Want to live to 120 and stay healthy the whole way? In this Longevity Series Part 2, we explore the science behind calorie restriction, one of the most studied and documented strategies for extending lifespan. Research on caloric restriction in animals—from nematodes to mice—shows significant lifespan extension. But does it work the same way in humans? ► Boost your body's natural repair system! Try STEMREGEN® Release 👉https://www.stemregen.co/products/release In this video, we break down: ✅ How calorie restriction influences aging and longevity ✅ The best approach for humans (30% calorie reduction, time-restricted eating) ✅ Why reducing sugar and carbs (not protein) is crucial for longevity ✅ How fasting and calorie restriction impact metabolic health and disease prevention Learn how to optimize your diet for longevity, prevent age-related diseases, and unlock your body's natural ability to extend its healthspan. If you're interested in biohacking, anti-aging, fasting, and longevity science, this video is for you! 🔔 Subscribe for more longevity and biohacking insights! #CalorieRestriction #Longevity #AntiAging #Biohacking #StemCells #Fasting #HealthOptimization #LifespanExtension https://www.youtube-nocookie.com/embed/_eTQoD3s4vI 170 2025-03-27T18:28:42.000Z 2026-10-22T18:54:08.088Z https://longevityharbor.com/de/watch/_eTQoD3s4vI Calorie Restriction & Longevity https://i.ytimg.com/vi/_eTQoD3s4vI/hqdefault.jpg Want to live to 120 and stay healthy the whole way? In this Longevity Series Part 2, we explore the science behind calorie restriction, one of the most studied and documented strategies for extending lifespan. Research on caloric restriction in animals—from nematodes to mice—shows significant lifespan extension. But does it work the same way in humans? ► Boost your body's natural repair system! Try STEMREGEN® Release 👉https://www.stemregen.co/products/release In this video, we break down: ✅ How calorie restriction influences aging and longevity ✅ The best approach for humans (30% calorie reduction, time-restricted eating) ✅ Why reducing sugar and carbs (not protein) is crucial for longevity ✅ How fasting and calorie restriction impact metabolic health and disease prevention Learn how to optimize your diet for longevity, prevent age-related diseases, and unlock your body's natural ability to extend its healthspan. If you're interested in biohacking, anti-aging, fasting, and longevity science, this video is for you! 🔔 Subscribe for more longevity and biohacking insights! #CalorieRestriction #Longevity #AntiAging #Biohacking #StemCells #Fasting #HealthOptimization #LifespanExtension https://www.youtube-nocookie.com/embed/_eTQoD3s4vI 170 2025-03-27T18:28:42.000Z 2026-10-22T18:54:08.088Z https://longevityharbor.com/en/watch/_fwN-6C5NWk Dein biologisches Alter erfahren? So geht's! Interview mit Epigenetiker Prof. Moshe Szyf https://i.ytimg.com/vi/_fwN-6C5NWk/hqdefault.jpg In diesem Video lernt ihr, wie ihr euer biologisches Alter messen könnt! Denn unser chronologisches Alter - also das, was in unserem Ausweis steht, hat oft nichts mit unserem biologischen Alter zu tun - dem wirklichen Zustand unserer Zellen, unseres Gewebes etc. Ihr lernt heute, wie die Horvath Clock funktioniert, die berühmteste eigenetische Uhr der Welt (Steve Horvath ist ein Freund von David Sinclair und seine Uhr wird oft in Studien zu Verjüngungstherapien eingesetzt), und welche eigenetische Uhr ihr Zuhause benutzen könnt, um euer biologisches Alter zu erfahren. Ich interviewe Prof. Moshe Szyf aus Kanada, er ist einer der weltweit führenden Epigenetiker, und er erzählt euch, welche Faktoren nach seiner jahrelangen Longevity-Forschung unsere biologische Uhr verlangsamen und welche sie beschleunigen. Ihr lernt wie immer viele neue Dinge, die ihr in euren Alltag einbauen könnt. Viel Spaß! :) #BiologischesAlter #Alterstest #MosheSzyf Werbung: Die nachfolgenden Produkt-Links sind Affiliate Links (*): Wenn du über diese Links etwas kaufst, erhalte ich eine kleine Vergütung, für dich entstehen dabei keinerlei Mehrkosten. Du kannst natürlich die Sachen auch woanders kaufen, ganz wie du magst. Danke, dass du meinen Kanal unterstützt. :) Disclaimer: Bitte sprecht unbedingt mit eurem Arzt, bevor ihr in Erwägung zieht, Supplements auszuprobieren - ich bin kein Arzt und gebe keine medizinischen Ratschläge. 💊Supplements, die ich nehme, um Altern aufzuhalten - auf alles 15% Rabatt mit dem Code "ANASTASIA":💊 * NMN: in EU hergestelltes Longevir NMN: https://avea-life.com/de/products/nmn?aff=ANASTASIARASTOR (1 Kapsel morgens mit Wasser) * Mein Longevity Bundle / alle Longevity-Wirkstoffe in einem Bundle: NMN, TMG, Trans-Resveratrol, Coenzym Q10, Pterostilben, Apigenin, Kollagen: https://avea-life.com/de/products/longevity-bundle?country=DE&utm_source=YOUTUBE&utm_medium=INFLUENCER&utm_campaign=YT-DACH-INFL-PURC-COLL-ANASTASIA-14462544&utm_term=BROD-YTD_-DACH-LONG-COLL&utm_content=COLL-VID-UGCC-HOME-BENE-D15X (jeden https://www.youtube-nocookie.com/embed/_fwN-6C5NWk 1656 2021-11-09T15:30:04.000Z 2026-10-22T17:11:30.664Z https://longevityharbor.com/de/watch/_fwN-6C5NWk Dein biologisches Alter erfahren? So geht's! Interview mit Epigenetiker Prof. Moshe Szyf https://i.ytimg.com/vi/_fwN-6C5NWk/hqdefault.jpg In diesem Video lernt ihr, wie ihr euer biologisches Alter messen könnt! Denn unser chronologisches Alter - also das, was in unserem Ausweis steht, hat oft nichts mit unserem biologischen Alter zu tun - dem wirklichen Zustand unserer Zellen, unseres Gewebes etc. Ihr lernt heute, wie die Horvath Clock funktioniert, die berühmteste eigenetische Uhr der Welt (Steve Horvath ist ein Freund von David Sinclair und seine Uhr wird oft in Studien zu Verjüngungstherapien eingesetzt), und welche eigenetische Uhr ihr Zuhause benutzen könnt, um euer biologisches Alter zu erfahren. Ich interviewe Prof. Moshe Szyf aus Kanada, er ist einer der weltweit führenden Epigenetiker, und er erzählt euch, welche Faktoren nach seiner jahrelangen Longevity-Forschung unsere biologische Uhr verlangsamen und welche sie beschleunigen. Ihr lernt wie immer viele neue Dinge, die ihr in euren Alltag einbauen könnt. Viel Spaß! :) #BiologischesAlter #Alterstest #MosheSzyf Werbung: Die nachfolgenden Produkt-Links sind Affiliate Links (*): Wenn du über diese Links etwas kaufst, erhalte ich eine kleine Vergütung, für dich entstehen dabei keinerlei Mehrkosten. Du kannst natürlich die Sachen auch woanders kaufen, ganz wie du magst. Danke, dass du meinen Kanal unterstützt. :) Disclaimer: Bitte sprecht unbedingt mit eurem Arzt, bevor ihr in Erwägung zieht, Supplements auszuprobieren - ich bin kein Arzt und gebe keine medizinischen Ratschläge. 💊Supplements, die ich nehme, um Altern aufzuhalten - auf alles 15% Rabatt mit dem Code "ANASTASIA":💊 * NMN: in EU hergestelltes Longevir NMN: https://avea-life.com/de/products/nmn?aff=ANASTASIARASTOR (1 Kapsel morgens mit Wasser) * Mein Longevity Bundle / alle Longevity-Wirkstoffe in einem Bundle: NMN, TMG, Trans-Resveratrol, Coenzym Q10, Pterostilben, Apigenin, Kollagen: https://avea-life.com/de/products/longevity-bundle?country=DE&utm_source=YOUTUBE&utm_medium=INFLUENCER&utm_campaign=YT-DACH-INFL-PURC-COLL-ANASTASIA-14462544&utm_term=BROD-YTD_-DACH-LONG-COLL&utm_content=COLL-VID-UGCC-HOME-BENE-D15X (jeden https://www.youtube-nocookie.com/embed/_fwN-6C5NWk 1656 2021-11-09T15:30:04.000Z 2026-10-22T17:11:30.664Z https://longevityharbor.com/en/watch/_il_U7lH8wc Epigenetic Aging: How old is your DNA? https://i.ytimg.com/vi/_il_U7lH8wc/hqdefault.jpg Dr. Steve Horvath, a professor of genetics and biostatistics at UCLA, has found a way to measure biological aging – a type of "clock" – based on the methylation pattern of an organism's genome. Methylations are biochemical processes that modify the activity of a DNA segment without changing its sequence – a type of epigenetic change. This video primer explains the basics of epigenetic clocks, the topic of our interview with Dr. Steve Horvath, coming soon! Get the show notes here: https://www.foundmyfitness.com/episodes/epigenetic-clock/ Episode chapters: 00:00 - Biological vs chronological age 00:40 - Estimating biological age with epigenetics 01:17 - The Horvath clock 01:54 - The GrimAge clock 02:19 - Altering biological age About FoundMyFitness: Rhonda Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, and St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer, and nutrition. It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach. Learn more about Dr. Rhonda Patrick and her mission for FoundMyFitness at www.foundmyfitness.com This episode was fiscally sponsored through The Film Collaborative and a grant from a generous anonymous donor. https://www.thefilmcollaborative.org #Epigenetics #Longevity #DNAMethylation https://www.youtube-nocookie.com/embed/_il_U7lH8wc 226 2020-12-15T18:42:27.000Z 2026-10-22T17:43:35.144Z https://longevityharbor.com/de/watch/_il_U7lH8wc Epigenetic Aging: How old is your DNA? https://i.ytimg.com/vi/_il_U7lH8wc/hqdefault.jpg Dr. Steve Horvath, a professor of genetics and biostatistics at UCLA, has found a way to measure biological aging – a type of "clock" – based on the methylation pattern of an organism's genome. Methylations are biochemical processes that modify the activity of a DNA segment without changing its sequence – a type of epigenetic change. This video primer explains the basics of epigenetic clocks, the topic of our interview with Dr. Steve Horvath, coming soon! Get the show notes here: https://www.foundmyfitness.com/episodes/epigenetic-clock/ Episode chapters: 00:00 - Biological vs chronological age 00:40 - Estimating biological age with epigenetics 01:17 - The Horvath clock 01:54 - The GrimAge clock 02:19 - Altering biological age About FoundMyFitness: Rhonda Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, and St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer, and nutrition. It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach. Learn more about Dr. Rhonda Patrick and her mission for FoundMyFitness at www.foundmyfitness.com This episode was fiscally sponsored through The Film Collaborative and a grant from a generous anonymous donor. https://www.thefilmcollaborative.org #Epigenetics #Longevity #DNAMethylation https://www.youtube-nocookie.com/embed/_il_U7lH8wc 226 2020-12-15T18:42:27.000Z 2026-10-22T17:43:35.144Z https://longevityharbor.com/en/watch/_muI9sI1riU Video description: fermented foods, gut microbiome and healthy ageing https://i.ytimg.com/vi/_muI9sI1riU/hqdefault.jpg The description says the video covers how fermented foods may support gut microbial diversity, butyrate and gut barrier health, and how gut health is linked to ageing; it cites a human randomised trial on fermented foods and inflammation. https://www.youtube-nocookie.com/embed/_muI9sI1riU 664 2026-09-15T12:45:09.000Z 2026-10-22T22:11:46.595Z https://longevityharbor.com/de/watch/_muI9sI1riU Videobeschreibung: fermentierte Lebensmittel, Darmmikrobiom und gesundes Altern https://i.ytimg.com/vi/_muI9sI1riU/hqdefault.jpg Laut Beschreibung behandelt das Video, wie fermentierte Lebensmittel die Vielfalt der Darmmikroben, Butyrat und die Darmbarriere unterstützen könnten und wie Darmgesundheit mit Altern zusammenhängt; es nennt eine randomisierte Humanstudie zu fermentierten Lebensmitteln und Entzündung. https://www.youtube-nocookie.com/embed/_muI9sI1riU 664 2026-09-15T12:45:09.000Z 2026-10-22T22:11:46.595Z https://longevityharbor.com/en/watch/_nCkA-qiXBg HOW TO AGE REVERSE WITH AUTOPHAGY|THREE POWERFUL WAYS TO INCREASE AUTOPHAGY https://i.ytimg.com/vi/_nCkA-qiXBg/hqdefault.jpg Your dermatologist will never tell you this because most have never even heard of it. ‎Yet it’s the most powerful, natural way to reverse aging from the inside out. ‎ ‎In this video, I uncover the science of autophagy your body’s built-in cellular renewal system that clears away damaged cells, stimulates collagen, and restores youthful function to your skin, brain, and body. ‎ ‎You’ll learn: ‎• What autophagy is and why it’s the foundation of real anti-aging ‎• How fasting triggers deep cellular repair and why women need a different fasting window than men ‎• How to enhance autophagy safely through lifestyle, HIIT training, and sleep ‎• The nutrients that extend autophagy  including Spermidine, Omega-3, and NMN ‎ ‎✨ Featured in this video: ‎Wild Foods Omega-3: https://thebeautydoctrine.com/products/wild-foods-omega-3-fish-oil-capsules?_pos=3&_psq=Omega+&_ss=e&_v=1.0 ‎ ‎Agent Nateur Calm Beauty (Spermidine + Taurine): https://thebeautydoctrine.com/products/agent-nateur-calm-beauty-spermidine-taurine-daily-supplement?_pos=1&_psq=Calm+b&_ss=e&_v=1.0 ‎ ‎Neurogan NMN + Resveratrol:https://thebeautydoctrine.com/products/nmn-resveratrol-capsules?_pos=1&_psq=NMN&_ss=e&_v=1.0 ‎ ‎Neurogan Spermidine Complex: https://thebeautydoctrine.com/products/liposomal-spermidin-capsules?_pos=2&_psq=Spermidine+&_ss=e&_v=1.0 ‎ HigerDoes Sauna blanket https://go.shopmy.us/p-226211 ( Use code; NADIA15 FOR 15% OFF) ‎💡 Learn more at: thebeautydoctrine.com ‎ ‎ ‎References ‎Frontiers in Endocrinology (2018): Hallmarks of Aging  An Autophagic Perspective ‎PMC 2022: Role of Autophagy in Aging: The Good, The Bad, and The Ugly ‎MDPI 2023: Molecular Mechanisms of Autophagy Decline During Aging ‎Frontiers in Cell & Developmental Biology (2021): Autophagy and Aging in Skeletal Muscle and Brain ‎ ‎#autophagy #antiaging #fasting #longevity #neuroganhealth #nmn #repair #tbd #trending #yt #agentnateur ‎ https://www.youtube-nocookie.com/embed/_nCkA-qiXBg 623 2025-11-12T22:30:11.000Z 2026-10-22T19:32:33.523Z https://longevityharbor.com/de/watch/_nCkA-qiXBg HOW TO AGE REVERSE WITH AUTOPHAGY|THREE POWERFUL WAYS TO INCREASE AUTOPHAGY https://i.ytimg.com/vi/_nCkA-qiXBg/hqdefault.jpg Your dermatologist will never tell you this because most have never even heard of it. ‎Yet it’s the most powerful, natural way to reverse aging from the inside out. ‎ ‎In this video, I uncover the science of autophagy your body’s built-in cellular renewal system that clears away damaged cells, stimulates collagen, and restores youthful function to your skin, brain, and body. ‎ ‎You’ll learn: ‎• What autophagy is and why it’s the foundation of real anti-aging ‎• How fasting triggers deep cellular repair and why women need a different fasting window than men ‎• How to enhance autophagy safely through lifestyle, HIIT training, and sleep ‎• The nutrients that extend autophagy  including Spermidine, Omega-3, and NMN ‎ ‎✨ Featured in this video: ‎Wild Foods Omega-3: https://thebeautydoctrine.com/products/wild-foods-omega-3-fish-oil-capsules?_pos=3&_psq=Omega+&_ss=e&_v=1.0 ‎ ‎Agent Nateur Calm Beauty (Spermidine + Taurine): https://thebeautydoctrine.com/products/agent-nateur-calm-beauty-spermidine-taurine-daily-supplement?_pos=1&_psq=Calm+b&_ss=e&_v=1.0 ‎ ‎Neurogan NMN + Resveratrol:https://thebeautydoctrine.com/products/nmn-resveratrol-capsules?_pos=1&_psq=NMN&_ss=e&_v=1.0 ‎ ‎Neurogan Spermidine Complex: https://thebeautydoctrine.com/products/liposomal-spermidin-capsules?_pos=2&_psq=Spermidine+&_ss=e&_v=1.0 ‎ HigerDoes Sauna blanket https://go.shopmy.us/p-226211 ( Use code; NADIA15 FOR 15% OFF) ‎💡 Learn more at: thebeautydoctrine.com ‎ ‎ ‎References ‎Frontiers in Endocrinology (2018): Hallmarks of Aging  An Autophagic Perspective ‎PMC 2022: Role of Autophagy in Aging: The Good, The Bad, and The Ugly ‎MDPI 2023: Molecular Mechanisms of Autophagy Decline During Aging ‎Frontiers in Cell & Developmental Biology (2021): Autophagy and Aging in Skeletal Muscle and Brain ‎ ‎#autophagy #antiaging #fasting #longevity #neuroganhealth #nmn #repair #tbd #trending #yt #agentnateur ‎ https://www.youtube-nocookie.com/embed/_nCkA-qiXBg 623 2025-11-12T22:30:11.000Z 2026-10-22T19:32:33.523Z https://longevityharbor.com/en/watch/_pETxg-49Z8 Reprogrammed donor cells scored younger on a DNA age clock: a lab study, not a treatment https://i.ytimg.com/vi/_pETxg-49Z8/hqdefault.jpg In a laboratory study, University of Bonn researchers reprogrammed blood-forming precursor cells from donors of different ages, including people over 100, into neural stem cells. Their DNA-based age estimates fell, with changes unfolding over weeks. This is a cell study, not a treatment; safety and whole-body effects remain open. https://www.youtube-nocookie.com/embed/_pETxg-49Z8 109 2026-10-15T11:32:29.000Z 2026-10-22T19:53:15.579Z https://longevityharbor.com/de/watch/_pETxg-49Z8 Umprogrammierte Spenderzellen zeigten sich jünger auf einer DNA-Altersuhr: eine Laborstudie, keine B https://i.ytimg.com/vi/_pETxg-49Z8/hqdefault.jpg In einer Laborstudie programmierten Forschende der Universität Bonn blutbildende Vorläuferzellen von Spendern verschiedenen Alters, darunter Menschen über 100, zu neuralen Stammzellen um. Ihre DNA-basierten Altersschätzungen sanken, die Veränderungen liefen über Wochen. Das ist eine Zellstudie, keine Behandlung; Sicherheit und Wirkung auf den ganzen Körper bleiben offen. https://www.youtube-nocookie.com/embed/_pETxg-49Z8 109 2026-10-15T11:32:29.000Z 2026-10-22T19:53:15.579Z https://longevityharbor.com/en/watch/_pYE6u_nMpA Video description: Sinclair's epigenetic rejuvenation claims explained https://i.ytimg.com/vi/_pYE6u_nMpA/hqdefault.jpg The description presents David Sinclair's epigenetic rejuvenation ideas: methyl-group tags drift with age, clocks such as GrimAge and DunedinPACE measure biological age, and Yamanaka factors partially reprogram cells. It also lists sleep, fasting, Mediterranean nutrition and stress management as daily inputs. https://www.youtube-nocookie.com/embed/_pYE6u_nMpA 488 2026-08-22T23:00:06.000Z 2026-10-22T22:48:58.955Z https://longevityharbor.com/de/watch/_pYE6u_nMpA Videobeschreibung: Sinclairs epigenetische Verjüngungsaussagen erklärt https://i.ytimg.com/vi/_pYE6u_nMpA/hqdefault.jpg Die Beschreibung stellt David Sinclairs Ideen zur epigenetischen Verjüngung vor: Methylgruppen-Markierungen driften mit dem Alter, Uhren wie GrimAge und DunedinPACE messen das biologische Alter, und Yamanaka-Faktoren reprogrammieren Zellen teilweise. Zudem nennt sie Schlaf, Fasten, mediterrane Ernährung und Stressmanagement als tägliche Eingaben. https://www.youtube-nocookie.com/embed/_pYE6u_nMpA 488 2026-08-22T23:00:06.000Z 2026-10-22T22:48:58.955Z https://longevityharbor.com/en/watch/_qs-k5gWvgM Three Minutes of Squats: What the Video Says Happens in the Body https://i.ytimg.com/vi/_qs-k5gWvgM/hqdefault.jpg A video description says squats load the thigh muscles and can change heartbeat and breathing, and that muscle movement can support lymph transport. It stresses that three minutes of squats are not a proven detox and that lymph nodes have their own function. https://www.youtube-nocookie.com/embed/_qs-k5gWvgM 912 2026-10-19T08:35:58.000Z 2026-10-22T19:50:37.428Z https://longevityharbor.com/de/watch/_qs-k5gWvgM Drei Minuten Kniebeugen: Was laut Video im Körper passiert https://i.ytimg.com/vi/_qs-k5gWvgM/hqdefault.jpg Eine Videobeschreibung erklärt, dass Kniebeugen die Oberschenkelmuskeln beanspruchen, Herzschlag und Atmung verändern können und Muskelbewegung den Lymphtransport unterstützen kann. Betont wird: Drei Minuten Kniebeugen sind keine belegte Entgiftung, und Lymphknoten haben ihre eigene Funktion. https://www.youtube-nocookie.com/embed/_qs-k5gWvgM 912 2026-10-19T08:35:58.000Z 2026-10-22T19:50:37.428Z https://longevityharbor.com/en/watch/_rQXPoHmFnM Epigenetic clocks described: DNA methylation, clock generations and a 2021 trial https://i.ytimg.com/vi/_rQXPoHmFnM/hqdefault.jpg The description says the video explains epigenetic clocks that read DNA methylation, compares three clock generations, cites a 2021 trial reporting -3.23 years in 8 weeks and warns about lab noise. https://www.youtube-nocookie.com/embed/_rQXPoHmFnM 528 2026-09-23T09:51:04.000Z 2026-10-22T21:57:36.700Z https://longevityharbor.com/de/watch/_rQXPoHmFnM Epigenetische Uhren beschrieben: DNA-Methylierung, Uhrengenerationen und eine Studie von 2021 https://i.ytimg.com/vi/_rQXPoHmFnM/hqdefault.jpg Laut Beschreibung erklärt das Video epigenetische Uhren, die DNA-Methylierung messen, vergleicht drei Uhrengenerationen, nennt eine Studie von 2021 mit -3,23 Jahren in 8 Wochen und warnt vor Labormessrauschen. https://www.youtube-nocookie.com/embed/_rQXPoHmFnM 528 2026-09-23T09:51:04.000Z 2026-10-22T21:57:36.700Z https://longevityharbor.com/en/watch/_tJpfuaEDM4 Bringing Geroscience to Clinical Practice | Prof Andrea Maier https://i.ytimg.com/vi/_tJpfuaEDM4/hqdefault.jpg The study of molecular and cellular mechanisms in #ageing has brought about new emphasis on #geroscience-based therapies in humans. Join Prof Brian Kennedy and Prof Andrea Maier in this HealthyLongevity #webinar session as they discuss cutting-edge geroscience research and in particular, how lifestyle interventions, repurposed drugs and novel compounds could lead to better health outcomes. Register for the upcoming webinar​​ sessions here: https://nus-sg.zoom.us/webinar/register/3016397215018/WN__sypkX6ZSomc7cGAkK3LbA #NUSMedicine​​​​​ #webinarseries​​​​​ --- Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material. https://www.youtube-nocookie.com/embed/_tJpfuaEDM4 3717 2021-04-16T01:10:45.000Z 2026-10-22T17:43:40.185Z https://longevityharbor.com/de/watch/_tJpfuaEDM4 Bringing Geroscience to Clinical Practice | Prof Andrea Maier https://i.ytimg.com/vi/_tJpfuaEDM4/hqdefault.jpg The study of molecular and cellular mechanisms in #ageing has brought about new emphasis on #geroscience-based therapies in humans. Join Prof Brian Kennedy and Prof Andrea Maier in this HealthyLongevity #webinar session as they discuss cutting-edge geroscience research and in particular, how lifestyle interventions, repurposed drugs and novel compounds could lead to better health outcomes. Register for the upcoming webinar​​ sessions here: https://nus-sg.zoom.us/webinar/register/3016397215018/WN__sypkX6ZSomc7cGAkK3LbA #NUSMedicine​​​​​ #webinarseries​​​​​ --- Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material. https://www.youtube-nocookie.com/embed/_tJpfuaEDM4 3717 2021-04-16T01:10:45.000Z 2026-10-22T17:43:40.185Z https://longevityharbor.com/en/watch/_uGyCIoDLTo A4LI Scientist Spotlight - Dr. Gabriel Guerrero https://i.ytimg.com/vi/_uGyCIoDLTo/hqdefault.jpg The Alliance for Longevity Initiatives is proud to announce the launch of our newest podcast, A4LI’s Scientist Spotlight Series. In this series, hosted by Brenda Eap, we invite geroscientists who are actively trying to understand the biology of aging and designing potential geroscience therapeutics that help us live longer, healthier lives. This week, we are joined by Dr. Gabriel Guerrero of BioAge Labs, where we discuss his work as well as how he first became interested in the field of aging research. Please enjoy! https://www.youtube-nocookie.com/embed/_uGyCIoDLTo 968 2023-11-13T21:35:24.000Z 2026-10-22T19:04:38.741Z https://longevityharbor.com/de/watch/_uGyCIoDLTo A4LI Scientist Spotlight - Dr. Gabriel Guerrero https://i.ytimg.com/vi/_uGyCIoDLTo/hqdefault.jpg The Alliance for Longevity Initiatives is proud to announce the launch of our newest podcast, A4LI’s Scientist Spotlight Series. In this series, hosted by Brenda Eap, we invite geroscientists who are actively trying to understand the biology of aging and designing potential geroscience therapeutics that help us live longer, healthier lives. This week, we are joined by Dr. Gabriel Guerrero of BioAge Labs, where we discuss his work as well as how he first became interested in the field of aging research. Please enjoy! https://www.youtube-nocookie.com/embed/_uGyCIoDLTo 968 2023-11-13T21:35:24.000Z 2026-10-22T19:04:38.741Z https://longevityharbor.com/en/watch/_uNFHl-XmzQ Optimizing mTOR for Longevity: Secrets to Health and Lifespan | GlobalRPh https://i.ytimg.com/vi/_uNFHl-XmzQ/hqdefault.jpg Optimizing mTOR for Longevity: Secrets to Health and Lifespan | GlobalRPh The mTOR pathway plays a central role in aging, metabolism, and regenerative biology—but should we always suppress it to promote longevity? Or can strategic, periodic activation through targeted nutrition and exercise provide additional benefits? In this lecture, we explore the latest research on mTOR signaling, examining the balance between chronic suppression and periodic activation, and how this impacts healthspan, muscle preservation, immune function, and even cancer risk. What you'll learn: The fundamentals of mTORC1: nutrient sensing, autophagy, and aging Evidence for chronic mTOR suppression, including caloric restriction and rapamycin Risks of over-suppression, such as sarcopenia and compromised immunity The benefits of periodic nutrient-driven activation using protein pulses and refeeding strategies Practical, evidence-based guidance for healthcare professionals on diet, exercise, and personalized longevity interventions Whether you are a physician, pharmacist, dietitian, or researcher, this lecture provides a nuanced understanding of how to modulate mTOR for optimal aging, functional health, and long-term well-being. 🔔 Subscribe to GlobalRPh for more expert insights on metabolism, clinical nutrition, and longevity science. #LongevityMedicine #mTOR #IntermittentFasting #ProteinTiming #Leucine #NutritionalScience #Pharmacology #HealthyAging #ClinicalNutrition #Healthspan #FunctionalHealth #MetabolicHealth https://www.youtube-nocookie.com/embed/_uNFHl-XmzQ 293 2025-07-08T19:05:00.000Z 2026-10-22T18:43:08.053Z https://longevityharbor.com/de/watch/_uNFHl-XmzQ Optimizing mTOR for Longevity: Secrets to Health and Lifespan | GlobalRPh https://i.ytimg.com/vi/_uNFHl-XmzQ/hqdefault.jpg Optimizing mTOR for Longevity: Secrets to Health and Lifespan | GlobalRPh The mTOR pathway plays a central role in aging, metabolism, and regenerative biology—but should we always suppress it to promote longevity? Or can strategic, periodic activation through targeted nutrition and exercise provide additional benefits? In this lecture, we explore the latest research on mTOR signaling, examining the balance between chronic suppression and periodic activation, and how this impacts healthspan, muscle preservation, immune function, and even cancer risk. What you'll learn: The fundamentals of mTORC1: nutrient sensing, autophagy, and aging Evidence for chronic mTOR suppression, including caloric restriction and rapamycin Risks of over-suppression, such as sarcopenia and compromised immunity The benefits of periodic nutrient-driven activation using protein pulses and refeeding strategies Practical, evidence-based guidance for healthcare professionals on diet, exercise, and personalized longevity interventions Whether you are a physician, pharmacist, dietitian, or researcher, this lecture provides a nuanced understanding of how to modulate mTOR for optimal aging, functional health, and long-term well-being. 🔔 Subscribe to GlobalRPh for more expert insights on metabolism, clinical nutrition, and longevity science. #LongevityMedicine #mTOR #IntermittentFasting #ProteinTiming #Leucine #NutritionalScience #Pharmacology #HealthyAging #ClinicalNutrition #Healthspan #FunctionalHealth #MetabolicHealth https://www.youtube-nocookie.com/embed/_uNFHl-XmzQ 293 2025-07-08T19:05:00.000Z 2026-10-22T18:43:08.053Z https://longevityharbor.com/en/watch/_vUBnhW8FsI Nutricost NMN Review (2025) — Real Anti-Aging Support or Just Hype? https://i.ytimg.com/vi/_vUBnhW8FsI/hqdefault.jpg Is Nutricost NMN the real deal? 🤔 This video reviews a budget-friendly **nmn supplement** and its impact on **nad supplement** levels and potential **anti aging** effects. We'll discuss **nmn benefits** and if these **supplements** help boost **nad benefits**. For educational purposes only. Not a doctor's recommendation. Nutricost NMN Review (2025) — does this supplement truly support anti-aging, energy, and longevity, or is it just hype? We analyze ingredients, dosage, and real user results. Find out if Nutricost NMN is worth the money in 2025 or if better NAD+ boosters exist. https://www.youtube-nocookie.com/embed/_vUBnhW8FsI 266 2025-10-22T04:45:46.000Z 2026-10-22T17:43:42.547Z https://longevityharbor.com/de/watch/_vUBnhW8FsI Nutricost NMN Review (2025) — Real Anti-Aging Support or Just Hype? https://i.ytimg.com/vi/_vUBnhW8FsI/hqdefault.jpg Is Nutricost NMN the real deal? 🤔 This video reviews a budget-friendly **nmn supplement** and its impact on **nad supplement** levels and potential **anti aging** effects. We'll discuss **nmn benefits** and if these **supplements** help boost **nad benefits**. For educational purposes only. Not a doctor's recommendation. Nutricost NMN Review (2025) — does this supplement truly support anti-aging, energy, and longevity, or is it just hype? We analyze ingredients, dosage, and real user results. Find out if Nutricost NMN is worth the money in 2025 or if better NAD+ boosters exist. https://www.youtube-nocookie.com/embed/_vUBnhW8FsI 266 2025-10-22T04:45:46.000Z 2026-10-22T17:43:42.547Z https://longevityharbor.com/en/watch/_wy3AAdY9iE Chair squats for people over 60: a video description's claims https://i.ytimg.com/vi/_wy3AAdY9iE/hqdefault.jpg The description presents chair squats as a safe, equipment-free exercise for people over 60 and claims benefits for strength, falls and independence. These are creator claims; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/_wy3AAdY9iE 369 2026-06-13T16:00:18.000Z 2026-10-22T23:59:25.768Z https://longevityharbor.com/de/watch/_wy3AAdY9iE Stuhl-Kniebeugen für Menschen über 60: Aussagen einer Videobeschreibung https://i.ytimg.com/vi/_wy3AAdY9iE/hqdefault.jpg Die Beschreibung stellt Stuhl-Kniebeugen als sichere, gerätefreie Übung für Menschen über 60 vor und nennt Vorteile für Kraft, Stürze und Selbstständigkeit. Das sind Aussagen des Erstellers; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/_wy3AAdY9iE 369 2026-06-13T16:00:18.000Z 2026-10-22T23:59:25.768Z https://longevityharbor.com/en/watch/_x47SWsPsCo HIV-1 Infection Accelerates Age According to the Epigenetic Clock | Steve Horvath, PhD https://i.ytimg.com/vi/_x47SWsPsCo/hqdefault.jpg Lecture: HIV-1 Infection Accelerates Age According to the Epigenetic Clock Speaker: Steve Horvath, PhD UCLA, United States of America Presented at: International Workshop on HIV & Aging 2016 Learn more about International Workshop on HIV & Aging 2021 that will take place from 23 September 2021 to 24 September 2021 via https://bit.ly/3tiGoJa The integration of antiretroviral therapy (ART) into HIV care has dramatically extended the life expectancy of those living with HIV. The longer life expectancy of people with HIV infection is changing the demographics of the HIV epidemic and currently, more than half of the people living with HIV are aged 45 or older. Recent estimates in Europe suggest that more than 70% of those with HIV will be over the age of 50 by 2030, with a greater burden of co-morbidities and associated treatments. In comparison to similar HIV-negative populations, HIV-positive persons, even when on effective ART, experience an excess of morbidity and mortality. Persons on ART rarely die from complications of AIDS, but instead have an early onset of aging complications including neurocognitive decline, osteoporosis and fractures, impaired physical function, frailty, and falls. The high priority of understanding the interaction between age and HIV infection is illustrated by recent summary reports from the HIV and Aging Consensus Project in the Journal of the American Geriatrics Society and ongoing NIH Program Announcements in “Multidisciplinary Studies of HIV/AIDS and Aging”, in addition to strong voices in the community. Registration for the webinar is open and fee is waived for healthcare professionals via this link https://bit.ly/2R1c2Of For the Enduring Materials of the 2016 edition visit https://bit.ly/3ttl6Zb For more medical education programs, as well as the latest scientific information, visit https://academicmedicaleducation.com/ https://www.youtube-nocookie.com/embed/_x47SWsPsCo 1894 2021-03-31T11:13:42.000Z 2026-10-22T17:43:35.290Z https://longevityharbor.com/de/watch/_x47SWsPsCo HIV-1 Infection Accelerates Age According to the Epigenetic Clock | Steve Horvath, PhD https://i.ytimg.com/vi/_x47SWsPsCo/hqdefault.jpg Lecture: HIV-1 Infection Accelerates Age According to the Epigenetic Clock Speaker: Steve Horvath, PhD UCLA, United States of America Presented at: International Workshop on HIV & Aging 2016 Learn more about International Workshop on HIV & Aging 2021 that will take place from 23 September 2021 to 24 September 2021 via https://bit.ly/3tiGoJa The integration of antiretroviral therapy (ART) into HIV care has dramatically extended the life expectancy of those living with HIV. The longer life expectancy of people with HIV infection is changing the demographics of the HIV epidemic and currently, more than half of the people living with HIV are aged 45 or older. Recent estimates in Europe suggest that more than 70% of those with HIV will be over the age of 50 by 2030, with a greater burden of co-morbidities and associated treatments. In comparison to similar HIV-negative populations, HIV-positive persons, even when on effective ART, experience an excess of morbidity and mortality. Persons on ART rarely die from complications of AIDS, but instead have an early onset of aging complications including neurocognitive decline, osteoporosis and fractures, impaired physical function, frailty, and falls. The high priority of understanding the interaction between age and HIV infection is illustrated by recent summary reports from the HIV and Aging Consensus Project in the Journal of the American Geriatrics Society and ongoing NIH Program Announcements in “Multidisciplinary Studies of HIV/AIDS and Aging”, in addition to strong voices in the community. Registration for the webinar is open and fee is waived for healthcare professionals via this link https://bit.ly/2R1c2Of For the Enduring Materials of the 2016 edition visit https://bit.ly/3ttl6Zb For more medical education programs, as well as the latest scientific information, visit https://academicmedicaleducation.com/ https://www.youtube-nocookie.com/embed/_x47SWsPsCo 1894 2021-03-31T11:13:42.000Z 2026-10-22T17:43:35.290Z https://longevityharbor.com/en/watch/_y4LP1C9j6U The Longevity Discovery Hidden in Dolphins https://i.ytimg.com/vi/_y4LP1C9j6U/hqdefault.jpg Hosts: Phil Newman: https://qrco.de/bgXpNY Nina Patrick: ⁠⁠https://qrco.de/bgXpKn ---------- Sponsor: Fatty15 Fatty15 is a science-backed, patented, award-winning supplement with pure C15:0 that strengthens cell membranes and supports healthy aging at the cellular level. Benefits include deeper sleep, calmer mood, improved energy, and overall wellbeing. Click the link below to learn more and use code UNLOCKED for 15% off the 90-day Starter Kit. Link: https://fatty15.com/UNLOCKED ---------- Guests: Stephanie Venn-Watson, DVM, MPH Co-Founder, Chief Executive Officer, Fatty15 LinkedIn: https://www.linkedin.com/in/stephanievennwatson/ Website: https://fatty15.com/ Nicholas J. Schork, PhD, MA Co-Founder, Senior Sciencist, Fatty15 Research: https://www.researchgate.net/profile/Nicholas-Schork Website: https://fatty15.com/ ---------- What if one of the most influential nutrition recommendations of the last 50 years overlooked a nutrient essential for long-term health? Phil Newman and Dr. Nina Patrick sit down with Dr. Stephanie Venn-Watson, veterinary epidemiologist, public health scientist, inventor, and co-founder of Fatty15, alongside Dr. Nicholas Schork, distinguished professor and leading researcher in quantitative medicine and longevity science, to explore the emerging evidence behind C15 and the future of nutrition research. Together they examine how dietary guidelines introduced in 1977 led to widespread reductions in saturated fat consumption, while rates of obesity, metabolic disease, fatty liver disease, and type 2 diabetes continued to climb. Drawing on evidence from population studies, molecular biology, and animal research, they discuss why not all saturated fats behave the same way and how advances in metabolomics are helping researchers identify specific nutrients that may play critical roles in health and aging. The conversation traces the remarkable discovery of C15 from aging Navy dolphins, where researchers found that higher C15 levels were associated with healthier aging and lower rates https://www.youtube-nocookie.com/embed/_y4LP1C9j6U 3033 2026-06-29T07:49:20.000Z 2026-10-22T19:32:33.479Z https://longevityharbor.com/de/watch/_y4LP1C9j6U The Longevity Discovery Hidden in Dolphins https://i.ytimg.com/vi/_y4LP1C9j6U/hqdefault.jpg Hosts: Phil Newman: https://qrco.de/bgXpNY Nina Patrick: ⁠⁠https://qrco.de/bgXpKn ---------- Sponsor: Fatty15 Fatty15 is a science-backed, patented, award-winning supplement with pure C15:0 that strengthens cell membranes and supports healthy aging at the cellular level. Benefits include deeper sleep, calmer mood, improved energy, and overall wellbeing. Click the link below to learn more and use code UNLOCKED for 15% off the 90-day Starter Kit. Link: https://fatty15.com/UNLOCKED ---------- Guests: Stephanie Venn-Watson, DVM, MPH Co-Founder, Chief Executive Officer, Fatty15 LinkedIn: https://www.linkedin.com/in/stephanievennwatson/ Website: https://fatty15.com/ Nicholas J. Schork, PhD, MA Co-Founder, Senior Sciencist, Fatty15 Research: https://www.researchgate.net/profile/Nicholas-Schork Website: https://fatty15.com/ ---------- What if one of the most influential nutrition recommendations of the last 50 years overlooked a nutrient essential for long-term health? Phil Newman and Dr. Nina Patrick sit down with Dr. Stephanie Venn-Watson, veterinary epidemiologist, public health scientist, inventor, and co-founder of Fatty15, alongside Dr. Nicholas Schork, distinguished professor and leading researcher in quantitative medicine and longevity science, to explore the emerging evidence behind C15 and the future of nutrition research. Together they examine how dietary guidelines introduced in 1977 led to widespread reductions in saturated fat consumption, while rates of obesity, metabolic disease, fatty liver disease, and type 2 diabetes continued to climb. Drawing on evidence from population studies, molecular biology, and animal research, they discuss why not all saturated fats behave the same way and how advances in metabolomics are helping researchers identify specific nutrients that may play critical roles in health and aging. The conversation traces the remarkable discovery of C15 from aging Navy dolphins, where researchers found that higher C15 levels were associated with healthier aging and lower rates https://www.youtube-nocookie.com/embed/_y4LP1C9j6U 3033 2026-06-29T07:49:20.000Z 2026-10-22T19:32:33.479Z https://longevityharbor.com/en/watch/a-CpKYfsT-o Video description proposes a "stacked approach" combining longevity interventions https://i.ytimg.com/vi/a-CpKYfsT-o/hqdefault.jpg The description presents stacking—combining pharmaceuticals, nutraceuticals and lifestyle changes—as a proposed strategy to target several hallmarks of aging at once. It cites early research, including Interventions Testing Program data, as suggesting possible synergistic healthspan benefits, but gives no study details. https://www.youtube-nocookie.com/embed/a-CpKYfsT-o 94 2026-01-12T11:51:47.000Z 2026-10-23T02:54:46.347Z https://longevityharbor.com/de/watch/a-CpKYfsT-o Videobeschreibung schlägt einen "Stacked Approach" aus kombinierten Longevity-Interventionen vor https://i.ytimg.com/vi/a-CpKYfsT-o/hqdefault.jpg Die Beschreibung stellt Stacking – die Kombination von Arzneimitteln, Nahrungsergänzungsmitteln und Lebensstiländerungen – als vorgeschlagene Strategie vor, um mehrere Hallmarks des Alterns zugleich anzugehen. Sie nennt frühe Forschung, darunter Daten des Interventions Testing Program, als Hinweis auf mögliche synergistische Healthspan-Vorteile, ohne Studiendetails zu nennen. https://www.youtube-nocookie.com/embed/a-CpKYfsT-o 94 2026-01-12T11:51:47.000Z 2026-10-23T02:54:46.347Z https://longevityharbor.com/en/watch/a1TC4v_OTq4 Podcast description: cellular aging, 12 hallmarks and metabolic health https://i.ytimg.com/vi/a1TC4v_OTq4/hqdefault.jpg In this podcast description, Dr. Young presents aging as cellular maintenance and repair, describes a framework of 12 hallmarks of aging, and links metabolic health, inflammation and cardiorespiratory fitness to longevity. The description is promotional; video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/a1TC4v_OTq4 3321 2026-03-25T20:28:05.000Z 2026-10-23T01:52:01.449Z https://longevityharbor.com/de/watch/a1TC4v_OTq4 Podcast-Beschreibung: Zellalterung, 12 Hallmarks und Stoffwechselgesundheit https://i.ytimg.com/vi/a1TC4v_OTq4/hqdefault.jpg In dieser Podcast-Beschreibung stellt Dr. Young Altern als zelluläre Instandhaltung und Reparatur dar, beschreibt einen Rahmen von 12 Hallmarks des Alterns und verknüpft Stoffwechselgesundheit, Entzündung und kardiorespiratorische Fitness mit Langlebigkeit. Die Beschreibung ist werblich; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/a1TC4v_OTq4 3321 2026-03-25T20:28:05.000Z 2026-10-23T01:52:01.449Z https://longevityharbor.com/en/watch/a2x6UajgF6c The Science of Aging: Unveiling the Secrets of Cellular Senescence https://i.ytimg.com/vi/a2x6UajgF6c/hqdefault.jpg Delve into the fascinating world of cellular senescence, a key player in the science of aging. In this video, we explore how cells age, the double-edged sword of senescence (tumor suppression vs. age-related diseases), and the latest research on senolytics and senomorphics as potential anti-aging therapies. Discover how healthy lifestyle choices can impact cellular senescence and your overall healthspan. cellular senescence aging science of aging age-related diseases tumor suppression SASP inflammaging senolytics senomorphics anti-aging therapies lifespan healthspan longevity DNA damage oxidative stress telomeres wound healing tissue regeneration chronic inflammation healthy aging lifestyle choices aging process how we age aging research aging science cellular biology cell biology cell aging aging gracefully healthy lifestyle longevity secrets anti-aging secrets https://www.youtube-nocookie.com/embed/a2x6UajgF6c 381 2024-07-02T08:54:53.000Z 2026-10-22T19:21:23.352Z https://longevityharbor.com/de/watch/a2x6UajgF6c The Science of Aging: Unveiling the Secrets of Cellular Senescence https://i.ytimg.com/vi/a2x6UajgF6c/hqdefault.jpg Delve into the fascinating world of cellular senescence, a key player in the science of aging. In this video, we explore how cells age, the double-edged sword of senescence (tumor suppression vs. age-related diseases), and the latest research on senolytics and senomorphics as potential anti-aging therapies. Discover how healthy lifestyle choices can impact cellular senescence and your overall healthspan. cellular senescence aging science of aging age-related diseases tumor suppression SASP inflammaging senolytics senomorphics anti-aging therapies lifespan healthspan longevity DNA damage oxidative stress telomeres wound healing tissue regeneration chronic inflammation healthy aging lifestyle choices aging process how we age aging research aging science cellular biology cell biology cell aging aging gracefully healthy lifestyle longevity secrets anti-aging secrets https://www.youtube-nocookie.com/embed/a2x6UajgF6c 381 2024-07-02T08:54:53.000Z 2026-10-22T19:21:23.352Z https://longevityharbor.com/en/watch/a4uuEHDCbco Niagen scientist describes NR vs NMN and label-testing claims https://i.ytimg.com/vi/a4uuEHDCbco/hqdefault.jpg In this video description, a Niagen Bioscience scientist says NR enters cells directly while NMN must be broken down first, and that testing found most NAD products missed label claims. https://www.youtube-nocookie.com/embed/a4uuEHDCbco 1206 2026-05-17T15:11:44.000Z 2026-10-23T00:45:14.485Z https://longevityharbor.com/de/watch/a4uuEHDCbco Niagen-Wissenschaftler beschreibt NR vs. NMN und Etikett-Testaussagen https://i.ytimg.com/vi/a4uuEHDCbco/hqdefault.jpg In dieser Videobeschreibung sagt ein Wissenschaftler von Niagen Bioscience, NR gelange direkt in Zellen, während NMN erst abgebaut werden müsse, und Tests hätten ergeben, dass die meisten NAD-Produkte die Etikettangaben verfehlten. https://www.youtube-nocookie.com/embed/a4uuEHDCbco 1206 2026-05-17T15:11:44.000Z 2026-10-23T00:45:14.485Z https://longevityharbor.com/en/watch/aAvcZx-sCm4 Why Fasting May Affect Cellular Aging Differently Than Exercise | Science Explained https://i.ytimg.com/vi/aAvcZx-sCm4/hqdefault.jpg Why Fasting May Affect Cellular Aging Differently Than Exercise | Science Explained What really happens inside your cells when you go without food for several hours? And how does fasting compare with exercise when it comes to cellular repair, metabolism, and healthy aging? In this video, we explore the fascinating science of autophagy, a natural cellular recycling process that helps your cells break down and reuse certain damaged or unnecessary components. You'll learn how nutrient availability influences pathways such as mTOR and AMPK, why fasting has attracted so much attention from aging researchers, and what scientists have actually discovered in human studies. We'll also compare fasting with exercise and explain why these two strategies affect the body differently. Exercise can improve insulin sensitivity, cardiovascular fitness, muscle strength, and mitochondrial function, while periods without food can alter nutrient-sensing pathways involved in cellular maintenance. In this video, you'll discover: 🧬 What autophagy actually does inside your cells ⏰ Why there is no exact “autophagy starts at 16 hours” rule 🔬 What the Nobel Prize-winning research discovered ⚡ How fasting influences AMPK and mTOR 🏃 How exercise affects cellular pathways 🧠 What fasting research suggests about brain health 🩸 What recent human studies have found ⏳ What scientists really know about fasting and aging ⚠️ Who should be cautious with fasting 💡 Why longer fasting isn't necessarily better Chapters: 00:00 The Cellular Process Most People Ignore 01:30 What Is Autophagy? 04:00 The Nobel Prize Connection 06:30 What Happens When You Stop Eating 09:00 AMPK vs. mTOR Explained 12:00 Fasting vs. Exercise 15:00 What Human Studies Actually Show 18:30 Fasting and Metabolic Health 21:00 What About the Brain? 23:30 Does Fasting Slow Aging? 26:00 Who Should Be Careful? 28:00 The Science-Based Takeaway Important: Fasting is not a proven “cellular reset,” and there is no established fasting duration that guarantees increased autophagy or lo https://www.youtube-nocookie.com/embed/aAvcZx-sCm4 1233 2026-10-03T14:43:14.000Z 2026-10-22T19:54:18.170Z https://longevityharbor.com/de/watch/aAvcZx-sCm4 Why Fasting May Affect Cellular Aging Differently Than Exercise | Science Explained https://i.ytimg.com/vi/aAvcZx-sCm4/hqdefault.jpg Why Fasting May Affect Cellular Aging Differently Than Exercise | Science Explained What really happens inside your cells when you go without food for several hours? And how does fasting compare with exercise when it comes to cellular repair, metabolism, and healthy aging? In this video, we explore the fascinating science of autophagy, a natural cellular recycling process that helps your cells break down and reuse certain damaged or unnecessary components. You'll learn how nutrient availability influences pathways such as mTOR and AMPK, why fasting has attracted so much attention from aging researchers, and what scientists have actually discovered in human studies. We'll also compare fasting with exercise and explain why these two strategies affect the body differently. Exercise can improve insulin sensitivity, cardiovascular fitness, muscle strength, and mitochondrial function, while periods without food can alter nutrient-sensing pathways involved in cellular maintenance. In this video, you'll discover: 🧬 What autophagy actually does inside your cells ⏰ Why there is no exact “autophagy starts at 16 hours” rule 🔬 What the Nobel Prize-winning research discovered ⚡ How fasting influences AMPK and mTOR 🏃 How exercise affects cellular pathways 🧠 What fasting research suggests about brain health 🩸 What recent human studies have found ⏳ What scientists really know about fasting and aging ⚠️ Who should be cautious with fasting 💡 Why longer fasting isn't necessarily better Chapters: 00:00 The Cellular Process Most People Ignore 01:30 What Is Autophagy? 04:00 The Nobel Prize Connection 06:30 What Happens When You Stop Eating 09:00 AMPK vs. mTOR Explained 12:00 Fasting vs. Exercise 15:00 What Human Studies Actually Show 18:30 Fasting and Metabolic Health 21:00 What About the Brain? 23:30 Does Fasting Slow Aging? 26:00 Who Should Be Careful? 28:00 The Science-Based Takeaway Important: Fasting is not a proven “cellular reset,” and there is no established fasting duration that guarantees increased autophagy or lo https://www.youtube-nocookie.com/embed/aAvcZx-sCm4 1233 2026-10-03T14:43:14.000Z 2026-10-22T19:54:18.170Z https://longevityharbor.com/en/watch/aE7oBYC6Vfo The Benefits of Calorie Restriction for Longevity https://i.ytimg.com/vi/aE7oBYC6Vfo/hqdefault.jpg Though a bane for dieters, a slower metabolism may actually be a good thing. New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/ This is part of my video series on calorie restriction, intermittent fasting, and time-restricted eating. Next up is Potential Pitfalls of Calorie Restriction (https://nutritionfacts.org/video/potential-pitfalls-of-calorie-restriction). The rest coming out over the next few months are: • Benefits of Fasting for Weight Loss Put to the Test (https://nutritionfacts.org/video/benefits-of-fasting-for-weight-loss-put-to-the-test) • Is Fasting Beneficial for Weight Loss? (https://nutritionfacts.org/video/is-fasting-beneficial-for-weight-loss) • Is Fasting for Weight Loss Safe? (https://nutritionfacts.org/video/is-fasting-for-weight-loss-safe) • Alternate-Day Intermittent Fasting Put to the Test (https://nutritionfacts.org/video/Alternate-Day-Intermittent-Fasting-Put-to-the-Test) • Is Alternate-Day Intermittent Fasting Safe? (https://nutritionfacts.org/video/is-alternate-day-intermittent-fasting-safe) • Does Intermittent Fasting Increase Human Life Expectancy? (https://nutritionfacts.org/video/does-intermittent-fasting-increase-human-life-expectancy) • The 5:2 Diet and the Fasting-Mimicking Diet Put to the Test (https://nutritionfacts.org/video/the-5-2-diet-and-the-fasting-mimicking-diet-put-to-the-test) • Time-Restricted Eating Put to the Test (https://nutritionfacts.org/video/time-restricted-eating-put-to-the-test) • The Benefits of Early Time-Restricted Eating (https://nutritionfacts.org/video/the-benefits-of-early-time-restricted-eating) If you don’t want to wait you can watch them all now on a digital download (https://drgreger.org/collections/downloads/products/fasting-weight-loss-digital). If you’re watching this the day it comes out, there are two days left to register for my 3rd and final fasting webinar, Fasting and Cancer, here (https://nutritionfacts.org/webinar/fasting-cancer/). Have a question about this https://www.youtube-nocookie.com/embed/aE7oBYC6Vfo 321 2019-10-16T11:59:48.000Z 2026-10-22T17:43:38.414Z https://longevityharbor.com/de/watch/aE7oBYC6Vfo The Benefits of Calorie Restriction for Longevity https://i.ytimg.com/vi/aE7oBYC6Vfo/hqdefault.jpg Though a bane for dieters, a slower metabolism may actually be a good thing. New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/ This is part of my video series on calorie restriction, intermittent fasting, and time-restricted eating. Next up is Potential Pitfalls of Calorie Restriction (https://nutritionfacts.org/video/potential-pitfalls-of-calorie-restriction). The rest coming out over the next few months are: • Benefits of Fasting for Weight Loss Put to the Test (https://nutritionfacts.org/video/benefits-of-fasting-for-weight-loss-put-to-the-test) • Is Fasting Beneficial for Weight Loss? (https://nutritionfacts.org/video/is-fasting-beneficial-for-weight-loss) • Is Fasting for Weight Loss Safe? (https://nutritionfacts.org/video/is-fasting-for-weight-loss-safe) • Alternate-Day Intermittent Fasting Put to the Test (https://nutritionfacts.org/video/Alternate-Day-Intermittent-Fasting-Put-to-the-Test) • Is Alternate-Day Intermittent Fasting Safe? (https://nutritionfacts.org/video/is-alternate-day-intermittent-fasting-safe) • Does Intermittent Fasting Increase Human Life Expectancy? (https://nutritionfacts.org/video/does-intermittent-fasting-increase-human-life-expectancy) • The 5:2 Diet and the Fasting-Mimicking Diet Put to the Test (https://nutritionfacts.org/video/the-5-2-diet-and-the-fasting-mimicking-diet-put-to-the-test) • Time-Restricted Eating Put to the Test (https://nutritionfacts.org/video/time-restricted-eating-put-to-the-test) • The Benefits of Early Time-Restricted Eating (https://nutritionfacts.org/video/the-benefits-of-early-time-restricted-eating) If you don’t want to wait you can watch them all now on a digital download (https://drgreger.org/collections/downloads/products/fasting-weight-loss-digital). If you’re watching this the day it comes out, there are two days left to register for my 3rd and final fasting webinar, Fasting and Cancer, here (https://nutritionfacts.org/webinar/fasting-cancer/). Have a question about this https://www.youtube-nocookie.com/embed/aE7oBYC6Vfo 321 2019-10-16T11:59:48.000Z 2026-10-22T17:43:38.414Z https://longevityharbor.com/en/watch/aFFjwyLNitY Senescent cells and fisetin: what the video description covers https://i.ytimg.com/vi/aFFjwyLNitY/hqdefault.jpg The description says researchers are investigating whether senescent cells and the signals they release influence aging, and why fisetin is being studied as a possible senolytic. It stresses separating laboratory and animal research from proven human benefits. https://www.youtube-nocookie.com/embed/aFFjwyLNitY 130 2026-08-22T16:05:35.000Z 2026-10-22T22:49:17.387Z https://longevityharbor.com/de/watch/aFFjwyLNitY Seneszente Zellen und Fisetin: was die Videobeschreibung abdeckt https://i.ytimg.com/vi/aFFjwyLNitY/hqdefault.jpg Laut Beschreibung untersuchen Forschende, ob seneszente Zellen und ihre Signale das Altern beeinflussen, und warum Fisetin als mögliches Senolytikum erforscht wird. Sie betont, Labor- und Tierforschung von belegtem Nutzen beim Menschen zu trennen. https://www.youtube-nocookie.com/embed/aFFjwyLNitY 130 2026-08-22T16:05:35.000Z 2026-10-22T22:49:17.387Z https://longevityharbor.com/en/watch/aHeWKkJy_Eo What Science Really Says About Diet, Healthy Aging, and Longevity https://i.ytimg.com/vi/aHeWKkJy_Eo/hqdefault.jpg What if everything you’ve been told about aging and nutrition is wrong—and it’s not too late to change your future? Dr. Federica Amati shares surprising and powerful nutrition insights about nutrition and aging, and busts a lot of myths along the way. ========== Listen to full line-up of 8-10 episodes/month + 1,000 plus episode archive: A few times a month, we air select episodes of the Good Life Project® podcast here on Youtube. Access the full roster of 8-10 new episodes a month, and a giant library of over 1,000 past episodes, featuring luminaries from science, health, art, entertainment, spirituality, and business here: : https://episodes.fm/647826736 ========== Want to live a better life? Take the FREE Good Life Bucket Quiz: https://www.goodlifeproject.com/good-life-buckets/ ========== Timestamps: 00:00 Food Culture: How It’s Evolving 00:26 Dr. Federica Amani: Nutrition Scientist 00:49 Early Diet & Brain Health 01:01 What Drives Amani’s Research 01:54 Nutrition at Every Age 04:10 Is It Too Late to Eat Better? 05:01 Diet, Aging & Longevity 20:26 Midlife Nutrition Matters 23:56 Protein Needs After 40 38:15 Appetite Changes With Age 39:03 Protein, Exercise & Muscle Loss 40:06 Nitrogen Balance Explained 42:25 Consistency: Diet & Fitness 47:48 Diet & Bone Density 50:25 Gut Health & Bone Strength 55:22 Nutrition & Cognitive Decline 01:08:10 Evolution & Modern Eating 01:13:51 Future of Public Health Nutrition ========== Follow Good Life Project®: Instagram - https://www.instagram.com/goodlifeproject/ Website - https://www.goodlifeproject.com/ Follow Jonathan Fields: Instagram:https://www.instagram.com/jonathanfields/ LinkedIn: https://www.linkedin.com/in/jonathanfields1/ Website: https://www.jonathanfields.com/ Subscribe to Jonathan's free newsletter: https://jonathanfields.substack.com/ ========== Follow Dr. Federica Amati: Instagram - https://www.instagram.com/dr.fede.amati/?hl=en Website - https://fedeamati.substack.com/ Get Federica Amati's book, Every Body Should Know This: The Science of Eating https://www.youtube-nocookie.com/embed/aHeWKkJy_Eo 4758 2025-05-15T13:00:02.000Z 2026-10-22T18:43:11.786Z https://longevityharbor.com/de/watch/aHeWKkJy_Eo What Science Really Says About Diet, Healthy Aging, and Longevity https://i.ytimg.com/vi/aHeWKkJy_Eo/hqdefault.jpg What if everything you’ve been told about aging and nutrition is wrong—and it’s not too late to change your future? Dr. Federica Amati shares surprising and powerful nutrition insights about nutrition and aging, and busts a lot of myths along the way. ========== Listen to full line-up of 8-10 episodes/month + 1,000 plus episode archive: A few times a month, we air select episodes of the Good Life Project® podcast here on Youtube. Access the full roster of 8-10 new episodes a month, and a giant library of over 1,000 past episodes, featuring luminaries from science, health, art, entertainment, spirituality, and business here: : https://episodes.fm/647826736 ========== Want to live a better life? Take the FREE Good Life Bucket Quiz: https://www.goodlifeproject.com/good-life-buckets/ ========== Timestamps: 00:00 Food Culture: How It’s Evolving 00:26 Dr. Federica Amani: Nutrition Scientist 00:49 Early Diet & Brain Health 01:01 What Drives Amani’s Research 01:54 Nutrition at Every Age 04:10 Is It Too Late to Eat Better? 05:01 Diet, Aging & Longevity 20:26 Midlife Nutrition Matters 23:56 Protein Needs After 40 38:15 Appetite Changes With Age 39:03 Protein, Exercise & Muscle Loss 40:06 Nitrogen Balance Explained 42:25 Consistency: Diet & Fitness 47:48 Diet & Bone Density 50:25 Gut Health & Bone Strength 55:22 Nutrition & Cognitive Decline 01:08:10 Evolution & Modern Eating 01:13:51 Future of Public Health Nutrition ========== Follow Good Life Project®: Instagram - https://www.instagram.com/goodlifeproject/ Website - https://www.goodlifeproject.com/ Follow Jonathan Fields: Instagram:https://www.instagram.com/jonathanfields/ LinkedIn: https://www.linkedin.com/in/jonathanfields1/ Website: https://www.jonathanfields.com/ Subscribe to Jonathan's free newsletter: https://jonathanfields.substack.com/ ========== Follow Dr. Federica Amati: Instagram - https://www.instagram.com/dr.fede.amati/?hl=en Website - https://fedeamati.substack.com/ Get Federica Amati's book, Every Body Should Know This: The Science of Eating https://www.youtube-nocookie.com/embed/aHeWKkJy_Eo 4758 2025-05-15T13:00:02.000Z 2026-10-22T18:43:11.786Z https://longevityharbor.com/en/watch/aK2oulrWSBM Video description lists 20 Japanese foods claimed to support longevity https://i.ytimg.com/vi/aK2oulrWSBM/hqdefault.jpg The description presents 20 traditional Japanese foods, from matcha and natto to purple sweet potato and Hokkaido salmon, as linked to Okinawan centenarian diets and to mechanisms of aging; it attributes these claims to the video and cites no studies. https://www.youtube-nocookie.com/embed/aK2oulrWSBM 2742 2026-03-14T16:00:01.000Z 2026-10-23T02:09:24.241Z https://longevityharbor.com/de/watch/aK2oulrWSBM Videobeschreibung nennt 20 japanische Lebensmittel mit behaupteter Langlebigkeitswirkung https://i.ytimg.com/vi/aK2oulrWSBM/hqdefault.jpg Die Beschreibung stellt 20 traditionelle japanische Lebensmittel – von Matcha und Natto bis Süßkartoffel und Hokkaido-Lachs – als mit der Ernährung von Hundertjährigen in Okinawa und mit Alternsmechanismen verbunden dar; sie schreibt diese Aussagen dem Video zu und nennt keine Studien. https://www.youtube-nocookie.com/embed/aK2oulrWSBM 2742 2026-03-14T16:00:01.000Z 2026-10-23T02:09:24.241Z https://longevityharbor.com/en/watch/aKgmB_n3uO4 How Sleep Quality Changes After 60 — And What Science Says to Fix It https://i.ytimg.com/vi/aKgmB_n3uO4/hqdefault.jpg UNITED STATES Struggling with poor sleep after 60? You're not alone — and it's not just "part of aging." Science now shows that changes in hormone levels, brain chemistry, and daily routines significantly disrupt deep sleep, making you more vulnerable to fatigue, memory loss, weakened immunity, and even heart problems. In this video, EverYoungMind explores how aging affects sleep architecture — and what neuroscience, circadian biology, and clinical research suggest you can do to restore healthy rest. From natural melatonin rhythms to proven lifestyle interventions, you’ll learn exactly how to upgrade your sleep and protect your mind and body as you age. If you’re tired of waking up tired, this is where science meets solutions. Subscribe for weekly insights that help you live longer, think clearer, and feel better — at any age. sleep after 60,aging and insomnia,science of sleep,sleep quality decline,sleep tips for seniors,neuroscience of sleep,melatonin and aging,deep sleep restoration,ever young mind,restorative sleep science #SleepHealth #Over60 #EverYoungMind #Neuroscience #SleepScience #HealthyAging #RestfulSleep #BetterSleep #CircadianRhythm #USA #LongevityTips #Melatonin #ScienceBasedHealth https://www.youtube-nocookie.com/embed/aKgmB_n3uO4 840 2025-05-28T17:00:01.000Z 2026-10-22T19:43:49.809Z https://longevityharbor.com/de/watch/aKgmB_n3uO4 How Sleep Quality Changes After 60 — And What Science Says to Fix It https://i.ytimg.com/vi/aKgmB_n3uO4/hqdefault.jpg UNITED STATES Struggling with poor sleep after 60? You're not alone — and it's not just "part of aging." Science now shows that changes in hormone levels, brain chemistry, and daily routines significantly disrupt deep sleep, making you more vulnerable to fatigue, memory loss, weakened immunity, and even heart problems. In this video, EverYoungMind explores how aging affects sleep architecture — and what neuroscience, circadian biology, and clinical research suggest you can do to restore healthy rest. From natural melatonin rhythms to proven lifestyle interventions, you’ll learn exactly how to upgrade your sleep and protect your mind and body as you age. If you’re tired of waking up tired, this is where science meets solutions. Subscribe for weekly insights that help you live longer, think clearer, and feel better — at any age. sleep after 60,aging and insomnia,science of sleep,sleep quality decline,sleep tips for seniors,neuroscience of sleep,melatonin and aging,deep sleep restoration,ever young mind,restorative sleep science #SleepHealth #Over60 #EverYoungMind #Neuroscience #SleepScience #HealthyAging #RestfulSleep #BetterSleep #CircadianRhythm #USA #LongevityTips #Melatonin #ScienceBasedHealth https://www.youtube-nocookie.com/embed/aKgmB_n3uO4 840 2025-05-28T17:00:01.000Z 2026-10-22T19:43:49.809Z https://longevityharbor.com/en/watch/aMrASMDQNpo Nutrition and health in old age: a video description overview https://i.ytimg.com/vi/aMrASMDQNpo/hqdefault.jpg The description says the episode, with Lisa-Marie Brandt, looks at nutrition's role for quality of life, independence and prevention in old age, and promises knowledge plus practical everyday ideas. https://www.youtube-nocookie.com/embed/aMrASMDQNpo 1837 2026-04-16T10:30:02.000Z 2026-10-23T01:34:51.300Z https://longevityharbor.com/de/watch/aMrASMDQNpo Ernährung und Gesundheit im Alter: ein Überblick aus der Videobeschreibung https://i.ytimg.com/vi/aMrASMDQNpo/hqdefault.jpg Laut Beschreibung betrachtet die Folge mit Lisa-Marie Brandt die Rolle der Ernährung für Lebensqualität, Selbstständigkeit und Prävention im Alter und verspricht Wissen sowie praktische Impulse für den Alltag. https://www.youtube-nocookie.com/embed/aMrASMDQNpo 1837 2026-04-16T10:30:02.000Z 2026-10-23T01:34:51.300Z https://longevityharbor.com/en/watch/aNlDZeKLMTo Nmn is the bee’s knees Cata-Kor USA #nmn #nad #ad #antiaging #supplementsthatwork https://i.ytimg.com/vi/aNlDZeKLMTo/hqdefault.jpg Nmn is the bee’s knees Cata-Kor USA #nmn #nad #ad #antiaging #supplementsthatwork https://www.youtube-nocookie.com/embed/aNlDZeKLMTo 119 2026-09-29T03:09:04.000Z 2026-10-22T20:11:47.066Z https://longevityharbor.com/de/watch/aNlDZeKLMTo Nmn is the bee’s knees Cata-Kor USA #nmn #nad #ad #antiaging #supplementsthatwork https://i.ytimg.com/vi/aNlDZeKLMTo/hqdefault.jpg Nmn is the bee’s knees Cata-Kor USA #nmn #nad #ad #antiaging #supplementsthatwork https://www.youtube-nocookie.com/embed/aNlDZeKLMTo 119 2026-09-29T03:09:04.000Z 2026-10-22T20:11:47.066Z https://longevityharbor.com/en/watch/aWYwxAXlEog Video description asks whether NAD or NMN is better for raising NAD⁺ https://i.ytimg.com/vi/aWYwxAXlEog/hqdefault.jpg The description only poses a question: whether NAD or NMN is best for boosting NAD⁺ levels for anti-aging and longevity. It reports no comparison, measurement or result. https://www.youtube-nocookie.com/embed/aWYwxAXlEog 138 2026-08-10T21:11:16.000Z 2026-10-22T23:06:23.296Z https://longevityharbor.com/de/watch/aWYwxAXlEog Videobeschreibung fragt, ob NAD oder NMN NAD⁺ besser erhöht https://i.ytimg.com/vi/aWYwxAXlEog/hqdefault.jpg Die Beschreibung stellt nur eine Frage: ob NAD oder NMN NAD⁺-Spiegel für Anti-Aging und Langlebigkeit am besten steigert. Sie berichtet keinen Vergleich, keine Messung und kein Ergebnis. https://www.youtube-nocookie.com/embed/aWYwxAXlEog 138 2026-08-10T21:11:16.000Z 2026-10-22T23:06:23.296Z https://longevityharbor.com/en/watch/acfHXTaBdgs #59 Alessandro Bitto, PhD: Biological Aging, Cellular Senescence, Mitochondria & the Gut https://i.ytimg.com/vi/acfHXTaBdgs/hqdefault.jpg Dr Alessandro Bitto is a researcher at the University of Washington who studies biological aging, mitochondrial function and metabolic disease. He walks us through the history, current thinking and some of the experimental data of cellular senescence, including the role of DNA damage and telomeres, some of the senolytic drugs (quercetin, Dasatinib and others), and how different cells effect senescence differently, like epithelial cells vs neurons vs immune cells. He talks about the root of cancer being cells that escape cellular instructions. From this foundation, Dr Bitto layers in the role of mitochondria with deep explanations of metabolism as the summary of actions that cover the cycles of catabolism and anabolism- the breaking down of our food, water and oxygen intake into their individual constituents and then the process of building membranes, organelles, cells, tissues, organs, etc. He discusses the actions with the mitochondria which govern oxidative phosphorylation including the Kreb's cycle (aka Citric Acid Cycle) and the electron transport chain and the importance of membranes to govern the passage and connection of these elements to do the work. We discuss macronutrients (fats, carbohydrates and proteins) as well as the vitamins and minerals that act as co-factors. Next, Dr Bitto links mitochondrial activity with aging. Dr Bitto then shares the research he's been personally working on, which revolves around the impact on aging (in mice) by rapamycin, acarbose and butryrate. Of note, acarbose and butryrate are active in the gut and suddenly, here we see the direct link between the gut, the mitochondria, and biological aging- wow! Listen in for a ride through the science and research of metabolism, mitochondria and aging. https://www.youtube-nocookie.com/embed/acfHXTaBdgs 3657 2024-05-22T17:10:42.000Z 2026-10-22T18:43:13.662Z https://longevityharbor.com/de/watch/acfHXTaBdgs #59 Alessandro Bitto, PhD: Biological Aging, Cellular Senescence, Mitochondria & the Gut https://i.ytimg.com/vi/acfHXTaBdgs/hqdefault.jpg Dr Alessandro Bitto is a researcher at the University of Washington who studies biological aging, mitochondrial function and metabolic disease. He walks us through the history, current thinking and some of the experimental data of cellular senescence, including the role of DNA damage and telomeres, some of the senolytic drugs (quercetin, Dasatinib and others), and how different cells effect senescence differently, like epithelial cells vs neurons vs immune cells. He talks about the root of cancer being cells that escape cellular instructions. From this foundation, Dr Bitto layers in the role of mitochondria with deep explanations of metabolism as the summary of actions that cover the cycles of catabolism and anabolism- the breaking down of our food, water and oxygen intake into their individual constituents and then the process of building membranes, organelles, cells, tissues, organs, etc. He discusses the actions with the mitochondria which govern oxidative phosphorylation including the Kreb's cycle (aka Citric Acid Cycle) and the electron transport chain and the importance of membranes to govern the passage and connection of these elements to do the work. We discuss macronutrients (fats, carbohydrates and proteins) as well as the vitamins and minerals that act as co-factors. Next, Dr Bitto links mitochondrial activity with aging. Dr Bitto then shares the research he's been personally working on, which revolves around the impact on aging (in mice) by rapamycin, acarbose and butryrate. Of note, acarbose and butryrate are active in the gut and suddenly, here we see the direct link between the gut, the mitochondria, and biological aging- wow! Listen in for a ride through the science and research of metabolism, mitochondria and aging. https://www.youtube-nocookie.com/embed/acfHXTaBdgs 3657 2024-05-22T17:10:42.000Z 2026-10-22T18:43:13.662Z https://longevityharbor.com/en/watch/ahJc3LABfxc Longevity Summit 2024 - Dr. Nathan LeBrasseur https://i.ytimg.com/vi/ahJc3LABfxc/hqdefault.jpg Do you use lab testing to get to the root cause of patient health issues? Vibrant Wellness offers the largest selection of advanced specialty lab solutions, and it's free to sign up! If you're a practitioner, sign up here: Practitioner Sign-Up to order, manage, and track results from dozens of precise lab tests. Are you a patient? Achieve your health goals faster with advanced root-cause lab testing. Sign up here to get connected to a Vibrant provider: Patient Sign-Up Join Dr. Nathan LeBrasseur, a world-renowned researcher in aging and longevity, as he delivers a comprehensive talk on cellular aging, its impact on chronic diseases, and cutting-edge interventions for optimizing health span. Dr. LeBrasseur is a professor of Physical Medicine and Rehabilitation at the Mayo Clinic, where he also holds joint appointments in the Department of Physiology and Biomedical Engineering. He serves as the Director of the Robert and Arlene Kogod Center on Aging and the Co-Director of the Paul Glenn Center for Biology and Aging Research. In this presentation, Dr. LeBrasseur provides a deep dive into the biology of aging, emphasizing the role of cellular senescence and the potential of senolytics to revolutionize the way we approach age-related diseases. His groundbreaking work has earned him numerous accolades, including the Glenn Award for Aging Research, the Nathan Shock Award, and the Rising Star Award for Aging Research. Key Points 🧬 What is Cellular Aging?: Understanding the fundamental mechanisms of aging and the accumulation of senescent cells. 🧫 Senescence Explained: The role of “zombie cells” in inflammation, tissue dysfunction, and chronic disease. 💊 Senolytics and Longevity: Cutting-edge research on removing senescent cells to extend health span and delay the onset of chronic diseases. 💡 The Geroscience Hypothesis: Why targeting aging itself is the key to preventing age-related illnesses as a group. 📈 Clinical Implications: Biomarkers of aging and their application in personalized medicine and clinical tria https://www.youtube-nocookie.com/embed/ahJc3LABfxc 3788 2025-01-10T00:07:00.000Z 2026-10-22T19:54:20.357Z https://longevityharbor.com/de/watch/ahJc3LABfxc Longevity Summit 2024 - Dr. Nathan LeBrasseur https://i.ytimg.com/vi/ahJc3LABfxc/hqdefault.jpg Do you use lab testing to get to the root cause of patient health issues? Vibrant Wellness offers the largest selection of advanced specialty lab solutions, and it's free to sign up! If you're a practitioner, sign up here: Practitioner Sign-Up to order, manage, and track results from dozens of precise lab tests. Are you a patient? Achieve your health goals faster with advanced root-cause lab testing. Sign up here to get connected to a Vibrant provider: Patient Sign-Up Join Dr. Nathan LeBrasseur, a world-renowned researcher in aging and longevity, as he delivers a comprehensive talk on cellular aging, its impact on chronic diseases, and cutting-edge interventions for optimizing health span. Dr. LeBrasseur is a professor of Physical Medicine and Rehabilitation at the Mayo Clinic, where he also holds joint appointments in the Department of Physiology and Biomedical Engineering. He serves as the Director of the Robert and Arlene Kogod Center on Aging and the Co-Director of the Paul Glenn Center for Biology and Aging Research. In this presentation, Dr. LeBrasseur provides a deep dive into the biology of aging, emphasizing the role of cellular senescence and the potential of senolytics to revolutionize the way we approach age-related diseases. His groundbreaking work has earned him numerous accolades, including the Glenn Award for Aging Research, the Nathan Shock Award, and the Rising Star Award for Aging Research. Key Points 🧬 What is Cellular Aging?: Understanding the fundamental mechanisms of aging and the accumulation of senescent cells. 🧫 Senescence Explained: The role of “zombie cells” in inflammation, tissue dysfunction, and chronic disease. 💊 Senolytics and Longevity: Cutting-edge research on removing senescent cells to extend health span and delay the onset of chronic diseases. 💡 The Geroscience Hypothesis: Why targeting aging itself is the key to preventing age-related illnesses as a group. 📈 Clinical Implications: Biomarkers of aging and their application in personalized medicine and clinical tria https://www.youtube-nocookie.com/embed/ahJc3LABfxc 3788 2025-01-10T00:07:00.000Z 2026-10-22T19:54:20.357Z https://longevityharbor.com/en/watch/aixuS9GcTfs Video description: three exercises for people over 65 and claimed anti-aging effects https://i.ytimg.com/vi/aixuS9GcTfs/hqdefault.jpg The description presents the floor bridge, shadow boxing and bodyweight squat as the three exercises with the strongest research and stresses correct form; it cites a strength-training association with lower biological age and a small boxing trial. https://www.youtube-nocookie.com/embed/aixuS9GcTfs 623 2026-08-22T20:15:05.000Z 2026-10-22T22:49:09.359Z https://longevityharbor.com/de/watch/aixuS9GcTfs Videobeschreibung: drei Übungen für Menschen über 65 und behauptete Anti-Aging-Effekte https://i.ytimg.com/vi/aixuS9GcTfs/hqdefault.jpg Die Beschreibung stellt die Bodenbrücke, Schattenboxen und die Kniebeuge mit dem eigenen Körpergewicht als die drei Übungen mit der stärksten Forschungslage vor und betont die korrekte Ausführung; sie nennt einen Zusammenhang von Krafttraining mit geringerem biologischem Alter und eine kleine Box-Studie. https://www.youtube-nocookie.com/embed/aixuS9GcTfs 623 2026-08-22T20:15:05.000Z 2026-10-22T22:49:09.359Z https://longevityharbor.com/en/watch/atSwcUXQ2nM Prescriptions for Aging Well: Muscle, Strength and Protein Matter https://i.ytimg.com/vi/atSwcUXQ2nM/hqdefault.jpg As we age, many of us begin to think more seriously about how to maintain our health, independence, and quality of life. In a recent webinar, Dr. Stuart Phillips, Chair of Kinesiology at McMaster University and Canada Research Chair in Skeletal Muscle Health, shared compelling insights into how muscle, strength, and protein play a vital role in aging well. [00:00:00 Introduction] [00:01:45 Why do all living things age?] [00:04:33 What can we do to slow aging?] [00:06:30 What is sarcopenia?] [00:10:01 The importance of dietary protein and how much you really need] [00:22:36 The ‘perfect’ active aging formula] [00:37:47 Myths and facts about protein] [00:41:45 Putting it all together] [00:43:18 Plant versus animal-based protein] [00:45:11 Protein supplements] [00:46:12 Timing of your highest protein meal] [00:48:02 How can a sedentary person get started with strength training?] [00:49:51 How much strength training do I need to do, and how do the different types of resistance training compare?] [00:49:51 High-Intensity Interval Training (HIIT) and heart rate zones] [00:54:42 Collagen for muscle and joint health?] [00:59:22 Protein and strength training for bone health] [01:01:54 The role for creatine in muscle and brain health] Learn more at: Bios: Stuart Phillips, PhD, is a Canada Research Chair and Professor of Kinesiology at McMaster University and serves as the Director of the Physical Activity Centre of Excellence (PACE). He is a fellow of the Canadian Academy of Science and the American College of Sports Medicine. He is also a 5-time nominee and 3-time recipient of the McMaster Student's Union Teaching Award. His research centers on the roles exercise and nutrition play in influencing human skeletal muscle health in aging. Dr. Anthony Levinson is a Professor at McMaster University and a physician who works in the area of consultation-liaison psychiatry in Hamilton, Ontario. He leads the design and development of multimedia content, including online learning about various topics related to healthy aging fo https://www.youtube-nocookie.com/embed/atSwcUXQ2nM 3938 2025-10-01T20:46:07.000Z 2026-10-22T18:32:08.339Z https://longevityharbor.com/de/watch/atSwcUXQ2nM Prescriptions for Aging Well: Muscle, Strength and Protein Matter https://i.ytimg.com/vi/atSwcUXQ2nM/hqdefault.jpg As we age, many of us begin to think more seriously about how to maintain our health, independence, and quality of life. In a recent webinar, Dr. Stuart Phillips, Chair of Kinesiology at McMaster University and Canada Research Chair in Skeletal Muscle Health, shared compelling insights into how muscle, strength, and protein play a vital role in aging well. [00:00:00 Introduction] [00:01:45 Why do all living things age?] [00:04:33 What can we do to slow aging?] [00:06:30 What is sarcopenia?] [00:10:01 The importance of dietary protein and how much you really need] [00:22:36 The ‘perfect’ active aging formula] [00:37:47 Myths and facts about protein] [00:41:45 Putting it all together] [00:43:18 Plant versus animal-based protein] [00:45:11 Protein supplements] [00:46:12 Timing of your highest protein meal] [00:48:02 How can a sedentary person get started with strength training?] [00:49:51 How much strength training do I need to do, and how do the different types of resistance training compare?] [00:49:51 High-Intensity Interval Training (HIIT) and heart rate zones] [00:54:42 Collagen for muscle and joint health?] [00:59:22 Protein and strength training for bone health] [01:01:54 The role for creatine in muscle and brain health] Learn more at: Bios: Stuart Phillips, PhD, is a Canada Research Chair and Professor of Kinesiology at McMaster University and serves as the Director of the Physical Activity Centre of Excellence (PACE). He is a fellow of the Canadian Academy of Science and the American College of Sports Medicine. He is also a 5-time nominee and 3-time recipient of the McMaster Student's Union Teaching Award. His research centers on the roles exercise and nutrition play in influencing human skeletal muscle health in aging. Dr. Anthony Levinson is a Professor at McMaster University and a physician who works in the area of consultation-liaison psychiatry in Hamilton, Ontario. He leads the design and development of multimedia content, including online learning about various topics related to healthy aging fo https://www.youtube-nocookie.com/embed/atSwcUXQ2nM 3938 2025-10-01T20:46:07.000Z 2026-10-22T18:32:08.339Z https://longevityharbor.com/en/watch/ay2MHpyiXY4 Aging, Geroscience and Longevity Symposium – Session three https://i.ytimg.com/vi/ay2MHpyiXY4/hqdefault.jpg eLife Senior Editors Jess Tyler and Matt Kaeberlein chaired this half-day online symposium, where authors whose papers have been accepted for our upcoming Aging, Geroscience and Longevity Special Issue presented the key findings. These accepted authors presented their research through live and pre-recorded presentations. Session three includes the following speakers: 00:00:18 Michael Polymenis – Department of Biochemistry and Biophysics, Texas A&M University, United States 00:20:03 Nicole Jenkins – Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australia 00:36:33 Hosni Cherif – McGill University, Canada 00:55:18 Fivos Borbolis – Biomedical Research Foundation of the Academy of Athens, Greece 01:11:54 Ying Ann Chiao – Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, United States https://www.youtube-nocookie.com/embed/ay2MHpyiXY4 5861 2020-12-16T15:45:01.000Z 2026-10-22T17:43:40.177Z https://longevityharbor.com/de/watch/ay2MHpyiXY4 Aging, Geroscience and Longevity Symposium – Session three https://i.ytimg.com/vi/ay2MHpyiXY4/hqdefault.jpg eLife Senior Editors Jess Tyler and Matt Kaeberlein chaired this half-day online symposium, where authors whose papers have been accepted for our upcoming Aging, Geroscience and Longevity Special Issue presented the key findings. These accepted authors presented their research through live and pre-recorded presentations. Session three includes the following speakers: 00:00:18 Michael Polymenis – Department of Biochemistry and Biophysics, Texas A&M University, United States 00:20:03 Nicole Jenkins – Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australia 00:36:33 Hosni Cherif – McGill University, Canada 00:55:18 Fivos Borbolis – Biomedical Research Foundation of the Academy of Athens, Greece 01:11:54 Ying Ann Chiao – Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, United States https://www.youtube-nocookie.com/embed/ay2MHpyiXY4 5861 2020-12-16T15:45:01.000Z 2026-10-22T17:43:40.177Z https://longevityharbor.com/en/watch/b3xJBiqOsis Microcirculation? Just a Symptom. The Real Cause of Aging Is THIS https://i.ytimg.com/vi/b3xJBiqOsis/hqdefault.jpg We’ve been told aging starts with poor circulation… That shrinking blood vessels and weak blood flow are the first signs. But what if that’s all backwards? In this video, I expose the real first domino of aging — The one no mainstream theory is talking about: motor unit loss. I break down the flaws in the Microcirculatory Theory of Aging using science, logic, and the proof that lives in every movement I make at 61. If your muscles stop contracting, your blood stops circulating — period. This isn’t just about circulation. It’s about the neural command system that dies first… and takes everything else with it. Stay tuned — because I’m going to make every Hallmark of Aging crumble under the hands of motor unit integrity. 00:00 - Intro 00:33 - What the Microcirculatory Theory Claims 01:24 - The Missing First Domino 03:42 - Common Sense Test 04:24 - Muscle Is the Pump 04:54 - The Heart Isn’t Enough — Why Muscles Complete Circulation 05:23 - The Study That Proves the Link 06:40 - Microcirculation Is Not a Cause — It’s a Consequence 07:23 - The Real Cause of Systemic Aging 07:58 - The Mistake Everyone Makes 09:12 - Closing Words Disclaimer: This video is for educational and informational purposes only and reflects the personal views and experiences of the creator. It is not intended to diagnose, treat, or cure any disease or health condition. Always consult with a qualified medical professional before beginning any exercise program, supplement regimen, or health strategy. Results may vary depending on individual circumstances. References: https://www.researchgate.net/publication/15706303_Human_aging_muscle_mass_and_fiber_type_composition_J_Gerontol_A_Biol_Sci_Med_Sci - Human Aging, Muscle Mass, and Fiber Type Composition https://pmc.ncbi.nlm.nih.gov/articles/PMC6524339/ - The Relationship Between Blood Flow and Motor Unit Firing Rates in Response to Fatiguing Exercise Post-stroke https://link.springer.com/article/10.1007/s10974-019-09520-2 - The role of the microcirculation in muscle function and plastic https://www.youtube-nocookie.com/embed/b3xJBiqOsis 624 2025-04-07T23:32:49.000Z 2026-10-22T19:32:33.428Z https://longevityharbor.com/de/watch/b3xJBiqOsis Microcirculation? Just a Symptom. The Real Cause of Aging Is THIS https://i.ytimg.com/vi/b3xJBiqOsis/hqdefault.jpg We’ve been told aging starts with poor circulation… That shrinking blood vessels and weak blood flow are the first signs. But what if that’s all backwards? In this video, I expose the real first domino of aging — The one no mainstream theory is talking about: motor unit loss. I break down the flaws in the Microcirculatory Theory of Aging using science, logic, and the proof that lives in every movement I make at 61. If your muscles stop contracting, your blood stops circulating — period. This isn’t just about circulation. It’s about the neural command system that dies first… and takes everything else with it. Stay tuned — because I’m going to make every Hallmark of Aging crumble under the hands of motor unit integrity. 00:00 - Intro 00:33 - What the Microcirculatory Theory Claims 01:24 - The Missing First Domino 03:42 - Common Sense Test 04:24 - Muscle Is the Pump 04:54 - The Heart Isn’t Enough — Why Muscles Complete Circulation 05:23 - The Study That Proves the Link 06:40 - Microcirculation Is Not a Cause — It’s a Consequence 07:23 - The Real Cause of Systemic Aging 07:58 - The Mistake Everyone Makes 09:12 - Closing Words Disclaimer: This video is for educational and informational purposes only and reflects the personal views and experiences of the creator. It is not intended to diagnose, treat, or cure any disease or health condition. Always consult with a qualified medical professional before beginning any exercise program, supplement regimen, or health strategy. Results may vary depending on individual circumstances. References: https://www.researchgate.net/publication/15706303_Human_aging_muscle_mass_and_fiber_type_composition_J_Gerontol_A_Biol_Sci_Med_Sci - Human Aging, Muscle Mass, and Fiber Type Composition https://pmc.ncbi.nlm.nih.gov/articles/PMC6524339/ - The Relationship Between Blood Flow and Motor Unit Firing Rates in Response to Fatiguing Exercise Post-stroke https://link.springer.com/article/10.1007/s10974-019-09520-2 - The role of the microcirculation in muscle function and plastic https://www.youtube-nocookie.com/embed/b3xJBiqOsis 624 2025-04-07T23:32:49.000Z 2026-10-22T19:32:33.428Z https://longevityharbor.com/en/watch/b7hLGGdcKRk Meet me @ MILA - Longevity Life Hack - Best Ager machen mit! #mitmachsupermarkt #healthyaging https://i.ytimg.com/vi/b7hLGGdcKRk/hqdefault.jpg Epigenetik und gesund Altern ist die Welt von Longevity - die Gesundheit im Alter zu verlängern! Mit dem 90 Tage Epigenetik Transformation Begleitprogramm zeige ich in einer 360 Grad Betrachtung, welche Bereiche deiner Umwelt du beeinflussen kannst, um deine Gesundheit ganzheitlich zu verbessern. Buche dir ein 30 min Klarheitsgespräch kostenfrei mit Lydia: https://calendly.com/lydiafillbach/erstgespraech_epigenetik_transformation_30min Suche dir eine gute Quelle von guten Produkten und bringe dich auch persönlich ein. So wie hier zB in Wien bei MILA https://www.mila.wien/ Gerne kannst du meine Angebote hier kennen lernen: Epigenetik 90 Tage Transformation 1:1 Begleitprogramm mit Lydia https://www.lebenswert-wien.at/traumkoerper/ Gesundheitszentrum in Wien & Webshop: https://www.lebenswert-wien.at/ Human Design Mentoring 1:1 mit Lydia: https://www.lebenswert-wien.at/human-design-analyse/ Ich bin mir sicher, dass du bei mir nicht nur KLARHEIT findest, sondern auch den nächsten wichtigen IMPULS auf dem Weg zu deinem entspannt erfülltem Leben als strahlend selbstbewusstes Menschenkind :-) Deine Lydia Fillbach https://www.youtube-nocookie.com/embed/b7hLGGdcKRk 167 2025-11-14T20:26:36.000Z 2026-10-22T18:54:03.241Z https://longevityharbor.com/de/watch/b7hLGGdcKRk Meet me @ MILA - Longevity Life Hack - Best Ager machen mit! #mitmachsupermarkt #healthyaging https://i.ytimg.com/vi/b7hLGGdcKRk/hqdefault.jpg Epigenetik und gesund Altern ist die Welt von Longevity - die Gesundheit im Alter zu verlängern! Mit dem 90 Tage Epigenetik Transformation Begleitprogramm zeige ich in einer 360 Grad Betrachtung, welche Bereiche deiner Umwelt du beeinflussen kannst, um deine Gesundheit ganzheitlich zu verbessern. Buche dir ein 30 min Klarheitsgespräch kostenfrei mit Lydia: https://calendly.com/lydiafillbach/erstgespraech_epigenetik_transformation_30min Suche dir eine gute Quelle von guten Produkten und bringe dich auch persönlich ein. So wie hier zB in Wien bei MILA https://www.mila.wien/ Gerne kannst du meine Angebote hier kennen lernen: Epigenetik 90 Tage Transformation 1:1 Begleitprogramm mit Lydia https://www.lebenswert-wien.at/traumkoerper/ Gesundheitszentrum in Wien & Webshop: https://www.lebenswert-wien.at/ Human Design Mentoring 1:1 mit Lydia: https://www.lebenswert-wien.at/human-design-analyse/ Ich bin mir sicher, dass du bei mir nicht nur KLARHEIT findest, sondern auch den nächsten wichtigen IMPULS auf dem Weg zu deinem entspannt erfülltem Leben als strahlend selbstbewusstes Menschenkind :-) Deine Lydia Fillbach https://www.youtube-nocookie.com/embed/b7hLGGdcKRk 167 2025-11-14T20:26:36.000Z 2026-10-22T18:54:03.241Z https://longevityharbor.com/en/watch/b9udTP4fnVw Quarta describes senolytics as a proposed strategy against senescent cells https://i.ytimg.com/vi/b9udTP4fnVw/hqdefault.jpg In this Milan Longevity Summit 2026 session description, Dr. Marco Quarta presents senolytics as a closely watched longevity-biotechnology area: therapies aiming to selectively remove senescent cells, while noting the challenge of translating preclinical findings into safe, effective human therapies. https://www.youtube-nocookie.com/embed/b9udTP4fnVw 1268 2026-08-08T17:56:22.000Z 2026-10-22T23:08:15.066Z https://longevityharbor.com/de/watch/b9udTP4fnVw Quarta beschreibt Senolytika als vorgeschlagene Strategie gegen seneszente Zellen https://i.ytimg.com/vi/b9udTP4fnVw/hqdefault.jpg In der Beschreibung dieser Sitzung des Milan Longevity Summit 2026 stellt Dr. Marco Quarta Senolytika als viel beachtetes Gebiet der Longevity-Biotechnologie vor: Therapien, die seneszente Zellen gezielt entfernen sollen, wobei die Übersetzung präklinischer Befunde in sichere und wirksame humane Therapien eine Herausforderung bleibt. https://www.youtube-nocookie.com/embed/b9udTP4fnVw 1268 2026-08-08T17:56:22.000Z 2026-10-22T23:08:15.066Z https://longevityharbor.com/en/watch/bCEj_u2Ej6Q Can Rapamycin Extend Healthy Aging in Humans? https://i.ytimg.com/vi/bCEj_u2Ej6Q/hqdefault.jpg Among the worries that haunt retirees is possibility that retirement might be ruined by the effects of aging — softening bones, wasting muscles, creaking joints, misfiring neurons. Is there any hope that medical science might find an elixir that eliminates, or at least postpones, the onset of these curses of the elderly? Sign in to a webinar on this subject by Adam Konopka, whose research is on the biological mechanisms causing the afflictions of old age and seeks to find medications that might beneficially modify those mechanisms. https://www.youtube-nocookie.com/embed/bCEj_u2Ej6Q 3803 2025-04-30T20:28:49.000Z 2026-10-22T19:04:40.808Z https://longevityharbor.com/de/watch/bCEj_u2Ej6Q Can Rapamycin Extend Healthy Aging in Humans? https://i.ytimg.com/vi/bCEj_u2Ej6Q/hqdefault.jpg Among the worries that haunt retirees is possibility that retirement might be ruined by the effects of aging — softening bones, wasting muscles, creaking joints, misfiring neurons. Is there any hope that medical science might find an elixir that eliminates, or at least postpones, the onset of these curses of the elderly? Sign in to a webinar on this subject by Adam Konopka, whose research is on the biological mechanisms causing the afflictions of old age and seeks to find medications that might beneficially modify those mechanisms. https://www.youtube-nocookie.com/embed/bCEj_u2Ej6Q 3803 2025-04-30T20:28:49.000Z 2026-10-22T19:04:40.808Z https://longevityharbor.com/en/watch/bDIDYHJG2R4 Longevity and Preventive Medicine: An Update of the Landscape - David Barzilai https://i.ytimg.com/vi/bDIDYHJG2R4/hqdefault.jpg #LONGEVITY #HEALTHSPAN #aging Dr. David Barzilai, CEO of Healthspan Coaching, LLC, Longevity Medicine Consultant, founder of agingdoc.com was the keynote speaker at the 3rd annual Medical Affairs Innovation Olympics. He provides an update on advances in longevity and preventive medicine research, exploring promising approaches and interventions currently available with a focus on how Medical Affairs professionals can play a pivotal role in advancing these approaches. 0:00 Timeline 1:32 Dramatic Increase in Global Aging Population 2:37 Gray Tsunami Economic Impact - Rising Health Expenditures 3:32 Healthspan must accompany lifespan increase - Holy Grail of Longevity 4:30 Targeting the Bioscience of Aging: The Geroscience Hypothesis 4:47 12 Hallmarks of Aging 5:55 Problem with Current Approach of Targeting 1 Disease at a Time 6:52 Aging can be manipulated across different species Rapamycin increased lifespan even after being injected in middle aged humans 8:51 Growing Frontier in Longevity Biotech Number of biotech companies have grown from 20 to 50 since 2020 10:40 Lifestyle Medicine as Longevity Foundation 11:38 Global Strategy for Healthy Longevity Global Roadmap to Healthy Longevity National Academy of Medicine - Goal to Increase Lifespan by 6 years by 2030 12:14 Hevolution Foundation - $1 billion investment to accelerate in aging research 13:01 Bridging the gap between biotech and public health initiatives Immediate reforms in healthcare are needed such as compression of morbidity 13:39 Tackle Urgent Challenges of Aging where health is not just preserved but extended Call to Action Integrate Biotech and Public Health Strategies Invest in Aging BIology Train Physician Workforce Promise of Geroscience https://www.youtube-nocookie.com/embed/bDIDYHJG2R4 1275 2024-11-30T14:04:27.000Z 2026-10-22T19:54:20.323Z https://longevityharbor.com/de/watch/bDIDYHJG2R4 Longevity and Preventive Medicine: An Update of the Landscape - David Barzilai https://i.ytimg.com/vi/bDIDYHJG2R4/hqdefault.jpg #LONGEVITY #HEALTHSPAN #aging Dr. David Barzilai, CEO of Healthspan Coaching, LLC, Longevity Medicine Consultant, founder of agingdoc.com was the keynote speaker at the 3rd annual Medical Affairs Innovation Olympics. He provides an update on advances in longevity and preventive medicine research, exploring promising approaches and interventions currently available with a focus on how Medical Affairs professionals can play a pivotal role in advancing these approaches. 0:00 Timeline 1:32 Dramatic Increase in Global Aging Population 2:37 Gray Tsunami Economic Impact - Rising Health Expenditures 3:32 Healthspan must accompany lifespan increase - Holy Grail of Longevity 4:30 Targeting the Bioscience of Aging: The Geroscience Hypothesis 4:47 12 Hallmarks of Aging 5:55 Problem with Current Approach of Targeting 1 Disease at a Time 6:52 Aging can be manipulated across different species Rapamycin increased lifespan even after being injected in middle aged humans 8:51 Growing Frontier in Longevity Biotech Number of biotech companies have grown from 20 to 50 since 2020 10:40 Lifestyle Medicine as Longevity Foundation 11:38 Global Strategy for Healthy Longevity Global Roadmap to Healthy Longevity National Academy of Medicine - Goal to Increase Lifespan by 6 years by 2030 12:14 Hevolution Foundation - $1 billion investment to accelerate in aging research 13:01 Bridging the gap between biotech and public health initiatives Immediate reforms in healthcare are needed such as compression of morbidity 13:39 Tackle Urgent Challenges of Aging where health is not just preserved but extended Call to Action Integrate Biotech and Public Health Strategies Invest in Aging BIology Train Physician Workforce Promise of Geroscience https://www.youtube-nocookie.com/embed/bDIDYHJG2R4 1275 2024-11-30T14:04:27.000Z 2026-10-22T19:54:20.323Z https://longevityharbor.com/en/watch/bLurPJN_F0U FMD – Fasten neu gedacht mit Prof. Valter Longo & Nina Ruge https://i.ytimg.com/vi/bLurPJN_F0U/hqdefault.jpg Heute spreche ich mit Prof. Valter Longo, einem der weltweit führenden Experten für gesundes Altern und Ernährung. Bekannt wurde er durch die Entwicklung der Fasten-mimicking-Diät (FMD) – einer pflanzenbasierten 5-Tage-Ernährungsform, die die positiven Effekte des Fastens erzielt, ohne komplett auf Nahrung zu verzichten. Gemeinsam tauchen wir ein in die wissenschaftlichen Hintergründe, die beeindruckenden Ergebnisse klinischer Studien und die Frage: Wie können wir durch gezielte Ernährung länger gesund leben? In dieser Folge sprechen wir u.a. über folgende Themen: - Kann eine 5-tägige pflanzenbasierte Diät dieselben Vorteile wie klassisches Wasserfasten bringen? - Wie konnte die FMD in Studien Diabetes, Bluthochdruck und biologische Alterung positiv beeinflussen? - Wie hilft die FMD dem Körper, Fett abzubauen und gleichzeitig Muskelmasse zu erhalten? - Kann FMD beschädigte Organe wie Niere oder Bauchspeicheldrüse regenerieren? - Warum ist Wasserfasten für viele Patient:innen ungeeignet? - Welche Prozesse wie Autophagie und Ketose werden durch FMD aktiviert? - Welche Rolle spielt FMD in der Krebstherapie? - Wie beeinflussen reduzierte Aminosäuren Wachstumssignale wie IGF-1 und mTOR? - Wird es in Zukunft personalisierte FMD-Programme für bestimmte Krankheiten geben? - Warum lässt sich FMD sicher zu Hause durchführen? - Könnte FMD eine echte Alternative zu Medikamenten werden? Weitere Informationen zu Prof Valter Longo findest du hier: https://valterlongo.com/ Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder YouTube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an deinen Arzt https://www.youtube-nocookie.com/embed/bLurPJN_F0U 3236 2025-05-30T04:00:06.000Z 2026-10-22T18:32:09.015Z https://longevityharbor.com/de/watch/bLurPJN_F0U FMD – Fasten neu gedacht mit Prof. Valter Longo & Nina Ruge https://i.ytimg.com/vi/bLurPJN_F0U/hqdefault.jpg Heute spreche ich mit Prof. Valter Longo, einem der weltweit führenden Experten für gesundes Altern und Ernährung. Bekannt wurde er durch die Entwicklung der Fasten-mimicking-Diät (FMD) – einer pflanzenbasierten 5-Tage-Ernährungsform, die die positiven Effekte des Fastens erzielt, ohne komplett auf Nahrung zu verzichten. Gemeinsam tauchen wir ein in die wissenschaftlichen Hintergründe, die beeindruckenden Ergebnisse klinischer Studien und die Frage: Wie können wir durch gezielte Ernährung länger gesund leben? In dieser Folge sprechen wir u.a. über folgende Themen: - Kann eine 5-tägige pflanzenbasierte Diät dieselben Vorteile wie klassisches Wasserfasten bringen? - Wie konnte die FMD in Studien Diabetes, Bluthochdruck und biologische Alterung positiv beeinflussen? - Wie hilft die FMD dem Körper, Fett abzubauen und gleichzeitig Muskelmasse zu erhalten? - Kann FMD beschädigte Organe wie Niere oder Bauchspeicheldrüse regenerieren? - Warum ist Wasserfasten für viele Patient:innen ungeeignet? - Welche Prozesse wie Autophagie und Ketose werden durch FMD aktiviert? - Welche Rolle spielt FMD in der Krebstherapie? - Wie beeinflussen reduzierte Aminosäuren Wachstumssignale wie IGF-1 und mTOR? - Wird es in Zukunft personalisierte FMD-Programme für bestimmte Krankheiten geben? - Warum lässt sich FMD sicher zu Hause durchführen? - Könnte FMD eine echte Alternative zu Medikamenten werden? Weitere Informationen zu Prof Valter Longo findest du hier: https://valterlongo.com/ Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder YouTube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an deinen Arzt https://www.youtube-nocookie.com/embed/bLurPJN_F0U 3236 2025-05-30T04:00:06.000Z 2026-10-22T18:32:09.015Z https://longevityharbor.com/en/watch/bNC0dVf52QI Can Humans Become Physically Immortal? | Brian Kennedy, Ph.D. https://i.ytimg.com/vi/bNC0dVf52QI/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/7yNvz_0Q1eQ Become a member to receive exclusive content: https://bit.ly/3UkxydK This clip is from episode #357 ‒ A new era of longevity science: models of aging, human trials of rapamycin, biological clocks, promising compounds, and lifestyle interventions | Brian Kennedy, Ph.D. In this clip, they discuss: - Hallmarks vs. Pillars of Aging – While frameworks like “hallmarks” and “pillars” of aging provide structure, they don't explain the true cause of aging, as everything is highly interconnected - Interconnected Pathways Over Isolated Targets – Interventions like rapamycin affect multiple hallmarks, highlighting that aging is a network of interdependent processes, not separate targets - Aging Is About Homeostasis – Healthy aging is framed as the body’s ability to maintain balance and respond to damage, rather than targeting individual biological changes - Inflammation as a Central Player – In experiments, inflammation consistently emerges as a strong signal tied to aging and longevity interventions, showing up in aging clocks and biomarker analysis - Causality Between Hallmarks Is Unclear – The discussion debates whether mitochondrial dysfunction causes epigenetic changes or vice versa, reflecting the challenge in defining primary drivers -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaM https://www.youtube-nocookie.com/embed/bNC0dVf52QI 683 2025-07-22T16:01:05.000Z 2026-10-22T17:43:39.276Z https://longevityharbor.com/de/watch/bNC0dVf52QI Can Humans Become Physically Immortal? | Brian Kennedy, Ph.D. https://i.ytimg.com/vi/bNC0dVf52QI/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/7yNvz_0Q1eQ Become a member to receive exclusive content: https://bit.ly/3UkxydK This clip is from episode #357 ‒ A new era of longevity science: models of aging, human trials of rapamycin, biological clocks, promising compounds, and lifestyle interventions | Brian Kennedy, Ph.D. In this clip, they discuss: - Hallmarks vs. Pillars of Aging – While frameworks like “hallmarks” and “pillars” of aging provide structure, they don't explain the true cause of aging, as everything is highly interconnected - Interconnected Pathways Over Isolated Targets – Interventions like rapamycin affect multiple hallmarks, highlighting that aging is a network of interdependent processes, not separate targets - Aging Is About Homeostasis – Healthy aging is framed as the body’s ability to maintain balance and respond to damage, rather than targeting individual biological changes - Inflammation as a Central Player – In experiments, inflammation consistently emerges as a strong signal tied to aging and longevity interventions, showing up in aging clocks and biomarker analysis - Causality Between Hallmarks Is Unclear – The discussion debates whether mitochondrial dysfunction causes epigenetic changes or vice versa, reflecting the challenge in defining primary drivers -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaM https://www.youtube-nocookie.com/embed/bNC0dVf52QI 683 2025-07-22T16:01:05.000Z 2026-10-22T17:43:39.276Z https://longevityharbor.com/en/watch/bSH5bT8jy9k Caloric Restriction: Is it the Longevity Secret? https://i.ytimg.com/vi/bSH5bT8jy9k/hqdefault.jpg Are you a man over 30 seeking to truly boost your health, energy, and confidence as you age? Many wonder about #caloricrestriction as a path to longevity, and #DrJudsonBrandeis of #GlobalMensWellness explores this intriguing topic in our latest Short. Groundbreaking research indicates that a moderate caloric restriction, reducing daily calories by 15-25%, is significantly associated with improving cardiometabolic risk factors and measures of biological aging. This means positive changes in cholesterol, triglycerides, and lower insulin and glucose levels, alongside upregulation of autophagy, a vital cellular cleanup process. Studies like CALERIE have shown these short-term benefits can effectively slow the rate at which your body biologically ages. However, it's crucial for long-term planning to understand that there is currently no direct evidence from long-term randomized controlled trials consistently demonstrating caloric restriction leads to a greater reduction in overall mortality or age-related disease incidence over more than ten years, when compared to simply following a standard healthy diet. While short-term healthspan benefits are clear, robust evidence strongly associates consistently adhering to high-quality dietary patterns, like a Mediterranean-style diet, with a lower risk of all-cause and cardiovascular mortality. Your key takeaway: while caloric restriction shows promise for improving certain health markers, its superiority over a consistently healthy diet for actual longevity and broad disease prevention in men over 50 remains unproven and requires further research. Always consult your physician or a registered dietitian before making significant dietary changes. Like this Short, leave a comment with your thoughts, and subscribe for more expert men's health insights! Explore personalized health strategies at https://globalmenswellness.com and subscribe to The Global Men’s Wellness Podcast. #DrJudsonBrandeis #GlobalMensWellness #caloricrestriction #slowaging #longevity #antiaging #menswellnes https://www.youtube-nocookie.com/embed/bSH5bT8jy9k 146 2025-10-30T21:00:45.000Z 2026-10-22T18:32:09.969Z https://longevityharbor.com/de/watch/bSH5bT8jy9k Caloric Restriction: Is it the Longevity Secret? https://i.ytimg.com/vi/bSH5bT8jy9k/hqdefault.jpg Are you a man over 30 seeking to truly boost your health, energy, and confidence as you age? Many wonder about #caloricrestriction as a path to longevity, and #DrJudsonBrandeis of #GlobalMensWellness explores this intriguing topic in our latest Short. Groundbreaking research indicates that a moderate caloric restriction, reducing daily calories by 15-25%, is significantly associated with improving cardiometabolic risk factors and measures of biological aging. This means positive changes in cholesterol, triglycerides, and lower insulin and glucose levels, alongside upregulation of autophagy, a vital cellular cleanup process. Studies like CALERIE have shown these short-term benefits can effectively slow the rate at which your body biologically ages. However, it's crucial for long-term planning to understand that there is currently no direct evidence from long-term randomized controlled trials consistently demonstrating caloric restriction leads to a greater reduction in overall mortality or age-related disease incidence over more than ten years, when compared to simply following a standard healthy diet. While short-term healthspan benefits are clear, robust evidence strongly associates consistently adhering to high-quality dietary patterns, like a Mediterranean-style diet, with a lower risk of all-cause and cardiovascular mortality. Your key takeaway: while caloric restriction shows promise for improving certain health markers, its superiority over a consistently healthy diet for actual longevity and broad disease prevention in men over 50 remains unproven and requires further research. Always consult your physician or a registered dietitian before making significant dietary changes. Like this Short, leave a comment with your thoughts, and subscribe for more expert men's health insights! Explore personalized health strategies at https://globalmenswellness.com and subscribe to The Global Men’s Wellness Podcast. #DrJudsonBrandeis #GlobalMensWellness #caloricrestriction #slowaging #longevity #antiaging #menswellnes https://www.youtube-nocookie.com/embed/bSH5bT8jy9k 146 2025-10-30T21:00:45.000Z 2026-10-22T18:32:09.969Z https://longevityharbor.com/en/watch/bW0GlMmR6S0 Fasting (Without Calorie Restriction) And Calorie Restriction With Fasting Extend Lifespan https://i.ytimg.com/vi/bW0GlMmR6S0/hqdefault.jpg Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD Discount Links/Affiliates: Blood testing (where I get my labs): https://www.ultalabtests.com/partners/michaellustgarten At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten Use Code: CONQUERAGING At Checkout Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ62UkAVXBWtRVKJUM0&irgwc=1 Use Code: CONQUERAGING NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/ Use Code: ConquerAging At Checkout Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten Enter Code: ConquerAging SiphoxHealth Blood Testing (ApoB, GrimAge): https://getquantify.io/mlustgarten Green Tea: https://www.ochaandco.com/?ref=fqbtflod Use Code: ML10OFF Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack= If you'd like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/ --------------------------------------------------------------------------------------------------------------------------- Papers referenced in the video: Dietary restriction impacts health and lifespan of genetically diverse mice https://www.nature.com/articles/s41586-024-08026-3 Incidental lymphopenia and mortality: a prospective cohort study https://pubmed.ncbi.nlm.nih.gov/31932337/ Red cell distribution width associations with clinical outcomes: A population-based cohort study https://pubmed.ncbi.nlm.nih.gov/30865651/ https://www.youtube-nocookie.com/embed/bW0GlMmR6S0 742 2024-10-27T11:00:41.000Z 2026-10-22T17:43:38.430Z https://longevityharbor.com/de/watch/bW0GlMmR6S0 Fasting (Without Calorie Restriction) And Calorie Restriction With Fasting Extend Lifespan https://i.ytimg.com/vi/bW0GlMmR6S0/hqdefault.jpg Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD Discount Links/Affiliates: Blood testing (where I get my labs): https://www.ultalabtests.com/partners/michaellustgarten At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten Use Code: CONQUERAGING At Checkout Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ62UkAVXBWtRVKJUM0&irgwc=1 Use Code: CONQUERAGING NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/ Use Code: ConquerAging At Checkout Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten Enter Code: ConquerAging SiphoxHealth Blood Testing (ApoB, GrimAge): https://getquantify.io/mlustgarten Green Tea: https://www.ochaandco.com/?ref=fqbtflod Use Code: ML10OFF Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack= If you'd like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/ --------------------------------------------------------------------------------------------------------------------------- Papers referenced in the video: Dietary restriction impacts health and lifespan of genetically diverse mice https://www.nature.com/articles/s41586-024-08026-3 Incidental lymphopenia and mortality: a prospective cohort study https://pubmed.ncbi.nlm.nih.gov/31932337/ Red cell distribution width associations with clinical outcomes: A population-based cohort study https://pubmed.ncbi.nlm.nih.gov/30865651/ https://www.youtube-nocookie.com/embed/bW0GlMmR6S0 742 2024-10-27T11:00:41.000Z 2026-10-22T17:43:38.430Z https://longevityharbor.com/en/watch/bWrbuystWoI Video description: exercise and healthy aging, per Dr. Vellaichamy https://i.ytimg.com/vi/bWrbuystWoI/hqdefault.jpg In the description, Dr. Muthukumar Vellaichamy of KSP Health presents exercise as preventive and therapeutic medicine for aging-related conditions, based on a 2025 journal consensus. The description was reviewed; the video and transcript were not. https://www.youtube-nocookie.com/embed/bWrbuystWoI 885 2026-06-29T15:35:17.000Z 2026-10-22T23:42:09.575Z https://longevityharbor.com/de/watch/bWrbuystWoI Videobeschreibung: Bewegung und gesundes Altern laut Dr. Vellaichamy https://i.ytimg.com/vi/bWrbuystWoI/hqdefault.jpg In der Beschreibung stellt Dr. Muthukumar Vellaichamy von KSP Health Bewegung als vorbeugende und therapeutische Medizin bei altersbezogenen Zuständen dar, gestützt auf einen Zeitschriftenkonsens von 2025. Die Beschreibung wurde geprüft; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/bWrbuystWoI 885 2026-06-29T15:35:17.000Z 2026-10-22T23:42:09.575Z https://longevityharbor.com/en/watch/bYyT3TnExTU Video description: diet, visceral fat and aging topics, not a study report https://i.ytimg.com/vi/bYyT3TnExTU/hqdefault.jpg The description lists chapters on aging hallmarks, a Spanish keto-Mediterranean study on visceral fat, omega-3s and muscle protein synthesis, protein needs, Mediterranean carbs and early fatty liver signs. It reports no results. https://www.youtube-nocookie.com/embed/bYyT3TnExTU 1037 2026-08-26T14:20:51.000Z 2026-10-22T22:42:07.967Z https://longevityharbor.com/de/watch/bYyT3TnExTU Videobeschreibung: Ernährung, viszerales Fett und Altern, kein Studienbericht https://i.ytimg.com/vi/bYyT3TnExTU/hqdefault.jpg Die Beschreibung listet Kapitel zu Hallmarks des Alterns, einer spanischen Keto-Mittelmeer-Studie zu viszeralem Fett, Omega-3-Fettsäuren und Muskelproteinsynthese, Proteinbedarf, Mittelmeer-Kohlenhydraten und frühen Fettleberzeichen. Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/bYyT3TnExTU 1037 2026-08-26T14:20:51.000Z 2026-10-22T22:42:07.967Z https://longevityharbor.com/en/watch/bl17zdgAwWA Satchin Panda: The Age of Circadian Disruption https://i.ytimg.com/vi/bl17zdgAwWA/hqdefault.jpg Our modern world is full of potential disruptions to sleep. But as we learn more about circadian rhythm, we find that it influences everything from metabolism to mental health in different ways as we age. In this episode, Satchin Panda of the Salk Institute guides Gordon through the many interactions between sleep behavior and biology. Together they explore how new insights can help us improve our sleep health, and how researchers might target circadian rhythm to modulate the effects of aging. Satchin Panda, PhD, is a leading expert in the field of circadian rhythm research. He is a professor at the Salk Institute for Biological Studies and a founding executive member of the Center for Circadian Biology at the University of California, San Diego. Dr. Panda is a Pew Biomedical Scholar and a recipient of the Julie Martin Mid-Career Award in Aging Research. As a recognition of the impact of his work regarding circadian rhythms and diabetes, Dr. Panda has been invited to speak at conferences around the world, including Diabetes UK, the American Diabetes Association, the Danish Diabetes Association, and the respective professional diabetes societies of Europe and Australia. He is the author of The Circadian Code: Lose Weight, Supercharge Your Energy, and Transform Your Health from Morning to Midnight. Support the show (https://www.buckinstitute.org/donate/) https://www.youtube-nocookie.com/embed/bl17zdgAwWA 1864 2024-04-17T12:20:10.000Z 2026-10-22T18:54:01.981Z https://longevityharbor.com/de/watch/bl17zdgAwWA Satchin Panda: The Age of Circadian Disruption https://i.ytimg.com/vi/bl17zdgAwWA/hqdefault.jpg Our modern world is full of potential disruptions to sleep. But as we learn more about circadian rhythm, we find that it influences everything from metabolism to mental health in different ways as we age. In this episode, Satchin Panda of the Salk Institute guides Gordon through the many interactions between sleep behavior and biology. Together they explore how new insights can help us improve our sleep health, and how researchers might target circadian rhythm to modulate the effects of aging. Satchin Panda, PhD, is a leading expert in the field of circadian rhythm research. He is a professor at the Salk Institute for Biological Studies and a founding executive member of the Center for Circadian Biology at the University of California, San Diego. Dr. Panda is a Pew Biomedical Scholar and a recipient of the Julie Martin Mid-Career Award in Aging Research. As a recognition of the impact of his work regarding circadian rhythms and diabetes, Dr. Panda has been invited to speak at conferences around the world, including Diabetes UK, the American Diabetes Association, the Danish Diabetes Association, and the respective professional diabetes societies of Europe and Australia. He is the author of The Circadian Code: Lose Weight, Supercharge Your Energy, and Transform Your Health from Morning to Midnight. Support the show (https://www.buckinstitute.org/donate/) https://www.youtube-nocookie.com/embed/bl17zdgAwWA 1864 2024-04-17T12:20:10.000Z 2026-10-22T18:54:01.981Z https://longevityharbor.com/en/watch/bmDQes1U1qc What Epigenetics Can Tell Us About Aging with Professor Steve Horvath https://i.ytimg.com/vi/bmDQes1U1qc/hqdefault.jpg In this episode, Professor Steve Horvath, an influential biostatistics and human genetics researcher, dives into the revolutionary world of epigenetic clocks. He explains how he uses DNA methylation data to develop clocks that offer unprecedented precision in predicting both chronological and biological age. Prof. Horvath also discusses how epigenetic clocks can reveal significant disparities between an individual's biological and chronological age, influenced by factors such as diet, lifestyle, and environment. The episode explores epigenetic clocks’ far-reaching implications for targeted interventions, disease prevention, longevity, and our understanding of core aging processes. Note: This lecture was recorded in March 2022. Learn more about Professor Steve Horvath’s work: https://www.altoslabs.com/team/steve-horvath Learn more about Dr. David Dodick: https://www.atria.org/doctors/dr-david-w-dodick/ Time stamps: 00:00:17: Intro 00:03:00: Steve Horvath introduces the ideas of epigenetic clocks and innate aging 00:04:48: Molecular vs. clinical biomarkers of aging 00:09:20: How to measure biological age 00:11:06: Four axioms of biological age 00:13:40: DNA methylation 00:17:58: Epigenetic clocks as prediction methods 00:24:50: The limitation of using blood as a surrogate for other tissues when measuring aging 00:26:30: Epigenetic age acceleration in different organs and related conditions 00:28:11: Developing an epigenetic clock for primates 00:30:39: Creating a pan-mammalian clock and other species-specific clocks 00:33:13: What is the age of stem cells? 00:36:16: The use of epigenetic clocks in patient care 00:40:07: The effect of lifestyle factors on grim age 00:45:34: How epigenetic clocks enhance the predicting power of other biomarkers 00:46:49: Impact of different interventions on aging 00:49:40: Results of clinical trials on epigenetic aging 00:58:01: Relation between stress and age acceleration 01:00:19: Exploring Clonal hematopoiesis of indeterminate potential (CHIP) and epigenetic age accelera https://www.youtube-nocookie.com/embed/bmDQes1U1qc 4079 2025-04-07T04:00:36.000Z 2026-10-22T17:43:35.343Z https://longevityharbor.com/de/watch/bmDQes1U1qc What Epigenetics Can Tell Us About Aging with Professor Steve Horvath https://i.ytimg.com/vi/bmDQes1U1qc/hqdefault.jpg In this episode, Professor Steve Horvath, an influential biostatistics and human genetics researcher, dives into the revolutionary world of epigenetic clocks. He explains how he uses DNA methylation data to develop clocks that offer unprecedented precision in predicting both chronological and biological age. Prof. Horvath also discusses how epigenetic clocks can reveal significant disparities between an individual's biological and chronological age, influenced by factors such as diet, lifestyle, and environment. The episode explores epigenetic clocks’ far-reaching implications for targeted interventions, disease prevention, longevity, and our understanding of core aging processes. Note: This lecture was recorded in March 2022. Learn more about Professor Steve Horvath’s work: https://www.altoslabs.com/team/steve-horvath Learn more about Dr. David Dodick: https://www.atria.org/doctors/dr-david-w-dodick/ Time stamps: 00:00:17: Intro 00:03:00: Steve Horvath introduces the ideas of epigenetic clocks and innate aging 00:04:48: Molecular vs. clinical biomarkers of aging 00:09:20: How to measure biological age 00:11:06: Four axioms of biological age 00:13:40: DNA methylation 00:17:58: Epigenetic clocks as prediction methods 00:24:50: The limitation of using blood as a surrogate for other tissues when measuring aging 00:26:30: Epigenetic age acceleration in different organs and related conditions 00:28:11: Developing an epigenetic clock for primates 00:30:39: Creating a pan-mammalian clock and other species-specific clocks 00:33:13: What is the age of stem cells? 00:36:16: The use of epigenetic clocks in patient care 00:40:07: The effect of lifestyle factors on grim age 00:45:34: How epigenetic clocks enhance the predicting power of other biomarkers 00:46:49: Impact of different interventions on aging 00:49:40: Results of clinical trials on epigenetic aging 00:58:01: Relation between stress and age acceleration 01:00:19: Exploring Clonal hematopoiesis of indeterminate potential (CHIP) and epigenetic age accelera https://www.youtube-nocookie.com/embed/bmDQes1U1qc 4079 2025-04-07T04:00:36.000Z 2026-10-22T17:43:35.343Z https://longevityharbor.com/en/watch/bmVfj_yoc5Y Video description: epigenetic clocks are correlations, not direct biological age measures https://i.ytimg.com/vi/bmVfj_yoc5Y/hqdefault.jpg The description says epigenetic clocks are a correlation to a correlation to biological age, not direct measures, and advises caution, especially with consumer versions. https://www.youtube-nocookie.com/embed/bmVfj_yoc5Y 90 2026-06-13T03:03:19.000Z 2026-10-22T23:59:32.184Z https://longevityharbor.com/de/watch/bmVfj_yoc5Y Videobeschreibung: epigenetische Uhren sind Korrelationen, keine direkten Messungen des biologischen https://i.ytimg.com/vi/bmVfj_yoc5Y/hqdefault.jpg Die Beschreibung sagt, epigenetische Uhren seien eine Korrelation einer Korrelation mit dem biologischen Alter, keine direkten Messungen, und rät besonders bei Verbraucherversionen zur Vorsicht. https://www.youtube-nocookie.com/embed/bmVfj_yoc5Y 90 2026-06-13T03:03:19.000Z 2026-10-22T23:59:32.184Z https://longevityharbor.com/en/watch/bo_XASKmr8k I used to think #eating less was the answer #FastingMimickingDiet #fasting #Longevity #shorts https://i.ytimg.com/vi/bo_XASKmr8k/hqdefault.jpg Curious if FMD is right for you? Comment "MetabolicSwitch" to learn how it works and see if it's a fit for your goals. 👉 Follow us for more tips on smarter nutrition! https://www.youtube-nocookie.com/embed/bo_XASKmr8k 90 2025-09-30T14:15:05.000Z 2026-10-22T19:32:30.620Z https://longevityharbor.com/de/watch/bo_XASKmr8k I used to think #eating less was the answer #FastingMimickingDiet #fasting #Longevity #shorts https://i.ytimg.com/vi/bo_XASKmr8k/hqdefault.jpg Curious if FMD is right for you? Comment "MetabolicSwitch" to learn how it works and see if it's a fit for your goals. 👉 Follow us for more tips on smarter nutrition! https://www.youtube-nocookie.com/embed/bo_XASKmr8k 90 2025-09-30T14:15:05.000Z 2026-10-22T19:32:30.620Z https://longevityharbor.com/en/watch/bomWMas1Gno Video description: meta-review of over 100 studies on NAD levels and ageing https://i.ytimg.com/vi/bomWMas1Gno/hqdefault.jpg The description says a meta-review of over 100 studies examined NAD levels with ageing and suggests cells running out of fuel may be a major driver of ageing. It does not report results, participants or outcomes. https://www.youtube-nocookie.com/embed/bomWMas1Gno 99 2026-02-11T11:00:11.000Z 2026-10-23T02:35:38.449Z https://longevityharbor.com/de/watch/bomWMas1Gno Videobeschreibung: Meta-Review über 100 Studien zu NAD-Spiegeln und Altern https://i.ytimg.com/vi/bomWMas1Gno/hqdefault.jpg Laut Beschreibung untersuchte ein Meta-Review über 100 Studien NAD-Spiegel im Zusammenhang mit dem Altern und legt nahe, dass Zellen, denen der Brennstoff ausgeht, ein wichtiger Alterungstreiber sein könnten. Ergebnisse, Teilnehmende oder Endpunkte werden nicht berichtet. https://www.youtube-nocookie.com/embed/bomWMas1Gno 99 2026-02-11T11:00:11.000Z 2026-10-23T02:35:38.449Z https://longevityharbor.com/en/watch/bqe0ZGM4U1g Creatine for brain energy, mood and healthy aging: a video description overview https://i.ytimg.com/vi/bqe0ZGM4U1g/hqdefault.jpg The description says Dr. Josh Axe discusses creatine for brain energy, mood, bone strength, mitochondrial health and healthy aging, and why women and adults over 50 may benefit most. https://www.youtube-nocookie.com/embed/bqe0ZGM4U1g 1761 2026-07-20T11:00:07.000Z 2026-10-22T23:27:52.342Z https://longevityharbor.com/de/watch/bqe0ZGM4U1g Kreatin für Hirnenergie, Stimmung und gesundes Altern: ein Überblick zur Videobeschreibung https://i.ytimg.com/vi/bqe0ZGM4U1g/hqdefault.jpg Laut Beschreibung erläutert Dr. Josh Axe Kreatin im Zusammenhang mit Hirnenergie, Stimmung, Knochenstärke, Mitochondrien und gesundem Altern sowie mögliche Vorteile für Frauen und Erwachsene über 50. https://www.youtube-nocookie.com/embed/bqe0ZGM4U1g 1761 2026-07-20T11:00:07.000Z 2026-10-22T23:27:52.342Z https://longevityharbor.com/en/watch/buKdI2SxQ1s Forget Candles on the Cake — Epigenetic Clocks Tell Your Real Age Now https://i.ytimg.com/vi/buKdI2SxQ1s/hqdefault.jpg #EpigeneticClock #BiologicalAge #Longevity #AntiAging #EpigeneticTest https://www.youtube-nocookie.com/embed/buKdI2SxQ1s 232 2026-08-02T08:45:18.000Z 2026-10-22T17:43:35.339Z https://longevityharbor.com/de/watch/buKdI2SxQ1s Forget Candles on the Cake — Epigenetic Clocks Tell Your Real Age Now https://i.ytimg.com/vi/buKdI2SxQ1s/hqdefault.jpg #EpigeneticClock #BiologicalAge #Longevity #AntiAging #EpigeneticTest https://www.youtube-nocookie.com/embed/buKdI2SxQ1s 232 2026-08-02T08:45:18.000Z 2026-10-22T17:43:35.339Z https://longevityharbor.com/en/watch/bve2w48Op9o Senolytics vs Senomorphics: What’s The Difference & Which One To Take? | Aging & Senescence https://i.ytimg.com/vi/bve2w48Op9o/hqdefault.jpg Senolytics and senomorphics are two innovative and emerging approaches in the realm of cellular senescence research, focusing on the effective treatment of senescent cells that are known to significantly contribute to aging and various age-related diseases. While senolytics aim to eliminate these harmful cells, senomorphics work to modulate their negative effects. Understanding the difference between senolytics and senomorphics is crucial for anyone deeply interested in advancing their knowledge in aging research and therapeutic interventions. This video is taken from a podcast featuring our honored guest, Dr. Morgan Camp, who shares his valuable expertise on the implications of senolytics vs senomorphics in modern medicine. Dr. Camp discusses how these innovative therapies function and their potential benefits in treating various conditions associated with aging, providing important insights into their application in contemporary healthcare. 👇👇👇 Link To Full Podcast: https://www.youtube.com/watch?v=usoB4rCScew In this video, we explore the fascinating relationship between rapamycin and kidney health, focusing on how senolytic and senomorphic therapies can influence patient outcomes and overall health. The engaging conversation highlights key differences between the two approaches, their unique mechanisms of action, and recent advancements in senescent cell studies and senescent cell & senolytics in human trials that are reshaping the field. With the growing interest in senotherapeutics and their transformative potential, understanding these therapies’ unique roles and applications is essential. This informative video addresses the challenges and exciting opportunities associated with senolytics and senomorphics, offering a well-rounded perspective on their potential to improve health outcomes for aging individuals. 00:00 Intro 00:42 Relation between Rapamycin and Kidney Disease 03:23 Senolytic VS Senomorphic 08:52 Outro Overall, this video provides valuable insights into the roles of senolytics vs s https://www.youtube-nocookie.com/embed/bve2w48Op9o 581 2024-10-29T13:00:54.000Z 2026-10-22T19:43:47.805Z https://longevityharbor.com/de/watch/bve2w48Op9o Senolytics vs Senomorphics: What’s The Difference & Which One To Take? | Aging & Senescence https://i.ytimg.com/vi/bve2w48Op9o/hqdefault.jpg Senolytics and senomorphics are two innovative and emerging approaches in the realm of cellular senescence research, focusing on the effective treatment of senescent cells that are known to significantly contribute to aging and various age-related diseases. While senolytics aim to eliminate these harmful cells, senomorphics work to modulate their negative effects. Understanding the difference between senolytics and senomorphics is crucial for anyone deeply interested in advancing their knowledge in aging research and therapeutic interventions. This video is taken from a podcast featuring our honored guest, Dr. Morgan Camp, who shares his valuable expertise on the implications of senolytics vs senomorphics in modern medicine. Dr. Camp discusses how these innovative therapies function and their potential benefits in treating various conditions associated with aging, providing important insights into their application in contemporary healthcare. 👇👇👇 Link To Full Podcast: https://www.youtube.com/watch?v=usoB4rCScew In this video, we explore the fascinating relationship between rapamycin and kidney health, focusing on how senolytic and senomorphic therapies can influence patient outcomes and overall health. The engaging conversation highlights key differences between the two approaches, their unique mechanisms of action, and recent advancements in senescent cell studies and senescent cell & senolytics in human trials that are reshaping the field. With the growing interest in senotherapeutics and their transformative potential, understanding these therapies’ unique roles and applications is essential. This informative video addresses the challenges and exciting opportunities associated with senolytics and senomorphics, offering a well-rounded perspective on their potential to improve health outcomes for aging individuals. 00:00 Intro 00:42 Relation between Rapamycin and Kidney Disease 03:23 Senolytic VS Senomorphic 08:52 Outro Overall, this video provides valuable insights into the roles of senolytics vs s https://www.youtube-nocookie.com/embed/bve2w48Op9o 581 2024-10-29T13:00:54.000Z 2026-10-22T19:43:47.805Z https://longevityharbor.com/en/watch/bytnIaU5rqk Steve Horvath | Epigenetic Clocks for Clinical and Preclinical Applications https://i.ytimg.com/vi/bytnIaU5rqk/hqdefault.jpg Dr. Steve Horvath is very well known in the field for his groundbreaking work on epigenetic clocks, which use one of the hallmarks of aging, epigenetic alterations, in order to calculate biological age. In his talk at Ending Age-Related Diseases 2020, he discusses how such clocks can be used to evaluate the effectiveness of rejuvenation biotechnology therapies, providing useful clinical endpoints that don't involve waiting for people to age and die. In collaboration with other researchers, he recently published a scientific paper on this topic, and our discussion of it is available at https://www.lifespan.io/news/grimage-is-the-best-clock-for-predicting-death/ HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech https://www.youtube-nocookie.com/embed/bytnIaU5rqk 1449 2020-12-01T15:51:19.000Z 2026-10-22T17:43:35.267Z https://longevityharbor.com/de/watch/bytnIaU5rqk Steve Horvath | Epigenetic Clocks for Clinical and Preclinical Applications https://i.ytimg.com/vi/bytnIaU5rqk/hqdefault.jpg Dr. Steve Horvath is very well known in the field for his groundbreaking work on epigenetic clocks, which use one of the hallmarks of aging, epigenetic alterations, in order to calculate biological age. In his talk at Ending Age-Related Diseases 2020, he discusses how such clocks can be used to evaluate the effectiveness of rejuvenation biotechnology therapies, providing useful clinical endpoints that don't involve waiting for people to age and die. In collaboration with other researchers, he recently published a scientific paper on this topic, and our discussion of it is available at https://www.lifespan.io/news/grimage-is-the-best-clock-for-predicting-death/ HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech https://www.youtube-nocookie.com/embed/bytnIaU5rqk 1449 2020-12-01T15:51:19.000Z 2026-10-22T17:43:35.267Z https://longevityharbor.com/en/watch/c-1olaHS8VM Epigenetic Age Clock Test Case Study https://i.ytimg.com/vi/c-1olaHS8VM/hqdefault.jpg WellLab website: www.MalaysiaLaboratory.com WellLab email: Laboratory@Psychology.com.my For more info on Nutritional & Functional Medicine: https://nutrimed.club/ Tel: +60327277434 https://www.youtube-nocookie.com/embed/c-1olaHS8VM 3001 2024-04-02T08:04:32.000Z 2026-10-22T19:43:51.876Z https://longevityharbor.com/de/watch/c-1olaHS8VM Epigenetic Age Clock Test Case Study https://i.ytimg.com/vi/c-1olaHS8VM/hqdefault.jpg WellLab website: www.MalaysiaLaboratory.com WellLab email: Laboratory@Psychology.com.my For more info on Nutritional & Functional Medicine: https://nutrimed.club/ Tel: +60327277434 https://www.youtube-nocookie.com/embed/c-1olaHS8VM 3001 2024-04-02T08:04:32.000Z 2026-10-22T19:43:51.876Z https://longevityharbor.com/en/watch/c06dTj0v0sM Nutrition for a Healthy Life https://i.ytimg.com/vi/c06dTj0v0sM/hqdefault.jpg Constant exposure to our environment, the things we eat, and stresses from both inside and outside our bodies all cause us to age over time. This film explores those biological processes of aging, how we can maintain health throughout our lives with healthy lifestyles, and how scientists are learning more about the specific nutrients that can positively impact health. Learn more about agingresearch.org/NutritionFilms https://www.youtube-nocookie.com/embed/c06dTj0v0sM 266 2016-03-07T17:39:41.000Z 2026-10-23T01:53:57.189Z https://longevityharbor.com/de/watch/c06dTj0v0sM Nutrition for a Healthy Life https://i.ytimg.com/vi/c06dTj0v0sM/hqdefault.jpg Constant exposure to our environment, the things we eat, and stresses from both inside and outside our bodies all cause us to age over time. This film explores those biological processes of aging, how we can maintain health throughout our lives with healthy lifestyles, and how scientists are learning more about the specific nutrients that can positively impact health. Learn more about agingresearch.org/NutritionFilms https://www.youtube-nocookie.com/embed/c06dTj0v0sM 266 2016-03-07T17:39:41.000Z 2026-10-23T01:53:57.189Z https://longevityharbor.com/en/watch/c0pdoazgNn8 Overview of Cell Senescence https://i.ytimg.com/vi/c0pdoazgNn8/hqdefault.jpg Researchers have found that senescent cells accumulate in our body as we age. Deciphering the purpose, causes, and consequences of cellular senescence will provide us with a better understanding of the role they may play in a wide variety of diseases and how we can use therapies to remove them to improve human health. This video is part of the Research Integrated Science Education (RISE) Program that is funded by SENS Research Foundation and Dalio Philanthropies. The program is designed to introduce high school students to aging research and laboratory concepts, such as experimental design and data interpretation, within core curriculum standards. To learn more about RISE and to access additional functionalities such as the transcript glossary function, visit https://www.sens.org/rise https://www.youtube-nocookie.com/embed/c0pdoazgNn8 341 2020-11-30T23:32:00.000Z 2026-10-23T02:24:27.159Z https://longevityharbor.com/de/watch/c0pdoazgNn8 Overview of Cell Senescence https://i.ytimg.com/vi/c0pdoazgNn8/hqdefault.jpg Researchers have found that senescent cells accumulate in our body as we age. Deciphering the purpose, causes, and consequences of cellular senescence will provide us with a better understanding of the role they may play in a wide variety of diseases and how we can use therapies to remove them to improve human health. This video is part of the Research Integrated Science Education (RISE) Program that is funded by SENS Research Foundation and Dalio Philanthropies. The program is designed to introduce high school students to aging research and laboratory concepts, such as experimental design and data interpretation, within core curriculum standards. To learn more about RISE and to access additional functionalities such as the transcript glossary function, visit https://www.sens.org/rise https://www.youtube-nocookie.com/embed/c0pdoazgNn8 341 2020-11-30T23:32:00.000Z 2026-10-23T02:24:27.159Z https://longevityharbor.com/en/watch/c1ufPjHVibU The Effects of Senolytics in Animal Models of PF | Cory Hogaboam, PhD https://i.ytimg.com/vi/c1ufPjHVibU/hqdefault.jpg Cory Hogaboam, PhD of Cedars-Sinai discusses the several mechanisms that appear to account for cellular senescence in IPF as well as the benefits, consequences, and future challenges of cellular senescence. Social media platforms - Twitter - @PFFORG Facebook - @PFFORG Instagram - @PFFORG LinkedIn- Pulmonary Fibrosis Foundation Please note that any information contained in this presentation is for informational and/or educational purposes only. It is not intended to be a substitute for professional medical advice. Always consult your personal physician or health care provider with any questions you may have regarding your specific medical condition. This presentation is protected by U.S. and International copyright laws. Reproductions and distribution of this presentation without written permission from the Pulmonary Fibrosis Foundation is prohibited. © 2020 Pulmonary Fibrosis Foundation https://www.youtube-nocookie.com/embed/c1ufPjHVibU 1136 2020-02-13T21:00:05.000Z 2026-10-23T02:56:02.680Z https://longevityharbor.com/de/watch/c1ufPjHVibU The Effects of Senolytics in Animal Models of PF | Cory Hogaboam, PhD https://i.ytimg.com/vi/c1ufPjHVibU/hqdefault.jpg Cory Hogaboam, PhD of Cedars-Sinai discusses the several mechanisms that appear to account for cellular senescence in IPF as well as the benefits, consequences, and future challenges of cellular senescence. Social media platforms - Twitter - @PFFORG Facebook - @PFFORG Instagram - @PFFORG LinkedIn- Pulmonary Fibrosis Foundation Please note that any information contained in this presentation is for informational and/or educational purposes only. It is not intended to be a substitute for professional medical advice. Always consult your personal physician or health care provider with any questions you may have regarding your specific medical condition. This presentation is protected by U.S. and International copyright laws. Reproductions and distribution of this presentation without written permission from the Pulmonary Fibrosis Foundation is prohibited. © 2020 Pulmonary Fibrosis Foundation https://www.youtube-nocookie.com/embed/c1ufPjHVibU 1136 2020-02-13T21:00:05.000Z 2026-10-23T02:56:02.680Z https://longevityharbor.com/en/watch/c3YA08pqVJM [SHORTS] 🌟 Muscle: The Forgotten Longevity Organ — Why Lean Mass Matters More Than You Think! 🌟 https://i.ytimg.com/vi/c3YA08pqVJM/hqdefault.jpg Want to live better, longer, and stronger? 🌟 Dive into expert doctor tips, powerful stress management hacks, and game-changing medical advice that elevate your mind and body. Discover the truth about anti-aging, executive health, and workplace wellness—all backed by cutting-edge functional medicine, longevity research, and smart preventive health strategies. Your journey to lasting energy, sharp focus, and unstoppable wellness starts now! 💪✨ Did you know your muscle isn’t just for strength or looks — it’s one of the most powerful longevity organs in your body? In this Thrivespan Elite video, we dive deep into how lean mass protects you from aging, frailty, chronic disease, and metabolic decline. Discover how maintaining and building muscle can: ✔️ Strengthen your immune system ✔️ Improve metabolic health ✔️ Reduce inflammation ✔️ Boost mobility and independence ✔️ Extend your healthy lifespan If you want to live longer and live better, this is the science-backed guide you don’t want to miss. 💪✨ 👉 Watch now and start your muscle-protection journey today! #Longevity, #LeanMass, #HealthyAging, #MuscleHealth, #ThrivespanElite, #AntiAging, #FrailtyPrevention, #MetabolicHealth, #BuildMuscle, #HealthTips, #WellnessScience, #FitnessForLife, #StrengthTraining, #AgingWell, #LifespanBoost https://www.youtube-nocookie.com/embed/c3YA08pqVJM 174 2025-11-17T17:01:07.000Z 2026-10-22T19:54:15.565Z https://longevityharbor.com/de/watch/c3YA08pqVJM [SHORTS] 🌟 Muscle: The Forgotten Longevity Organ — Why Lean Mass Matters More Than You Think! 🌟 https://i.ytimg.com/vi/c3YA08pqVJM/hqdefault.jpg Want to live better, longer, and stronger? 🌟 Dive into expert doctor tips, powerful stress management hacks, and game-changing medical advice that elevate your mind and body. Discover the truth about anti-aging, executive health, and workplace wellness—all backed by cutting-edge functional medicine, longevity research, and smart preventive health strategies. Your journey to lasting energy, sharp focus, and unstoppable wellness starts now! 💪✨ Did you know your muscle isn’t just for strength or looks — it’s one of the most powerful longevity organs in your body? In this Thrivespan Elite video, we dive deep into how lean mass protects you from aging, frailty, chronic disease, and metabolic decline. Discover how maintaining and building muscle can: ✔️ Strengthen your immune system ✔️ Improve metabolic health ✔️ Reduce inflammation ✔️ Boost mobility and independence ✔️ Extend your healthy lifespan If you want to live longer and live better, this is the science-backed guide you don’t want to miss. 💪✨ 👉 Watch now and start your muscle-protection journey today! #Longevity, #LeanMass, #HealthyAging, #MuscleHealth, #ThrivespanElite, #AntiAging, #FrailtyPrevention, #MetabolicHealth, #BuildMuscle, #HealthTips, #WellnessScience, #FitnessForLife, #StrengthTraining, #AgingWell, #LifespanBoost https://www.youtube-nocookie.com/embed/c3YA08pqVJM 174 2025-11-17T17:01:07.000Z 2026-10-22T19:54:15.565Z https://longevityharbor.com/en/watch/c5n1X0u5e9g Does Exercise Actually Reverse Prediabetes? #prediabetes #fitnessscience #diabetes https://i.ytimg.com/vi/c5n1X0u5e9g/hqdefault.jpg Prediabetes acts as a silent warning sign that you might be in greater danger than you realize. Learn how to stop the progression. Many people view prediabetes as a minor health concern, but leaving it unchecked can lead to serious issues like heart disease and nerve damage. This video breaks down the reality of your body struggling to keep up and why immediate action is necessary to protect your long-term health. We examine research, including a 2019 meta-analysis, showing that regular exercise benefits your system significantly. By combining physical activity with a plant-rich diet, you can actively lower blood sugar levels and work to prevent type 2 diabetes before it becomes a permanent diagnosis. Subscribe for weekly health and fitness breakdowns, and comment below with your biggest question about managing blood sugar levels. About the Channel: Evidence-based fitness, nutrition, and health information from Dr. Jake Emmett, PhD, a retired Professor of Exercise Physiology with more than 30 years of teaching experience. Dr Jake Fitness Facts separates science from hype by debunking fitness myths, clarifying common misconceptions, and explaining what peer-reviewed research says about exercise, weight loss, fat loss, metabolism, muscle growth, strength training, cardio training, HIIT, Zone 2 cardio, protein, supplements, hydration, recovery, healthy aging, longevity, and human performance. Videos break down complex exercise science and physiology into clear, practical lessons that help viewers understand how the body works and how to apply research to real-world fitness and health decisions. No fad diets. No detox gimmicks. No influencer pseudoscience. Just science-based fitness education, myth-busting, and research-backed health information designed to help you train smarter, think critically, and make informed decisions about your health and fitness. Subscribe for evidence-based fitness facts and exercise science explained. https://www.youtube-nocookie.com/embed/c5n1X0u5e9g 115 2025-10-27T06:00:29.000Z 2026-10-22T19:54:15.476Z https://longevityharbor.com/de/watch/c5n1X0u5e9g Does Exercise Actually Reverse Prediabetes? #prediabetes #fitnessscience #diabetes https://i.ytimg.com/vi/c5n1X0u5e9g/hqdefault.jpg Prediabetes acts as a silent warning sign that you might be in greater danger than you realize. Learn how to stop the progression. Many people view prediabetes as a minor health concern, but leaving it unchecked can lead to serious issues like heart disease and nerve damage. This video breaks down the reality of your body struggling to keep up and why immediate action is necessary to protect your long-term health. We examine research, including a 2019 meta-analysis, showing that regular exercise benefits your system significantly. By combining physical activity with a plant-rich diet, you can actively lower blood sugar levels and work to prevent type 2 diabetes before it becomes a permanent diagnosis. Subscribe for weekly health and fitness breakdowns, and comment below with your biggest question about managing blood sugar levels. About the Channel: Evidence-based fitness, nutrition, and health information from Dr. Jake Emmett, PhD, a retired Professor of Exercise Physiology with more than 30 years of teaching experience. Dr Jake Fitness Facts separates science from hype by debunking fitness myths, clarifying common misconceptions, and explaining what peer-reviewed research says about exercise, weight loss, fat loss, metabolism, muscle growth, strength training, cardio training, HIIT, Zone 2 cardio, protein, supplements, hydration, recovery, healthy aging, longevity, and human performance. Videos break down complex exercise science and physiology into clear, practical lessons that help viewers understand how the body works and how to apply research to real-world fitness and health decisions. No fad diets. No detox gimmicks. No influencer pseudoscience. Just science-based fitness education, myth-busting, and research-backed health information designed to help you train smarter, think critically, and make informed decisions about your health and fitness. Subscribe for evidence-based fitness facts and exercise science explained. https://www.youtube-nocookie.com/embed/c5n1X0u5e9g 115 2025-10-27T06:00:29.000Z 2026-10-22T19:54:15.476Z https://longevityharbor.com/en/watch/c6o7Z1qOXcc DNA-Methylierung + Histonmodifikation [Epigenetische Regulation von Genen] - (Biologie, Oberstufe) https://i.ytimg.com/vi/c6o7Z1qOXcc/hqdefault.jpg Was ist die DNA-Methylierung? Was ist die Histonmodifikation? Während die Aktivität von eukaryotischen Genen an der DNA über die DNA-Methylierung reguliert werden kann, spielt bei der Modifikation an Histonen vor allem die Methylierung und Acetylierung eine wichtige Rolle. Zudem soll ein kurzer Überblick darüber gegeben werden, was die Epigenetik von der klassischen Genetik unterscheidet. https://www.youtube-nocookie.com/embed/c6o7Z1qOXcc 394 2020-04-03T12:22:09.000Z 2026-10-22T17:11:30.656Z https://longevityharbor.com/de/watch/c6o7Z1qOXcc DNA-Methylierung + Histonmodifikation [Epigenetische Regulation von Genen] - (Biologie, Oberstufe) https://i.ytimg.com/vi/c6o7Z1qOXcc/hqdefault.jpg Was ist die DNA-Methylierung? Was ist die Histonmodifikation? Während die Aktivität von eukaryotischen Genen an der DNA über die DNA-Methylierung reguliert werden kann, spielt bei der Modifikation an Histonen vor allem die Methylierung und Acetylierung eine wichtige Rolle. Zudem soll ein kurzer Überblick darüber gegeben werden, was die Epigenetik von der klassischen Genetik unterscheidet. https://www.youtube-nocookie.com/embed/c6o7Z1qOXcc 394 2020-04-03T12:22:09.000Z 2026-10-22T17:11:30.656Z https://longevityharbor.com/en/watch/c7rGiVqWhkI DOC 2025 Video: Dr. Valter Longo On Fasting Your Way To Longevity https://i.ytimg.com/vi/c7rGiVqWhkI/hqdefault.jpg Reducing your caloric intake for a period of time — typically a five day stretch every few months — is the single best intervention for extending longevity and fighting disease. So says Dr. Valter Longo, the Edna M. Jones Professor of Gerontology and Biological Sciences and the Director of the Longevity Institute at the University of Southern California-Leonard David School of Gerontology. https://www.youtube-nocookie.com/embed/c7rGiVqWhkI 608 2025-11-18T02:01:36.000Z 2026-10-22T17:43:38.468Z https://longevityharbor.com/de/watch/c7rGiVqWhkI DOC 2025 Video: Dr. Valter Longo On Fasting Your Way To Longevity https://i.ytimg.com/vi/c7rGiVqWhkI/hqdefault.jpg Reducing your caloric intake for a period of time — typically a five day stretch every few months — is the single best intervention for extending longevity and fighting disease. So says Dr. Valter Longo, the Edna M. Jones Professor of Gerontology and Biological Sciences and the Director of the Longevity Institute at the University of Southern California-Leonard David School of Gerontology. https://www.youtube-nocookie.com/embed/c7rGiVqWhkI 608 2025-11-18T02:01:36.000Z 2026-10-22T17:43:38.468Z https://longevityharbor.com/en/watch/c89Cx2spTC0 Muscle loss with age: why strength is framed as future independence https://i.ytimg.com/vi/c89Cx2spTC0/hqdefault.jpg The creator argues that muscle is more than a movement organ and that strength and function matter for ageing, not muscle mass alone. The description names insulin sensitivity, myokines and bone, brain and immune links, and says walking, gardening or yoga alone are not targeted strength training. https://www.youtube-nocookie.com/embed/c89Cx2spTC0 1270 2026-10-07T15:45:38.000Z 2026-10-22T21:03:38.955Z https://longevityharbor.com/de/watch/c89Cx2spTC0 Muskelverlust im Alter: Warum Kraft als Zukunftsvorsorge für Selbstständigkeit gilt https://i.ytimg.com/vi/c89Cx2spTC0/hqdefault.jpg Der Ersteller argumentiert, dass Muskeln mehr als ein Bewegungsorgan sind und dass Kraft und Funktion für das Altern zählen, nicht nur Muskelmasse. Die Beschreibung nennt Insulinsensitivität, Myokine sowie Verbindungen zu Knochen, Gehirn und Immunsystem und sagt, Gehen, Gartenarbeit oder Yoga allein seien kein gezieltes Krafttraining. https://www.youtube-nocookie.com/embed/c89Cx2spTC0 1270 2026-10-07T15:45:38.000Z 2026-10-22T21:03:38.955Z https://longevityharbor.com/en/watch/c8zAic2bMwk Video description: senescent cells, senolytics and senomorphics explained https://i.ytimg.com/vi/c8zAic2bMwk/hqdefault.jpg The description says the video explains how senescent cells affect aging and compares senolytic and senomorphic approaches, including a hit-and-run protocol and progress tracking. It is a promotional description; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/c8zAic2bMwk 664 2026-08-06T15:31:42.000Z 2026-10-22T23:13:43.197Z https://longevityharbor.com/de/watch/c8zAic2bMwk Videobeschreibung: seneszente Zellen, Senolytika und Senomorphika erklärt https://i.ytimg.com/vi/c8zAic2bMwk/hqdefault.jpg Laut Beschreibung erklärt das Video, wie seneszente Zellen das Altern beeinflussen, und vergleicht senolytische und senomorphe Ansätze, einschließlich eines Hit-and-Run-Protokolls und der Fortschrittskontrolle. Es ist eine werbliche Beschreibung; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/c8zAic2bMwk 664 2026-08-06T15:31:42.000Z 2026-10-22T23:13:43.197Z https://longevityharbor.com/en/watch/cA6JPeOcvEA Doctors' podcast description: creatine, longevity and Bryan Johnson's protocol https://i.ytimg.com/vi/cA6JPeOcvEA/hqdefault.jpg The description says two board-certified doctors discuss creatine evidence for muscle, brain and aging, and review Bryan Johnson's longevity protocol, separating research from hype. https://www.youtube-nocookie.com/embed/cA6JPeOcvEA 3215 2026-07-09T18:23:55.000Z 2026-10-22T23:39:09.342Z https://longevityharbor.com/de/watch/cA6JPeOcvEA Podcast-Beschreibung von Ärzten: Kreatin, Langlebigkeit und Bryan Johnsons Protokoll https://i.ytimg.com/vi/cA6JPeOcvEA/hqdefault.jpg Laut Beschreibung besprechen zwei Fachärzte die Kreatin-Evidenz für Muskeln, Gehirn und Altern und prüfen Bryan Johnsons Langlebigkeitsprotokoll, um Forschung von Hype zu trennen. https://www.youtube-nocookie.com/embed/cA6JPeOcvEA 3215 2026-07-09T18:23:55.000Z 2026-10-22T23:39:09.342Z https://longevityharbor.com/en/watch/cAXJVML6_kI Video description: Base State Longevity founder on cellular aging, vitamin E and senolytics https://i.ytimg.com/vi/cAXJVML6_kI/hqdefault.jpg According to the description, Dr. Sealy Hambright, Scientific Director and Co-Founder of Base State Longevity, discusses cellular aging processes, vitamin E, regenerative medicine and senolytics, and describes the company's approach of testing, tracking and repeating within personalized programs. https://www.youtube-nocookie.com/embed/cAXJVML6_kI 2374 2026-02-25T11:47:35.000Z 2026-10-23T02:20:15.110Z https://longevityharbor.com/de/watch/cAXJVML6_kI Videobeschreibung: Base-State-Longevity-Gründerin über Zellalterung, Vitamin E und Senolytika https://i.ytimg.com/vi/cAXJVML6_kI/hqdefault.jpg Laut Beschreibung spricht Dr. Sealy Hambright, Scientific Director und Mitgründerin von Base State Longevity, über zelluläre Alterungsprozesse, Vitamin E, regenerative Medizin und Senolytika und beschreibt den Ansatz des Unternehmens mit Testen, Verfolgen und Wiederholen in personalisierten Programmen. https://www.youtube-nocookie.com/embed/cAXJVML6_kI 2374 2026-02-25T11:47:35.000Z 2026-10-23T02:20:15.110Z https://longevityharbor.com/en/watch/cAZBi7W8snw NAD+ and NMN Explained: The Science of Aging & How to Reverse It https://i.ytimg.com/vi/cAZBi7W8snw/hqdefault.jpg Is NAD+ the secret to reversing aging? Can NMN really boost energy, brain function, and longevity? In this video, we break down the science behind NAD+ and NMN, how they work in the body, and whether they truly live up to the hype. 💡 What You’ll Learn in This Video: - What is NAD+ and why is it essential for cellular health? - How NMN helps boost NAD+ levels naturally - The role of NAD+ in energy production, brain health, and anti-aging - Are NAD+ and NMN supplements worth it? What the research says - How to naturally boost NAD+ for long-term wellness Is NAD+ the future of longevity? Find out how these powerful molecules are changing the way we think about aging and vitality. Book a Consultation with Halo Wellness & Aesthetics: https://halowellnessandaesthetics.com/contact/ Follow Us: IG @halointegrativewellness | FB @halowellnessandaesthetics Like & Subscribe for more science-backed wellness and aesthetics content! #NAD #NMN #AntiAging #Longevity #HaloWellness #RegenerativeMedicine https://www.youtube-nocookie.com/embed/cAZBi7W8snw 300 2025-03-10T14:19:46.000Z 2026-10-23T00:20:28.190Z https://longevityharbor.com/de/watch/cAZBi7W8snw NAD+ and NMN Explained: The Science of Aging & How to Reverse It https://i.ytimg.com/vi/cAZBi7W8snw/hqdefault.jpg Is NAD+ the secret to reversing aging? Can NMN really boost energy, brain function, and longevity? In this video, we break down the science behind NAD+ and NMN, how they work in the body, and whether they truly live up to the hype. 💡 What You’ll Learn in This Video: - What is NAD+ and why is it essential for cellular health? - How NMN helps boost NAD+ levels naturally - The role of NAD+ in energy production, brain health, and anti-aging - Are NAD+ and NMN supplements worth it? What the research says - How to naturally boost NAD+ for long-term wellness Is NAD+ the future of longevity? Find out how these powerful molecules are changing the way we think about aging and vitality. Book a Consultation with Halo Wellness & Aesthetics: https://halowellnessandaesthetics.com/contact/ Follow Us: IG @halointegrativewellness | FB @halowellnessandaesthetics Like & Subscribe for more science-backed wellness and aesthetics content! #NAD #NMN #AntiAging #Longevity #HaloWellness #RegenerativeMedicine https://www.youtube-nocookie.com/embed/cAZBi7W8snw 300 2025-03-10T14:19:46.000Z 2026-10-23T00:20:28.190Z https://longevityharbor.com/en/watch/cAl8peRogZI The Mitochondrial Genome as a Hard Limit to Mammalian Lifespan https://i.ytimg.com/vi/cAl8peRogZI/hqdefault.jpg The link to the original article: https://www.biorxiv.org/content/10.1101/2025.06.03.656903v1.full.pdf Key-words: IGF-1 signaling, longevity, lifespan, mitochondrial genome, mtDNA, aging, hallmarks of aging, mitochondrial mutator mice, genomic instability, mitochondrial dysfunction, nutrient sensing, mitochondrial mutagenesis, sarcopenia, neurodegeneration, heart failure, cardiovascular disease, oxidative stress, PolgA D257A, DNA Polymerase , cardiomyopathy, Pappa, Pappalysin 1, proteostasis, DNA repair, telomere maintenance, splenomegaly, anemia, inflammation, cytokines, grip strength, endurance, cardiac hypertrophy, echocardiography, duplex sequencing, clonal expansion, homoplasmy, COX/SDH activity, transcriptomic profiling, metabolic flexibility, gluconeogenesis, adipokines, mTOR signaling, epigenetic, chromatin, heat shock proteins, lipid metabolism, healthspan, geroprotective, IGFBP-4, catabolic metabolism https://www.youtube-nocookie.com/embed/cAl8peRogZI 917 2025-09-16T12:07:02.000Z 2026-10-22T19:32:36.455Z https://longevityharbor.com/de/watch/cAl8peRogZI The Mitochondrial Genome as a Hard Limit to Mammalian Lifespan https://i.ytimg.com/vi/cAl8peRogZI/hqdefault.jpg The link to the original article: https://www.biorxiv.org/content/10.1101/2025.06.03.656903v1.full.pdf Key-words: IGF-1 signaling, longevity, lifespan, mitochondrial genome, mtDNA, aging, hallmarks of aging, mitochondrial mutator mice, genomic instability, mitochondrial dysfunction, nutrient sensing, mitochondrial mutagenesis, sarcopenia, neurodegeneration, heart failure, cardiovascular disease, oxidative stress, PolgA D257A, DNA Polymerase , cardiomyopathy, Pappa, Pappalysin 1, proteostasis, DNA repair, telomere maintenance, splenomegaly, anemia, inflammation, cytokines, grip strength, endurance, cardiac hypertrophy, echocardiography, duplex sequencing, clonal expansion, homoplasmy, COX/SDH activity, transcriptomic profiling, metabolic flexibility, gluconeogenesis, adipokines, mTOR signaling, epigenetic, chromatin, heat shock proteins, lipid metabolism, healthspan, geroprotective, IGFBP-4, catabolic metabolism https://www.youtube-nocookie.com/embed/cAl8peRogZI 917 2025-09-16T12:07:02.000Z 2026-10-22T19:32:36.455Z https://longevityharbor.com/en/watch/cEZE3dzSKNo NMN Breakthrough: Longer Life, Strength, and Smarter #shorts https://i.ytimg.com/vi/cEZE3dzSKNo/hqdefault.jpg Fascinating study reveals NMN's potential! Mice lived 30% longer. Now, a secret Special Forces study on MIB626 shows massive increases in human endurance, strength, and cognitive ability, even in conditioned individuals. #NMN #Longevity #Health #Performance #Biohacking https://www.youtube-nocookie.com/embed/cEZE3dzSKNo 115 2026-02-23T20:56:22.000Z 2026-10-22T20:11:48.172Z https://longevityharbor.com/de/watch/cEZE3dzSKNo NMN Breakthrough: Longer Life, Strength, and Smarter #shorts https://i.ytimg.com/vi/cEZE3dzSKNo/hqdefault.jpg Fascinating study reveals NMN's potential! Mice lived 30% longer. Now, a secret Special Forces study on MIB626 shows massive increases in human endurance, strength, and cognitive ability, even in conditioned individuals. #NMN #Longevity #Health #Performance #Biohacking https://www.youtube-nocookie.com/embed/cEZE3dzSKNo 115 2026-02-23T20:56:22.000Z 2026-10-22T20:11:48.172Z https://longevityharbor.com/en/watch/cFF5i4U92b4 #05 | The Truth About Anti-Aging Pills | NMN | Resveratrol | Spermidine | Dr Kiat https://i.ytimg.com/vi/cFF5i4U92b4/hqdefault.jpg Anti-aging pills are promoted as if they were the fountain of youth in a capsule. But when we look beyond the marketing, the scientific evidence tells a more cautious story. In this episode, Dr. Kiat examines three of the most hyped anti-aging supplements - NMN, Resveratrol, and Spermidine. While early laboratory studies may sound promising, long-term human data is lacking. We also explore why most anti-aging supplements fail to live up to expectations, and the key principles that should guide how we evaluate any supplement - from evidence quality and purity to clinical safety. Healthy aging is not about chasing miracle pills. It is about building a foundation on proven strategies. Supplements may play a supporting role, but they should never replace the fundamentals. In this video you will learn: 00:00 - Anti-Aging Pills, Hype vs Truth 00:35 - NMN 02:58 - Resveratrol 04:23 - Spermidine 05:24 - Why Most Anti-Aging Pills Fail 07:26 - How I Judge a Supplement 08:05 - Final Takeaway: Lifestyle Over Pills 🔔 Subscribe to stay informed with medical facts that matter - from one of the world’s top 1% most cited cardiologists. Disclaimer The information provided on this channel is for general educational purposes only. It is not intended as medical advice and should not be relied upon as a substitute for consultation with a qualified healthcare professional who can assess your individual health needs. Dr Hosen Kiat is an AHPRA-registered Specialist Physician in Cardiology and Nuclear Medicine (Australia). Views expressed in these videos are based on current evidence and clinical experience but may not apply to every individual. Always seek the guidance of your doctor or another qualified health provider before starting, changing, or stopping any medical treatment, exercise, or nutritional program. Never delay seeking medical advice because of something you have seen or heard on this channel. No patient–doctor relationship is created through viewing, commenting on, or subscribing to this channel. #drkiat #supple https://www.youtube-nocookie.com/embed/cFF5i4U92b4 519 2025-08-28T04:44:32.000Z 2026-10-22T18:43:11.807Z https://longevityharbor.com/de/watch/cFF5i4U92b4 #05 | The Truth About Anti-Aging Pills | NMN | Resveratrol | Spermidine | Dr Kiat https://i.ytimg.com/vi/cFF5i4U92b4/hqdefault.jpg Anti-aging pills are promoted as if they were the fountain of youth in a capsule. But when we look beyond the marketing, the scientific evidence tells a more cautious story. In this episode, Dr. Kiat examines three of the most hyped anti-aging supplements - NMN, Resveratrol, and Spermidine. While early laboratory studies may sound promising, long-term human data is lacking. We also explore why most anti-aging supplements fail to live up to expectations, and the key principles that should guide how we evaluate any supplement - from evidence quality and purity to clinical safety. Healthy aging is not about chasing miracle pills. It is about building a foundation on proven strategies. Supplements may play a supporting role, but they should never replace the fundamentals. In this video you will learn: 00:00 - Anti-Aging Pills, Hype vs Truth 00:35 - NMN 02:58 - Resveratrol 04:23 - Spermidine 05:24 - Why Most Anti-Aging Pills Fail 07:26 - How I Judge a Supplement 08:05 - Final Takeaway: Lifestyle Over Pills 🔔 Subscribe to stay informed with medical facts that matter - from one of the world’s top 1% most cited cardiologists. Disclaimer The information provided on this channel is for general educational purposes only. It is not intended as medical advice and should not be relied upon as a substitute for consultation with a qualified healthcare professional who can assess your individual health needs. Dr Hosen Kiat is an AHPRA-registered Specialist Physician in Cardiology and Nuclear Medicine (Australia). Views expressed in these videos are based on current evidence and clinical experience but may not apply to every individual. Always seek the guidance of your doctor or another qualified health provider before starting, changing, or stopping any medical treatment, exercise, or nutritional program. Never delay seeking medical advice because of something you have seen or heard on this channel. No patient–doctor relationship is created through viewing, commenting on, or subscribing to this channel. #drkiat #supple https://www.youtube-nocookie.com/embed/cFF5i4U92b4 519 2025-08-28T04:44:32.000Z 2026-10-22T18:43:11.807Z https://longevityharbor.com/en/watch/cLHTMFg8aWE Look younger, live longer with Dr. Michael Aziz https://i.ytimg.com/vi/cLHTMFg8aWE/hqdefault.jpg Look Younger, Live Longer with Dr. Michael Aziz Today, we're delving into the intriguing world of anti-aging with our esteemed guest, Dr. Michael Aziz, as we explore his groundbreaking book, The Ageless Revolution: 10 Hallmarks of Aging that Hold the Secret to Defeating Disease, Reversing Age, Looking Younger, and Living Longer. Dr. Aziz brings an innovative perspective to understanding aging as a treatable disease, focusing on the cellular level. In this engaging discussion, we'll learn about the hallmarks of aging and how lifestyle changes can play a crucial role in promoting longevity. From the importance of gut health to the power of reducing inflammation, Dr. Aziz provides practical, actionable advice to help us all look and feel our best no matter our age. So, if you're ready to unlock the secrets to a healthier, fitter, and more energetic you, stay tuned for this interesting conversation on the 40+ Fitness Podcast! Timestamps: 00:00 "Ageless Revolution: Defeating Aging" 04:55 "Introducing Dr. Michael Aziz" 09:47 "Basics Before Cryotherapy" 12:06 Understanding the Hallmarks of Aging 14:03 "Impact of Diet on Gut Health" 20:14 Inflammaging: Aging Cells Cause Disruption 21:11 "Skipping Meals for Cell Renewal" 24:51 "Sleep: Key to Aging Well" 29:38 Treat Aging as a Disease 31:20 "Accessible Health Improvement Guide" Get the book: The Ageless Revolution: 10 Hallmarks of Aging that Hold the Secret to Defeating Disease, Reversing Age, Looking Younger, and Living Longer - https://amzn.to/42NRU4x. https://michaelazizmd.com https://40plusfitness.com https://www.youtube-nocookie.com/embed/cLHTMFg8aWE 1985 2025-02-09T17:25:53.000Z 2026-10-22T19:32:33.206Z https://longevityharbor.com/de/watch/cLHTMFg8aWE Look younger, live longer with Dr. Michael Aziz https://i.ytimg.com/vi/cLHTMFg8aWE/hqdefault.jpg Look Younger, Live Longer with Dr. Michael Aziz Today, we're delving into the intriguing world of anti-aging with our esteemed guest, Dr. Michael Aziz, as we explore his groundbreaking book, The Ageless Revolution: 10 Hallmarks of Aging that Hold the Secret to Defeating Disease, Reversing Age, Looking Younger, and Living Longer. Dr. Aziz brings an innovative perspective to understanding aging as a treatable disease, focusing on the cellular level. In this engaging discussion, we'll learn about the hallmarks of aging and how lifestyle changes can play a crucial role in promoting longevity. From the importance of gut health to the power of reducing inflammation, Dr. Aziz provides practical, actionable advice to help us all look and feel our best no matter our age. So, if you're ready to unlock the secrets to a healthier, fitter, and more energetic you, stay tuned for this interesting conversation on the 40+ Fitness Podcast! Timestamps: 00:00 "Ageless Revolution: Defeating Aging" 04:55 "Introducing Dr. Michael Aziz" 09:47 "Basics Before Cryotherapy" 12:06 Understanding the Hallmarks of Aging 14:03 "Impact of Diet on Gut Health" 20:14 Inflammaging: Aging Cells Cause Disruption 21:11 "Skipping Meals for Cell Renewal" 24:51 "Sleep: Key to Aging Well" 29:38 Treat Aging as a Disease 31:20 "Accessible Health Improvement Guide" Get the book: The Ageless Revolution: 10 Hallmarks of Aging that Hold the Secret to Defeating Disease, Reversing Age, Looking Younger, and Living Longer - https://amzn.to/42NRU4x. https://michaelazizmd.com https://40plusfitness.com https://www.youtube-nocookie.com/embed/cLHTMFg8aWE 1985 2025-02-09T17:25:53.000Z 2026-10-22T19:32:33.206Z https://longevityharbor.com/en/watch/cNfLMkfDTEM Video description: six proposed habits for healthy aging after 60 https://i.ytimg.com/vi/cNfLMkfDTEM/hqdefault.jpg The description presents six everyday habits for adults over 60: movement, nutrition, sleep, brain engagement, social connection and consistency. It names no studies, numbers or outcomes. https://www.youtube-nocookie.com/embed/cNfLMkfDTEM 1421 2026-09-24T23:54:19.000Z 2026-10-22T21:51:18.819Z https://longevityharbor.com/de/watch/cNfLMkfDTEM Videobeschreibung: sechs vorgeschlagene Gewohnheiten für gesundes Altern ab 60 https://i.ytimg.com/vi/cNfLMkfDTEM/hqdefault.jpg Die Beschreibung nennt sechs Alltagsgewohnheiten für Erwachsene über 60: Bewegung, Ernährung, Schlaf, geistige Aktivität, soziale Kontakte und Beständigkeit. Studien, Zahlen oder Ergebnisse werden nicht genannt. https://www.youtube-nocookie.com/embed/cNfLMkfDTEM 1421 2026-09-24T23:54:19.000Z 2026-10-22T21:51:18.819Z https://longevityharbor.com/en/watch/cVZHwTJZ6n0 Targeting Senescent Cells? Dose and Timing Matters - with Dr. Greg Kelly https://i.ytimg.com/vi/cVZHwTJZ6n0/hqdefault.jpg Get ready for a deep dive into the world of cellular senescence and its implications for aging. Dr. Greg Kelly joins me on New Frontiers to explain the science behind targeting this Hallmark of Aging and share natural compounds and activities that target cellular senescence. I am particularly excited for you to hear his thoughts around dosing and cyclical timing of exposure to senolytic compounds, such as fisetin, luteolin, quercetin, and piperlongumine, and why that may make the difference between having the effect you want... or not. Don't miss his advice on smart exercise tweaks for aging and the caution that overdoing it with exercise in our later years is much more harmful than it was in our twenties. Lots to unpack here. Enjoy! - DrKF Head over to https://www.drkarafitzgerald.com/fxmed-podcast/ for all the full transcription and all relevant links and resources. *Guest information* Dr. Greg Kelly is Senior Director of Product Development at Neurohacker Collective, naturopathic physician (N.D.), and author of the book Shape Shift. Dr. Kelly was the editor of the journal Alternative Medicine Review and has published hundreds of articles on natural medicine and nutrition, contributed three chapters to the Textbook of Natural Medicine, and has more than 30 journal articles indexed on Pubmed. greg@neurohacker.com https://www.facebook.com/neurohackercollective https://www.instagram.com/neurohacker/ https://www.linkedin.com/in/gregory-kelly-98b96b138/ *Qualia Discount for New Frontiers Listeners* If you’re in your late 20’s or older, adding Qualia Senolytic to your diet can play a CRUCIAL role in combating negative aging symptoms. Go to https://tinyurl.com/4mst9py9 for up to 50% off Qualia Senolytic and as a listener of New Frontiers podcast use code KARA at checkout for an extra 15% off your first purchase. *Show Notes* Dr. Gregory Kelly: https://neurohacker.com/people/greg-kelly Neurohacker Collective: https://tinyurl.com/3zpsaw3s Shape Shift: https://tinyurl.com/3zpsaw3s Alternative Medicine Review: htt https://www.youtube-nocookie.com/embed/cVZHwTJZ6n0 4576 2024-03-28T17:37:12.000Z 2026-10-22T19:32:33.255Z https://longevityharbor.com/de/watch/cVZHwTJZ6n0 Targeting Senescent Cells? Dose and Timing Matters - with Dr. Greg Kelly https://i.ytimg.com/vi/cVZHwTJZ6n0/hqdefault.jpg Get ready for a deep dive into the world of cellular senescence and its implications for aging. Dr. Greg Kelly joins me on New Frontiers to explain the science behind targeting this Hallmark of Aging and share natural compounds and activities that target cellular senescence. I am particularly excited for you to hear his thoughts around dosing and cyclical timing of exposure to senolytic compounds, such as fisetin, luteolin, quercetin, and piperlongumine, and why that may make the difference between having the effect you want... or not. Don't miss his advice on smart exercise tweaks for aging and the caution that overdoing it with exercise in our later years is much more harmful than it was in our twenties. Lots to unpack here. Enjoy! - DrKF Head over to https://www.drkarafitzgerald.com/fxmed-podcast/ for all the full transcription and all relevant links and resources. *Guest information* Dr. Greg Kelly is Senior Director of Product Development at Neurohacker Collective, naturopathic physician (N.D.), and author of the book Shape Shift. Dr. Kelly was the editor of the journal Alternative Medicine Review and has published hundreds of articles on natural medicine and nutrition, contributed three chapters to the Textbook of Natural Medicine, and has more than 30 journal articles indexed on Pubmed. greg@neurohacker.com https://www.facebook.com/neurohackercollective https://www.instagram.com/neurohacker/ https://www.linkedin.com/in/gregory-kelly-98b96b138/ *Qualia Discount for New Frontiers Listeners* If you’re in your late 20’s or older, adding Qualia Senolytic to your diet can play a CRUCIAL role in combating negative aging symptoms. Go to https://tinyurl.com/4mst9py9 for up to 50% off Qualia Senolytic and as a listener of New Frontiers podcast use code KARA at checkout for an extra 15% off your first purchase. *Show Notes* Dr. Gregory Kelly: https://neurohacker.com/people/greg-kelly Neurohacker Collective: https://tinyurl.com/3zpsaw3s Shape Shift: https://tinyurl.com/3zpsaw3s Alternative Medicine Review: htt https://www.youtube-nocookie.com/embed/cVZHwTJZ6n0 4576 2024-03-28T17:37:12.000Z 2026-10-22T19:32:33.255Z https://longevityharbor.com/en/watch/cVvB-1N61e8 Epigenetic clocks: DNA methylation and estimated biological age https://i.ytimg.com/vi/cVvB-1N61e8/hqdefault.jpg The description says epigenetic clocks estimate biological age from DNA methylation patterns linked to aging; it states they do not predict exactly how long someone will live. https://www.youtube-nocookie.com/embed/cVvB-1N61e8 122 2026-05-03T17:00:44.000Z 2026-10-23T01:19:15.221Z https://longevityharbor.com/de/watch/cVvB-1N61e8 Epigenetische Uhren: DNA-Methylierung und geschätztes biologisches Alter https://i.ytimg.com/vi/cVvB-1N61e8/hqdefault.jpg Laut Beschreibung schätzen epigenetische Uhren das biologische Alter anhand von DNA-Methylierungsmustern, die mit Altern verbunden sind; sie sagen nicht genau voraus, wie lange jemand lebt. https://www.youtube-nocookie.com/embed/cVvB-1N61e8 122 2026-05-03T17:00:44.000Z 2026-10-23T01:19:15.221Z https://longevityharbor.com/en/watch/ca2VcmXAgKA Rapamycin from Easter Island soil: mTOR research and the human aging question https://i.ytimg.com/vi/ca2VcmXAgKA/hqdefault.jpg The description traces rapamycin from soil microorganisms on Easter Island to the mTOR pathway and says inhibiting mTOR extended lifespan in several laboratory organisms, including mice, while stressing that this does not establish an anti-aging drug for humans. https://www.youtube-nocookie.com/embed/ca2VcmXAgKA 324 2026-08-24T18:30:20.000Z 2026-10-22T22:47:05.304Z https://longevityharbor.com/de/watch/ca2VcmXAgKA Rapamycin aus Osterinsel-Erde: mTOR-Forschung und die Frage nach dem menschlichen Altern https://i.ytimg.com/vi/ca2VcmXAgKA/hqdefault.jpg Die Beschreibung verfolgt Rapamycin von Bodenmikroorganismen auf der Osterinsel bis zum mTOR-Signalweg und berichtet, dass die Hemmung von mTOR die Lebensspanne in mehreren Labororganismen, darunter Mäuse, verlängerte – betont aber, dass dies kein Anti-Aging-Medikament für Menschen belegt. https://www.youtube-nocookie.com/embed/ca2VcmXAgKA 324 2026-08-24T18:30:20.000Z 2026-10-22T22:47:05.304Z https://longevityharbor.com/en/watch/cba4J1a68Vs Aging is a PREVENTABLE Disease https://i.ytimg.com/vi/cba4J1a68Vs/hqdefault.jpg What is aging? What is longevity? Is aging inevitable? As I open this video I say "I would never want to be a hundred years old..." and yes, this is something I hear from lots of people who are growing older. Why is that? Two reasons...either you don't love your life or you're fearful of what being a hundred means with our current notion of aging. One hundred years of age may mean old, weak and frail, dealing with chronic disease. TAKE A DEEPER DIVE INTO AGING AND LONGEVITY Lifespan by Dr. David Sinclair - https://citizensurgeon.co/Lifespan Bluezones by Dan Buettner - https://citizensurgeon.co/Bluezones Outlive by Peter Attia - https://citizensurgeon.co/Outlive Ending Aging by Aubrey Degrey - https://citizensurgeon.co/EndingAging It doesn't have to...the field of aging and longevity is incredibly exciting and is a passion project of mine as I continue to iterate my approach to health. If you want to sign up for the CITIZENSURGEON community sign up right here!! https://citizensurgeon.co/signup In this video I'm going to introduce you to the concepts of aging and longevity. I"m going to help define aging, take a deeper look at the genome and the epigenome and why the epigenome is so important when we look at advanced age. I'm also going to explore healthspan and lifespan and show you graphically how modern medicine has effected both of these. Finally I'm going to introduce you to a paper that defines the hallmarks of aging as well as some targets we can go after to improve our healthspan and our lifespan. Jump ahead with these chapter links! Start 00:00 Healthspan and Lifespan 04:30 Defining Aging 09:55 Epigenome explained 13:12 Hallmarks of Aging 17:00 Targets of Aging 20:24 WHO AM I? I'm Dr. Erik Pearson, FACS and I am a board certified pediatric surgeon living in Las Vegas. I make surgical education videos on all topics in general surgery, health, longevity as well as talks on lifestyle design as a surgeon, book reviews, and studying effectively. I also write a substack exploring the d https://www.youtube-nocookie.com/embed/cba4J1a68Vs 1391 2024-11-02T14:00:45.000Z 2026-10-22T17:43:39.307Z https://longevityharbor.com/de/watch/cba4J1a68Vs Aging is a PREVENTABLE Disease https://i.ytimg.com/vi/cba4J1a68Vs/hqdefault.jpg What is aging? What is longevity? Is aging inevitable? As I open this video I say "I would never want to be a hundred years old..." and yes, this is something I hear from lots of people who are growing older. Why is that? Two reasons...either you don't love your life or you're fearful of what being a hundred means with our current notion of aging. One hundred years of age may mean old, weak and frail, dealing with chronic disease. TAKE A DEEPER DIVE INTO AGING AND LONGEVITY Lifespan by Dr. David Sinclair - https://citizensurgeon.co/Lifespan Bluezones by Dan Buettner - https://citizensurgeon.co/Bluezones Outlive by Peter Attia - https://citizensurgeon.co/Outlive Ending Aging by Aubrey Degrey - https://citizensurgeon.co/EndingAging It doesn't have to...the field of aging and longevity is incredibly exciting and is a passion project of mine as I continue to iterate my approach to health. If you want to sign up for the CITIZENSURGEON community sign up right here!! https://citizensurgeon.co/signup In this video I'm going to introduce you to the concepts of aging and longevity. I"m going to help define aging, take a deeper look at the genome and the epigenome and why the epigenome is so important when we look at advanced age. I'm also going to explore healthspan and lifespan and show you graphically how modern medicine has effected both of these. Finally I'm going to introduce you to a paper that defines the hallmarks of aging as well as some targets we can go after to improve our healthspan and our lifespan. Jump ahead with these chapter links! Start 00:00 Healthspan and Lifespan 04:30 Defining Aging 09:55 Epigenome explained 13:12 Hallmarks of Aging 17:00 Targets of Aging 20:24 WHO AM I? I'm Dr. Erik Pearson, FACS and I am a board certified pediatric surgeon living in Las Vegas. I make surgical education videos on all topics in general surgery, health, longevity as well as talks on lifestyle design as a surgeon, book reviews, and studying effectively. I also write a substack exploring the d https://www.youtube-nocookie.com/embed/cba4J1a68Vs 1391 2024-11-02T14:00:45.000Z 2026-10-22T17:43:39.307Z https://longevityharbor.com/en/watch/cekFZNEjX-Y Video description: weekly rapamycin protocol claims for mammalian healthspan https://i.ytimg.com/vi/cekFZNEjX-Y/hqdefault.jpg The description says a prescription drug taken once weekly extends healthy lifespan in mammals by 10–20% and that longevity researchers consider timing more important than dosage; it presents a weekly rapamycin protocol and daily habits, attributed to the creator. https://www.youtube-nocookie.com/embed/cekFZNEjX-Y 209 2025-12-20T14:01:15.000Z 2026-10-23T03:14:35.435Z https://longevityharbor.com/de/watch/cekFZNEjX-Y Videobeschreibung: wöchentliches Rapamycin-Protokoll und Healthspan bei Säugetieren https://i.ytimg.com/vi/cekFZNEjX-Y/hqdefault.jpg Laut Beschreibung verlängert ein einmal wöchentlich eingenommenes verschreibungspflichtiges Medikament die gesunde Lebensspanne bei Säugetieren um 10–20 %, und Langlebigkeitsforschende halten den Zeitpunkt für wichtiger als die Dosis; vorgestellt werden ein wöchentliches Rapamycin-Protokoll und tägliche Gewohnheiten, laut Ersteller. https://www.youtube-nocookie.com/embed/cekFZNEjX-Y 209 2025-12-20T14:01:15.000Z 2026-10-23T03:14:35.435Z https://longevityharbor.com/en/watch/chnxUa4DwMI SENIORS: Add THIS to Your Morning Water — Cancer Starves, Stem Cells Activate, Kidneys Reset https://i.ytimg.com/vi/chnxUa4DwMI/hqdefault.jpg Repair Your Cells in 30 Days 👉 https://doctorbecker.netlify.app 😴 Exhausted by 2PM? Brain fog? Weight won't budge? ⬇️ 2.6M+ viewed this protocol — now it's yours: 🔬 https://doctorbecker.netlify.app 30 days. 7 foods. No pills. No gym. Backed by 28 studies. --- ⚠️ MEDICAL EDUCATION DISCLAIMER This video provides educational information about systemic pH modulation, magnesium supplementation, and renal protection through dietary compounds. All recommendations are based on peer-reviewed research and clinical experience, but should not replace personalized medical advice. Always consult your healthcare provider before making changes to your health regimen, especially if you have existing conditions or take medications. Individual results may vary. This content is intended for adults 50+ interested in evidence-based health information. Most people over 60 wake up in a state of hidden physiological stress — and don't know it. Three compounds costing pennies a day may change how your kidneys age, how your cells repair overnight, and how your body handles the acid load it's been silently accumulating for decades. 🔴 Key Topics Covered: - Why overnight dehydration amplifies cortisol and accelerates morning inflammation - How magnesium fuels the AMPK-driven cellular cleanup window before breakfast - The clinical evidence behind citrate and bicarbonate for kidney protection and pH modulation - The Warburg Effect: why tumor microenvironments become acidic — and what the research says about alkalizing agents - The exact morning protocol: doses, timing, forms, and who should modify it first Could the most powerful anti-aging ritual you're missing take less than 5 minutes and cost under $1 a day? 📚 RESEARCH CITED IN THIS VIDEO: Primary Studies: - Journal of Applied Physiology (2025). Low hydration linked to significantly greater cortisol reactivity under standardized stress conditions. - Cell Regeneration systematic review (April 2025). Autophagy shown to be indispensable for adult stem cell homeostasis; its decl https://www.youtube-nocookie.com/embed/chnxUa4DwMI 2347 2026-03-11T19:00:00.000Z 2026-10-22T19:54:19.495Z https://longevityharbor.com/de/watch/chnxUa4DwMI SENIORS: Add THIS to Your Morning Water — Cancer Starves, Stem Cells Activate, Kidneys Reset https://i.ytimg.com/vi/chnxUa4DwMI/hqdefault.jpg Repair Your Cells in 30 Days 👉 https://doctorbecker.netlify.app 😴 Exhausted by 2PM? Brain fog? Weight won't budge? ⬇️ 2.6M+ viewed this protocol — now it's yours: 🔬 https://doctorbecker.netlify.app 30 days. 7 foods. No pills. No gym. Backed by 28 studies. --- ⚠️ MEDICAL EDUCATION DISCLAIMER This video provides educational information about systemic pH modulation, magnesium supplementation, and renal protection through dietary compounds. All recommendations are based on peer-reviewed research and clinical experience, but should not replace personalized medical advice. Always consult your healthcare provider before making changes to your health regimen, especially if you have existing conditions or take medications. Individual results may vary. This content is intended for adults 50+ interested in evidence-based health information. Most people over 60 wake up in a state of hidden physiological stress — and don't know it. Three compounds costing pennies a day may change how your kidneys age, how your cells repair overnight, and how your body handles the acid load it's been silently accumulating for decades. 🔴 Key Topics Covered: - Why overnight dehydration amplifies cortisol and accelerates morning inflammation - How magnesium fuels the AMPK-driven cellular cleanup window before breakfast - The clinical evidence behind citrate and bicarbonate for kidney protection and pH modulation - The Warburg Effect: why tumor microenvironments become acidic — and what the research says about alkalizing agents - The exact morning protocol: doses, timing, forms, and who should modify it first Could the most powerful anti-aging ritual you're missing take less than 5 minutes and cost under $1 a day? 📚 RESEARCH CITED IN THIS VIDEO: Primary Studies: - Journal of Applied Physiology (2025). Low hydration linked to significantly greater cortisol reactivity under standardized stress conditions. - Cell Regeneration systematic review (April 2025). Autophagy shown to be indispensable for adult stem cell homeostasis; its decl https://www.youtube-nocookie.com/embed/chnxUa4DwMI 2347 2026-03-11T19:00:00.000Z 2026-10-22T19:54:19.495Z https://longevityharbor.com/en/watch/ckA9OD-K5is Nutrition & Aging | Aging Matters | NPT Reports https://i.ytimg.com/vi/ckA9OD-K5is/hqdefault.jpg Of the diseases that can affect how we age, malnutrition is not an obvious one. However, researchers say more and more older adults are malnourished, including people who may look healthy or who may even be overweight. The documentary "Nutrition and Aging" examines the hidden epidemic of malnutrition and under-nutrition among older adults in the United States. National reports consistently show that Tennessee is among the worst states when it comes to percentage of adults age 60 and older who face the threat of hunger or lack access to quality food, what is known as “food insecurity.” Aging presents other challenges to maintaining a balanced diet, including changes to how bodies process foods and nutrients, how our digestive system works, and how foods taste. Some older people develop difficulty swallowing; others are not able to shop for or prepare meals, while others find the cost of groceries to be a deterrent. The result of these numerous factors is that one in four older adults has some form of malnutrition. Learn more at: https://goo.gl/6iNMfV https://www.youtube-nocookie.com/embed/ckA9OD-K5is 1713 2017-11-17T20:43:21.000Z 2026-10-23T01:53:57.302Z https://longevityharbor.com/de/watch/ckA9OD-K5is Nutrition & Aging | Aging Matters | NPT Reports https://i.ytimg.com/vi/ckA9OD-K5is/hqdefault.jpg Of the diseases that can affect how we age, malnutrition is not an obvious one. However, researchers say more and more older adults are malnourished, including people who may look healthy or who may even be overweight. The documentary "Nutrition and Aging" examines the hidden epidemic of malnutrition and under-nutrition among older adults in the United States. National reports consistently show that Tennessee is among the worst states when it comes to percentage of adults age 60 and older who face the threat of hunger or lack access to quality food, what is known as “food insecurity.” Aging presents other challenges to maintaining a balanced diet, including changes to how bodies process foods and nutrients, how our digestive system works, and how foods taste. Some older people develop difficulty swallowing; others are not able to shop for or prepare meals, while others find the cost of groceries to be a deterrent. The result of these numerous factors is that one in four older adults has some form of malnutrition. Learn more at: https://goo.gl/6iNMfV https://www.youtube-nocookie.com/embed/ckA9OD-K5is 1713 2017-11-17T20:43:21.000Z 2026-10-23T01:53:57.302Z https://longevityharbor.com/en/watch/cp6utdnJ_Jk Telomeres and epigenetic clocks in dogs: faster biological aging and death risk https://i.ytimg.com/vi/cp6utdnJ_Jk/hqdefault.jpg The description presents telomeres and epigenetic clocks as ways to read biological age, and reports that larger dog breeds age epigenetically faster and that faster-aging dogs had a higher death risk. https://www.youtube-nocookie.com/embed/cp6utdnJ_Jk 349 2026-08-17T04:00:22.000Z 2026-10-22T22:57:14.045Z https://longevityharbor.com/de/watch/cp6utdnJ_Jk Telomere und epigenetische Uhren bei Hunden: schnelleres biologisches Altern und Sterberisiko https://i.ytimg.com/vi/cp6utdnJ_Jk/hqdefault.jpg Die Beschreibung stellt Telomere und epigenetische Uhren als Möglichkeiten vor, biologisches Alter zu lesen, und berichtet, dass größere Hunderassen epigenetisch schneller altern und schneller alternde Hunde ein höheres Sterberisiko hatten. https://www.youtube-nocookie.com/embed/cp6utdnJ_Jk 349 2026-08-17T04:00:22.000Z 2026-10-22T22:57:14.045Z https://longevityharbor.com/en/watch/cpEL_B0twhc NMN explained: a precursor in the NAD+ pathway https://i.ytimg.com/vi/cpEL_B0twhc/hqdefault.jpg The description says NMN is a molecule the body makes and a direct precursor of NAD+; human studies reportedly show NMN raises NAD+ levels, but effects on energy, metabolism and ageing are still being studied. https://www.youtube-nocookie.com/embed/cpEL_B0twhc 176 2026-07-17T08:00:07.000Z 2026-10-22T23:30:03.504Z https://longevityharbor.com/de/watch/cpEL_B0twhc NMN erklärt: ein Vorläufer im NAD+-Weg https://i.ytimg.com/vi/cpEL_B0twhc/hqdefault.jpg Laut Beschreibung ist NMN ein körpereigenes Molekül und direkter Vorläufer von NAD+; menschliche Studien zeigen demnach, dass NMN die NAD+-Spiegel erhöht, doch Effekte auf Energie, Stoffwechsel und Altern werden noch untersucht. https://www.youtube-nocookie.com/embed/cpEL_B0twhc 176 2026-07-17T08:00:07.000Z 2026-10-22T23:30:03.504Z https://longevityharbor.com/en/watch/ctAxnTdIX-Y The Effect of Fasting on the Aging Process https://i.ytimg.com/vi/ctAxnTdIX-Y/hqdefault.jpg Curious about how fasting might influence the aging process? In this video, we explore the fascinating science behind fasting and its potential benefits for longevity. Discover how intermittent fasting, calorie restriction, and prolonged fasting can impact cellular health, reduce inflammation, and promote autophagy. We'll delve into the latest research and expert opinions to understand how fasting could help slow down aging and improve overall well-being. Join us on this insightful journey to uncover the secrets of a healthier, longer life! Don't forget to like, comment, and subscribe for more health and wellness content. https://www.youtube-nocookie.com/embed/ctAxnTdIX-Y 467 2024-06-24T12:00:37.000Z 2026-10-22T19:54:18.184Z https://longevityharbor.com/de/watch/ctAxnTdIX-Y The Effect of Fasting on the Aging Process https://i.ytimg.com/vi/ctAxnTdIX-Y/hqdefault.jpg Curious about how fasting might influence the aging process? In this video, we explore the fascinating science behind fasting and its potential benefits for longevity. Discover how intermittent fasting, calorie restriction, and prolonged fasting can impact cellular health, reduce inflammation, and promote autophagy. We'll delve into the latest research and expert opinions to understand how fasting could help slow down aging and improve overall well-being. Join us on this insightful journey to uncover the secrets of a healthier, longer life! Don't forget to like, comment, and subscribe for more health and wellness content. https://www.youtube-nocookie.com/embed/ctAxnTdIX-Y 467 2024-06-24T12:00:37.000Z 2026-10-22T19:54:18.184Z https://longevityharbor.com/en/watch/ctN57Gf71Tw Discoveries in fasting research with Dr. Franziska Grundler | Buchinger Wilhelmi https://i.ytimg.com/vi/ctN57Gf71Tw/hqdefault.jpg ► Fasting Developments ✔ Scientific Discoveries ✔ with Franziska Grundler 🔔 Subscribe to the official Buchinger Wilhelmi YouTube channel – the world’s leading Clinics for therapeutic fasting, integrative medicine, and inspiration ► https://bit.ly/BuchingerWilhelmiKlinik In our new video, our Scientific Project Manager, Franziska Grundler, talks about scientific discoveries and research findings by our Science Department at Buchinger Wilhelmi, in fasting and its effects on health. Watch the video to learn more. The Buchinger Wilhelmi Clinic Marbella organized this medical congress in October as part of the 50th anniversary activities in 2023. The pursuit of a long and healthy life is a universal desire. In this congress, experts dived into the fundamental non-pharmacological aspects of our lives that influence healthy longevity. ► 𝗖𝗼𝗻𝘁𝗲𝗻𝘁 𝗢𝘃𝗲𝗿𝘃𝗶𝗲𝘄: 0:00 Intro 0:25 Overview of research journey 3:28 Research findings 8:47 Mild symptoms and adverse effects of fasting 9:19 Changes while fasting 10:03 Case Study: Klapdor 11:11 Health improvement in long COVID patients 12:08 Outro ► 𝗪𝗮𝘁𝗰𝗵 𝗺𝗼𝗿𝗲 Buchinger Wilhelmi fasting videos here: https://www.youtube.com/playlist?list=PLJqYz5EidEv2o7RwW1Z-q68aReBf6voeb ► 𝗗𝗼 𝘆𝗼𝘂 𝗵𝗮𝘃𝗲 𝗮𝗻𝘆 𝗾𝘂𝗲𝘀𝘁𝗶𝗼𝗻𝘀? Feel free to post them in the comment section below. We might answer them in one of our upcoming videos. ►𝗙𝗶𝗻𝗱 𝗺𝗼𝗿𝗲 𝗽𝘂𝗯𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗳𝗿𝗼𝗺 𝗼𝘂𝗿 𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝗱𝗲𝗽𝗮𝗿𝘁𝗺𝗲𝗻𝘁 𝗵𝗲𝗿𝗲: https://www.buchinger-wilhelmi.com/en/publications-of-the-buchinger-wilhelmi-clinics/ ► 𝗛𝗮𝘃𝗲 𝘆𝗼𝘂 𝗮𝗹𝗿𝗲𝗮𝗱𝘆 𝘀𝗲𝗲𝗻 𝗼𝘂𝗿 𝗙𝗔𝗦𝗧𝗜𝗡𝗚 𝗕𝗢𝗫 𝗳𝗼𝗿 𝗵𝗼𝗺𝗲 𝘂𝘀𝗲? 𝗙𝗶𝗻𝗱 𝗼𝘂𝘁 𝗺𝗼𝗿𝗲 𝗵𝗲𝗿𝗲: https://buchinger-wilhelmi-shop.com/en/fastingbox/ 🔔 𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝘁𝗼 𝗼𝘂𝗿 𝗬𝗼𝘂𝗧𝘂𝗯𝗲 𝗰𝗵𝗮𝗻𝗻𝗲𝗹 to learn more about the Buchinger Wilhelmi fasting method, periodic fasting and fasting benefits ► https://bit.ly/BuchingerWilhelmiKlinik ✅ 𝗙𝗼𝗹𝗹𝗼𝘄 #𝗕𝘂𝗰𝗵𝗶𝗻𝗴𝗲𝗿𝗪𝗶𝗹𝗵𝗲𝗹𝗺𝗶: ► Website https://www.youtube-nocookie.com/embed/ctN57Gf71Tw 753 2024-04-19T12:01:17.000Z 2026-10-22T18:32:09.953Z https://longevityharbor.com/de/watch/ctN57Gf71Tw Discoveries in fasting research with Dr. Franziska Grundler | Buchinger Wilhelmi https://i.ytimg.com/vi/ctN57Gf71Tw/hqdefault.jpg ► Fasting Developments ✔ Scientific Discoveries ✔ with Franziska Grundler 🔔 Subscribe to the official Buchinger Wilhelmi YouTube channel – the world’s leading Clinics for therapeutic fasting, integrative medicine, and inspiration ► https://bit.ly/BuchingerWilhelmiKlinik In our new video, our Scientific Project Manager, Franziska Grundler, talks about scientific discoveries and research findings by our Science Department at Buchinger Wilhelmi, in fasting and its effects on health. Watch the video to learn more. The Buchinger Wilhelmi Clinic Marbella organized this medical congress in October as part of the 50th anniversary activities in 2023. The pursuit of a long and healthy life is a universal desire. In this congress, experts dived into the fundamental non-pharmacological aspects of our lives that influence healthy longevity. ► 𝗖𝗼𝗻𝘁𝗲𝗻𝘁 𝗢𝘃𝗲𝗿𝘃𝗶𝗲𝘄: 0:00 Intro 0:25 Overview of research journey 3:28 Research findings 8:47 Mild symptoms and adverse effects of fasting 9:19 Changes while fasting 10:03 Case Study: Klapdor 11:11 Health improvement in long COVID patients 12:08 Outro ► 𝗪𝗮𝘁𝗰𝗵 𝗺𝗼𝗿𝗲 Buchinger Wilhelmi fasting videos here: https://www.youtube.com/playlist?list=PLJqYz5EidEv2o7RwW1Z-q68aReBf6voeb ► 𝗗𝗼 𝘆𝗼𝘂 𝗵𝗮𝘃𝗲 𝗮𝗻𝘆 𝗾𝘂𝗲𝘀𝘁𝗶𝗼𝗻𝘀? Feel free to post them in the comment section below. We might answer them in one of our upcoming videos. ►𝗙𝗶𝗻𝗱 𝗺𝗼𝗿𝗲 𝗽𝘂𝗯𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗳𝗿𝗼𝗺 𝗼𝘂𝗿 𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝗱𝗲𝗽𝗮𝗿𝘁𝗺𝗲𝗻𝘁 𝗵𝗲𝗿𝗲: https://www.buchinger-wilhelmi.com/en/publications-of-the-buchinger-wilhelmi-clinics/ ► 𝗛𝗮𝘃𝗲 𝘆𝗼𝘂 𝗮𝗹𝗿𝗲𝗮𝗱𝘆 𝘀𝗲𝗲𝗻 𝗼𝘂𝗿 𝗙𝗔𝗦𝗧𝗜𝗡𝗚 𝗕𝗢𝗫 𝗳𝗼𝗿 𝗵𝗼𝗺𝗲 𝘂𝘀𝗲? 𝗙𝗶𝗻𝗱 𝗼𝘂𝘁 𝗺𝗼𝗿𝗲 𝗵𝗲𝗿𝗲: https://buchinger-wilhelmi-shop.com/en/fastingbox/ 🔔 𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝘁𝗼 𝗼𝘂𝗿 𝗬𝗼𝘂𝗧𝘂𝗯𝗲 𝗰𝗵𝗮𝗻𝗻𝗲𝗹 to learn more about the Buchinger Wilhelmi fasting method, periodic fasting and fasting benefits ► https://bit.ly/BuchingerWilhelmiKlinik ✅ 𝗙𝗼𝗹𝗹𝗼𝘄 #𝗕𝘂𝗰𝗵𝗶𝗻𝗴𝗲𝗿𝗪𝗶𝗹𝗵𝗲𝗹𝗺𝗶: ► Website https://www.youtube-nocookie.com/embed/ctN57Gf71Tw 753 2024-04-19T12:01:17.000Z 2026-10-22T18:32:09.953Z https://longevityharbor.com/en/watch/cvhgZ6OmlUQ Rapamycin & Calorie Restriction - Parallel Interventions To Counteract Muscle Aging https://i.ytimg.com/vi/cvhgZ6OmlUQ/hqdefault.jpg This study compares the mechanism by which calorie restriction and rapamycin support aging muscle and surprisingly they are different. Which the authors point out offers the possibility of additive effects. Paper for this video. Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle https://www.biorxiv.org/content/10.1101/2021.05.28.446097v1.fullihub *********************************************************************************** If you would like to support our channel, we’d love a coffee…thank you! We now have monthly subscription if you would like to support us on a regular basics https://www.buymeacoffee.com/mhealthspan Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health. Products or services mentioned in this video are not a recommendation. Disclosure: Some of the links provided are affiliate links. Although we may receive a small commission from the affiliate, the cost of the product for you will always be the same, or often discounted. Thank you for supporting our channel. AUDIO COPYRIGHT STATEMENT: Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to legal@wevideo.com. In an earlier video I mentioned that we got our DNA tested We used a company called Circle based in HK but serve worldwide, which has given our listeners a 30% DISCOUNT through the above link. BIOLOGICAL AGE TEST 10% OFF: Link outside of North America Link for Canada Link for the US Discount coupon code is modernhealthspan Expiration date is April 30, 2022. NOTE: The coupon cannot be used in conjunction with any other coupons and https://www.youtube-nocookie.com/embed/cvhgZ6OmlUQ 375 2021-06-11T15:33:03.000Z 2026-10-22T17:43:41.065Z https://longevityharbor.com/de/watch/cvhgZ6OmlUQ Rapamycin & Calorie Restriction - Parallel Interventions To Counteract Muscle Aging https://i.ytimg.com/vi/cvhgZ6OmlUQ/hqdefault.jpg This study compares the mechanism by which calorie restriction and rapamycin support aging muscle and surprisingly they are different. Which the authors point out offers the possibility of additive effects. Paper for this video. Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle https://www.biorxiv.org/content/10.1101/2021.05.28.446097v1.fullihub *********************************************************************************** If you would like to support our channel, we’d love a coffee…thank you! We now have monthly subscription if you would like to support us on a regular basics https://www.buymeacoffee.com/mhealthspan Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health. Products or services mentioned in this video are not a recommendation. Disclosure: Some of the links provided are affiliate links. Although we may receive a small commission from the affiliate, the cost of the product for you will always be the same, or often discounted. Thank you for supporting our channel. AUDIO COPYRIGHT STATEMENT: Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to legal@wevideo.com. In an earlier video I mentioned that we got our DNA tested We used a company called Circle based in HK but serve worldwide, which has given our listeners a 30% DISCOUNT through the above link. BIOLOGICAL AGE TEST 10% OFF: Link outside of North America Link for Canada Link for the US Discount coupon code is modernhealthspan Expiration date is April 30, 2022. NOTE: The coupon cannot be used in conjunction with any other coupons and https://www.youtube-nocookie.com/embed/cvhgZ6OmlUQ 375 2021-06-11T15:33:03.000Z 2026-10-22T17:43:41.065Z https://longevityharbor.com/en/watch/cwmoi3CB1Zk Video description on NAD⁺, NMN/NR and aging: what the deck claims https://i.ytimg.com/vi/cwmoi3CB1Zk/hqdefault.jpg The description presents a slide deck on NAD⁺ biology, NMN and NR, citing dose-dependent blood NAD⁺ increases with NMN and biological age marker outcomes over 60 days in a multicenter randomized trial; it also states NR has FDA GRAS status. https://www.youtube-nocookie.com/embed/cwmoi3CB1Zk 442 2026-04-01T13:45:07.000Z 2026-10-23T01:49:39.613Z https://longevityharbor.com/de/watch/cwmoi3CB1Zk Videobeschreibung zu NAD⁺, NMN/NR und Altern: Was das Deck behauptet https://i.ytimg.com/vi/cwmoi3CB1Zk/hqdefault.jpg Die Beschreibung stellt ein Foliendeck zur NAD⁺-Biologie, NMN und NR vor und nennt dosisabhängige NAD⁺-Anstiege im Blut unter NMN sowie Ergebnisse zu biologischen Altersmarkern über 60 Tage in einer multizentrischen randomisierten Studie; zudem wird NR ein FDA-GRAS-Status zugeschrieben. https://www.youtube-nocookie.com/embed/cwmoi3CB1Zk 442 2026-04-01T13:45:07.000Z 2026-10-23T01:49:39.613Z https://longevityharbor.com/en/watch/czx_-DqnnrQ An introduction to the study of RAPAMYCIN | 6 - R-Files w/ Matt Kaeberlein https://i.ytimg.com/vi/czx_-DqnnrQ/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan The R-Files is a series of episodes about rapamycin, a naturally occurring compound originally discovered in soil samples from Easter Island, also known as Rapa Nui (hence the drug's name). Rapamycin belongs to a class of drugs called macrolides and has potent immunosuppressive and anti-proliferative effects. The drug has garnered attention for its potential anti-aging properties and has attracted research interest for its ability to extend lifespan and delay age-related diseases in various model organisms, including yeast and mice. In this first episode of the R-Files, Matt, who has spent a significant chunk of his career studying rapamycin, will discuss how fortuitous conversations, an appetite for unexplored territory, and an opportunity to look where others weren't looking helped him get deep into the study of rapamycin and uncover some interesting insights into how rapamycin can affect lifespan. 0:00 Trailer 1:16 The beginnings of Matt's journey into studying rapamycin 4:07 Replicative aging in yeast 7:07 SIR4 gene as a regulator of yeast replicative lifespan 13:48 Unbiased genetic screens and how they can increase the validity of results 15:55 Why people may have thought Matt was crazy 18:25 Conducting an unbiased genetic screen of yeast replicative lifespan 19:00 TOR biology in yeast and how it relates to aging 22:53 The beauty of an unbiased genetic screen 24:38 TOR signalling and nutrient sensing 25:50 Why they didn't look at rapamycin at first 27:56 Testing the effect of rapamycin on chronological lifespan in yeast 29:12 A summary of the factors that combined to lead Matt to studying rapamycin 29:55 Expanding exploration in the longevity field today Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relat https://www.youtube-nocookie.com/embed/czx_-DqnnrQ 1873 2024-02-12T15:00:37.000Z 2026-10-22T19:54:22.341Z https://longevityharbor.com/de/watch/czx_-DqnnrQ An introduction to the study of RAPAMYCIN | 6 - R-Files w/ Matt Kaeberlein https://i.ytimg.com/vi/czx_-DqnnrQ/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan The R-Files is a series of episodes about rapamycin, a naturally occurring compound originally discovered in soil samples from Easter Island, also known as Rapa Nui (hence the drug's name). Rapamycin belongs to a class of drugs called macrolides and has potent immunosuppressive and anti-proliferative effects. The drug has garnered attention for its potential anti-aging properties and has attracted research interest for its ability to extend lifespan and delay age-related diseases in various model organisms, including yeast and mice. In this first episode of the R-Files, Matt, who has spent a significant chunk of his career studying rapamycin, will discuss how fortuitous conversations, an appetite for unexplored territory, and an opportunity to look where others weren't looking helped him get deep into the study of rapamycin and uncover some interesting insights into how rapamycin can affect lifespan. 0:00 Trailer 1:16 The beginnings of Matt's journey into studying rapamycin 4:07 Replicative aging in yeast 7:07 SIR4 gene as a regulator of yeast replicative lifespan 13:48 Unbiased genetic screens and how they can increase the validity of results 15:55 Why people may have thought Matt was crazy 18:25 Conducting an unbiased genetic screen of yeast replicative lifespan 19:00 TOR biology in yeast and how it relates to aging 22:53 The beauty of an unbiased genetic screen 24:38 TOR signalling and nutrient sensing 25:50 Why they didn't look at rapamycin at first 27:56 Testing the effect of rapamycin on chronological lifespan in yeast 29:12 A summary of the factors that combined to lead Matt to studying rapamycin 29:55 Expanding exploration in the longevity field today Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relat https://www.youtube-nocookie.com/embed/czx_-DqnnrQ 1873 2024-02-12T15:00:37.000Z 2026-10-22T19:54:22.341Z https://longevityharbor.com/en/watch/d5Ogq6Myfis Review: mTOR Signaling in Aging, from Causality to Geroprotective Interventions https://i.ytimg.com/vi/d5Ogq6Myfis/hqdefault.jpg A review published in Aging describes mTOR as a dynamic signaling hub that coordinates nutrient sensing, metabolism and stress responses in aging. In model organisms evidence supports a causal role in lifespan regulation; human data remain mostly associative. Interventions such as autophagy activation, dietary changes, physical activity and senotherapeutics partly converge on mTOR. https://www.youtube-nocookie.com/embed/d5Ogq6Myfis 121 2026-10-19T16:01:47.000Z 2026-10-22T19:50:18.350Z https://longevityharbor.com/de/watch/d5Ogq6Myfis Review: mTOR-Signalweg im Altern, von Kausalität bis zu geroprotektiven Interventionen https://i.ytimg.com/vi/d5Ogq6Myfis/hqdefault.jpg Ein in Aging veröffentlichtes Review beschreibt mTOR als dynamischen Signal-Knotenpunkt, der Nährstoffwahrnehmung, Stoffwechsel und Stressreaktionen im Altern koordiniert. In Modellorganismen stützt Evidenz eine kausale Rolle bei der Lebensspannenregulation; menschliche Daten bleiben überwiegend assoziativ. Interventionen wie Autophagie-Aktivierung, Ernährung, körperliche Aktivität und Senotherapeutika laufen teils über mTOR zusammen. https://www.youtube-nocookie.com/embed/d5Ogq6Myfis 121 2026-10-19T16:01:47.000Z 2026-10-22T19:50:18.350Z https://longevityharbor.com/en/watch/d6PyyatqJSE Valter Longo, Ph.D. on Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis https://i.ytimg.com/vi/d6PyyatqJSE/hqdefault.jpg Dr. Rhonda Patrick speaks with Dr. Valter Longo, a professor of gerontology and biological sciences and director of the longevity institute at the University of Southern California. Dr. Longo has made huge contributions to the field of aging, including the role of fasting and diet in longevity and healthspan in humans as well as metabolic fasting therapies for the treatment of human diseases. EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/valter-longo?utm_source=youtube&utm_medium=youtube&utm_campaign=longo_interview "The Longevity Diet" Book: https://amzn.to/2zvxz8n Dr. Valter Longo's faculty page: https://gero.usc.edu/faculty/longo/ ProLon FMD: http://www.prolonfmd.com/ PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=longo_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/foundmyfitness/id818198322?i=1000376052437 Spotify: https://open.spotify.com/episode/4cRrTGlKdCxlPYmXWDB7Eh?si=K9rZ6q-cTli9UAj97h9P5Q&nd=1 Full interview playlist: https://www.youtube.com/playlist?list=PLJEEAVzHu9KzgkQbe2Thh35VU-HCiId_s Clips playlist: https://www.youtube.com/playlist?list=PLrGxo-5Uw8gI9-1IStYEvNxVukKxZBlmi Chapters: 00:00:00 - Introduction 00:01:00 - fasting-mimicking diet 00:04:40 - Stem cell regeneration 00:09:26 - Inflammation and aging 00:14:28 - Fasting-mimicking diet in the hospital setting 00:18:48 - Sensitizing cancer cells to death 00:32:35 - Meal timing and frequency 00:38:38 - Inducing autophagy 00:42:01 - Autoimmune, multiple sclerosis and Crohn's disease 00:48:38 - Physiological mechanism 00:54:58 - Spermidine and resveratrol 01:00:44 - Metformin 01:03:25 - growth hormone & IGF-1 pathway 01:10:53 - Exercise In this conversation, Rhonda and Valter discuss... • The effects of prolonged fasting, which refers to 2-3 day fasting intervals in mice and 4-5 days in humans. • Dr. Longo’s work on the fasting-mimicking diet, which is 5 day restricted diet that is meant to simulate some of the https://www.youtube-nocookie.com/embed/d6PyyatqJSE 4696 2016-10-01T16:34:19.000Z 2026-10-22T17:43:37.710Z https://longevityharbor.com/de/watch/d6PyyatqJSE Valter Longo, Ph.D. on Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis https://i.ytimg.com/vi/d6PyyatqJSE/hqdefault.jpg Dr. Rhonda Patrick speaks with Dr. Valter Longo, a professor of gerontology and biological sciences and director of the longevity institute at the University of Southern California. Dr. Longo has made huge contributions to the field of aging, including the role of fasting and diet in longevity and healthspan in humans as well as metabolic fasting therapies for the treatment of human diseases. EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/valter-longo?utm_source=youtube&utm_medium=youtube&utm_campaign=longo_interview "The Longevity Diet" Book: https://amzn.to/2zvxz8n Dr. Valter Longo's faculty page: https://gero.usc.edu/faculty/longo/ ProLon FMD: http://www.prolonfmd.com/ PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=longo_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/foundmyfitness/id818198322?i=1000376052437 Spotify: https://open.spotify.com/episode/4cRrTGlKdCxlPYmXWDB7Eh?si=K9rZ6q-cTli9UAj97h9P5Q&nd=1 Full interview playlist: https://www.youtube.com/playlist?list=PLJEEAVzHu9KzgkQbe2Thh35VU-HCiId_s Clips playlist: https://www.youtube.com/playlist?list=PLrGxo-5Uw8gI9-1IStYEvNxVukKxZBlmi Chapters: 00:00:00 - Introduction 00:01:00 - fasting-mimicking diet 00:04:40 - Stem cell regeneration 00:09:26 - Inflammation and aging 00:14:28 - Fasting-mimicking diet in the hospital setting 00:18:48 - Sensitizing cancer cells to death 00:32:35 - Meal timing and frequency 00:38:38 - Inducing autophagy 00:42:01 - Autoimmune, multiple sclerosis and Crohn's disease 00:48:38 - Physiological mechanism 00:54:58 - Spermidine and resveratrol 01:00:44 - Metformin 01:03:25 - growth hormone & IGF-1 pathway 01:10:53 - Exercise In this conversation, Rhonda and Valter discuss... • The effects of prolonged fasting, which refers to 2-3 day fasting intervals in mice and 4-5 days in humans. • Dr. Longo’s work on the fasting-mimicking diet, which is 5 day restricted diet that is meant to simulate some of the https://www.youtube-nocookie.com/embed/d6PyyatqJSE 4696 2016-10-01T16:34:19.000Z 2026-10-22T17:43:37.710Z https://longevityharbor.com/en/watch/d6Yk1R-kb8E Combatting Skin Aging: The Secret to Eliminating Zombie Cells https://i.ytimg.com/vi/d6Yk1R-kb8E/hqdefault.jpg Discover how to tackle cellular senescence and inflammation that lead to skin aging. We explore innovative approaches to target and eliminate zombie cells, ensuring a healthier and rejuvenated appearance with the help of anti-inflammatory solutions. #SkinAging #CellularSenescence #HealthySkin #AntiInflammatory #Longevity #SkinHealth #YouthfulAppearance #Senolytics #SkincareScience #Rejuvenation https://www.youtube-nocookie.com/embed/d6Yk1R-kb8E 122 2025-03-09T16:57:52.000Z 2026-10-22T18:43:13.639Z https://longevityharbor.com/de/watch/d6Yk1R-kb8E Combatting Skin Aging: The Secret to Eliminating Zombie Cells https://i.ytimg.com/vi/d6Yk1R-kb8E/hqdefault.jpg Discover how to tackle cellular senescence and inflammation that lead to skin aging. We explore innovative approaches to target and eliminate zombie cells, ensuring a healthier and rejuvenated appearance with the help of anti-inflammatory solutions. #SkinAging #CellularSenescence #HealthySkin #AntiInflammatory #Longevity #SkinHealth #YouthfulAppearance #Senolytics #SkincareScience #Rejuvenation https://www.youtube-nocookie.com/embed/d6Yk1R-kb8E 122 2025-03-09T16:57:52.000Z 2026-10-22T18:43:13.639Z https://longevityharbor.com/en/watch/d7P27f7EeaE Steve Horvath at Longevity Symposium Rovinj: Epigenetic Clocks of Biological Age https://i.ytimg.com/vi/d7P27f7EeaE/hqdefault.jpg Steve Horvath is a biogerontologist, whose research lies at the intersection of several fields including epigenetic biomarkers of aging, preclinical and clinical studies, genomics, epidemiology, and comparative biology. Dr Horvath is a principal investigator at Altos Labs. He and his UCLA colleagues published the first epigenetic clock for saliva in 2011. In 2013, he published the first pan-tissue clock, also known as the Horvath clock. Recently, he presented a universal clock that applies to all mammals. The recipient of several awards, he has been on Clarivate’s annual list of the world’s most influential scientific researchers every year since 2018. https://www.youtube-nocookie.com/embed/d7P27f7EeaE 2285 2023-10-17T07:04:55.000Z 2026-10-22T17:43:35.323Z https://longevityharbor.com/de/watch/d7P27f7EeaE Steve Horvath at Longevity Symposium Rovinj: Epigenetic Clocks of Biological Age https://i.ytimg.com/vi/d7P27f7EeaE/hqdefault.jpg Steve Horvath is a biogerontologist, whose research lies at the intersection of several fields including epigenetic biomarkers of aging, preclinical and clinical studies, genomics, epidemiology, and comparative biology. Dr Horvath is a principal investigator at Altos Labs. He and his UCLA colleagues published the first epigenetic clock for saliva in 2011. In 2013, he published the first pan-tissue clock, also known as the Horvath clock. Recently, he presented a universal clock that applies to all mammals. The recipient of several awards, he has been on Clarivate’s annual list of the world’s most influential scientific researchers every year since 2018. https://www.youtube-nocookie.com/embed/d7P27f7EeaE 2285 2023-10-17T07:04:55.000Z 2026-10-22T17:43:35.323Z https://longevityharbor.com/en/watch/d9K8_o1X8i8 Longevity - Das kannst du JETZT tun, um gesund alt zu werden | Quarks https://i.ytimg.com/vi/d9K8_o1X8i8/hqdefault.jpg Wie stehen deine Chancen, 100 Jahre alt zu werden? Deine Gene bestimmen nur zu etwa 10 Prozent, ob du mal in den Club der Hundertjährigen aufgenommen wirst – viel mehr hast du selbst in der Hand. Für ein langes Leben spielen viele Faktoren eine Rolle - von der richtigen Ernährung bis zum richtigen Sport. Gerade im Alter besonders wichtig: gute soziale Kontakte und eine positive Einstellung! Erfahre, was du in jedem Lebensabschnitt tun kannst, um gesund alt zu werden. Kann Intervallfasten deine Zellen verjüngen? Wie wichtig ist guter Schlaf? Und warum leben Menschen, die Tennis spielen, besonders lang? // Unser Team Autorinnen: Janina Isabell Otto, Verena Böttcher, Katrin Krieft Kamera und Schnitt: Lukas Anhalt Grafik: Luisa Zanzani Realisation: Shajan Ramezanian Redaktion: Max Ostendorf // Kapitel 00:00 So alt wirst du laut Prognosen 00:59 Level 0 - 20: Sozialer Status 02:28 Level 20 - 40: Prävention und Sport 06:56 Level 40 - 60: Ernährung und Fasten 08:54 Level 60 - 80: Ein unerwarteter Endgegner 11:20 Level 80 - 100: Die richtige Einstellung Hier geht’s zum Quellendokument https://docs.google.com/document/d/1f2trpkUy4R7hf7LZT_PBFNBs-tqddqsC/edit Mehr zum Thema Der Schlaf deines Lebens | Quarks https://www.youtube.com/watch?v=CFEQHhU6_tQ Das passiert, wenn du aufhörst zu rauchen – nach Stunden, Tagen, Jahren | Quarks https://www.youtube.com/watch?v=HT_2QiLU_vk Was passiert, wenn du auf Alkohol verzichtest? | Quarks https://www.youtube.com/watch?v=EXKDZGYbXOg Alternsforschung: Können wir unsterblich werden? | Quarks: Dimension Ralph https://www.youtube.com/watch?v=r82o-t2s0cE --- Danke fürs Zuschauen! Hat dir das Video gefallen? Dann abonniere jetzt unseren offiziellen Quarks-Kanal auf YouTube: https://www.youtube.com/Quarks?sub_confirmation=1" Besuche auch: https://www.quarks.de Du willst nichts verpassen? Melde dich für den Quarks-Newsletter an: https://www.quarks.de/allgemein/quarks-newsletter/ #Quarks auf Instagram: https://www.instagram.com/quarks.de/ Quarks auf Twitter: https://twitter.com/ https://www.youtube-nocookie.com/embed/d9K8_o1X8i8 741 2024-06-02T07:32:00.000Z 2026-10-22T18:54:07.003Z https://longevityharbor.com/de/watch/d9K8_o1X8i8 Longevity - Das kannst du JETZT tun, um gesund alt zu werden | Quarks https://i.ytimg.com/vi/d9K8_o1X8i8/hqdefault.jpg Wie stehen deine Chancen, 100 Jahre alt zu werden? Deine Gene bestimmen nur zu etwa 10 Prozent, ob du mal in den Club der Hundertjährigen aufgenommen wirst – viel mehr hast du selbst in der Hand. Für ein langes Leben spielen viele Faktoren eine Rolle - von der richtigen Ernährung bis zum richtigen Sport. Gerade im Alter besonders wichtig: gute soziale Kontakte und eine positive Einstellung! Erfahre, was du in jedem Lebensabschnitt tun kannst, um gesund alt zu werden. Kann Intervallfasten deine Zellen verjüngen? Wie wichtig ist guter Schlaf? Und warum leben Menschen, die Tennis spielen, besonders lang? // Unser Team Autorinnen: Janina Isabell Otto, Verena Böttcher, Katrin Krieft Kamera und Schnitt: Lukas Anhalt Grafik: Luisa Zanzani Realisation: Shajan Ramezanian Redaktion: Max Ostendorf // Kapitel 00:00 So alt wirst du laut Prognosen 00:59 Level 0 - 20: Sozialer Status 02:28 Level 20 - 40: Prävention und Sport 06:56 Level 40 - 60: Ernährung und Fasten 08:54 Level 60 - 80: Ein unerwarteter Endgegner 11:20 Level 80 - 100: Die richtige Einstellung Hier geht’s zum Quellendokument https://docs.google.com/document/d/1f2trpkUy4R7hf7LZT_PBFNBs-tqddqsC/edit Mehr zum Thema Der Schlaf deines Lebens | Quarks https://www.youtube.com/watch?v=CFEQHhU6_tQ Das passiert, wenn du aufhörst zu rauchen – nach Stunden, Tagen, Jahren | Quarks https://www.youtube.com/watch?v=HT_2QiLU_vk Was passiert, wenn du auf Alkohol verzichtest? | Quarks https://www.youtube.com/watch?v=EXKDZGYbXOg Alternsforschung: Können wir unsterblich werden? | Quarks: Dimension Ralph https://www.youtube.com/watch?v=r82o-t2s0cE --- Danke fürs Zuschauen! Hat dir das Video gefallen? Dann abonniere jetzt unseren offiziellen Quarks-Kanal auf YouTube: https://www.youtube.com/Quarks?sub_confirmation=1" Besuche auch: https://www.quarks.de Du willst nichts verpassen? Melde dich für den Quarks-Newsletter an: https://www.quarks.de/allgemein/quarks-newsletter/ #Quarks auf Instagram: https://www.instagram.com/quarks.de/ Quarks auf Twitter: https://twitter.com/ https://www.youtube-nocookie.com/embed/d9K8_o1X8i8 741 2024-06-02T07:32:00.000Z 2026-10-22T18:54:07.003Z https://longevityharbor.com/en/watch/dEXBFlQOTf4 PEARL Trial: Results Review with Matt Kaeberlein and Dr. Z | AgelessRx & Lifespan.io Webinar https://i.ytimg.com/vi/dEXBFlQOTf4/hqdefault.jpg This is an AgelessRx exclusive event for our patients and PEARL trial supporters! As a patient, you will have FREE access to an AMA seminar reviewing the results from the largest and longest trial on Rapamycin for healthy aging. Our Chief Medical officer, Dr. Z, will join Aging and Rapamycin expert Dr. Matt Kaeberlein, and Oliver Medvedik, Ph.D, to review the results and answer any questions. Dr. Kaeberlein is the co-founder and CEO of Optispan Health. He was also the founding Director of the UW Healthy Aging and Longevity Research Institute, the Director of the UW Nathan Shock Center of Excellence in the Basic Biology of Aging, Former Director of the Biological Mechanisms of Healthy Aging Training Program, and founder and co-Director of the Dog Aging Project. Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been recognized by several prestigious awards, and has Fellow status in the American Association for the Advancement of Science (AAAS), the American Aging Association, and the Gerontological Society of America (GSA). Dr. Kaeberlein is currently the CEO of the American Aging Association and has served on the Board of Directors for the Federation of American Societies for Experimental Biology (FASEB), AGE, and GSA. Oliver Medvedik, Co-founder of Genspace citizen science laboratory in Brooklyn NY, earned his Ph.D. at Harvard Medical School in the Biomedical and Biological Sciences program. As part of his doctoral work he has used single-celled budding yeast as a model system to map the genetic pathways that underlie the processes of aging in more complex organisms, such as humans. Prior to arriving in Boston for his doctoral studies, he has lived most of his life in New York City. He obtained his bachelor’s degree in biology from Hunter College, City University of New York. Since graduating from Harvard, he has worked as a https://www.youtube-nocookie.com/embed/dEXBFlQOTf4 5691 2024-08-28T17:26:39.000Z 2026-10-22T18:43:08.077Z https://longevityharbor.com/de/watch/dEXBFlQOTf4 PEARL Trial: Results Review with Matt Kaeberlein and Dr. Z | AgelessRx & Lifespan.io Webinar https://i.ytimg.com/vi/dEXBFlQOTf4/hqdefault.jpg This is an AgelessRx exclusive event for our patients and PEARL trial supporters! As a patient, you will have FREE access to an AMA seminar reviewing the results from the largest and longest trial on Rapamycin for healthy aging. Our Chief Medical officer, Dr. Z, will join Aging and Rapamycin expert Dr. Matt Kaeberlein, and Oliver Medvedik, Ph.D, to review the results and answer any questions. Dr. Kaeberlein is the co-founder and CEO of Optispan Health. He was also the founding Director of the UW Healthy Aging and Longevity Research Institute, the Director of the UW Nathan Shock Center of Excellence in the Basic Biology of Aging, Former Director of the Biological Mechanisms of Healthy Aging Training Program, and founder and co-Director of the Dog Aging Project. Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been recognized by several prestigious awards, and has Fellow status in the American Association for the Advancement of Science (AAAS), the American Aging Association, and the Gerontological Society of America (GSA). Dr. Kaeberlein is currently the CEO of the American Aging Association and has served on the Board of Directors for the Federation of American Societies for Experimental Biology (FASEB), AGE, and GSA. Oliver Medvedik, Co-founder of Genspace citizen science laboratory in Brooklyn NY, earned his Ph.D. at Harvard Medical School in the Biomedical and Biological Sciences program. As part of his doctoral work he has used single-celled budding yeast as a model system to map the genetic pathways that underlie the processes of aging in more complex organisms, such as humans. Prior to arriving in Boston for his doctoral studies, he has lived most of his life in New York City. He obtained his bachelor’s degree in biology from Hunter College, City University of New York. Since graduating from Harvard, he has worked as a https://www.youtube-nocookie.com/embed/dEXBFlQOTf4 5691 2024-08-28T17:26:39.000Z 2026-10-22T18:43:08.077Z https://longevityharbor.com/en/watch/dHAz-1ECHLc Der Muskel-Check | Reportage für Kinder | Checkerin Marina https://i.ytimg.com/vi/dHAz-1ECHLc/hqdefault.jpg Schon gecheckt? Noch mehr spannende Videos findest du in der Checker Welt der ARD-Mediathek: https://1.ard.de/checkerwelt. 👍 In unserem Körper gibt es mehr als 650 Muskeln! Muskeln machen uns stark, sie halten uns fit und gesund. Checkerin Marina checkt, wie unsere Muskeln funktionieren. *Die Kommentare sind zum Schutz von Minderjährigen deaktiviert. Fragen oder Bemerkungen könnt ihr gerne an CheckeinMarina@br.de mailen. Viel Freude mit dem Video! 😉 https://www.youtube-nocookie.com/embed/dHAz-1ECHLc 1464 2023-11-13T14:00:10.000Z 2026-10-22T19:54:13.912Z https://longevityharbor.com/de/watch/dHAz-1ECHLc Der Muskel-Check | Reportage für Kinder | Checkerin Marina https://i.ytimg.com/vi/dHAz-1ECHLc/hqdefault.jpg Schon gecheckt? Noch mehr spannende Videos findest du in der Checker Welt der ARD-Mediathek: https://1.ard.de/checkerwelt. 👍 In unserem Körper gibt es mehr als 650 Muskeln! Muskeln machen uns stark, sie halten uns fit und gesund. Checkerin Marina checkt, wie unsere Muskeln funktionieren. *Die Kommentare sind zum Schutz von Minderjährigen deaktiviert. Fragen oder Bemerkungen könnt ihr gerne an CheckeinMarina@br.de mailen. Viel Freude mit dem Video! 😉 https://www.youtube-nocookie.com/embed/dHAz-1ECHLc 1464 2023-11-13T14:00:10.000Z 2026-10-22T19:54:13.912Z https://longevityharbor.com/en/watch/dHonazdsWxY Video description: biological age is not one single measure https://i.ytimg.com/vi/dHonazdsWxY/hqdefault.jpg The description says biological age is not a single measure and that different cellular clocks track aging processes; it also says damage accumulation impairs cell function and affects organs. https://www.youtube-nocookie.com/embed/dHonazdsWxY 169 2026-06-25T13:30:41.000Z 2026-10-22T23:48:36.923Z https://longevityharbor.com/de/watch/dHonazdsWxY Videobeschreibung: biologisches Alter ist kein einzelnes Maß https://i.ytimg.com/vi/dHonazdsWxY/hqdefault.jpg Die Beschreibung sagt, biologisches Alter sei kein einzelnes Maß und verschiedene zelluläre Uhren verfolgten Alterungsprozesse; außerdem beeinträchtige Schadensakkumulation die Zellfunktion und betreffe Organe. https://www.youtube-nocookie.com/embed/dHonazdsWxY 169 2026-06-25T13:30:41.000Z 2026-10-22T23:48:36.923Z https://longevityharbor.com/en/watch/dIrQ3fnCN5I The Science of Aging: Epigenetics and Other Hallmarks of Aging https://i.ytimg.com/vi/dIrQ3fnCN5I/hqdefault.jpg Presenter: Michael Corley, PhD, University of California San Diego https://www.youtube-nocookie.com/embed/dIrQ3fnCN5I 2207 2025-12-04T00:32:25.000Z 2026-10-22T17:43:40.097Z https://longevityharbor.com/de/watch/dIrQ3fnCN5I The Science of Aging: Epigenetics and Other Hallmarks of Aging https://i.ytimg.com/vi/dIrQ3fnCN5I/hqdefault.jpg Presenter: Michael Corley, PhD, University of California San Diego https://www.youtube-nocookie.com/embed/dIrQ3fnCN5I 2207 2025-12-04T00:32:25.000Z 2026-10-22T17:43:40.097Z https://longevityharbor.com/en/watch/dJ4EdhtGDQk Harvard fasting researcher discusses clinical trial evidence on meal timing and metabolism https://i.ytimg.com/vi/dJ4EdhtGDQk/hqdefault.jpg According to the video description, Harvard researcher Dr. Courtney Peterson discusses what clinical trial data says about intermittent fasting, meal timing, blood sugar, weight loss and healthy aging, and why fasting headlines can mislead. https://www.youtube-nocookie.com/embed/dJ4EdhtGDQk 5810 2026-05-13T16:00:59.000Z 2026-10-23T01:06:18.125Z https://longevityharbor.com/de/watch/dJ4EdhtGDQk Harvard-Forscherin zum Fasten bespricht klinische Studien zu Essenszeitpunkt und Stoffwechsel https://i.ytimg.com/vi/dJ4EdhtGDQk/hqdefault.jpg Laut der Videobeschreibung erläutert die Harvard-Forscherin Dr. Courtney Peterson, was klinische Studiendaten zu intermittierendem Fasten, Essenszeitpunkt, Blutzucker, Gewichtsverlust und gesundem Altern sagen – und warum Schlagzeilen zum Fasten irreführen können. https://www.youtube-nocookie.com/embed/dJ4EdhtGDQk 5810 2026-05-13T16:00:59.000Z 2026-10-23T01:06:18.125Z https://longevityharbor.com/en/watch/dJfZ7wgMXyw How Michael Hall’s TOR Discovery Reframed Longevity Science https://i.ytimg.com/vi/dJfZ7wgMXyw/hqdefault.jpg We trace how a soil-derived drug led to the discovery of mTOR, why growth control sits at the core of aging biology, and where evidence ends for humans. Michael Hall’s quiet breakthroughs explain fasting, autophagy, and rapamycin without the hype. To read more about this topic (https://www.swissinfo.ch/eng/healthcare-innovation/the-basel-researcher-whose-work-triggered-a-longevity-revolution/89102004) and for more science stories (https://www.swissinfo.ch/eng/research-frontiers/) , visit our website swisinfo.ch (https://www.swissinfo.ch/eng/health-systems/switzerland-charts-new-course-on-gender-medicine-despite-headwinds/90213951) . You can help other people to find our podcast by leaving us a five-star review. Journalist: Jessica Davis Plüss (https://www.swissinfo.ch/eng/healthcare-innovation/longevity-clinics-modern-day-snake-oil-or-the-key-to-healthy-ageing/89101132) Host: Jo Fahy (https://www.swissinfo.ch/eng/author/jo-fahy/) Audio editor/video journalist: Michele Andina (https://www.swissinfo.ch/eng/author/michele-andina/) Distribution and Marketing: Xin Zhang (https://www.linkedin.com/in/xin-zhang-70327481/) Send us Fan Mail (https://www.buzzsprout.com/910414/fan_mail/new) SWI swissinfo.ch (https://www.swissinfo.ch/eng/) is a public service media company based in Bern, Switzerland. https://www.youtube-nocookie.com/embed/dJfZ7wgMXyw 1102 2025-11-25T07:20:54.000Z 2026-10-22T19:32:36.527Z https://longevityharbor.com/de/watch/dJfZ7wgMXyw How Michael Hall’s TOR Discovery Reframed Longevity Science https://i.ytimg.com/vi/dJfZ7wgMXyw/hqdefault.jpg We trace how a soil-derived drug led to the discovery of mTOR, why growth control sits at the core of aging biology, and where evidence ends for humans. Michael Hall’s quiet breakthroughs explain fasting, autophagy, and rapamycin without the hype. To read more about this topic (https://www.swissinfo.ch/eng/healthcare-innovation/the-basel-researcher-whose-work-triggered-a-longevity-revolution/89102004) and for more science stories (https://www.swissinfo.ch/eng/research-frontiers/) , visit our website swisinfo.ch (https://www.swissinfo.ch/eng/health-systems/switzerland-charts-new-course-on-gender-medicine-despite-headwinds/90213951) . You can help other people to find our podcast by leaving us a five-star review. Journalist: Jessica Davis Plüss (https://www.swissinfo.ch/eng/healthcare-innovation/longevity-clinics-modern-day-snake-oil-or-the-key-to-healthy-ageing/89101132) Host: Jo Fahy (https://www.swissinfo.ch/eng/author/jo-fahy/) Audio editor/video journalist: Michele Andina (https://www.swissinfo.ch/eng/author/michele-andina/) Distribution and Marketing: Xin Zhang (https://www.linkedin.com/in/xin-zhang-70327481/) Send us Fan Mail (https://www.buzzsprout.com/910414/fan_mail/new) SWI swissinfo.ch (https://www.swissinfo.ch/eng/) is a public service media company based in Bern, Switzerland. https://www.youtube-nocookie.com/embed/dJfZ7wgMXyw 1102 2025-11-25T07:20:54.000Z 2026-10-22T19:32:36.527Z https://longevityharbor.com/en/watch/dJmwwpSJ1wg LMP Grand Rounds LNeidernhofer 15Nov2023 https://i.ytimg.com/vi/dJmwwpSJ1wg/hqdefault.jpg "Geroscience approaches to extend healthspan"  Laura Niedernhofer, MD, PhD Professor Biochemistry Molecular Biology and Biophysics College of Biological Sciences University of Minnesota  Minneapolis, Minnesota  Faculty Host:  Dr. Sara Hamilton Hart  Objectives:  1) Define Geroscience and the impetus behind this novel approach to managing the health of our aging population. 2) Define cellular senescence and its role as a drug target  3) Provide information about the resources provided by UMN Institute on the Biology of Aging and Metabolism to support clinical research. https://www.youtube-nocookie.com/embed/dJmwwpSJ1wg 3554 2023-11-15T17:04:44.000Z 2026-10-22T17:43:40.198Z https://longevityharbor.com/de/watch/dJmwwpSJ1wg LMP Grand Rounds LNeidernhofer 15Nov2023 https://i.ytimg.com/vi/dJmwwpSJ1wg/hqdefault.jpg "Geroscience approaches to extend healthspan"  Laura Niedernhofer, MD, PhD Professor Biochemistry Molecular Biology and Biophysics College of Biological Sciences University of Minnesota  Minneapolis, Minnesota  Faculty Host:  Dr. Sara Hamilton Hart  Objectives:  1) Define Geroscience and the impetus behind this novel approach to managing the health of our aging population. 2) Define cellular senescence and its role as a drug target  3) Provide information about the resources provided by UMN Institute on the Biology of Aging and Metabolism to support clinical research. https://www.youtube-nocookie.com/embed/dJmwwpSJ1wg 3554 2023-11-15T17:04:44.000Z 2026-10-22T17:43:40.198Z https://longevityharbor.com/en/watch/dKxJ7zDn8aE Allianz Gesundheitstalk episode 2: lifestyle, nutrition and exercise for healthy aging https://i.ytimg.com/vi/dKxJ7zDn8aE/hqdefault.jpg In this episode description, journalist Thomas Schulz discusses how nutrition, exercise, sleep, stress management and social factors relate to healthy life expectancy, with lifestyle factors said to determine up to 70–80% of healthy life years. https://www.youtube-nocookie.com/embed/dKxJ7zDn8aE 1858 2026-09-14T18:44:00.000Z 2026-10-22T22:12:04.041Z https://longevityharbor.com/de/watch/dKxJ7zDn8aE Allianz Gesundheitstalk Folge 2: Lebensstil, Ernährung und Bewegung für gesundes Altern https://i.ytimg.com/vi/dKxJ7zDn8aE/hqdefault.jpg In dieser Episodenbeschreibung ordnet Journalist Thomas Schulz ein, wie Ernährung, Bewegung, Schlaf, Stressmanagement und soziale Faktoren mit gesunder Lebenserwartung zusammenhängen; Lebensstilfaktoren sollen bis zu 70–80 % der gesunden Lebensjahre bestimmen. https://www.youtube-nocookie.com/embed/dKxJ7zDn8aE 1858 2026-09-14T18:44:00.000Z 2026-10-22T22:12:04.041Z https://longevityharbor.com/en/watch/dLLkgP-0Yno Exercise and Aging – Dr. Anne Friedlander (Stanford) https://i.ytimg.com/vi/dLLkgP-0Yno/hqdefault.jpg Physical activity is powerful medicine: it can promote health and change the trajectory of aging. Science has taught us much about the pathways of disease, the causes of aging, and the mechanisms by which exercise exerts its benefits. Now, targeted exercise strategies can slow the aging process and improve both health and fitness. The presenter, Dr. Anne Friedlander, is Adjunct Professor in Human Biology at Stanford University. She has broad research experience in the areas of enhancing human performance, physiology in extreme environments, and using physical activity to promote healthy aging. This Wonderfest online event took place on May 19, 2021, via Zoom. https://www.youtube-nocookie.com/embed/dLLkgP-0Yno 3914 2021-06-15T19:50:20.000Z 2026-10-22T17:43:36.919Z https://longevityharbor.com/de/watch/dLLkgP-0Yno Exercise and Aging – Dr. Anne Friedlander (Stanford) https://i.ytimg.com/vi/dLLkgP-0Yno/hqdefault.jpg Physical activity is powerful medicine: it can promote health and change the trajectory of aging. Science has taught us much about the pathways of disease, the causes of aging, and the mechanisms by which exercise exerts its benefits. Now, targeted exercise strategies can slow the aging process and improve both health and fitness. The presenter, Dr. Anne Friedlander, is Adjunct Professor in Human Biology at Stanford University. She has broad research experience in the areas of enhancing human performance, physiology in extreme environments, and using physical activity to promote healthy aging. This Wonderfest online event took place on May 19, 2021, via Zoom. https://www.youtube-nocookie.com/embed/dLLkgP-0Yno 3914 2021-06-15T19:50:20.000Z 2026-10-22T17:43:36.919Z https://longevityharbor.com/en/watch/dLdSXu_DLxo Video description: DEAF1, muscle cleanup and exercise in aging muscle https://i.ytimg.com/vi/dLdSXu_DLxo/hqdefault.jpg A video description says a newly identified gene called DEAF1 may disrupt muscle cleanup with age, that exercise may help restore balance, and that results may differ between people. It mentions animal research and possible future therapies, but gives no numbers or study details. https://www.youtube-nocookie.com/embed/dLdSXu_DLxo 343 2026-10-19T14:01:05.000Z 2026-10-22T19:23:08.085Z https://longevityharbor.com/de/watch/dLdSXu_DLxo Videobeschreibung: DEAF1, Muskelreinigung und Bewegung in alternder Muskulatur https://i.ytimg.com/vi/dLdSXu_DLxo/hqdefault.jpg Eine Videobeschreibung sagt, ein neu identifiziertes Gen namens DEAF1 könne die Muskelreinigung mit dem Alter stören, Bewegung könne das Gleichgewicht wiederherstellen, und Ergebnisse könnten sich zwischen Menschen unterscheiden. Sie nennt Tierforschung und mögliche künftige Therapien, aber keine Zahlen oder Studiendetails. https://www.youtube-nocookie.com/embed/dLdSXu_DLxo 343 2026-10-19T14:01:05.000Z 2026-10-22T19:23:08.085Z https://longevityharbor.com/en/watch/dOMCsYGO3jA Video description: deadlift, pull-up and loaded carry for exercisers over 30 https://i.ytimg.com/vi/dOMCsYGO3jA/hqdefault.jpg The description presents three exercises — deadlift, pull-up/chin-up and loaded carry — as countering muscle, bone, hormonal and mobility changes after 30, plus a weekly programme and warm-up for the post-30 group. https://www.youtube-nocookie.com/embed/dOMCsYGO3jA 1411 2026-08-30T06:45:01.000Z 2026-10-22T22:39:23.191Z https://longevityharbor.com/de/watch/dOMCsYGO3jA Videobeschreibung: Kreuzheben, Klimmzug und Trageübung für Trainierende über 30 https://i.ytimg.com/vi/dOMCsYGO3jA/hqdefault.jpg Die Beschreibung stellt drei Übungen vor — Kreuzheben, Klimmzug und Trageübung — die Veränderungen von Muskeln, Knochen, Hormonen und Beweglichkeit nach 30 entgegenwirken sollen, dazu einen Wochenplan und ein Aufwärmprogramm für die Gruppe über 30. https://www.youtube-nocookie.com/embed/dOMCsYGO3jA 1411 2026-08-30T06:45:01.000Z 2026-10-22T22:39:23.191Z https://longevityharbor.com/en/watch/dOXAW73wB4M Fasting to Last: The Longevity Science of Skipping Meals https://i.ytimg.com/vi/dOXAW73wB4M/hqdefault.jpg 🎙️ Episode 2 — Fasting to Last: The Longevity Science of Skipping Meals Daily Longevity Rx Is skipping breakfast just a trend — or the key to living longer, stronger, and sharper? In this episode of Daily Longevity Rx, we dive deep into the science of intermittent fasting and its powerful role in reversing aging, fighting disease, and optimizing your metabolic health. From alternate-day fasting to the Fasting Mimicking Diet, we explore the latest research on how fasting affects biological age, brain performance, heart health, autophagy, and even cancer resilience. You’ll learn: • The three most common types of intermittent fasting (and which one is the most practical) • What actually happens inside your cells when you stop eating • Why ketones, BDNF, and sirtuins might be your best allies for longevity • How to leverage timing and circadian rhythm to boost health without extreme restriction • Who should be cautious — and why fasting isn’t one-size-fits-all Whether you’re curious, cautious, or already fasting, this episode will leave you with clear, science-backed takeaways you can apply today. 👉 Start small. Stay consistent. Reprogram your health. https://www.youtube-nocookie.com/embed/dOXAW73wB4M 1005 2025-06-22T20:30:05.000Z 2026-10-22T19:32:32.282Z https://longevityharbor.com/de/watch/dOXAW73wB4M Fasting to Last: The Longevity Science of Skipping Meals https://i.ytimg.com/vi/dOXAW73wB4M/hqdefault.jpg 🎙️ Episode 2 — Fasting to Last: The Longevity Science of Skipping Meals Daily Longevity Rx Is skipping breakfast just a trend — or the key to living longer, stronger, and sharper? In this episode of Daily Longevity Rx, we dive deep into the science of intermittent fasting and its powerful role in reversing aging, fighting disease, and optimizing your metabolic health. From alternate-day fasting to the Fasting Mimicking Diet, we explore the latest research on how fasting affects biological age, brain performance, heart health, autophagy, and even cancer resilience. You’ll learn: • The three most common types of intermittent fasting (and which one is the most practical) • What actually happens inside your cells when you stop eating • Why ketones, BDNF, and sirtuins might be your best allies for longevity • How to leverage timing and circadian rhythm to boost health without extreme restriction • Who should be cautious — and why fasting isn’t one-size-fits-all Whether you’re curious, cautious, or already fasting, this episode will leave you with clear, science-backed takeaways you can apply today. 👉 Start small. Stay consistent. Reprogram your health. https://www.youtube-nocookie.com/embed/dOXAW73wB4M 1005 2025-06-22T20:30:05.000Z 2026-10-22T19:32:32.282Z https://longevityharbor.com/en/watch/dPZylzjCBhs I'm 40 But My Biological Age is 23. Here's How I Did It - Chris Mirabile https://i.ytimg.com/vi/dPZylzjCBhs/hqdefault.jpg Discover your health % and get your roadmap to Top 1% Health: https://www.skool.com/top1health/ 💯💯Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Timestamps: 00:22 How Chris Started Slowing His Biological Age 05:00 What Are the Hallmarks of Aging 14:15 Targeting All Hallmarks of Aging At Once 18:15 Clinical Trials on Novos Core 27:30 Rejuvenation Olympics 36:30 Longevity Tests and Biological Age Clocks 46:29 Chris' Longevity Routine 59:35 Is Chris Getting Healthier in His 40s or Not Try Novos Longevity Supplements with code 5OFFSIIM24 for $5 OFF: https://novos.sjv.io/rQMZBy Chris Mirabile Instagram: https://www.instagram.com/slowmyage/ Longevity and Anti-Aging Playlist: https://www.youtube.com/watch?v=5KNsfEBXKMg&list=PLMaXsmhvb0r2zcztetf3oE6_zKOm9TebR&ab_channel=SiimLand Join me at the next retreat: https://aiwo.com/pages/healthacation NEW Shop: https://www.siimland.co/shop NEW Merch: https://www.siimland.com/merch Metabolic Autophagy Book: https://amzn.to/2W4YfDF Stronger by Stress Book: https://amzn.to/2VhuXTn The Mineral Fix Book: https://amzn.to/3yhey3y The Immunity Fix Book: https://amzn.to/3mssSQI Metabolic Autophagy Master Class: https://www.siimland.co/metabolic-autophagy-master-class Total Sleep Optimization Video Course: https://www.siimland.co/total-sleep-optimization-video-course Metabolic Autophagy 4 Week Meal Plan: https://www.siimland.co/offers/EwhNysUs Intermittent Fasting Video Course: https://www.siimland.co/offers/JL2Nx9Rw Check Out My Coaching: https://www.siimland.co/coaching Get Self Decode DNA Test with the code SIIM: http://get.selfdecode.com/siim Magnesium Breakthrough for a 10% Discount! https://bit.ly/3dKkd8A Use Code SIIM for 10% Off Self Decode https://bit.ly/3k4EnfQ Use Code SIIM for a 10% Discount on the KAATSU Bands https://www.kaatsu-global.com/index.cfm?Action=Store.Details&pid=11 Get Drink HRW Molecular Hydrogen for 10% OFF With the Code SIIM: https://drinkhrw.com?afmc=SIIM BON CHARGE Blue-Blocking Glasses 15% Discount with the Code SIIM: https://ww https://www.youtube-nocookie.com/embed/dPZylzjCBhs 4177 2024-05-12T13:18:28.000Z 2026-10-22T19:32:33.300Z https://longevityharbor.com/de/watch/dPZylzjCBhs I'm 40 But My Biological Age is 23. Here's How I Did It - Chris Mirabile https://i.ytimg.com/vi/dPZylzjCBhs/hqdefault.jpg Discover your health % and get your roadmap to Top 1% Health: https://www.skool.com/top1health/ 💯💯Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Timestamps: 00:22 How Chris Started Slowing His Biological Age 05:00 What Are the Hallmarks of Aging 14:15 Targeting All Hallmarks of Aging At Once 18:15 Clinical Trials on Novos Core 27:30 Rejuvenation Olympics 36:30 Longevity Tests and Biological Age Clocks 46:29 Chris' Longevity Routine 59:35 Is Chris Getting Healthier in His 40s or Not Try Novos Longevity Supplements with code 5OFFSIIM24 for $5 OFF: https://novos.sjv.io/rQMZBy Chris Mirabile Instagram: https://www.instagram.com/slowmyage/ Longevity and Anti-Aging Playlist: https://www.youtube.com/watch?v=5KNsfEBXKMg&list=PLMaXsmhvb0r2zcztetf3oE6_zKOm9TebR&ab_channel=SiimLand Join me at the next retreat: https://aiwo.com/pages/healthacation NEW Shop: https://www.siimland.co/shop NEW Merch: https://www.siimland.com/merch Metabolic Autophagy Book: https://amzn.to/2W4YfDF Stronger by Stress Book: https://amzn.to/2VhuXTn The Mineral Fix Book: https://amzn.to/3yhey3y The Immunity Fix Book: https://amzn.to/3mssSQI Metabolic Autophagy Master Class: https://www.siimland.co/metabolic-autophagy-master-class Total Sleep Optimization Video Course: https://www.siimland.co/total-sleep-optimization-video-course Metabolic Autophagy 4 Week Meal Plan: https://www.siimland.co/offers/EwhNysUs Intermittent Fasting Video Course: https://www.siimland.co/offers/JL2Nx9Rw Check Out My Coaching: https://www.siimland.co/coaching Get Self Decode DNA Test with the code SIIM: http://get.selfdecode.com/siim Magnesium Breakthrough for a 10% Discount! https://bit.ly/3dKkd8A Use Code SIIM for 10% Off Self Decode https://bit.ly/3k4EnfQ Use Code SIIM for a 10% Discount on the KAATSU Bands https://www.kaatsu-global.com/index.cfm?Action=Store.Details&pid=11 Get Drink HRW Molecular Hydrogen for 10% OFF With the Code SIIM: https://drinkhrw.com?afmc=SIIM BON CHARGE Blue-Blocking Glasses 15% Discount with the Code SIIM: https://ww https://www.youtube-nocookie.com/embed/dPZylzjCBhs 4177 2024-05-12T13:18:28.000Z 2026-10-22T19:32:33.300Z https://longevityharbor.com/en/watch/dSA-9NgIBjA Video description: body shaming at the gym and whether aesthetics outranks health https://i.ytimg.com/vi/dSA-9NgIBjA/hqdefault.jpg The description argues that aesthetic training motives are not superficial; what matters is whether motivation becomes self-determined and sustainable, while pressure from body control or constant self-evaluation can turn motivation into strain. https://www.youtube-nocookie.com/embed/dSA-9NgIBjA 180 2026-08-19T04:57:19.000Z 2026-10-22T22:56:02.735Z https://longevityharbor.com/de/watch/dSA-9NgIBjA Videobeschreibung: Bodyshaming im Fitnessstudio und ob Ästhetik vor Gesundheit steht https://i.ytimg.com/vi/dSA-9NgIBjA/hqdefault.jpg Die Beschreibung argumentiert, dass ästhetische Trainingsmotive nicht oberflächlich sind; entscheidend ist, ob die Motivation selbstbestimmt und nachhaltig wird, während Druck durch Körperkontrolle oder ständige Selbstbewertung Motivation in Belastung kippen kann. https://www.youtube-nocookie.com/embed/dSA-9NgIBjA 180 2026-08-19T04:57:19.000Z 2026-10-22T22:56:02.735Z https://longevityharbor.com/en/watch/dSXso2KbTwA Video description: 12 hallmarks of aging and where peptides are discussed https://i.ytimg.com/vi/dSXso2KbTwA/hqdefault.jpg The creator says the video explains the 12 hallmarks of aging, a framework first published in 2013 and expanded in 2023, and discusses which peptides are relevant to each pathway. She notes that immune aging is not a standalone hallmark and that she expands cellular senescence to include immune-regulating peptides. https://www.youtube-nocookie.com/embed/dSXso2KbTwA 1480 2026-01-11T14:00:58.000Z 2026-10-23T02:56:23.621Z https://longevityharbor.com/de/watch/dSXso2KbTwA Videobeschreibung: 12 Hallmarks des Alterns und wo Peptide erwähnt werden https://i.ytimg.com/vi/dSXso2KbTwA/hqdefault.jpg Die Erstellerin sagt, das Video erkläre die 12 Hallmarks des Alterns, ein 2013 erstmals veröffentlichtes und 2023 erweitertes Rahmenwerk, und bespreche, welche Peptide für jeden dieser Wege relevant sind. Sie merkt an, dass Immunaltern kein eigenständiges Hallmark ist und sie die zelluläre Seneszenz um immunregulierende Peptide erweitert. https://www.youtube-nocookie.com/embed/dSXso2KbTwA 1480 2026-01-11T14:00:58.000Z 2026-10-23T02:56:23.621Z https://longevityharbor.com/en/watch/dUMEA6QbtcU Fasting, Longevity and Cancer Care | Professor Valter Longo Explains the Science https://i.ytimg.com/vi/dUMEA6QbtcU/hqdefault.jpg Can fasting transform cancer care? Professor Valter Longo joins NCIM to explain the science of longevity, the Fasting Mimicking Diet (FMD), and integrative oncology. In this groundbreaking episode, Dr. Elizabeth Thompson sits down with Professor Valter Longo, a world-leading expert in longevity and integrative medicine. They explore the cutting-edge science of fasting, the revolutionary Fasting Mimicking Diet (FMD), and its potential to transform metabolic health, cellular repair, and longevity. Discover how fasting activates autophagy, supports stem cell regeneration, and promotes metabolic flexibility - offering a natural, evidence-based approach to sustainable wellness. Professor Longo also shares why fasting may be a powerful alternative to pharmaceutical weight-loss solutions, aligning with the body’s innate repair systems. This episode is a must-watch for health professionals, longevity enthusiasts, and anyone seeking science-backed strategies for vibrant, long-term health. Join us for a fascinating evidence-informed discussion on how lifestyle interventions may support long-term health, longevity and integrative cancer care. In this episode, you’ll learn: • Integrative medicine and longevity science • The fasting mimicking diet explained • Autophagy and cellular repair • Stem cell regeneration and metabolic health • Fasting and cancer treatment support • Fasting vs pharmaceutical approaches to weight loss • Why refeeding is essential after fasting Prof. Longo shared his expertise at our Oct 2026 Conference: Oncology Symptom Support: Advancing Care Across the Cancer Journey. For more information and to purchase a recording of the full conferences, head to: https://courses.ncim.org.uk/courses/oncology-symptom-support and use the code: podcast15 to receive 15% off the recording price. Or, do you want to learn the evidence-based fasting protocols for clinical practice? Enrol in our online self-paced course, Fasting for Longevity and Wellness, and use code PODFAST50 at checkout for a 50% https://www.youtube-nocookie.com/embed/dUMEA6QbtcU 2630 2026-03-05T09:00:51.000Z 2026-10-22T18:54:08.056Z https://longevityharbor.com/de/watch/dUMEA6QbtcU Fasting, Longevity and Cancer Care | Professor Valter Longo Explains the Science https://i.ytimg.com/vi/dUMEA6QbtcU/hqdefault.jpg Can fasting transform cancer care? Professor Valter Longo joins NCIM to explain the science of longevity, the Fasting Mimicking Diet (FMD), and integrative oncology. In this groundbreaking episode, Dr. Elizabeth Thompson sits down with Professor Valter Longo, a world-leading expert in longevity and integrative medicine. They explore the cutting-edge science of fasting, the revolutionary Fasting Mimicking Diet (FMD), and its potential to transform metabolic health, cellular repair, and longevity. Discover how fasting activates autophagy, supports stem cell regeneration, and promotes metabolic flexibility - offering a natural, evidence-based approach to sustainable wellness. Professor Longo also shares why fasting may be a powerful alternative to pharmaceutical weight-loss solutions, aligning with the body’s innate repair systems. This episode is a must-watch for health professionals, longevity enthusiasts, and anyone seeking science-backed strategies for vibrant, long-term health. Join us for a fascinating evidence-informed discussion on how lifestyle interventions may support long-term health, longevity and integrative cancer care. In this episode, you’ll learn: • Integrative medicine and longevity science • The fasting mimicking diet explained • Autophagy and cellular repair • Stem cell regeneration and metabolic health • Fasting and cancer treatment support • Fasting vs pharmaceutical approaches to weight loss • Why refeeding is essential after fasting Prof. Longo shared his expertise at our Oct 2026 Conference: Oncology Symptom Support: Advancing Care Across the Cancer Journey. For more information and to purchase a recording of the full conferences, head to: https://courses.ncim.org.uk/courses/oncology-symptom-support and use the code: podcast15 to receive 15% off the recording price. Or, do you want to learn the evidence-based fasting protocols for clinical practice? Enrol in our online self-paced course, Fasting for Longevity and Wellness, and use code PODFAST50 at checkout for a 50% https://www.youtube-nocookie.com/embed/dUMEA6QbtcU 2630 2026-03-05T09:00:51.000Z 2026-10-22T18:54:08.056Z https://longevityharbor.com/en/watch/dUX2w2g_2jQ The science behind NAD and NMN: What it means for your health and aging: Andrew Salzman, M.D. https://i.ytimg.com/vi/dUX2w2g_2jQ/hqdefault.jpg Join 1M+ subscribers on their journey towards strong and healthy: https://www.mindbodygreen.com/newsletters “ NAD is the key regulator of the entire metabolic machinery of the body,” explains Andrew Salzman, MD. Andrew Salzman, MD, physician, biomedical entrepreneur, and Chief Medical Officer at Wonderfeel, joins us to explore how optimizing NAD levels could hold the key to slowing aging, enhancing cellular function, and improving healthspan from the inside out. Plus: 0:00 What is NAD? 4:00 When does NAD decline 5:17 The connection to perimenopause & menopause 9:00 The benefits of increasing your levels 12:00 Preventing NAD from breaking down 12:45 What is CD38? 15:00 The impact of NAD on muscle mass 16:05 How to be an informed consumer of NAD supplements 17:45 Salzman’s personal routine 19:00 Dosage & beneficial ingredients in Wonderfeel products 23:15 The benefits on metabolism 24:15 Safety of NAD Referenced in the episode: - Check out Wonderfeel (https://getwonderfeel.com/?utm_source=mbg&utm_medium=podcast) - Learn more about Salzman (https://getwonderfeel.com/experts/andrew-salzman-md/?utm_source=mbg&utm_medium=podcast) - Follow Wonderfeel on Instagram (https://www.instagram.com/getwonderfeel/) - Youngr™ NMN, Wonderfeel’s NAD-boosting supplement (https://getwonderfeel.com/?utm_source=mbg&utm_medium=podcast) ABOUT mbg: mindbodygreen. One word. Here you’ll find a 360-degree approach to wellness that weaves the mental, physical, spiritual, emotional, and environmental aspects of well-being together, because we believe that these pillars of health are all interconnected. Read more here: https://www.mindbodygreen.com/​ Shop our supplements: https://shop.mindbodygreen.com/ Follow us on Social - @mindbodygreen Instagram: https://www.instagram.com/mindbodygreen/ TikTok: https://www.tiktok.com/@mindbodygreen https://www.youtube-nocookie.com/embed/dUX2w2g_2jQ 2182 2025-09-07T09:00:51.000Z 2026-10-22T17:43:42.560Z https://longevityharbor.com/de/watch/dUX2w2g_2jQ The science behind NAD and NMN: What it means for your health and aging: Andrew Salzman, M.D. https://i.ytimg.com/vi/dUX2w2g_2jQ/hqdefault.jpg Join 1M+ subscribers on their journey towards strong and healthy: https://www.mindbodygreen.com/newsletters “ NAD is the key regulator of the entire metabolic machinery of the body,” explains Andrew Salzman, MD. Andrew Salzman, MD, physician, biomedical entrepreneur, and Chief Medical Officer at Wonderfeel, joins us to explore how optimizing NAD levels could hold the key to slowing aging, enhancing cellular function, and improving healthspan from the inside out. Plus: 0:00 What is NAD? 4:00 When does NAD decline 5:17 The connection to perimenopause & menopause 9:00 The benefits of increasing your levels 12:00 Preventing NAD from breaking down 12:45 What is CD38? 15:00 The impact of NAD on muscle mass 16:05 How to be an informed consumer of NAD supplements 17:45 Salzman’s personal routine 19:00 Dosage & beneficial ingredients in Wonderfeel products 23:15 The benefits on metabolism 24:15 Safety of NAD Referenced in the episode: - Check out Wonderfeel (https://getwonderfeel.com/?utm_source=mbg&utm_medium=podcast) - Learn more about Salzman (https://getwonderfeel.com/experts/andrew-salzman-md/?utm_source=mbg&utm_medium=podcast) - Follow Wonderfeel on Instagram (https://www.instagram.com/getwonderfeel/) - Youngr™ NMN, Wonderfeel’s NAD-boosting supplement (https://getwonderfeel.com/?utm_source=mbg&utm_medium=podcast) ABOUT mbg: mindbodygreen. One word. Here you’ll find a 360-degree approach to wellness that weaves the mental, physical, spiritual, emotional, and environmental aspects of well-being together, because we believe that these pillars of health are all interconnected. Read more here: https://www.mindbodygreen.com/​ Shop our supplements: https://shop.mindbodygreen.com/ Follow us on Social - @mindbodygreen Instagram: https://www.instagram.com/mindbodygreen/ TikTok: https://www.tiktok.com/@mindbodygreen https://www.youtube-nocookie.com/embed/dUX2w2g_2jQ 2182 2025-09-07T09:00:51.000Z 2026-10-22T17:43:42.560Z https://longevityharbor.com/en/watch/dWo0WhGJgXk Video description: rapamycin in animal models of Alzheimer's-like symptoms https://i.ytimg.com/vi/dWo0WhGJgXk/hqdefault.jpg The description says rapamycin reversed Alzheimer's-like symptoms in animal models, restoring cognitive function and boosting motivation by raising key neurotransmitters in the brainstem. These are animal-model results, not demonstrated benefits for people. https://www.youtube-nocookie.com/embed/dWo0WhGJgXk 99 2026-06-17T04:00:50.000Z 2026-10-22T23:57:34.557Z https://longevityharbor.com/de/watch/dWo0WhGJgXk Videobeschreibung: Rapamycin in Tiermodellen mit Alzheimer-ähnlichen Symptomen https://i.ytimg.com/vi/dWo0WhGJgXk/hqdefault.jpg Die Beschreibung sagt, Rapamycin habe Alzheimer-ähnliche Symptome in Tiermodellen umgekehrt, kognitive Funktion wiederhergestellt und die Motivation gesteigert, indem es Schlüssel-Neurotransmitter im Hirnstamm hochregulierte. Das sind Ergebnisse aus Tiermodellen, keine belegten Vorteile für Menschen. https://www.youtube-nocookie.com/embed/dWo0WhGJgXk 99 2026-06-17T04:00:50.000Z 2026-10-22T23:57:34.557Z https://longevityharbor.com/en/watch/dc3HEQsCBp0 Cellular Senescence: The Zombies Inside of You https://i.ytimg.com/vi/dc3HEQsCBp0/hqdefault.jpg #breakthroughjuniorchallenge https://www.youtube-nocookie.com/embed/dc3HEQsCBp0 116 2026-09-16T02:54:10.000Z 2026-10-22T19:21:22.061Z https://longevityharbor.com/de/watch/dc3HEQsCBp0 Cellular Senescence: The Zombies Inside of You https://i.ytimg.com/vi/dc3HEQsCBp0/hqdefault.jpg #breakthroughjuniorchallenge https://www.youtube-nocookie.com/embed/dc3HEQsCBp0 116 2026-09-16T02:54:10.000Z 2026-10-22T19:21:22.061Z https://longevityharbor.com/en/watch/dcTe0ubxugo Senescence | Overview of Cell Senescence | hallmarks and inducers of Cell Senescence | USMLE https://i.ytimg.com/vi/dcTe0ubxugo/hqdefault.jpg This video talks about Senescence. Overview of Cell Senescence | hallmarks and inducers of Cell Senescence | USMLE For Notes, flashcards, daily quizzes, and practice questions follow Instagram page: https://www.instagram.com/animatedbiologywitharpan/ Facebook page: https://www.facebook.com/Animated-biology-with-Arpan-109894017509038/?ref=pages_you_manage Follow me on other social media - Facebook : https://www.facebook.com/arpan.parich... Instagram : https://www.instagram.com/arpanparichha/ Linked in : https://in.linkedin.com/in/arpan-pari... Twitter : https://twitter.com/arpan_parichha?la... Link to my other channel - Lets crack bio exams https://www.youtube.com/channel/UC4IpyopsGWSjaPACNTZLuqg The Nerd Medic YouTube channel: Youtube: https://youtube.com/c/TheNerdMedic00 Instagram: https://instagram.com/ayan_parichha00... Facebook: https://www.facebook.com/poetsoflens/ For Physics part of bio exams - Physics for IIT JAM biotechnology https://www.youtube.com/channel/UCJvSHjOoL2FDN85hQbu7vfw #animated_biology #animated_biology_with_arpan #biology #bio_facts #CSIR_NET #IIT_JAM #IIT_JAM_BT #biotechnology #bioscience #biological_sciences #microbiology #genetics #zoology #molecular_biology #cell_biology #botany #immunology #ecology https://www.youtube-nocookie.com/embed/dcTe0ubxugo 585 2023-08-04T12:30:31.000Z 2026-10-23T02:24:27.094Z https://longevityharbor.com/de/watch/dcTe0ubxugo Senescence | Overview of Cell Senescence | hallmarks and inducers of Cell Senescence | USMLE https://i.ytimg.com/vi/dcTe0ubxugo/hqdefault.jpg This video talks about Senescence. Overview of Cell Senescence | hallmarks and inducers of Cell Senescence | USMLE For Notes, flashcards, daily quizzes, and practice questions follow Instagram page: https://www.instagram.com/animatedbiologywitharpan/ Facebook page: https://www.facebook.com/Animated-biology-with-Arpan-109894017509038/?ref=pages_you_manage Follow me on other social media - Facebook : https://www.facebook.com/arpan.parich... Instagram : https://www.instagram.com/arpanparichha/ Linked in : https://in.linkedin.com/in/arpan-pari... Twitter : https://twitter.com/arpan_parichha?la... Link to my other channel - Lets crack bio exams https://www.youtube.com/channel/UC4IpyopsGWSjaPACNTZLuqg The Nerd Medic YouTube channel: Youtube: https://youtube.com/c/TheNerdMedic00 Instagram: https://instagram.com/ayan_parichha00... Facebook: https://www.facebook.com/poetsoflens/ For Physics part of bio exams - Physics for IIT JAM biotechnology https://www.youtube.com/channel/UCJvSHjOoL2FDN85hQbu7vfw #animated_biology #animated_biology_with_arpan #biology #bio_facts #CSIR_NET #IIT_JAM #IIT_JAM_BT #biotechnology #bioscience #biological_sciences #microbiology #genetics #zoology #molecular_biology #cell_biology #botany #immunology #ecology https://www.youtube-nocookie.com/embed/dcTe0ubxugo 585 2023-08-04T12:30:31.000Z 2026-10-23T02:24:27.094Z https://longevityharbor.com/en/watch/dd1hlxX6HO0 Podcast talk on calorie restriction, metformin, rapamycin and NAD precursors in aging https://i.ytimg.com/vi/dd1hlxX6HO0/hqdefault.jpg In this described podcast episode, Nina Ruge and Prof. Lenhard Rudolph discuss calorie or diet restriction as a robust aging-research intervention, plus stem cells, mitochondria, inflammation, metformin, rapamycin, mTOR and NAD precursors such as NR and NMN, including limits of transferring animal findings to humans. https://www.youtube-nocookie.com/embed/dd1hlxX6HO0 3510 2025-12-26T05:00:06.000Z 2026-10-23T03:09:32.061Z https://longevityharbor.com/de/watch/dd1hlxX6HO0 Podcast-Gespräch über Kalorienrestriktion, Metformin, Rapamycin und NAD-Vorstufen beim Altern https://i.ytimg.com/vi/dd1hlxX6HO0/hqdefault.jpg In dieser beschriebenen Podcast-Folge sprechen Nina Ruge und Prof. Lenhard Rudolph über Kalorien- bzw. Diätrestriktion als robuste Intervention der Alternsforschung sowie über Stammzellen, Mitochondrien, Entzündung, Metformin, Rapamycin, mTOR und NAD-Vorstufen wie NR und NMN, einschließlich der Grenzen der Übertragung von Tiermodellen auf den Menschen. https://www.youtube-nocookie.com/embed/dd1hlxX6HO0 3510 2025-12-26T05:00:06.000Z 2026-10-23T03:09:32.061Z https://longevityharbor.com/en/watch/dgtgKTmbgzY Video description: three daily exercises proposed for people over 60 https://i.ytimg.com/vi/dgtgKTmbgzY/hqdefault.jpg The description presents three home exercises for people over 60, said to target grip strength, lower-leg muscles and upright posture; no results are reported. https://www.youtube-nocookie.com/embed/dgtgKTmbgzY 615 2026-09-27T19:51:31.000Z 2026-10-22T21:43:34.783Z https://longevityharbor.com/de/watch/dgtgKTmbgzY Videobeschreibung: drei tägliche Übungen für Menschen über 60 vorgeschlagen https://i.ytimg.com/vi/dgtgKTmbgzY/hqdefault.jpg Die Beschreibung stellt drei Übungen für zu Hause für Menschen über 60 vor, die auf Griffkraft, Unterschenkelmuskulatur und aufrechte Haltung zielen sollen; Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/dgtgKTmbgzY 615 2026-09-27T19:51:31.000Z 2026-10-22T21:43:34.783Z https://longevityharbor.com/en/watch/dhblfc6dIKY Video description: high-intensity exercise and mitochondria, with an 88-year-old cyclist https://i.ytimg.com/vi/dhblfc6dIKY/hqdefault.jpg The description says short bursts of high-intensity exercise may restore mitochondria and benefit muscles, heart, brain and skin, and presents researcher Matt Robinson and 88-year-old cyclist Norman Lazarus. https://www.youtube-nocookie.com/embed/dhblfc6dIKY 830 2026-08-16T03:53:16.000Z 2026-10-22T23:01:25.632Z https://longevityharbor.com/de/watch/dhblfc6dIKY Videobeschreibung: Hochintensives Training und Mitochondrien, mit einem 88-jährigen Radfahrer https://i.ytimg.com/vi/dhblfc6dIKY/hqdefault.jpg Laut Beschreibung kann kurzes hochintensives Training Mitochondrien wiederherstellen und Muskeln, Herz, Gehirn und Haut zugutekommen; vorgestellt werden Forscher Matt Robinson und der 88-jährige Radfahrer Norman Lazarus. https://www.youtube-nocookie.com/embed/dhblfc6dIKY 830 2026-08-16T03:53:16.000Z 2026-10-22T23:01:25.632Z https://longevityharbor.com/en/watch/dlcg3Ko4sgI Qualia Senolytics description claims to target senescent cells https://i.ytimg.com/vi/dlcg3Ko4sgI/hqdefault.jpg The description says Qualia Senolytics targets senescent 'zombie cells' and, by supporting their clearance, promotes healthier aging, more energy and cellular wellness. These are creator claims; the description reports no study, data or measured outcomes. https://www.youtube-nocookie.com/embed/dlcg3Ko4sgI 109 2025-12-13T14:01:09.000Z 2026-10-23T03:17:05.911Z https://longevityharbor.com/de/watch/dlcg3Ko4sgI Qualia-Senolytics-Beschreibung behauptet, seneszente Zellen anzugreifen https://i.ytimg.com/vi/dlcg3Ko4sgI/hqdefault.jpg Die Beschreibung sagt, Qualia Senolytics greife seneszente „Zombie-Zellen“ an und fördere durch Unterstützung ihrer Beseitigung gesünderes Altern, mehr Energie und zelluläres Wohlbefinden. Das sind Aussagen des Erstellers; die Beschreibung nennt keine Studie, Daten oder gemessene Ergebnisse. https://www.youtube-nocookie.com/embed/dlcg3Ko4sgI 109 2025-12-13T14:01:09.000Z 2026-10-23T03:17:05.911Z https://longevityharbor.com/en/watch/dmDsFU6WMR4 Fasting and its possible role in longevity https://i.ytimg.com/vi/dmDsFU6WMR4/hqdefault.jpg Scientists have been studying the effect on the body's metabolism of fasting, and how it may play into aging. In this web exclusive, "Sunday Morning" correspondent Lee Cowan talks with three researchers on aging – David Sinclair, of Harvard Medical School; Dr. Nir Barzilai, of the Albert Einstein College of Medicine; and Morgan Levine, of the Yale Center for Research on Aging – about the stresses on the body by fasting or caloric restriction, and how it may turn on the body's defenses against aging. https://www.youtube-nocookie.com/embed/dmDsFU6WMR4 245 2021-11-29T00:06:08.000Z 2026-10-22T17:43:38.435Z https://longevityharbor.com/de/watch/dmDsFU6WMR4 Fasting and its possible role in longevity https://i.ytimg.com/vi/dmDsFU6WMR4/hqdefault.jpg Scientists have been studying the effect on the body's metabolism of fasting, and how it may play into aging. In this web exclusive, "Sunday Morning" correspondent Lee Cowan talks with three researchers on aging – David Sinclair, of Harvard Medical School; Dr. Nir Barzilai, of the Albert Einstein College of Medicine; and Morgan Levine, of the Yale Center for Research on Aging – about the stresses on the body by fasting or caloric restriction, and how it may turn on the body's defenses against aging. https://www.youtube-nocookie.com/embed/dmDsFU6WMR4 245 2021-11-29T00:06:08.000Z 2026-10-22T17:43:38.435Z https://longevityharbor.com/en/watch/dtpCcmCjcDc NMN in mice prone to pancreatic disease: what the 2019 study found https://i.ytimg.com/vi/dtpCcmCjcDc/hqdefault.jpg The description says a 2019 NMN study in genetically altered mice predisposed to pancreatic disease raised concerns in that specific model, but does not establish cancer risk or prove safety in healthy people. https://www.youtube-nocookie.com/embed/dtpCcmCjcDc 114 2026-09-21T19:19:09.000Z 2026-10-22T22:02:28.462Z https://longevityharbor.com/de/watch/dtpCcmCjcDc NMN bei Mäusen mit Neigung zu Bauchspeicheldrüsenerkrankung: was die Studie von 2019 fand https://i.ytimg.com/vi/dtpCcmCjcDc/hqdefault.jpg Laut Beschreibung weckte eine NMN-Studie von 2019 bei genetisch veränderten Mäusen mit Neigung zu Bauchspeicheldrüsenerkrankung Bedenken in genau diesem Modell, belegt aber weder ein Krebsrisiko noch Sicherheit bei gesunden Menschen. https://www.youtube-nocookie.com/embed/dtpCcmCjcDc 114 2026-09-21T19:19:09.000Z 2026-10-22T22:02:28.462Z https://longevityharbor.com/en/watch/duU-Xk_fqpU Dr. Valter Longo - The BIG 2025 interview https://i.ytimg.com/vi/duU-Xk_fqpU/hqdefault.jpg 👋🏼 Want to show your support? Subscribe to our channel, hit the notification bell and/or send a Super Thanks! 👋🏼👋🏼👋🏼 Want to show your support and get some extra perks? Become a member! https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA/join 🚀 Special offer for our LEVITY audience: Join Vitalism today and receive a 30% discount on your membership using the code LEVITY at checkout. https://www.vitalism.io/membership 🚀 Show notes for this episode will be available soon after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: reachlevity.com IN THIS EPISODE There were two reasons why Dr. Valter Longo was featured so prominently in my longevity book Evigt Ung (2022). First, if you had to name a single scientific thread running through the history of longevity research, calorie restriction is hard to beat. And few have done more to modernize and translate that insight into real-world practice than Longo. Second, I hold Valter Longo in the highest regard. I've tried his Fasting-Mimicking Diet (FMD), I’ve followed his work on The Longevity Diet, and I find his scientific contributions both rigorous and unusually translational. He doesn’t just publish papers - he builds systems, tests interventions in clinical trials, and tries to implement science into healthcare. In this conversation, we cover the science, history, and application of fasting, nutrition, and longevity - including new work on cancer, metabolism, and organ regeneration. We also discuss the philosophical and political obstacles that stand in the way of real change. What you'll learn in this episode: ✅ The story of Longo’s early music career - and why he left it to study aging. ✅ How calorie restriction shaped modern longevity science. ✅ Why Biosphere 2 and Roy Walford's work was both inspiring and cautionary. ✅ The origins and mechanisms of the Fasting-Mimicking Diet. ✅ What Longo learned about autophagy, stem cells, and organ regeneration. ✅ Why protein intake before and after age 65 should be treated https://www.youtube-nocookie.com/embed/duU-Xk_fqpU 7007 2025-05-20T17:00:54.000Z 2026-10-22T19:54:18.135Z https://longevityharbor.com/de/watch/duU-Xk_fqpU Dr. Valter Longo - The BIG 2025 interview https://i.ytimg.com/vi/duU-Xk_fqpU/hqdefault.jpg 👋🏼 Want to show your support? Subscribe to our channel, hit the notification bell and/or send a Super Thanks! 👋🏼👋🏼👋🏼 Want to show your support and get some extra perks? Become a member! https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA/join 🚀 Special offer for our LEVITY audience: Join Vitalism today and receive a 30% discount on your membership using the code LEVITY at checkout. https://www.vitalism.io/membership 🚀 Show notes for this episode will be available soon after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: reachlevity.com IN THIS EPISODE There were two reasons why Dr. Valter Longo was featured so prominently in my longevity book Evigt Ung (2022). First, if you had to name a single scientific thread running through the history of longevity research, calorie restriction is hard to beat. And few have done more to modernize and translate that insight into real-world practice than Longo. Second, I hold Valter Longo in the highest regard. I've tried his Fasting-Mimicking Diet (FMD), I’ve followed his work on The Longevity Diet, and I find his scientific contributions both rigorous and unusually translational. He doesn’t just publish papers - he builds systems, tests interventions in clinical trials, and tries to implement science into healthcare. In this conversation, we cover the science, history, and application of fasting, nutrition, and longevity - including new work on cancer, metabolism, and organ regeneration. We also discuss the philosophical and political obstacles that stand in the way of real change. What you'll learn in this episode: ✅ The story of Longo’s early music career - and why he left it to study aging. ✅ How calorie restriction shaped modern longevity science. ✅ Why Biosphere 2 and Roy Walford's work was both inspiring and cautionary. ✅ The origins and mechanisms of the Fasting-Mimicking Diet. ✅ What Longo learned about autophagy, stem cells, and organ regeneration. ✅ Why protein intake before and after age 65 should be treated https://www.youtube-nocookie.com/embed/duU-Xk_fqpU 7007 2025-05-20T17:00:54.000Z 2026-10-22T19:54:18.135Z https://longevityharbor.com/en/watch/dvJhxmE8W8w Hayflick Limit: Cellular Senescence Explained in a Short Video https://i.ytimg.com/vi/dvJhxmE8W8w/hqdefault.jpg According to the video description, Leonard Hayflick discovered cellular senescence and showed that mammalian cells are not immortal: they stop dividing after about 40 passages, which challenged earlier assumptions. https://www.youtube-nocookie.com/embed/dvJhxmE8W8w 107 2026-03-24T18:04:39.000Z 2026-10-23T01:52:44.117Z https://longevityharbor.com/de/watch/dvJhxmE8W8w Hayflick-Grenze: Zelluläre Seneszenz in einem Kurzvideo erklärt https://i.ytimg.com/vi/dvJhxmE8W8w/hqdefault.jpg Laut der Videobeschreibung entdeckte Leonard Hayflick die zelluläre Seneszenz und zeigte, dass Säugetierzellen nicht unsterblich sind: Sie teilen sich nach etwa 40 Passagen nicht mehr weiter, was frühere Annahmen infrage stellte. https://www.youtube-nocookie.com/embed/dvJhxmE8W8w 107 2026-03-24T18:04:39.000Z 2026-10-23T01:52:44.117Z https://longevityharbor.com/en/watch/dxbT-ZW4fXA The Anti-Aging Effect of Removing Zombie Cells [7 Studies] https://i.ytimg.com/vi/dxbT-ZW4fXA/hqdefault.jpg *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]* Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST* 1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender Created with Biorender References (Cope & Paste in Search) [1] doi:10.1172/JCI95148 [2] doi:10.1016/j.smim.2019.04.003 [3] doi:10.1093/gerona/glab002 [4] doi:10.1111/acel.13767 [5] doi:10.1007/s11357-023-00830-5 [6] doi:10.2340/actadv.v103.4475 [7] doi:10.1016/j.ebiom.2018.09.015 First Video in this Series: https://youtu.be/6DKQpfqODEg Economist Video: https://www.youtube.com/watch?v=FYr04ymjD1w&t=1s ********CRITIQUES, RULES, AND NOTES******** Be aware of the following rules before posting comments: - Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce). - Please do not comment on Physionic’s finances. I spend thousands of dollars a month and weeks of my time per month to release content for free. If Physionic does not make money, I cannot keep this operation alive; additionally, I work hard and would not expect you to work for free, so do not expect me to work for you for free. Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique: Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached. RULES: If your comment is rude, you will be banned. https://www.youtube-nocookie.com/embed/dxbT-ZW4fXA 611 2023-11-29T13:00:39.000Z 2026-10-22T18:43:13.561Z https://longevityharbor.com/de/watch/dxbT-ZW4fXA The Anti-Aging Effect of Removing Zombie Cells [7 Studies] https://i.ytimg.com/vi/dxbT-ZW4fXA/hqdefault.jpg *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]* Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST* 1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender Created with Biorender References (Cope & Paste in Search) [1] doi:10.1172/JCI95148 [2] doi:10.1016/j.smim.2019.04.003 [3] doi:10.1093/gerona/glab002 [4] doi:10.1111/acel.13767 [5] doi:10.1007/s11357-023-00830-5 [6] doi:10.2340/actadv.v103.4475 [7] doi:10.1016/j.ebiom.2018.09.015 First Video in this Series: https://youtu.be/6DKQpfqODEg Economist Video: https://www.youtube.com/watch?v=FYr04ymjD1w&t=1s ********CRITIQUES, RULES, AND NOTES******** Be aware of the following rules before posting comments: - Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce). - Please do not comment on Physionic’s finances. I spend thousands of dollars a month and weeks of my time per month to release content for free. If Physionic does not make money, I cannot keep this operation alive; additionally, I work hard and would not expect you to work for free, so do not expect me to work for you for free. Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique: Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached. RULES: If your comment is rude, you will be banned. https://www.youtube-nocookie.com/embed/dxbT-ZW4fXA 611 2023-11-29T13:00:39.000Z 2026-10-22T18:43:13.561Z https://longevityharbor.com/en/watch/dzP7G2nHeOg Fasting: Detox, Clarity, Longevity — Backed by Science https://i.ytimg.com/vi/dzP7G2nHeOg/hqdefault.jpg Fasting: Detox, Clarity, Longevity — Backed by Science. Ancient wisdom now confirmed by modern research. 1️⃣ Why Fasting Works Fasting helps flush toxins, burn fat, and sharpen mental clarity by giving your digestive system a break and switching your body into repair mode. 2️⃣ What a 3-Day Water Fast Does After 72 hours, your body undergoes deep cellular cleanup (autophagy), reduces inflammation, and boosts growth hormone. 3️⃣ Benefits at Every Stage 12–16 hrs: Fat burning begins 24 hrs: Blood sugar stabilizes 48 hrs: Inflammation decreases 72 hrs: Immune regeneration kicks in 4️⃣ Boosting Stem Cells Naturally Extended fasting (48–72 hours) increases stem cell production, enhancing regeneration and healing. Credit: The Ultimate Human with Gary Brecka Follow @timelessbear for more wellness science and longevity tips. #FastingBenefits #LongevityScience #Autophagy #GaryBrecka https://www.youtube-nocookie.com/embed/dzP7G2nHeOg 94 2025-05-01T18:45:17.000Z 2026-10-22T19:54:16.728Z https://longevityharbor.com/de/watch/dzP7G2nHeOg Fasting: Detox, Clarity, Longevity — Backed by Science https://i.ytimg.com/vi/dzP7G2nHeOg/hqdefault.jpg Fasting: Detox, Clarity, Longevity — Backed by Science. Ancient wisdom now confirmed by modern research. 1️⃣ Why Fasting Works Fasting helps flush toxins, burn fat, and sharpen mental clarity by giving your digestive system a break and switching your body into repair mode. 2️⃣ What a 3-Day Water Fast Does After 72 hours, your body undergoes deep cellular cleanup (autophagy), reduces inflammation, and boosts growth hormone. 3️⃣ Benefits at Every Stage 12–16 hrs: Fat burning begins 24 hrs: Blood sugar stabilizes 48 hrs: Inflammation decreases 72 hrs: Immune regeneration kicks in 4️⃣ Boosting Stem Cells Naturally Extended fasting (48–72 hours) increases stem cell production, enhancing regeneration and healing. Credit: The Ultimate Human with Gary Brecka Follow @timelessbear for more wellness science and longevity tips. #FastingBenefits #LongevityScience #Autophagy #GaryBrecka https://www.youtube-nocookie.com/embed/dzP7G2nHeOg 94 2025-05-01T18:45:17.000Z 2026-10-22T19:54:16.728Z https://longevityharbor.com/en/watch/dzmEzTMtK0M Hallmarks of Aging: Critical Thinking In The Era Of Anti-Aging Hype https://i.ytimg.com/vi/dzmEzTMtK0M/hqdefault.jpg Hallmarks of Aging Critical Thinking In The Era Of Anti-Aging Hype ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ In this video I discuss the 12 hallmarks of aging discovered by scientists int he field of aging research, or geroscience. I also provide tips on how to evalute longevity science from hype and discuss foundational evidence-based strategies that can slow down biological age, before resorting to exepensive testing, supplements or devices. Ref: 1. https://doi.org/10.1016/j.cell.2013.05.039 2. https://doi.org/10.1016/j.cell.2022.11.001 3. https://doi.org/10.3390/antiox12030651 4. https://doi.org/10.1016/j.molmet.2023.101755 5. https://doi.org/10.1038/s41569-023-00881-3 6. https://doi.org/10.1038/s41380-022-01680-x 7. https://doi.org/10.1016/j.arr.2020.101136 8. https://doi.org/10.1111/febs.16350 9. https://doi.org/10.1101/cshperspect.a041211 10. https://doi.org/10.14283/jfa.2021.5 11. https://doi.org/10.1016/s2666-7568(21)00278-6 12. https://doi.org/10.1111/nyas.14681 13. https://doi.org/10.1016/j.cell.2013.05.039 14. https://doi.org/10.1016/j.cell.2022.11.001 15. https://doi.org/10.2217/epi-2016-0179 16. https://doi.org/10.1186/s13059-019-1753-9 17. https://doi.org/10.1111/acel.14403 18. https://doi.org/10.1038/s43587-024-00600-8 19. https://doi.org/10.1111/acel.13229 20. https://doi.org/10.1016/j.arr.2022.101743 21. https://doi.org/10.1186/s13059-019-1810-4 22. https://doi.org/10.1111/jcmm.17912 23. https://doi.org/10.1111/acel.12338 24. https://doi.org/10.1093/gerona/glab213 25. https://doi.org/10.18632/aging.203051 26. https://doi.org/10.1016/j.clnu.2022.02.023 27. https://doi.org/10.1093/geroni/igac059.1435 28. https://doi.org/10.1093/geroni/igae098.0582 29. https://doi.org/10.1016/j.bbi.2022.05.016 30. https://doi.org/10.1097/PSY.0000000000001264 Video Keywords: Science behind aging process, hallmarks of human aging, debunking anti-aging myths, aging research critical analysis, cellular aging key factors, anti-aging industry exposed, healthy aging lifestyle tips, longevity science evidence ba https://www.youtube-nocookie.com/embed/dzmEzTMtK0M 706 2025-05-14T03:00:06.000Z 2026-10-22T17:43:40.136Z https://longevityharbor.com/de/watch/dzmEzTMtK0M Hallmarks of Aging: Critical Thinking In The Era Of Anti-Aging Hype https://i.ytimg.com/vi/dzmEzTMtK0M/hqdefault.jpg Hallmarks of Aging Critical Thinking In The Era Of Anti-Aging Hype ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ In this video I discuss the 12 hallmarks of aging discovered by scientists int he field of aging research, or geroscience. I also provide tips on how to evalute longevity science from hype and discuss foundational evidence-based strategies that can slow down biological age, before resorting to exepensive testing, supplements or devices. Ref: 1. https://doi.org/10.1016/j.cell.2013.05.039 2. https://doi.org/10.1016/j.cell.2022.11.001 3. https://doi.org/10.3390/antiox12030651 4. https://doi.org/10.1016/j.molmet.2023.101755 5. https://doi.org/10.1038/s41569-023-00881-3 6. https://doi.org/10.1038/s41380-022-01680-x 7. https://doi.org/10.1016/j.arr.2020.101136 8. https://doi.org/10.1111/febs.16350 9. https://doi.org/10.1101/cshperspect.a041211 10. https://doi.org/10.14283/jfa.2021.5 11. https://doi.org/10.1016/s2666-7568(21)00278-6 12. https://doi.org/10.1111/nyas.14681 13. https://doi.org/10.1016/j.cell.2013.05.039 14. https://doi.org/10.1016/j.cell.2022.11.001 15. https://doi.org/10.2217/epi-2016-0179 16. https://doi.org/10.1186/s13059-019-1753-9 17. https://doi.org/10.1111/acel.14403 18. https://doi.org/10.1038/s43587-024-00600-8 19. https://doi.org/10.1111/acel.13229 20. https://doi.org/10.1016/j.arr.2022.101743 21. https://doi.org/10.1186/s13059-019-1810-4 22. https://doi.org/10.1111/jcmm.17912 23. https://doi.org/10.1111/acel.12338 24. https://doi.org/10.1093/gerona/glab213 25. https://doi.org/10.18632/aging.203051 26. https://doi.org/10.1016/j.clnu.2022.02.023 27. https://doi.org/10.1093/geroni/igac059.1435 28. https://doi.org/10.1093/geroni/igae098.0582 29. https://doi.org/10.1016/j.bbi.2022.05.016 30. https://doi.org/10.1097/PSY.0000000000001264 Video Keywords: Science behind aging process, hallmarks of human aging, debunking anti-aging myths, aging research critical analysis, cellular aging key factors, anti-aging industry exposed, healthy aging lifestyle tips, longevity science evidence ba https://www.youtube-nocookie.com/embed/dzmEzTMtK0M 706 2025-05-14T03:00:06.000Z 2026-10-22T17:43:40.136Z https://longevityharbor.com/en/watch/e-if3zjYSfY mTOR-Driven Aging and Rapamycin with Mikhail Blagosklonny and Dennis Mangan [SHORT VERSION] https://i.ytimg.com/vi/e-if3zjYSfY/hqdefault.jpg Dr. Mikhail Blagosklonny is a professor of oncology who now studies aging, and is the originator of the hyperfunction theory of aging. He has written numerous scientific articles on aging and, in particular, on the extension of lifespan with rapamycin. Here, he and Dennis Mangan discuss how Dr. Blagosklonny's cancer research led him to the study of aging, whether rapamycin is the most important anti-aging intervention currently available, his skepticism about metformin as an anti-aging drug, and more. Video transcript: https://aging-us.net/2022/06/15/interview-mtor-driven-aging-and-rapamycin/ In remembrance of Dr. Blagosklonny: https://www.aging-us.com/mikhail-blagosklonny Keywords: rapamycin, mTOR, aging, longevity, oncology To learn more about Aging, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM https://www.youtube-nocookie.com/embed/e-if3zjYSfY 1544 2021-10-06T14:10:56.000Z 2026-10-22T17:43:41.757Z https://longevityharbor.com/de/watch/e-if3zjYSfY mTOR-Driven Aging and Rapamycin with Mikhail Blagosklonny and Dennis Mangan [SHORT VERSION] https://i.ytimg.com/vi/e-if3zjYSfY/hqdefault.jpg Dr. Mikhail Blagosklonny is a professor of oncology who now studies aging, and is the originator of the hyperfunction theory of aging. He has written numerous scientific articles on aging and, in particular, on the extension of lifespan with rapamycin. Here, he and Dennis Mangan discuss how Dr. Blagosklonny's cancer research led him to the study of aging, whether rapamycin is the most important anti-aging intervention currently available, his skepticism about metformin as an anti-aging drug, and more. Video transcript: https://aging-us.net/2022/06/15/interview-mtor-driven-aging-and-rapamycin/ In remembrance of Dr. Blagosklonny: https://www.aging-us.com/mikhail-blagosklonny Keywords: rapamycin, mTOR, aging, longevity, oncology To learn more about Aging, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM https://www.youtube-nocookie.com/embed/e-if3zjYSfY 1544 2021-10-06T14:10:56.000Z 2026-10-22T17:43:41.757Z https://longevityharbor.com/en/watch/e1lcGVIojFY Stem Cells, Aging Hallmarks & Rapamycin | 49 - Kevin White https://i.ytimg.com/vi/e1lcGVIojFY/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Check out Prime Health Associates: https://www.primehealthassociates.com/ Matt recently attended the 52nd annual meeting of the American Aging Association in Madison, Wisconsin and met with several people doing fascinating work in or adjacent to the gerosciencefield. One of these was Kevin White, physician at longevity-focused clinic Prime Health Associates in Oklahoma City, Oklahoma. Kevin spent two decades in emergency medicine before obtaining fellowship training in integrative and functional medicine, nutrition, and age management. He complete residency training in emergency medicine and trauma at Washington University in St. Louis, and received his M.D. from the University of Oklahoma College of Medicine. Matt describes him as "one of the few longevity docs who actually comes to the science meetings to learn more about the science of aging." Ultimately, the geroscience field is nothing without the medical professionals who bring new discoveries to bedside. So we really enjoyed sitting down with Kevin and hearing his thoughts on interventions such as stem cell therapy as well as his questions about the geroscience field, which prompted a wide-ranging discussion of rapamycin, the hallmarks of aging, body composition, and more. 0:00 Introduction 3:30 How does rapamycin actually work? What is mTOR? 7:51 The two flavors of mTOR 9:25 What we know about rapamycin's effects on model organisms and humans 16:52 Rapamycin's effects on klotho levels 18:48 Can Matt name the 12 hallmarks of aging? 21:28 Matt's views on stem cell exhaustion/stem cell therapy 26:19 Kevin's views on stem cell therapy 28:13 Environmental factors that might reduce stem cell exhaustion 30:40 Geroscience research that excites Matt + rapamycin research in primates 32:50 Matt's current body composition stats and goals 37:17 Wrapping up Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely fo https://www.youtube-nocookie.com/embed/e1lcGVIojFY 2275 2024-07-16T14:00:28.000Z 2026-10-22T17:43:40.139Z https://longevityharbor.com/de/watch/e1lcGVIojFY Stem Cells, Aging Hallmarks & Rapamycin | 49 - Kevin White https://i.ytimg.com/vi/e1lcGVIojFY/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Check out Prime Health Associates: https://www.primehealthassociates.com/ Matt recently attended the 52nd annual meeting of the American Aging Association in Madison, Wisconsin and met with several people doing fascinating work in or adjacent to the gerosciencefield. One of these was Kevin White, physician at longevity-focused clinic Prime Health Associates in Oklahoma City, Oklahoma. Kevin spent two decades in emergency medicine before obtaining fellowship training in integrative and functional medicine, nutrition, and age management. He complete residency training in emergency medicine and trauma at Washington University in St. Louis, and received his M.D. from the University of Oklahoma College of Medicine. Matt describes him as "one of the few longevity docs who actually comes to the science meetings to learn more about the science of aging." Ultimately, the geroscience field is nothing without the medical professionals who bring new discoveries to bedside. So we really enjoyed sitting down with Kevin and hearing his thoughts on interventions such as stem cell therapy as well as his questions about the geroscience field, which prompted a wide-ranging discussion of rapamycin, the hallmarks of aging, body composition, and more. 0:00 Introduction 3:30 How does rapamycin actually work? What is mTOR? 7:51 The two flavors of mTOR 9:25 What we know about rapamycin's effects on model organisms and humans 16:52 Rapamycin's effects on klotho levels 18:48 Can Matt name the 12 hallmarks of aging? 21:28 Matt's views on stem cell exhaustion/stem cell therapy 26:19 Kevin's views on stem cell therapy 28:13 Environmental factors that might reduce stem cell exhaustion 30:40 Geroscience research that excites Matt + rapamycin research in primates 32:50 Matt's current body composition stats and goals 37:17 Wrapping up Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely fo https://www.youtube-nocookie.com/embed/e1lcGVIojFY 2275 2024-07-16T14:00:28.000Z 2026-10-22T17:43:40.139Z https://longevityharbor.com/en/watch/eEv6m_3KRZg Senolytics A New Frontier in Anti Ageing https://i.ytimg.com/vi/eEv6m_3KRZg/hqdefault.jpg Senolytics A New Frontier in Anti Ageing https://www.youtube-nocookie.com/embed/eEv6m_3KRZg 114 2025-03-15T06:30:18.000Z 2026-10-22T19:43:47.741Z https://longevityharbor.com/de/watch/eEv6m_3KRZg Senolytics A New Frontier in Anti Ageing https://i.ytimg.com/vi/eEv6m_3KRZg/hqdefault.jpg Senolytics A New Frontier in Anti Ageing https://www.youtube-nocookie.com/embed/eEv6m_3KRZg 114 2025-03-15T06:30:18.000Z 2026-10-22T19:43:47.741Z https://longevityharbor.com/en/watch/eH6gC-tQIfs AGE Presents: Matt Kaeberlein - An Introduction to the Biology of Aging. https://i.ytimg.com/vi/eH6gC-tQIfs/hqdefault.jpg Matt Kaeberlein, Professor of Laboratory Medicine and Pathology at the University of Washington, director of the Healthy Aging and Longevity (HALo) Research Institute, and CEO of the American Aging Association, gives a broad introduction to the Biology of Aging and discusses the effects of rapamycin on biological age. This video is an introduction to the "AGE Presents:" lecture series Join AGE at https://www.americanagingassociation.org/ https://www.youtube-nocookie.com/embed/eH6gC-tQIfs 3254 2021-05-18T07:00:06.000Z 2026-10-22T17:43:40.101Z https://longevityharbor.com/de/watch/eH6gC-tQIfs AGE Presents: Matt Kaeberlein - An Introduction to the Biology of Aging. https://i.ytimg.com/vi/eH6gC-tQIfs/hqdefault.jpg Matt Kaeberlein, Professor of Laboratory Medicine and Pathology at the University of Washington, director of the Healthy Aging and Longevity (HALo) Research Institute, and CEO of the American Aging Association, gives a broad introduction to the Biology of Aging and discusses the effects of rapamycin on biological age. This video is an introduction to the "AGE Presents:" lecture series Join AGE at https://www.americanagingassociation.org/ https://www.youtube-nocookie.com/embed/eH6gC-tQIfs 3254 2021-05-18T07:00:06.000Z 2026-10-22T17:43:40.101Z https://longevityharbor.com/en/watch/eKv60BHYITE Neuroscientist David Cox on breathing, diet and healthy aging claims https://i.ytimg.com/vi/eKv60BHYITE/hqdefault.jpg In this video description, neuroscientist David Cox discusses lung capacity as a possible aging marker, breathwork and stress, and diet topics such as AGEs, micronutrients and fiber, while warning about exaggerated longevity claims. https://www.youtube-nocookie.com/embed/eKv60BHYITE 3228 2026-09-01T08:58:58.000Z 2026-10-22T22:35:42.455Z https://longevityharbor.com/de/watch/eKv60BHYITE Neurowissenschaftler David Cox über Atmung, Ernährung und Alternsversprechen https://i.ytimg.com/vi/eKv60BHYITE/hqdefault.jpg In dieser Videobeschreibung spricht der Neurowissenschaftler David Cox über Lungenkapazität als möglichen Alternsmarker, Atemarbeit und Stress sowie Ernährungsthemen wie AGEs, Mikronährstoffe und Ballaststoffe – und warnt vor übertriebenen Langlebigkeitsversprechen. https://www.youtube-nocookie.com/embed/eKv60BHYITE 3228 2026-09-01T08:58:58.000Z 2026-10-22T22:35:42.455Z https://longevityharbor.com/en/watch/eM7dwqPFWE4 Video description: NAD, aging and supplement forms explained by Dr. A https://i.ytimg.com/vi/eM7dwqPFWE4/hqdefault.jpg The description says Dr. A explains NAD's roles in mitochondrial energy, DNA repair and cell communication, why levels decline with age, and differences between niacinamide, NMN, NR and IV NAD. It is a description only; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/eM7dwqPFWE4 519 2026-01-30T21:00:47.000Z 2026-10-23T02:41:51.659Z https://longevityharbor.com/de/watch/eM7dwqPFWE4 Videobeschreibung: NAD, Altern und Supplementformen laut Dr. A erklärt https://i.ytimg.com/vi/eM7dwqPFWE4/hqdefault.jpg Laut Beschreibung erklärt Dr. A die Rollen von NAD bei mitochondrialer Energie, DNA-Reparatur und Zellkommunikation, warum die Werte mit dem Alter sinken, und Unterschiede zwischen Niacinamid, NMN, NR und IV-NAD. Es ist nur eine Beschreibung; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/eM7dwqPFWE4 519 2026-01-30T21:00:47.000Z 2026-10-23T02:41:51.659Z https://longevityharbor.com/en/watch/eNUEPM3PqrQ Video description on geroscience: hallmarks, epigenetic clocks and the TAME metformin trial https://i.ytimg.com/vi/eNUEPM3PqrQ/hqdefault.jpg The description says the listed sources cover the twelve hallmarks of ageing, epigenetic clocks such as GrimAge for predicting mortality, the TAME trial on metformin's anti-ageing potential, and partial cellular reprogramming; it frames ageing as potentially modifiable. https://www.youtube-nocookie.com/embed/eNUEPM3PqrQ 448 2026-04-08T08:59:11.000Z 2026-10-23T01:38:07.115Z https://longevityharbor.com/de/watch/eNUEPM3PqrQ Videobeschreibung zur Gerowissenschaft: Hallmarks, epigenetische Uhren und die TAME-Metformin-Studie https://i.ytimg.com/vi/eNUEPM3PqrQ/hqdefault.jpg Laut Beschreibung behandeln die genannten Quellen die zwölf Hallmarks des Alterns, epigenetische Uhren wie GrimAge zur Vorhersage der Sterblichkeit, die TAME-Studie zum Anti-Aging-Potenzial von Metformin und partielle zelluläre Reprogrammierung; Altern wird als möglicherweise veränderbarer Prozess dargestellt. https://www.youtube-nocookie.com/embed/eNUEPM3PqrQ 448 2026-04-08T08:59:11.000Z 2026-10-23T01:38:07.115Z https://longevityharbor.com/en/watch/eOAeUcn2YAE Video description: NMN, NAD⁺ and Australia's TGA rules discussed https://i.ytimg.com/vi/eOAeUcn2YAE/hqdefault.jpg The description says Lucy Canny joins two pharmacists to discuss what NMN is, how it relates to NAD⁺ and cellular energy, evidence versus online hype, TGA regulation and lifestyle foundations. The video itself was not reviewed. https://www.youtube-nocookie.com/embed/eOAeUcn2YAE 844 2026-06-29T02:59:18.000Z 2026-10-22T23:46:08.085Z https://longevityharbor.com/de/watch/eOAeUcn2YAE Videobeschreibung: NMN, NAD⁺ und Australiens TGA-Regeln im Gespräch https://i.ytimg.com/vi/eOAeUcn2YAE/hqdefault.jpg Laut Beschreibung spricht Lucy Canny mit zwei Apothekerinnen darüber, was NMN ist, wie es mit NAD⁺ und zellulärer Energie zusammenhängt, Evidenz gegenüber Online-Hype, die TGA-Regulierung und Grundlagen des Lebensstils. Das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/eOAeUcn2YAE 844 2026-06-29T02:59:18.000Z 2026-10-22T23:46:08.085Z https://longevityharbor.com/en/watch/eOVnAJwMWJs Healthy Aging MasterClass | Build Muscle, Stay Mobile & Live Longer https://i.ytimg.com/vi/eOVnAJwMWJs/hqdefault.jpg 📩 Get Dr. Vonda’s insights Want to understand what’s happening in your body — and what to do next? Each week, Dr. Vonda shares science-backed guidance on strength, bone health, muscle, and longevity — the same way she speaks to her patients. Clear. Practical. No noise. 👉 Join the newsletter: https://manage.kmail-lists.com/subscriptions/subscribe?a=YqJKtR&g=Ww3gx3&utm_source=Youtube&utm_medium=video&utm_campaign=aging-masterclass-24-july-26 Movement isn't a supplement to your health plan. It is the plan. In this masterclass, I break down why sedentary living is one of the most dangerous choices a woman can make in midlife, the masters athlete studies that reframe what aging actually looks like, and the MRI images that show the difference between lean muscle and fatty tissue at any age, why estrogen falls fast, what that does to your joints and muscle, and why 35 to 45 is the critical decade and why FACE framework, is my practical blueprint for flexibility, aerobic work, carrying load, and equilibrium. What we cover: - Sedentary death syndrome and the 33 chronic diseases linked to inactivity - Mitochondria, senescent cells, and inflammation in aging - Why aging research is skewed by sedentary study populations - PRIMA masters athlete studies, ages 35 to 103 - MRI muscle scans: lean tissue vs fatty infiltration - The critical decade: why 35 to 45 matters most - Testosterone decline vs estrogen drop in perimenopause - Menopause musculoskeletal pain and hormone fluctuation - Muscle mass and VO2 max for female longevity - HIIT and training intensity for women over 40 - The FACE framework: flexibility, aerobic, carry, equilibrium - Balance and foot speed drills for fall prevention Timestamp 00:00 Why Movement Is Medicine for Aging 03:58 Why Aging Studies Get It Wrong 06:53 MRI Scans Prove Muscle Loss Isn't Inevitable 09:36 Why 35 to 45 Is Your Critical Decade 13:44 How Male and Female Hormones Decline Differently 16:30 Why Estrogen Affects Every Organ in Your Body 19:35 Why Women Live Longer but Suffer More 22:01 https://www.youtube-nocookie.com/embed/eOVnAJwMWJs 2166 2026-07-24T11:00:10.000Z 2026-10-22T17:43:36.913Z https://longevityharbor.com/de/watch/eOVnAJwMWJs Healthy Aging MasterClass | Build Muscle, Stay Mobile & Live Longer https://i.ytimg.com/vi/eOVnAJwMWJs/hqdefault.jpg 📩 Get Dr. Vonda’s insights Want to understand what’s happening in your body — and what to do next? Each week, Dr. Vonda shares science-backed guidance on strength, bone health, muscle, and longevity — the same way she speaks to her patients. Clear. Practical. No noise. 👉 Join the newsletter: https://manage.kmail-lists.com/subscriptions/subscribe?a=YqJKtR&g=Ww3gx3&utm_source=Youtube&utm_medium=video&utm_campaign=aging-masterclass-24-july-26 Movement isn't a supplement to your health plan. It is the plan. In this masterclass, I break down why sedentary living is one of the most dangerous choices a woman can make in midlife, the masters athlete studies that reframe what aging actually looks like, and the MRI images that show the difference between lean muscle and fatty tissue at any age, why estrogen falls fast, what that does to your joints and muscle, and why 35 to 45 is the critical decade and why FACE framework, is my practical blueprint for flexibility, aerobic work, carrying load, and equilibrium. What we cover: - Sedentary death syndrome and the 33 chronic diseases linked to inactivity - Mitochondria, senescent cells, and inflammation in aging - Why aging research is skewed by sedentary study populations - PRIMA masters athlete studies, ages 35 to 103 - MRI muscle scans: lean tissue vs fatty infiltration - The critical decade: why 35 to 45 matters most - Testosterone decline vs estrogen drop in perimenopause - Menopause musculoskeletal pain and hormone fluctuation - Muscle mass and VO2 max for female longevity - HIIT and training intensity for women over 40 - The FACE framework: flexibility, aerobic, carry, equilibrium - Balance and foot speed drills for fall prevention Timestamp 00:00 Why Movement Is Medicine for Aging 03:58 Why Aging Studies Get It Wrong 06:53 MRI Scans Prove Muscle Loss Isn't Inevitable 09:36 Why 35 to 45 Is Your Critical Decade 13:44 How Male and Female Hormones Decline Differently 16:30 Why Estrogen Affects Every Organ in Your Body 19:35 Why Women Live Longer but Suffer More 22:01 https://www.youtube-nocookie.com/embed/eOVnAJwMWJs 2166 2026-07-24T11:00:10.000Z 2026-10-22T17:43:36.913Z https://longevityharbor.com/en/watch/ePxCeKXsD44 Protein: How Much and What Kind Is Best for Healthy Aging | Educational Video | Biolayne https://i.ytimg.com/vi/ePxCeKXsD44/hqdefault.jpg Original Study: https://ajcn.nutrition.org/article/S0002-9165(23)66282-3/pdf Get my research review REPS: biolayne.com/REPS Get my new nutrition coaching app, Carbon Diet Coach: http://onelink.to/9h4d62 My research based supplements: http://www.outworknutrition.com Get my books on how to lose fat: http://www.biolaynestore.com Take my online course "The Science of Nutrition": https://chfi.click/laynenorton_online Get Custom Workouts by me for $12.99/month: https://biolayne.com/workout-builder/ http://www.facebook.com/laynenorton http://www.twitter.com/biolayne http://www.instagram.com/biolayne https://www.youtube-nocookie.com/embed/ePxCeKXsD44 724 2024-05-22T19:00:25.000Z 2026-10-22T18:43:11.701Z https://longevityharbor.com/de/watch/ePxCeKXsD44 Protein: How Much and What Kind Is Best for Healthy Aging | Educational Video | Biolayne https://i.ytimg.com/vi/ePxCeKXsD44/hqdefault.jpg Original Study: https://ajcn.nutrition.org/article/S0002-9165(23)66282-3/pdf Get my research review REPS: biolayne.com/REPS Get my new nutrition coaching app, Carbon Diet Coach: http://onelink.to/9h4d62 My research based supplements: http://www.outworknutrition.com Get my books on how to lose fat: http://www.biolaynestore.com Take my online course "The Science of Nutrition": https://chfi.click/laynenorton_online Get Custom Workouts by me for $12.99/month: https://biolayne.com/workout-builder/ http://www.facebook.com/laynenorton http://www.twitter.com/biolayne http://www.instagram.com/biolayne https://www.youtube-nocookie.com/embed/ePxCeKXsD44 724 2024-05-22T19:00:25.000Z 2026-10-22T18:43:11.701Z https://longevityharbor.com/en/watch/eQLkBhOhtYI The Circadian Rhythm Secret Every High Performer Is Missing | Be Hard to Kill Series with Dr. Evan https://i.ytimg.com/vi/eQLkBhOhtYI/hqdefault.jpg 💤 Be Hard to Kill Series | Why We Sleep with Dr. Evan Pridmore “Sleep isn’t a luxury. It’s your most powerful healing tool.” In this episode of the Be Hard to Kill Series, Dr. Evan Pridmore from TruRoots Health Center dives deep into the science of sleep, inspired by Matthew Walker’s groundbreaking research Why We Sleep. 🧠 You’ll Learn: Why poor sleep affects every system of your body, from hormones and metabolism to mood and immunity. How blue light, caffeine and stress sabotage your sleep cycles. What happens to your brain during deep and REM sleep (and why missing them accelerates aging). How to prepare for the time change and keep your circadian rhythm balanced. Practical, science-backed tips for improving sleep naturally - no pills, no gimmicks. 🌿 About the Be Hard to Kill Series: Hosted by Dr. Evan Pridmore, this monthly in-office and online seminar series explores the foundations of long-term resilience and health, including nervous system function, stress response, gut health, hormone balance, and more. 💪 Become harder to kill by sleeping smarter, thinking clearer, and healing deeper. 📍 Presented by: TruRoots Health Center | Mt. Juliet, TN 1020 Meb Ct #100, Mt. Juliet, TN 37122 📞 (615) 583-9788 🌐 trurootshealth.com Follow us for more health insights: 📘 Facebook: facebook.com/chiropractormountjuliet 📸 Instagram: instagram.com/trurootshealthcenter 🎵 TikTok: tiktok.com/@trurootshealth 👉 Subscribe for more educational talks on holistic health, chiropractic biophysics, nervous system optimization, and the NURTURE™ Healing Framework. #BeHardToKill #WhyWeSleep #SleepScience #DrEvanPridmore #TruRootsHealth #FunctionalMedicine #MtJulietTN #CircadianRhythm #MatthewWalker #HolisticHealth #BlueLight #SleepBetter #naturalhealing https://www.youtube-nocookie.com/embed/eQLkBhOhtYI 5652 2025-10-05T12:25:39.000Z 2026-10-22T18:54:02.221Z https://longevityharbor.com/de/watch/eQLkBhOhtYI The Circadian Rhythm Secret Every High Performer Is Missing | Be Hard to Kill Series with Dr. Evan https://i.ytimg.com/vi/eQLkBhOhtYI/hqdefault.jpg 💤 Be Hard to Kill Series | Why We Sleep with Dr. Evan Pridmore “Sleep isn’t a luxury. It’s your most powerful healing tool.” In this episode of the Be Hard to Kill Series, Dr. Evan Pridmore from TruRoots Health Center dives deep into the science of sleep, inspired by Matthew Walker’s groundbreaking research Why We Sleep. 🧠 You’ll Learn: Why poor sleep affects every system of your body, from hormones and metabolism to mood and immunity. How blue light, caffeine and stress sabotage your sleep cycles. What happens to your brain during deep and REM sleep (and why missing them accelerates aging). How to prepare for the time change and keep your circadian rhythm balanced. Practical, science-backed tips for improving sleep naturally - no pills, no gimmicks. 🌿 About the Be Hard to Kill Series: Hosted by Dr. Evan Pridmore, this monthly in-office and online seminar series explores the foundations of long-term resilience and health, including nervous system function, stress response, gut health, hormone balance, and more. 💪 Become harder to kill by sleeping smarter, thinking clearer, and healing deeper. 📍 Presented by: TruRoots Health Center | Mt. Juliet, TN 1020 Meb Ct #100, Mt. Juliet, TN 37122 📞 (615) 583-9788 🌐 trurootshealth.com Follow us for more health insights: 📘 Facebook: facebook.com/chiropractormountjuliet 📸 Instagram: instagram.com/trurootshealthcenter 🎵 TikTok: tiktok.com/@trurootshealth 👉 Subscribe for more educational talks on holistic health, chiropractic biophysics, nervous system optimization, and the NURTURE™ Healing Framework. #BeHardToKill #WhyWeSleep #SleepScience #DrEvanPridmore #TruRootsHealth #FunctionalMedicine #MtJulietTN #CircadianRhythm #MatthewWalker #HolisticHealth #BlueLight #SleepBetter #naturalhealing https://www.youtube-nocookie.com/embed/eQLkBhOhtYI 5652 2025-10-05T12:25:39.000Z 2026-10-22T18:54:02.221Z https://longevityharbor.com/en/watch/eT-EDr6CcBE Factory video explains NMN as an NAD+ building block https://i.ytimg.com/vi/eT-EDr6CcBE/hqdefault.jpg The description presents NMN as a building block the body uses to make NAD+, which helps carry energy in cells; it says NAD+ declines with age and that NMN supplements supply more raw material. https://www.youtube-nocookie.com/embed/eT-EDr6CcBE 105 2026-08-02T08:00:05.000Z 2026-10-22T23:16:08.240Z https://longevityharbor.com/de/watch/eT-EDr6CcBE Fabrikvideo erklärt NMN als Baustein für NAD+ https://i.ytimg.com/vi/eT-EDr6CcBE/hqdefault.jpg Die Beschreibung stellt NMN als Baustein dar, den der Körper zur NAD+-Bildung nutzt; NAD+ helfe, Energie in Zellen zu transportieren. Mit dem Alter sinke NAD+, und NMN-Präparate lieferten mehr Rohmaterial. https://www.youtube-nocookie.com/embed/eT-EDr6CcBE 105 2026-08-02T08:00:05.000Z 2026-10-22T23:16:08.240Z https://longevityharbor.com/en/watch/eUcu9jt5rpU Epigenetic clocks: DNA methylation, biological age and what the evidence shows https://i.ytimg.com/vi/eUcu9jt5rpU/hqdefault.jpg The video description explains how epigenetic clocks estimate biological age from DNA methylation, notes links to future health, and separates small trials and mouse work from proven human benefits. https://www.youtube-nocookie.com/embed/eUcu9jt5rpU 448 2026-06-14T13:00:37.000Z 2026-10-23T00:01:41.606Z https://longevityharbor.com/de/watch/eUcu9jt5rpU Epigenetische Uhren: DNA-Methylierung, biologisches Alter und was die Belege zeigen https://i.ytimg.com/vi/eUcu9jt5rpU/hqdefault.jpg Die Videobeschreibung erklärt, wie epigenetische Uhren das biologische Alter aus DNA-Methylierung schätzen, nennt Bezüge zur künftigen Gesundheit und trennt kleine Studien und Mausarbeit von belegtem Nutzen beim Menschen. https://www.youtube-nocookie.com/embed/eUcu9jt5rpU 448 2026-06-14T13:00:37.000Z 2026-10-23T00:01:41.606Z https://longevityharbor.com/en/watch/eUkiKq87-kE Video description: low-dose rapamycin and DNA damage in human T cells https://i.ytimg.com/vi/eUkiKq87-kE/hqdefault.jpg The description presents a 2026 Oxford and Nottingham laboratory study reporting that low-dose rapamycin reduced DNA double-strand breaks by over 40% in human T cells under severe genotoxic stress, plus results from an attached 4-month placebo-controlled trial in older adults. https://www.youtube-nocookie.com/embed/eUkiKq87-kE 513 2026-09-10T14:25:19.000Z 2026-10-22T22:18:31.068Z https://longevityharbor.com/de/watch/eUkiKq87-kE Videobeschreibung: niedrig dosiertes Rapamycin und DNA-Schäden in menschlichen T-Zellen https://i.ytimg.com/vi/eUkiKq87-kE/hqdefault.jpg Die Beschreibung stellt eine Laborstudie von Oxford und Nottingham aus 2026 vor, laut der niedrig dosiertes Rapamycin DNA-Doppelstrangbrüche in menschlichen T-Zellen unter starkem genotoxischem Stress um über 40 % senkte, sowie Ergebnisse einer angeschlossenen 4-monatigen placebokontrollierten Studie bei älteren Erwachsenen. https://www.youtube-nocookie.com/embed/eUkiKq87-kE 513 2026-09-10T14:25:19.000Z 2026-10-22T22:18:31.068Z https://longevityharbor.com/en/watch/eZwPgF-HB3c Video description on epigenetic clocks, biological age and lifestyle claims https://i.ytimg.com/vi/eZwPgF-HB3c/hqdefault.jpg The description presents epigenetic clocks as molecular timers based on DNA methylation that are said to reveal biological age and health risk. It also lists lifestyle factors and supplements as possible ways to slow or reverse the clock, but gives no study results or safety evidence. https://www.youtube-nocookie.com/embed/eZwPgF-HB3c 957 2026-02-04T16:00:06.000Z 2026-10-23T02:38:37.419Z https://longevityharbor.com/de/watch/eZwPgF-HB3c Videobeschreibung zu epigenetischen Uhren, biologischem Alter und Lebensstil-Aussagen https://i.ytimg.com/vi/eZwPgF-HB3c/hqdefault.jpg Die Beschreibung stellt epigenetische Uhren als molekulare Zeitmesser auf Basis von DNA-Methylierung vor, die biologisches Alter und Gesundheitsrisiko anzeigen sollen. Sie nennt außerdem Lebensstilfaktoren und Nahrungsergänzungsmittel als mögliche Wege, die Uhr zu verlangsamen oder umzukehren, ohne Studienergebnisse oder Sicherheitsbelege zu liefern. https://www.youtube-nocookie.com/embed/eZwPgF-HB3c 957 2026-02-04T16:00:06.000Z 2026-10-23T02:38:37.419Z https://longevityharbor.com/en/watch/ehgcNCyfOPY Fasting and Longevity: The Science of Caloric Restriction https://i.ytimg.com/vi/ehgcNCyfOPY/hqdefault.jpg In this deep dive we focus on an article from USC Leonard Davis School of Gerontology explores the science behind fasting and its potential to promote longevity and combat disease. It highlights the work of Professor Valter Longo, a pioneer in fasting-mimicking diets. Longo's research suggests that these diets can trigger cellular repair and improve overall health. The piece also discusses different types of intermittent fasting and emphasizes the importance of medical supervision before undertaking any fasting regimen. The article further summarizes clinical trials that are being done on intermittent fasting. It concludes by suggesting that smaller dietary changes, like reducing animal protein, are more sustainable and can still yield positive results. https://www.youtube-nocookie.com/embed/ehgcNCyfOPY 642 2025-03-13T21:49:42.000Z 2026-10-22T18:32:09.948Z https://longevityharbor.com/de/watch/ehgcNCyfOPY Fasting and Longevity: The Science of Caloric Restriction https://i.ytimg.com/vi/ehgcNCyfOPY/hqdefault.jpg In this deep dive we focus on an article from USC Leonard Davis School of Gerontology explores the science behind fasting and its potential to promote longevity and combat disease. It highlights the work of Professor Valter Longo, a pioneer in fasting-mimicking diets. Longo's research suggests that these diets can trigger cellular repair and improve overall health. The piece also discusses different types of intermittent fasting and emphasizes the importance of medical supervision before undertaking any fasting regimen. The article further summarizes clinical trials that are being done on intermittent fasting. It concludes by suggesting that smaller dietary changes, like reducing animal protein, are more sustainable and can still yield positive results. https://www.youtube-nocookie.com/embed/ehgcNCyfOPY 642 2025-03-13T21:49:42.000Z 2026-10-22T18:32:09.948Z https://longevityharbor.com/en/watch/epGV9bKN6Ec Interview description: Willett on diet, longevity and chronic disease https://i.ytimg.com/vi/epGV9bKN6Ec/hqdefault.jpg The description presents an interview with Dr. Walter Willett, Professor of Nutrition at Harvard, said to be the most cited nutrition scientist, drawing on the Nurses' Health Study and the Health Professionals Follow-up Study. It says the talk covers whole grains versus potatoes, beef as a protein source, and a 1993 trans-fat paper. https://www.youtube-nocookie.com/embed/epGV9bKN6Ec 3802 2026-03-20T13:02:28.000Z 2026-10-23T01:59:45.387Z https://longevityharbor.com/de/watch/epGV9bKN6Ec Interviewbeschreibung: Willett über Ernährung, Langlebigkeit und chronische Krankheiten https://i.ytimg.com/vi/epGV9bKN6Ec/hqdefault.jpg Die Beschreibung stellt ein Interview mit Dr. Walter Willett vor, Professor für Ernährung an der Harvard-Universität und laut Beschreibung der meistzitierte Ernährungswissenschaftler, gestützt auf die Nurses' Health Study und die Health Professionals Follow-up Study. Behandelt würden Vollkorn versus Kartoffeln, Rindfleisch als Proteinquelle und eine Transfett-Arbeit von 1993. https://www.youtube-nocookie.com/embed/epGV9bKN6Ec 3802 2026-03-20T13:02:28.000Z 2026-10-23T01:59:45.387Z https://longevityharbor.com/en/watch/evhViOE_NHg NAD or NMN? Now that NMN is back on the market, how do you choose the right one? #nmn #nad https://i.ytimg.com/vi/evhViOE_NHg/hqdefault.jpg NAD or NMN? Now that NMN is back on the market, how do you choose the right one? #nmn #nad #antiaging #tiktokshopcreatorpicks #tiktokshopspringglowup https://www.youtube-nocookie.com/embed/evhViOE_NHg 147 2026-08-30T13:09:44.000Z 2026-10-22T19:32:37.552Z https://longevityharbor.com/de/watch/evhViOE_NHg NAD or NMN? Now that NMN is back on the market, how do you choose the right one? #nmn #nad https://i.ytimg.com/vi/evhViOE_NHg/hqdefault.jpg NAD or NMN? Now that NMN is back on the market, how do you choose the right one? #nmn #nad #antiaging #tiktokshopcreatorpicks #tiktokshopspringglowup https://www.youtube-nocookie.com/embed/evhViOE_NHg 147 2026-08-30T13:09:44.000Z 2026-10-22T19:32:37.552Z https://longevityharbor.com/en/watch/evsVcOYFKE4 Podcast description: senescent 'zombie cells' and aging research areas https://i.ytimg.com/vi/evsVcOYFKE4/hqdefault.jpg The description says Dr. Derrick Hines explains senescent cells, often called 'zombie cells,' and why researchers are increasingly interested in their role in aging, inflammation and age-related disease. https://www.youtube-nocookie.com/embed/evsVcOYFKE4 507 2026-09-29T22:17:24.000Z 2026-10-22T21:38:37.867Z https://longevityharbor.com/de/watch/evsVcOYFKE4 Podcast-Beschreibung: seneszente „Zombie-Zellen“ und Forschungsfelder zum Altern https://i.ytimg.com/vi/evsVcOYFKE4/hqdefault.jpg Laut Beschreibung erklärt Dr. Derrick Hines seneszente Zellen, oft „Zombie-Zellen“ genannt, und warum Forschende sich zunehmend für ihre Rolle bei Altern, Entzündung und altersbezogenen Erkrankungen interessieren. https://www.youtube-nocookie.com/embed/evsVcOYFKE4 507 2026-09-29T22:17:24.000Z 2026-10-22T21:38:37.867Z https://longevityharbor.com/en/watch/ewzya98bA-0 Video description asks whether aging should be viewed as a chronic disease https://i.ytimg.com/vi/ewzya98bA-0/hqdefault.jpg The description presents the creator's view that aging should be seen as a chronic disease because many of its underlying mechanisms can now be treated. It frames this as a belief, not a study result. https://www.youtube-nocookie.com/embed/ewzya98bA-0 129 2025-12-03T19:36:13.000Z 2026-10-23T03:22:30.623Z https://longevityharbor.com/de/watch/ewzya98bA-0 Videobeschreibung fragt, ob Altern als chronische Krankheit gelten sollte https://i.ytimg.com/vi/ewzya98bA-0/hqdefault.jpg Die Beschreibung gibt die Ansicht des Erstellers wieder, Altern sollte als chronische Krankheit gelten, weil viele zugrunde liegende Mechanismen heute behandelt werden können. Sie stellt dies als Überzeugung dar, nicht als Studienergebnis. https://www.youtube-nocookie.com/embed/ewzya98bA-0 129 2025-12-03T19:36:13.000Z 2026-10-23T03:22:30.623Z https://longevityharbor.com/en/watch/f1b4sxLQD08 Joan Mannick on Rapamycin Longevity Series | Turning down mTOR to young levels may be good for aging https://i.ytimg.com/vi/f1b4sxLQD08/hqdefault.jpg Dr Joan Mannick is one of the world’s leading rapamycin and mTOR researchers in the longevity field. Joan has a background in academic medicine and is currently CEO at her own company Tornado Therapeutics where they focus on developing the next generation of mTOR inhibitors. One of the company goals is to create a mTOR inhibitor which is better than Rapamycin. Throughout the years Joan has made important discoveries in humans when it comes to finding a connection between mTOR inhibition and improvement of the aging immune system. In this podcast we are going to talk about her research, drug development, mTOR, rapamycin, rapalogs and other interesting longevity topics. 00:00 Intro 01:59 Longevity interest and research 03:40 How Joan's longevity career started 06:24 What is mTOR and what makes it unique 08:55 Mechanisms underlying the effects of mTOR 10:56 How translatable is the effects of mTOR to humans 12:43 mTOR inhibition and it's upstream pathways 14:02 What is Rapamycin and how it was discovered 15:21 The weak points of Rapamycin 16:35 mTOR contains of mTORC1 and mTORC2 17:28 What is a rapalog 18:31 Detect early signs of mTORC2 inhibition 19:40 Tornado Therapeutics and it's portfolio of rapalogs 23:13 Joan proposed a courage trial to the board 27:07 Animal data show Rapamycin may improve the immune system 28:09 Designing the dosing protocol for phase 1 trial 29:26 The phase 1 trial and it's results 32:50 Aged immune system may drive aging 35:12 A good immune system may prevent cancer 36:05 Influenza and the aging immune system 38:29 The phase 2a trial and mTOR inhibition in elderly 39:32 The phase 2b and 3 trial 40:28 Antiviral genes are upregulated 42:26 Catalytic mTOR inhibitor RTB101 43:05 The phase 3 trial did not meet the primary endpoint 46:02 Pilot trial to decrease the severity 46:59 Dose protocol of Everolimus and RTB101 49:37 Safety profile between Everolimus and RTB101 52:10 Vaccines and/or mTOR inhibitor 54:51 Dosing protocol to improve the antiviral response 56:44 Taking a break or continue tak https://www.youtube-nocookie.com/embed/f1b4sxLQD08 4921 2024-01-16T23:00:20.000Z 2026-10-22T17:43:41.765Z https://longevityharbor.com/de/watch/f1b4sxLQD08 Joan Mannick on Rapamycin Longevity Series | Turning down mTOR to young levels may be good for aging https://i.ytimg.com/vi/f1b4sxLQD08/hqdefault.jpg Dr Joan Mannick is one of the world’s leading rapamycin and mTOR researchers in the longevity field. Joan has a background in academic medicine and is currently CEO at her own company Tornado Therapeutics where they focus on developing the next generation of mTOR inhibitors. One of the company goals is to create a mTOR inhibitor which is better than Rapamycin. Throughout the years Joan has made important discoveries in humans when it comes to finding a connection between mTOR inhibition and improvement of the aging immune system. In this podcast we are going to talk about her research, drug development, mTOR, rapamycin, rapalogs and other interesting longevity topics. 00:00 Intro 01:59 Longevity interest and research 03:40 How Joan's longevity career started 06:24 What is mTOR and what makes it unique 08:55 Mechanisms underlying the effects of mTOR 10:56 How translatable is the effects of mTOR to humans 12:43 mTOR inhibition and it's upstream pathways 14:02 What is Rapamycin and how it was discovered 15:21 The weak points of Rapamycin 16:35 mTOR contains of mTORC1 and mTORC2 17:28 What is a rapalog 18:31 Detect early signs of mTORC2 inhibition 19:40 Tornado Therapeutics and it's portfolio of rapalogs 23:13 Joan proposed a courage trial to the board 27:07 Animal data show Rapamycin may improve the immune system 28:09 Designing the dosing protocol for phase 1 trial 29:26 The phase 1 trial and it's results 32:50 Aged immune system may drive aging 35:12 A good immune system may prevent cancer 36:05 Influenza and the aging immune system 38:29 The phase 2a trial and mTOR inhibition in elderly 39:32 The phase 2b and 3 trial 40:28 Antiviral genes are upregulated 42:26 Catalytic mTOR inhibitor RTB101 43:05 The phase 3 trial did not meet the primary endpoint 46:02 Pilot trial to decrease the severity 46:59 Dose protocol of Everolimus and RTB101 49:37 Safety profile between Everolimus and RTB101 52:10 Vaccines and/or mTOR inhibitor 54:51 Dosing protocol to improve the antiviral response 56:44 Taking a break or continue tak https://www.youtube-nocookie.com/embed/f1b4sxLQD08 4921 2024-01-16T23:00:20.000Z 2026-10-22T17:43:41.765Z https://longevityharbor.com/en/watch/f35fzojQdss Lifespan Boost Reprogramming and Senolytics in Drosophila https://i.ytimg.com/vi/f35fzojQdss/hqdefault.jpg The original article: https://www.aging-us.com/article/204347/text Key-words: Aging, Senescence, Stem Cells, Lifespan Extension, Healthspan, Cellular Reprogramming, Yamanaka Factors, OKSM, Senolytics, Drosophila, Synergistic Interaction, Tissue Homeostasis, Senescence-Associated Secretory Phenotype (SASP), Intestinal Stem Cells (ISCs), Inflammation, Gompertz–Makeham Law of Mortality, Mortality Rate Doubling Time (MRDT), Initial Mortality Rate (A), Age-Acceleration Penalty, Mortality Compression, FOXO4-DRI Peptide, p53, FoxO Signaling, RNA-Seq, Transcriptional Profiles, Differentially Expressed Genes, Gene Ontology (GO), KEGG Pathway Enrichment, Metabolic Pathways, Cell Cycle, DNA Replication, Wnt Signaling, Hedgehog Signaling, mTOR Pathway, JAK/STAT Signaling, Epigenetic Aging Marks, Apoptosis, Tissue Repair, Organ Rejuvenation, Chronic Inflammation, Enterocytes (ECs), Enteroblasts (EBs), Senescence-Associated β-galactosidase (SA-β-gal), Ubiquitous Expression Model, ISC-Restricted Expression Model, Temperature Sensitive Expression System, Drug-Induced Expression Model, Genetically Manipulatable, Homeostasis, Cell Fate https://www.youtube-nocookie.com/embed/f35fzojQdss 802 2025-07-09T08:24:49.000Z 2026-10-22T19:43:47.701Z https://longevityharbor.com/de/watch/f35fzojQdss Lifespan Boost Reprogramming and Senolytics in Drosophila https://i.ytimg.com/vi/f35fzojQdss/hqdefault.jpg The original article: https://www.aging-us.com/article/204347/text Key-words: Aging, Senescence, Stem Cells, Lifespan Extension, Healthspan, Cellular Reprogramming, Yamanaka Factors, OKSM, Senolytics, Drosophila, Synergistic Interaction, Tissue Homeostasis, Senescence-Associated Secretory Phenotype (SASP), Intestinal Stem Cells (ISCs), Inflammation, Gompertz–Makeham Law of Mortality, Mortality Rate Doubling Time (MRDT), Initial Mortality Rate (A), Age-Acceleration Penalty, Mortality Compression, FOXO4-DRI Peptide, p53, FoxO Signaling, RNA-Seq, Transcriptional Profiles, Differentially Expressed Genes, Gene Ontology (GO), KEGG Pathway Enrichment, Metabolic Pathways, Cell Cycle, DNA Replication, Wnt Signaling, Hedgehog Signaling, mTOR Pathway, JAK/STAT Signaling, Epigenetic Aging Marks, Apoptosis, Tissue Repair, Organ Rejuvenation, Chronic Inflammation, Enterocytes (ECs), Enteroblasts (EBs), Senescence-Associated β-galactosidase (SA-β-gal), Ubiquitous Expression Model, ISC-Restricted Expression Model, Temperature Sensitive Expression System, Drug-Induced Expression Model, Genetically Manipulatable, Homeostasis, Cell Fate https://www.youtube-nocookie.com/embed/f35fzojQdss 802 2025-07-09T08:24:49.000Z 2026-10-22T19:43:47.701Z https://longevityharbor.com/en/watch/f41kTvzof8g Podcast episode: gut health, healthspan and microbiome claims https://i.ytimg.com/vi/f41kTvzof8g/hqdefault.jpg In this podcast description, Janine Barlow and Dr. Richard Day discuss gut health and healthy aging, saying longevity is really about healthspan and that microbiome thinking should start early. https://www.youtube-nocookie.com/embed/f41kTvzof8g 1566 2026-10-01T08:53:08.000Z 2026-10-22T21:33:35.879Z https://longevityharbor.com/de/watch/f41kTvzof8g Podcast-Folge: Darmgesundheit, Healthspan und Mikrobiom-Aussagen https://i.ytimg.com/vi/f41kTvzof8g/hqdefault.jpg In dieser Podcast-Beschreibung sprechen Janine Barlow und Dr. Richard Day über Darmgesundheit und gesundes Altern; sie sagen, Langlebigkeit meine eigentlich Healthspan, und man solle früh über das Mikrobiom nachdenken. https://www.youtube-nocookie.com/embed/f41kTvzof8g 1566 2026-10-01T08:53:08.000Z 2026-10-22T21:33:35.879Z https://longevityharbor.com/en/watch/fDFqEPF28FA S05E99 Should I Take Rapamycin: The Fountain of Youth or Scientific Gamble? https://i.ytimg.com/vi/fDFqEPF28FA/hqdefault.jpg Would you like to live 10, 15, or even 20 years longer just by taking a weekly pill? Join us as we dive into the buzzworthy world of rapamycin, a drug lauded by researchers as potentially the most powerful anti-aging treatment ever discovered. Dr. Rhee shares his personal journey of considering rapamycin, offering an in-depth look at its history, how it works by inhibiting the mTOR pathway, and its promising results in extending lifespan in lab animals. Beyond just living longer, these animals stayed healthier, showing delays in age-related diseases including cancer. He also discusses the current evidence in human studies, potential benefits, and noteworthy side effects like mouth sores and metabolic changes. Addressing the risks and practicalities of dosing, prescribing, and costs, Dr. Rhee reflects on why he is rapamycin-curious and the steps he might take if he began using it. Whether you're new to the topic or deeply curious about longevity science, this episode provides a comprehensive overview of rapamycin's potential to help us stay youthful longer. #Longevity #AntiAging #Rapamycin #HealthAndWellness #Biohacking #HealthyLiving #FitnessJourney #AgingGracefully #HealthyLifestyle #CrossFitLife #BotoxAndBurpees #health #movement 00:00 Introduction to Botox and Burpees 00:16 Introducing Rapamycin: The Buzz in Longevity 00:45 Personal Journey: Considering Rapamycin 01:51 Deep Dive: What is Rapamycin? 03:25 The Discovery and Medical Use of Rapamycin 05:05 Rapamycin and Longevity: The Science 08:28 Animal Studies: Rapamycin's Impact on Lifespan 11:27 Human Studies: Early Findings and Enthusiasm 16:48 Skepticism and Risks of Rapamycin 23:33 Practical Considerations: Dosing and Cost 29:28 Personal Reflection: Weighing the Pros and Cons 39:16 Conclusion and Key Takeaways https://www.youtube-nocookie.com/embed/fDFqEPF28FA 2530 2025-03-18T11:00:06.000Z 2026-10-22T18:43:08.070Z https://longevityharbor.com/de/watch/fDFqEPF28FA S05E99 Should I Take Rapamycin: The Fountain of Youth or Scientific Gamble? https://i.ytimg.com/vi/fDFqEPF28FA/hqdefault.jpg Would you like to live 10, 15, or even 20 years longer just by taking a weekly pill? Join us as we dive into the buzzworthy world of rapamycin, a drug lauded by researchers as potentially the most powerful anti-aging treatment ever discovered. Dr. Rhee shares his personal journey of considering rapamycin, offering an in-depth look at its history, how it works by inhibiting the mTOR pathway, and its promising results in extending lifespan in lab animals. Beyond just living longer, these animals stayed healthier, showing delays in age-related diseases including cancer. He also discusses the current evidence in human studies, potential benefits, and noteworthy side effects like mouth sores and metabolic changes. Addressing the risks and practicalities of dosing, prescribing, and costs, Dr. Rhee reflects on why he is rapamycin-curious and the steps he might take if he began using it. Whether you're new to the topic or deeply curious about longevity science, this episode provides a comprehensive overview of rapamycin's potential to help us stay youthful longer. #Longevity #AntiAging #Rapamycin #HealthAndWellness #Biohacking #HealthyLiving #FitnessJourney #AgingGracefully #HealthyLifestyle #CrossFitLife #BotoxAndBurpees #health #movement 00:00 Introduction to Botox and Burpees 00:16 Introducing Rapamycin: The Buzz in Longevity 00:45 Personal Journey: Considering Rapamycin 01:51 Deep Dive: What is Rapamycin? 03:25 The Discovery and Medical Use of Rapamycin 05:05 Rapamycin and Longevity: The Science 08:28 Animal Studies: Rapamycin's Impact on Lifespan 11:27 Human Studies: Early Findings and Enthusiasm 16:48 Skepticism and Risks of Rapamycin 23:33 Practical Considerations: Dosing and Cost 29:28 Personal Reflection: Weighing the Pros and Cons 39:16 Conclusion and Key Takeaways https://www.youtube-nocookie.com/embed/fDFqEPF28FA 2530 2025-03-18T11:00:06.000Z 2026-10-22T18:43:08.070Z https://longevityharbor.com/en/watch/fEc7KIAzH60 Video description: personalised nutrition instead of universal diet rules https://i.ytimg.com/vi/fEc7KIAzH60/hqdefault.jpg The description presents Ralph Steuernagel's video as arguing that no universally healthy diet exists and that nutrition should be personalised by age, stress, sex, activity and individual weak points; it also lists Dinner Cancelling and old rules such as Harahachi Bu. https://www.youtube-nocookie.com/embed/fEc7KIAzH60 1819 2025-11-27T16:01:09.000Z 2026-10-23T03:23:29.324Z https://longevityharbor.com/de/watch/fEc7KIAzH60 Videobeschreibung: persönliche Ernährung statt allgemeiner Ernährungsregeln https://i.ytimg.com/vi/fEc7KIAzH60/hqdefault.jpg Die Beschreibung stellt Ralph Steuernagels Video so dar, dass es keine universell gesunde Ernährung gebe und Ernährung nach Alter, Stress, Geschlecht, Aktivität und individuellen Schwachstellen personalisiert werden sollte; zudem nennt sie Dinner Cancelling und alte Regeln wie Harahachi Bu. https://www.youtube-nocookie.com/embed/fEc7KIAzH60 1819 2025-11-27T16:01:09.000Z 2026-10-23T03:23:29.324Z https://longevityharbor.com/en/watch/fGu2ctp46ko Video description: 5-minute routine claims to target muscle, senescent cells and mitochondria after https://i.ytimg.com/vi/fGu2ctp46ko/hqdefault.jpg The description says Dr. Victor Bennett presents three biological systems said to shape aging after 70 and a 5-minute chair routine meant to signal all three; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/fGu2ctp46ko 1469 2026-09-27T22:00:05.000Z 2026-10-22T21:43:27.072Z https://longevityharbor.com/de/watch/fGu2ctp46ko Videobeschreibung: 5-Minuten-Routine soll nach 70 auf Muskeln, seneszente Zellen und Mitochondrien w https://i.ytimg.com/vi/fGu2ctp46ko/hqdefault.jpg Laut Beschreibung stellt Dr. Victor Bennett drei biologische Systeme vor, die das Altern nach 70 prägen sollen, und eine 5-Minuten-Stuhlroutine, die alle drei ansprechen soll; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/fGu2ctp46ko 1469 2026-09-27T22:00:05.000Z 2026-10-22T21:43:27.072Z https://longevityharbor.com/en/watch/fIAM2YADBbg #118 – Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging https://i.ytimg.com/vi/fIAM2YADBbg/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Original release date: 7/6/20 Lloyd Klickstein is the Chief Science Officer at resTORbio, a biopharmaceutical company that develops medications to target the biology of aging. In this episode, Lloyd discusses his company’s clinical application of rapamycin and its derivatives. He also elucidates details of his 2014 paper—a paper that greatly influenced Peter’s perspective of rapamycin in the context of longevity. Peter and Lloyd go on to discuss the dose-dependent effect of rapamycin on immune function and compare rapamycin, fasting, and caloric restriction. We discuss: 00:00:00 - Intro 00:06:15 - His background and decision to leave academia for translational medicine 00:10:30 - Translational medicine—bridging the gap between basic science and clinical medicine 00:18:00 - What prompted Lloyd to focus on mTOR inhibition? 00:21:30 - Defining mTOR, TORC1, and TORC2, and the consequences of inhibiting them with rapamycin 00:42:15 - Dose-dependent impact of rapamycin on immune function, mTOR inhibition, and toxicity 00:53:00 - Lloyd’s 2014 experiment—mTOR inhibition improves immune function in the elderly 01:13:00 - Insights into autophagy, antigen presentation, and the pleiotropic benefits of a rapalog, and how it compares to fasting 01:18:45 - Lloyd’s 2018 experiment—TORC1 inhibition enhances immune function and reduces infections in the elderly 01:29:00 - Creation of resTORbio, subsequent studies, and takeaways about dosing, TORC2 inhibition, and tissue selectivity 01:40:00 - Comparing the longevity effect of rapamycin, fasting, and caloric restriction 01:47:00 - Excitement around RTB101—resTORbio’s mTOR inhibiting molecule 01:56:15 - Identifying rapalogs selective for TORC1 02:00:00 - Treating depression with ketamine, an activator of mTOR 02:03:30 - Epigenetic clocks, rapalogs, and metformin Show notes page: https://peterattiamd.com/lloydklickstein/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast https://www.youtube-nocookie.com/embed/fIAM2YADBbg 8095 2020-07-09T16:00:13.000Z 2026-10-22T17:43:41.091Z https://longevityharbor.com/de/watch/fIAM2YADBbg #118 – Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging https://i.ytimg.com/vi/fIAM2YADBbg/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Original release date: 7/6/20 Lloyd Klickstein is the Chief Science Officer at resTORbio, a biopharmaceutical company that develops medications to target the biology of aging. In this episode, Lloyd discusses his company’s clinical application of rapamycin and its derivatives. He also elucidates details of his 2014 paper—a paper that greatly influenced Peter’s perspective of rapamycin in the context of longevity. Peter and Lloyd go on to discuss the dose-dependent effect of rapamycin on immune function and compare rapamycin, fasting, and caloric restriction. We discuss: 00:00:00 - Intro 00:06:15 - His background and decision to leave academia for translational medicine 00:10:30 - Translational medicine—bridging the gap between basic science and clinical medicine 00:18:00 - What prompted Lloyd to focus on mTOR inhibition? 00:21:30 - Defining mTOR, TORC1, and TORC2, and the consequences of inhibiting them with rapamycin 00:42:15 - Dose-dependent impact of rapamycin on immune function, mTOR inhibition, and toxicity 00:53:00 - Lloyd’s 2014 experiment—mTOR inhibition improves immune function in the elderly 01:13:00 - Insights into autophagy, antigen presentation, and the pleiotropic benefits of a rapalog, and how it compares to fasting 01:18:45 - Lloyd’s 2018 experiment—TORC1 inhibition enhances immune function and reduces infections in the elderly 01:29:00 - Creation of resTORbio, subsequent studies, and takeaways about dosing, TORC2 inhibition, and tissue selectivity 01:40:00 - Comparing the longevity effect of rapamycin, fasting, and caloric restriction 01:47:00 - Excitement around RTB101—resTORbio’s mTOR inhibiting molecule 01:56:15 - Identifying rapalogs selective for TORC1 02:00:00 - Treating depression with ketamine, an activator of mTOR 02:03:30 - Epigenetic clocks, rapalogs, and metformin Show notes page: https://peterattiamd.com/lloydklickstein/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast https://www.youtube-nocookie.com/embed/fIAM2YADBbg 8095 2020-07-09T16:00:13.000Z 2026-10-22T17:43:41.091Z https://longevityharbor.com/en/watch/fLFo98lk4LQ Video describes epigenetic and blood-based aging clocks https://i.ytimg.com/vi/fLFo98lk4LQ/hqdefault.jpg The description says Dr. Jorge Romero explains how epigenetic (DNA) and blood-based clocks estimate biological age and the pace of aging, based on research he led at the U.S. National Institute on Aging. https://www.youtube-nocookie.com/embed/fLFo98lk4LQ 610 2026-06-16T14:50:58.000Z 2026-10-22T23:57:42.617Z https://longevityharbor.com/de/watch/fLFo98lk4LQ Video beschreibt epigenetische und blutbasierte Altersuhren https://i.ytimg.com/vi/fLFo98lk4LQ/hqdefault.jpg Laut Beschreibung erklärt Dr. Jorge Romero, wie epigenetische (DNA-) und blutbasierte Uhren das biologische Alter und das Tempo des Alterns schätzen, gestützt auf Forschung, die er am U.S. National Institute on Aging leitete. https://www.youtube-nocookie.com/embed/fLFo98lk4LQ 610 2026-06-16T14:50:58.000Z 2026-10-22T23:57:42.617Z https://longevityharbor.com/en/watch/fLZ-G3R4WQE Video description: first human partial reprogramming dose, senescent-cell map, grip strength https://i.ytimg.com/vi/fLZ-G3R4WQE/hqdefault.jpg The description reports three items: Life Biosciences gave a first human patient a partial cellular reprogramming therapy in an early-stage trial; scientists mapped senescent cells across 17 tissues; and research suggests grip strength may be partly rooted in the brain. https://www.youtube-nocookie.com/embed/fLZ-G3R4WQE 125 2026-07-05T12:11:41.000Z 2026-10-22T23:39:41.792Z https://longevityharbor.com/de/watch/fLZ-G3R4WQE Videobeschreibung: erste menschliche Teil-Reprogrammierung, Seneszenz-Zellkarte, Griffkraft https://i.ytimg.com/vi/fLZ-G3R4WQE/hqdefault.jpg Die Beschreibung berichtet über drei Punkte: Life Biosciences verabreichte einem ersten menschlichen Patienten eine partielle zelluläre Reprogrammierungstherapie in einer frühen Studie; Forschende erstellten eine Karte seneszenter Zellen über 17 Gewebe; und Forschung deutet darauf hin, dass Griffkraft teils im Gehirn begründet sein könnte. https://www.youtube-nocookie.com/embed/fLZ-G3R4WQE 125 2026-07-05T12:11:41.000Z 2026-10-22T23:39:41.792Z https://longevityharbor.com/en/watch/fLv5HeH2ff8 Top 5 Tipps zur Stärkung des Immunsystems mit Prof. Dr. Spitz https://i.ytimg.com/vi/fLv5HeH2ff8/hqdefault.jpg 1. Vitamin D ist entscheidend – mindestens 4.000 IE täglich, individuell messen & anpassen! 2. Regelmäßige Bewegung fördert das Immunsystem – nicht zu viel, aber regelmäßig aktiv sein. 3. Eine ausgewogene Ernährung mit Vitaminen (A & E) und Mineralien (Magnesium) ist notwendig für funktionierende Immunzellen. 4. Guter Schlaf (7-8 Stunden) ist unerlässlich, damit dein Körper sich regeneriert und das Immunsystem arbeitet. 5. Ein gesunder Lebensstil sorgt für ein „grünes“ Immunsystem – vermeide unnötige Stressoren und Viren-Auslöser. Optimiere deine Gesundheit durch bewussten Lifestyle! 🌱✨ #Immunsystem #VitaminD #Mikronährstoffe #Schlafqualität #WissenschaftlichBelegt https://www.youtube-nocookie.com/embed/fLv5HeH2ff8 134 2025-07-25T12:01:19.000Z 2026-10-22T20:11:49.282Z https://longevityharbor.com/de/watch/fLv5HeH2ff8 Top 5 Tipps zur Stärkung des Immunsystems mit Prof. Dr. Spitz https://i.ytimg.com/vi/fLv5HeH2ff8/hqdefault.jpg 1. Vitamin D ist entscheidend – mindestens 4.000 IE täglich, individuell messen & anpassen! 2. Regelmäßige Bewegung fördert das Immunsystem – nicht zu viel, aber regelmäßig aktiv sein. 3. Eine ausgewogene Ernährung mit Vitaminen (A & E) und Mineralien (Magnesium) ist notwendig für funktionierende Immunzellen. 4. Guter Schlaf (7-8 Stunden) ist unerlässlich, damit dein Körper sich regeneriert und das Immunsystem arbeitet. 5. Ein gesunder Lebensstil sorgt für ein „grünes“ Immunsystem – vermeide unnötige Stressoren und Viren-Auslöser. Optimiere deine Gesundheit durch bewussten Lifestyle! 🌱✨ #Immunsystem #VitaminD #Mikronährstoffe #Schlafqualität #WissenschaftlichBelegt https://www.youtube-nocookie.com/embed/fLv5HeH2ff8 134 2025-07-25T12:01:19.000Z 2026-10-22T20:11:49.282Z https://longevityharbor.com/en/watch/fMgaMM6eUsg A proposed framework for testing biological age biomarkers https://i.ytimg.com/vi/fMgaMM6eUsg/hqdefault.jpg The description presents Longevity Evidence Intelligence, a proposed framework for checking whether biological age biomarkers measure reliably, predict health outcomes and help drug-development decisions. It provides no validation results or regulatory decision. https://www.youtube-nocookie.com/embed/fMgaMM6eUsg 526 2026-10-21T04:00:36.000Z 2026-10-22T20:11:23.490Z https://longevityharbor.com/de/watch/fMgaMM6eUsg Ein vorgeschlagener Prüfrahmen für Biomarker des biologischen Alters https://i.ytimg.com/vi/fMgaMM6eUsg/hqdefault.jpg Die Beschreibung stellt Longevity Evidence Intelligence vor: einen vorgeschlagenen Rahmen zur Prüfung, ob Biomarker des biologischen Alters zuverlässig messen, Gesundheitsverläufe vorhersagen und Arzneimittelentscheidungen unterstützen. Validierungsergebnisse oder eine regulatorische Entscheidung werden nicht genannt. https://www.youtube-nocookie.com/embed/fMgaMM6eUsg 526 2026-10-21T04:00:36.000Z 2026-10-22T20:11:23.490Z https://longevityharbor.com/en/watch/fOy5ZNphs9Y Epigenetic & Glycan Age Tests Results: Are Biological Age Tests Accurate? https://i.ytimg.com/vi/fOy5ZNphs9Y/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan In this episode of the Optisan Podcast, Dr. George Sutphin discusses biological age tests, focusing on epigenetic and glycan age assessments. The conversation explores the accuracy, relevance, and implications of these tests for understanding biological versus chronological age. Key topics include the limitations of current biomarkers, the impact of lifestyle on aging metrics, and the challenges of interpreting results. The discussion emphasizes the need for caution in marketing claims and the importance of scientific validation in biological age testing. 00:00 - Intro 00:36 - Discussion on biological age tests 04:10 - Defining biomarkers of aging 07:21 - The role of epigenetics in biological aging 10:25 - Skepticism about consumer marketed tests 15:07 - Results from Dr. Sutphin's epigenetic age test 18:51 - Discussion on diet, exercise, and stress 22:30 - Emotional impact of biological age results 26:03 - Summary of organ age results from glycan age test 30:17 - Variability in test results and implications 33:08 - Exploring additional biomarkers for biological age 40:11 - Final thoughts on glycan age and epigenetic clocks 45:21 - Conclusion and takeaways from the discussion Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damag https://www.youtube-nocookie.com/embed/fOy5ZNphs9Y 3049 2024-12-05T15:00:49.000Z 2026-10-22T19:54:20.189Z https://longevityharbor.com/de/watch/fOy5ZNphs9Y Epigenetic & Glycan Age Tests Results: Are Biological Age Tests Accurate? https://i.ytimg.com/vi/fOy5ZNphs9Y/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan In this episode of the Optisan Podcast, Dr. George Sutphin discusses biological age tests, focusing on epigenetic and glycan age assessments. The conversation explores the accuracy, relevance, and implications of these tests for understanding biological versus chronological age. Key topics include the limitations of current biomarkers, the impact of lifestyle on aging metrics, and the challenges of interpreting results. The discussion emphasizes the need for caution in marketing claims and the importance of scientific validation in biological age testing. 00:00 - Intro 00:36 - Discussion on biological age tests 04:10 - Defining biomarkers of aging 07:21 - The role of epigenetics in biological aging 10:25 - Skepticism about consumer marketed tests 15:07 - Results from Dr. Sutphin's epigenetic age test 18:51 - Discussion on diet, exercise, and stress 22:30 - Emotional impact of biological age results 26:03 - Summary of organ age results from glycan age test 30:17 - Variability in test results and implications 33:08 - Exploring additional biomarkers for biological age 40:11 - Final thoughts on glycan age and epigenetic clocks 45:21 - Conclusion and takeaways from the discussion Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damag https://www.youtube-nocookie.com/embed/fOy5ZNphs9Y 3049 2024-12-05T15:00:49.000Z 2026-10-22T19:54:20.189Z https://longevityharbor.com/en/watch/fPqympdT78E Video description: five exercises proposed for strength and mobility after 50 https://i.ytimg.com/vi/fPqympdT78E/hqdefault.jpg The description presents five exercises — squats, push-ups, rows, step-ups and lunges, and loaded carries — as parts of a healthy-aging routine after 50, and stresses consistency over extreme workouts. It gives no study results. https://www.youtube-nocookie.com/embed/fPqympdT78E 730 2026-10-06T00:19:03.000Z 2026-10-22T21:18:02.208Z https://longevityharbor.com/de/watch/fPqympdT78E Videobeschreibung: fünf Übungen als Vorschlag für Kraft und Mobilität ab 50 https://i.ytimg.com/vi/fPqympdT78E/hqdefault.jpg Die Beschreibung stellt fünf Übungen — Kniebeugen, Liegestütze, Rudern, Step-Ups und Ausfallschritte sowie Tragen mit Last — als Teile einer Routine für gesundes Altern ab 50 vor und betont Beständigkeit statt extremer Workouts. Studienergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/fPqympdT78E 730 2026-10-06T00:19:03.000Z 2026-10-22T21:18:02.208Z https://longevityharbor.com/en/watch/fRhGMcH8cZA Video description: NMN as a precursor the body can use to produce NAD⁺ https://i.ytimg.com/vi/fRhGMcH8cZA/hqdefault.jpg The description says NMN is a naturally occurring molecule and a precursor the body can use to produce NAD⁺, a coenzyme involved in cellular energy metabolism. It calls NMN an interesting area of healthy-aging research. https://www.youtube-nocookie.com/embed/fRhGMcH8cZA 117 2026-09-22T22:04:13.000Z 2026-10-22T21:57:43.425Z https://longevityharbor.com/de/watch/fRhGMcH8cZA Videobeschreibung: NMN als Vorstufe, die der Körper zur NAD⁺-Bildung nutzen kann https://i.ytimg.com/vi/fRhGMcH8cZA/hqdefault.jpg Laut Beschreibung ist NMN ein natürlich vorkommendes Molekül und eine Vorstufe, die der Körper zur Bildung von NAD⁺ nutzen kann; NAD⁺ ist ein Coenzym im zellulären Energiestoffwechsel. NMN wird als interessantes Forschungsfeld der gesunden Alterung bezeichnet. https://www.youtube-nocookie.com/embed/fRhGMcH8cZA 117 2026-09-22T22:04:13.000Z 2026-10-22T21:57:43.425Z https://longevityharbor.com/en/watch/fUzztzT8psA The 10-Day Reset That Transforms Health | Dr. Mark Hyman on Functional Medicine & Longevity https://i.ytimg.com/vi/fUzztzT8psA/hqdefault.jpg What if disease isn’t random at all, but caused by everyday choices you don’t even notice? When Dr. Mark Hyman’s health collapsed, traditional medicine had no answers. Forced to find his own way, he discovered a radically different approach: functional medicine, a framework that treats the underlying causes of illness instead of just managing symptoms. Today, he is the co-founder of Function Health, the fastest-growing health company in the U.S. In this fireside chat, Dr. Hyman explains why curing cancer might only extend life by 5 years, but fixing the root causes of aging could add 30. He reveals the 7–10 day reset that’s helped thousands erase 70% of their symptoms in a single week, and why mindset, gratitude, and community may be more powerful for longevity than any pill. What you will hear • The reason modern medicine keeps us sick • Why curing cancer barely changes lifespan — but fixing aging could add decades • How functional medicine maps perfectly onto the “hallmarks of aging” • The 7 to 10-day reset that reduces symptoms by 70% • Why gratitude and purpose may be the most underrated longevity tools • Why we are getting smarter — but sicker Timestamps 00:00 – Introduction 01:10 – Entering medicine, knowing the system was broken 02:45 – Mercury poisoning & Dr. Hyman’s health collapse 04:20 – Discovering functional medicine 06:05 – Why curing cancer & heart disease barely extends life 07:15 – The hallmarks of aging & root causes of disease 10:00 – The paradox of chronic illness in modern society 12:00 – The 10-day reset that reduces symptoms by 70% 15:00 – Why disease is the body’s survival response 16:30 – How mindset, gratitude & community extend life 19:00 – Why most of us can live 100 healthy years 💬 Can functional medicine become the future of medicine? Comment YES or NO below. 📤 Share this with someone who’s still searching for answers about their health. Follow Dr. Mark Hyman • LinkedIn - https://www.linkedin.com/in/drhyman/ • Instagram – https://www.instagram.com/drmarkhyman • Explore more – https://www.youtube-nocookie.com/embed/fUzztzT8psA 1255 2025-08-21T15:28:13.000Z 2026-10-22T19:32:33.381Z https://longevityharbor.com/de/watch/fUzztzT8psA The 10-Day Reset That Transforms Health | Dr. Mark Hyman on Functional Medicine & Longevity https://i.ytimg.com/vi/fUzztzT8psA/hqdefault.jpg What if disease isn’t random at all, but caused by everyday choices you don’t even notice? When Dr. Mark Hyman’s health collapsed, traditional medicine had no answers. Forced to find his own way, he discovered a radically different approach: functional medicine, a framework that treats the underlying causes of illness instead of just managing symptoms. Today, he is the co-founder of Function Health, the fastest-growing health company in the U.S. In this fireside chat, Dr. Hyman explains why curing cancer might only extend life by 5 years, but fixing the root causes of aging could add 30. He reveals the 7–10 day reset that’s helped thousands erase 70% of their symptoms in a single week, and why mindset, gratitude, and community may be more powerful for longevity than any pill. What you will hear • The reason modern medicine keeps us sick • Why curing cancer barely changes lifespan — but fixing aging could add decades • How functional medicine maps perfectly onto the “hallmarks of aging” • The 7 to 10-day reset that reduces symptoms by 70% • Why gratitude and purpose may be the most underrated longevity tools • Why we are getting smarter — but sicker Timestamps 00:00 – Introduction 01:10 – Entering medicine, knowing the system was broken 02:45 – Mercury poisoning & Dr. Hyman’s health collapse 04:20 – Discovering functional medicine 06:05 – Why curing cancer & heart disease barely extends life 07:15 – The hallmarks of aging & root causes of disease 10:00 – The paradox of chronic illness in modern society 12:00 – The 10-day reset that reduces symptoms by 70% 15:00 – Why disease is the body’s survival response 16:30 – How mindset, gratitude & community extend life 19:00 – Why most of us can live 100 healthy years 💬 Can functional medicine become the future of medicine? Comment YES or NO below. 📤 Share this with someone who’s still searching for answers about their health. Follow Dr. Mark Hyman • LinkedIn - https://www.linkedin.com/in/drhyman/ • Instagram – https://www.instagram.com/drmarkhyman • Explore more – https://www.youtube-nocookie.com/embed/fUzztzT8psA 1255 2025-08-21T15:28:13.000Z 2026-10-22T19:32:33.381Z https://longevityharbor.com/en/watch/fVJY6r912rk Toren Finkel at ARDD2023: Developing small molecule therapy targeting the hallmarks of aging https://i.ytimg.com/vi/fVJY6r912rk/hqdefault.jpg Toren Finkel , University of Pittsburgh School of Medicine, USA presents at the 10th Aging Research and Drug Discovery conference: Developing small molecule therapy targeting the hallmarks of aging. https://www.youtube-nocookie.com/embed/fVJY6r912rk 1406 2023-10-30T18:54:45.000Z 2026-10-22T19:21:23.230Z https://longevityharbor.com/de/watch/fVJY6r912rk Toren Finkel at ARDD2023: Developing small molecule therapy targeting the hallmarks of aging https://i.ytimg.com/vi/fVJY6r912rk/hqdefault.jpg Toren Finkel , University of Pittsburgh School of Medicine, USA presents at the 10th Aging Research and Drug Discovery conference: Developing small molecule therapy targeting the hallmarks of aging. https://www.youtube-nocookie.com/embed/fVJY6r912rk 1406 2023-10-30T18:54:45.000Z 2026-10-22T19:21:23.230Z https://longevityharbor.com/en/watch/fYAEINPokKw Longevity Supplement EP.5 Vitamins effects on Hallmarks of aging for Longevity https://i.ytimg.com/vi/fYAEINPokKw/hqdefault.jpg วิตามินหลายชนิด มีผลต่อการชะลอความเสื่อมในระดับเซลล์ วันนี้มาเล่ากลไกการทำงานของวิตามินแต่ละตัวที่มีผลต่อ Hallmarks of aging ทำให้รู้ว่าตัวไหนมีความจำเป็นควรจะได้รับอย่างเพียงพอ เพื่อให้การทำงานของเซลล์ทำงานได้ดี ส่งผลถึงการทำงานของเซลล์และอวัยวะ ลดความเสื่อมของอวัยวะ และป้องกันการเกิดโรคเรื้อรังต่าง ๆ #hallmarksofaging #theLongevist #Longevity #Longevitysupplement #supplement #หมออั๋น https://www.youtube-nocookie.com/embed/fYAEINPokKw 3074 2024-01-15T03:27:52.000Z 2026-10-22T19:32:33.387Z https://longevityharbor.com/de/watch/fYAEINPokKw Longevity Supplement EP.5 Vitamins effects on Hallmarks of aging for Longevity https://i.ytimg.com/vi/fYAEINPokKw/hqdefault.jpg วิตามินหลายชนิด มีผลต่อการชะลอความเสื่อมในระดับเซลล์ วันนี้มาเล่ากลไกการทำงานของวิตามินแต่ละตัวที่มีผลต่อ Hallmarks of aging ทำให้รู้ว่าตัวไหนมีความจำเป็นควรจะได้รับอย่างเพียงพอ เพื่อให้การทำงานของเซลล์ทำงานได้ดี ส่งผลถึงการทำงานของเซลล์และอวัยวะ ลดความเสื่อมของอวัยวะ และป้องกันการเกิดโรคเรื้อรังต่าง ๆ #hallmarksofaging #theLongevist #Longevity #Longevitysupplement #supplement #หมออั๋น https://www.youtube-nocookie.com/embed/fYAEINPokKw 3074 2024-01-15T03:27:52.000Z 2026-10-22T19:32:33.387Z https://longevityharbor.com/en/watch/fYVB8_kFAwA Senolytics for skin ageing: what a video description claims and leaves open https://i.ytimg.com/vi/fYVB8_kFAwA/hqdefault.jpg The description presents senolytics as compounds studied to remove senescent cells, links these cells to skin ageing and inflammation, and says human research is still developing. It attributes laboratory results to lab models and notes that not all marketed anti-ageing products share the same scientific backing. https://www.youtube-nocookie.com/embed/fYVB8_kFAwA 260 2026-02-14T17:00:57.000Z 2026-10-23T02:34:01.323Z https://longevityharbor.com/de/watch/fYVB8_kFAwA Senolytika gegen Hautalterung: Was eine Videobeschreibung behauptet und offen lässt https://i.ytimg.com/vi/fYVB8_kFAwA/hqdefault.jpg Die Beschreibung stellt Senolytika als untersuchte Verbindungen vor, die seneszente Zellen entfernen sollen, verknüpft diese Zellen mit Hautalterung und Entzündung und betont, dass die Forschung am Menschen noch in Entwicklung ist. Laborergebnisse werden Labor-Modellen zugeschrieben; nicht alle vermarkteten Anti-Aging-Produkte hätten dieselbe wissenschaftliche Grundlage. https://www.youtube-nocookie.com/embed/fYVB8_kFAwA 260 2026-02-14T17:00:57.000Z 2026-10-23T02:34:01.323Z https://longevityharbor.com/en/watch/fcXxI_htZS0 Food for Thought: The Role of Nutrition in Healthy Aging https://i.ytimg.com/vi/fcXxI_htZS0/hqdefault.jpg The way we eat throughout our lives impacts the way we age. Science has proven that a well-balanced and varied diet full of nutritious foods like fruits and veggies, whole grains, legumes, nuts, and lean proteins; and limited in sugar, salt, saturated or solid fats, and alcoholic beverages; is critical to good health. This means we all have the power to maximize and improve our health, add vitality to our years, reduce the risk of disease, and increase our healthspans—the number of years we live in good health. And research shows that it’s never too late to make improvements. Without proper nutrition our bodies can’t stay healthy, fight off disease, or deal with illnesses that we already have. Poor nutrition weakens our immune systems and leaves us vulnerable to infections, and slower recovery and wound healing. It also causes unhealthy weight changes and muscle loss that can lead to frailty, falls, broken bones, disability, loss of independence, and disease complications. It can also lead to nutrition-related diseases and conditions. The latest Dietary Guidelines from the U.S. Department of Agriculture, address nutrition at various life stages and provide important recommendations on achieving a well-rounded diet. The guidelines emphasize that the foods and beverages we consume have a profound impact on our health—now and in the years to come—but MOST Americans don’t follow a healthy dietary pattern. They also highlight the fact that our nutrition decisions add up “bite by bite” and are important at every age. Also available in Spanish at https://www.youtube.com/watch?v=GGZmwN0kEqU and with closed captioning at https://www.youtube.com/watch?v=wFYXd7Q0aUU. https://www.youtube-nocookie.com/embed/fcXxI_htZS0 391 2021-05-04T17:37:31.000Z 2026-10-23T01:53:57.088Z https://longevityharbor.com/de/watch/fcXxI_htZS0 Food for Thought: The Role of Nutrition in Healthy Aging https://i.ytimg.com/vi/fcXxI_htZS0/hqdefault.jpg The way we eat throughout our lives impacts the way we age. Science has proven that a well-balanced and varied diet full of nutritious foods like fruits and veggies, whole grains, legumes, nuts, and lean proteins; and limited in sugar, salt, saturated or solid fats, and alcoholic beverages; is critical to good health. This means we all have the power to maximize and improve our health, add vitality to our years, reduce the risk of disease, and increase our healthspans—the number of years we live in good health. And research shows that it’s never too late to make improvements. Without proper nutrition our bodies can’t stay healthy, fight off disease, or deal with illnesses that we already have. Poor nutrition weakens our immune systems and leaves us vulnerable to infections, and slower recovery and wound healing. It also causes unhealthy weight changes and muscle loss that can lead to frailty, falls, broken bones, disability, loss of independence, and disease complications. It can also lead to nutrition-related diseases and conditions. The latest Dietary Guidelines from the U.S. Department of Agriculture, address nutrition at various life stages and provide important recommendations on achieving a well-rounded diet. The guidelines emphasize that the foods and beverages we consume have a profound impact on our health—now and in the years to come—but MOST Americans don’t follow a healthy dietary pattern. They also highlight the fact that our nutrition decisions add up “bite by bite” and are important at every age. Also available in Spanish at https://www.youtube.com/watch?v=GGZmwN0kEqU and with closed captioning at https://www.youtube.com/watch?v=wFYXd7Q0aUU. https://www.youtube-nocookie.com/embed/fcXxI_htZS0 391 2021-05-04T17:37:31.000Z 2026-10-23T01:53:57.088Z https://longevityharbor.com/en/watch/fhjTfEDdkoA Fall 2019 Grant Award: Investigation of Rapamycin as a Therapeutic Option https://i.ytimg.com/vi/fhjTfEDdkoA/hqdefault.jpg In this short video, Dr. Theresa Strong explains the rationale behind funding Dr. Schaaf's study: Investigation of Rapamycin as a Therapeutic Option in a Mouse Model of Schaaf-Yang Syndrome (SYS). In a mouse model of PWS and SYS, and in neurons generated from skin fibroblasts of individuals with SYS, Dr. Schaaf’s has discovered a marked upregulation of the ‘mTOR’ pathway, a pathway that is important for many cellular processes. Importantly, there are known drugs that can reduce the activity of the pathway. Schaaf will investigate whether one of these drugs, rapamycin, has a positive impact on cellular and mouse models of SYS. https://www.youtube-nocookie.com/embed/fhjTfEDdkoA 159 2019-11-06T22:50:17.000Z 2026-10-22T17:43:41.779Z https://longevityharbor.com/de/watch/fhjTfEDdkoA Fall 2019 Grant Award: Investigation of Rapamycin as a Therapeutic Option https://i.ytimg.com/vi/fhjTfEDdkoA/hqdefault.jpg In this short video, Dr. Theresa Strong explains the rationale behind funding Dr. Schaaf's study: Investigation of Rapamycin as a Therapeutic Option in a Mouse Model of Schaaf-Yang Syndrome (SYS). In a mouse model of PWS and SYS, and in neurons generated from skin fibroblasts of individuals with SYS, Dr. Schaaf’s has discovered a marked upregulation of the ‘mTOR’ pathway, a pathway that is important for many cellular processes. Importantly, there are known drugs that can reduce the activity of the pathway. Schaaf will investigate whether one of these drugs, rapamycin, has a positive impact on cellular and mouse models of SYS. https://www.youtube-nocookie.com/embed/fhjTfEDdkoA 159 2019-11-06T22:50:17.000Z 2026-10-22T17:43:41.779Z https://longevityharbor.com/en/watch/fkRqBBsxHjY 5 Exercises TO SLOW DOWN AGING (Backed by Research!) https://i.ytimg.com/vi/fkRqBBsxHjY/hqdefault.jpg Want to look younger, feel stronger, and boost your energy—all while reversing the effects of aging? In this video, we reveal the ONLY 5 exercises that science has proven to slow down and even reverse aging. Backed by peer-reviewed studies, these exercises target longevity, cellular health, and strength—without needing a gym membership! - Backed by real research - Easy to follow - Suitable for all ages Stay young. Stay strong. Start your transformation today! 💪 Don’t forget to LIKE, SUBSCRIBE, and hit the BELL 🔔 for more science-backed health tips. #reverse aging #anti aging exercises #science backed workouts #exercises to look younger #longevity exercises #slow aging #stay young #proven exercises #fitness over 40 #science of aging #health and longevity #how to reverse aging #youthful body #anti-aging routine #best exercises for aging #age reversal workout #cellular health #exercise for longevity https://www.youtube-nocookie.com/embed/fkRqBBsxHjY 801 2025-06-26T16:30:20.000Z 2026-10-22T18:32:08.296Z https://longevityharbor.com/de/watch/fkRqBBsxHjY 5 Exercises TO SLOW DOWN AGING (Backed by Research!) https://i.ytimg.com/vi/fkRqBBsxHjY/hqdefault.jpg Want to look younger, feel stronger, and boost your energy—all while reversing the effects of aging? In this video, we reveal the ONLY 5 exercises that science has proven to slow down and even reverse aging. Backed by peer-reviewed studies, these exercises target longevity, cellular health, and strength—without needing a gym membership! - Backed by real research - Easy to follow - Suitable for all ages Stay young. Stay strong. Start your transformation today! 💪 Don’t forget to LIKE, SUBSCRIBE, and hit the BELL 🔔 for more science-backed health tips. #reverse aging #anti aging exercises #science backed workouts #exercises to look younger #longevity exercises #slow aging #stay young #proven exercises #fitness over 40 #science of aging #health and longevity #how to reverse aging #youthful body #anti-aging routine #best exercises for aging #age reversal workout #cellular health #exercise for longevity https://www.youtube-nocookie.com/embed/fkRqBBsxHjY 801 2025-06-26T16:30:20.000Z 2026-10-22T18:32:08.296Z https://longevityharbor.com/en/watch/fnvHAqpMxjQ Video description: aging biology, brain changes and longevity research https://i.ytimg.com/vi/fnvHAqpMxjQ/hqdefault.jpg The description says this documentary episode covers why aging happens, cellular changes, brain and memory changes, genetics, lifestyle and environment, and what science currently knows about longevity. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/fnvHAqpMxjQ 544 2026-08-10T12:09:19.000Z 2026-10-22T23:06:39.317Z https://longevityharbor.com/de/watch/fnvHAqpMxjQ Videobeschreibung: Alternsbiologie, Hirnveränderungen und Langlebigkeitsforschung https://i.ytimg.com/vi/fnvHAqpMxjQ/hqdefault.jpg Laut Beschreibung behandelt diese Dokumentarfolge, warum Altern geschieht, zelluläre Veränderungen, Veränderungen von Gehirn und Gedächtnis, Genetik, Lebensstil und Umwelt sowie das aktuelle Wissen zur Langlebigkeit. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/fnvHAqpMxjQ 544 2026-08-10T12:09:19.000Z 2026-10-22T23:06:39.317Z https://longevityharbor.com/en/watch/fpfDsDGbuyI Video description: epigenetic clocks and DNA methylation as age estimates https://i.ytimg.com/vi/fpfDsDGbuyI/hqdefault.jpg The description says the video explains how chemical marks on DNA, called DNA methylation, allow epigenetic clocks to estimate chronological age and offer insights into biological aging. https://www.youtube-nocookie.com/embed/fpfDsDGbuyI 733 2026-07-01T15:21:30.000Z 2026-10-22T23:41:51.816Z https://longevityharbor.com/de/watch/fpfDsDGbuyI Videobeschreibung: epigenetische Uhren und DNA-Methylierung als Altersschätzung https://i.ytimg.com/vi/fpfDsDGbuyI/hqdefault.jpg Laut Beschreibung erklärt das Video, wie chemische Markierungen auf der DNA, DNA-Methylierung genannt, epigenetischen Uhren Schätzungen des chronologischen Alters ermöglichen und Einblicke in biologisches Altern geben. https://www.youtube-nocookie.com/embed/fpfDsDGbuyI 733 2026-07-01T15:21:30.000Z 2026-10-22T23:41:51.816Z https://longevityharbor.com/en/watch/fsB0qKbLDCY Video description: David Sinclair podcast summary with supplements, fasting, exercise and hormesis https://i.ytimg.com/vi/fsB0qKbLDCY/hqdefault.jpg The description says the video summarizes David Sinclair's current supplement routine, updates from three new interviews and the first episode of the new Lifespan podcast season, plus tips the creator says could add years or decades of healthy life. The description itself gives no study results. https://www.youtube-nocookie.com/embed/fsB0qKbLDCY 1354 2026-05-12T15:45:04.000Z 2026-10-23T01:06:46.418Z https://longevityharbor.com/de/watch/fsB0qKbLDCY Videobeschreibung: David-Sinclair-Podcast-Zusammenfassung zu Supplements, Fasten, Sport und Hormesis https://i.ytimg.com/vi/fsB0qKbLDCY/hqdefault.jpg Laut Beschreibung fasst das Video David Sinclairs aktuelle Supplement-Routine, Updates aus drei neuen Interviews und die erste Folge der neuen Lifespan-Podcast-Staffel zusammen, dazu Tipps, die laut Erstellerin Jahre oder Jahrzehnte gesunder Lebenszeit bringen könnten. Die Beschreibung selbst nennt keine Studienergebnisse. https://www.youtube-nocookie.com/embed/fsB0qKbLDCY 1354 2026-05-12T15:45:04.000Z 2026-10-23T01:06:46.418Z https://longevityharbor.com/en/watch/fvO8e-2y37k The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle https://i.ytimg.com/vi/fvO8e-2y37k/hqdefault.jpg Protein is far more than a building block for muscle—it’s essential for metabolic health, insulin sensitivity, and preventing conditions like type 2 diabetes and sarcopenia. But how much do we truly need? And could too much protein, especially from meat, actually be harmful? This episode challenges the conventional RDA of 0.8 g/kg, presenting research that supports higher intakes of 1.2–2 g/kg for maintaining muscle, improving body composition, and promoting longevity. We also confront myths around protein timing and the so-called "anabolic window.” Lastly, we address concerns about protein’s links to cancer, heart disease, and kidney function, showing how exercise can redirect growth factors like IGF-1 to promote repair while mitigating risks. Download my “How to Train According to the Experts” guide—your go-to resource for distilled advice on training, nutrition, and supplementation from nearly 100 episodes of this show: https://howtotrainguide.com/ CHAPTERS: 00:00:00 Introduction 00:02:47 Why muscle matters 00:05:12 Why do we lose muscle? 00:06:46 How to negate anabolic resistance 00:07:39 Why it's never too late to build muscle 00:08:20 Requirements for overweight & obese individuals 00:09:07 Exposing the flaws of the RDA 00:10:27 Optimal intake when resistance training 00:11:10 What to do when losing weight 00:12:24 Does protein harm healthy kidneys? 00:14:14 How important is distribution? 00:16:27 Debunking the "anabolic window" 00:18:04 Benefits of pre-sleep intake 00:19:36 Timing & distribution takeaways 00:20:17 What are the best sources? 00:23:22 Animal vs. plant protein 00:25:44 Protein supplements (whey, casein, & collagen) 00:27:14 Does high intake accelerate aging? 00:30:49 Why exercise changes the story 00:33:19 What we can learn from athletes 00:33:54 Does high intake accelerate atherosclerosis? 00:36:08 8 key takeaways EPISODE LINKS: Show notes & transcript: https://www.foundmyfitness.com/episodes/protein PODCAST INFO: Apple Podcasts: https://podcasts.apple.com/us/podcast/097-the-science-of https://www.youtube-nocookie.com/embed/fvO8e-2y37k 2410 2024-12-05T16:30:06.000Z 2026-10-22T18:43:11.818Z https://longevityharbor.com/de/watch/fvO8e-2y37k The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle https://i.ytimg.com/vi/fvO8e-2y37k/hqdefault.jpg Protein is far more than a building block for muscle—it’s essential for metabolic health, insulin sensitivity, and preventing conditions like type 2 diabetes and sarcopenia. But how much do we truly need? And could too much protein, especially from meat, actually be harmful? This episode challenges the conventional RDA of 0.8 g/kg, presenting research that supports higher intakes of 1.2–2 g/kg for maintaining muscle, improving body composition, and promoting longevity. We also confront myths around protein timing and the so-called "anabolic window.” Lastly, we address concerns about protein’s links to cancer, heart disease, and kidney function, showing how exercise can redirect growth factors like IGF-1 to promote repair while mitigating risks. Download my “How to Train According to the Experts” guide—your go-to resource for distilled advice on training, nutrition, and supplementation from nearly 100 episodes of this show: https://howtotrainguide.com/ CHAPTERS: 00:00:00 Introduction 00:02:47 Why muscle matters 00:05:12 Why do we lose muscle? 00:06:46 How to negate anabolic resistance 00:07:39 Why it's never too late to build muscle 00:08:20 Requirements for overweight & obese individuals 00:09:07 Exposing the flaws of the RDA 00:10:27 Optimal intake when resistance training 00:11:10 What to do when losing weight 00:12:24 Does protein harm healthy kidneys? 00:14:14 How important is distribution? 00:16:27 Debunking the "anabolic window" 00:18:04 Benefits of pre-sleep intake 00:19:36 Timing & distribution takeaways 00:20:17 What are the best sources? 00:23:22 Animal vs. plant protein 00:25:44 Protein supplements (whey, casein, & collagen) 00:27:14 Does high intake accelerate aging? 00:30:49 Why exercise changes the story 00:33:19 What we can learn from athletes 00:33:54 Does high intake accelerate atherosclerosis? 00:36:08 8 key takeaways EPISODE LINKS: Show notes & transcript: https://www.foundmyfitness.com/episodes/protein PODCAST INFO: Apple Podcasts: https://podcasts.apple.com/us/podcast/097-the-science-of https://www.youtube-nocookie.com/embed/fvO8e-2y37k 2410 2024-12-05T16:30:06.000Z 2026-10-22T18:43:11.818Z https://longevityharbor.com/en/watch/fvwtn059WLY Fasting and the Brain: The Latest Research With Dr. Valter Longo | Live Talk Being Patient https://i.ytimg.com/vi/fvwtn059WLY/hqdefault.jpg Dr. Valter Longo of the University of Southern California returns to Live Talks to discuss his research on fasting and brain health. In his previous Live Talk with Being Patient, Longo discussed how fasting could be the most potent way to activate rejuvenation processes in the body and lower the risk of disease. Longo is internationally recognized as a leader in the field of aging studies and related diseases. His discoveries include some of the major genetic pathways that regulate aging and life-threatening diseases and the identification of a genetic mutation that protects men from several common diseases. He has pioneered the studies of prolonged fasting and fasting mimicking diet and discovered their effect on multi-system stem cell activation and regeneration, leading to clinical trials on cancer, Alzheimer’s disease, diabetes, cardiovascular disease and autoimmunities. His book, The Longevity Diet, is an international bestseller, translated in over 15 languages and sold in more than 20 countries around the globe. https://www.youtube-nocookie.com/embed/fvwtn059WLY 2582 2024-02-27T07:38:01.000Z 2026-10-22T19:32:32.019Z https://longevityharbor.com/de/watch/fvwtn059WLY Fasting and the Brain: The Latest Research With Dr. Valter Longo | Live Talk Being Patient https://i.ytimg.com/vi/fvwtn059WLY/hqdefault.jpg Dr. Valter Longo of the University of Southern California returns to Live Talks to discuss his research on fasting and brain health. In his previous Live Talk with Being Patient, Longo discussed how fasting could be the most potent way to activate rejuvenation processes in the body and lower the risk of disease. Longo is internationally recognized as a leader in the field of aging studies and related diseases. His discoveries include some of the major genetic pathways that regulate aging and life-threatening diseases and the identification of a genetic mutation that protects men from several common diseases. He has pioneered the studies of prolonged fasting and fasting mimicking diet and discovered their effect on multi-system stem cell activation and regeneration, leading to clinical trials on cancer, Alzheimer’s disease, diabetes, cardiovascular disease and autoimmunities. His book, The Longevity Diet, is an international bestseller, translated in over 15 languages and sold in more than 20 countries around the globe. https://www.youtube-nocookie.com/embed/fvwtn059WLY 2582 2024-02-27T07:38:01.000Z 2026-10-22T19:32:32.019Z https://longevityharbor.com/en/watch/fzxGgabL6q4 Doctor's video description on the January 2026 US dietary guidelines and a reversed food pyramid https://i.ytimg.com/vi/fzxGgabL6q4/hqdefault.jpg In the description, Dr. Lutz Graumann says he will classify the new US dietary guidelines from early January 2026 medically: real food instead of ultra-processed products, less sugar, refined carbohydrates and snacking, and protein at 1.2–1.6 g per kg body weight per day for satiety, metabolism and muscle mass. https://www.youtube-nocookie.com/embed/fzxGgabL6q4 652 2026-01-25T09:00:53.000Z 2026-10-23T02:46:11.589Z https://longevityharbor.com/de/watch/fzxGgabL6q4 Arzt-Videobeschreibung zu den neuen US-Ernährungsleitlinien von Januar 2026 und einer umgedrehten Er https://i.ytimg.com/vi/fzxGgabL6q4/hqdefault.jpg In der Beschreibung kündigt Dr. Lutz Graumann an, die neuen US-Ernährungsleitlinien von Anfang Januar 2026 ärztlich einzuordnen: echte Lebensmittel statt ultraverarbeiteter Produkte, weniger Zucker, raffinierte Kohlenhydrate und Snacking sowie Protein mit 1,2–1,6 g pro kg Körpergewicht pro Tag für Sättigung, Stoffwechsel und Muskelmasse. https://www.youtube-nocookie.com/embed/fzxGgabL6q4 652 2026-01-25T09:00:53.000Z 2026-10-23T02:46:11.589Z https://longevityharbor.com/en/watch/g4-RftOrGC4 Rapamycin and longevity: mouse data, sex-specific findings and the human evidence gap https://i.ytimg.com/vi/g4-RftOrGC4/hqdefault.jpg The description says rapamycin blocks mTOR and triggers autophagy, that animal lifespan studies exist, and that sex-specific findings and a human trial data gap matter; it presents no human lifespan results. https://www.youtube-nocookie.com/embed/g4-RftOrGC4 404 2026-10-04T19:00:28.000Z 2026-10-22T21:23:05.436Z https://longevityharbor.com/de/watch/g4-RftOrGC4 Rapamycin und Langlebigkeit: Mausdaten, geschlechtsspezifische Befunde und die Lücke beim Menschen https://i.ytimg.com/vi/g4-RftOrGC4/hqdefault.jpg Die Beschreibung sagt, Rapamycin blockiere mTOR und löse Autophagie aus, es gebe Tier-Lebensspannenstudien, und geschlechtsspezifische Befunde sowie eine Datenlücke bei Humanstudien seien wichtig; menschliche Lebensspannenergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/g4-RftOrGC4 404 2026-10-04T19:00:28.000Z 2026-10-22T21:23:05.436Z https://longevityharbor.com/en/watch/g5eH2SV3qBM Anti-Aging-Medikamente: Können Rapamycin und Co das Altern bremsen? | ARD GESUND https://i.ytimg.com/vi/g5eH2SV3qBM/hqdefault.jpg Was gibt es Neues aus der Alternsforschung? Können Metformin, Rapamycin oder Senolytika, bereits zugelassene Medikamente, unser Leben verlängern? Welche Rolle spielen unsere Gene und was hilft wirklich, wenn wir lange leben wollen? 00:00 - Wie weit ist die Alternsforschung? 00:45 - Prof. Christoph Englert, Molekulargenetiker: Altern ist ein komplexer Prozess 01:12 - Dr. Sebastian Grönke, Molekularbiologe: Unsterblichkeit ist unrealistisch 01:47 - Welche Rolle spielen unsere Gene? 02:25 - Warum bleiben wir nicht länger fit und jung? 03:04 - Forschung am Killifisch 03:25 - Äußere Einflüsse schaden dem Erbgut 03:55 - Senolytika töten Zombie-Zellen ab 04:38 - Rapamycin verlängert das Leben bei Mäusen 05:18 - Dr. Dan Ehninger, Neurowissenschaftler: Altern an sich wird nicht beeinflusst 05:51 - Dr. Maria Ermolaeva, Molekularbiologin, warnt vor Metformin 06:44 - Durchbruch lässt noch auf sich warten Ein Beitrag des Bayerischen Rundfunk. #AntiAging #Rapamycin #BR. Foto-Credit: picture alliance / Zoonar | Ziga Plahutar https://www.youtube-nocookie.com/embed/g5eH2SV3qBM 418 2023-05-13T16:01:15.000Z 2026-10-22T17:43:41.043Z https://longevityharbor.com/de/watch/g5eH2SV3qBM Anti-Aging-Medikamente: Können Rapamycin und Co das Altern bremsen? | ARD GESUND https://i.ytimg.com/vi/g5eH2SV3qBM/hqdefault.jpg Was gibt es Neues aus der Alternsforschung? Können Metformin, Rapamycin oder Senolytika, bereits zugelassene Medikamente, unser Leben verlängern? Welche Rolle spielen unsere Gene und was hilft wirklich, wenn wir lange leben wollen? 00:00 - Wie weit ist die Alternsforschung? 00:45 - Prof. Christoph Englert, Molekulargenetiker: Altern ist ein komplexer Prozess 01:12 - Dr. Sebastian Grönke, Molekularbiologe: Unsterblichkeit ist unrealistisch 01:47 - Welche Rolle spielen unsere Gene? 02:25 - Warum bleiben wir nicht länger fit und jung? 03:04 - Forschung am Killifisch 03:25 - Äußere Einflüsse schaden dem Erbgut 03:55 - Senolytika töten Zombie-Zellen ab 04:38 - Rapamycin verlängert das Leben bei Mäusen 05:18 - Dr. Dan Ehninger, Neurowissenschaftler: Altern an sich wird nicht beeinflusst 05:51 - Dr. Maria Ermolaeva, Molekularbiologin, warnt vor Metformin 06:44 - Durchbruch lässt noch auf sich warten Ein Beitrag des Bayerischen Rundfunk. #AntiAging #Rapamycin #BR. Foto-Credit: picture alliance / Zoonar | Ziga Plahutar https://www.youtube-nocookie.com/embed/g5eH2SV3qBM 418 2023-05-13T16:01:15.000Z 2026-10-22T17:43:41.043Z https://longevityharbor.com/en/watch/g6AV55THcxA XPRIZE Healthspan: Jamie Justice on functional aging metrics and a $101 million race https://i.ytimg.com/vi/g6AV55THcxA/hqdefault.jpg In this video description, XPRIZE Healthspan Executive Director Jamie Justice tells Brianna Stubbs about a $101 million competition aiming to restore 10 years of muscle, cognitive and immune function within one year, and about moving beyond binary alive-or-dead measures toward functional independence. https://www.youtube-nocookie.com/embed/g6AV55THcxA 2127 2026-02-18T13:26:07.000Z 2026-10-23T02:28:10.617Z https://longevityharbor.com/de/watch/g6AV55THcxA XPRIZE Healthspan: Jamie Justice über funktionale Alternsmaße und ein Rennen um 101 Millionen Dollar https://i.ytimg.com/vi/g6AV55THcxA/hqdefault.jpg In dieser Videobeschreibung spricht XPRIZE-Healthspan-Direktorin Jamie Justice mit Brianna Stubbs über einen Wettbewerb über 101 Millionen Dollar, der 10 Jahre Muskel-, kognitive und Immunfunktion innerhalb eines Jahres wiederherstellen soll, und über den Weg weg von binären Lebend-oder-tot-Maßen hin zur funktionalen Selbstständigkeit. https://www.youtube-nocookie.com/embed/g6AV55THcxA 2127 2026-02-18T13:26:07.000Z 2026-10-23T02:28:10.617Z https://longevityharbor.com/en/watch/g7RUaiEAbhU Video description: geroscience, 12 hallmarks of aging and proposed anti-aging drugs https://i.ytimg.com/vi/g7RUaiEAbhU/hqdefault.jpg The description presents geroscience as a shift from treating disease to predicting and preventing it, and outlines the 12 hallmarks of aging plus drugs and lifestyle approaches being tested to slow aging. https://www.youtube-nocookie.com/embed/g7RUaiEAbhU 463 2026-05-06T08:49:09.000Z 2026-10-23T01:18:58.888Z https://longevityharbor.com/de/watch/g7RUaiEAbhU Videobeschreibung: Geroscience, 12 Hallmarks des Alterns und vorgeschlagene Anti-Aging-Medikamente https://i.ytimg.com/vi/g7RUaiEAbhU/hqdefault.jpg Die Beschreibung stellt Geroscience als Wandel vom Behandeln von Krankheiten zum Vorhersagen und Vorbeugen dar und skizziert die 12 Hallmarks des Alterns sowie getestete Medikamente und Lebensstilansätze zur Verlangsamung des Alterns. https://www.youtube-nocookie.com/embed/g7RUaiEAbhU 463 2026-05-06T08:49:09.000Z 2026-10-23T01:18:58.888Z https://longevityharbor.com/en/watch/g8zvOcKsYPw Physician video: exercise, fasting and supplement habits may add stress https://i.ytimg.com/vi/g8zvOcKsYPw/hqdefault.jpg In the description, Dr. Shayna Peter says exercise, intermittent fasting and supplements can support healthy aging, but routines not matched to individual physiology may add stress rather than resilience. https://www.youtube-nocookie.com/embed/g8zvOcKsYPw 107 2026-09-25T17:20:25.000Z 2026-10-22T21:48:54.434Z https://longevityharbor.com/de/watch/g8zvOcKsYPw Ärztliches Video: Sport-, Fasten- und Supplement-Routinen können Stress erzeugen https://i.ytimg.com/vi/g8zvOcKsYPw/hqdefault.jpg In der Beschreibung sagt Dr. Shayna Peter, Sport, Intervallfasten und Supplements können gesundes Altern unterstützen; nicht zur individuellen Physiologie passende Routinen könnten jedoch eher Stress als Resilienz erzeugen. https://www.youtube-nocookie.com/embed/g8zvOcKsYPw 107 2026-09-25T17:20:25.000Z 2026-10-22T21:48:54.434Z https://longevityharbor.com/en/watch/g9NSzrjrc6w ภาวะเหนือพันธุกรรม Epigenetic คืออะไร วางแผนอายุยืน เริ่มต้นที่การตรวจประเมินความแก่ชรา https://i.ytimg.com/vi/g9NSzrjrc6w/hqdefault.jpg ภาวะเหนือพันธุกรรม (Epigenetic) คือ การเปลี่ยนแปลงของสิ่งมีชีวิตที่ได้รับมาจากพ่อ-แม่ โดยที่ไม่ได้มีการเปลี่ยนแปลงจากลำดับเบส ช่วยให้เราได้ทราบถึงการเกิดความชรา ซึ่งในปัจจุบันเราสามารถตรวจดู Epigenetic ได้ และนำไปสู่การปรับวิธีการใช้ชีวิต เพื่อให้เรามีสุขภาพที่ดีและมีคุณภาพชีวิตที่ยืนยาว ขอขอบคุณข้อมูลจาก นพ.วิทูร จุลรัตนาภรณ์ อายุแพทย์โรคหัวใจและแพทย์ผู้ดูแลด้านเวชศาสตร์ชะลอวัย . 0:23 ภาวะเหนือพันธุกรรม #Epigenetic คืออะไร ? 1:06 #ภาวะเหนือพันธุกรรม มีหลายกลไก อะไรบ้าง ? 1:59 Epigenetic มีประโยชน์อย่างไร ตรวจได้อย่างไร และ ผลการตรวจบอกอะไรบ้าง ? 2:22 เหตุผลที่ควรตรวจ Epigenetic #อายุยืน ที่วางแผนได้ . แนะนำโปรแกรมดูแลสุขภาพเฉพาะบุคคล ค้นหาปัจจัยความเสื่อมชราระดับเซลล์ [Hallmarks of Aging] รู้ภาวะสุขภาพก่อนเสี่ยง พร้อมประเมินอายุร่างกาย สุขภาพสมอง วางแผนดูแลสุขภาพในระยะยาว คลิกที่นี่ https://smtvj.com/Longevity-programs . #AgeFriendlyHospital #โรงพยาบาลสมิติเวชศรีนครินทร์ #เราไม่อยากให้ใครป่วย 📞ติดต่อนัดหมายแพทย์ ได้ที่ 02-022-2086 หรือ info@samitivej.co.th Samitivej Virtual Hospital : LINE @Samitivej Website : https://www.samitivejhospitals.com Facebook : Samitivej Club https://www.youtube-nocookie.com/embed/g9NSzrjrc6w 168 2025-07-29T05:58:27.000Z 2026-10-22T19:54:19.351Z https://longevityharbor.com/de/watch/g9NSzrjrc6w ภาวะเหนือพันธุกรรม Epigenetic คืออะไร วางแผนอายุยืน เริ่มต้นที่การตรวจประเมินความแก่ชรา https://i.ytimg.com/vi/g9NSzrjrc6w/hqdefault.jpg ภาวะเหนือพันธุกรรม (Epigenetic) คือ การเปลี่ยนแปลงของสิ่งมีชีวิตที่ได้รับมาจากพ่อ-แม่ โดยที่ไม่ได้มีการเปลี่ยนแปลงจากลำดับเบส ช่วยให้เราได้ทราบถึงการเกิดความชรา ซึ่งในปัจจุบันเราสามารถตรวจดู Epigenetic ได้ และนำไปสู่การปรับวิธีการใช้ชีวิต เพื่อให้เรามีสุขภาพที่ดีและมีคุณภาพชีวิตที่ยืนยาว ขอขอบคุณข้อมูลจาก นพ.วิทูร จุลรัตนาภรณ์ อายุแพทย์โรคหัวใจและแพทย์ผู้ดูแลด้านเวชศาสตร์ชะลอวัย . 0:23 ภาวะเหนือพันธุกรรม #Epigenetic คืออะไร ? 1:06 #ภาวะเหนือพันธุกรรม มีหลายกลไก อะไรบ้าง ? 1:59 Epigenetic มีประโยชน์อย่างไร ตรวจได้อย่างไร และ ผลการตรวจบอกอะไรบ้าง ? 2:22 เหตุผลที่ควรตรวจ Epigenetic #อายุยืน ที่วางแผนได้ . แนะนำโปรแกรมดูแลสุขภาพเฉพาะบุคคล ค้นหาปัจจัยความเสื่อมชราระดับเซลล์ [Hallmarks of Aging] รู้ภาวะสุขภาพก่อนเสี่ยง พร้อมประเมินอายุร่างกาย สุขภาพสมอง วางแผนดูแลสุขภาพในระยะยาว คลิกที่นี่ https://smtvj.com/Longevity-programs . #AgeFriendlyHospital #โรงพยาบาลสมิติเวชศรีนครินทร์ #เราไม่อยากให้ใครป่วย 📞ติดต่อนัดหมายแพทย์ ได้ที่ 02-022-2086 หรือ info@samitivej.co.th Samitivej Virtual Hospital : LINE @Samitivej Website : https://www.samitivejhospitals.com Facebook : Samitivej Club https://www.youtube-nocookie.com/embed/g9NSzrjrc6w 168 2025-07-29T05:58:27.000Z 2026-10-22T19:54:19.351Z https://longevityharbor.com/en/watch/g9zUtTjm26Q Epigenetic clocks: generations, life transitions and limits of biological age https://i.ytimg.com/vi/g9zUtTjm26Q/hqdefault.jpg The description presents epigenetic clocks as DNA-methylation tests for biological age, distinguishes three clock generations, links life transitions and lifestyle to faster or slower aging, and says clinical use for individuals is not yet supported. https://www.youtube-nocookie.com/embed/g9zUtTjm26Q 2113 2026-02-27T04:12:00.000Z 2026-10-23T02:19:39.554Z https://longevityharbor.com/de/watch/g9zUtTjm26Q Epigenetische Uhren: Generationen, Lebensübergänge und Grenzen des biologischen Alters https://i.ytimg.com/vi/g9zUtTjm26Q/hqdefault.jpg Die Beschreibung stellt epigenetische Uhren als DNA-Methylierungs-Tests für biologisches Alter vor, unterscheidet drei Uhren-Generationen, verbindet Lebensübergänge und Lebensstil mit schnellerem oder langsamerem Altern und sagt, dass die klinische Nutzung für Einzelpersonen noch nicht belegt ist. https://www.youtube-nocookie.com/embed/g9zUtTjm26Q 2113 2026-02-27T04:12:00.000Z 2026-10-23T02:19:39.554Z https://longevityharbor.com/en/watch/gDgxlZZUOB8 Dr Chan video description: strength exercise for healthy aging and muscle loss https://i.ytimg.com/vi/gDgxlZZUOB8/hqdefault.jpg The video description says Dr Chan explains why strength exercise matters as we age and why muscle health is often overlooked, covering links to chronic conditions, how common sarcopenia may be in Singapore, and guideline amounts for seniors. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/gDgxlZZUOB8 1501 2026-10-22T02:00:21.000Z 2026-10-22T19:47:15.035Z https://longevityharbor.com/de/watch/gDgxlZZUOB8 Dr-Chan-Videobeschreibung: Krafttraining für gesundes Altern und Muskelverlust https://i.ytimg.com/vi/gDgxlZZUOB8/hqdefault.jpg Die Videobeschreibung sagt, Dr Chan erkläre, warum Krafttraining im Alter wichtig ist und warum Muskelgesundheit oft übersehen wird; behandelt werden Bezüge zu chronischen Erkrankungen, wie häufig Sarkopenie in Singapur sein könnte und empfohlene Mengen für ältere Menschen. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/gDgxlZZUOB8 1501 2026-10-22T02:00:21.000Z 2026-10-22T19:47:15.035Z https://longevityharbor.com/en/watch/gHAUCdgaOs4 The Science Of Slowing Down Aging Is Here And It's Simpler Than You Think https://i.ytimg.com/vi/gHAUCdgaOs4/hqdefault.jpg Why do some people seem twenty years younger than their actual age while others decline rapidly despite similar lifestyles? Dr. Matt Kaeberlein is one of the leading researchers in the biology of aging whose work has shaped geroscience and given executives clarity on what actually drives cellular decline versus supplement industry noise. Dogs age biologically seven times faster than humans, proving aging rates are modifiable through specific biological pathways. In this episode of the Legacy and Longevity Podcast with host Zach Dancel, Dr. Matt Kaeberlein reveals why the mTOR pathway controls whether cells prioritize growth or stress resistance affecting all hallmarks of aging simultaneously, how rapamycin slows aging in every animal tested despite physician hesitation around high-dose transplant medicine versus once-weekly protocols. On why comprehensive blood work plus DEXA scans matter more than biological age clocks, explains diet quality trumps intermittent fasting timing for metabolic optimization, and shares how AI health agents arriving within two years will scale personalized interventions currently limited to wealthy populations. Fifteen additional years of health span are available using today's science for leaders willing to act proactively instead of reactively. Discover how to align your biology with circadian rhythms and build a health span that matches your lifespan. Stop managing symptoms—start mastering your health with daily habits that transform your biology. Discover your path to peak health; to know more, click on the link below: https://navacenter.com/ Follow Legacy and Longevity Podcast: Website: https://legacyandlongevity.com/ Facebook: https://www.facebook.com/people/Legacy-and-Longevity-Podcast/ YouTube: https://www.youtube.com/@LegacyandLongevityPodcast Instagram: https://www.instagram.com/legacyandlongevity/ Follow Zach Dancel: LinkedIn: https://www.linkedin.com/in/zachdancel/ Instagram: https://www.instagram.com/zachdancel Facebook: https://www.facebook.com/zach.dan https://www.youtube-nocookie.com/embed/gHAUCdgaOs4 3986 2025-12-23T14:48:40.000Z 2026-10-22T19:04:38.829Z https://longevityharbor.com/de/watch/gHAUCdgaOs4 The Science Of Slowing Down Aging Is Here And It's Simpler Than You Think https://i.ytimg.com/vi/gHAUCdgaOs4/hqdefault.jpg Why do some people seem twenty years younger than their actual age while others decline rapidly despite similar lifestyles? Dr. Matt Kaeberlein is one of the leading researchers in the biology of aging whose work has shaped geroscience and given executives clarity on what actually drives cellular decline versus supplement industry noise. Dogs age biologically seven times faster than humans, proving aging rates are modifiable through specific biological pathways. In this episode of the Legacy and Longevity Podcast with host Zach Dancel, Dr. Matt Kaeberlein reveals why the mTOR pathway controls whether cells prioritize growth or stress resistance affecting all hallmarks of aging simultaneously, how rapamycin slows aging in every animal tested despite physician hesitation around high-dose transplant medicine versus once-weekly protocols. On why comprehensive blood work plus DEXA scans matter more than biological age clocks, explains diet quality trumps intermittent fasting timing for metabolic optimization, and shares how AI health agents arriving within two years will scale personalized interventions currently limited to wealthy populations. Fifteen additional years of health span are available using today's science for leaders willing to act proactively instead of reactively. Discover how to align your biology with circadian rhythms and build a health span that matches your lifespan. Stop managing symptoms—start mastering your health with daily habits that transform your biology. Discover your path to peak health; to know more, click on the link below: https://navacenter.com/ Follow Legacy and Longevity Podcast: Website: https://legacyandlongevity.com/ Facebook: https://www.facebook.com/people/Legacy-and-Longevity-Podcast/ YouTube: https://www.youtube.com/@LegacyandLongevityPodcast Instagram: https://www.instagram.com/legacyandlongevity/ Follow Zach Dancel: LinkedIn: https://www.linkedin.com/in/zachdancel/ Instagram: https://www.instagram.com/zachdancel Facebook: https://www.facebook.com/zach.dan https://www.youtube-nocookie.com/embed/gHAUCdgaOs4 3986 2025-12-23T14:48:40.000Z 2026-10-22T19:04:38.829Z https://longevityharbor.com/en/watch/gHRIT2k4UhQ Biologisches Alter zurückdrehen - die Schlüssel zur Langlebigkeit? Mit Dr. med. Irmi Huber https://i.ytimg.com/vi/gHRIT2k4UhQ/hqdefault.jpg Gesundheitswesen hat sich Dr. med. Irmi Huber intensiv mit Langlebigkeitsforschung befasst. Als Ärztin, Unternehmerin und Expertin für Longevity verfügt sie über profunde Kenntnisse zu einem langen gesunden Leben. Ihre Leidenschaft für Präventivmedizin hat Irmi zur Spezialistin für einen ganzheitlichen Ansatz gemacht. In ihrer Firma Neotes testet sie das biologische Alter und berät Kunden zu einem individuellen Longevity-Plan. Als überzeugte Befürworterin eines aktiven Lebensstils teilt Irmi ihr umfassendes Wissen zu Ernährung, Bewegung und mentaler Gesundheit für ein langes Leben. In der aktuellen Epigenetik TV-Folge erklärt sie anschaulich, wie man mithilfe von Methylierungstests das biologische Alter bestimmen kann. Sie geht auf die komplexen Zusammenhänge der Epigenetik ein und zeigt auf, wie sich der Lebensstil auf die Genregulation auswirkt. Bei Einflussfaktoren wie Schlaf, Stress und soziale Kontakte betont sie die Wichtigkeit des Gleichgewichts. Am Ende gibt Irmi die Empfehlung, neben Genetik auch Epigenetik zu berücksichtigen, um personalisierte Longevity-Strategien zu entwickeln. Mit ihrer Expertise trägt Irmi dazu bei, ein Bewusstsein für die individuellen biochemischen Vorgänge zu schaffen, die unsere Gesundheit und Langlebigkeit beeinflussen. Prävention und Therapie erfordern einen integrativen Blick, statt sich auf einzelne Marker zu versteifen. Inhalt: 00:00:00 min: Einleitung und Vorstellung 00:03:14 min: Dr. Irmi Hubers Hintergrund, Studium und berufliche Laufbahn 00:12:30 min: Erfahrungen in Florida mit dem Thema Langlebigkeit 00:14:36 min: Therapien für Langlebigkeit in den USA 00:19:31 min: Erklärung von biologischem und chronologischem Alter 00:22:00 min: Beschreibung des Tests von Neotes zum biologischen Alter 00:22:56 min: Erklärung der Epigenetik und Beeinflussbarkeit des biologischen Alters 00:26:00 min: Präventionsmedizin vs. Epigenetik 00:28:08 min: Spirituelle Gesundheit und Epigenetik 00:28:43 min: Aussagekraft von Blutzellen für Organalterung 00:31:00 min: Biomathematisc https://www.youtube-nocookie.com/embed/gHRIT2k4UhQ 3058 2023-11-22T17:00:38.000Z 2026-10-22T17:11:32.783Z https://longevityharbor.com/de/watch/gHRIT2k4UhQ Biologisches Alter zurückdrehen - die Schlüssel zur Langlebigkeit? Mit Dr. med. Irmi Huber https://i.ytimg.com/vi/gHRIT2k4UhQ/hqdefault.jpg Gesundheitswesen hat sich Dr. med. Irmi Huber intensiv mit Langlebigkeitsforschung befasst. Als Ärztin, Unternehmerin und Expertin für Longevity verfügt sie über profunde Kenntnisse zu einem langen gesunden Leben. Ihre Leidenschaft für Präventivmedizin hat Irmi zur Spezialistin für einen ganzheitlichen Ansatz gemacht. In ihrer Firma Neotes testet sie das biologische Alter und berät Kunden zu einem individuellen Longevity-Plan. Als überzeugte Befürworterin eines aktiven Lebensstils teilt Irmi ihr umfassendes Wissen zu Ernährung, Bewegung und mentaler Gesundheit für ein langes Leben. In der aktuellen Epigenetik TV-Folge erklärt sie anschaulich, wie man mithilfe von Methylierungstests das biologische Alter bestimmen kann. Sie geht auf die komplexen Zusammenhänge der Epigenetik ein und zeigt auf, wie sich der Lebensstil auf die Genregulation auswirkt. Bei Einflussfaktoren wie Schlaf, Stress und soziale Kontakte betont sie die Wichtigkeit des Gleichgewichts. Am Ende gibt Irmi die Empfehlung, neben Genetik auch Epigenetik zu berücksichtigen, um personalisierte Longevity-Strategien zu entwickeln. Mit ihrer Expertise trägt Irmi dazu bei, ein Bewusstsein für die individuellen biochemischen Vorgänge zu schaffen, die unsere Gesundheit und Langlebigkeit beeinflussen. Prävention und Therapie erfordern einen integrativen Blick, statt sich auf einzelne Marker zu versteifen. Inhalt: 00:00:00 min: Einleitung und Vorstellung 00:03:14 min: Dr. Irmi Hubers Hintergrund, Studium und berufliche Laufbahn 00:12:30 min: Erfahrungen in Florida mit dem Thema Langlebigkeit 00:14:36 min: Therapien für Langlebigkeit in den USA 00:19:31 min: Erklärung von biologischem und chronologischem Alter 00:22:00 min: Beschreibung des Tests von Neotes zum biologischen Alter 00:22:56 min: Erklärung der Epigenetik und Beeinflussbarkeit des biologischen Alters 00:26:00 min: Präventionsmedizin vs. Epigenetik 00:28:08 min: Spirituelle Gesundheit und Epigenetik 00:28:43 min: Aussagekraft von Blutzellen für Organalterung 00:31:00 min: Biomathematisc https://www.youtube-nocookie.com/embed/gHRIT2k4UhQ 3058 2023-11-22T17:00:38.000Z 2026-10-22T17:11:32.783Z https://longevityharbor.com/en/watch/gMcv1PoeFAk Video description: scarlet beebalm and telomeres, endometriosis, vibration plates https://i.ytimg.com/vi/gMcv1PoeFAk/hqdefault.jpg The description says Dr. Mike and Dr. Crystal discuss scarlet beebalm and telomere length, endometriosis nutrition and vibration plates; it reports no results, and the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/gMcv1PoeFAk 1239 2026-04-09T21:40:50.000Z 2026-10-23T01:35:38.173Z https://longevityharbor.com/de/watch/gMcv1PoeFAk Videobeschreibung: Scharlach-Bienenmelisse und Telomere, Endometriose, Vibrationsplatten https://i.ytimg.com/vi/gMcv1PoeFAk/hqdefault.jpg Laut Beschreibung besprechen Dr. Mike und Dr. Crystal Scharlach-Bienenmelisse und Telomerlänge, Endometriose-Ernährung und Vibrationsplatten; Ergebnisse nennt sie nicht, und Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/gMcv1PoeFAk 1239 2026-04-09T21:40:50.000Z 2026-10-23T01:35:38.173Z https://longevityharbor.com/en/watch/gNmTXA_l8KM Video description: circadian rhythm, sleep timing and health claims https://i.ytimg.com/vi/gNmTXA_l8KM/hqdefault.jpg The description says the video explains the body's internal 24-hour clock, the suprachiasmatic nucleus, light and melatonin, teenage late sleep, and claimed health effects of disrupted rhythms. https://www.youtube-nocookie.com/embed/gNmTXA_l8KM 298 2026-06-19T13:32:05.000Z 2026-10-22T23:56:50.114Z https://longevityharbor.com/de/watch/gNmTXA_l8KM Videobeschreibung: circadianer Rhythmus, Schlafzeitpunkt und Gesundheitsaussagen https://i.ytimg.com/vi/gNmTXA_l8KM/hqdefault.jpg Laut Beschreibung erklärt das Video die innere 24-Stunden-Uhr, den Nucleus suprachiasmaticus, Licht und Melatonin, spätes Schlafen bei Teenagern und behauptete Gesundheitseffekte gestörter Rhythmen. https://www.youtube-nocookie.com/embed/gNmTXA_l8KM 298 2026-06-19T13:32:05.000Z 2026-10-22T23:56:50.114Z https://longevityharbor.com/en/watch/gOHEBJs7DIc Conference report: cellular senescence and infection at ICSA Rome 2025 https://i.ytimg.com/vi/gOHEBJs7DIc/hqdefault.jpg A meeting report on the 10th ICSA conference in Rome (17–19 September 2025) says infection-driven senescence was a recurring theme across virology, immunology and aging sessions. https://www.youtube-nocookie.com/embed/gOHEBJs7DIc 116 2026-01-06T17:05:50.000Z 2026-10-23T02:57:11.726Z https://longevityharbor.com/de/watch/gOHEBJs7DIc Tagungsbericht: Zelluläre Seneszenz und Infektion bei ICSA Rom 2025 https://i.ytimg.com/vi/gOHEBJs7DIc/hqdefault.jpg Ein Tagungsbericht zur 10. ICSA-Konferenz in Rom (17.–19. September 2025) nennt infektionsgetriebene Seneszenz als wiederkehrendes Thema in virologischen, immunologischen und Alterns-Sitzungen. https://www.youtube-nocookie.com/embed/gOHEBJs7DIc 116 2026-01-06T17:05:50.000Z 2026-10-23T02:57:11.726Z https://longevityharbor.com/en/watch/gSIdKuS6DFo Video description: five morning nutrition strategies for muscle strength after 60 https://i.ytimg.com/vi/gSIdKuS6DFo/hqdefault.jpg The description says the video covers five morning nutrition strategies that may support muscle strength, mobility and circulation after 60, and stresses combining nutrition with resistance exercise. https://www.youtube-nocookie.com/embed/gSIdKuS6DFo 1130 2026-10-06T23:54:08.000Z 2026-10-22T21:15:34.861Z https://longevityharbor.com/de/watch/gSIdKuS6DFo Videobeschreibung: fünf Ernährungsstrategien am Morgen für Muskelkraft ab 60 https://i.ytimg.com/vi/gSIdKuS6DFo/hqdefault.jpg Laut Beschreibung behandelt das Video fünf Ernährungsstrategien am Morgen, die Muskelkraft, Mobilität und Durchblutung ab 60 unterstützen könnten, und betont die Kombination von Ernährung mit Krafttraining. https://www.youtube-nocookie.com/embed/gSIdKuS6DFo 1130 2026-10-06T23:54:08.000Z 2026-10-22T21:15:34.861Z https://longevityharbor.com/en/watch/gWpQS-fp-Fg The ONLY 10 Exercises You Need to do After 50, 60, 70 Years https://i.ytimg.com/vi/gWpQS-fp-Fg/hqdefault.jpg 👇 FREE Exercise Guide - Build Incredible Strength 💪 https://mind-body-horizons.kit.com/313492e6f9 If you want to get stronger, move better, and feel like you’re 20 years younger, then this video is perfect for you! Physiotherapist, Shrey Vazir, will show you 10 Anti-Aging Exercises you need in your 50s, 60s and 70s, while also sharing 2 exercise mistakes you need to avoid! 👇 Watch me next!: 🔹Do THIS Every Day for Stronger Legs (Ages 60+) https://youtu.be/2nyG-gc-VeQ 🔹 ONE Exercise that Instantly Improves Walking (Ages 60+): https://youtu.be/3ShaUs-wDb0?si=iz2gZFtvMcFF44fR 🔹 The ONLY 3 Exercises you NEED to Improve Leg Circulation: https://youtu.be/OTwdMxlm-ik ⏰ TIMESTAMPS ⏰ 0:00 - How to move and feel like you're 20 Years Younger! 0:27 - #1 Leg Strength Exercise for Older Adults 1:36 - 10-Step Guide for Incredible Strength 3:03 - Biggest Exercise Mistake 3:26 - Groundbreaking Study Reveals Anti-Aging Exercise Approach 4:02 - How to Improve your Strength, Stability and Endurance 5:53 - A Fantastic Exercise to Improve Posture 6:47 - How to Live Longer by Strengthening Your Grip! 10:18 - The Push-Pull-Legs Framework 11:32 - Simple 10-Minute Routine to Improve Leg Strength ====================================================== ⚠️ DISCLAIMER ⚠️ The content on this website and related Company properties, including exercises, videos, documents, and other materials, is provided for educational and informational purposes only and does not constitute medical advice, diagnosis, or treatment. Accessing or using this content does not create a therapist–client, doctor–patient, or healthcare provider–patient relationship. The information is based on current medical research and/or the experience of the presenter; however, medical knowledge is constantly evolving, and the content may not be fully up to date, comprehensive, or applicable to your specific condition. Always seek the advice of a qualified physician or healthcare professional with any questions regarding a medical condition and before beginning https://www.youtube-nocookie.com/embed/gWpQS-fp-Fg 711 2025-01-31T13:54:31.000Z 2026-10-22T19:02:25.581Z https://longevityharbor.com/de/watch/gWpQS-fp-Fg The ONLY 10 Exercises You Need to do After 50, 60, 70 Years https://i.ytimg.com/vi/gWpQS-fp-Fg/hqdefault.jpg 👇 FREE Exercise Guide - Build Incredible Strength 💪 https://mind-body-horizons.kit.com/313492e6f9 If you want to get stronger, move better, and feel like you’re 20 years younger, then this video is perfect for you! Physiotherapist, Shrey Vazir, will show you 10 Anti-Aging Exercises you need in your 50s, 60s and 70s, while also sharing 2 exercise mistakes you need to avoid! 👇 Watch me next!: 🔹Do THIS Every Day for Stronger Legs (Ages 60+) https://youtu.be/2nyG-gc-VeQ 🔹 ONE Exercise that Instantly Improves Walking (Ages 60+): https://youtu.be/3ShaUs-wDb0?si=iz2gZFtvMcFF44fR 🔹 The ONLY 3 Exercises you NEED to Improve Leg Circulation: https://youtu.be/OTwdMxlm-ik ⏰ TIMESTAMPS ⏰ 0:00 - How to move and feel like you're 20 Years Younger! 0:27 - #1 Leg Strength Exercise for Older Adults 1:36 - 10-Step Guide for Incredible Strength 3:03 - Biggest Exercise Mistake 3:26 - Groundbreaking Study Reveals Anti-Aging Exercise Approach 4:02 - How to Improve your Strength, Stability and Endurance 5:53 - A Fantastic Exercise to Improve Posture 6:47 - How to Live Longer by Strengthening Your Grip! 10:18 - The Push-Pull-Legs Framework 11:32 - Simple 10-Minute Routine to Improve Leg Strength ====================================================== ⚠️ DISCLAIMER ⚠️ The content on this website and related Company properties, including exercises, videos, documents, and other materials, is provided for educational and informational purposes only and does not constitute medical advice, diagnosis, or treatment. Accessing or using this content does not create a therapist–client, doctor–patient, or healthcare provider–patient relationship. The information is based on current medical research and/or the experience of the presenter; however, medical knowledge is constantly evolving, and the content may not be fully up to date, comprehensive, or applicable to your specific condition. Always seek the advice of a qualified physician or healthcare professional with any questions regarding a medical condition and before beginning https://www.youtube-nocookie.com/embed/gWpQS-fp-Fg 711 2025-01-31T13:54:31.000Z 2026-10-22T19:02:25.581Z https://longevityharbor.com/en/watch/gc-i1yKigEs Longevity supplements: what human trials actually show https://i.ytimg.com/vi/gc-i1yKigEs/hqdefault.jpg The description says NMN and NR can double circulating NAD+ within two weeks, but no human trial has shown they extend lifespan; the longest study lasted twelve weeks. https://www.youtube-nocookie.com/embed/gc-i1yKigEs 90 2026-09-08T12:45:23.000Z 2026-10-22T22:24:06.076Z https://longevityharbor.com/de/watch/gc-i1yKigEs Longevity-Supplemente: Was menschliche Studien wirklich zeigen https://i.ytimg.com/vi/gc-i1yKigEs/hqdefault.jpg Laut Beschreibung können NMN und NR zirkulierendes NAD+ binnen zwei Wochen verdoppeln, doch keine menschliche Studie zeigte eine Lebensverlängerung; die längste dauerte zwölf Wochen. https://www.youtube-nocookie.com/embed/gc-i1yKigEs 90 2026-09-08T12:45:23.000Z 2026-10-22T22:24:06.076Z https://longevityharbor.com/en/watch/gdkZK8jwl5E Brain tumor survivor discusses aging hallmarks and biological aging in a podcast description https://i.ytimg.com/vi/gdkZK8jwl5E/hqdefault.jpg The description says Chris Mirabile survived a large brain tumor at 16 and now discusses longevity, the 12 hallmarks of aging, biological aging, mitochondria, inflammation and lifestyle habits. It names topics but reports no study results or measured outcomes. https://www.youtube-nocookie.com/embed/gdkZK8jwl5E 3516 2026-05-08T00:00:06.000Z 2026-10-23T01:07:14.942Z https://longevityharbor.com/de/watch/gdkZK8jwl5E Hirntumor-Überlebender spricht in einer Podcast-Beschreibung über Hallmarks des Alterns und biologis https://i.ytimg.com/vi/gdkZK8jwl5E/hqdefault.jpg Laut Beschreibung überlebte Chris Mirabile mit 16 einen großen Hirntumor und spricht nun über Langlebigkeit, die 12 Hallmarks des Alterns, biologisches Altern, Mitochondrien, Entzündung und Lebensgewohnheiten. Die Themen werden benannt, aber keine Studienergebnisse oder gemessenen Endpunkte berichtet. https://www.youtube-nocookie.com/embed/gdkZK8jwl5E 3516 2026-05-08T00:00:06.000Z 2026-10-23T01:07:14.942Z https://longevityharbor.com/en/watch/gi4PRURX-HI Circadian rhythms explained: body clocks and tissue ageing research https://i.ytimg.com/vi/gi4PRURX-HI/hqdefault.jpg The description says circadian rhythms are roughly 24-hour biological cycles that align sleep, appetite, digestion, hormone release and body temperature with day and night; a Barcelona lab studies how these clocks are coordinated and how their disruption relates to tissue ageing. https://www.youtube-nocookie.com/embed/gi4PRURX-HI 128 2026-08-27T09:00:34.000Z 2026-10-22T22:41:41.776Z https://longevityharbor.com/de/watch/gi4PRURX-HI Circadiane Rhythmen erklärt: Körperuhren und Gewebealterung im Fokus https://i.ytimg.com/vi/gi4PRURX-HI/hqdefault.jpg Laut Beschreibung sind circadiane Rhythmen biologische Zyklen von etwa 24 Stunden, die Schlaf, Appetit, Verdauung, Hormonausschüttung und Körpertemperatur mit Tag und Nacht abstimmen; ein Labor in Barcelona untersucht, wie diese Uhren koordiniert werden und wie ihre Störung mit Gewebealterung zusammenhängt. https://www.youtube-nocookie.com/embed/gi4PRURX-HI 128 2026-08-27T09:00:34.000Z 2026-10-22T22:41:41.776Z https://longevityharbor.com/en/watch/giYeSWleNSU Video description links mitochondrial energy, blood flow and aging https://i.ytimg.com/vi/giYeSWleNSU/hqdefault.jpg The description says mitochondrial dysfunction is one of 12 hallmarks of aging and contrasts about 36 ATP per glucose with oxygen against about 2 without enough oxygen. It credits dry needling with raising blood flow and oxygen and links more energy to less age-related decline. https://www.youtube-nocookie.com/embed/giYeSWleNSU 567 2026-08-27T17:20:13.000Z 2026-10-22T22:40:15.774Z https://longevityharbor.com/de/watch/giYeSWleNSU Videobeschreibung verknüpft Mitochondrienenergie, Blutfluss und Altern https://i.ytimg.com/vi/giYeSWleNSU/hqdefault.jpg Die Beschreibung nennt mitochondriale Dysfunktion als eines von 12 Hallmarks des Alterns und stellt etwa 36 ATP pro Glukose mit Sauerstoff etwa 2 ohne ausreichend Sauerstoff gegenüber. Sie schreibt Dry Needling mehr Blutfluss und Sauerstoff zu und verknüpft mehr Energie mit weniger altersbezogenem Abbau. https://www.youtube-nocookie.com/embed/giYeSWleNSU 567 2026-08-27T17:20:13.000Z 2026-10-22T22:40:15.774Z https://longevityharbor.com/en/watch/gmjkikAcLk4 Kann man mit NMN / NAD+ biologisch wieder 20 werden? (Studien!) // David Sinclair https://i.ytimg.com/vi/gmjkikAcLk4/hqdefault.jpg Im heutigen Video geht’s um NAD+, NMN und NR: Warum Dr. David Sinclair jeden Tag NMN nimmt, wie es durch Erhöhen der NAD+ Level Altern aufhält, wo man das aktuell beste NMN Präparat* bekommt und wie man NMN korrekt einnimmt und lagert, seht ihr in diesem Video! Wir sprechen außerdem über die aktuell besten NAD+ Booster weltweit - wie Basis / Elysium* von Leonard Guarente, und die Zukunft der NAD+ Booster: Das Präparat MIB-626 von Metrobiotech*, das gerade noch an Menschen getestet wird - also alllles, was ihr über NMN und NAD+ wissen müsst. #DavidSinclair #NMN #NAD+ Werbung: Die nachfolgenden Produkt-Links sind Affiliate Links (*): Wenn du über diese Links etwas kaufst, erhalte ich eine kleine Vergütung, für dich entstehen dabei keinerlei Mehrkosten. Du kannst natürlich die Sachen auch woanders kaufen, ganz wie du magst. Danke, dass du meinen Kanal unterstützt. :) Disclaimer: Bitte sprecht unbedingt mit eurem Arzt, bevor ihr in Erwägung zieht, Supplements auszuprobieren - ich bin kein Arzt und gebe keine medizinischen Ratschläge. 💊Supplements, die ich nehme, um Altern aufzuhalten - auf alles 15% Rabatt mit dem Code "ANASTASIA":💊 * NMN: in EU hergestelltes Longevir NMN: https://avea-life.com/de/products/nmn?aff=ANASTASIARASTOR (1 Kapsel morgens mit Wasser) * Mein Longevity Bundle / alle Longevity-Wirkstoffe in einem Bundle: NMN, TMG, Trans-Resveratrol, Coenzym Q10, Pterostilben, Apigenin, Kollagen: https://avea-life.com/de/products/longevity-bundle?country=DE&utm_source=YOUTUBE&utm_medium=INFLUENCER&utm_campaign=YT-DACH-INFL-PURC-COLL-ANASTASIA-14462544&utm_term=BROD-YTD_-DACH-LONG-COLL&utm_content=COLL-VID-UGCC-HOME-BENE-D15X (jeden Morgen 1 Kapsel NMN, 1 Kapsel Booster, 1 Sachet Kollagenpulver in Wasser) * Essentials: Vitamin D3 und K2, Omega 3 aus Algenöl, Magnesiumbiglycinat, Zink, B-Vitamine: https://avea-life.com/de/products/essentials (4 Kapseln täglich nach einer Mahlzeit) * Spermidin, Fistetin und Quercetin: https://avea-life.com/de/products/cell-primer?country=DE&utm_source=YOUTUBE&utm_medium= https://www.youtube-nocookie.com/embed/gmjkikAcLk4 712 2020-06-09T12:01:01.000Z 2026-10-22T17:43:42.525Z https://longevityharbor.com/de/watch/gmjkikAcLk4 Kann man mit NMN / NAD+ biologisch wieder 20 werden? (Studien!) // David Sinclair https://i.ytimg.com/vi/gmjkikAcLk4/hqdefault.jpg Im heutigen Video geht’s um NAD+, NMN und NR: Warum Dr. David Sinclair jeden Tag NMN nimmt, wie es durch Erhöhen der NAD+ Level Altern aufhält, wo man das aktuell beste NMN Präparat* bekommt und wie man NMN korrekt einnimmt und lagert, seht ihr in diesem Video! Wir sprechen außerdem über die aktuell besten NAD+ Booster weltweit - wie Basis / Elysium* von Leonard Guarente, und die Zukunft der NAD+ Booster: Das Präparat MIB-626 von Metrobiotech*, das gerade noch an Menschen getestet wird - also alllles, was ihr über NMN und NAD+ wissen müsst. #DavidSinclair #NMN #NAD+ Werbung: Die nachfolgenden Produkt-Links sind Affiliate Links (*): Wenn du über diese Links etwas kaufst, erhalte ich eine kleine Vergütung, für dich entstehen dabei keinerlei Mehrkosten. Du kannst natürlich die Sachen auch woanders kaufen, ganz wie du magst. Danke, dass du meinen Kanal unterstützt. :) Disclaimer: Bitte sprecht unbedingt mit eurem Arzt, bevor ihr in Erwägung zieht, Supplements auszuprobieren - ich bin kein Arzt und gebe keine medizinischen Ratschläge. 💊Supplements, die ich nehme, um Altern aufzuhalten - auf alles 15% Rabatt mit dem Code "ANASTASIA":💊 * NMN: in EU hergestelltes Longevir NMN: https://avea-life.com/de/products/nmn?aff=ANASTASIARASTOR (1 Kapsel morgens mit Wasser) * Mein Longevity Bundle / alle Longevity-Wirkstoffe in einem Bundle: NMN, TMG, Trans-Resveratrol, Coenzym Q10, Pterostilben, Apigenin, Kollagen: https://avea-life.com/de/products/longevity-bundle?country=DE&utm_source=YOUTUBE&utm_medium=INFLUENCER&utm_campaign=YT-DACH-INFL-PURC-COLL-ANASTASIA-14462544&utm_term=BROD-YTD_-DACH-LONG-COLL&utm_content=COLL-VID-UGCC-HOME-BENE-D15X (jeden Morgen 1 Kapsel NMN, 1 Kapsel Booster, 1 Sachet Kollagenpulver in Wasser) * Essentials: Vitamin D3 und K2, Omega 3 aus Algenöl, Magnesiumbiglycinat, Zink, B-Vitamine: https://avea-life.com/de/products/essentials (4 Kapseln täglich nach einer Mahlzeit) * Spermidin, Fistetin und Quercetin: https://avea-life.com/de/products/cell-primer?country=DE&utm_source=YOUTUBE&utm_medium= https://www.youtube-nocookie.com/embed/gmjkikAcLk4 712 2020-06-09T12:01:01.000Z 2026-10-22T17:43:42.525Z https://longevityharbor.com/en/watch/gni04m99nRA Kaeberlein on why rapamycin trials in Alzheimer's are scarce https://i.ytimg.com/vi/gni04m99nRA/hqdefault.jpg In this video description, Dr. Matt Kaeberlein says Alzheimer's research has not prioritized biological aging, which he calls the disease's primary risk factor, and links the lack of rapamycin trials to funding and reputational barriers. https://www.youtube-nocookie.com/embed/gni04m99nRA 529 2026-09-25T07:01:42.000Z 2026-10-22T21:50:37.620Z https://longevityharbor.com/de/watch/gni04m99nRA Kaeberlein dazu, warum Rapamycin-Studien bei Alzheimer selten sind https://i.ytimg.com/vi/gni04m99nRA/hqdefault.jpg In dieser Videobeschreibung sagt Dr. Matt Kaeberlein, die Alzheimer-Forschung habe das biologische Altern nicht priorisiert, das er als wichtigsten Risikofaktor der Krankheit bezeichnet; den Mangel an Rapamycin-Studien führt er auf Finanzierungs- und Reputationshürden zurück. https://www.youtube-nocookie.com/embed/gni04m99nRA 529 2026-09-25T07:01:42.000Z 2026-10-22T21:50:37.620Z https://longevityharbor.com/en/watch/goqOvjutvc8 Supporting Healthy Aging: Nutrition for Seniors https://i.ytimg.com/vi/goqOvjutvc8/hqdefault.jpg Featuring Registered Dietitians Kate Park and Michele Werstuck https://www.youtube-nocookie.com/embed/goqOvjutvc8 2443 2020-10-09T20:16:59.000Z 2026-10-23T01:53:57.161Z https://longevityharbor.com/de/watch/goqOvjutvc8 Supporting Healthy Aging: Nutrition for Seniors https://i.ytimg.com/vi/goqOvjutvc8/hqdefault.jpg Featuring Registered Dietitians Kate Park and Michele Werstuck https://www.youtube-nocookie.com/embed/goqOvjutvc8 2443 2020-10-09T20:16:59.000Z 2026-10-23T01:53:57.161Z https://longevityharbor.com/en/watch/gpRvrS9-TdA South San Francisco’s NewLimit aims to tackle diseases of aging through epigenetic reprogramming. https://i.ytimg.com/vi/gpRvrS9-TdA/hqdefault.jpg South San Francisco’s NewLimit aims to tackle diseases of aging through epigenetic reprogramming. https://www.youtube-nocookie.com/embed/gpRvrS9-TdA 179 2026-02-20T13:56:41.000Z 2026-10-22T18:54:03.220Z https://longevityharbor.com/de/watch/gpRvrS9-TdA South San Francisco’s NewLimit aims to tackle diseases of aging through epigenetic reprogramming. https://i.ytimg.com/vi/gpRvrS9-TdA/hqdefault.jpg South San Francisco’s NewLimit aims to tackle diseases of aging through epigenetic reprogramming. https://www.youtube-nocookie.com/embed/gpRvrS9-TdA 179 2026-02-20T13:56:41.000Z 2026-10-22T18:54:03.220Z https://longevityharbor.com/en/watch/guVGZ94YgzQ Natalia Mitin at ARDD2024: Cellular senescence solutions: pioneering advances in clinical practice https://i.ytimg.com/vi/guVGZ94YgzQ/hqdefault.jpg Natalia Mitin, Sapere Bio, USA, presents at the 11th Aging Research and Drug Discovery meeting: Cellular senescence solutions: pioneering advances in clinical practice https://www.youtube-nocookie.com/embed/guVGZ94YgzQ 1261 2025-03-26T09:51:47.000Z 2026-10-22T19:21:23.293Z https://longevityharbor.com/de/watch/guVGZ94YgzQ Natalia Mitin at ARDD2024: Cellular senescence solutions: pioneering advances in clinical practice https://i.ytimg.com/vi/guVGZ94YgzQ/hqdefault.jpg Natalia Mitin, Sapere Bio, USA, presents at the 11th Aging Research and Drug Discovery meeting: Cellular senescence solutions: pioneering advances in clinical practice https://www.youtube-nocookie.com/embed/guVGZ94YgzQ 1261 2025-03-26T09:51:47.000Z 2026-10-22T19:21:23.293Z https://longevityharbor.com/en/watch/gw7gHrga1IA 🚫 Why I Stopped Taking NMN | The Truth About NMN and NAD+ for Longevity | Dr. Joanette https://i.ytimg.com/vi/gw7gHrga1IA/hqdefault.jpg I used to take NMN (nicotinamide mononucleotide) daily—but then I stopped. Not because of what it did, but because of what it didn’t do. I’m Dr. Joanette, your longevity expert, and in this video I’ll share the truth behind NMN and NAD+, what the science really says, and the four lifestyle strategies I now use instead to naturally boost my energy, focus, and longevity. We’ll explore the latest research on NMN supplements, how they impact NAD+ levels and ATP production, and why lifestyle habits like sleep, exercise, and stress reduction may be far more powerful for healthy aging. ⏱ Timestamps: 0:00 Why I stopped taking NMN 0:49 What NMN and NAD+ actually are 2:11 My 6-month NMN experiment 2:31 What the research really shows 3:32 The truth about quick-fix supplements 4:38 The 4 things I do instead 5:52 Sleep & connection 7:56 Final takeaway 🌐 Resources & Links: 🍽 Learn more about my Longevity Plate: https://growwithdrjoanette.com/ 🧬 Research on NAD+ & NMN studies: https://pubmed.ncbi.nlm.nih.gov/39116016/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8550608/ Don’t forget to subscribe for more health tips and recipes! @DrJoanette Website: growwithdrjoanette.com Follow for More! Instagram: https://www.instagram.com/growwithdrjoanette Facebook: https://www.facebook.com/Dr.JoanetteMD Twitter: https://www.x.com/@growwithdrjo TikTok: https://www.tiktok.com/@drjoanette DISCLAIMER: As a physician passionate about health education, I want to be clear that while I share evidence-based information, I am not your personal doctor and don’t know your unique medical history. The recipes and wellness tips I provide are for educational purposes only. Before making any dietary or lifestyle changes based on my content, please consult with your healthcare provider, who understands your specific health needs and can offer personalized guidance. Your well-being matters, and I’m here to support your health journey alongside the care you receive from your medical team. https://www.youtube-nocookie.com/embed/gw7gHrga1IA 543 2025-10-15T20:00:37.000Z 2026-10-22T18:43:09.884Z https://longevityharbor.com/de/watch/gw7gHrga1IA 🚫 Why I Stopped Taking NMN | The Truth About NMN and NAD+ for Longevity | Dr. Joanette https://i.ytimg.com/vi/gw7gHrga1IA/hqdefault.jpg I used to take NMN (nicotinamide mononucleotide) daily—but then I stopped. Not because of what it did, but because of what it didn’t do. I’m Dr. Joanette, your longevity expert, and in this video I’ll share the truth behind NMN and NAD+, what the science really says, and the four lifestyle strategies I now use instead to naturally boost my energy, focus, and longevity. We’ll explore the latest research on NMN supplements, how they impact NAD+ levels and ATP production, and why lifestyle habits like sleep, exercise, and stress reduction may be far more powerful for healthy aging. ⏱ Timestamps: 0:00 Why I stopped taking NMN 0:49 What NMN and NAD+ actually are 2:11 My 6-month NMN experiment 2:31 What the research really shows 3:32 The truth about quick-fix supplements 4:38 The 4 things I do instead 5:52 Sleep & connection 7:56 Final takeaway 🌐 Resources & Links: 🍽 Learn more about my Longevity Plate: https://growwithdrjoanette.com/ 🧬 Research on NAD+ & NMN studies: https://pubmed.ncbi.nlm.nih.gov/39116016/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8550608/ Don’t forget to subscribe for more health tips and recipes! @DrJoanette Website: growwithdrjoanette.com Follow for More! Instagram: https://www.instagram.com/growwithdrjoanette Facebook: https://www.facebook.com/Dr.JoanetteMD Twitter: https://www.x.com/@growwithdrjo TikTok: https://www.tiktok.com/@drjoanette DISCLAIMER: As a physician passionate about health education, I want to be clear that while I share evidence-based information, I am not your personal doctor and don’t know your unique medical history. The recipes and wellness tips I provide are for educational purposes only. Before making any dietary or lifestyle changes based on my content, please consult with your healthcare provider, who understands your specific health needs and can offer personalized guidance. Your well-being matters, and I’m here to support your health journey alongside the care you receive from your medical team. https://www.youtube-nocookie.com/embed/gw7gHrga1IA 543 2025-10-15T20:00:37.000Z 2026-10-22T18:43:09.884Z https://longevityharbor.com/en/watch/gzne8O_rvRw Top Nutritionist Reveals Best Fasting Techniques for LONGEVITY https://i.ytimg.com/vi/gzne8O_rvRw/hqdefault.jpg Discover the real secret to eating for longevity in this video. Learn about the benefits of fasting for longevity and how it can improve your overall health and wellness. #nutritionassistance #longevity #intermittentfasting #prolongedfasting #agereversal #aginggracefully #peptides #dietforlongevity #fasting https://www.youtube-nocookie.com/embed/gzne8O_rvRw 92 2025-09-29T16:30:29.000Z 2026-10-22T18:32:09.090Z https://longevityharbor.com/de/watch/gzne8O_rvRw Top Nutritionist Reveals Best Fasting Techniques for LONGEVITY https://i.ytimg.com/vi/gzne8O_rvRw/hqdefault.jpg Discover the real secret to eating for longevity in this video. Learn about the benefits of fasting for longevity and how it can improve your overall health and wellness. #nutritionassistance #longevity #intermittentfasting #prolongedfasting #agereversal #aginggracefully #peptides #dietforlongevity #fasting https://www.youtube-nocookie.com/embed/gzne8O_rvRw 92 2025-09-29T16:30:29.000Z 2026-10-22T18:32:09.090Z https://longevityharbor.com/en/watch/h0DNaqsJpg8 Valter Longo | Fasting Mimicking Diets Longevity and Disease - Lugano https://i.ytimg.com/vi/h0DNaqsJpg8/hqdefault.jpg Valter Longo delivered the closing session at the IBSA Foundation Forum "Senotherapeutics Revolution: Transforming Aging and Cancer Therapy." In his presentation titled "Fasting Mimicking Diets, Longevity, and Disease," Professor Longo, Director of the USC Longevity Institute, explored the growing body of evidence supporting Fasting Mimicking Diets (FMDs) as powerful tools to extend healthspan and reduce the incidence of cancer and age-related diseases. Did you like the video? Don't miss our updates: https://www.ibsafoundation.org/it/ 🔔 Follow us! Instagram: https://www.instagram.com/ibsa_foundation/ Facebook: https://www.facebook.com/IBSAFoundation/ LinkedIn: https://www.linkedin.com/company/ibsa-foundation-for-scientific-research Subscribe to the newsletter: https://www.ibsafoundation.org/it/newsletter https://www.youtube-nocookie.com/embed/h0DNaqsJpg8 4724 2025-07-22T06:00:38.000Z 2026-10-22T18:54:06.916Z https://longevityharbor.com/de/watch/h0DNaqsJpg8 Valter Longo | Fasting Mimicking Diets Longevity and Disease - Lugano https://i.ytimg.com/vi/h0DNaqsJpg8/hqdefault.jpg Valter Longo delivered the closing session at the IBSA Foundation Forum "Senotherapeutics Revolution: Transforming Aging and Cancer Therapy." In his presentation titled "Fasting Mimicking Diets, Longevity, and Disease," Professor Longo, Director of the USC Longevity Institute, explored the growing body of evidence supporting Fasting Mimicking Diets (FMDs) as powerful tools to extend healthspan and reduce the incidence of cancer and age-related diseases. Did you like the video? Don't miss our updates: https://www.ibsafoundation.org/it/ 🔔 Follow us! Instagram: https://www.instagram.com/ibsa_foundation/ Facebook: https://www.facebook.com/IBSAFoundation/ LinkedIn: https://www.linkedin.com/company/ibsa-foundation-for-scientific-research Subscribe to the newsletter: https://www.ibsafoundation.org/it/newsletter https://www.youtube-nocookie.com/embed/h0DNaqsJpg8 4724 2025-07-22T06:00:38.000Z 2026-10-22T18:54:06.916Z https://longevityharbor.com/en/watch/h0wBeRJVunY Circadian Health Explained | Mollie Eastman https://i.ytimg.com/vi/h0wBeRJVunY/hqdefault.jpg Why can you be exhausted all day — but still unable to sleep at night? Sleep expert Mollie Eastman joins Orshi McNaughton to explore chronic insomnia, circadian rhythm disruption, sleep-disordered breathing, and the factors that can keep people trapped in poor sleep despite trying everything. Mollie shares her own experience with sleep anxiety and discusses sleeping medications, REM sleep, sleep apnea and upper airway resistance syndrome, chronobiology, social jet lag, HRV, and wearable sleep tracking. They also explore how light exposure, breathing, cortisol, and daily routines can influence sleep quality and long-term recovery. CHAPTERS 00:00 Women & Chronic Insomnia 01:25 Mollie’s Experience with Sleep Anxiety & Panic Attacks 04:12 Sleeping Pills & Chronic Sleep Problems 08:32 Sleep Quality & REM Sleep 13:54 Sleep Apnea vs. Upper Airway Resistance Syndrome 17:24 Tongue-Tie Release, Nasal Breathing & ENT Interventions 21:07 Chronobiology & Resetting Your Body Clock 26:53 Social Jet Lag, Cortisol & Melatonin 30:58 Balancing Social Life & Sleep 35:14 Sleep Trackers, HRV & Recovery 42:44 Where to Find Mollie Eastman ABOUT MOLLIE EASTMAN Mollie Eastman is a sleep optimization expert and founder of Sleep Is A Skill. Her work focuses on circadian rhythm, chronobiology, sleep tracking, behavioral sleep strategies, and helping people better understand and improve their sleep. Website: https://www.sleepisaskill.com/ Instagram: https://www.instagram.com/sleepisaskill/ THE AGE REVERSAL PROJECT The Age Reversal Project explores the people, science, technologies, and experiments pushing the boundaries of human longevity and healthspan. Hosted by Orshi McNaughton. Website: https://orshimcnaughton.com Substack: https://substack.com/@orshimcnaughton YouTube: https://www.youtube.com/@AgeReversalProject Instagram: https://www.instagram.com/orshimcnaughton/ Subscribe to The Age Reversal Project for conversations with the scientists, physicians, founders, and innovators working at the fronti https://www.youtube-nocookie.com/embed/h0wBeRJVunY 2847 2025-04-08T23:07:01.000Z 2026-10-22T18:54:02.169Z https://longevityharbor.com/de/watch/h0wBeRJVunY Circadian Health Explained | Mollie Eastman https://i.ytimg.com/vi/h0wBeRJVunY/hqdefault.jpg Why can you be exhausted all day — but still unable to sleep at night? Sleep expert Mollie Eastman joins Orshi McNaughton to explore chronic insomnia, circadian rhythm disruption, sleep-disordered breathing, and the factors that can keep people trapped in poor sleep despite trying everything. Mollie shares her own experience with sleep anxiety and discusses sleeping medications, REM sleep, sleep apnea and upper airway resistance syndrome, chronobiology, social jet lag, HRV, and wearable sleep tracking. They also explore how light exposure, breathing, cortisol, and daily routines can influence sleep quality and long-term recovery. CHAPTERS 00:00 Women & Chronic Insomnia 01:25 Mollie’s Experience with Sleep Anxiety & Panic Attacks 04:12 Sleeping Pills & Chronic Sleep Problems 08:32 Sleep Quality & REM Sleep 13:54 Sleep Apnea vs. Upper Airway Resistance Syndrome 17:24 Tongue-Tie Release, Nasal Breathing & ENT Interventions 21:07 Chronobiology & Resetting Your Body Clock 26:53 Social Jet Lag, Cortisol & Melatonin 30:58 Balancing Social Life & Sleep 35:14 Sleep Trackers, HRV & Recovery 42:44 Where to Find Mollie Eastman ABOUT MOLLIE EASTMAN Mollie Eastman is a sleep optimization expert and founder of Sleep Is A Skill. Her work focuses on circadian rhythm, chronobiology, sleep tracking, behavioral sleep strategies, and helping people better understand and improve their sleep. Website: https://www.sleepisaskill.com/ Instagram: https://www.instagram.com/sleepisaskill/ THE AGE REVERSAL PROJECT The Age Reversal Project explores the people, science, technologies, and experiments pushing the boundaries of human longevity and healthspan. Hosted by Orshi McNaughton. Website: https://orshimcnaughton.com Substack: https://substack.com/@orshimcnaughton YouTube: https://www.youtube.com/@AgeReversalProject Instagram: https://www.instagram.com/orshimcnaughton/ Subscribe to The Age Reversal Project for conversations with the scientists, physicians, founders, and innovators working at the fronti https://www.youtube-nocookie.com/embed/h0wBeRJVunY 2847 2025-04-08T23:07:01.000Z 2026-10-22T18:54:02.169Z https://longevityharbor.com/en/watch/h2KAsrWkLOU Six habits for healthy aging after 60: what the cited studies report https://i.ytimg.com/vi/h2KAsrWkLOU/hqdefault.jpg The description lists six everyday habits for healthy aging after 60 and names studies behind them, including daily steps, Mediterranean-style eating, brain training, exercise against falls, social connection and sleep. It is a description only; video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/h2KAsrWkLOU 1420 2026-10-04T12:30:13.000Z 2026-10-22T21:26:42.251Z https://longevityharbor.com/de/watch/h2KAsrWkLOU Sechs Gewohnheiten für gesundes Altern ab 60: was die zitierten Studien berichten https://i.ytimg.com/vi/h2KAsrWkLOU/hqdefault.jpg Die Beschreibung nennt sechs Alltagsgewohnheiten für gesundes Altern ab 60 und die dahinterstehenden Studien, darunter tägliche Schritte, mediterrane Ernährung, Gehirntraining, Bewegung gegen Stürze, soziale Verbundenheit und Schlaf. Es liegt nur die Beschreibung vor; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/h2KAsrWkLOU 1420 2026-10-04T12:30:13.000Z 2026-10-22T21:26:42.251Z https://longevityharbor.com/en/watch/h5KNxbRB45s Lecture description: DNA damage, genomic instability and proposed longevity strategies https://i.ytimg.com/vi/h5KNxbRB45s/hqdefault.jpg The description says this lecture presents genomic instability as the first major hallmark of aging, describes over 70,000 daily DNA attacks from internal processes and external factors such as UV radiation and pollution, and names antioxidant support, cold plunge therapy and lifestyle choices as practical strategies. These are creator claims from the description only. https://www.youtube-nocookie.com/embed/h5KNxbRB45s 858 2025-12-30T12:31:09.000Z 2026-10-23T03:04:15.514Z https://longevityharbor.com/de/watch/h5KNxbRB45s Vortragsbeschreibung: DNA-Schäden, genomische Instabilität und vorgeschlagene Longevity-Strategien https://i.ytimg.com/vi/h5KNxbRB45s/hqdefault.jpg Laut Beschreibung stellt der Vortrag genomische Instabilität als erstes Hauptmerkmal des Alterns vor, nennt über 70.000 tägliche DNA-Angriffe durch interne Prozesse und äußere Faktoren wie UV-Strahlung und Umweltverschmutzung und führt Antioxidantien-Unterstützung, Kaltwasserbäder und Lebensstilentscheidungen als praktische Strategien an. Dies sind Aussagen des Erstellers aus der Beschreibung. https://www.youtube-nocookie.com/embed/h5KNxbRB45s 858 2025-12-30T12:31:09.000Z 2026-10-23T03:04:15.514Z https://longevityharbor.com/en/watch/h61IJ_81jlI Die richtige Ernährung für jede Lebensphase Gesund durch alle Altersstufen https://i.ytimg.com/vi/h61IJ_81jlI/hqdefault.jpg „In diesem Video erfährst du, warum eine abwechslungsreiche und nahrhafte Ernährung so wichtig für deine Gesundheit ist. Egal in welcher Lebensphase du dich befindest, die richtigen Nährstoffe wie Ballaststoffe, Kalzium, Vitamin D und Antioxidantien unterstützen deinen Körper und stärken dein Wohlbefinden. Entdecke einfache Tipps, um deine Ernährung zu optimieren und langfristig gesund zu bleiben! 🍎🥦 #GesundeErnährung #Nährstoffe“ https://www.youtube-nocookie.com/embed/h61IJ_81jlI 93 2024-10-10T19:49:38.000Z 2026-10-22T19:04:43.868Z https://longevityharbor.com/de/watch/h61IJ_81jlI Die richtige Ernährung für jede Lebensphase Gesund durch alle Altersstufen https://i.ytimg.com/vi/h61IJ_81jlI/hqdefault.jpg „In diesem Video erfährst du, warum eine abwechslungsreiche und nahrhafte Ernährung so wichtig für deine Gesundheit ist. Egal in welcher Lebensphase du dich befindest, die richtigen Nährstoffe wie Ballaststoffe, Kalzium, Vitamin D und Antioxidantien unterstützen deinen Körper und stärken dein Wohlbefinden. Entdecke einfache Tipps, um deine Ernährung zu optimieren und langfristig gesund zu bleiben! 🍎🥦 #GesundeErnährung #Nährstoffe“ https://www.youtube-nocookie.com/embed/h61IJ_81jlI 93 2024-10-10T19:49:38.000Z 2026-10-22T19:04:43.868Z https://longevityharbor.com/en/watch/h64iCzUz5Ho Fasting After 40: Are You Losing the Wrong Weight? https://i.ytimg.com/vi/h64iCzUz5Ho/hqdefault.jpg Intermittent fasting after 40: Does it really slow aging, or could you be losing muscle along with body fat? In this science-based investigation, research scientist Marcus examines the evidence behind fasting, longevity, biological aging, and muscle preservation. Can intermittent fasting help you live longer? What does the research actually say about fat-free mass, resistance training, and healthy aging? We examine the CALERIE trial, the DunedinPACE biological aging measurement, and recent fasting meta-analyses to separate promising findings from exaggerated anti-aging claims. 🔬 What's Covered in This Video • Fasting and longevity: Why the CALERIE calorie-restriction trial found a modest change in DunedinPACE but did not prove intermittent fasting extends human lifespan. • Muscle loss after 40: What a 2026 meta-analysis found about fat-free mass and why losing fat-free mass isn't necessarily the same as losing skeletal muscle. • Resistance training and protein: What eight studies involving 221 participants reveal about fasting, body fat, and preserving lean tissue during exercise. • Healthy aging strategies: Why nutrition, strength, physical function, and sustainable eating habits may matter more than your fasting window. ⏱️ Timestamps 00:00 Fasting After 40 Promise 01:15 Weight Loss Tradeoffs 02:25 CALERIE Aging Signal 04:04 Safety And Caveats 05:58 Muscle Loss Concern 06:54 Why Comparisons Matter 07:19 Resistance Training Evidence 08:11 Protein And Eating Window 08:44 What Headlines Get Wrong 09:31 Practical Takeaways After 40 10:52 Final Verdict And Wrap 📚 Research & Sources 1. Nature Aging (2023) Journal article: Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial https://www.nature.com/articles/s43587-022-00357-y 2. Advances in Nutrition (2026) Journal article: Intermittent Fasting and Fat-Free Mass Outcomes in Middle-Aged and Older Adults: A Scoping Review https://advances.nutrition.org/article/S2161-8313%2826%2900077-3/fullte https://www.youtube-nocookie.com/embed/h64iCzUz5Ho 710 2026-10-10T16:00:23.000Z 2026-10-22T18:54:07.073Z https://longevityharbor.com/de/watch/h64iCzUz5Ho Fasting After 40: Are You Losing the Wrong Weight? https://i.ytimg.com/vi/h64iCzUz5Ho/hqdefault.jpg Intermittent fasting after 40: Does it really slow aging, or could you be losing muscle along with body fat? In this science-based investigation, research scientist Marcus examines the evidence behind fasting, longevity, biological aging, and muscle preservation. Can intermittent fasting help you live longer? What does the research actually say about fat-free mass, resistance training, and healthy aging? We examine the CALERIE trial, the DunedinPACE biological aging measurement, and recent fasting meta-analyses to separate promising findings from exaggerated anti-aging claims. 🔬 What's Covered in This Video • Fasting and longevity: Why the CALERIE calorie-restriction trial found a modest change in DunedinPACE but did not prove intermittent fasting extends human lifespan. • Muscle loss after 40: What a 2026 meta-analysis found about fat-free mass and why losing fat-free mass isn't necessarily the same as losing skeletal muscle. • Resistance training and protein: What eight studies involving 221 participants reveal about fasting, body fat, and preserving lean tissue during exercise. • Healthy aging strategies: Why nutrition, strength, physical function, and sustainable eating habits may matter more than your fasting window. ⏱️ Timestamps 00:00 Fasting After 40 Promise 01:15 Weight Loss Tradeoffs 02:25 CALERIE Aging Signal 04:04 Safety And Caveats 05:58 Muscle Loss Concern 06:54 Why Comparisons Matter 07:19 Resistance Training Evidence 08:11 Protein And Eating Window 08:44 What Headlines Get Wrong 09:31 Practical Takeaways After 40 10:52 Final Verdict And Wrap 📚 Research & Sources 1. Nature Aging (2023) Journal article: Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial https://www.nature.com/articles/s43587-022-00357-y 2. Advances in Nutrition (2026) Journal article: Intermittent Fasting and Fat-Free Mass Outcomes in Middle-Aged and Older Adults: A Scoping Review https://advances.nutrition.org/article/S2161-8313%2826%2900077-3/fullte https://www.youtube-nocookie.com/embed/h64iCzUz5Ho 710 2026-10-10T16:00:23.000Z 2026-10-22T18:54:07.073Z https://longevityharbor.com/en/watch/hEsU0Ueg5g8 Adam Gries on longevity advocacy, health tracking and aging research https://i.ytimg.com/vi/hEsU0Ueg5g8/hqdefault.jpg In this video description, entrepreneur Adam Gries argues that aging is the main risk factor and cause of death, outlines personal tracking steps and existing interventions, and discusses longevity biotech, regulation and influence strategies. The description is a talk outline, not a study. https://www.youtube-nocookie.com/embed/hEsU0Ueg5g8 4917 2026-03-31T06:03:51.000Z 2026-10-23T01:50:11.099Z https://longevityharbor.com/de/watch/hEsU0Ueg5g8 Adam Gries über Longevity-Advocacy, Gesundheitsdaten und Alternsforschung https://i.ytimg.com/vi/hEsU0Ueg5g8/hqdefault.jpg In dieser Videobeschreibung argumentiert der Unternehmer Adam Gries, Altern sei der wichtigste Risikofaktor und die Haupttodesursache; er skizziert persönliche Messschritte und bestehende Interventionen und spricht über Longevity-Biotech, Regulierung und Einflussstrategien. Die Beschreibung ist eine Vortragsgleiderung, keine Studie. https://www.youtube-nocookie.com/embed/hEsU0Ueg5g8 4917 2026-03-31T06:03:51.000Z 2026-10-23T01:50:11.099Z https://longevityharbor.com/en/watch/hF-IjqQoAnE Video description: five breakfast habits after 60 and five protein-rich alternatives https://i.ytimg.com/vi/hF-IjqQoAnE/hqdefault.jpg The description says the video covers five breakfast habits viewers over 60 should reconsider and five protein-rich foods to add, plus why movement matters alongside diet. https://www.youtube-nocookie.com/embed/hF-IjqQoAnE 395 2026-09-22T11:49:44.000Z 2026-10-22T21:58:01.363Z https://longevityharbor.com/de/watch/hF-IjqQoAnE Videobeschreibung: fünf Frühstücksgewohnheiten ab 60 und fünf proteinreiche Alternativen https://i.ytimg.com/vi/hF-IjqQoAnE/hqdefault.jpg Laut Beschreibung behandelt das Video fünf Frühstücksgewohnheiten, die Über-60-Jährige überdenken sollten, und fünf proteinreiche Lebensmittel zum Ergänzen – sowie die Rolle von Bewegung neben der Ernährung. https://www.youtube-nocookie.com/embed/hF-IjqQoAnE 395 2026-09-22T11:49:44.000Z 2026-10-22T21:58:01.363Z https://longevityharbor.com/en/watch/hHBcdKdRnpU NMN A Promising Therapeutic For Age-Related Infertility | Dr Lindsay Wu Ep3 https://i.ytimg.com/vi/hHBcdKdRnpU/hqdefault.jpg Here Dr Wu talks about Dr Wu's experiments with NMN and female age related fertility in mice. Some links are affiliate links so we will earn a commission when they are used to purchase products. *Renue By Science* 10% : Code MHS Use SUBMHS for 15% on subscription orders NMN https://tinyurl.com/3wr8pr3t *ProHealth* 15% discount Code MODERN : http://prohealth.pxf.io/Gm1mKk NMN Pro 1000 https://prohealth.pxf.io/Jz4dL2 Nuchido Time+ 20% discount of first purchase with code MODERN20 https://nuchido.com/MODERN NOVOS Core & Boost https://novos.sjv.io/daqJ0Q code 5OFFMHS ☕If you would like to support our channel, we’d love a coffee…thank you! _https://www.buymeacoffee.com/mhealthspan_ *SiPhox Health* 20 % Code MODERN blood test (only in US & Canada) _https://siphoxhealth.com/discount/modern_ *OmegaQuant* 5% discount Code MODERN _https://omegaquant.com/shop/_ ⏲️Chapters 00:00 Why fertility? 03:50 In vivo results 06:50 IVF use 09:00 Translation Dr Lindsay Wu is an NHMRC Research Fellow and is the Head of the Laboratory for Ageing Research at UNSW Sydney. He has a background in molecular biology, biochemistry and drug development. Dr Wu received his PhD at the Garvin Institute of Medical Research after studying at the University of Sydney. 🌐Links in this video NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063679/ Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14698 Dr Wu's page at UNSW https://www.unsw.edu.au/staff/lindsay-wu *************************************** Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation. Audio Copyright Disclaimer Please note that we have full authorization to the music that we used in our videos as they w https://www.youtube-nocookie.com/embed/hHBcdKdRnpU 597 2023-11-26T12:19:29.000Z 2026-10-22T19:04:42.856Z https://longevityharbor.com/de/watch/hHBcdKdRnpU NMN A Promising Therapeutic For Age-Related Infertility | Dr Lindsay Wu Ep3 https://i.ytimg.com/vi/hHBcdKdRnpU/hqdefault.jpg Here Dr Wu talks about Dr Wu's experiments with NMN and female age related fertility in mice. Some links are affiliate links so we will earn a commission when they are used to purchase products. *Renue By Science* 10% : Code MHS Use SUBMHS for 15% on subscription orders NMN https://tinyurl.com/3wr8pr3t *ProHealth* 15% discount Code MODERN : http://prohealth.pxf.io/Gm1mKk NMN Pro 1000 https://prohealth.pxf.io/Jz4dL2 Nuchido Time+ 20% discount of first purchase with code MODERN20 https://nuchido.com/MODERN NOVOS Core & Boost https://novos.sjv.io/daqJ0Q code 5OFFMHS ☕If you would like to support our channel, we’d love a coffee…thank you! _https://www.buymeacoffee.com/mhealthspan_ *SiPhox Health* 20 % Code MODERN blood test (only in US & Canada) _https://siphoxhealth.com/discount/modern_ *OmegaQuant* 5% discount Code MODERN _https://omegaquant.com/shop/_ ⏲️Chapters 00:00 Why fertility? 03:50 In vivo results 06:50 IVF use 09:00 Translation Dr Lindsay Wu is an NHMRC Research Fellow and is the Head of the Laboratory for Ageing Research at UNSW Sydney. He has a background in molecular biology, biochemistry and drug development. Dr Wu received his PhD at the Garvin Institute of Medical Research after studying at the University of Sydney. 🌐Links in this video NAD+ Repletion Rescues Female Fertility during Reproductive Aging https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063679/ Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14698 Dr Wu's page at UNSW https://www.unsw.edu.au/staff/lindsay-wu *************************************** Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation. Audio Copyright Disclaimer Please note that we have full authorization to the music that we used in our videos as they w https://www.youtube-nocookie.com/embed/hHBcdKdRnpU 597 2023-11-26T12:19:29.000Z 2026-10-22T19:04:42.856Z https://longevityharbor.com/en/watch/hI0IrMWmGd4 Histones & Ageing: Epigenetic Clocks Explained https://i.ytimg.com/vi/hI0IrMWmGd4/hqdefault.jpg Histones are proteins that DNA wraps around — but they’re more than just packaging. They act as switches, controlling which genes turn on or off. Chemical marks on histones (acetylation, methylation, phosphorylation) regulate DNA repair, inflammation, and metabolism. With age, these marks drift, driving epigenetic ageing. Recent research (Nature Reviews Molecular Cell Biology, 2023) shows that reduced histone levels destabilise the genome, leaving DNA prone to damage. Changes like reduced H3K27 trimethylation now form the basis of epigenetic clocks, which measure biological age. #LongevityAustralia #naturalantiaging #doctorsgroup #sciencebasedwellness #organicsupplements #antiagingtips #holistichealth #AustralianHealthBrands #herballongevity #biohackingaustralia #agesmart #naturalyouth #wellnessbackedbyscience #longevitylifestyle #epigenetics #Histones #ageing #EpigeneticClock #DNA #MolecularBiology #youtube #youtubevideos #video https://www.youtube-nocookie.com/embed/hI0IrMWmGd4 162 2025-09-11T11:34:44.000Z 2026-10-22T19:43:51.951Z https://longevityharbor.com/de/watch/hI0IrMWmGd4 Histones & Ageing: Epigenetic Clocks Explained https://i.ytimg.com/vi/hI0IrMWmGd4/hqdefault.jpg Histones are proteins that DNA wraps around — but they’re more than just packaging. They act as switches, controlling which genes turn on or off. Chemical marks on histones (acetylation, methylation, phosphorylation) regulate DNA repair, inflammation, and metabolism. With age, these marks drift, driving epigenetic ageing. Recent research (Nature Reviews Molecular Cell Biology, 2023) shows that reduced histone levels destabilise the genome, leaving DNA prone to damage. Changes like reduced H3K27 trimethylation now form the basis of epigenetic clocks, which measure biological age. #LongevityAustralia #naturalantiaging #doctorsgroup #sciencebasedwellness #organicsupplements #antiagingtips #holistichealth #AustralianHealthBrands #herballongevity #biohackingaustralia #agesmart #naturalyouth #wellnessbackedbyscience #longevitylifestyle #epigenetics #Histones #ageing #EpigeneticClock #DNA #MolecularBiology #youtube #youtubevideos #video https://www.youtube-nocookie.com/embed/hI0IrMWmGd4 162 2025-09-11T11:34:44.000Z 2026-10-22T19:43:51.951Z https://longevityharbor.com/en/watch/hITH7DGbpw4 Video description: fasting timing claims from Dr. David Sinclair's Lifespan episode https://i.ytimg.com/vi/hITH7DGbpw4/hqdefault.jpg The description says Dr. David Sinclair, a Harvard genetics professor, discusses how to fast effectively, what he says happens at the 12-, 24- and 48+-hour marks, plateaus, and considerations for women, men and different life stages. https://www.youtube-nocookie.com/embed/hITH7DGbpw4 4090 2026-07-10T14:44:54.000Z 2026-10-22T23:38:51.034Z https://longevityharbor.com/de/watch/hITH7DGbpw4 Videobeschreibung: Aussagen zum Fasten-Timing aus Dr. David Sinclairs Lifespan-Folge https://i.ytimg.com/vi/hITH7DGbpw4/hqdefault.jpg Laut Beschreibung erläutert Dr. David Sinclair, Genetikprofessor in Harvard, wie man wirksam fastet, was nach seinen Angaben nach 12, 24 und 48+ Stunden geschieht, Plateaus sowie Aspekte für Frauen, Männer und verschiedene Lebensphasen. https://www.youtube-nocookie.com/embed/hITH7DGbpw4 4090 2026-07-10T14:44:54.000Z 2026-10-22T23:38:51.034Z https://longevityharbor.com/en/watch/hIeDqdsDaTg 7 Scientifically Proven Exercises to Reverse Aging & Stay Young! #PowerMax #FITFORLIFE #Fitness https://i.ytimg.com/vi/hIeDqdsDaTg/hqdefault.jpg Discover the 7 Scientifically Proven Exercises to Reverse Aging & Stay Young! In this video, we dive into exercises backed by research that can help slow down the aging process, improve flexibility, boost muscle strength, and enhance overall vitality. Whether you're looking to maintain youthfulness or improve longevity, these exercises are a must-try! Don’t forget to subscribe for more fitness and wellness tips! #ReverseAging #StayYoung #AntiAgingExercises #PowerMax #FitnessTips #HealthyAging #Longevity #ExerciseForLife #YouthfulLiving #ScientificallyProven #WellnessJourney #StrengthTraining #CardioFitness #HealthyLifestyle #FITFORLIFE Call us at - +918080269269 OR For more details please click on the link below; Website- https://www.powermaxfitness.net/ Instagram- https://www.instagram.com/powermaxfitness/ Facebook- https://www.facebook.com/powermaxindia/ Twitter- https://twitter.com/powermax_india Linkedin- https://in.linkedin.com/company/powermaxfitness Quora- https://www.quora.com/profile/Powermax-Fitness-8?q=powerma https://www.youtube-nocookie.com/embed/hIeDqdsDaTg 307 2024-10-24T10:56:00.000Z 2026-10-22T18:54:05.966Z https://longevityharbor.com/de/watch/hIeDqdsDaTg 7 Scientifically Proven Exercises to Reverse Aging & Stay Young! #PowerMax #FITFORLIFE #Fitness https://i.ytimg.com/vi/hIeDqdsDaTg/hqdefault.jpg Discover the 7 Scientifically Proven Exercises to Reverse Aging & Stay Young! In this video, we dive into exercises backed by research that can help slow down the aging process, improve flexibility, boost muscle strength, and enhance overall vitality. Whether you're looking to maintain youthfulness or improve longevity, these exercises are a must-try! Don’t forget to subscribe for more fitness and wellness tips! #ReverseAging #StayYoung #AntiAgingExercises #PowerMax #FitnessTips #HealthyAging #Longevity #ExerciseForLife #YouthfulLiving #ScientificallyProven #WellnessJourney #StrengthTraining #CardioFitness #HealthyLifestyle #FITFORLIFE Call us at - +918080269269 OR For more details please click on the link below; Website- https://www.powermaxfitness.net/ Instagram- https://www.instagram.com/powermaxfitness/ Facebook- https://www.facebook.com/powermaxindia/ Twitter- https://twitter.com/powermax_india Linkedin- https://in.linkedin.com/company/powermaxfitness Quora- https://www.quora.com/profile/Powermax-Fitness-8?q=powerma https://www.youtube-nocookie.com/embed/hIeDqdsDaTg 307 2024-10-24T10:56:00.000Z 2026-10-22T18:54:05.966Z https://longevityharbor.com/en/watch/hVdY6bgYyLs Video description: Longo on fasting, nutrition and the body's repair processes https://i.ytimg.com/vi/hVdY6bgYyLs/hqdefault.jpg The description says Professor Valter Longo's interest in aging and longevity grew from early calorie-restriction research at UCLA, and it asks how fasting and nutrition might activate the body's natural repair processes. It gives no results. https://www.youtube-nocookie.com/embed/hVdY6bgYyLs 103 2026-09-29T12:00:20.000Z 2026-10-22T21:38:54.681Z https://longevityharbor.com/de/watch/hVdY6bgYyLs Videobeschreibung: Longo über Fasten, Ernährung und Selbstreparatur des Körpers https://i.ytimg.com/vi/hVdY6bgYyLs/hqdefault.jpg Laut Beschreibung entstand Professor Valter Longos Interesse an Altern und Langlebigkeit aus früher Kalorienrestriktionsforschung an der UCLA; zudem fragt sie, wie Fasten und Ernährung die natürlichen Reparaturprozesse des Körpers aktivieren könnten. Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/hVdY6bgYyLs 103 2026-09-29T12:00:20.000Z 2026-10-22T21:38:54.681Z https://longevityharbor.com/en/watch/h_-_rFXcBIA Your Immune Age vs Your Real Age – They're Not the Same: Dr Yurth https://i.ytimg.com/vi/h_-_rFXcBIA/hqdefault.jpg The how and why of the Aging Immune System with 👉 Gain FREE access to my exclusive 'Longevity Cheat Sheet'? Subscribe to my weekly newsletter https://www.lisatamati.com/lisa/ Shop our science backed longevity, Immune, gut and cellular health formulation "Rejuvenate Pro" by Aevum Labs. https://shop.lisatamati.com/pages/rej... Understanding the Aging Immune System with Dr. Elizabeth Yurth & Lisa Tamati | How Rejuvenate Pro Targets Immunosenescence In this powerful practitioner-focused discussion, Dr. Elizabeth Yurth, longevity and regenerative medicine expert, joins Lisa Tamati, health optimization coach and founder of Aevum Labs, to explore one of the most critical — yet often overlooked — drivers of aging: the immune system. We break down: What happens to your immune system as you age — including thymic involution, reduced naïve T cells, and dysregulated inflammatory responses How immunosenescence drives vulnerability to infections, pathogens, autoimmunity, and cancer The immune system’s deep connection to gut health and neurological degeneration 🔥 The role of inflammaging and how chronic low-grade inflammation accelerates all 12 hallmarks of aging You'll also discover how our flagship formulation, Rejuvenate Pro, is scientifically designed to counter the immune system’s decline. We explain how its unique combination of: Immune Defense Proteins (IDP®) Immunel® colostrum extract 20% carnosic acid (from rosemary) Kawakawa (NZ native plant) works synergistically to: Restore gut barrier integrity Reduce inflammatory cytokines and chemokines Support immune modulation and tissue repair Enhance overall immune resilience and longevity This is a must-watch for clinicians, biohackers, and anyone invested in extending healthspan through immune rejuvenation. 🔗 Learn more at: https://www.aevumlabs.co.nz 📦 Order Rejuvenate Pro: https://shop.lisatamati.com/pages/rejuvenate V I D E O S T O W A T C H N E X T : --------------------------------- https://www.youtube-nocookie.com/embed/h_-_rFXcBIA 4494 2025-07-24T00:00:45.000Z 2026-10-22T19:32:33.340Z https://longevityharbor.com/de/watch/h_-_rFXcBIA Your Immune Age vs Your Real Age – They're Not the Same: Dr Yurth https://i.ytimg.com/vi/h_-_rFXcBIA/hqdefault.jpg The how and why of the Aging Immune System with 👉 Gain FREE access to my exclusive 'Longevity Cheat Sheet'? Subscribe to my weekly newsletter https://www.lisatamati.com/lisa/ Shop our science backed longevity, Immune, gut and cellular health formulation "Rejuvenate Pro" by Aevum Labs. https://shop.lisatamati.com/pages/rej... Understanding the Aging Immune System with Dr. Elizabeth Yurth & Lisa Tamati | How Rejuvenate Pro Targets Immunosenescence In this powerful practitioner-focused discussion, Dr. Elizabeth Yurth, longevity and regenerative medicine expert, joins Lisa Tamati, health optimization coach and founder of Aevum Labs, to explore one of the most critical — yet often overlooked — drivers of aging: the immune system. We break down: What happens to your immune system as you age — including thymic involution, reduced naïve T cells, and dysregulated inflammatory responses How immunosenescence drives vulnerability to infections, pathogens, autoimmunity, and cancer The immune system’s deep connection to gut health and neurological degeneration 🔥 The role of inflammaging and how chronic low-grade inflammation accelerates all 12 hallmarks of aging You'll also discover how our flagship formulation, Rejuvenate Pro, is scientifically designed to counter the immune system’s decline. We explain how its unique combination of: Immune Defense Proteins (IDP®) Immunel® colostrum extract 20% carnosic acid (from rosemary) Kawakawa (NZ native plant) works synergistically to: Restore gut barrier integrity Reduce inflammatory cytokines and chemokines Support immune modulation and tissue repair Enhance overall immune resilience and longevity This is a must-watch for clinicians, biohackers, and anyone invested in extending healthspan through immune rejuvenation. 🔗 Learn more at: https://www.aevumlabs.co.nz 📦 Order Rejuvenate Pro: https://shop.lisatamati.com/pages/rejuvenate V I D E O S T O W A T C H N E X T : --------------------------------- https://www.youtube-nocookie.com/embed/h_-_rFXcBIA 4494 2025-07-24T00:00:45.000Z 2026-10-22T19:32:33.340Z https://longevityharbor.com/en/watch/hcIaG0RRzDw Video description: five exercise approaches for adults over 70 to support strength and balance https://i.ytimg.com/vi/hcIaG0RRzDw/hqdefault.jpg A video description presents five exercise approaches aimed at adults over 70, said to support muscle strength, balance, coordination and everyday mobility. It offers no study data, numbers or results; all statements are the creator's description of the video's content. https://www.youtube-nocookie.com/embed/hcIaG0RRzDw 1697 2026-10-21T16:58:23.000Z 2026-10-22T19:48:01.754Z https://longevityharbor.com/de/watch/hcIaG0RRzDw Videobeschreibung: fünf Übungsansätze für Erwachsene über 70 für Kraft und Gleichgewicht https://i.ytimg.com/vi/hcIaG0RRzDw/hqdefault.jpg Eine Videobeschreibung stellt fünf Übungsansätze für Erwachsene über 70 vor, die Muskelkraft, Gleichgewicht, Koordination und Alltagsmobilität unterstützen sollen. Sie enthält keine Studiendaten, Zahlen oder Ergebnisse; alle Aussagen sind die Beschreibung des Erstellers zum Videoinhalt. https://www.youtube-nocookie.com/embed/hcIaG0RRzDw 1697 2026-10-21T16:58:23.000Z 2026-10-22T19:48:01.754Z https://longevityharbor.com/en/watch/hcgr9ZHPGoE Naked Mole Rats' Secret: Unlocking Human Longevity! #shorts https://i.ytimg.com/vi/hcgr9ZHPGoE/hqdefault.jpg Unlock the secrets of youth! Three key factors impact aging: mTOR pathway, telomere attrition, and sirtuins. Discover how these guardians of the genome impact your health and longevity. #AntiAging #Longevity #mTOR #Telomeres #Sirtuins #Genome https://www.youtube-nocookie.com/embed/hcgr9ZHPGoE 177 2025-10-28T23:13:39.000Z 2026-10-22T19:54:21.377Z https://longevityharbor.com/de/watch/hcgr9ZHPGoE Naked Mole Rats' Secret: Unlocking Human Longevity! #shorts https://i.ytimg.com/vi/hcgr9ZHPGoE/hqdefault.jpg Unlock the secrets of youth! Three key factors impact aging: mTOR pathway, telomere attrition, and sirtuins. Discover how these guardians of the genome impact your health and longevity. #AntiAging #Longevity #mTOR #Telomeres #Sirtuins #Genome https://www.youtube-nocookie.com/embed/hcgr9ZHPGoE 177 2025-10-28T23:13:39.000Z 2026-10-22T19:54:21.377Z https://longevityharbor.com/en/watch/hiX7c690JN0 Video description on NAD+, NMN and NR in longevity research https://i.ytimg.com/vi/hiX7c690JN0/hqdefault.jpg The description presents a video about NAD+, its reported decline with age, sirtuins and David Sinclair's Harvard research, and asks whether NR or NMN works, citing 2025/2026 studies and a supplement-market warning. These are the creator's claims; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/hiX7c690JN0 471 2026-07-30T17:00:14.000Z 2026-10-23T01:19:35.274Z https://longevityharbor.com/de/watch/hiX7c690JN0 Videobeschreibung zu NAD+, NMN und NR in der Langlebigkeitsforschung https://i.ytimg.com/vi/hiX7c690JN0/hqdefault.jpg Die Beschreibung stellt ein Video über NAD+, dessen berichteten Rückgang mit dem Alter, Sirtuine und David Sinclairs Harvard-Forschung vor und fragt, ob NR oder NMN wirkt; sie nennt Studien aus 2025/2026 und eine Warnung zum Supplementmarkt. Das sind Angaben des Erstellers; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/hiX7c690JN0 471 2026-07-30T17:00:14.000Z 2026-10-23T01:19:35.274Z https://longevityharbor.com/en/watch/hkGGt-vE-8A What does DNA methylation tell us about aging? | Prof.Nir Eynon&Dr.Raghav Sehgal&Dr.Macsue Jacques https://i.ytimg.com/vi/hkGGt-vE-8A/hqdefault.jpg Is your biological age telling a different story than your birth certificate? In this episode of Decoding Longevity, we explore the fascinating world of the ageing methylome. Join hosts Raghav Sehgal and Macsue Jacques in a deep conversation with Professor Nir Eynon—Group Leader at Monash University and co-author of "Making Sense of the Ageing Methylome"—as we unravel what DNA methylation patterns reveal about how we age. 💡 Topics we cover: • What is the methylome, and how is it linked to aging? • How epigenetic clocks work—and what they can (and can't) tell us • Can exercise slow biological aging by changing methylation? • Why DNA methylation variability might explain age-related diseases • Entropy, tissue specificity, and the future of personalized aging clocks 🧬 Whether you're a longevity researcher or just longevity-curious, this episode breaks down complex science into insights that matter. 🎙️ *Based on the paper: “Making Sense of the Ageing Methylome” (Nature Reviews Genetics, 2022)* 🔗 Subscribe and follow for more episodes breaking down the science of aging 🔵 Spotify: https://open.spotify.com/episode/4jRYqjojPeAErWY56lQdns?si=r-PsNZPBSCSU43jwUdp9vQ 🔵 IG: https://www.instagram.com/decodinglongevity/ 🔵 LinkedIn: https://www.linkedin.com/company/decoding-longevity/ 🔵 Bluesky: https://bsky.app/profile/decodinglongevity.bsky.social 🔵 X: https://x.com/DcodLongevity https://www.youtube-nocookie.com/embed/hkGGt-vE-8A 1244 2025-05-07T15:15:13.000Z 2026-10-22T19:21:27.534Z https://longevityharbor.com/de/watch/hkGGt-vE-8A What does DNA methylation tell us about aging? | Prof.Nir Eynon&Dr.Raghav Sehgal&Dr.Macsue Jacques https://i.ytimg.com/vi/hkGGt-vE-8A/hqdefault.jpg Is your biological age telling a different story than your birth certificate? In this episode of Decoding Longevity, we explore the fascinating world of the ageing methylome. Join hosts Raghav Sehgal and Macsue Jacques in a deep conversation with Professor Nir Eynon—Group Leader at Monash University and co-author of "Making Sense of the Ageing Methylome"—as we unravel what DNA methylation patterns reveal about how we age. 💡 Topics we cover: • What is the methylome, and how is it linked to aging? • How epigenetic clocks work—and what they can (and can't) tell us • Can exercise slow biological aging by changing methylation? • Why DNA methylation variability might explain age-related diseases • Entropy, tissue specificity, and the future of personalized aging clocks 🧬 Whether you're a longevity researcher or just longevity-curious, this episode breaks down complex science into insights that matter. 🎙️ *Based on the paper: “Making Sense of the Ageing Methylome” (Nature Reviews Genetics, 2022)* 🔗 Subscribe and follow for more episodes breaking down the science of aging 🔵 Spotify: https://open.spotify.com/episode/4jRYqjojPeAErWY56lQdns?si=r-PsNZPBSCSU43jwUdp9vQ 🔵 IG: https://www.instagram.com/decodinglongevity/ 🔵 LinkedIn: https://www.linkedin.com/company/decoding-longevity/ 🔵 Bluesky: https://bsky.app/profile/decodinglongevity.bsky.social 🔵 X: https://x.com/DcodLongevity https://www.youtube-nocookie.com/embed/hkGGt-vE-8A 1244 2025-05-07T15:15:13.000Z 2026-10-22T19:21:27.534Z https://longevityharbor.com/en/watch/hnPB_4_tico Horvath Clock described: DNA methylation and biological age https://i.ytimg.com/vi/hnPB_4_tico/hqdefault.jpg The description presents the Horvath Clock, published in 2013, as an epigenetic clock built from DNA methylation data across 51 tissue types and thousands of people, tracking biological age with an average error of 3.6 years. It also says partial epigenetic reprogramming aims to reset the cellular clock. https://www.youtube-nocookie.com/embed/hnPB_4_tico 235 2026-03-24T11:35:24.000Z 2026-10-23T01:57:47.005Z https://longevityharbor.com/de/watch/hnPB_4_tico Horvath-Uhr beschrieben: DNA-Methylierung und biologisches Alter https://i.ytimg.com/vi/hnPB_4_tico/hqdefault.jpg Die Beschreibung stellt die Horvath-Uhr, veröffentlicht 2013, als epigenetische Uhr vor, die aus DNA-Methylierungsdaten von 51 Gewebearten und Tausenden Menschen gebaut wurde und das biologische Alter mit einem mittleren Fehler von 3,6 Jahren erfasst. Zudem heißt es, partielle epigenetische Reprogrammierung solle die zelluläre Uhr zurücksetzen. https://www.youtube-nocookie.com/embed/hnPB_4_tico 235 2026-03-24T11:35:24.000Z 2026-10-23T01:57:47.005Z https://longevityharbor.com/en/watch/hqgi56RGV9U Creator's review of 50+ intermittent fasting studies: window vs. calories https://i.ytimg.com/vi/hqgi56RGV9U/hqdefault.jpg The creator says intermittent fasting helps mainly by reducing how much people eat, not through a special metabolic effect of the eating window; anti-ageing claims rest mostly on mice, and the death-scare headline was never peer-reviewed. https://www.youtube-nocookie.com/embed/hqgi56RGV9U 102 2026-04-26T03:52:36.000Z 2026-10-23T01:20:26.012Z https://longevityharbor.com/de/watch/hqgi56RGV9U Review des Erstellers zu über 50 Intervallfasten-Studien: Zeitfenster vs. Kalorien https://i.ytimg.com/vi/hqgi56RGV9U/hqdefault.jpg Laut dem Ersteller hilft Intervallfasten vor allem dadurch, dass Menschen weniger essen, nicht durch einen besonderen Stoffwechseleffekt des Essensfensters; Anti-Aging-Behauptungen stützen sich überwiegend auf Mäuse, und die Schlagzeile zur Sterblichkeit war nie begutachtet. https://www.youtube-nocookie.com/embed/hqgi56RGV9U 102 2026-04-26T03:52:36.000Z 2026-10-23T01:20:26.012Z https://longevityharbor.com/en/watch/huZevdTEhXY Talk on rapamycin, mTOR inhibition and DNA damage in the ageing immune system https://i.ytimg.com/vi/huZevdTEhXY/hqdefault.jpg In this talk description, Loren Kell presents four years of work including laboratory assays and a clinical trial in older adults on whether low-dose mTOR inhibitors such as rapamycin reduce DNA damage and senescence markers in the ageing immune system. The description reports reduced DNA lesions, suppressed senescence markers and improved immune cell survival; these are described results, not established human benefits. https://www.youtube-nocookie.com/embed/huZevdTEhXY 996 2025-12-02T15:38:43.000Z 2026-10-23T03:22:41.365Z https://longevityharbor.com/de/watch/huZevdTEhXY Vortrag über Rapamycin, mTOR-Hemmung und DNA-Schäden im alternden Immunsystem https://i.ytimg.com/vi/huZevdTEhXY/hqdefault.jpg In dieser Vortragsbeschreibung stellt Loren Kell vier Jahre Arbeit vor, darunter Laboruntersuchungen und eine klinische Studie mit älteren Erwachsenen, dazu, ob niedrig dosierte mTOR-Hemmer wie Rapamycin DNA-Schäden und Seneszenzmarker im alternden Immunsystem verringern. Die Beschreibung berichtet von weniger DNA-Läsionen, unterdrückten Seneszenzmarkern und besserem Überleben von Immunzellen; dies sind beschriebene Ergebnisse, keine belegten Nutzen für Menschen. https://www.youtube-nocookie.com/embed/huZevdTEhXY 996 2025-12-02T15:38:43.000Z 2026-10-23T03:22:41.365Z https://longevityharbor.com/en/watch/huq_z9QkM_I Podcast description: rapamycin and Alzheimer's research in animals https://i.ytimg.com/vi/huq_z9QkM_I/hqdefault.jpg The description presents Galvan's view that aging is the biggest Alzheimer's risk factor and that rapamycin restored brain damage in animal studies; human trials are described as overdue, not done. https://www.youtube-nocookie.com/embed/huq_z9QkM_I 4266 2026-09-03T16:00:35.000Z 2026-10-22T22:30:33.637Z https://longevityharbor.com/de/watch/huq_z9QkM_I Podcast-Beschreibung: Rapamycin und Alzheimer-Forschung im Tier https://i.ytimg.com/vi/huq_z9QkM_I/hqdefault.jpg Die Beschreibung gibt Galvans Sicht wieder, dass Altern der größte Alzheimer-Risikofaktor sei und Rapamycin in Tierstudien Hirnschäden rückgängig gemacht habe; Humanstudien werden als überfällig, nicht als durchgeführt beschrieben. https://www.youtube-nocookie.com/embed/huq_z9QkM_I 4266 2026-09-03T16:00:35.000Z 2026-10-22T22:30:33.637Z https://longevityharbor.com/en/watch/hxQ5TzZW4cQ Geroscience: The Biology of Aging @ Oxford (Lord Florey Lecture by Sebastian A. Brunemeier) https://i.ytimg.com/vi/hxQ5TzZW4cQ/hqdefault.jpg Sebastian Aguiar Brunemeier, geroscientist and Principal at Apollo Ventures, delivers the Lord Florey Lecture at Lincoln College, Oxford in November 2018. Sebastian Aguiar was a Clarendon Scholar at Lincoln College, Oxford for his DPhil (PhD) on the biochemistry of aging. 0:10 Introduction: The Geroscience Revolution Parallels to the Antibiotic Revolution, Lord Howard Florey, and leading causes of death over the last century. 4:47 Part 1: Aging Demographics and the Silver Tsunami 9:20 Part 2: Extending 'Healthspan' Supercentenarians, the Hallmarks of Aging, Google Calico, Apollo Ventures, Juvenescence, Unity Biotech, NIH Geroscience Interest Group, squaring the mortality curve 17:00 Part 3: Geroscience Case Studies: Examples of Healthspan Extension from the Lab. Heterochronic Parabiosis, Cellular Senescence, Telomerase Gene Therapy, Caloric Restriction Mimetics, Rapamycin/Rapalogs, Metformin (TAME), Autophagy enhancement. 27:40 Part 4: Conclusion -- The Holy Grail: Harnessing Germline Immortality. Prospects for the future & Apollo Ventures portfolio companies. — The Florey Lecture is named after Lord Howard Florey, an Australian pharmacologist and pathologist who shared the Nobel Prize in Physiology or Medicine in 1945 with Sir Ernst Boris Chain and Sir Alexander Fleming for his role in the development of penicillin. Although Fleming received most of the credit for the discovery of penicillin, it was Florey who carried out the first ever clinical trials in 1941 of penicillin at the Radcliffe Infirmary in Oxford on the first patient, a postmaster from Wolvercote near Oxford. It was Florey and Chain who actually made a useful and effective drug out of penicillin, after the task had been abandoned as too difficult. Florey's discoveries, along with Alexander Fleming and Ernst Chain, are estimated to have saved over 82 million lives, and he is consequently regarded by the Australian scientific and medical community as one of its greatest figures. Sir Robert Menzies, Australia's longest-serving Prime https://www.youtube-nocookie.com/embed/hxQ5TzZW4cQ 2178 2019-01-23T23:16:56.000Z 2026-10-22T17:43:40.193Z https://longevityharbor.com/de/watch/hxQ5TzZW4cQ Geroscience: The Biology of Aging @ Oxford (Lord Florey Lecture by Sebastian A. Brunemeier) https://i.ytimg.com/vi/hxQ5TzZW4cQ/hqdefault.jpg Sebastian Aguiar Brunemeier, geroscientist and Principal at Apollo Ventures, delivers the Lord Florey Lecture at Lincoln College, Oxford in November 2018. Sebastian Aguiar was a Clarendon Scholar at Lincoln College, Oxford for his DPhil (PhD) on the biochemistry of aging. 0:10 Introduction: The Geroscience Revolution Parallels to the Antibiotic Revolution, Lord Howard Florey, and leading causes of death over the last century. 4:47 Part 1: Aging Demographics and the Silver Tsunami 9:20 Part 2: Extending 'Healthspan' Supercentenarians, the Hallmarks of Aging, Google Calico, Apollo Ventures, Juvenescence, Unity Biotech, NIH Geroscience Interest Group, squaring the mortality curve 17:00 Part 3: Geroscience Case Studies: Examples of Healthspan Extension from the Lab. Heterochronic Parabiosis, Cellular Senescence, Telomerase Gene Therapy, Caloric Restriction Mimetics, Rapamycin/Rapalogs, Metformin (TAME), Autophagy enhancement. 27:40 Part 4: Conclusion -- The Holy Grail: Harnessing Germline Immortality. Prospects for the future & Apollo Ventures portfolio companies. — The Florey Lecture is named after Lord Howard Florey, an Australian pharmacologist and pathologist who shared the Nobel Prize in Physiology or Medicine in 1945 with Sir Ernst Boris Chain and Sir Alexander Fleming for his role in the development of penicillin. Although Fleming received most of the credit for the discovery of penicillin, it was Florey who carried out the first ever clinical trials in 1941 of penicillin at the Radcliffe Infirmary in Oxford on the first patient, a postmaster from Wolvercote near Oxford. It was Florey and Chain who actually made a useful and effective drug out of penicillin, after the task had been abandoned as too difficult. Florey's discoveries, along with Alexander Fleming and Ernst Chain, are estimated to have saved over 82 million lives, and he is consequently regarded by the Australian scientific and medical community as one of its greatest figures. Sir Robert Menzies, Australia's longest-serving Prime https://www.youtube-nocookie.com/embed/hxQ5TzZW4cQ 2178 2019-01-23T23:16:56.000Z 2026-10-22T17:43:40.193Z https://longevityharbor.com/en/watch/hySlWn0f9m8 Prof Matt Kaeberlein: Beyond the Hallmarks: What are we missing in ageing research? https://i.ytimg.com/vi/hySlWn0f9m8/hqdefault.jpg Chaired by Prof Brian Kennedy, Assoc Prof Jan Gruber and Dr Maximilian Unfried, this pioneering Global Conference on Gerophysics (GCGP), 5 - 6 March 2025 will bring together leading theoretical physicists and eminent researchers in ageing and rejuvenation biology to explore a transformative new field: ‘Gerophysics’. Organised by the Healthy Longevity Translational Research Programme at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), this interdisciplinary meeting will investigate the application of rigorous physical principles to unravel the complexities of the ageing process. https://www.youtube-nocookie.com/embed/hySlWn0f9m8 1758 2025-04-14T08:06:03.000Z 2026-10-22T21:14:53.548Z https://longevityharbor.com/de/watch/hySlWn0f9m8 Prof Matt Kaeberlein: Beyond the Hallmarks: What are we missing in ageing research? https://i.ytimg.com/vi/hySlWn0f9m8/hqdefault.jpg Chaired by Prof Brian Kennedy, Assoc Prof Jan Gruber and Dr Maximilian Unfried, this pioneering Global Conference on Gerophysics (GCGP), 5 - 6 March 2025 will bring together leading theoretical physicists and eminent researchers in ageing and rejuvenation biology to explore a transformative new field: ‘Gerophysics’. Organised by the Healthy Longevity Translational Research Programme at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), this interdisciplinary meeting will investigate the application of rigorous physical principles to unravel the complexities of the ageing process. https://www.youtube-nocookie.com/embed/hySlWn0f9m8 1758 2025-04-14T08:06:03.000Z 2026-10-22T21:14:53.548Z https://longevityharbor.com/en/watch/hzQyuOJcUKU Podcast: Physiotherapist Andreas Delaere on Strength Training for Healthy Aging https://i.ytimg.com/vi/hzQyuOJcUKU/hqdefault.jpg In this podcast description, physiotherapist and researcher Andreas Delaere is presented as discussing prevention, strength and power training for older adults, sarcopenia, sleep and adherence; the description reports no study results. https://www.youtube-nocookie.com/embed/hzQyuOJcUKU 3993 2026-04-01T22:00:50.000Z 2026-10-23T01:49:22.260Z https://longevityharbor.com/de/watch/hzQyuOJcUKU Podcast: Physiotherapeut Andreas Delaere über Krafttraining für gesundes Altern https://i.ytimg.com/vi/hzQyuOJcUKU/hqdefault.jpg In dieser Podcast-Beschreibung wird der Physiotherapeut und Forscher Andreas Delaere so vorgestellt, dass er Prävention, Kraft- und Schnellkrafttraining für ältere Menschen, Sarkopenie, Schlaf und Adhärenz bespricht; Studienergebnisse nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/hzQyuOJcUKU 3993 2026-04-01T22:00:50.000Z 2026-10-23T01:49:22.260Z https://longevityharbor.com/en/watch/i--bt1Xz3NA Rapamycin’s Anti-Alzheimer’s Promise: An Autophagy Story https://i.ytimg.com/vi/i--bt1Xz3NA/hqdefault.jpg *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]* Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST* 1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender 0:00 - Introduction 0:30 - Rapamycin's Proposed Anti-Alzheimer's Effects 3:05 - Does Rapamycin work on Alzheimer's Disease? 5:31 - How does Rapamycin achieve these effects? 8:01 - Take-aways 9:05 - Why is autophagy also increased in Alzheimer's Disease? 10:22 - A Twist to the Story... References [Study 355] Kaeberlein M, Galvan V. Rapamycin and Alzheimer's disease: Time for a clinical trial?. Sci Transl Med. 2019;11(476):eaar4289. doi:10.1126/scitranslmed.aar4289 Funding/Conflicts: Public Funding [University of Washington, National Institute of Health] // Potential Conflicts of Interest [Scientific Advising for Resterobio Inc.] [Study 356] Hou SJ, Zhang SX, Li Y, Xu SY. Rapamycin Responds to Alzheimer's Disease: A Potential Translational Therapy. Clin Interv Aging. 2023;18:1629-1639. Published 2023 Oct 2. doi:10.2147/CIA.S429440 Funding/Conflicts: Public Funding [Shanxi Provincial Health Commission, Doctoral Fund] // No Potential Conflicts of Interest [Study 357] Wang H, Fu J, Xu X, Yang Z, Zhang T. Rapamycin Activates Mitophagy and Alleviates Cognitive and Synaptic Plasticity Deficits in a Mouse Model of Alzheimer's Disease. J Gerontol A Biol Sci Med Sci. 2021;76(10):1707-1713. doi:10.1093/gerona/glab142 Funding/Conflicts: Public Funding [National Natural Science Foundation of China] // No Conflicts of Interest ********CRITIQUES, RULES, AND NOTES******** Be aware of the following rules before posting comments: - Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote https://www.youtube-nocookie.com/embed/i--bt1Xz3NA 670 2024-11-18T13:01:01.000Z 2026-10-22T19:04:39.875Z https://longevityharbor.com/de/watch/i--bt1Xz3NA Rapamycin’s Anti-Alzheimer’s Promise: An Autophagy Story https://i.ytimg.com/vi/i--bt1Xz3NA/hqdefault.jpg *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]* Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST* 1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender 0:00 - Introduction 0:30 - Rapamycin's Proposed Anti-Alzheimer's Effects 3:05 - Does Rapamycin work on Alzheimer's Disease? 5:31 - How does Rapamycin achieve these effects? 8:01 - Take-aways 9:05 - Why is autophagy also increased in Alzheimer's Disease? 10:22 - A Twist to the Story... References [Study 355] Kaeberlein M, Galvan V. Rapamycin and Alzheimer's disease: Time for a clinical trial?. Sci Transl Med. 2019;11(476):eaar4289. doi:10.1126/scitranslmed.aar4289 Funding/Conflicts: Public Funding [University of Washington, National Institute of Health] // Potential Conflicts of Interest [Scientific Advising for Resterobio Inc.] [Study 356] Hou SJ, Zhang SX, Li Y, Xu SY. Rapamycin Responds to Alzheimer's Disease: A Potential Translational Therapy. Clin Interv Aging. 2023;18:1629-1639. Published 2023 Oct 2. doi:10.2147/CIA.S429440 Funding/Conflicts: Public Funding [Shanxi Provincial Health Commission, Doctoral Fund] // No Potential Conflicts of Interest [Study 357] Wang H, Fu J, Xu X, Yang Z, Zhang T. Rapamycin Activates Mitophagy and Alleviates Cognitive and Synaptic Plasticity Deficits in a Mouse Model of Alzheimer's Disease. J Gerontol A Biol Sci Med Sci. 2021;76(10):1707-1713. doi:10.1093/gerona/glab142 Funding/Conflicts: Public Funding [National Natural Science Foundation of China] // No Conflicts of Interest ********CRITIQUES, RULES, AND NOTES******** Be aware of the following rules before posting comments: - Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote https://www.youtube-nocookie.com/embed/i--bt1Xz3NA 670 2024-11-18T13:01:01.000Z 2026-10-22T19:04:39.875Z https://longevityharbor.com/en/watch/i33jpTC0oVE Biological age and epigenetic clocks: an AI-narrated explainer https://i.ytimg.com/vi/i33jpTC0oVE/hqdefault.jpg The description says this AI-narrated video explains how epigenetic clocks estimate biological age from DNA methylation patterns and why biological age matters in longevity research. It names sleep, activity, nutrition and stress management as consistently associated with healthier aging patterns, without giving results. https://www.youtube-nocookie.com/embed/i33jpTC0oVE 348 2026-03-11T23:06:05.000Z 2026-10-23T02:09:41.665Z https://longevityharbor.com/de/watch/i33jpTC0oVE Biologisches Alter und epigenetische Uhren: ein KI-narratives Erklärvideo https://i.ytimg.com/vi/i33jpTC0oVE/hqdefault.jpg Laut Beschreibung erklärt dieses KI-narrierte Video, wie epigenetische Uhren das biologische Alter anhand von DNA-Methylierungsmustern schätzen und warum biologisches Alter in der Langlebigkeitsforschung wichtig ist. Schlaf, Bewegung, Ernährung und Stressmanagement werden als durchgängig mit gesünderen Alterungsmustern assoziiert genannt, ohne Ergebnisse zu nennen. https://www.youtube-nocookie.com/embed/i33jpTC0oVE 348 2026-03-11T23:06:05.000Z 2026-10-23T02:09:41.665Z https://longevityharbor.com/en/watch/i3BdBMjcSB4 Video description: strength after 60 and habits that may support it https://i.ytimg.com/vi/i3BdBMjcSB4/hqdefault.jpg This video description says the video explains research on strength after 60 and safety-first habits for activity, strength and mobility. It lists sources but reports no results, numbers or study details. https://www.youtube-nocookie.com/embed/i3BdBMjcSB4 748 2026-10-22T17:00:05.000Z 2026-10-22T19:45:23.977Z https://longevityharbor.com/de/watch/i3BdBMjcSB4 Videobeschreibung: Kraft nach 60 und Gewohnheiten, die sie unterstützen könnten https://i.ytimg.com/vi/i3BdBMjcSB4/hqdefault.jpg Diese Videobeschreibung sagt, das Video erkläre Forschung zu Kraft nach 60 und sicherheitsorientierte Gewohnheiten für Aktivität, Kraft und Mobilität. Sie nennt Quellen, aber keine Ergebnisse, Zahlen oder Studiendetails. https://www.youtube-nocookie.com/embed/i3BdBMjcSB4 748 2026-10-22T17:00:05.000Z 2026-10-22T19:45:23.977Z https://longevityharbor.com/en/watch/i65uno_HZQo The Science of Longevity: Neal Mercado on Ageing Better, Not Just Longer https://i.ytimg.com/vi/i65uno_HZQo/hqdefault.jpg If you have come across the longevity bible by Professor David Sinclair, Lifespan, Why we age and Why we don’t have to, you will know that the real goal is expanding our health and vitality for longer. I talk about this a lot on the show as do many of my guests and experts. I’m joined today by Neal Mercado, the Chief Science Officer at Melrose, one of Australia’s leading wellness brands. Neal brings extensive expertise in product formulation and clinical research and most recently advised on the creation of FUTURELAB, a range dedicated to the science of ageing well. With a background in pharmaceutical sciences and over 15 years of experience in developing innovative wellness products, Neal will answer the many questions on the hallmarks of ageing. In this conversation he also shares the meticulous research and insights of the breakthroughs in cellular wellness that will shape the future of ageing. Here’s the good news, the future of ageing looks bright for those looking to extend not just their lifespan, but their health span and longevity- ensuring we live our best, healthiest years for as long as possible. In this conversation with Neal, I explore the latest ingredients, technology and future of ageing better than at any other time in history. This episode is in partnership with Melrose Futurelab, our season sponsor. #AD Always read the label. Follow the directions for use. @melrosefuturelab @chemistwarehouse Subscribe to Ageless by Radiance Club so you never miss the latest episode: https://bit.ly/3nQr4UU #agelessradianceclub #ceo Chapters: 00:00 – The Importance of Health Span vs Longevity 03:05 – Understanding the Hallmarks of Ageing 05:58 – Cellular Mechanisms of Ageing and Longevity 09:12 – The Role of Supplements in Ageing Well 11:59 – Berberine: A Key Player in Longevity 15:02 – Navigating the World of Supplements 18:02 – The Future of Health and Wellness 26:32 – Musculoskeletal Health and Ageing 34:00 – Innovations in Formulation and Bioavailability 38:01 – Addressing Menopause and Perimeno https://www.youtube-nocookie.com/embed/i65uno_HZQo 2700 2025-06-02T03:07:11.000Z 2026-10-22T19:32:33.399Z https://longevityharbor.com/de/watch/i65uno_HZQo The Science of Longevity: Neal Mercado on Ageing Better, Not Just Longer https://i.ytimg.com/vi/i65uno_HZQo/hqdefault.jpg If you have come across the longevity bible by Professor David Sinclair, Lifespan, Why we age and Why we don’t have to, you will know that the real goal is expanding our health and vitality for longer. I talk about this a lot on the show as do many of my guests and experts. I’m joined today by Neal Mercado, the Chief Science Officer at Melrose, one of Australia’s leading wellness brands. Neal brings extensive expertise in product formulation and clinical research and most recently advised on the creation of FUTURELAB, a range dedicated to the science of ageing well. With a background in pharmaceutical sciences and over 15 years of experience in developing innovative wellness products, Neal will answer the many questions on the hallmarks of ageing. In this conversation he also shares the meticulous research and insights of the breakthroughs in cellular wellness that will shape the future of ageing. Here’s the good news, the future of ageing looks bright for those looking to extend not just their lifespan, but their health span and longevity- ensuring we live our best, healthiest years for as long as possible. In this conversation with Neal, I explore the latest ingredients, technology and future of ageing better than at any other time in history. This episode is in partnership with Melrose Futurelab, our season sponsor. #AD Always read the label. Follow the directions for use. @melrosefuturelab @chemistwarehouse Subscribe to Ageless by Radiance Club so you never miss the latest episode: https://bit.ly/3nQr4UU #agelessradianceclub #ceo Chapters: 00:00 – The Importance of Health Span vs Longevity 03:05 – Understanding the Hallmarks of Ageing 05:58 – Cellular Mechanisms of Ageing and Longevity 09:12 – The Role of Supplements in Ageing Well 11:59 – Berberine: A Key Player in Longevity 15:02 – Navigating the World of Supplements 18:02 – The Future of Health and Wellness 26:32 – Musculoskeletal Health and Ageing 34:00 – Innovations in Formulation and Bioavailability 38:01 – Addressing Menopause and Perimeno https://www.youtube-nocookie.com/embed/i65uno_HZQo 2700 2025-06-02T03:07:11.000Z 2026-10-22T19:32:33.399Z https://longevityharbor.com/en/watch/i6EAvFvBg64 Podcast description: long-term eating habits versus short-term diets https://i.ytimg.com/vi/i6EAvFvBg64/hqdefault.jpg The description says this podcast episode discusses why long-term eating habits matter more than short-term diets and what protein, healthy fats, fibre and enough fluid contribute to health. https://www.youtube-nocookie.com/embed/i6EAvFvBg64 137 2026-08-05T16:28:33.000Z 2026-10-22T23:13:51.178Z https://longevityharbor.com/de/watch/i6EAvFvBg64 Podcast-Beschreibung: langfristige Essgewohnheiten statt kurzfristiger Diäten https://i.ytimg.com/vi/i6EAvFvBg64/hqdefault.jpg Laut Beschreibung behandelt diese Podcast-Folge, warum langfristige Essgewohnheiten wichtiger sind als kurzfristige Diäten und welche Rolle Eiweiß, gesunde Fette, Ballaststoffe und ausreichend Flüssigkeit für die Gesundheit spielen. https://www.youtube-nocookie.com/embed/i6EAvFvBg64 137 2026-08-05T16:28:33.000Z 2026-10-22T23:13:51.178Z https://longevityharbor.com/en/watch/i6MqeoYxU40 Stanford geriatrician's video description on bone health, posture, power and healthy longevity https://i.ytimg.com/vi/i6MqeoYxU40/hqdefault.jpg In the description, Stanford geriatrician Deborah Kado says the goal should be living well for longer by protecting strength, mobility and independence, and the episode is said to cover hip fracture risk, bone density, posture, strength versus power and NAD supplements. https://www.youtube-nocookie.com/embed/i6MqeoYxU40 4011 2026-04-29T16:01:28.000Z 2026-10-23T01:20:14.548Z https://longevityharbor.com/de/watch/i6MqeoYxU40 Stanford-Geriatrikerin im Videobeschreibungstext zu Knochengesundheit, Haltung, Kraft und gesundem A https://i.ytimg.com/vi/i6MqeoYxU40/hqdefault.jpg Im Beschreibungstext sagt die Stanford-Geriatrikerin Deborah Kado, Ziel sollte es sein, länger gut zu leben, indem Kraft, Mobilität und Selbstständigkeit geschützt werden; die Folge soll Hüftfrakturrisiko, Knochendichte, Haltung, Kraft versus Leistung und NAD-Präparate behandeln. https://www.youtube-nocookie.com/embed/i6MqeoYxU40 4011 2026-04-29T16:01:28.000Z 2026-10-23T01:20:14.548Z https://longevityharbor.com/en/watch/i99EBkZtkVY Six Daily Habits for Healthy Aging After 55: A Video Description Overview https://i.ytimg.com/vi/i99EBkZtkVY/hqdefault.jpg The description presents six daily habits for adults over 55 — movement, strength training, anti-inflammatory nutrition, brain health, social connection and sleep — and says these may support strength, mobility, independence and quality of life. It cites CDC, National Institute on Aging and other resources and includes a medical disclaimer. https://www.youtube-nocookie.com/embed/i99EBkZtkVY 1415 2026-10-08T01:00:09.000Z 2026-10-22T21:00:53.176Z https://longevityharbor.com/de/watch/i99EBkZtkVY Sechs Alltagsgewohnheiten für gesundes Altern ab 55: Überblick über eine Videobeschreibung https://i.ytimg.com/vi/i99EBkZtkVY/hqdefault.jpg Die Beschreibung nennt sechs Alltagsgewohnheiten für Erwachsene über 55 – Bewegung, Krafttraining, entzündungshemmende Ernährung, Gehirngesundheit, soziale Verbundenheit und Schlaf – und sagt, diese könnten Kraft, Mobilität, Selbstständigkeit und Lebensqualität unterstützen. Sie verweist auf CDC, National Institute on Aging und weitere Quellen und enthält einen medizinischen Hinweis. https://www.youtube-nocookie.com/embed/i99EBkZtkVY 1415 2026-10-08T01:00:09.000Z 2026-10-22T21:00:53.176Z https://longevityharbor.com/en/watch/iByoTdXwPwk Video description: intermittent fasting and alternate-day fasting discussed by Krista Varady https://i.ytimg.com/vi/iByoTdXwPwk/hqdefault.jpg The description presents an episode for health practitioners featuring researcher Krista Varady, PhD, on intermittent fasting and alternate-day fasting and their described metabolic effects. It names chronic illness management, healthy aging and disease prevention as topics, but reports no results, numbers or study details. https://www.youtube-nocookie.com/embed/iByoTdXwPwk 1049 2026-01-05T13:01:22.000Z 2026-10-23T03:02:04.546Z https://longevityharbor.com/de/watch/iByoTdXwPwk Videobeschreibung: Intervallfasten und Fasten an alternierenden Tagen mit Krista Varady https://i.ytimg.com/vi/iByoTdXwPwk/hqdefault.jpg Die Beschreibung stellt eine Episode für Gesundheitsfachkräfte mit der Forscherin Krista Varady, PhD, über Intervallfasten und Fasten an alternierenden Tagen sowie beschriebene Stoffwechseleffekte vor. Sie nennt Management chronischer Erkrankungen, gesundes Altern und Krankheitsvorbeugung als Themen, berichtet aber keine Ergebnisse, Zahlen oder Studiendetails. https://www.youtube-nocookie.com/embed/iByoTdXwPwk 1049 2026-01-05T13:01:22.000Z 2026-10-23T03:02:04.546Z https://longevityharbor.com/en/watch/iJJNM-_hcP0 Neue Erkenntnisse zu Fasten und Autophagie 2024 https://i.ytimg.com/vi/iJJNM-_hcP0/hqdefault.jpg Entdecken Sie in dieser Episode von Vital Aging Lab, wie Fasten die Autophagie beim Menschen beeinflusst. Erfahren Sie mehr über die neuesten Forschungsergebnisse und wie Sie diese Erkenntnisse für Ihre Gesundheit nutzen können. GLIEDERUNG: 00:00:00 Einführung in Fasten und Autophagie 00:01:27 Autophagie und ihre Aktivierung 00:02:37 Weitere Maßnahmen zur Stimulierung der Autophagie 00:03:35 Prävention durch Fasten messbar? 00:06:00 Aktuelle Forschung und Entwicklungen 00:06:35 Fazit Quellen: https://typeset.io/papers/the-break-fast-study-protocol-a-single-arm-pre-post-study-to-35noydex https://typeset.io/papers/the-break-fast-study-protocol-a-single-arm-pre-post-study-to-2cjchqs2 https://typeset.io/papers/muscle-fibre-type-specific-autophagy-responses-following-an-2fwfh4we https://typeset.io/papers/mechanisms-of-autophagic-responses-to-altered-nutritional-1jg79rva https://typeset.io/papers/metabolic-effects-of-fasting-on-human-and-mouse-blood-in-35zc84nb69 https://typeset.io/papers/metabolic-effects-of-fasting-on-human-and-mouse-blood-in-35zc84nb69 https://typeset.io/papers/autophagy-response-to-the-use-of-a-comprehensive-health-2lfbtbbz https://typeset.io/papers/effects-of-physiologic-inputs-on-autophagy-2hid4owu https://typeset.io/papers/effects-of-physiologic-inputs-on-autophagy-x84uwi7kus https://www.mdpi.com/2073-4409/8/11/1436 @vitalaginglab Abonniere auf: https://www.youtube.com/@vitalaginglab ________________________________________________________________________ Homepage: https://morciap.de/ Eigene Bücher: E-Book (Kindle Ausgabe): 1) Die Langlebigkeitsrevolution: Länger und gesünder leben https://www.amazon.de/dp/B0C5MMGG8F 2) Von Stress zu Stärke: Die Kraft der Hormesis für Gesundheit und Altern https://www.amazon.de/dp/B0CFLRG2TX 3) SELBST-WERDEN: Bewusstsein hacken, Verhalten ändern https://www.amazon.de/dp/B0CZ4DF473 Taschenbuch: 1) Die Langlebigkeitsrevolution: Länger und gesünder leben https://www.amazon.de/dp/B0C87VXZDQ 2) Von Stress zu Stärke: Di https://www.youtube-nocookie.com/embed/iJJNM-_hcP0 458 2024-02-26T15:00:10.000Z 2026-10-22T17:43:37.678Z https://longevityharbor.com/de/watch/iJJNM-_hcP0 Neue Erkenntnisse zu Fasten und Autophagie 2024 https://i.ytimg.com/vi/iJJNM-_hcP0/hqdefault.jpg Entdecken Sie in dieser Episode von Vital Aging Lab, wie Fasten die Autophagie beim Menschen beeinflusst. Erfahren Sie mehr über die neuesten Forschungsergebnisse und wie Sie diese Erkenntnisse für Ihre Gesundheit nutzen können. GLIEDERUNG: 00:00:00 Einführung in Fasten und Autophagie 00:01:27 Autophagie und ihre Aktivierung 00:02:37 Weitere Maßnahmen zur Stimulierung der Autophagie 00:03:35 Prävention durch Fasten messbar? 00:06:00 Aktuelle Forschung und Entwicklungen 00:06:35 Fazit Quellen: https://typeset.io/papers/the-break-fast-study-protocol-a-single-arm-pre-post-study-to-35noydex https://typeset.io/papers/the-break-fast-study-protocol-a-single-arm-pre-post-study-to-2cjchqs2 https://typeset.io/papers/muscle-fibre-type-specific-autophagy-responses-following-an-2fwfh4we https://typeset.io/papers/mechanisms-of-autophagic-responses-to-altered-nutritional-1jg79rva https://typeset.io/papers/metabolic-effects-of-fasting-on-human-and-mouse-blood-in-35zc84nb69 https://typeset.io/papers/metabolic-effects-of-fasting-on-human-and-mouse-blood-in-35zc84nb69 https://typeset.io/papers/autophagy-response-to-the-use-of-a-comprehensive-health-2lfbtbbz https://typeset.io/papers/effects-of-physiologic-inputs-on-autophagy-2hid4owu https://typeset.io/papers/effects-of-physiologic-inputs-on-autophagy-x84uwi7kus https://www.mdpi.com/2073-4409/8/11/1436 @vitalaginglab Abonniere auf: https://www.youtube.com/@vitalaginglab ________________________________________________________________________ Homepage: https://morciap.de/ Eigene Bücher: E-Book (Kindle Ausgabe): 1) Die Langlebigkeitsrevolution: Länger und gesünder leben https://www.amazon.de/dp/B0C5MMGG8F 2) Von Stress zu Stärke: Die Kraft der Hormesis für Gesundheit und Altern https://www.amazon.de/dp/B0CFLRG2TX 3) SELBST-WERDEN: Bewusstsein hacken, Verhalten ändern https://www.amazon.de/dp/B0CZ4DF473 Taschenbuch: 1) Die Langlebigkeitsrevolution: Länger und gesünder leben https://www.amazon.de/dp/B0C87VXZDQ 2) Von Stress zu Stärke: Di https://www.youtube-nocookie.com/embed/iJJNM-_hcP0 458 2024-02-26T15:00:10.000Z 2026-10-22T17:43:37.678Z https://longevityharbor.com/en/watch/iJlI69LEX_Y Altern nach 70 umkehren: Warum Muskeln Ihr biologisches Alter bestimmen https://i.ytimg.com/vi/iJlI69LEX_Y/hqdefault.jpg Altern nach 70 umkehren: Warum Muskeln Ihr biologisches Alter bestimmen – und was Sie ab morgen tun können. Nach 70 verlieren viele unbemerkt Muskeln – und damit Kraft, Balance und Selbstständigkeit. Dieses Video zeigt, warum Muskeln als Organ für gesund altern und gesundheit ab 60 entscheidend sind und wie sarkopenie wirklich entsteht. In diesem Video erfahren Sie: - warum Muskelverlust ab 70 kein reines Altersschicksal ist, sondern ein biologisches Signal - was anabole Resistenz bedeutet und warum 3 Mahlzeiten mit ernährung ab 60 Fokus besser wirken als ein großes Abendessen - welche 2-3 Kraft-Einheiten pro Woche für große Muskelgruppen in Studien die besten Ergebnisse für Kraft und Alltag zeigten - wie Myokine aus dem Muskel Entzündungen dämpfen und Gehirn und Stoffwechsel unterstützen - wie Mitochondrien, Schlaf und Darm senioren gesundheit Perspektive den Muskelaufbau bremsen oder beschleunigen - einen einfachen 7-Tage-Plan: Gehen mit Intervallen, Kraft, Protein, Schlaf und Balance Ideal für alle ab 60, die gesund altern wollen, Stürze vermeiden und lange selbstständig bleiben möchten. 🔔 Abonnieren Sie Tief Erklärt für wöchentliche Videos zu Psychologie, Gesundheit und Neurowissenschaft – verständlich und wissenschaftlich fundiert. ⚠️ Hinweis: Nur zu Bildungszwecken, kein Ersatz für ärztliche Beratung. Sprechen Sie bei Vorerkrankungen mit Ihrer Ärztin oder Ihrem Arzt. #GesundAb60 #GesundAltern #SeniorenGesundheit https://www.youtube-nocookie.com/embed/iJlI69LEX_Y 656 2026-10-21T08:00:07.000Z 2026-10-22T17:43:36.057Z https://longevityharbor.com/de/watch/iJlI69LEX_Y Altern nach 70 umkehren: Warum Muskeln Ihr biologisches Alter bestimmen https://i.ytimg.com/vi/iJlI69LEX_Y/hqdefault.jpg Altern nach 70 umkehren: Warum Muskeln Ihr biologisches Alter bestimmen – und was Sie ab morgen tun können. Nach 70 verlieren viele unbemerkt Muskeln – und damit Kraft, Balance und Selbstständigkeit. Dieses Video zeigt, warum Muskeln als Organ für gesund altern und gesundheit ab 60 entscheidend sind und wie sarkopenie wirklich entsteht. In diesem Video erfahren Sie: - warum Muskelverlust ab 70 kein reines Altersschicksal ist, sondern ein biologisches Signal - was anabole Resistenz bedeutet und warum 3 Mahlzeiten mit ernährung ab 60 Fokus besser wirken als ein großes Abendessen - welche 2-3 Kraft-Einheiten pro Woche für große Muskelgruppen in Studien die besten Ergebnisse für Kraft und Alltag zeigten - wie Myokine aus dem Muskel Entzündungen dämpfen und Gehirn und Stoffwechsel unterstützen - wie Mitochondrien, Schlaf und Darm senioren gesundheit Perspektive den Muskelaufbau bremsen oder beschleunigen - einen einfachen 7-Tage-Plan: Gehen mit Intervallen, Kraft, Protein, Schlaf und Balance Ideal für alle ab 60, die gesund altern wollen, Stürze vermeiden und lange selbstständig bleiben möchten. 🔔 Abonnieren Sie Tief Erklärt für wöchentliche Videos zu Psychologie, Gesundheit und Neurowissenschaft – verständlich und wissenschaftlich fundiert. ⚠️ Hinweis: Nur zu Bildungszwecken, kein Ersatz für ärztliche Beratung. Sprechen Sie bei Vorerkrankungen mit Ihrer Ärztin oder Ihrem Arzt. #GesundAb60 #GesundAltern #SeniorenGesundheit https://www.youtube-nocookie.com/embed/iJlI69LEX_Y 656 2026-10-21T08:00:07.000Z 2026-10-22T17:43:36.057Z https://longevityharbor.com/en/watch/iLPF9wTdFF4 Video description: nutrition after menopause and a book pre-order https://i.ytimg.com/vi/iLPF9wTdFF4/hqdefault.jpg The description says women's risk of chronic disease rises markedly after menopause and that nutrition is where her book, aimed at postmenopausal women, starts; it offers no study data. https://www.youtube-nocookie.com/embed/iLPF9wTdFF4 92 2026-01-10T10:03:18.000Z 2026-10-23T02:56:51.354Z https://longevityharbor.com/de/watch/iLPF9wTdFF4 Videobeschreibung: Ernährung nach den Wechseljahren und Buch-Vorbestellung https://i.ytimg.com/vi/iLPF9wTdFF4/hqdefault.jpg Die Beschreibung sagt, das Risiko für chronische Erkrankungen steige bei Frauen nach den Wechseljahren deutlich, und dort setze die Ernährung an; ihr Buch richte sich an Frauen in der Postmenopause. Studiendaten nennt sie nicht. https://www.youtube-nocookie.com/embed/iLPF9wTdFF4 92 2026-01-10T10:03:18.000Z 2026-10-23T02:56:51.354Z https://longevityharbor.com/en/watch/iMvf626e1yw Reverse Aging? AI & Longevity Breakthroughs https://i.ytimg.com/vi/iMvf626e1yw/hqdefault.jpg Can we reverse aging? Explore breakthroughs in cognitive reversal, epigenetics, and AI that target the aging process. Learn about FTL1, DunedinPACE, & more! Watch now! #longevity #aging #healthspan #epigenetics #AI #geroscience #cognitivehealth #biotech #reversingaging Chapters: 00:00:00 - Intro 00:00:53 - Reversing Cognitive Decline with FTL1 00:03:31 - Epigenetic Clocks: Measuring Biological Aging 00:05:32 - Heat Waves and Accelerated Aging 00:07:47 - AI Revolutionizing Drug Discovery 00:10:26 - Therapeutic Plasma Exchange: A Promising Intervention 00:11:55 - Ethical Considerations and Safety 00:13:00 - Future Trends in Longevity Science 00:14:27 - Conclusion: Proactive Health-span Management https://www.youtube-nocookie.com/embed/iMvf626e1yw 907 2025-08-27T17:00:59.000Z 2026-10-22T19:54:20.280Z https://longevityharbor.com/de/watch/iMvf626e1yw Reverse Aging? AI & Longevity Breakthroughs https://i.ytimg.com/vi/iMvf626e1yw/hqdefault.jpg Can we reverse aging? Explore breakthroughs in cognitive reversal, epigenetics, and AI that target the aging process. Learn about FTL1, DunedinPACE, & more! Watch now! #longevity #aging #healthspan #epigenetics #AI #geroscience #cognitivehealth #biotech #reversingaging Chapters: 00:00:00 - Intro 00:00:53 - Reversing Cognitive Decline with FTL1 00:03:31 - Epigenetic Clocks: Measuring Biological Aging 00:05:32 - Heat Waves and Accelerated Aging 00:07:47 - AI Revolutionizing Drug Discovery 00:10:26 - Therapeutic Plasma Exchange: A Promising Intervention 00:11:55 - Ethical Considerations and Safety 00:13:00 - Future Trends in Longevity Science 00:14:27 - Conclusion: Proactive Health-span Management https://www.youtube-nocookie.com/embed/iMvf626e1yw 907 2025-08-27T17:00:59.000Z 2026-10-22T19:54:20.280Z https://longevityharbor.com/en/watch/iNakS38F7J0 I’m Taking NMN - What’s the Hype with this “Longevity” Supplement? https://i.ytimg.com/vi/iNakS38F7J0/hqdefault.jpg My Own Experience with NMN ONLY! 15% off Verso NMN with code THOMAS: https://ver.so/ This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Please check out the new workout channel, Garage Built Life, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://pubmed.ncbi.nlm.nih.gov/20668205/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992043/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525320/ https://www.nature.com/articles/nrm.2017.53 https://www.sciencedirect.com/science/article/pii/S2468501118300063#bib23 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222897/ https://www.e-agmr.org/upload/pdf/AGMR021-04-02.pdf https://pubmed.ncbi.nlm.nih.gov/19286518/ https://www.nature.com/articles/s41580-020-0254-8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101526/ https://www.jneurosci.org/content/40/3/694 https://www.sciencedirect.com/science/article/pii/S1568163717300065 https://www.nature.com/articles/s42255-018-0009-4 https://pubmed.ncbi.nlm.nih.gov/26574954/ https://www.nature.com/articles/ncomms13103 https://www.sciencedirect.com/science/article/pii/S1550413116304958 https://pubmed.ncbi.nlm.nih.gov/23185430/ https://www.hindawi.com/journals/omcl/2017/4602715/ https://www.youtube-nocookie.com/embed/iNakS38F7J0 707 2021-04-21T14:57:46.000Z 2026-10-23T00:51:10.485Z https://longevityharbor.com/de/watch/iNakS38F7J0 I’m Taking NMN - What’s the Hype with this “Longevity” Supplement? https://i.ytimg.com/vi/iNakS38F7J0/hqdefault.jpg My Own Experience with NMN ONLY! 15% off Verso NMN with code THOMAS: https://ver.so/ This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Please check out the new workout channel, Garage Built Life, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://pubmed.ncbi.nlm.nih.gov/20668205/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992043/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525320/ https://www.nature.com/articles/nrm.2017.53 https://www.sciencedirect.com/science/article/pii/S2468501118300063#bib23 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222897/ https://www.e-agmr.org/upload/pdf/AGMR021-04-02.pdf https://pubmed.ncbi.nlm.nih.gov/19286518/ https://www.nature.com/articles/s41580-020-0254-8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101526/ https://www.jneurosci.org/content/40/3/694 https://www.sciencedirect.com/science/article/pii/S1568163717300065 https://www.nature.com/articles/s42255-018-0009-4 https://pubmed.ncbi.nlm.nih.gov/26574954/ https://www.nature.com/articles/ncomms13103 https://www.sciencedirect.com/science/article/pii/S1550413116304958 https://pubmed.ncbi.nlm.nih.gov/23185430/ https://www.hindawi.com/journals/omcl/2017/4602715/ https://www.youtube-nocookie.com/embed/iNakS38F7J0 707 2021-04-21T14:57:46.000Z 2026-10-23T00:51:10.485Z https://longevityharbor.com/en/watch/iNvx-XYeCtU Longevity MealPrep Tipp Quittenmus #quitte #healthyeating #healthyaging https://i.ytimg.com/vi/iNvx-XYeCtU/hqdefault.jpg Epigenetik und gesund Altern ist die Welt von Longevity - die Gesundheit im Alter zu verlängern! Mit dem 90 Tage Epigenetik Transformation Begleitprogramm zeige ich in einer 360 Grad Betrachtung, welche Bereiche deiner Umwelt du beeinflussen kannst, um deine Gesundheit ganzheitlich zu verbessern. Buche dir ein 30 min Klarheitsgespräch kostenfrei mit Lydia: https://calendly.com/lydiafillbach/erstgespraech_epigenetik_transformation_30min Gerne kannst du meine Angebote hier kennen lernen: Epigenetik 90 Tage Transformation 1:1 Begleitprogramm mit Lydia https://www.lebenswert-wien.at/traumkoerper/ Gesundheitszentrum in Wien & Webshop: https://www.lebenswert-wien.at/ Human Design Mentoring 1:1 mit Lydia: https://www.lebenswert-wien.at/human-design-analyse/ Ich bin mir sicher, dass du bei mir nicht nur KLARHEIT findest, sondern auch den nächsten wichtigen IMPULS auf dem Weg zu deinem entspannt erfülltem Leben als strahlend selbstbewusstes Menschenkind :-) Deine Lydia Fillbach https://www.youtube-nocookie.com/embed/iNvx-XYeCtU 117 2025-10-21T16:42:06.000Z 2026-10-22T18:54:03.319Z https://longevityharbor.com/de/watch/iNvx-XYeCtU Longevity MealPrep Tipp Quittenmus #quitte #healthyeating #healthyaging https://i.ytimg.com/vi/iNvx-XYeCtU/hqdefault.jpg Epigenetik und gesund Altern ist die Welt von Longevity - die Gesundheit im Alter zu verlängern! Mit dem 90 Tage Epigenetik Transformation Begleitprogramm zeige ich in einer 360 Grad Betrachtung, welche Bereiche deiner Umwelt du beeinflussen kannst, um deine Gesundheit ganzheitlich zu verbessern. Buche dir ein 30 min Klarheitsgespräch kostenfrei mit Lydia: https://calendly.com/lydiafillbach/erstgespraech_epigenetik_transformation_30min Gerne kannst du meine Angebote hier kennen lernen: Epigenetik 90 Tage Transformation 1:1 Begleitprogramm mit Lydia https://www.lebenswert-wien.at/traumkoerper/ Gesundheitszentrum in Wien & Webshop: https://www.lebenswert-wien.at/ Human Design Mentoring 1:1 mit Lydia: https://www.lebenswert-wien.at/human-design-analyse/ Ich bin mir sicher, dass du bei mir nicht nur KLARHEIT findest, sondern auch den nächsten wichtigen IMPULS auf dem Weg zu deinem entspannt erfülltem Leben als strahlend selbstbewusstes Menschenkind :-) Deine Lydia Fillbach https://www.youtube-nocookie.com/embed/iNvx-XYeCtU 117 2025-10-21T16:42:06.000Z 2026-10-22T18:54:03.319Z https://longevityharbor.com/en/watch/iQFGBCBmlQ8 Video description: five intermittent fasting claims checked against cited research https://i.ytimg.com/vi/iQFGBCBmlQ8/hqdefault.jpg The description says five common intermittent fasting claims were checked against the actual studies, separating published human research from mouse findings presented as human health claims. https://www.youtube-nocookie.com/embed/iQFGBCBmlQ8 542 2026-09-11T18:00:28.000Z 2026-10-22T22:21:12.163Z https://longevityharbor.com/de/watch/iQFGBCBmlQ8 Videobeschreibung: fünf Intervallfasten-Behauptungen an zitierter Forschung geprüft https://i.ytimg.com/vi/iQFGBCBmlQ8/hqdefault.jpg Laut Beschreibung wurden fünf verbreitete Intervallfasten-Behauptungen an den eigentlichen Studien geprüft und veröffentlichte Humanforschung von Mausbefunden getrennt, die als Gesundheitsaussagen für Menschen dargestellt werden. https://www.youtube-nocookie.com/embed/iQFGBCBmlQ8 542 2026-09-11T18:00:28.000Z 2026-10-22T22:21:12.163Z https://longevityharbor.com/en/watch/iUSC83DV3w8 Family longevity, glucose regulation and mTOR genes described in a short video https://i.ytimg.com/vi/iUSC83DV3w8/hqdefault.jpg The description asks whether longevity runs in families and says the video explores genetic and biological factors of a long life, from glucose regulation to specific gene expressions, with a focus on the mTOR pathway. It reports no results. https://www.youtube-nocookie.com/embed/iUSC83DV3w8 139 2026-01-16T16:58:42.000Z 2026-10-23T02:49:27.006Z https://longevityharbor.com/de/watch/iUSC83DV3w8 Familiäre Langlebigkeit, Glukoseregulation und mTOR-Gene in einem Kurzvideo beschrieben https://i.ytimg.com/vi/iUSC83DV3w8/hqdefault.jpg Die Beschreibung fragt, ob Langlebigkeit in Familien liegt, und nennt genetische und biologische Faktoren eines langen Lebens als Thema, von Glukoseregulation bis zu bestimmten Genexpressionen, mit Schwerpunkt auf dem mTOR-Signalweg. Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/iUSC83DV3w8 139 2026-01-16T16:58:42.000Z 2026-10-23T02:49:27.006Z https://longevityharbor.com/en/watch/ibfW9y200S0 Rapamycin: The Longevity Drug — Matt Kaeberlein Explains https://i.ytimg.com/vi/ibfW9y200S0/hqdefault.jpg Rapamycin is the most promising longevity drug ever discovered — found in Easter Island soil, it extends lifespan in every species tested. Aging researcher Matt Kaeberlein explains why it works and whether you should take it. In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Dr. Matt Kaeberlein, former professor at the University of Washington School of Medicine and co-founder of Ora Biomedical, to explore rapamycin's mechanism of action, the mTOR pathway, real-world dosing protocols, the Dog Aging Project, and why this compound may be the closest thing we have to an anti-aging pill. CHAPTERS: 00:00 — Introduction 04:06 — Dr. Matt Kaeberlein's Path to Aging Research 06:07 — What Is Biological Aging vs. Chronological Aging? 08:08 — Foundational Mechanisms of Aging: What We Know 10:09 — Lifestyle Interventions: Diet, Exercise, and Caloric Restriction 12:10 — What Is Rapamycin and Where Did It Come From? 14:10 — How mTOR Controls Growth, Reproduction, and Aging 17:10 — How Rapamycin Extends Lifespan in Every Species Tested 19:11 — Does Rapamycin Mimic Caloric Restriction? 21:12 — Rapamycin Reverses Age-Related Immune Decline 23:13 — Why Wasn't Rapamycin Discovered as a Longevity Drug Sooner? 25:14 — The Easter Island Connection: From Antifungal to Longevity 27:15 — mTOR vs. Non-mTOR Effects of Rapamycin 29:16 — Intermittent Fasting and mTOR Inhibition 31:19 — Rapamycin Dosing for Longevity vs. Immunosuppression 33:20 — Side Effects at Low Doses: What the Data Actually Shows 35:21 — Mouth Sores as a Biomarker: Good Sign or Bad Sign? 37:22 — Rapamycin, Autophagy, and Cellular Stress Resistance 39:24 — Hormesis and the Dose-Response Curve of mTOR Inhibition 41:26 — mTOR, Chronic Inflammation, and Age-Related Disease 43:26 — Rapamycin and Brain Health: Alzheimer's and Depression 45:26 — Ketogenic Diet, mTOR, and Mental Health 47:29 — The Dog Aging Project: Rapamycin in Companion Dogs 49:30 — Feeding Frequency and Canine Longevity 51:32 — What We've Learned So Far From Dog Aging Studies 53:36 https://www.youtube-nocookie.com/embed/ibfW9y200S0 3249 2024-06-08T13:22:32.000Z 2026-10-22T19:54:22.327Z https://longevityharbor.com/de/watch/ibfW9y200S0 Rapamycin: The Longevity Drug — Matt Kaeberlein Explains https://i.ytimg.com/vi/ibfW9y200S0/hqdefault.jpg Rapamycin is the most promising longevity drug ever discovered — found in Easter Island soil, it extends lifespan in every species tested. Aging researcher Matt Kaeberlein explains why it works and whether you should take it. In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Dr. Matt Kaeberlein, former professor at the University of Washington School of Medicine and co-founder of Ora Biomedical, to explore rapamycin's mechanism of action, the mTOR pathway, real-world dosing protocols, the Dog Aging Project, and why this compound may be the closest thing we have to an anti-aging pill. CHAPTERS: 00:00 — Introduction 04:06 — Dr. Matt Kaeberlein's Path to Aging Research 06:07 — What Is Biological Aging vs. Chronological Aging? 08:08 — Foundational Mechanisms of Aging: What We Know 10:09 — Lifestyle Interventions: Diet, Exercise, and Caloric Restriction 12:10 — What Is Rapamycin and Where Did It Come From? 14:10 — How mTOR Controls Growth, Reproduction, and Aging 17:10 — How Rapamycin Extends Lifespan in Every Species Tested 19:11 — Does Rapamycin Mimic Caloric Restriction? 21:12 — Rapamycin Reverses Age-Related Immune Decline 23:13 — Why Wasn't Rapamycin Discovered as a Longevity Drug Sooner? 25:14 — The Easter Island Connection: From Antifungal to Longevity 27:15 — mTOR vs. Non-mTOR Effects of Rapamycin 29:16 — Intermittent Fasting and mTOR Inhibition 31:19 — Rapamycin Dosing for Longevity vs. Immunosuppression 33:20 — Side Effects at Low Doses: What the Data Actually Shows 35:21 — Mouth Sores as a Biomarker: Good Sign or Bad Sign? 37:22 — Rapamycin, Autophagy, and Cellular Stress Resistance 39:24 — Hormesis and the Dose-Response Curve of mTOR Inhibition 41:26 — mTOR, Chronic Inflammation, and Age-Related Disease 43:26 — Rapamycin and Brain Health: Alzheimer's and Depression 45:26 — Ketogenic Diet, mTOR, and Mental Health 47:29 — The Dog Aging Project: Rapamycin in Companion Dogs 49:30 — Feeding Frequency and Canine Longevity 51:32 — What We've Learned So Far From Dog Aging Studies 53:36 https://www.youtube-nocookie.com/embed/ibfW9y200S0 3249 2024-06-08T13:22:32.000Z 2026-10-22T19:54:22.327Z https://longevityharbor.com/en/watch/idbSM-c6_I0 How Old Are You? The Rise of Epigenetic Clocks https://i.ytimg.com/vi/idbSM-c6_I0/hqdefault.jpg Forget what you think you know about aging. Your birthdate is just a number, but your biological age tells the real story. We're about to expose the groundbreaking science of epigenetic clocks, the technology that's quantifying your body's true wear and tear. Prepare to have your mind blown as we explore how this scientific breakthrough is redefining our understanding of longevity and human health. This video is based on original content from the EON.HEALTH newsletter, which you can also find on our blog: 👉 eon.health/blog https://www.youtube-nocookie.com/embed/idbSM-c6_I0 346 2025-08-01T18:34:25.000Z 2026-10-22T19:21:27.521Z https://longevityharbor.com/de/watch/idbSM-c6_I0 How Old Are You? The Rise of Epigenetic Clocks https://i.ytimg.com/vi/idbSM-c6_I0/hqdefault.jpg Forget what you think you know about aging. Your birthdate is just a number, but your biological age tells the real story. We're about to expose the groundbreaking science of epigenetic clocks, the technology that's quantifying your body's true wear and tear. Prepare to have your mind blown as we explore how this scientific breakthrough is redefining our understanding of longevity and human health. This video is based on original content from the EON.HEALTH newsletter, which you can also find on our blog: 👉 eon.health/blog https://www.youtube-nocookie.com/embed/idbSM-c6_I0 346 2025-08-01T18:34:25.000Z 2026-10-22T19:21:27.521Z https://longevityharbor.com/en/watch/if4Ck-7z6Uo Der Fitnessprofessor: Die besten Tipps für starke Muskeln in jedem Alter | Prof. Stephan Geisler #31 https://i.ytimg.com/vi/if4Ck-7z6Uo/hqdefault.jpg In dieser Episode spreche ich mit Prof. Stephan Geisler, Professor für Gesundheit und Fitness an der IST-Hochschule in Düsseldorf. Prof. Geisler ist außerdem Präsident der National Strength and Conditioning Association Deutschland und Gründer des Fitnesswissenschaftenkongresses. Eine starke und gesunde Muskulatur ist eine der wichtigsten Grundlagen für ein langes und gesundes Leben. Doch welche Strategien sind wirklich effektiv, um in jeder Lebensphase Muskulatur aufzubauen und zu erhalten? Genau darum geht es in dieser Episode! Zusätzlich erfährst du: Wie beeinflusst Krafttraining den Stoffwechsel und das Gehirn? Welche Trainingsmethoden sind wirklich effektiv, und wie sollte man trainieren, um langfristig gesund und fit zu bleiben? Kann man im jeden Alter noch Muskeln & Kraft aufbauen? Wie beeinflussen Kälte & Sauna den Muskelaufbau? Modern Medicine lebt von der Unterstützung der Menschen, die diesen Podcast hören. Wenn du dazu beitragen willst, dass es weitergeht, und zusätzlich exklusive Bonusinhalte erhalten möchtest, kannst du mich hier supporten: ⁠⁠⁠⁠https://steady.page/modern-medicine⁠⁠⁠⁠ Kapitel: 00:01:00 Warum sind Muskeln so wichtig für die Gesundheit? 00:02:00 Blutzuckerkontrolle & Stoffwechselgesundheit 00:04:00 Insulinunabhängige Glukoseaufnahme 00:06:00 Beeinflussung des Gehirns durch Myokine 00:09:00 Sarkopenie 00:10:30 Bewegung & Krafttraining 00:12:00 Grundlegende Trainingsprinzipien 00:13:30 Übungsauswahl 00:14:30 Maschinen vs Freihanteltraining 00:16:30 Sturzprävention im Alter 00:18:00 Optimale Wiederholungsanzahl 00:20:00 Trainingsintensität: Wie nah muss ich ans Muskelversagen? 00:25:30 Wieso Progressive Overload zentral ist 00:29:00 Split-Training 00:32:00 Trainingsfrequenz 00:33:00 Optimale Satzanzahl pro Muskelgruppe 00:35:30 Braucht man Muskelkater für den Muskelaufbau 00:38:00 Übungsvariation 00:40:00 Zwischenzusammenfassung 00:42:30 Proteinzufuhr 00:45:30 Kohlenhydrat & Fettverhältnis 00:49:00 Kalorienüberschuss: “Massephase” 00:50:00 Messung der Muskel- https://www.youtube-nocookie.com/embed/if4Ck-7z6Uo 4483 2025-01-02T16:57:57.000Z 2026-10-22T17:43:36.034Z https://longevityharbor.com/de/watch/if4Ck-7z6Uo Der Fitnessprofessor: Die besten Tipps für starke Muskeln in jedem Alter | Prof. Stephan Geisler #31 https://i.ytimg.com/vi/if4Ck-7z6Uo/hqdefault.jpg In dieser Episode spreche ich mit Prof. Stephan Geisler, Professor für Gesundheit und Fitness an der IST-Hochschule in Düsseldorf. Prof. Geisler ist außerdem Präsident der National Strength and Conditioning Association Deutschland und Gründer des Fitnesswissenschaftenkongresses. Eine starke und gesunde Muskulatur ist eine der wichtigsten Grundlagen für ein langes und gesundes Leben. Doch welche Strategien sind wirklich effektiv, um in jeder Lebensphase Muskulatur aufzubauen und zu erhalten? Genau darum geht es in dieser Episode! Zusätzlich erfährst du: Wie beeinflusst Krafttraining den Stoffwechsel und das Gehirn? Welche Trainingsmethoden sind wirklich effektiv, und wie sollte man trainieren, um langfristig gesund und fit zu bleiben? Kann man im jeden Alter noch Muskeln & Kraft aufbauen? Wie beeinflussen Kälte & Sauna den Muskelaufbau? Modern Medicine lebt von der Unterstützung der Menschen, die diesen Podcast hören. Wenn du dazu beitragen willst, dass es weitergeht, und zusätzlich exklusive Bonusinhalte erhalten möchtest, kannst du mich hier supporten: ⁠⁠⁠⁠https://steady.page/modern-medicine⁠⁠⁠⁠ Kapitel: 00:01:00 Warum sind Muskeln so wichtig für die Gesundheit? 00:02:00 Blutzuckerkontrolle & Stoffwechselgesundheit 00:04:00 Insulinunabhängige Glukoseaufnahme 00:06:00 Beeinflussung des Gehirns durch Myokine 00:09:00 Sarkopenie 00:10:30 Bewegung & Krafttraining 00:12:00 Grundlegende Trainingsprinzipien 00:13:30 Übungsauswahl 00:14:30 Maschinen vs Freihanteltraining 00:16:30 Sturzprävention im Alter 00:18:00 Optimale Wiederholungsanzahl 00:20:00 Trainingsintensität: Wie nah muss ich ans Muskelversagen? 00:25:30 Wieso Progressive Overload zentral ist 00:29:00 Split-Training 00:32:00 Trainingsfrequenz 00:33:00 Optimale Satzanzahl pro Muskelgruppe 00:35:30 Braucht man Muskelkater für den Muskelaufbau 00:38:00 Übungsvariation 00:40:00 Zwischenzusammenfassung 00:42:30 Proteinzufuhr 00:45:30 Kohlenhydrat & Fettverhältnis 00:49:00 Kalorienüberschuss: “Massephase” 00:50:00 Messung der Muskel- https://www.youtube-nocookie.com/embed/if4Ck-7z6Uo 4483 2025-01-02T16:57:57.000Z 2026-10-22T17:43:36.034Z https://longevityharbor.com/en/watch/ijQWt5f9AcY What Aging Really Is—and How to Slow It https://i.ytimg.com/vi/ijQWt5f9AcY/hqdefault.jpg Most people think aging is about getting older. But the truth? It’s about how fast your cells are breaking down—and you can actually slow it down. In this episode of Extend, I sit down with Chris Mirabile, longevity researcher, entrepreneur, and founder of NOVOS, to break down the science of biological aging. We unpack the 12 hallmarks of aging, what they really mean for your health, and how to take control of the root causes—starting today. You’ll learn why you might look and feel older than you are, how things like inflammation, epigenetics, and mitochondrial decline drive disease, and how to measure and improve your true biological age. This isn’t anti-aging fluff. It’s science-backed, future-facing, and practical for anyone serious about living longer and better. We Also Cover: ✅ Why your real age might be older than you think ✅ The truth about inflammation, free radicals & aging skin ✅ What the 12 hallmarks of aging actually are ✅ How epigenetics and mitochondria drive aging at the cellular level ✅ Interventions that actually slow down biological age If you care about longevity, performance, and disease prevention—this episode is a must. 👉 Subscribe for more bold, science-backed episodes to help you extend your healthspan, upgrade your biology, and thrive in today’s toxic world. 📲 Follow Dr. Shah: Website: drshah.com Next Health: next-health.com Instagram: @darshanshahmd YouTube: @DrDarshanShah 📲 Follow Chris Mirabile: Website: novoslabs.com Instagram: @slowmyage Twitter/X: @slowmyage https://www.youtube-nocookie.com/embed/ijQWt5f9AcY 6538 2025-07-31T15:01:15.000Z 2026-10-22T17:43:39.338Z https://longevityharbor.com/de/watch/ijQWt5f9AcY What Aging Really Is—and How to Slow It https://i.ytimg.com/vi/ijQWt5f9AcY/hqdefault.jpg Most people think aging is about getting older. But the truth? It’s about how fast your cells are breaking down—and you can actually slow it down. In this episode of Extend, I sit down with Chris Mirabile, longevity researcher, entrepreneur, and founder of NOVOS, to break down the science of biological aging. We unpack the 12 hallmarks of aging, what they really mean for your health, and how to take control of the root causes—starting today. You’ll learn why you might look and feel older than you are, how things like inflammation, epigenetics, and mitochondrial decline drive disease, and how to measure and improve your true biological age. This isn’t anti-aging fluff. It’s science-backed, future-facing, and practical for anyone serious about living longer and better. We Also Cover: ✅ Why your real age might be older than you think ✅ The truth about inflammation, free radicals & aging skin ✅ What the 12 hallmarks of aging actually are ✅ How epigenetics and mitochondria drive aging at the cellular level ✅ Interventions that actually slow down biological age If you care about longevity, performance, and disease prevention—this episode is a must. 👉 Subscribe for more bold, science-backed episodes to help you extend your healthspan, upgrade your biology, and thrive in today’s toxic world. 📲 Follow Dr. Shah: Website: drshah.com Next Health: next-health.com Instagram: @darshanshahmd YouTube: @DrDarshanShah 📲 Follow Chris Mirabile: Website: novoslabs.com Instagram: @slowmyage Twitter/X: @slowmyage https://www.youtube-nocookie.com/embed/ijQWt5f9AcY 6538 2025-07-31T15:01:15.000Z 2026-10-22T17:43:39.338Z https://longevityharbor.com/en/watch/imDGDOwzL2A Advancing Muscle Health Research: Dr. Stuart Phillips on Nutrition, Aging, and Exercise https://i.ytimg.com/vi/imDGDOwzL2A/hqdefault.jpg Advancing Muscle Health Research: Dr. Stuart Phillips on Nutrition, Aging, and Exercise https://www.youtube-nocookie.com/embed/imDGDOwzL2A 2398 2026-06-11T20:42:12.000Z 2026-10-22T17:43:36.922Z https://longevityharbor.com/de/watch/imDGDOwzL2A Advancing Muscle Health Research: Dr. Stuart Phillips on Nutrition, Aging, and Exercise https://i.ytimg.com/vi/imDGDOwzL2A/hqdefault.jpg Advancing Muscle Health Research: Dr. Stuart Phillips on Nutrition, Aging, and Exercise https://www.youtube-nocookie.com/embed/imDGDOwzL2A 2398 2026-06-11T20:42:12.000Z 2026-10-22T17:43:36.922Z https://longevityharbor.com/en/watch/inqpZpI_qEY Epigenetische Uhren & biologisches Alter mit Prof. Dr. Brigitte König https://i.ytimg.com/vi/inqpZpI_qEY/hqdefault.jpg Epigenetik TV - Im Interview: Prof. Dr. Brigitte König über Epigenetische Uhren & unser biologisches Alter Prof. Dr. Brigitte König ist Expertin für Mikrobiologie und Infektionsimmunologie Sie hat Biologie, Chemie und Medizin studiert, sie hat habilitiert im Fach »Medizinische Mikrobiologie und Infektionsimmunologie« und hat 2008 das Labor MMD gegründet. Heute haben wir eine von Deutschlands größten Forscherinnen im Interview. Ich war ganz besonders gespannt, darauf, was uns Brigitte über Epigenetik, die Methylierung und über viele andere Prozesse berichtet, um auch mal die wissenschaftliche Seite zu durchleuchten. Was wissen wir über die Epigenetik und was ist mehr Vermutung oder Theorie. Sei gespannt, es war ein sehr interessantes und wissensreiches interview. ------------------------ Das Ganze Interview findest du auf https://epi-genes.com/Epigenetik_TV.aspx ------------------------ https://www.youtube-nocookie.com/embed/inqpZpI_qEY 122 2023-04-21T05:00:18.000Z 2026-10-22T17:11:30.650Z https://longevityharbor.com/de/watch/inqpZpI_qEY Epigenetische Uhren & biologisches Alter mit Prof. Dr. Brigitte König https://i.ytimg.com/vi/inqpZpI_qEY/hqdefault.jpg Epigenetik TV - Im Interview: Prof. Dr. Brigitte König über Epigenetische Uhren & unser biologisches Alter Prof. Dr. Brigitte König ist Expertin für Mikrobiologie und Infektionsimmunologie Sie hat Biologie, Chemie und Medizin studiert, sie hat habilitiert im Fach »Medizinische Mikrobiologie und Infektionsimmunologie« und hat 2008 das Labor MMD gegründet. Heute haben wir eine von Deutschlands größten Forscherinnen im Interview. Ich war ganz besonders gespannt, darauf, was uns Brigitte über Epigenetik, die Methylierung und über viele andere Prozesse berichtet, um auch mal die wissenschaftliche Seite zu durchleuchten. Was wissen wir über die Epigenetik und was ist mehr Vermutung oder Theorie. Sei gespannt, es war ein sehr interessantes und wissensreiches interview. ------------------------ Das Ganze Interview findest du auf https://epi-genes.com/Epigenetik_TV.aspx ------------------------ https://www.youtube-nocookie.com/embed/inqpZpI_qEY 122 2023-04-21T05:00:18.000Z 2026-10-22T17:11:30.650Z https://longevityharbor.com/en/watch/ipw1LWtStCw Video description: muscle mass, strength and independence with ageing https://i.ytimg.com/vi/ipw1LWtStCw/hqdefault.jpg The description says an emergency-medicine doctor argues that muscle mass and strength, not cholesterol, weight or genetics, best predict independence and lifespan, and presents strength training as a tool for blood sugar, metabolic health, brain function, falls and independence. https://www.youtube-nocookie.com/embed/ipw1LWtStCw 1157 2025-12-19T15:01:32.000Z 2026-10-23T03:15:06.053Z https://longevityharbor.com/de/watch/ipw1LWtStCw Videobeschreibung: Muskelmasse, Kraft und Selbstständigkeit im Alter https://i.ytimg.com/vi/ipw1LWtStCw/hqdefault.jpg Laut Beschreibung argumentiert ein Notfallmediziner, dass Muskelmasse und Kraft – nicht Cholesterin, Gewicht oder Genetik – Selbstständigkeit und Lebensdauer am besten vorhersagen, und stellt Krafttraining als Werkzeug für Blutzucker, Stoffwechsel, Hirnfunktion, Stürze und Selbstständigkeit dar. https://www.youtube-nocookie.com/embed/ipw1LWtStCw 1157 2025-12-19T15:01:32.000Z 2026-10-23T03:15:06.053Z https://longevityharbor.com/en/watch/ipwJhC-o0e4 Q&A with Scientist Matt Kaeberlein about Longevity and Living Longer | The Optispan Podcast EP 1 https://i.ytimg.com/vi/ipwJhC-o0e4/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Optispan CEO Matt Kaeberlein takes questions about healthy aging. 0:00 Trailer/Introduction 01:23 Why do we get sicker and more frail as we get older? 03:34 Has science figured out how to tackle the Hallmarks of Aging in humans? 06:33 What are the most promising areas of longevity/geroscience research? 11:46 How can we shorten the length of human clinical trials [so drugs can get to market faster]? 16:35 What's the most important thing to ensure a healthy old age? 18:51 Do you have any strong opinions about how nutrition affects healthspan? 23:42 How can a non-expert separate the good science from the snake oil? 29:16 What has surprised you the most about longevity and geroscience research? Producer: Tara Mei Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. The views and opinions expressed in this program are those of the speakers and do not necessarily reflect the policies or positions of Optispan or related entities. Any content is not intended to malign any religion, organization, company, or individual. More places https://www.youtube-nocookie.com/embed/ipwJhC-o0e4 1991 2024-01-12T10:00:28.000Z 2026-10-22T19:54:20.474Z https://longevityharbor.com/de/watch/ipwJhC-o0e4 Q&A with Scientist Matt Kaeberlein about Longevity and Living Longer | The Optispan Podcast EP 1 https://i.ytimg.com/vi/ipwJhC-o0e4/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Optispan CEO Matt Kaeberlein takes questions about healthy aging. 0:00 Trailer/Introduction 01:23 Why do we get sicker and more frail as we get older? 03:34 Has science figured out how to tackle the Hallmarks of Aging in humans? 06:33 What are the most promising areas of longevity/geroscience research? 11:46 How can we shorten the length of human clinical trials [so drugs can get to market faster]? 16:35 What's the most important thing to ensure a healthy old age? 18:51 Do you have any strong opinions about how nutrition affects healthspan? 23:42 How can a non-expert separate the good science from the snake oil? 29:16 What has surprised you the most about longevity and geroscience research? Producer: Tara Mei Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan YouTube channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. The views and opinions expressed in this program are those of the speakers and do not necessarily reflect the policies or positions of Optispan or related entities. Any content is not intended to malign any religion, organization, company, or individual. More places https://www.youtube-nocookie.com/embed/ipwJhC-o0e4 1991 2024-01-12T10:00:28.000Z 2026-10-22T19:54:20.474Z https://longevityharbor.com/en/watch/irnEy0uFVkM Journal Club September 2017 - The Hallmarks of Aging https://i.ytimg.com/vi/irnEy0uFVkM/hqdefault.jpg Dr. Oliver Medvedik hosts the September edition of Journal Club, our monthly livestreamed event where we review and discuss the latest scientific research publications relating to life extension and aging. This month, we look at the Hallmarks of Aging, a groundbreaking paper that divides the processes of aging into distinct hallmarks. ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a "Lifespan Hero": http://lifespan.io/hero ► #LifespanIO #JournalClub #HallmarksOfAging https://www.youtube-nocookie.com/embed/irnEy0uFVkM 6204 2018-05-24T12:35:58.000Z 2026-10-22T17:43:40.147Z https://longevityharbor.com/de/watch/irnEy0uFVkM Journal Club September 2017 - The Hallmarks of Aging https://i.ytimg.com/vi/irnEy0uFVkM/hqdefault.jpg Dr. Oliver Medvedik hosts the September edition of Journal Club, our monthly livestreamed event where we review and discuss the latest scientific research publications relating to life extension and aging. This month, we look at the Hallmarks of Aging, a groundbreaking paper that divides the processes of aging into distinct hallmarks. ►Subscribe for more: http://www.youtube.com/user/LifespanIO?sub_confirmation=1 ►This video is presented by LEAF. Please support our work by becoming a "Lifespan Hero": http://lifespan.io/hero ► #LifespanIO #JournalClub #HallmarksOfAging https://www.youtube-nocookie.com/embed/irnEy0uFVkM 6204 2018-05-24T12:35:58.000Z 2026-10-22T17:43:40.147Z https://longevityharbor.com/en/watch/iuu-SkHhk3E Video description: Harvard diet study and five food swaps for healthy aging https://i.ytimg.com/vi/iuu-SkHhk3E/hqdefault.jpg The description says a Harvard study tracked 120,000 people for 30 years and that the video presents its findings plus five everyday food swaps. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/iuu-SkHhk3E 373 2026-06-18T21:00:20.000Z 2026-10-22T23:57:00.792Z https://longevityharbor.com/de/watch/iuu-SkHhk3E Videobeschreibung: Harvard-Ernährungsstudie und fünf Lebensmitteltausche für gesundes Altern https://i.ytimg.com/vi/iuu-SkHhk3E/hqdefault.jpg Laut Beschreibung verfolgte eine Harvard-Studie 120.000 Menschen über 30 Jahre; das Video stellt die Ergebnisse und fünf alltägliche Lebensmitteltausche vor. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/iuu-SkHhk3E 373 2026-06-18T21:00:20.000Z 2026-10-22T23:57:00.792Z https://longevityharbor.com/en/watch/ivP3QTyQ2d4 Reversing Biological Age: Have we finally found the answer? | 30 - LTW #5 https://i.ytimg.com/vi/ivP3QTyQ2d4/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Matt recently exchanged a lively correspondence about biological age with Harold Katcher, cofounder of a stealth biotechnology company and inventor of E5. E5 is a compound consisting of the purified exosome fraction of blood from young piglets—in other words, young pig blood. Harold recently co-published a paper suggesting that injecting this young pig blood into rats made rats younger on several biological aging measures, including inflammatory markers and epigenetic aging signatures. Indeed, Harold has injected E5 into his own right hand and presented differences in the appearance of his right and left hands on social media. Putting pig blood into other animals (and into ourselves!) to reverse biological age might seem like a crazy thing to do. But this idea actually stems from a methodology with a decades-long history called heterochronic parabiosis, an area of research that explores the effects of joining the circulatory systems of different-aged organisms. In this experimental technique, researchers surgically connect two animals, typically mice, of disparate ages so that they share a common bloodstream. This union leads the older and younger individuals to exchange not just blood cells but also signaling molecules, growth factors, and other circulating factors. Remarkably, when an older animal is paired with a younger counterpart, it often experiences improvements in various aspects of health and tissue function, while the younger partner may exhibit corresponding signs of accelerated aging. The mechanisms underlying these effects are complex, multifaceted, and very much still under investigation. In this episode, Matt takes a magnifying glass to E5: what we know about the compound, how it affects lifespan, and how its impact on lifespan stacks up with that of other longevity inventions such as caloric restriction and rapamycin. He discusses whether Harold's recent paper truly proves a reversal of biological age and where his findings fit into https://www.youtube-nocookie.com/embed/ivP3QTyQ2d4 3017 2024-05-07T14:30:17.000Z 2026-10-22T19:54:20.414Z https://longevityharbor.com/de/watch/ivP3QTyQ2d4 Reversing Biological Age: Have we finally found the answer? | 30 - LTW #5 https://i.ytimg.com/vi/ivP3QTyQ2d4/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Matt recently exchanged a lively correspondence about biological age with Harold Katcher, cofounder of a stealth biotechnology company and inventor of E5. E5 is a compound consisting of the purified exosome fraction of blood from young piglets—in other words, young pig blood. Harold recently co-published a paper suggesting that injecting this young pig blood into rats made rats younger on several biological aging measures, including inflammatory markers and epigenetic aging signatures. Indeed, Harold has injected E5 into his own right hand and presented differences in the appearance of his right and left hands on social media. Putting pig blood into other animals (and into ourselves!) to reverse biological age might seem like a crazy thing to do. But this idea actually stems from a methodology with a decades-long history called heterochronic parabiosis, an area of research that explores the effects of joining the circulatory systems of different-aged organisms. In this experimental technique, researchers surgically connect two animals, typically mice, of disparate ages so that they share a common bloodstream. This union leads the older and younger individuals to exchange not just blood cells but also signaling molecules, growth factors, and other circulating factors. Remarkably, when an older animal is paired with a younger counterpart, it often experiences improvements in various aspects of health and tissue function, while the younger partner may exhibit corresponding signs of accelerated aging. The mechanisms underlying these effects are complex, multifaceted, and very much still under investigation. In this episode, Matt takes a magnifying glass to E5: what we know about the compound, how it affects lifespan, and how its impact on lifespan stacks up with that of other longevity inventions such as caloric restriction and rapamycin. He discusses whether Harold's recent paper truly proves a reversal of biological age and where his findings fit into https://www.youtube-nocookie.com/embed/ivP3QTyQ2d4 3017 2024-05-07T14:30:17.000Z 2026-10-22T19:54:20.414Z https://longevityharbor.com/en/watch/izxUKRylIhE Video description: fasting, autophagy and aging science explained https://i.ytimg.com/vi/izxUKRylIhE/hqdefault.jpg The description says this Health Decoded episode explains research on fasting, longevity, metabolism, cellular repair, autophagy, insulin sensitivity and inflammation, and how eating patterns may influence aging. It offers no results, numbers or study details. https://www.youtube-nocookie.com/embed/izxUKRylIhE 276 2026-05-06T14:07:25.000Z 2026-10-23T01:12:11.791Z https://longevityharbor.com/de/watch/izxUKRylIhE Videobeschreibung: Fasten, Autophagie und Alternswissenschaft erklärt https://i.ytimg.com/vi/izxUKRylIhE/hqdefault.jpg Laut Beschreibung erklärt diese Health-Decoded-Episode Forschung zu Fasten, Langlebigkeit, Stoffwechsel, Zellreparatur, Autophagie, Insulinempfindlichkeit und Entzündung sowie dazu, wie Essmuster das Altern beeinflussen könnten. Ergebnisse, Zahlen oder Studiendetails nennt sie nicht. https://www.youtube-nocookie.com/embed/izxUKRylIhE 276 2026-05-06T14:07:25.000Z 2026-10-23T01:12:11.791Z https://longevityharbor.com/en/watch/j1lgaAtD0S8 Video description: Thymosin Alpha-1, thymic health and immune aging claims https://i.ytimg.com/vi/j1lgaAtD0S8/hqdefault.jpg The creator describes Thymosin Alpha-1 as a clinically studied immune peptide, cites two 2026 Nature papers on thymic health and mortality in 27,000 adults, and describes personal quarterly and seasonal use. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/j1lgaAtD0S8 2288 2026-09-23T10:30:37.000Z 2026-10-22T21:57:27.391Z https://longevityharbor.com/de/watch/j1lgaAtD0S8 Videobeschreibung: Thymosin Alpha-1, Thymusgesundheit und Aussagen zum Immunaltern https://i.ytimg.com/vi/j1lgaAtD0S8/hqdefault.jpg Die Erstellerin beschreibt Thymosin Alpha-1 als klinisch untersuchtes Immunpeptid, nennt zwei Nature-Arbeiten von 2026 zu Thymusgesundheit und Sterblichkeit bei 27.000 Erwachsenen und beschreibt die eigene vierteljährliche und saisonale Anwendung. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/j1lgaAtD0S8 2288 2026-09-23T10:30:37.000Z 2026-10-22T21:57:27.391Z https://longevityharbor.com/en/watch/j95uznvWy0w Longevity Weekly | Ep. 19 | Hallmarks of Ageing, Chat with Nikhil Yadala, Neurological Disease https://i.ytimg.com/vi/j95uznvWy0w/hqdefault.jpg Longevity Weekly is a short visual newsletter keeping you up-to-date with the latest research reviewed by our Oxford based research team from the world of longevity, wellness and health. Topics discussed in this Longevity Weekly: 00:00 Welcome to Longevity Weekly Ep. 19 00:29 - Hallmarks of Ageing - https://www.gowinglife.com/is-this-why-we-age-a-primer-on-the-hallmarks-of-ageing/ 02:57 - Chat with CEO of Healome, Nikhil Yadala - https://www.youtube.com/watch?v=-INHS9fuN5A 04:50 - Studying Neurological Disease with iPSCs - Part 2 - https://www.gowinglife.com/studying-age-related-neurological-disease-with-induced-pluripotent-stem-cells-part-2-generating-ipscs/ Please subscribe to our channel, and checkout these other articles from our researchers: 1. What Is Telomere Attrition? - https://www.gowinglife.com/is-this-why-we-age-a-primer-on-the-hallmarks-of-ageing/ 2. What Are Epigenetic Alterations? - https://www.gowinglife.com/what-are-epigenetic-alterations-the-hallmarks-of-ageing-series/ https://www.youtube-nocookie.com/embed/j95uznvWy0w 485 2021-06-09T10:14:28.000Z 2026-10-22T17:43:40.134Z https://longevityharbor.com/de/watch/j95uznvWy0w Longevity Weekly | Ep. 19 | Hallmarks of Ageing, Chat with Nikhil Yadala, Neurological Disease https://i.ytimg.com/vi/j95uznvWy0w/hqdefault.jpg Longevity Weekly is a short visual newsletter keeping you up-to-date with the latest research reviewed by our Oxford based research team from the world of longevity, wellness and health. Topics discussed in this Longevity Weekly: 00:00 Welcome to Longevity Weekly Ep. 19 00:29 - Hallmarks of Ageing - https://www.gowinglife.com/is-this-why-we-age-a-primer-on-the-hallmarks-of-ageing/ 02:57 - Chat with CEO of Healome, Nikhil Yadala - https://www.youtube.com/watch?v=-INHS9fuN5A 04:50 - Studying Neurological Disease with iPSCs - Part 2 - https://www.gowinglife.com/studying-age-related-neurological-disease-with-induced-pluripotent-stem-cells-part-2-generating-ipscs/ Please subscribe to our channel, and checkout these other articles from our researchers: 1. What Is Telomere Attrition? - https://www.gowinglife.com/is-this-why-we-age-a-primer-on-the-hallmarks-of-ageing/ 2. What Are Epigenetic Alterations? - https://www.gowinglife.com/what-are-epigenetic-alterations-the-hallmarks-of-ageing-series/ https://www.youtube-nocookie.com/embed/j95uznvWy0w 485 2021-06-09T10:14:28.000Z 2026-10-22T17:43:40.134Z https://longevityharbor.com/en/watch/jAm61shc500 keine MUSKELN = keine BEWEGUNG = STILLSTAND Muskelaufbau Fitness Senioren Muskeltraining Gesundheit https://i.ytimg.com/vi/jAm61shc500/hqdefault.jpg Dem ALTERN mit MUSKELKRAFT, FITNESS und gesunder Lebensweise, aber auch mit der Hilfe sorgfältig ausgesuchter Nährstoffsupplementen kraftvoll Widerstand leisten. Das waren und sind über viele Jahrzehnte hinweg nur einige Bausteine unseres Bestrebens, auch der natürlichen Angst vor dem ÄLTERWERDEN etwas entgegenzusetzen. Es war nie unser Bestreben, auf diese Weise etwa unser Leben, wie auch immer, verlängern zu wollen. Im Vordergrund stand immer der Wille, unser Leben aktiv und sinnvoll gestalten zu wollen. Dazu braucht es einen gesunden Körper und einen gesunden Geist. Dieses dem einen oder anderen Zuschauer vermitteln zu dürfen, ist Sinn und Zweck unseres Kanals, auch im hohen Alter noch von 88 und 86 Jahren Verwendete GRAFIKEN und HINTERGRÜNDE sind teilweise von FREEPIC, ISTOCK, PIXABAY (lizenzierte Inhalte) entnommen worden. Vielen Dank. #FitnessimAlter #Senioren #Seniorenfitness #MuskelaufbauimAlter #Gesundhalten #BewegungimAlter #Krafttraining #KrafttrainingimAlter #Fitab50 #Fitab60 #Fitab70 #Bizeps #trizeps #Hanteln #Hanteltraining #Schwingstab #HantelnimAlter #Gesundheit https://www.youtube-nocookie.com/embed/jAm61shc500 586 2025-07-03T16:04:45.000Z 2026-10-22T17:43:36.082Z https://longevityharbor.com/de/watch/jAm61shc500 keine MUSKELN = keine BEWEGUNG = STILLSTAND Muskelaufbau Fitness Senioren Muskeltraining Gesundheit https://i.ytimg.com/vi/jAm61shc500/hqdefault.jpg Dem ALTERN mit MUSKELKRAFT, FITNESS und gesunder Lebensweise, aber auch mit der Hilfe sorgfältig ausgesuchter Nährstoffsupplementen kraftvoll Widerstand leisten. Das waren und sind über viele Jahrzehnte hinweg nur einige Bausteine unseres Bestrebens, auch der natürlichen Angst vor dem ÄLTERWERDEN etwas entgegenzusetzen. Es war nie unser Bestreben, auf diese Weise etwa unser Leben, wie auch immer, verlängern zu wollen. Im Vordergrund stand immer der Wille, unser Leben aktiv und sinnvoll gestalten zu wollen. Dazu braucht es einen gesunden Körper und einen gesunden Geist. Dieses dem einen oder anderen Zuschauer vermitteln zu dürfen, ist Sinn und Zweck unseres Kanals, auch im hohen Alter noch von 88 und 86 Jahren Verwendete GRAFIKEN und HINTERGRÜNDE sind teilweise von FREEPIC, ISTOCK, PIXABAY (lizenzierte Inhalte) entnommen worden. Vielen Dank. #FitnessimAlter #Senioren #Seniorenfitness #MuskelaufbauimAlter #Gesundhalten #BewegungimAlter #Krafttraining #KrafttrainingimAlter #Fitab50 #Fitab60 #Fitab70 #Bizeps #trizeps #Hanteln #Hanteltraining #Schwingstab #HantelnimAlter #Gesundheit https://www.youtube-nocookie.com/embed/jAm61shc500 586 2025-07-03T16:04:45.000Z 2026-10-22T17:43:36.082Z https://longevityharbor.com/en/watch/jCbfP18vPrc Wall exercises for people over 60: description-only overview https://i.ytimg.com/vi/jCbfP18vPrc/hqdefault.jpg The description presents five wall exercises for generally healthy people aged 60 and older, said to train leg muscles, strength and balance for everyday movements; no results are reported. https://www.youtube-nocookie.com/embed/jCbfP18vPrc 700 2026-09-25T14:00:03.000Z 2026-10-22T21:50:22.600Z https://longevityharbor.com/de/watch/jCbfP18vPrc Wandübungen für Menschen über 60: reine Beschreibungsübersicht https://i.ytimg.com/vi/jCbfP18vPrc/hqdefault.jpg Die Beschreibung stellt fünf Wandübungen für allgemein gesunde Menschen ab 60 vor, die Beinmuskeln, Kraft und Balance für Alltagsbewegungen trainieren sollen; Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/jCbfP18vPrc 700 2026-09-25T14:00:03.000Z 2026-10-22T21:50:22.600Z https://longevityharbor.com/en/watch/jEsIuhAPHB4 Epigenetic clocks: how DNA methylation is used to estimate biological age https://i.ytimg.com/vi/jEsIuhAPHB4/hqdefault.jpg A video description explains how epigenetic clocks use DNA methylation patterns to estimate biological age, how first- to third-generation clocks differ, and that accelerated epigenetic age is associated with higher disease and mortality risk. Different clocks can disagree, and there is no single gold standard. https://www.youtube-nocookie.com/embed/jEsIuhAPHB4 1349 2026-10-22T14:59:04.000Z 2026-10-22T19:34:03.819Z https://longevityharbor.com/de/watch/jEsIuhAPHB4 Epigenetische Uhren: Wie DNA-Methylierung das biologische Alter schätzen soll https://i.ytimg.com/vi/jEsIuhAPHB4/hqdefault.jpg Eine Videobeschreibung erklärt, wie epigenetische Uhren DNA-Methylierungsmuster nutzen, um das biologische Alter zu schätzen, wie sich Uhren der ersten bis dritten Generation unterscheiden und dass beschleunigtes epigenetisches Alter mit höherem Krankheits- und Sterberisiko assoziiert ist. Verschiedene Uhren können voneinander abweichen; einen einheitlichen Goldstandard gibt es nicht. https://www.youtube-nocookie.com/embed/jEsIuhAPHB4 1349 2026-10-22T14:59:04.000Z 2026-10-22T19:34:03.819Z https://longevityharbor.com/en/watch/jGvlFllHeTk Gladden describes biological age testing and longevity mindset in a video https://i.ytimg.com/vi/jGvlFllHeTk/hqdefault.jpg In this video description, Dr. Jeffrey Gladden, an interventional cardiologist and founder of Gladden Longevity, describes biological age testing, longevity science and mindset strategies aimed at helping people stay younger longer. https://www.youtube-nocookie.com/embed/jGvlFllHeTk 2437 2026-06-11T12:00:34.000Z 2026-10-23T00:00:13.761Z https://longevityharbor.com/de/watch/jGvlFllHeTk Gladden beschreibt in einem Video biologisches Alter und Longevity-Mindset https://i.ytimg.com/vi/jGvlFllHeTk/hqdefault.jpg In dieser Videobeschreibung beschreibt Dr. Jeffrey Gladden, interventioneller Kardiologe und Gründer von Gladden Longevity, Tests zum biologischen Alter, Longevity-Wissenschaft und Mindset-Strategien mit dem Ziel, Menschen länger jung zu halten. https://www.youtube-nocookie.com/embed/jGvlFllHeTk 2437 2026-06-11T12:00:34.000Z 2026-10-23T00:00:13.761Z https://longevityharbor.com/en/watch/jHjncDTYX60 Not advice — just what I learned after actually researching NMN vs NAD⁺ https://i.ytimg.com/vi/jHjncDTYX60/hqdefault.jpg Not advice — just what I learned after actually researching NMN vs NAD⁺. If you’re curious, grab yours before it’s “trending.” Live Well #nmn #nmnsupplement #nadsupplement #tiktokshopcreatorpicks #cellularhealth https://www.youtube-nocookie.com/embed/jHjncDTYX60 155 2026-01-11T22:38:48.000Z 2026-10-22T19:32:37.712Z https://longevityharbor.com/de/watch/jHjncDTYX60 Not advice — just what I learned after actually researching NMN vs NAD⁺ https://i.ytimg.com/vi/jHjncDTYX60/hqdefault.jpg Not advice — just what I learned after actually researching NMN vs NAD⁺. If you’re curious, grab yours before it’s “trending.” Live Well #nmn #nmnsupplement #nadsupplement #tiktokshopcreatorpicks #cellularhealth https://www.youtube-nocookie.com/embed/jHjncDTYX60 155 2026-01-11T22:38:48.000Z 2026-10-22T19:32:37.712Z https://longevityharbor.com/en/watch/jIc4jcM5FEc Archive: Geroscience Approaches to Health: New Therapies for Mitochondrial Disorders https://i.ytimg.com/vi/jIc4jcM5FEc/hqdefault.jpg Geroscience studies how biological aging causes and affects chronic age-related diseases and conditions with the goal to improve quality of life in the elderly. Fundamental biological processes (codified in 9 “hallmarks” of aging) drive both age-dependent and independent disorders. Thus, it could be argued that the biology of aging equates with the biology of health. Following this premise, this lecture explores how geroscience can help us understand and develop novel therapies for pediatric mitochondrial disorders, with a particular focus on the antidiabetic drug acarbose and its effects on the intestinal microbiome. Alessandro Bitto, PhD Acting Assistant Professor Department of Laboratory Medicine & Pathology University of Washington The University of Washington is committed to ensuring digital accessibility in our services, programs, and activities. If you encounter accessibility barriers using videos found on this channel, please contact UW Video at uwvideo [at] uw [dot] edu. https://www.youtube-nocookie.com/embed/jIc4jcM5FEc 2812 2022-10-17T22:02:39.000Z 2026-10-22T17:43:40.180Z https://longevityharbor.com/de/watch/jIc4jcM5FEc Archive: Geroscience Approaches to Health: New Therapies for Mitochondrial Disorders https://i.ytimg.com/vi/jIc4jcM5FEc/hqdefault.jpg Geroscience studies how biological aging causes and affects chronic age-related diseases and conditions with the goal to improve quality of life in the elderly. Fundamental biological processes (codified in 9 “hallmarks” of aging) drive both age-dependent and independent disorders. Thus, it could be argued that the biology of aging equates with the biology of health. Following this premise, this lecture explores how geroscience can help us understand and develop novel therapies for pediatric mitochondrial disorders, with a particular focus on the antidiabetic drug acarbose and its effects on the intestinal microbiome. Alessandro Bitto, PhD Acting Assistant Professor Department of Laboratory Medicine & Pathology University of Washington The University of Washington is committed to ensuring digital accessibility in our services, programs, and activities. If you encounter accessibility barriers using videos found on this channel, please contact UW Video at uwvideo [at] uw [dot] edu. https://www.youtube-nocookie.com/embed/jIc4jcM5FEc 2812 2022-10-17T22:02:39.000Z 2026-10-22T17:43:40.180Z https://longevityharbor.com/en/watch/jJ0uKzH_tNk Judy Campisi: Understanding Senescence https://i.ytimg.com/vi/jJ0uKzH_tNk/hqdefault.jpg Dr. Campisi has been at the forefront of studying cellular senescence for decades, revealing the mysteries of these not-exactly-dead cells and their role in many diseases of aging. In this episode, she joins her colleague Gordon to discuss the characteristics and function of senescent cells, as well as promising interventions on the horizon. Judy also describes how to get lucky in science by being prepared to see the unexpected. Support the show (https://www.buckinstitute.org/donate/) https://www.youtube-nocookie.com/embed/jJ0uKzH_tNk 2746 2024-03-20T21:20:42.000Z 2026-10-22T18:43:13.595Z https://longevityharbor.com/de/watch/jJ0uKzH_tNk Judy Campisi: Understanding Senescence https://i.ytimg.com/vi/jJ0uKzH_tNk/hqdefault.jpg Dr. Campisi has been at the forefront of studying cellular senescence for decades, revealing the mysteries of these not-exactly-dead cells and their role in many diseases of aging. In this episode, she joins her colleague Gordon to discuss the characteristics and function of senescent cells, as well as promising interventions on the horizon. Judy also describes how to get lucky in science by being prepared to see the unexpected. Support the show (https://www.buckinstitute.org/donate/) https://www.youtube-nocookie.com/embed/jJ0uKzH_tNk 2746 2024-03-20T21:20:42.000Z 2026-10-22T18:43:13.595Z https://longevityharbor.com/en/watch/jKKi2wr3AhU Are You Taking NAD+ at The Right Time? ⏰🤔 #peptides https://i.ytimg.com/vi/jKKi2wr3AhU/hqdefault.jpg Book your free discovery call HERE: https://drjonesdc.com/yt1d Taking NAD+ at the wrong time can blunt results. Research shows NAD+ and NMN work best in a fasted state, improving insulin signaling, fat metabolism, energy, and autophagy. Learn the optimal timing, fasting strategy, and why consistency matters for real metabolic benefits. https://www.youtube-nocookie.com/embed/jKKi2wr3AhU 100 2025-11-14T21:01:19.000Z 2026-10-22T19:32:38.565Z https://longevityharbor.com/de/watch/jKKi2wr3AhU Are You Taking NAD+ at The Right Time? ⏰🤔 #peptides https://i.ytimg.com/vi/jKKi2wr3AhU/hqdefault.jpg Book your free discovery call HERE: https://drjonesdc.com/yt1d Taking NAD+ at the wrong time can blunt results. Research shows NAD+ and NMN work best in a fasted state, improving insulin signaling, fat metabolism, energy, and autophagy. Learn the optimal timing, fasting strategy, and why consistency matters for real metabolic benefits. https://www.youtube-nocookie.com/embed/jKKi2wr3AhU 100 2025-11-14T21:01:19.000Z 2026-10-22T19:32:38.565Z https://longevityharbor.com/en/watch/jLHYAlNM048 The Role of NMN in Ageing, Health and Longevity: What Is Known? https://i.ytimg.com/vi/jLHYAlNM048/hqdefault.jpg An educational overview of NMN and what is currently known about its possible role in ageing, health and longevity. It supports further study and does not replace individual medical advice or current clinical guidance. Continue your learning with this related London HeartbeatsZ Academy course: Diploma in Longevity Medicine https://heartbeatsz.com/courses/diploma-in-longevity-medicine/ Explore the course and enrol in related learning, with subscriptions starting from £9/month. Check the course page and subscription details for access options. For education only, not individual medical advice. Follow current guidance and local protocols. Discover more courses: https://heartbeatsz.com/ Join this channel to get access to perks: https://www.youtube.com/channel/UCmsqcvTONEgPxEVHWLsM9tQ/join #NMN #Longevity #HealthyAgeing #HeartbeatsZ #drnarendrakumar https://www.youtube-nocookie.com/embed/jLHYAlNM048 248 2024-10-25T14:00:25.000Z 2026-10-22T19:04:42.888Z https://longevityharbor.com/de/watch/jLHYAlNM048 The Role of NMN in Ageing, Health and Longevity: What Is Known? https://i.ytimg.com/vi/jLHYAlNM048/hqdefault.jpg An educational overview of NMN and what is currently known about its possible role in ageing, health and longevity. It supports further study and does not replace individual medical advice or current clinical guidance. Continue your learning with this related London HeartbeatsZ Academy course: Diploma in Longevity Medicine https://heartbeatsz.com/courses/diploma-in-longevity-medicine/ Explore the course and enrol in related learning, with subscriptions starting from £9/month. Check the course page and subscription details for access options. For education only, not individual medical advice. Follow current guidance and local protocols. Discover more courses: https://heartbeatsz.com/ Join this channel to get access to perks: https://www.youtube.com/channel/UCmsqcvTONEgPxEVHWLsM9tQ/join #NMN #Longevity #HealthyAgeing #HeartbeatsZ #drnarendrakumar https://www.youtube-nocookie.com/embed/jLHYAlNM048 248 2024-10-25T14:00:25.000Z 2026-10-22T19:04:42.888Z https://longevityharbor.com/en/watch/jM89tcxb4eU The Longevity/Anti-Aging Supplements that ACTUALLY work https://i.ytimg.com/vi/jM89tcxb4eU/hqdefault.jpg Welcome back :) In todays video I share 6 Longevity supplements, which are not just backed by science, but fromhttps://youtu.be/lRndPfwo2Og?si=SoI0FQPpgSwQNzTT which I can actually fell a noticeable difference from You may also enjoy: My experience with taking 3x the recommended dosage of creatine Here is my supplement playlist https://youtube.com/playlist?list=PLlcIMqor2xVIzhLmJIxWEjhMrmNzWmnfZ&si=nikzIVvd3ZSj1k7z Supplements mentioned: NMN https://donotage.org/pure-nmn You can use code Claudia to get 10% off on anything on this site Creatine https://donotage.org/creatine You can use code Claudia to get 10% off on anything on this site High Molecular Weight HA https://donotage.org/pure-hyaluronic-acid You can use code Claudia to get 10% off on anything on this site Omega 3 https://www.vitacost.com/barleans-vegan-omegawith-flax-algae-oil?&CSRC=GPF-PA-705875802185-google_shopping_pmax_x_us_vitamins+%26+supplements-&network=x&keywordname=&device=c&adid=&matchtype=&gclick=CjwKCAjwu9fHBhAWEiwAzGRC_6_TpFvMhBJSGxpKgzv3xJrjhjRARqVEyulD4hXUr9HLKEAXMfA_BhoCTSAQAvD_BwE&ds_agid=&targetid=&gclsrc=aw.ds&gad_source=1&gad_campaignid=22903761986&gbraid=0AAAAADzrQKt_RsdlXOC4q_Q0NTXvYg20J&gclid=CjwKCAjwu9fHBhAWEiwAzGRC_6_TpFvMhBJSGxpKgzv3xJrjhjRARqVEyulD4hXUr9HLKEAXMfA_BhoCTSAQAvD_BwE Magnesium https://www.iherb.com/pr/sports-research-magnesium-glycinate-90-veggie-capsules-80-mg-per-capsule/146012?gad_campaignid=400306152&gad_source=1&gclid=CjwKCAjwu9fHBhAWEiwAzGRC_5NhfoHHlK9Gub8IJdtrCYTmMhOmP-xNJAAt72Wyb7X8JU71QUz2eRoC9HcQAvD_BwE B12 https://www.iherb.com/pr/maryruth-s-organic-methyl-b12-liquid-spray-berry-1-500-mcg-1-fl-oz-30-ml/110346?gad_campaignid=400306152&gad_source=1&gclid=CjwKCAjwu9fHBhAWEiwAzGRC_0sPGaLdU49IFTE6aJil5XaAsa9LHqoM0faTBJUAzSsDpNRSBA0mMxoCyE8QAvD_BwE IMPORTANT NOTICE This content is for informational and entertainment purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult qualified healthcare professionals before making any health, medical, or treatment decisions o https://www.youtube-nocookie.com/embed/jM89tcxb4eU 1452 2025-10-21T14:01:09.000Z 2026-10-22T18:43:09.908Z https://longevityharbor.com/de/watch/jM89tcxb4eU The Longevity/Anti-Aging Supplements that ACTUALLY work https://i.ytimg.com/vi/jM89tcxb4eU/hqdefault.jpg Welcome back :) In todays video I share 6 Longevity supplements, which are not just backed by science, but fromhttps://youtu.be/lRndPfwo2Og?si=SoI0FQPpgSwQNzTT which I can actually fell a noticeable difference from You may also enjoy: My experience with taking 3x the recommended dosage of creatine Here is my supplement playlist https://youtube.com/playlist?list=PLlcIMqor2xVIzhLmJIxWEjhMrmNzWmnfZ&si=nikzIVvd3ZSj1k7z Supplements mentioned: NMN https://donotage.org/pure-nmn You can use code Claudia to get 10% off on anything on this site Creatine https://donotage.org/creatine You can use code Claudia to get 10% off on anything on this site High Molecular Weight HA https://donotage.org/pure-hyaluronic-acid You can use code Claudia to get 10% off on anything on this site Omega 3 https://www.vitacost.com/barleans-vegan-omegawith-flax-algae-oil?&CSRC=GPF-PA-705875802185-google_shopping_pmax_x_us_vitamins+%26+supplements-&network=x&keywordname=&device=c&adid=&matchtype=&gclick=CjwKCAjwu9fHBhAWEiwAzGRC_6_TpFvMhBJSGxpKgzv3xJrjhjRARqVEyulD4hXUr9HLKEAXMfA_BhoCTSAQAvD_BwE&ds_agid=&targetid=&gclsrc=aw.ds&gad_source=1&gad_campaignid=22903761986&gbraid=0AAAAADzrQKt_RsdlXOC4q_Q0NTXvYg20J&gclid=CjwKCAjwu9fHBhAWEiwAzGRC_6_TpFvMhBJSGxpKgzv3xJrjhjRARqVEyulD4hXUr9HLKEAXMfA_BhoCTSAQAvD_BwE Magnesium https://www.iherb.com/pr/sports-research-magnesium-glycinate-90-veggie-capsules-80-mg-per-capsule/146012?gad_campaignid=400306152&gad_source=1&gclid=CjwKCAjwu9fHBhAWEiwAzGRC_5NhfoHHlK9Gub8IJdtrCYTmMhOmP-xNJAAt72Wyb7X8JU71QUz2eRoC9HcQAvD_BwE B12 https://www.iherb.com/pr/maryruth-s-organic-methyl-b12-liquid-spray-berry-1-500-mcg-1-fl-oz-30-ml/110346?gad_campaignid=400306152&gad_source=1&gclid=CjwKCAjwu9fHBhAWEiwAzGRC_0sPGaLdU49IFTE6aJil5XaAsa9LHqoM0faTBJUAzSsDpNRSBA0mMxoCyE8QAvD_BwE IMPORTANT NOTICE This content is for informational and entertainment purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult qualified healthcare professionals before making any health, medical, or treatment decisions o https://www.youtube-nocookie.com/embed/jM89tcxb4eU 1452 2025-10-21T14:01:09.000Z 2026-10-22T18:43:09.908Z https://longevityharbor.com/en/watch/jNxlJep1FfY Dr. Brian Kennedy on rapamycin, mTOR and anti-aging trial hurdles https://i.ytimg.com/vi/jNxlJep1FfY/hqdefault.jpg In this video description, Dr. Brian Kennedy says rapamycin may extend lifespan by inhibiting mTOR, that intermittent low-dose regimens may reduce side effects versus continuous use, and that aging trials face reimbursement hurdles. https://www.youtube-nocookie.com/embed/jNxlJep1FfY 488 2026-09-25T07:01:38.000Z 2026-10-22T21:50:54.526Z https://longevityharbor.com/de/watch/jNxlJep1FfY Dr. Brian Kennedy über Rapamycin, mTOR und Hürden bei Alternsstudien https://i.ytimg.com/vi/jNxlJep1FfY/hqdefault.jpg In dieser Videobeschreibung sagt Dr. Brian Kennedy, Rapamycin könne durch Hemmung von mTOR die Lebensspanne verlängern, intermittierende niedrige Dosen könnten Nebenwirkungen gegenüber Daueranwendung verringern, und Alternsstudien stießen auf Erstattungshürden. https://www.youtube-nocookie.com/embed/jNxlJep1FfY 488 2026-09-25T07:01:38.000Z 2026-10-22T21:50:54.526Z https://longevityharbor.com/en/watch/jQz0t-r0cG4 Description of a podcast on measuring and modifying biological age https://i.ytimg.com/vi/jQz0t-r0cG4/hqdefault.jpg The description presents a podcast episode with Dr. Jesse Poganik on how biological age is measured, what it reflects, and whether it can be changed; it states that measurement is not yet intervention. https://www.youtube-nocookie.com/embed/jQz0t-r0cG4 2659 2026-05-04T16:01:15.000Z 2026-10-23T01:19:07.152Z https://longevityharbor.com/de/watch/jQz0t-r0cG4 Beschreibung eines Podcasts über Messung und Veränderung des biologischen Alters https://i.ytimg.com/vi/jQz0t-r0cG4/hqdefault.jpg Die Beschreibung stellt eine Podcast-Folge mit Dr. Jesse Poganik vor: wie biologisches Alter gemessen wird, was es widerspiegelt und ob es verändert werden kann; Messung sei noch keine Intervention. https://www.youtube-nocookie.com/embed/jQz0t-r0cG4 2659 2026-05-04T16:01:15.000Z 2026-10-23T01:19:07.152Z https://longevityharbor.com/en/watch/jRCQwYGxFhI Understanding Fasting Insights for Perimenopausal Women with Dr. Stacy Sims https://i.ytimg.com/vi/jRCQwYGxFhI/hqdefault.jpg Check out our full podcast episode on Female Fitness and Nutrition During Menstruation and Menopause with Dr. Stacy Sims here: https://youtu.be/NXwa3vyFxws https://www.youtube-nocookie.com/embed/jRCQwYGxFhI 91 2025-04-08T21:25:04.000Z 2026-10-22T19:54:18.272Z https://longevityharbor.com/de/watch/jRCQwYGxFhI Understanding Fasting Insights for Perimenopausal Women with Dr. Stacy Sims https://i.ytimg.com/vi/jRCQwYGxFhI/hqdefault.jpg Check out our full podcast episode on Female Fitness and Nutrition During Menstruation and Menopause with Dr. Stacy Sims here: https://youtu.be/NXwa3vyFxws https://www.youtube-nocookie.com/embed/jRCQwYGxFhI 91 2025-04-08T21:25:04.000Z 2026-10-22T19:54:18.272Z https://longevityharbor.com/en/watch/jShvmXxjM3U Integrative Hallmarks https://i.ytimg.com/vi/jShvmXxjM3U/hqdefault.jpg Why do we die? And how do we slow your aging? Time to learn about the Integrative Hallmarks of Aging. There are 12 Hallmarks of Aging — the key reasons our bodies decline over time. Today, we’re diving into one of the most fascinating categories: Integrative Hallmarks. Dr. Tim, one of the world’s foremost experts in longevity, breaks down these hallmarks of aging: • Dysbiosis → how our microbiome changes with age, impacting immunity and metabolism • Chronic inflammation → the silent driver of many age-related diseases • Altered intercellular communication → the way our cells talk (or fail to) as we get older • Stem cell exhaustion → the decline of the very cells that keep us youthful and regenerative The exciting part? These aren’t just theoretical. We already have ways to intervene: • Optimizing the microbiome with food, probiotics, and prebiotics • Tackling inflammation through lifestyle and medical approaches • Looking ahead to breakthroughs like gene editing of stem cells to potentially reverse aging itself This is the intersection of longevity medicine, biohacking, and fulfillment — practical science you can apply today to live your longest, healthiest, and most vibrant life. #AFulfilledLife #TimCookMD #UnlimitedLife #MarcKielburger #HallmarksofAging -------------------------------------------------------------------------------------- Marc Kielburger: Social Entrepreneur, Biohacking Advocate, and Legacy Architect Marc Kielburger is a husband, father, and internationally recognized social entrepreneur with over 30 years of experience empowering people and organizations to live with purpose. A passionate advocate for biohacking, longevity medicine, and human consciousness, Marc blends science and spirituality to help others achieve fulfilled, meaningful lives. https://www.youtube-nocookie.com/embed/jShvmXxjM3U 90 2025-08-29T13:28:29.000Z 2026-10-22T19:43:46.580Z https://longevityharbor.com/de/watch/jShvmXxjM3U Integrative Hallmarks https://i.ytimg.com/vi/jShvmXxjM3U/hqdefault.jpg Why do we die? And how do we slow your aging? Time to learn about the Integrative Hallmarks of Aging. There are 12 Hallmarks of Aging — the key reasons our bodies decline over time. Today, we’re diving into one of the most fascinating categories: Integrative Hallmarks. Dr. Tim, one of the world’s foremost experts in longevity, breaks down these hallmarks of aging: • Dysbiosis → how our microbiome changes with age, impacting immunity and metabolism • Chronic inflammation → the silent driver of many age-related diseases • Altered intercellular communication → the way our cells talk (or fail to) as we get older • Stem cell exhaustion → the decline of the very cells that keep us youthful and regenerative The exciting part? These aren’t just theoretical. We already have ways to intervene: • Optimizing the microbiome with food, probiotics, and prebiotics • Tackling inflammation through lifestyle and medical approaches • Looking ahead to breakthroughs like gene editing of stem cells to potentially reverse aging itself This is the intersection of longevity medicine, biohacking, and fulfillment — practical science you can apply today to live your longest, healthiest, and most vibrant life. #AFulfilledLife #TimCookMD #UnlimitedLife #MarcKielburger #HallmarksofAging -------------------------------------------------------------------------------------- Marc Kielburger: Social Entrepreneur, Biohacking Advocate, and Legacy Architect Marc Kielburger is a husband, father, and internationally recognized social entrepreneur with over 30 years of experience empowering people and organizations to live with purpose. A passionate advocate for biohacking, longevity medicine, and human consciousness, Marc blends science and spirituality to help others achieve fulfilled, meaningful lives. https://www.youtube-nocookie.com/embed/jShvmXxjM3U 90 2025-08-29T13:28:29.000Z 2026-10-22T19:43:46.580Z https://longevityharbor.com/en/watch/jU980zgED80 Sleep and aging: what the video description says https://i.ytimg.com/vi/jU980zgED80/hqdefault.jpg The description says the video explains in plain language how sleep may relate to recovery, metabolism, blood pressure, inflammation, memory and repair signals, without miracle claims. It does not report telomere results. https://www.youtube-nocookie.com/embed/jU980zgED80 106 2026-06-26T20:00:50.000Z 2026-10-22T23:47:58.738Z https://longevityharbor.com/de/watch/jU980zgED80 Schlaf und Altern: Was die Videobeschreibung sagt https://i.ytimg.com/vi/jU980zgED80/hqdefault.jpg Laut Beschreibung erklärt das Video in einfacher Sprache, wie Schlaf mit Erholung, Stoffwechsel, Blutdruck, Entzündung, Gedächtnis und Reparatursignalen zusammenhängen könnte – ohne Wunderversprechen. Telomer-Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/jU980zgED80 106 2026-06-26T20:00:50.000Z 2026-10-22T23:47:58.738Z https://longevityharbor.com/en/watch/j_WyUXVezqc Video description: Dr. William Li on foods and habits said to target aging hallmarks https://i.ytimg.com/vi/j_WyUXVezqc/hqdefault.jpg In this video description, Dr. William Li presents simple foods and daily habits as ways to influence the hallmarks of aging, including inflammation, DNA damage, mitochondria and stem cells. The description names six foods and a 12-hour fasting window; it reports no study results. https://www.youtube-nocookie.com/embed/j_WyUXVezqc 1438 2026-03-28T12:00:00.000Z 2026-10-23T01:51:40.352Z https://longevityharbor.com/de/watch/j_WyUXVezqc Videobeschreibung: Dr. William Li über Lebensmittel und Gewohnheiten gegen Altersmerkmale https://i.ytimg.com/vi/j_WyUXVezqc/hqdefault.jpg In dieser Videobeschreibung stellt Dr. William Li einfache Lebensmittel und Alltagsgewohnheiten als Wege vor, die Altersmerkmale zu beeinflussen, darunter Entzündung, DNA-Schäden, Mitochondrien und Stammzellen. Die Beschreibung nennt sechs Lebensmittel und ein 12-Stunden-Fastenfenster; Studienergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/j_WyUXVezqc 1438 2026-03-28T12:00:00.000Z 2026-10-23T01:51:40.352Z https://longevityharbor.com/en/watch/j_wHOkhieHs Video description: historical 'first and second sleep' and varied sleep in hunter-gatherer studies https://i.ytimg.com/vi/j_wHOkhieHs/hqdefault.jpg The description says historical sources describe a split 'first sleep' and 'second sleep', but modern hunter-gatherer studies show no single ancient pattern; individual chronotype differences may aid group vigilance. https://www.youtube-nocookie.com/embed/j_wHOkhieHs 101 2026-09-17T21:07:22.000Z 2026-10-22T22:05:20.813Z https://longevityharbor.com/de/watch/j_wHOkhieHs Videobeschreibung: historischer 'erster und zweiter Schlaf' und variabler Schlaf in Jäger-und-Sammle https://i.ytimg.com/vi/j_wHOkhieHs/hqdefault.jpg Laut Beschreibung nennen historische Quellen einen geteilten 'ersten und zweiten Schlaf', doch moderne Jäger-und-Sammler-Studien zeigen kein einheitliches altes Muster; Unterschiede im Chronotyp könnten der Gruppe Wachsamkeit bieten. https://www.youtube-nocookie.com/embed/j_wHOkhieHs 101 2026-09-17T21:07:22.000Z 2026-10-22T22:05:20.813Z https://longevityharbor.com/en/watch/ja-3UAAoAUc UTHSCSA Barshop Institute: Rapamycin Profile https://i.ytimg.com/vi/ja-3UAAoAUc/hqdefault.jpg Scientists at the Barshop Institute speak on the exciting scientific breakthroughs from studies of rapamycin in aging research. https://www.youtube-nocookie.com/embed/ja-3UAAoAUc 331 2012-06-26T15:29:45.000Z 2026-10-22T17:43:41.743Z https://longevityharbor.com/de/watch/ja-3UAAoAUc UTHSCSA Barshop Institute: Rapamycin Profile https://i.ytimg.com/vi/ja-3UAAoAUc/hqdefault.jpg Scientists at the Barshop Institute speak on the exciting scientific breakthroughs from studies of rapamycin in aging research. https://www.youtube-nocookie.com/embed/ja-3UAAoAUc 331 2012-06-26T15:29:45.000Z 2026-10-22T17:43:41.743Z https://longevityharbor.com/en/watch/jbAUR9Cg8MU Talk on cellular senescence and ECM remodeling in pelvic organ prolapse https://i.ytimg.com/vi/jbAUR9Cg8MU/hqdefault.jpg The description announces a talk by Maria Florian-Rodriguez, MD, on cellular senescence and extracellular matrix remodeling in pelvic organ prolapse, given within a research interest group's monthly knowledge exchange. The description gives no study results. https://www.youtube-nocookie.com/embed/jbAUR9Cg8MU 1786 2026-05-06T20:00:12.000Z 2026-10-23T01:07:33.757Z https://longevityharbor.com/de/watch/jbAUR9Cg8MU Vortrag über Zellalterung und Umbau der Extrazellulärmatrix beim Beckenorganvorfall https://i.ytimg.com/vi/jbAUR9Cg8MU/hqdefault.jpg Die Beschreibung kündigt einen Vortrag von Maria Florian-Rodriguez, MD, über zelluläre Seneszenz und Umbau der Extrazellulärmatrix beim Beckenorganvorfall an, gehalten im Rahmen des monatlichen Wissensaustauschs einer Forschungsgruppe. Ergebnisse nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/jbAUR9Cg8MU 1786 2026-05-06T20:00:12.000Z 2026-10-23T01:07:33.757Z https://longevityharbor.com/en/watch/jbOgGF_Wdvw Video description claims exercise, not NMN or NR, best raises muscle NAD https://i.ytimg.com/vi/jbOgGF_Wdvw/hqdefault.jpg The description says emerging human data suggest NMN and NR can raise NAD in blood but often not in muscle, and that a study comparing sedentary older adults with Olympic-level athletes found the highest muscle NAD in the athlete group using a lifestyle protocol. These are creator claims from the description only. https://www.youtube-nocookie.com/embed/jbOgGF_Wdvw 1011 2026-02-23T13:58:49.000Z 2026-10-23T02:25:49.318Z https://longevityharbor.com/de/watch/jbOgGF_Wdvw Videobeschreibung: Sport statt NMN oder NR soll Muskel-NAD am besten steigern https://i.ytimg.com/vi/jbOgGF_Wdvw/hqdefault.jpg Die Beschreibung sagt, neue Humandaten legten nahe, dass NMN und NR NAD im Blut, oft aber nicht im Muskel erhöhen, und eine Studie mit sesshaften älteren Erwachsenen und Olympiasportlern habe das höchste Muskel-NAD in der Sportlergruppe mit einem Lebensstil-Protokoll gefunden. Das sind Aussagen des Erstellers aus der Beschreibung. https://www.youtube-nocookie.com/embed/jbOgGF_Wdvw 1011 2026-02-23T13:58:49.000Z 2026-10-23T02:25:49.318Z https://longevityharbor.com/en/watch/jgaoLdS82vw Build Muscle Size, Increase Strength & Improve Recovery | Huberman Lab Essentials https://i.ytimg.com/vi/jgaoLdS82vw/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this Huberman Lab Essentials episode, I discuss how to build muscle strength and size (hypertrophy) and cover key training principles to enhance athletic performance and offset age-related muscle decline. I explain how the nervous system drives muscle movement, the key differences between training for hypertrophy or strength, and resistance training protocols to build muscle for performance and healthy aging. Additionally, I discuss tools for assessing recovery and the role of key nutrients—such as creatine and electrolytes—in supporting muscle development and performance. This episode provides actionable, science-backed strategies to enhance movement, preserve strength with age, and boost energy levels. Episode show notes: https://go.hubermanlab.com/sPY0glv Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/XLr2RKoD-oY Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S *Timestamps* 00:00:00 Huberman Lab Essentials; Muscle 00:02:02 Muscle & Nervous System 00:03:24 Strength & Aging, Henneman's Size Principle, Use Heavy Weights? 00:07:30 3 Stimuli, Muscle Strength vs Muscle Growth (Hypertrophy) 00:09:31 Tool: Resistance Training Protocol, Increase Muscle Strength 00:13:16 Tool: Advanced Resistance Training & Volume; Speed, Rest 00:16:17 Testing for Recovery, Heart Rate Variability, Grip Strength 00:19:54 Testing for Recovery, Carbon Dioxide Tolerance 00:22:51 Ice Bath Timing; NSAIDs & Exercise 00:24:06 Salt & Electrolytes; Creatine; Leucine #HubermanLab #Science #MuscleGrowth #Strength Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer https://www.youtube-nocookie.com/embed/jgaoLdS82vw 1669 2025-04-10T12:01:11.000Z 2026-10-22T19:21:29.716Z https://longevityharbor.com/de/watch/jgaoLdS82vw Build Muscle Size, Increase Strength & Improve Recovery | Huberman Lab Essentials https://i.ytimg.com/vi/jgaoLdS82vw/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this Huberman Lab Essentials episode, I discuss how to build muscle strength and size (hypertrophy) and cover key training principles to enhance athletic performance and offset age-related muscle decline. I explain how the nervous system drives muscle movement, the key differences between training for hypertrophy or strength, and resistance training protocols to build muscle for performance and healthy aging. Additionally, I discuss tools for assessing recovery and the role of key nutrients—such as creatine and electrolytes—in supporting muscle development and performance. This episode provides actionable, science-backed strategies to enhance movement, preserve strength with age, and boost energy levels. Episode show notes: https://go.hubermanlab.com/sPY0glv Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/XLr2RKoD-oY Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S *Timestamps* 00:00:00 Huberman Lab Essentials; Muscle 00:02:02 Muscle & Nervous System 00:03:24 Strength & Aging, Henneman's Size Principle, Use Heavy Weights? 00:07:30 3 Stimuli, Muscle Strength vs Muscle Growth (Hypertrophy) 00:09:31 Tool: Resistance Training Protocol, Increase Muscle Strength 00:13:16 Tool: Advanced Resistance Training & Volume; Speed, Rest 00:16:17 Testing for Recovery, Heart Rate Variability, Grip Strength 00:19:54 Testing for Recovery, Carbon Dioxide Tolerance 00:22:51 Ice Bath Timing; NSAIDs & Exercise 00:24:06 Salt & Electrolytes; Creatine; Leucine #HubermanLab #Science #MuscleGrowth #Strength Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer https://www.youtube-nocookie.com/embed/jgaoLdS82vw 1669 2025-04-10T12:01:11.000Z 2026-10-22T19:21:29.716Z https://longevityharbor.com/en/watch/jki9zLQWHDc Video description on senolytics after 40: fisetin, quercetin and dasatinib claims https://i.ytimg.com/vi/jki9zLQWHDc/hqdefault.jpg The description says the video covers senolytics, compounds meant to selectively remove senescent cells that accumulate after age 40, and claims it explores 2025 and 2026 trials on fisetin, quercetin and dasatinib plus lifestyle factors such as fasting and high-intensity interval training. These are creator claims; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/jki9zLQWHDc 402 2026-03-06T11:15:10.000Z 2026-10-23T02:12:30.480Z https://longevityharbor.com/de/watch/jki9zLQWHDc Videobeschreibung zu Senolytika ab 40: Aussagen zu Fisetin, Quercetin und Dasatinib https://i.ytimg.com/vi/jki9zLQWHDc/hqdefault.jpg Laut Beschreibung behandelt das Video Senolytika, also Verbindungen, die seneszente Zellen gezielt entfernen sollen, welche sich nach dem 40. Lebensjahr ansammeln; zudem behauptet sie, 2025er- und 2026er-Studien zu Fisetin, Quercetin und Dasatinib sowie Lebensstilfaktoren wie Fasten und hochintensivem Intervalltraining zu beleuchten. Das sind Aussagen des Erstellers; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/jki9zLQWHDc 402 2026-03-06T11:15:10.000Z 2026-10-23T02:12:30.480Z https://longevityharbor.com/en/watch/jm1xsjBPwhw Read Your Epigenetic Test: 3 Evidence‑Backed Moves That Lower Biological Age https://i.ytimg.com/vi/jm1xsjBPwhw/hqdefault.jpg Check out this idea: Read Your Epigenetic Test: 3 Evidence‑Backed Moves That Lower Biological Age #YouTube #Content https://www.youtube-nocookie.com/embed/jm1xsjBPwhw 98 2026-07-18T14:02:08.000Z 2026-10-22T19:43:52.026Z https://longevityharbor.com/de/watch/jm1xsjBPwhw Read Your Epigenetic Test: 3 Evidence‑Backed Moves That Lower Biological Age https://i.ytimg.com/vi/jm1xsjBPwhw/hqdefault.jpg Check out this idea: Read Your Epigenetic Test: 3 Evidence‑Backed Moves That Lower Biological Age #YouTube #Content https://www.youtube-nocookie.com/embed/jm1xsjBPwhw 98 2026-07-18T14:02:08.000Z 2026-10-22T19:43:52.026Z https://longevityharbor.com/en/watch/k-MKrs_2354 Video description: claimed cellular aging reversal topics https://i.ytimg.com/vi/k-MKrs_2354/hqdefault.jpg The description says the video breaks down mechanisms claimed to drive biological age reversal, from epigenetic reprogramming to telomere preservation, clearing senescent cells and mitochondrial integrity. It presents no data, study details or results. https://www.youtube-nocookie.com/embed/k-MKrs_2354 452 2026-09-16T12:15:20.000Z 2026-10-22T22:10:26.890Z https://longevityharbor.com/de/watch/k-MKrs_2354 Videobeschreibung: behauptete Themen zur Umkehr zellulären Alterns https://i.ytimg.com/vi/k-MKrs_2354/hqdefault.jpg Laut Beschreibung erklärt das Video Mechanismen, die die Umkehr des biologischen Alters antreiben sollen – von epigenetischer Reprogrammierung über Telomererhalt bis zum Entfernen seneszenter Zellen und mitochondrialer Integrität. Daten, Studiendetails oder Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/k-MKrs_2354 452 2026-09-16T12:15:20.000Z 2026-10-22T22:10:26.890Z https://longevityharbor.com/en/watch/k0ggadqfjEQ Video description claims mouse lifespan, T-cell and senescence findings https://i.ytimg.com/vi/k0ggadqfjEQ/hqdefault.jpg The description claims mouse lifespan rose 6.6% via mitochondrial optimization, aged mice regained T-cell function with lipid nanoparticles, and senescence entry was found reversible; it also mentions a 14-clock, 174-disease framework. These are creator claims, not reviewed findings. https://www.youtube-nocookie.com/embed/k0ggadqfjEQ 2202 2025-12-24T16:52:29.000Z 2026-10-23T03:13:54.557Z https://longevityharbor.com/de/watch/k0ggadqfjEQ Videobeschreibung nennt Maus-Lebensspanne, T-Zell- und Seneszenz-Befunde https://i.ytimg.com/vi/k0ggadqfjEQ/hqdefault.jpg Die Beschreibung behauptet 6,6 % längere Lebensspanne bei Mäusen durch Mitochondrien-Optimierung, wiederhergestellte T-Zell-Funktion bei alten Mäusen mittels Lipid-Nanopartikeln und umkehrbaren Seneszenz-Eintritt; zudem einen Rahmen mit 14 Uhren und 174 Krankheiten. Das sind Angaben des Erstellers, keine geprüften Befunde. https://www.youtube-nocookie.com/embed/k0ggadqfjEQ 2202 2025-12-24T16:52:29.000Z 2026-10-23T03:13:54.557Z https://longevityharbor.com/en/watch/k4Y5vDJZRJ4 Gesunde Ernährung für ältere Menschen – ein Überblick https://i.ytimg.com/vi/k4Y5vDJZRJ4/hqdefault.jpg Mit höherem Alter lässt häufig der Appetit nach. Es ist oft schwierig, ältere Menschen zum Essen zu motivieren. Wir zeigen dir, - welche Portionsgrößen passen und wie häufig gegessen werden sollte- wie eine gesunde Mahlzeit ausschaut - wie du es schaffst alle notwendigen Lebensmittel in deinen Speiseplan einzubauen- wie du den Ernährungszustand messen und kontrollieren kannst. Natürlich bekommst du auch köstliche Rezeptideen und Tipps für den Alltag! 🥗 Rezeptebox: https://bit.ly/rezeptebox 00:00 Worum geht's? 00:18 Mahlzeitenfrequenz und Portionsgröße 01:07 Mahlzeitenzusammenstellung 01:58 Praktischer Teil: Die richtige Zusammenstellung 03:16 Appetitliches Anrichten 04:06 Ernährungszustand messen 05:14 Gemeinsam essen 05:39 Fragen zum Merken 06:27 Outtakes & Hoppalas www.medunigraz.at/ines https://www.youtube-nocookie.com/embed/k4Y5vDJZRJ4 433 2023-10-31T05:56:59.000Z 2026-10-22T18:43:10.912Z https://longevityharbor.com/de/watch/k4Y5vDJZRJ4 Gesunde Ernährung für ältere Menschen – ein Überblick https://i.ytimg.com/vi/k4Y5vDJZRJ4/hqdefault.jpg Mit höherem Alter lässt häufig der Appetit nach. Es ist oft schwierig, ältere Menschen zum Essen zu motivieren. Wir zeigen dir, - welche Portionsgrößen passen und wie häufig gegessen werden sollte- wie eine gesunde Mahlzeit ausschaut - wie du es schaffst alle notwendigen Lebensmittel in deinen Speiseplan einzubauen- wie du den Ernährungszustand messen und kontrollieren kannst. Natürlich bekommst du auch köstliche Rezeptideen und Tipps für den Alltag! 🥗 Rezeptebox: https://bit.ly/rezeptebox 00:00 Worum geht's? 00:18 Mahlzeitenfrequenz und Portionsgröße 01:07 Mahlzeitenzusammenstellung 01:58 Praktischer Teil: Die richtige Zusammenstellung 03:16 Appetitliches Anrichten 04:06 Ernährungszustand messen 05:14 Gemeinsam essen 05:39 Fragen zum Merken 06:27 Outtakes & Hoppalas www.medunigraz.at/ines https://www.youtube-nocookie.com/embed/k4Y5vDJZRJ4 433 2023-10-31T05:56:59.000Z 2026-10-22T18:43:10.912Z https://longevityharbor.com/en/watch/k4sjm_kr9TY Epigenetic Clocks Reveal Your True Biological Age – BUT, what you must know. https://i.ytimg.com/vi/k4sjm_kr9TY/hqdefault.jpg 👉 Take your health to another level: https://longevitylab.carrd.co/ Grab our recommended supplement: https://longevitylab.live Subscribe to the best FREE Longevity Newsletter: https://longevitylab.live Epigenetic Clocks Reveal Your True Biological Age – BUT, what you must know. Discover the fascinating world of epigenetic clocks and how they can reveal your true biological age in this eye-opening video. Understanding your biological age is crucial in longevity research, as it can provide valuable insights into your overall health and potential life expectancy. Join us to delve into why biological age matters and how epigenetic clocks are revolutionizing the way we approach aging. Learn what you must know about this cutting-edge technology and its implications for your well-being. Stay informed, stay youthful! https://www.youtube-nocookie.com/embed/k4sjm_kr9TY 171 2024-07-22T21:28:46.000Z 2026-10-22T17:43:35.271Z https://longevityharbor.com/de/watch/k4sjm_kr9TY Epigenetic Clocks Reveal Your True Biological Age – BUT, what you must know. https://i.ytimg.com/vi/k4sjm_kr9TY/hqdefault.jpg 👉 Take your health to another level: https://longevitylab.carrd.co/ Grab our recommended supplement: https://longevitylab.live Subscribe to the best FREE Longevity Newsletter: https://longevitylab.live Epigenetic Clocks Reveal Your True Biological Age – BUT, what you must know. Discover the fascinating world of epigenetic clocks and how they can reveal your true biological age in this eye-opening video. Understanding your biological age is crucial in longevity research, as it can provide valuable insights into your overall health and potential life expectancy. Join us to delve into why biological age matters and how epigenetic clocks are revolutionizing the way we approach aging. Learn what you must know about this cutting-edge technology and its implications for your well-being. Stay informed, stay youthful! https://www.youtube-nocookie.com/embed/k4sjm_kr9TY 171 2024-07-22T21:28:46.000Z 2026-10-22T17:43:35.271Z https://longevityharbor.com/en/watch/k8J-TFOApJc Part 1 - Intermittent Fasting & Disease Prevention: Clinical Research Explained https://i.ytimg.com/vi/k8J-TFOApJc/hqdefault.jpg Discover the latest clinical research on intermittent fasting and its potential to prevent diseases like cardiovascular conditions, diabetes, and neurological disorders. This video breaks down evidence-based findings on intermittent fasting and it's effects on weight loss, metabolic health, and long-term health outcomes. Part 2 is here https://www.youtube.com/watch?v=MzvmFyCaK5I&t=4s Subscribe to @trackhealthnews for more health and wellness summaries. #IntermittentFasting #DiseasePrevention #HealthResearch #FastingBenefits #ClinicalStudies #intermittentfastingbenefits https://www.youtube-nocookie.com/embed/k8J-TFOApJc 442 2025-03-12T04:00:41.000Z 2026-10-22T19:54:18.244Z https://longevityharbor.com/de/watch/k8J-TFOApJc Part 1 - Intermittent Fasting & Disease Prevention: Clinical Research Explained https://i.ytimg.com/vi/k8J-TFOApJc/hqdefault.jpg Discover the latest clinical research on intermittent fasting and its potential to prevent diseases like cardiovascular conditions, diabetes, and neurological disorders. This video breaks down evidence-based findings on intermittent fasting and it's effects on weight loss, metabolic health, and long-term health outcomes. Part 2 is here https://www.youtube.com/watch?v=MzvmFyCaK5I&t=4s Subscribe to @trackhealthnews for more health and wellness summaries. #IntermittentFasting #DiseasePrevention #HealthResearch #FastingBenefits #ClinicalStudies #intermittentfastingbenefits https://www.youtube-nocookie.com/embed/k8J-TFOApJc 442 2025-03-12T04:00:41.000Z 2026-10-22T19:54:18.244Z https://longevityharbor.com/en/watch/kBEytv78iRQ Cellular senescence and senolytics: what a video description claims about clearing 'zombie cells' https://i.ytimg.com/vi/kBEytv78iRQ/hqdefault.jpg The description says damaged cells can stop dividing and persist as senescent 'zombie cells' that release inflammatory signals harming nearby tissue. It says senolytics such as dasatinib, quercetin and navitoclax are being researched to remove these cells and restore tissue function. No human results are reported. https://www.youtube-nocookie.com/embed/kBEytv78iRQ 126 2026-10-17T18:30:08.000Z 2026-10-22T19:30:24.415Z https://longevityharbor.com/de/watch/kBEytv78iRQ Zelluläre Seneszenz und Senolytika: Was eine Videobeschreibung über das Entfernen von „Zombiezellen“ https://i.ytimg.com/vi/kBEytv78iRQ/hqdefault.jpg Die Beschreibung besagt, dass geschädigte Zellen aufhören können, sich zu teilen, und als seneszente „Zombiezellen“ fortbestehen, die entzündliche Signale abgeben und benachbartes Gewebe schädigen. Senolytika wie Dasatinib, Quercetin und Navitoclax werden laut Beschreibung erforscht, um diese Zellen zu entfernen und Gewebefunktion wiederherzustellen. Es werden keine Ergebnisse am Menschen berichtet. https://www.youtube-nocookie.com/embed/kBEytv78iRQ 126 2026-10-17T18:30:08.000Z 2026-10-22T19:30:24.415Z https://longevityharbor.com/en/watch/kBiUU6EJxCo Hongbing Zhang: Targeting Mechanistic Target of Rapamycin (mTOR) in Precision Medicine https://i.ytimg.com/vi/kBiUU6EJxCo/hqdefault.jpg Dr. Hongbing Zhang talked about the clinical applications of mTOR and rapamycin at the 5th Timepie Longevity Forum. Dr. Hongbing Zhang is a distinguished scientist with a notable academic and research career. He earned the Outstanding Dissertation Award from the Perelman School of Medicine at the University of Pennsylvania and completed his postdoctoral training at the National Institutes of Health (NIH) and Harvard Medical School, where he also served as a lecturer. Currently, he is a tenured professor at the Chinese Academy of Medical Sciences & Peking Union Medical College, a Distinguished Professor of the China Medical Board, a recipient of the National Science Fund for Distinguished Young Scholars, and a member of the State Key Laboratory of Common Mechanisms for Major Diseases. From 2014 to 2023, he has been recognized as one of China's Highly Cited Researchers and is currently ranked among the World's Top 2% Scientists. His research primarily focuses on the dysregulation of the mTOR signaling pathway and its role in the onset, diagnosis, and treatment of diseases such as cancer. His work encompasses a wide range of conditions from rare diseases, such as hereditary breast cancer and tuberous sclerosis complex, to common cancers like liver, pancreatic, and lung cancer. By simulating human gene mutations in animal models and constructing disease models, Dr. Zhang explores the mechanisms underlying tumor development and other diseases, aiming to identify effective therapeutic strategies. His research efforts have led to the advancement of clinical trials and provided a foundation for the translation of basic medical research into clinical practice, promoting precision medicine. Notably, his work has made significant strides in making tuberous sclerosis complex and similar conditions preventable and treatable, thus alleviating the lack of medical care and treatments for some patients. #mTOR #rapamycin Timepie Longevity Forum is China's premier longevity innovation summit, focuses on longevity popularization https://www.youtube-nocookie.com/embed/kBiUU6EJxCo 2420 2025-07-10T16:01:23.000Z 2026-10-22T19:54:22.431Z https://longevityharbor.com/de/watch/kBiUU6EJxCo Hongbing Zhang: Targeting Mechanistic Target of Rapamycin (mTOR) in Precision Medicine https://i.ytimg.com/vi/kBiUU6EJxCo/hqdefault.jpg Dr. Hongbing Zhang talked about the clinical applications of mTOR and rapamycin at the 5th Timepie Longevity Forum. Dr. Hongbing Zhang is a distinguished scientist with a notable academic and research career. He earned the Outstanding Dissertation Award from the Perelman School of Medicine at the University of Pennsylvania and completed his postdoctoral training at the National Institutes of Health (NIH) and Harvard Medical School, where he also served as a lecturer. Currently, he is a tenured professor at the Chinese Academy of Medical Sciences & Peking Union Medical College, a Distinguished Professor of the China Medical Board, a recipient of the National Science Fund for Distinguished Young Scholars, and a member of the State Key Laboratory of Common Mechanisms for Major Diseases. From 2014 to 2023, he has been recognized as one of China's Highly Cited Researchers and is currently ranked among the World's Top 2% Scientists. His research primarily focuses on the dysregulation of the mTOR signaling pathway and its role in the onset, diagnosis, and treatment of diseases such as cancer. His work encompasses a wide range of conditions from rare diseases, such as hereditary breast cancer and tuberous sclerosis complex, to common cancers like liver, pancreatic, and lung cancer. By simulating human gene mutations in animal models and constructing disease models, Dr. Zhang explores the mechanisms underlying tumor development and other diseases, aiming to identify effective therapeutic strategies. His research efforts have led to the advancement of clinical trials and provided a foundation for the translation of basic medical research into clinical practice, promoting precision medicine. Notably, his work has made significant strides in making tuberous sclerosis complex and similar conditions preventable and treatable, thus alleviating the lack of medical care and treatments for some patients. #mTOR #rapamycin Timepie Longevity Forum is China's premier longevity innovation summit, focuses on longevity popularization https://www.youtube-nocookie.com/embed/kBiUU6EJxCo 2420 2025-07-10T16:01:23.000Z 2026-10-22T19:54:22.431Z https://longevityharbor.com/en/watch/kDLZtGAbKe0 Intervallfasten im Praxistest: Wie schnell nimmt man ab? https://i.ytimg.com/vi/kDLZtGAbKe0/hqdefault.jpg In diesem Video erfährst du, wie viel Gewicht man in vier Wochen durch Intervallfasten verlieren kann. Um diese Frage zu beantworten, habe ich einen Praxistest mit einer Probandin durchgeführt. Ich habe sie vier Wochen lang begleitet und dabei die Veränderungen ihrer Energiezufuhr und ihres Körpergewichtes erfasst. YAZIO testen und gleichzeitig meine Arbeit ein wenig unterstützen: ➡️ https://tidd.ly/3Xtjr8g 📖 Quellen: [1] I. Elmadfa und C. Leitzmann, Ernährung des Menschen, 7. Aufl. (Ernährungswissenschaften, Ökotrophologie, Diätetik, Diätologie 8036). Stuttgart: Verlag Eugen Ulmer, 2023. [2] H.-K. Biesalski, S. C. Bischoff, M. Pirlich und A. Weimann, Hg. Ernährungsmedizin: Nach dem Curriculum Ernährungsmedizin der Bundesärztekammer, 5. Aufl. Stuttgart, New York: Georg Thieme Verlag, 2018. [3] M. Föller und G. I. Stangl, Hg. Ernährung - physiologische und praktische Grundlagen (Lehrbuch). Berlin, Germany: Springer Spektrum, 2021. [4] H.-K. Biesalski, P. Grimm und S. Nowitzki-Grimm, Taschenatlas Ernährung, 8. Aufl. Stuttgart: Thieme, 2020. [5] Interdisziplinäre Leitlinie der Qualität S3 zur „Prävention und Therapie der Adipositas“, Registernummer 050 - 001, Deutsche Adipositas-Gesellschaft e.V. (DAG), Apr. 2014. [6] C. A. Rynders, E. A. Thomas, A. Zaman, Z. Pan, V. A. Catenacci und E. L. Melanson, "Effectiveness of Intermittent Fasting and Time-Restricted Feeding Compared to Continuous Energy Restriction for Weight Loss," Nutrients, Early Access. doi: 10.3390/nu11102442. [7] K. K. Hoddy, K. L. Marlatt, H. Çetinkaya und E. Ravussin, "Intermittent Fasting and Metabolic Health: From Religious Fast to Time-Restricted Feeding," Obesity (Silver Spring, Md.), Jg. 28 Suppl 1, Suppl 1, S29-S37, 2020, doi: 10.1002/oby.22829. [8] R. E. Patterson und D. D. Sears, "Metabolic Effects of Intermittent Fasting," Annual review of nutrition, Early Access. doi: 10.1146/annurev-nutr-071816-064634. [9] S. Cienfuegos et al., "Effects of 4- and 6-h Time-Restricted Feeding on Weight and Cardiometabolic Health: A Randomized Cont https://www.youtube-nocookie.com/embed/kDLZtGAbKe0 534 2024-09-06T16:26:33.000Z 2026-10-22T19:32:41.998Z https://longevityharbor.com/de/watch/kDLZtGAbKe0 Intervallfasten im Praxistest: Wie schnell nimmt man ab? https://i.ytimg.com/vi/kDLZtGAbKe0/hqdefault.jpg In diesem Video erfährst du, wie viel Gewicht man in vier Wochen durch Intervallfasten verlieren kann. Um diese Frage zu beantworten, habe ich einen Praxistest mit einer Probandin durchgeführt. Ich habe sie vier Wochen lang begleitet und dabei die Veränderungen ihrer Energiezufuhr und ihres Körpergewichtes erfasst. YAZIO testen und gleichzeitig meine Arbeit ein wenig unterstützen: ➡️ https://tidd.ly/3Xtjr8g 📖 Quellen: [1] I. Elmadfa und C. Leitzmann, Ernährung des Menschen, 7. Aufl. (Ernährungswissenschaften, Ökotrophologie, Diätetik, Diätologie 8036). Stuttgart: Verlag Eugen Ulmer, 2023. [2] H.-K. Biesalski, S. C. Bischoff, M. Pirlich und A. Weimann, Hg. Ernährungsmedizin: Nach dem Curriculum Ernährungsmedizin der Bundesärztekammer, 5. Aufl. Stuttgart, New York: Georg Thieme Verlag, 2018. [3] M. Föller und G. I. Stangl, Hg. Ernährung - physiologische und praktische Grundlagen (Lehrbuch). Berlin, Germany: Springer Spektrum, 2021. [4] H.-K. Biesalski, P. Grimm und S. Nowitzki-Grimm, Taschenatlas Ernährung, 8. Aufl. Stuttgart: Thieme, 2020. [5] Interdisziplinäre Leitlinie der Qualität S3 zur „Prävention und Therapie der Adipositas“, Registernummer 050 - 001, Deutsche Adipositas-Gesellschaft e.V. (DAG), Apr. 2014. [6] C. A. Rynders, E. A. Thomas, A. Zaman, Z. Pan, V. A. Catenacci und E. L. Melanson, "Effectiveness of Intermittent Fasting and Time-Restricted Feeding Compared to Continuous Energy Restriction for Weight Loss," Nutrients, Early Access. doi: 10.3390/nu11102442. [7] K. K. Hoddy, K. L. Marlatt, H. Çetinkaya und E. Ravussin, "Intermittent Fasting and Metabolic Health: From Religious Fast to Time-Restricted Feeding," Obesity (Silver Spring, Md.), Jg. 28 Suppl 1, Suppl 1, S29-S37, 2020, doi: 10.1002/oby.22829. [8] R. E. Patterson und D. D. Sears, "Metabolic Effects of Intermittent Fasting," Annual review of nutrition, Early Access. doi: 10.1146/annurev-nutr-071816-064634. [9] S. Cienfuegos et al., "Effects of 4- and 6-h Time-Restricted Feeding on Weight and Cardiometabolic Health: A Randomized Cont https://www.youtube-nocookie.com/embed/kDLZtGAbKe0 534 2024-09-06T16:26:33.000Z 2026-10-22T19:32:41.998Z https://longevityharbor.com/en/watch/kE-ep1kBziQ #10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — living longer, healthier & turning back the clock https://i.ytimg.com/vi/kE-ep1kBziQ/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Original release date: 8/20/2018 Matt is someone who is deeply interested in understanding the biology of aging. Why do we age? What happens to us as we age? What are the things we can do to slow the aging process? How can we delay or prevent the onset of age-related diseases? These are all questions that Matt thinks deeply about, and explores these questions with his research at the University of Washington. He is currently investigating many of these questions through the Dog Aging Project and the compound rapamycin—the only known pharmacological agent to extend lifespan all the way from yeast to mammals—across a billion years of evolution. We talk about cancer, heart disease, Alzheimer’s disease, healthspan, lifespan, and what we can do to provide longer, healthier lives for both people and dogs. We discuss: -Matt’s early years and his aha moment on aging [4:00]; -Studying dogs [6:30]; -Dogs, rapamycin, and its effects on lifespan and healthspan [15:30]; -An unexpected finding in presumably healthy dogs [36:00]; -Rapamycin in cancer treatment [50:00]; -Why isn’t there a rapamycin trial for Alzheimer’s disease (AD)? [1:01:30]; -If Matt could do a definitive study on life extension in dogs, with resources not being a concern, what does that experiment look like? [1:16:00]; and -More. Show notes page: https://peterattiamd.com/mattkaeberlein/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 10 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. The practice applies nutritional biochemistry, exercise physiology, sleep physiology, techniques to increase distress tolerance, lipidology, pharmacology, and https://www.youtube-nocookie.com/embed/kE-ep1kBziQ 5574 2019-12-23T03:50:59.000Z 2026-10-22T17:43:41.819Z https://longevityharbor.com/de/watch/kE-ep1kBziQ #10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — living longer, healthier & turning back the clock https://i.ytimg.com/vi/kE-ep1kBziQ/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Original release date: 8/20/2018 Matt is someone who is deeply interested in understanding the biology of aging. Why do we age? What happens to us as we age? What are the things we can do to slow the aging process? How can we delay or prevent the onset of age-related diseases? These are all questions that Matt thinks deeply about, and explores these questions with his research at the University of Washington. He is currently investigating many of these questions through the Dog Aging Project and the compound rapamycin—the only known pharmacological agent to extend lifespan all the way from yeast to mammals—across a billion years of evolution. We talk about cancer, heart disease, Alzheimer’s disease, healthspan, lifespan, and what we can do to provide longer, healthier lives for both people and dogs. We discuss: -Matt’s early years and his aha moment on aging [4:00]; -Studying dogs [6:30]; -Dogs, rapamycin, and its effects on lifespan and healthspan [15:30]; -An unexpected finding in presumably healthy dogs [36:00]; -Rapamycin in cancer treatment [50:00]; -Why isn’t there a rapamycin trial for Alzheimer’s disease (AD)? [1:01:30]; -If Matt could do a definitive study on life extension in dogs, with resources not being a concern, what does that experiment look like? [1:16:00]; and -More. Show notes page: https://peterattiamd.com/mattkaeberlein/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 10 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. The practice applies nutritional biochemistry, exercise physiology, sleep physiology, techniques to increase distress tolerance, lipidology, pharmacology, and https://www.youtube-nocookie.com/embed/kE-ep1kBziQ 5574 2019-12-23T03:50:59.000Z 2026-10-22T17:43:41.819Z https://longevityharbor.com/en/watch/kEVBfxDk2n0 This Study Says Intermittent Fasting May Be Bad for Your Heart | EP 36 CLIP https://i.ytimg.com/vi/kEVBfxDk2n0/hqdefault.jpg FULL EPISODE: https://youtu.be/59SFzLEy6Jg Subscribe to our channel: https://www.youtube.com/@optispan In this episode, we discuss three findings that have made the rounds in the geroscience and healthspan spaces in recent months. They relate to three universally-relevant topics: pregnancy, exercise, and diet. The first study suggested that women who have been pregnant at least once age faster than women who had never been pregnant, controlling for social, environmental, and genetic variation and measuring aging rate via six epigenetic clocks. The second study found a connection between workout timing and cardiovascular disease, microvascular disease, and all-cause mortality risk in adults with obesity. Evening workouts appeared to lead to the greatest morbidity and mortality benefits. The third study, which researchers presented at a recent American Heart Association meeting, demonstrated a positive relationship between time-restricted eating—that is, eating all daily meals in a short time window rather than throughout the day—and risk of dying from heart disease. It's been an interesting time for geroscience-related findings. Matt and Nick chat about the three studies, discussing their potential limitations, possible mechanisms underlying the observed longevity effects, and further work that would provide greater depth to our understanding of healthspan and longevity. DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and gu https://www.youtube-nocookie.com/embed/kEVBfxDk2n0 1017 2024-08-20T14:00:50.000Z 2026-10-22T19:54:18.329Z https://longevityharbor.com/de/watch/kEVBfxDk2n0 This Study Says Intermittent Fasting May Be Bad for Your Heart | EP 36 CLIP https://i.ytimg.com/vi/kEVBfxDk2n0/hqdefault.jpg FULL EPISODE: https://youtu.be/59SFzLEy6Jg Subscribe to our channel: https://www.youtube.com/@optispan In this episode, we discuss three findings that have made the rounds in the geroscience and healthspan spaces in recent months. They relate to three universally-relevant topics: pregnancy, exercise, and diet. The first study suggested that women who have been pregnant at least once age faster than women who had never been pregnant, controlling for social, environmental, and genetic variation and measuring aging rate via six epigenetic clocks. The second study found a connection between workout timing and cardiovascular disease, microvascular disease, and all-cause mortality risk in adults with obesity. Evening workouts appeared to lead to the greatest morbidity and mortality benefits. The third study, which researchers presented at a recent American Heart Association meeting, demonstrated a positive relationship between time-restricted eating—that is, eating all daily meals in a short time window rather than throughout the day—and risk of dying from heart disease. It's been an interesting time for geroscience-related findings. Matt and Nick chat about the three studies, discussing their potential limitations, possible mechanisms underlying the observed longevity effects, and further work that would provide greater depth to our understanding of healthspan and longevity. DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and gu https://www.youtube-nocookie.com/embed/kEVBfxDk2n0 1017 2024-08-20T14:00:50.000Z 2026-10-22T19:54:18.329Z https://longevityharbor.com/en/watch/kEkXnlIBHyo Rapamycin and Immune Rejuvenation: How a Longevity Drug Resets Aging Immunity https://i.ytimg.com/vi/kEkXnlIBHyo/hqdefault.jpg Most people think aging weakens the immune system, but science shows it becomes misaligned instead. This video examines how rapamycin may help reset the immune balance and restore youthful function. Aging doesn’t just reduce immunity; it can overactivate responses in the wrong places, causing inflammation and autoimmunity while failing to protect against infections. This imbalance explains why older adults often respond poorly to vaccines and experience chronic health issues. Rapamycin, a compound originally used in organ transplants and cancer therapy, has shown remarkable potential to fine-tune the immune system rather than suppress it. Short-term treatment in animal and human studies appears to reduce chronic inflammation, allowing the immune system to function more like a younger one. These effects are not limited to immunity; similar rejuvenation has been observed in organs like the heart, brain, and liver. In this clip, Dr. Matt Kaeberlein and Peter Attia break down how rapamycin works at the cellular level, activating autophagy and restoring proper mTOR signaling. You’ll learn why even transient dosing can have long-lasting benefits for immune health, vaccine response, and overall resilience during aging. Whether you are a longevity enthusiast, biohacker, or health-conscious individual, this video offers actionable insights into one of the most promising compounds in aging research. Watch the full podcast here: https://www.youtube.com/watch?v=O67pvKxio10&t=350s Learn more about Rapamycin as a supplement here: https://www.rapashop.net #rapamycin #immunerejuvenation #longevity #antiaging #mtor #autophagy #agingresearch #healthspan #lifespan #geroscience #immunesystem #Biohacking #humanperformance https://www.youtube-nocookie.com/embed/kEkXnlIBHyo 127 2025-10-01T21:00:06.000Z 2026-10-22T19:54:22.239Z https://longevityharbor.com/de/watch/kEkXnlIBHyo Rapamycin and Immune Rejuvenation: How a Longevity Drug Resets Aging Immunity https://i.ytimg.com/vi/kEkXnlIBHyo/hqdefault.jpg Most people think aging weakens the immune system, but science shows it becomes misaligned instead. This video examines how rapamycin may help reset the immune balance and restore youthful function. Aging doesn’t just reduce immunity; it can overactivate responses in the wrong places, causing inflammation and autoimmunity while failing to protect against infections. This imbalance explains why older adults often respond poorly to vaccines and experience chronic health issues. Rapamycin, a compound originally used in organ transplants and cancer therapy, has shown remarkable potential to fine-tune the immune system rather than suppress it. Short-term treatment in animal and human studies appears to reduce chronic inflammation, allowing the immune system to function more like a younger one. These effects are not limited to immunity; similar rejuvenation has been observed in organs like the heart, brain, and liver. In this clip, Dr. Matt Kaeberlein and Peter Attia break down how rapamycin works at the cellular level, activating autophagy and restoring proper mTOR signaling. You’ll learn why even transient dosing can have long-lasting benefits for immune health, vaccine response, and overall resilience during aging. Whether you are a longevity enthusiast, biohacker, or health-conscious individual, this video offers actionable insights into one of the most promising compounds in aging research. Watch the full podcast here: https://www.youtube.com/watch?v=O67pvKxio10&t=350s Learn more about Rapamycin as a supplement here: https://www.rapashop.net #rapamycin #immunerejuvenation #longevity #antiaging #mtor #autophagy #agingresearch #healthspan #lifespan #geroscience #immunesystem #Biohacking #humanperformance https://www.youtube-nocookie.com/embed/kEkXnlIBHyo 127 2025-10-01T21:00:06.000Z 2026-10-22T19:54:22.239Z https://longevityharbor.com/en/watch/kFfSNXLWc24 Video description: five exercises for people over 60 https://i.ytimg.com/vi/kFfSNXLWc24/hqdefault.jpg The description says five basic exercises may help people over 60 improve strength, balance, mobility and general fitness, described as a simple routine for healthy aging and more independence. https://www.youtube-nocookie.com/embed/kFfSNXLWc24 674 2026-06-15T21:00:29.000Z 2026-10-22T23:57:48.704Z https://longevityharbor.com/de/watch/kFfSNXLWc24 Videobeschreibung: fünf Übungen für Menschen über 60 https://i.ytimg.com/vi/kFfSNXLWc24/hqdefault.jpg Laut Beschreibung können fünf grundlegende Übungen Menschen über 60 helfen, Kraft, Gleichgewicht, Mobilität und allgemeine Fitness zu verbessern – als einfache Routine für gesundes Altern und mehr Unabhängigkeit. https://www.youtube-nocookie.com/embed/kFfSNXLWc24 674 2026-06-15T21:00:29.000Z 2026-10-22T23:57:48.704Z https://longevityharbor.com/en/watch/kFlhhp5VpMg 40 g vs 20 g of casein before bed: overnight muscle protein building in 48 older men https://i.ytimg.com/vi/kFlhhp5VpMg/hqdefault.jpg In one study of 48 healthy men averaging 72 years, 40 g of casein before sleep increased overnight muscle protein building compared with a protein-free drink, while 20 g showed no clear difference. Only the rate of muscle protein synthesis was measured, not muscle size or strength. https://www.youtube-nocookie.com/embed/kFlhhp5VpMg 94 2026-10-22T09:00:34.000Z 2026-10-22T19:47:06.486Z https://longevityharbor.com/de/watch/kFlhhp5VpMg 40 g vs. 20 g Casein vor dem Schlafen: nächtlicher Muskelproteinaufbau bei 48 älteren Männern https://i.ytimg.com/vi/kFlhhp5VpMg/hqdefault.jpg In einer Studie mit 48 gesunden Männern im Durchschnittsalter von 72 Jahren steigerte 40 g Casein vor dem Schlafen den nächtlichen Muskelproteinaufbau im Vergleich zu einem proteinfreien Getränk; 20 g zeigten keinen klaren Unterschied. Gemessen wurde nur die Rate der Muskelproteinsynthese, nicht Muskelgröße oder Kraft. https://www.youtube-nocookie.com/embed/kFlhhp5VpMg 94 2026-10-22T09:00:34.000Z 2026-10-22T19:47:06.486Z https://longevityharbor.com/en/watch/kTdRZysA9dg Kalorienrestriktion & Fasten 🥦⏳ https://i.ytimg.com/vi/kTdRZysA9dg/hqdefault.jpg Weniger essen, länger leben? 🤔 Die Wahrheit über Kalorienrestriktion & Fasten!🧬“ Weniger essen und trotzdem gesünder altern 🧓✨, länger leben? 🧠⏱️ In diesem Short erfährst du komprimiert, wie Kalorienrestriktion 🥗 und intermittierendes Fasten 🕐 👉 deine Zellen schützen 🔬 👉 Alterungsprozesse verlangsamen 🧓🐢 👉 und sogar Entzündungen im Körper reduzieren 🔥➡️❄️ können. Wissenschaftlich erklärt – kompakt, spannend und verständlich! 📚⚡ #Fasten ⏳ #Kalorienrestriktion 🥗 #Langlebigkeit 💪 #Gesundheit ❤️ #AntiAging 👶🧓 #Longevity 🌱 #WissenschaftKurzErklärt 🔍 ⚠️ Haftungsausschluss / Disclaimer Die auf diesem YouTube-Kanal bereitgestellten Inhalte dienen ausschließlich der neutralen Information und allgemeinen Weiterbildung zu medizinischen, gesundheitsbezogenen und wissenschaftlichen Themen. Sie stellen keine medizinische Beratung, Diagnose oder Therapieempfehlung dar und ersetzen nicht den Besuch bei einer Ärztin oder einem Arzt. 👉 Bei gesundheitlichen Beschwerden oder Fragen zur Diagnose und Therapie wende dich bitte immer an eine medizinische Fachkraft. Ich übernehme keine Haftung für Schäden oder Unannehmlichkeiten, die durch den Gebrauch oder Missbrauch der hier bereitgestellten Informationen entstehen. 🌐 Externe Links: Dieser Kanal kann Verlinkungen zu externen Websites oder Quellen enthalten. Für deren Inhalte sind ausschließlich die jeweiligen Betreiber verantwortlich. Ich habe keinerlei Einfluss auf die Inhalte und übernehme keine Gewähr für deren Richtigkeit, Aktualität oder Rechtmäßigkeit. https://www.youtube-nocookie.com/embed/kTdRZysA9dg 121 2025-06-27T14:00:11.000Z 2026-10-22T17:43:37.676Z https://longevityharbor.com/de/watch/kTdRZysA9dg Kalorienrestriktion & Fasten 🥦⏳ https://i.ytimg.com/vi/kTdRZysA9dg/hqdefault.jpg Weniger essen, länger leben? 🤔 Die Wahrheit über Kalorienrestriktion & Fasten!🧬“ Weniger essen und trotzdem gesünder altern 🧓✨, länger leben? 🧠⏱️ In diesem Short erfährst du komprimiert, wie Kalorienrestriktion 🥗 und intermittierendes Fasten 🕐 👉 deine Zellen schützen 🔬 👉 Alterungsprozesse verlangsamen 🧓🐢 👉 und sogar Entzündungen im Körper reduzieren 🔥➡️❄️ können. Wissenschaftlich erklärt – kompakt, spannend und verständlich! 📚⚡ #Fasten ⏳ #Kalorienrestriktion 🥗 #Langlebigkeit 💪 #Gesundheit ❤️ #AntiAging 👶🧓 #Longevity 🌱 #WissenschaftKurzErklärt 🔍 ⚠️ Haftungsausschluss / Disclaimer Die auf diesem YouTube-Kanal bereitgestellten Inhalte dienen ausschließlich der neutralen Information und allgemeinen Weiterbildung zu medizinischen, gesundheitsbezogenen und wissenschaftlichen Themen. Sie stellen keine medizinische Beratung, Diagnose oder Therapieempfehlung dar und ersetzen nicht den Besuch bei einer Ärztin oder einem Arzt. 👉 Bei gesundheitlichen Beschwerden oder Fragen zur Diagnose und Therapie wende dich bitte immer an eine medizinische Fachkraft. Ich übernehme keine Haftung für Schäden oder Unannehmlichkeiten, die durch den Gebrauch oder Missbrauch der hier bereitgestellten Informationen entstehen. 🌐 Externe Links: Dieser Kanal kann Verlinkungen zu externen Websites oder Quellen enthalten. Für deren Inhalte sind ausschließlich die jeweiligen Betreiber verantwortlich. Ich habe keinerlei Einfluss auf die Inhalte und übernehme keine Gewähr für deren Richtigkeit, Aktualität oder Rechtmäßigkeit. https://www.youtube-nocookie.com/embed/kTdRZysA9dg 121 2025-06-27T14:00:11.000Z 2026-10-22T17:43:37.676Z https://longevityharbor.com/en/watch/kkodky-g3ro Water Fasting vs. Fasting-Mimicking Diet (FMD): Which is SAFER & BETTER for Autophagy & Longevity? https://i.ytimg.com/vi/kkodky-g3ro/hqdefault.jpg Fasting is the hottest topic in longevity right now, and the buzzword is Autophagy—your body's incredible cellular cleanup process. But do you have to starve yourself for days just drinking water to get the benefits? 🤔 In this video, we break down the ultimate longevity showdown: Traditional Water Fasting vs. The Fasting-Mimicking Diet (FMD) developed by Dr. Valter Longo. 💧 Water Fasting (The Classic) We cover why going zero-calorie is the most direct and potent way to trigger deep autophagy, like hitting a cellular "reset button." But we don't shy away from the major downsides: it's mentally brutal, carries significant physical risks (headaches, dizziness, muscle loss), and requires serious caution and supervision. 🍎 The Fasting-Mimicking Diet (FMD) Discover the "fasting with training wheels." For five days, the FMD uses a specific, low-calorie, low-protein, high-fat diet to trick your body into thinking it's fasting. You still get a massive boost in autophagy and stem cell regeneration, but it’s dramatically safer, easier to stick to, and protects precious muscle mass. The Bottom Line If you're looking for a sustainable, science-backed way to unlock the rewards of longevity fasting without the high risk and intense suffering, is FMD the answer for you? In This Video, You Will Learn: What Autophagy is and why it is crucial for cellular health and longevity. The intense pros and significant cons of an extended water fast. How Dr. Valter Longo's FMD works to "trick" your nutrient-sensing pathways. Which fasting approach is safer, more sustainable, and better for the vast majority of people. Want more simple breakdowns of complex health science? 👍 Like this video and SUBSCRIBE for more longevity tips! 🔔 Hit the notification bell so you don't miss our next video! #FastingMimickingDiet #WaterFasting #Autophagy #Longevity #DrValterLongo #IntermittentFasting #HealthHacks #FMD #CellularHealth #Biohacking https://www.youtube-nocookie.com/embed/kkodky-g3ro 143 2025-11-16T05:26:47.000Z 2026-10-22T19:54:16.999Z https://longevityharbor.com/de/watch/kkodky-g3ro Water Fasting vs. Fasting-Mimicking Diet (FMD): Which is SAFER & BETTER for Autophagy & Longevity? https://i.ytimg.com/vi/kkodky-g3ro/hqdefault.jpg Fasting is the hottest topic in longevity right now, and the buzzword is Autophagy—your body's incredible cellular cleanup process. But do you have to starve yourself for days just drinking water to get the benefits? 🤔 In this video, we break down the ultimate longevity showdown: Traditional Water Fasting vs. The Fasting-Mimicking Diet (FMD) developed by Dr. Valter Longo. 💧 Water Fasting (The Classic) We cover why going zero-calorie is the most direct and potent way to trigger deep autophagy, like hitting a cellular "reset button." But we don't shy away from the major downsides: it's mentally brutal, carries significant physical risks (headaches, dizziness, muscle loss), and requires serious caution and supervision. 🍎 The Fasting-Mimicking Diet (FMD) Discover the "fasting with training wheels." For five days, the FMD uses a specific, low-calorie, low-protein, high-fat diet to trick your body into thinking it's fasting. You still get a massive boost in autophagy and stem cell regeneration, but it’s dramatically safer, easier to stick to, and protects precious muscle mass. The Bottom Line If you're looking for a sustainable, science-backed way to unlock the rewards of longevity fasting without the high risk and intense suffering, is FMD the answer for you? In This Video, You Will Learn: What Autophagy is and why it is crucial for cellular health and longevity. The intense pros and significant cons of an extended water fast. How Dr. Valter Longo's FMD works to "trick" your nutrient-sensing pathways. Which fasting approach is safer, more sustainable, and better for the vast majority of people. Want more simple breakdowns of complex health science? 👍 Like this video and SUBSCRIBE for more longevity tips! 🔔 Hit the notification bell so you don't miss our next video! #FastingMimickingDiet #WaterFasting #Autophagy #Longevity #DrValterLongo #IntermittentFasting #HealthHacks #FMD #CellularHealth #Biohacking https://www.youtube-nocookie.com/embed/kkodky-g3ro 143 2025-11-16T05:26:47.000Z 2026-10-22T19:54:16.999Z https://longevityharbor.com/en/watch/knv8NkuBTZE Doctors discuss biological age beyond years lived https://i.ytimg.com/vi/knv8NkuBTZE/hqdefault.jpg In this video description, two doctors say biological ageing can be assessed beyond chronological age, using medical parameters plus sleep, exercise tolerance, muscle mass and quality of life. https://www.youtube-nocookie.com/embed/knv8NkuBTZE 98 2026-09-17T05:28:40.000Z 2026-10-22T22:10:02.379Z https://longevityharbor.com/de/watch/knv8NkuBTZE Ärzte besprechen biologisches Alter jenseits der Lebensjahre https://i.ytimg.com/vi/knv8NkuBTZE/hqdefault.jpg In dieser Videobeschreibung sagen zwei Ärzte, biologisches Altern lasse sich jenseits des chronologischen Alters beurteilen – anhand medizinischer Parameter sowie Schlaf, Belastungstoleranz, Muskelmasse und Lebensqualität. https://www.youtube-nocookie.com/embed/knv8NkuBTZE 98 2026-09-17T05:28:40.000Z 2026-10-22T22:10:02.379Z https://longevityharbor.com/en/watch/knvX_yULDTo Video describes a Nature Aging study on 14% calorie restriction and plasma proteins https://i.ytimg.com/vi/knvX_yULDTo/hqdefault.jpg The description says two years of about 14% calorie restriction in healthy adults shifted the blood proteome toward a more youthful profile and lowered estimated biological age mainly in fat tissue, with little effect on heart, muscle and kidney and higher age signals in pancreas and intestine. https://www.youtube-nocookie.com/embed/knvX_yULDTo 561 2026-04-15T12:53:59.000Z 2026-10-23T01:35:02.549Z https://longevityharbor.com/de/watch/knvX_yULDTo Video beschreibt eine Nature-Aging-Studie zu 14 % Kalorienrestriktion und Plasmaproteinen https://i.ytimg.com/vi/knvX_yULDTo/hqdefault.jpg Laut Beschreibung verschob eine zweijährige Kalorienrestriktion von etwa 14 % bei gesunden Erwachsenen das Blutproteom in ein jüngeres Profil und senkte das geschätzte biologische Alter vor allem im Fettgewebe, kaum bei Herz, Muskel und Niere, während Pankreas und Darm höhere Alterssignale zeigten. https://www.youtube-nocookie.com/embed/knvX_yULDTo 561 2026-04-15T12:53:59.000Z 2026-10-23T01:35:02.549Z https://longevityharbor.com/en/watch/kuxVfl_gKfE Kritchevsky conversation: function, walking speed and measuring anti-aging therapies https://i.ytimg.com/vi/kuxVfl_gKfE/hqdefault.jpg In this described episode, Stephen Kritchevsky discusses mobility, metabolism and resilience in aging, including why walking speed predicts health, cognition and survival, muscle mass versus muscle quality, and what it would take to measure a therapy that slows aging. https://www.youtube-nocookie.com/embed/kuxVfl_gKfE 2685 2026-04-01T15:42:49.000Z 2026-10-23T01:49:30.068Z https://longevityharbor.com/de/watch/kuxVfl_gKfE Kritchevsky-Gespräch: Funktion, Gehgeschwindigkeit und Messung von Anti-Aging-Therapien https://i.ytimg.com/vi/kuxVfl_gKfE/hqdefault.jpg In dieser beschriebenen Episode spricht Stephen Kritchevsky über Mobilität, Stoffwechsel und Resilienz im Altern, darunter warum die Gehgeschwindigkeit Gesundheit, Kognition und Überleben vorhersagt, Muskelmasse versus Muskelqualität und was nötig wäre, um eine das Altern verlangsamende Therapie zu messen. https://www.youtube-nocookie.com/embed/kuxVfl_gKfE 2685 2026-04-01T15:42:49.000Z 2026-10-23T01:49:30.068Z https://longevityharbor.com/en/watch/kwLnS1o7L2o Astaxanthin vs NMN astaxanthin nmn antiaging nad resultsmayvary https://i.ytimg.com/vi/kwLnS1o7L2o/hqdefault.jpg Astaxanthin vs NMN astaxanthin nmn antiaging nad resultsmayvary https://www.youtube-nocookie.com/embed/kwLnS1o7L2o 139 2026-06-08T05:56:50.000Z 2026-10-22T19:32:37.558Z https://longevityharbor.com/de/watch/kwLnS1o7L2o Astaxanthin vs NMN astaxanthin nmn antiaging nad resultsmayvary https://i.ytimg.com/vi/kwLnS1o7L2o/hqdefault.jpg Astaxanthin vs NMN astaxanthin nmn antiaging nad resultsmayvary https://www.youtube-nocookie.com/embed/kwLnS1o7L2o 139 2026-06-08T05:56:50.000Z 2026-10-22T19:32:37.558Z https://longevityharbor.com/en/watch/l0mFPoYNHOE Judith Campisi - Senolytics for Healthy Aging https://i.ytimg.com/vi/l0mFPoYNHOE/hqdefault.jpg Judith Campisi is an American biochemist and cell biologist. She is a professor of biogerontology at the Buck Institute for Research on Aging. She is also a member of the SENS Research Foundation Advisory Board and an adviser at the Lifeboat Foundation. She is co-editor in chief of the Aging Journal, together with Mikhail Blagosklonny and David Sinclair, and founder of the pharmaceutical company Unity Biotechnology. She is listed in Who's Who in Gerontology. She is widely known for her research on how senescent cells influence aging and cancer — in particular the senescence-associated secretory phenotype (SASP). Judy Campisi, The Buck Institute for Research on Aging, presenting at Undoing Aging 2019 #senolytics #biotech #anti-aging #antiaging #undoingaging #longevity Many thanks for watching! Consider supporting SciFuture by: a) Subscribing to the SciFuture YouTube channel: http://youtube.com/subscription_center?add_user=TheRationalFuture b) Donating - Bitcoin: 1BxusYmpynJsH4i8681aBuw9ZTxbKoUi22 - Etherium: 0xd46a6e88c4fe179d04464caf42626d0c9cab1c6b - Patreon: https://www.patreon.com/scifuture c) Sharing the media SciFuture creates: http://scifuture.org Kind regards, Adam Ford - Science, Technology & the Future https://www.youtube-nocookie.com/embed/l0mFPoYNHOE 1845 2019-07-31T10:37:12.000Z 2026-10-23T02:56:02.615Z https://longevityharbor.com/de/watch/l0mFPoYNHOE Judith Campisi - Senolytics for Healthy Aging https://i.ytimg.com/vi/l0mFPoYNHOE/hqdefault.jpg Judith Campisi is an American biochemist and cell biologist. She is a professor of biogerontology at the Buck Institute for Research on Aging. She is also a member of the SENS Research Foundation Advisory Board and an adviser at the Lifeboat Foundation. She is co-editor in chief of the Aging Journal, together with Mikhail Blagosklonny and David Sinclair, and founder of the pharmaceutical company Unity Biotechnology. She is listed in Who's Who in Gerontology. She is widely known for her research on how senescent cells influence aging and cancer — in particular the senescence-associated secretory phenotype (SASP). Judy Campisi, The Buck Institute for Research on Aging, presenting at Undoing Aging 2019 #senolytics #biotech #anti-aging #antiaging #undoingaging #longevity Many thanks for watching! Consider supporting SciFuture by: a) Subscribing to the SciFuture YouTube channel: http://youtube.com/subscription_center?add_user=TheRationalFuture b) Donating - Bitcoin: 1BxusYmpynJsH4i8681aBuw9ZTxbKoUi22 - Etherium: 0xd46a6e88c4fe179d04464caf42626d0c9cab1c6b - Patreon: https://www.patreon.com/scifuture c) Sharing the media SciFuture creates: http://scifuture.org Kind regards, Adam Ford - Science, Technology & the Future https://www.youtube-nocookie.com/embed/l0mFPoYNHOE 1845 2019-07-31T10:37:12.000Z 2026-10-23T02:56:02.615Z https://longevityharbor.com/en/watch/l6vxXoDF6Hs Toxic Ties - How Negative Relationships Age Your Body https://i.ytimg.com/vi/l6vxXoDF6Hs/hqdefault.jpg Emerging research in geroscience reveals that negative social ties—frequently characterized as hasslers or stressful relationships—can measurably accelerate biological aging at a cellular level. Studies utilizing DNA methylation epigenetic clocks, such as DunedinPACE and GrimAge2, demonstrate that each additional high-conflict or emotionally draining person in a close social network is associated with roughly nine additional months of biological wear and tear and a 1.5 percent faster pace of aging per year. These toxic interactions act as chronic stressors that trigger physiological strain, dysregulating the hypothalamic-pituitary-adrenal axis and resulting in elevated systemic inflammation, increased allostatic load, higher rates of depression and anxiety, and a greater prevalence of chronic health conditions. Notably, the biological impact varies by relationship type: difficult family ties show the strongest connection to accelerated aging due to persistent obligations and difficulty in establishing distance, whereas non-family negative ties primarily contribute to cumulative long-term wear. Strain in marriage exhibits a less pronounced effect on aging speed, suggesting that marital companionship and support may partially buffer relational stress. Beyond immediate interpersonal dynamics, these findings align with broader concepts regarding the social hallmarks of aging, demonstrating how social adversity and relational quality directly get under the skin to influence long-term healthspan and biological longevity. https://www.youtube-nocookie.com/embed/l6vxXoDF6Hs 866 2026-10-10T21:53:21.000Z 2026-10-22T19:54:20.437Z https://longevityharbor.com/de/watch/l6vxXoDF6Hs Toxic Ties - How Negative Relationships Age Your Body https://i.ytimg.com/vi/l6vxXoDF6Hs/hqdefault.jpg Emerging research in geroscience reveals that negative social ties—frequently characterized as hasslers or stressful relationships—can measurably accelerate biological aging at a cellular level. Studies utilizing DNA methylation epigenetic clocks, such as DunedinPACE and GrimAge2, demonstrate that each additional high-conflict or emotionally draining person in a close social network is associated with roughly nine additional months of biological wear and tear and a 1.5 percent faster pace of aging per year. These toxic interactions act as chronic stressors that trigger physiological strain, dysregulating the hypothalamic-pituitary-adrenal axis and resulting in elevated systemic inflammation, increased allostatic load, higher rates of depression and anxiety, and a greater prevalence of chronic health conditions. Notably, the biological impact varies by relationship type: difficult family ties show the strongest connection to accelerated aging due to persistent obligations and difficulty in establishing distance, whereas non-family negative ties primarily contribute to cumulative long-term wear. Strain in marriage exhibits a less pronounced effect on aging speed, suggesting that marital companionship and support may partially buffer relational stress. Beyond immediate interpersonal dynamics, these findings align with broader concepts regarding the social hallmarks of aging, demonstrating how social adversity and relational quality directly get under the skin to influence long-term healthspan and biological longevity. https://www.youtube-nocookie.com/embed/l6vxXoDF6Hs 866 2026-10-10T21:53:21.000Z 2026-10-22T19:54:20.437Z https://longevityharbor.com/en/watch/l7OBw-yz9ho Dr. Newman's description: shifting healthy aging from disease treatment to healthspan https://i.ytimg.com/vi/l7OBw-yz9ho/hqdefault.jpg In this video description, Dr. John C. Newman is said to redefine healthy aging by shifting the focus from treating disease to optimizing healthspan. The session also reportedly explores ways to build regional and national geroscience initiatives for long-term impact. https://www.youtube-nocookie.com/embed/l7OBw-yz9ho 1786 2026-01-13T05:30:22.000Z 2026-10-23T02:54:36.015Z https://longevityharbor.com/de/watch/l7OBw-yz9ho Dr. Newmans Beschreibung: gesundes Altern von Krankheitsbehandlung auf Healthspan verlagern https://i.ytimg.com/vi/l7OBw-yz9ho/hqdefault.jpg In dieser Videobeschreibung wird Dr. John C. Newman so beschrieben, dass er gesundes Altern neu definiert, indem er den Fokus von der Krankheitsbehandlung auf die Optimierung der Healthspan verlagert. Die Sitzung erkundet laut Beschreibung außerdem Wege zu regionalen und nationalen Geroscience-Initiativen für langfristige Wirkung. https://www.youtube-nocookie.com/embed/l7OBw-yz9ho 1786 2026-01-13T05:30:22.000Z 2026-10-23T02:54:36.015Z https://longevityharbor.com/en/watch/l8OVSFmtuBA "Shocking Discoveries: Can Exercise Truly Reverse Aging?" https://i.ytimg.com/vi/l8OVSFmtuBA/hqdefault.jpg Are you curious about the latest research on aging and exercise? Dive into this eye-opening video where we explore the question, "Can Exercise Truly Reverse Aging?" New research shows a reduction in age-related fat, revealing promising findings. Discover the secrets, myths, and truths about reversing aging through exercise. Don't miss out on this essential information that could change the way you approach fitness and aging. Subscribe now for more groundbreaking insights! https://www.youtube-nocookie.com/embed/l8OVSFmtuBA 99 2024-04-17T23:30:08.000Z 2026-10-22T18:54:06.035Z https://longevityharbor.com/de/watch/l8OVSFmtuBA "Shocking Discoveries: Can Exercise Truly Reverse Aging?" https://i.ytimg.com/vi/l8OVSFmtuBA/hqdefault.jpg Are you curious about the latest research on aging and exercise? Dive into this eye-opening video where we explore the question, "Can Exercise Truly Reverse Aging?" New research shows a reduction in age-related fat, revealing promising findings. Discover the secrets, myths, and truths about reversing aging through exercise. Don't miss out on this essential information that could change the way you approach fitness and aging. Subscribe now for more groundbreaking insights! https://www.youtube-nocookie.com/embed/l8OVSFmtuBA 99 2024-04-17T23:30:08.000Z 2026-10-22T18:54:06.035Z https://longevityharbor.com/en/watch/l9fxPhJm_1E Fix Your Diet & Lifestyle To Heal Your Skin: Reverse Acne, Aging & Wrinkles | Dr. Anthony Youn https://i.ytimg.com/vi/l9fxPhJm_1E/hqdefault.jpg We know there are key lifestyle practices that can help us feel good and look good. But with all the latest skin care products and trends, it can be hard to sort through what is actually beneficial, worth investing in, and safe to use as part of our effort to look younger. Today’s guest, America’s Holistic Plastic Surgeon, helps us navigate through what's worth implementing in our busy lives. Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Anthony Youn, a board-certified plastic surgeon. Dr. Youn guides us through lifestyle factors that prematurely age us, key ingredients to look for in quality skincare products, and his 2-minute skincare routine that can help us look five years younger. Dr. Youn also gives us his hot takes on collagen, botox, microneedling, and fillers and the research that supports his suggestions. If you are curious about the latest in skincare and beauty, this episode is a must-listen. Dr. Anthony Youn is a nationally recognized, board-certified plastic surgeon. He is known as America’s holistic plastic surgeon and is the author of the best-selling books The Age Fix and Playing God. Dr. Youn also hosts the popular podcast The Holistic Plastic Surgery Show. His new book, Younger for Life, is a complete holistic guide to turning back the clock using the process of Autojuvenation. In this episode, Dhru and Dr. Youn dive into: -What is prematurely aging you -How sugar impacts our skin and body -The importance of natural skin care products and investigating ingredients -Nutrient deprivation in the soil and our diets -Is it worth it to take collagen supplements -The impact of inflammation -The impact of chronic stress on aging our body -Free radical damage and its impact on aging -Healthy sun exposure, avoiding sun damage, and sunscreen recommendations -Botox and considerations before use -Skincare routines for men versus women -The 2 minute look five years younger skincare routine -Skincare interventions that have the best returns -The benefits of microneedling -The tr https://www.youtube-nocookie.com/embed/l9fxPhJm_1E 7843 2023-12-28T14:00:29.000Z 2026-10-22T19:43:45.215Z https://longevityharbor.com/de/watch/l9fxPhJm_1E Fix Your Diet & Lifestyle To Heal Your Skin: Reverse Acne, Aging & Wrinkles | Dr. Anthony Youn https://i.ytimg.com/vi/l9fxPhJm_1E/hqdefault.jpg We know there are key lifestyle practices that can help us feel good and look good. But with all the latest skin care products and trends, it can be hard to sort through what is actually beneficial, worth investing in, and safe to use as part of our effort to look younger. Today’s guest, America’s Holistic Plastic Surgeon, helps us navigate through what's worth implementing in our busy lives. Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Anthony Youn, a board-certified plastic surgeon. Dr. Youn guides us through lifestyle factors that prematurely age us, key ingredients to look for in quality skincare products, and his 2-minute skincare routine that can help us look five years younger. Dr. Youn also gives us his hot takes on collagen, botox, microneedling, and fillers and the research that supports his suggestions. If you are curious about the latest in skincare and beauty, this episode is a must-listen. Dr. Anthony Youn is a nationally recognized, board-certified plastic surgeon. He is known as America’s holistic plastic surgeon and is the author of the best-selling books The Age Fix and Playing God. Dr. Youn also hosts the popular podcast The Holistic Plastic Surgery Show. His new book, Younger for Life, is a complete holistic guide to turning back the clock using the process of Autojuvenation. In this episode, Dhru and Dr. Youn dive into: -What is prematurely aging you -How sugar impacts our skin and body -The importance of natural skin care products and investigating ingredients -Nutrient deprivation in the soil and our diets -Is it worth it to take collagen supplements -The impact of inflammation -The impact of chronic stress on aging our body -Free radical damage and its impact on aging -Healthy sun exposure, avoiding sun damage, and sunscreen recommendations -Botox and considerations before use -Skincare routines for men versus women -The 2 minute look five years younger skincare routine -Skincare interventions that have the best returns -The benefits of microneedling -The tr https://www.youtube-nocookie.com/embed/l9fxPhJm_1E 7843 2023-12-28T14:00:29.000Z 2026-10-22T19:43:45.215Z https://longevityharbor.com/en/watch/l9l_DvVLcyI Book chapter video on experimental aging science https://i.ytimg.com/vi/l9l_DvVLcyI/hqdefault.jpg The creator says this final Chapter 4 video covers themes of experimental science in aging biology that is speeding translational gerontology from bench to clinic. https://www.youtube-nocookie.com/embed/l9l_DvVLcyI 1007 2026-07-05T17:10:09.000Z 2026-10-22T23:39:26.692Z https://longevityharbor.com/de/watch/l9l_DvVLcyI Buchkapitel-Video zur experimentellen Alternsforschung https://i.ytimg.com/vi/l9l_DvVLcyI/hqdefault.jpg Der Ersteller sagt, dieses letzte Kapitel-4-Video behandele Themen der experimentellen Wissenschaft in der Alternsbiologie, die die translationale Gerontologie vom Labor in die Klinik beschleunigt. https://www.youtube-nocookie.com/embed/l9l_DvVLcyI 1007 2026-07-05T17:10:09.000Z 2026-10-22T23:39:26.692Z https://longevityharbor.com/en/watch/lAaL1PyEP9k Expert video description questions NAD infusions, unregulated peptides and stem cells https://i.ytimg.com/vi/lAaL1PyEP9k/hqdefault.jpg In this video description, geriatrician and longevity researcher Professor Andrea Maier tells host Dr. Natalie Hutchins that NAD infusions, peptides and stem cells are marketed as biohacks but may do more harm than good; she calls NAD infusions physiologically dirty and flags risks of unregulated peptides. https://www.youtube-nocookie.com/embed/lAaL1PyEP9k 2640 2026-02-17T22:00:49.000Z 2026-10-23T02:28:20.187Z https://longevityharbor.com/de/watch/lAaL1PyEP9k Experten-Videobeschreibung hinterfragt NAD-Infusionen, unregulierte Peptide und Stammzellen https://i.ytimg.com/vi/lAaL1PyEP9k/hqdefault.jpg In dieser Videobeschreibung sagt Geriaterin und Longevity-Forscherin Professorin Andrea Maier gegenüber Gastgeberin Dr. Natalie Hutchins, NAD-Infusionen, Peptide und Stammzellen würden als Biohacks vermarktet, könnten aber mehr schaden als nützen; sie nennt NAD-Infusionen physiologisch unsauber und warnt vor Risiken unregulierter Peptide. https://www.youtube-nocookie.com/embed/lAaL1PyEP9k 2640 2026-02-17T22:00:49.000Z 2026-10-23T02:28:20.187Z https://longevityharbor.com/en/watch/lFWA0uvUqtU Dr. Irina Conboy discusses aging clocks and epigenetic noise as an aging biomarker https://i.ytimg.com/vi/lFWA0uvUqtU/hqdefault.jpg In this Journal Club description, Dr. Irina Conboy of UC Berkeley is said to discuss misalignment around aging clocks and to walk through her latest work on epigenetic noise itself as a biomarker for aging. https://www.youtube-nocookie.com/embed/lFWA0uvUqtU 4872 2025-12-30T21:35:38.000Z 2026-10-23T03:04:05.408Z https://longevityharbor.com/de/watch/lFWA0uvUqtU Dr. Irina Conboy diskutiert Altersuhren und epigenetisches Rauschen als Alters-Biomarker https://i.ytimg.com/vi/lFWA0uvUqtU/hqdefault.jpg In dieser Journal-Club-Beschreibung wird berichtet, dass Dr. Irina Conboy von der UC Berkeley Missverständnisse rund um Altersuhren erörtert und ihre neueste Arbeit zu epigenetischem Rauschen selbst als Biomarker des Alterns vorstellt. https://www.youtube-nocookie.com/embed/lFWA0uvUqtU 4872 2025-12-30T21:35:38.000Z 2026-10-23T03:04:05.408Z https://longevityharbor.com/en/watch/lI0Gj1DXY6Q Morgan Levine: Using epigenetic clocks to determine biological age https://i.ytimg.com/vi/lI0Gj1DXY6Q/hqdefault.jpg We are all used to feeling younger than our years and occasionally older than our birth date would suggest.  In effect, we have two ages - chronological and biological. Chronological age simply states the number of years that we have been alive, whereas biological age is a measure of how well our bodies are performing, in relation to the rest of the population.  So how is it determined?  LLAMA host Peter Bowes delved into the science with Elysium Health, which has developed Index, a DNA test that tracks how fast we have been aging, based on our epigenome, which regulates the way genes work.  In this episode, Peter meets Dr. Morgan Levine, an assistant professor of pathology at Yale School of Medicine and an advisor to Elysium Health. They discuss the background to Index, its use of epigenetic clocks to put a number to our biological age, as well as the test's accuracy and implications for healthy living. Recorded: April 21, 2021 | Read a transcript (http://www.llamapodcast.com/morgan-levine/#TRANSCRIPT) and show notes at the LLAMA podcast website. (http://www.llamapodcast.com/morgan-levine)   Topics covered in this interview include: • Defining biological age and chronological age.  • Age as a risk factor for death and disease • Having an older parent and developing an interest in aging  • A lack of consensus over what exactly is meant by aging. • How much of aging can be defined as damage to the body, at a cellular level, as we grow older? • How do we measure biological age?   • Genes, genomes and the epigenome. • Developing systems that determine biological age based on epigenetic clocks. • Exploring the Index epigenetic, at-home saliva test, to determine biological age.     • Privacy concerns related to sharing personal medical information.   • Revealing Peter's biological versus chronological age. What does it mean?  • Interpreting the test results and taking action based on the findings. • Does the test reveal information specific to potential medical condition https://www.youtube-nocookie.com/embed/lI0Gj1DXY6Q 2158 2023-11-03T16:00:05.000Z 2026-10-22T19:21:27.648Z https://longevityharbor.com/de/watch/lI0Gj1DXY6Q Morgan Levine: Using epigenetic clocks to determine biological age https://i.ytimg.com/vi/lI0Gj1DXY6Q/hqdefault.jpg We are all used to feeling younger than our years and occasionally older than our birth date would suggest.  In effect, we have two ages - chronological and biological. Chronological age simply states the number of years that we have been alive, whereas biological age is a measure of how well our bodies are performing, in relation to the rest of the population.  So how is it determined?  LLAMA host Peter Bowes delved into the science with Elysium Health, which has developed Index, a DNA test that tracks how fast we have been aging, based on our epigenome, which regulates the way genes work.  In this episode, Peter meets Dr. Morgan Levine, an assistant professor of pathology at Yale School of Medicine and an advisor to Elysium Health. They discuss the background to Index, its use of epigenetic clocks to put a number to our biological age, as well as the test's accuracy and implications for healthy living. Recorded: April 21, 2021 | Read a transcript (http://www.llamapodcast.com/morgan-levine/#TRANSCRIPT) and show notes at the LLAMA podcast website. (http://www.llamapodcast.com/morgan-levine)   Topics covered in this interview include: • Defining biological age and chronological age.  • Age as a risk factor for death and disease • Having an older parent and developing an interest in aging  • A lack of consensus over what exactly is meant by aging. • How much of aging can be defined as damage to the body, at a cellular level, as we grow older? • How do we measure biological age?   • Genes, genomes and the epigenome. • Developing systems that determine biological age based on epigenetic clocks. • Exploring the Index epigenetic, at-home saliva test, to determine biological age.     • Privacy concerns related to sharing personal medical information.   • Revealing Peter's biological versus chronological age. What does it mean?  • Interpreting the test results and taking action based on the findings. • Does the test reveal information specific to potential medical condition https://www.youtube-nocookie.com/embed/lI0Gj1DXY6Q 2158 2023-11-03T16:00:05.000Z 2026-10-22T19:21:27.648Z https://longevityharbor.com/en/watch/lOMw26vA8ic Collaboration webinar: Cellular Senescence and Senolytics in Aging and Diseases https://i.ytimg.com/vi/lOMw26vA8ic/hqdefault.jpg Join us for a BioTalk webinar on cellular senescence, a hallmark of aging where cells permanently exit the cell cycle due to damage and stress. Cellular senescence, a hallmark of aging, involves the stable exit from the cell cycle in response to cellular damage and stress. Senescent cells (SnCs) often develop a pathogenic senescence-associated secretory phenotype (SASP) that promotes secondary senescence and disrupts tissue homeostasis, impairing tissue repair and regeneration. Transgenic mouse models with the capability for genetic ablation of SnCs have demonstrated their crucial role in driving aging and related diseases. Consequently, senotherapeutics have been developed to either pharmacologically eliminate SnCs (senolytics) or suppress the SASP and other senescence markers (senomorphics). Extensive preclinical studies and initial clinical trials have shown the potential benefits of senotherapeutics, leading to multiple ongoing clinical trials. In conclusion, targeting cellular senescence presents a promising therapeutic strategy for slowing aging and treating age-related diseases. This webinar is made in collaboration with GenoBioTx https://www.youtube-nocookie.com/embed/lOMw26vA8ic 3278 2024-09-25T21:53:48.000Z 2026-10-22T18:43:13.510Z https://longevityharbor.com/de/watch/lOMw26vA8ic Collaboration webinar: Cellular Senescence and Senolytics in Aging and Diseases https://i.ytimg.com/vi/lOMw26vA8ic/hqdefault.jpg Join us for a BioTalk webinar on cellular senescence, a hallmark of aging where cells permanently exit the cell cycle due to damage and stress. Cellular senescence, a hallmark of aging, involves the stable exit from the cell cycle in response to cellular damage and stress. Senescent cells (SnCs) often develop a pathogenic senescence-associated secretory phenotype (SASP) that promotes secondary senescence and disrupts tissue homeostasis, impairing tissue repair and regeneration. Transgenic mouse models with the capability for genetic ablation of SnCs have demonstrated their crucial role in driving aging and related diseases. Consequently, senotherapeutics have been developed to either pharmacologically eliminate SnCs (senolytics) or suppress the SASP and other senescence markers (senomorphics). Extensive preclinical studies and initial clinical trials have shown the potential benefits of senotherapeutics, leading to multiple ongoing clinical trials. In conclusion, targeting cellular senescence presents a promising therapeutic strategy for slowing aging and treating age-related diseases. This webinar is made in collaboration with GenoBioTx https://www.youtube-nocookie.com/embed/lOMw26vA8ic 3278 2024-09-25T21:53:48.000Z 2026-10-22T18:43:13.510Z https://longevityharbor.com/en/watch/lPImNtEyXF4 Die richtige Bewegung, um gesund zu altern - FAZ Gesundheit https://i.ytimg.com/vi/lPImNtEyXF4/hqdefault.jpg Unser Körper beginnt viel früher zu altern, als es uns bewusst und vielen vermutlich auch recht ist. Mit der richtigen Bewegung kann man den Alterungsprozess aber zumindest verlangsamen. Dazu sollte es übrigens auch gehören, die Sinne zu trainieren und nicht nur die Muskeln. Warum - das erklärt Dr. Malte Rubach, Ernährungswissenschaftler und Buchautor, im Podcast. https://www.youtube-nocookie.com/embed/lPImNtEyXF4 1284 2020-06-28T03:01:23.000Z 2026-10-22T17:43:36.022Z https://longevityharbor.com/de/watch/lPImNtEyXF4 Die richtige Bewegung, um gesund zu altern - FAZ Gesundheit https://i.ytimg.com/vi/lPImNtEyXF4/hqdefault.jpg Unser Körper beginnt viel früher zu altern, als es uns bewusst und vielen vermutlich auch recht ist. Mit der richtigen Bewegung kann man den Alterungsprozess aber zumindest verlangsamen. Dazu sollte es übrigens auch gehören, die Sinne zu trainieren und nicht nur die Muskeln. Warum - das erklärt Dr. Malte Rubach, Ernährungswissenschaftler und Buchautor, im Podcast. https://www.youtube-nocookie.com/embed/lPImNtEyXF4 1284 2020-06-28T03:01:23.000Z 2026-10-22T17:43:36.022Z https://longevityharbor.com/en/watch/lRXIH3LxyuE Ozempic in nematodes: mTOR-linked neuronal effects on ageing https://i.ytimg.com/vi/lRXIH3LxyuE/hqdefault.jpg A conference description says a PhD student's poster examined Ozempic in the nematode C. elegans and linked its effects to neuronal inhibition of mTOR, while stressing that findings must be investigated further before translation to humans. https://www.youtube-nocookie.com/embed/lRXIH3LxyuE 494 2026-08-26T07:26:33.000Z 2026-10-22T22:42:24.358Z https://longevityharbor.com/de/watch/lRXIH3LxyuE Ozempic bei Fadenwürmern: mTOR-gebundene neuronale Effekte aufs Altern https://i.ytimg.com/vi/lRXIH3LxyuE/hqdefault.jpg Eine Konferenzbeschreibung berichtet, ein Doktorand habe in einem Poster Ozempic am Fadenwurm C. elegans untersucht und die Effekte mit neuronaler Hemmung von mTOR verknüpft; zugleich wird betont, dass weitere Forschung nötig ist, bevor Ergebnisse auf Menschen übertragen werden. https://www.youtube-nocookie.com/embed/lRXIH3LxyuE 494 2026-08-26T07:26:33.000Z 2026-10-22T22:42:24.358Z https://longevityharbor.com/en/watch/lSdJ_U-1faM Video description: sleep cycles, non-REM stages and REM sleep https://i.ytimg.com/vi/lSdJ_U-1faM/hqdefault.jpg The description says the video explains a typical 90-minute sleep cycle, non-REM stages 1 to 3 and REM sleep, and how disrupted cycles may affect memory, mood and immune function. https://www.youtube-nocookie.com/embed/lSdJ_U-1faM 108 2026-05-31T12:59:38.000Z 2026-10-23T00:16:36.570Z https://longevityharbor.com/de/watch/lSdJ_U-1faM Videobeschreibung: Schlafzyklen, Non-REM-Phasen und REM-Schlaf https://i.ytimg.com/vi/lSdJ_U-1faM/hqdefault.jpg Laut Beschreibung erklärt das Video einen typischen 90-Minuten-Schlafzyklus, die Non-REM-Phasen 1 bis 3 und den REM-Schlaf sowie mögliche Folgen gestörter Zyklen für Gedächtnis, Stimmung und Immunfunktion. https://www.youtube-nocookie.com/embed/lSdJ_U-1faM 108 2026-05-31T12:59:38.000Z 2026-10-23T00:16:36.570Z https://longevityharbor.com/en/watch/lY2p7s3KYOU The NAD+ Breakthrough: Has Science Finally Cured Aging? (NMN vs NR) https://i.ytimg.com/vi/lY2p7s3KYOU/hqdefault.jpg Is aging just a disease that can be reversed? we investigate the ultimate frontier of human biology: The Science of Longevity and NAD+. Pioneered by researchers like Harvard’s Dr. David Sinclair, the "Information Theory of Aging" suggests that our cells don't lose their genetic code; they just lose the ability to read it. The key to rebooting the system lies in Sirtuins (Longevity Genes) and their vital fuel source: NAD+. What you’ll learn: • The Epigenetic Piano: The real biological reason we get wrinkles and chronic disease. • The NAD+ Crisis: Why your cellular energy drops by 50% by the time you reach age 50. • The Thieves (CD38 & PARPs): How "Zombie Cells" and DNA damage drain your youth. • NMN vs. NR: The science behind NAD+ precursors and how they enter the cell. • The Synergy Protocol: Why taking NMN without activating AMPK (via fasting or exercise) is a waste of money. • TMG & Resveratrol: The exact stack used by longevity experts to maximize DNA repair safely. Stop accepting the physical decline. Learn the BioTruth of the biological clock. 🔍 SOURCES & RESEARCH Check the first pinned comment for Dr. David Sinclair’s research, clinical trials on NMN/NR, and our complete "Longevity Dosage Protocol." ⚠️ DISCLAIMER This video is for educational purposes. NAD+ precursors are powerful metabolic molecules. If you have active cancer or a history of tumors, consult your oncologist before taking NAD+ boosters, as rapidly growing cells also utilize NAD+ for energy. BioTruth Lab, NAD+ supplements, NMN vs NR, Dr David Sinclair NMN, How to reverse aging, Information theory of aging, Sirtuins longevity genes, Epigenetics and aging, CD38 inhibitors, Senescent zombie cells, TMG supplement benefits, Resveratrol with NMN, Slc12a8 transporter, Fasting for longevity, Anti-aging biohacking, Boost NAD+ naturally, Mitochondrial health. https://www.youtube-nocookie.com/embed/lY2p7s3KYOU 383 2026-03-03T00:28:29.000Z 2026-10-22T19:04:43.064Z https://longevityharbor.com/de/watch/lY2p7s3KYOU The NAD+ Breakthrough: Has Science Finally Cured Aging? (NMN vs NR) https://i.ytimg.com/vi/lY2p7s3KYOU/hqdefault.jpg Is aging just a disease that can be reversed? we investigate the ultimate frontier of human biology: The Science of Longevity and NAD+. Pioneered by researchers like Harvard’s Dr. David Sinclair, the "Information Theory of Aging" suggests that our cells don't lose their genetic code; they just lose the ability to read it. The key to rebooting the system lies in Sirtuins (Longevity Genes) and their vital fuel source: NAD+. What you’ll learn: • The Epigenetic Piano: The real biological reason we get wrinkles and chronic disease. • The NAD+ Crisis: Why your cellular energy drops by 50% by the time you reach age 50. • The Thieves (CD38 & PARPs): How "Zombie Cells" and DNA damage drain your youth. • NMN vs. NR: The science behind NAD+ precursors and how they enter the cell. • The Synergy Protocol: Why taking NMN without activating AMPK (via fasting or exercise) is a waste of money. • TMG & Resveratrol: The exact stack used by longevity experts to maximize DNA repair safely. Stop accepting the physical decline. Learn the BioTruth of the biological clock. 🔍 SOURCES & RESEARCH Check the first pinned comment for Dr. David Sinclair’s research, clinical trials on NMN/NR, and our complete "Longevity Dosage Protocol." ⚠️ DISCLAIMER This video is for educational purposes. NAD+ precursors are powerful metabolic molecules. If you have active cancer or a history of tumors, consult your oncologist before taking NAD+ boosters, as rapidly growing cells also utilize NAD+ for energy. BioTruth Lab, NAD+ supplements, NMN vs NR, Dr David Sinclair NMN, How to reverse aging, Information theory of aging, Sirtuins longevity genes, Epigenetics and aging, CD38 inhibitors, Senescent zombie cells, TMG supplement benefits, Resveratrol with NMN, Slc12a8 transporter, Fasting for longevity, Anti-aging biohacking, Boost NAD+ naturally, Mitochondrial health. https://www.youtube-nocookie.com/embed/lY2p7s3KYOU 383 2026-03-03T00:28:29.000Z 2026-10-22T19:04:43.064Z https://longevityharbor.com/en/watch/lZRh97IR8Ec Longevity, mTOR, & Muscle https://i.ytimg.com/vi/lZRh97IR8Ec/hqdefault.jpg Longevity isn’t just about living longer—it’s about moving better, healing stronger, and staying resilient. Here’s what you need to know about mTOR: 🔥 mTOR gets a bad rap but it’s essential. Some longevity experts focus only on suppressing it. I say: Goldilocks it—not too much, not too little. 🦴 I needed to turn ON mTOR to heal my bone. That meant shifting into a growth phase—protein, peptides, strength training. ⚠️ The fear? mTOR could fuel cancer cell growth. But current research doesn’t support it causing cancer—only possibly accelerating what's already there. 🚨 Suppressing growth too much is a bigger threat. Why? Because sarcopenia, osteopenia, and immune decline are real killers in aging. 💪 Muscle is your metabolic currency. As Gabrielle Lyon says—muscle is the organ of longevity. Without it, your risk of falls, infections, and frailty skyrockets. The key? Strategic cycling of mTOR activation through protein, strength training, and timing so you build strength without overstimulating growth pathways. 👉 Aging isn’t optional. How you age is. #LongevityScience #mTOR #MuscleIsMedicine #HealthyAging https://www.youtube-nocookie.com/embed/lZRh97IR8Ec 141 2025-09-28T13:00:47.000Z 2026-10-22T19:32:35.531Z https://longevityharbor.com/de/watch/lZRh97IR8Ec Longevity, mTOR, & Muscle https://i.ytimg.com/vi/lZRh97IR8Ec/hqdefault.jpg Longevity isn’t just about living longer—it’s about moving better, healing stronger, and staying resilient. Here’s what you need to know about mTOR: 🔥 mTOR gets a bad rap but it’s essential. Some longevity experts focus only on suppressing it. I say: Goldilocks it—not too much, not too little. 🦴 I needed to turn ON mTOR to heal my bone. That meant shifting into a growth phase—protein, peptides, strength training. ⚠️ The fear? mTOR could fuel cancer cell growth. But current research doesn’t support it causing cancer—only possibly accelerating what's already there. 🚨 Suppressing growth too much is a bigger threat. Why? Because sarcopenia, osteopenia, and immune decline are real killers in aging. 💪 Muscle is your metabolic currency. As Gabrielle Lyon says—muscle is the organ of longevity. Without it, your risk of falls, infections, and frailty skyrockets. The key? Strategic cycling of mTOR activation through protein, strength training, and timing so you build strength without overstimulating growth pathways. 👉 Aging isn’t optional. How you age is. #LongevityScience #mTOR #MuscleIsMedicine #HealthyAging https://www.youtube-nocookie.com/embed/lZRh97IR8Ec 141 2025-09-28T13:00:47.000Z 2026-10-22T19:32:35.531Z https://longevityharbor.com/en/watch/la0yeKTmDQE NAD vs NMN? Which oral supplement should you choose for healthy aging and longevity? #nmn #nad https://i.ytimg.com/vi/la0yeKTmDQE/hqdefault.jpg NAD vs NMN? Which oral supplement should you choose for healthy aging and longevity? #nmn #nad #antiaging #tiktokshopstockup #over40 https://www.youtube-nocookie.com/embed/la0yeKTmDQE 132 2026-09-06T21:08:11.000Z 2026-10-22T17:43:42.550Z https://longevityharbor.com/de/watch/la0yeKTmDQE NAD vs NMN? Which oral supplement should you choose for healthy aging and longevity? #nmn #nad https://i.ytimg.com/vi/la0yeKTmDQE/hqdefault.jpg NAD vs NMN? Which oral supplement should you choose for healthy aging and longevity? #nmn #nad #antiaging #tiktokshopstockup #over40 https://www.youtube-nocookie.com/embed/la0yeKTmDQE 132 2026-09-06T21:08:11.000Z 2026-10-22T17:43:42.550Z https://longevityharbor.com/en/watch/lf1GCNgGKKI Physician's NMN and NAD video description: routine claims, not tested outcomes https://i.ytimg.com/vi/lf1GCNgGKKI/hqdefault.jpg The description says NAD production falls with age and that NMN is a usable precursor, then outlines a suggested routine. It reports no study, data or measured outcomes. https://www.youtube-nocookie.com/embed/lf1GCNgGKKI 111 2026-09-27T00:25:41.000Z 2026-10-22T21:43:57.720Z https://longevityharbor.com/de/watch/lf1GCNgGKKI Arzt-Beschreibung zu NMN und NAD: Routinenangaben, keine geprüften Ergebnisse https://i.ytimg.com/vi/lf1GCNgGKKI/hqdefault.jpg Die Beschreibung sagt, die NAD-Produktion sinke mit dem Alter, und NMN sei eine nutzbare Vorstufe; dann skizziert sie eine vorgeschlagene Routine. Sie nennt keine Studie, Daten oder gemessene Ergebnisse. https://www.youtube-nocookie.com/embed/lf1GCNgGKKI 111 2026-09-27T00:25:41.000Z 2026-10-22T21:43:57.720Z https://longevityharbor.com/en/watch/li2fhq-tI8A Rapamycin and aging: what the described human trials reportedly found https://i.ytimg.com/vi/li2fhq-tI8A/hqdefault.jpg The description says the video ranks rapamycin evidence from mouse lifespan studies to first human longevity trials, noting mouse evidence is strong while the human picture is more complicated. https://www.youtube-nocookie.com/embed/li2fhq-tI8A 925 2026-07-16T02:32:36.000Z 2026-10-22T23:30:39.712Z https://longevityharbor.com/de/watch/li2fhq-tI8A Rapamycin und Altern: was die beschriebenen Humanstudien laut Beschreibung fanden https://i.ytimg.com/vi/li2fhq-tI8A/hqdefault.jpg Laut Beschreibung ordnet das Video die Rapamycin-Evidenz von Maus-Lebensspannenstudien bis zu ersten Human-Langlebigkeitsstudien ein: Mausevidenz sei stark, das menschliche Bild komplizierter. https://www.youtube-nocookie.com/embed/li2fhq-tI8A 925 2026-07-16T02:32:36.000Z 2026-10-22T23:30:39.712Z https://longevityharbor.com/en/watch/ls0eClWD7E8 Geroscience - Extending Healthy Lifespan: A Healthspan Primer for Friends and Family https://i.ytimg.com/vi/ls0eClWD7E8/hqdefault.jpg I created this short video as a friendly introduction for friends and family who may not be familiar with the field. It gives an overview of why we age and why supporting research on modifying the biology of aging is so important. It's about making sure we all enjoy long, healthy, and vibrant lives. That's something we all deserve. Yours truly, David Barzilai MD PhD... the "Agingdoc" --- I share a variety of content circulating on X (formerly Twitter) to highlight ongoing discussions. Please note, this is for informational purposes only and not a reflection of data quality—I share both good and bad to encourage open dialogue. You can follow along here: https://twitter.com/agingdoc1 In addition to that, I'm a physician specializing in lifestyle medicine and evidence-based longevity. For more information, you can visit my LinkedIn profile: https://www.linkedin.com/in/agingdoc https://www.youtube-nocookie.com/embed/ls0eClWD7E8 586 2024-10-03T20:43:02.000Z 2026-10-22T19:54:20.161Z https://longevityharbor.com/de/watch/ls0eClWD7E8 Geroscience - Extending Healthy Lifespan: A Healthspan Primer for Friends and Family https://i.ytimg.com/vi/ls0eClWD7E8/hqdefault.jpg I created this short video as a friendly introduction for friends and family who may not be familiar with the field. It gives an overview of why we age and why supporting research on modifying the biology of aging is so important. It's about making sure we all enjoy long, healthy, and vibrant lives. That's something we all deserve. Yours truly, David Barzilai MD PhD... the "Agingdoc" --- I share a variety of content circulating on X (formerly Twitter) to highlight ongoing discussions. Please note, this is for informational purposes only and not a reflection of data quality—I share both good and bad to encourage open dialogue. You can follow along here: https://twitter.com/agingdoc1 In addition to that, I'm a physician specializing in lifestyle medicine and evidence-based longevity. For more information, you can visit my LinkedIn profile: https://www.linkedin.com/in/agingdoc https://www.youtube-nocookie.com/embed/ls0eClWD7E8 586 2024-10-03T20:43:02.000Z 2026-10-22T19:54:20.161Z https://longevityharbor.com/en/watch/lt8Z0fNukBw Video description on NMN, NAD and NR: claims, trial findings and open questions https://i.ytimg.com/vi/lt8Z0fNukBw/hqdefault.jpg The description says the video covers the discovery of SIR2 and NAD in longevity research, the correlation between NAD levels and aging, hype around NMN and NR supplements, David Sinclair's advocacy for NMN, Interventions Testing Program findings on NR, doubts about NAD declining with age, NR and long COVID, and whether TMG explains benefits. https://www.youtube-nocookie.com/embed/lt8Z0fNukBw 538 2025-12-27T16:57:13.000Z 2026-10-23T03:07:30.005Z https://longevityharbor.com/de/watch/lt8Z0fNukBw Videobeschreibung zu NMN, NAD und NR: Aussagen, Studienergebnisse und offene Fragen https://i.ytimg.com/vi/lt8Z0fNukBw/hqdefault.jpg Laut Beschreibung behandelt das Video die Entdeckung von SIR2 und NAD in der Langlebigkeitsforschung, den Zusammenhang zwischen NAD-Spiegeln und Altern, die Werbung um NMN- und NR-Supplemente, David Sinclairs Befürwortung von NMN, Ergebnisse des Interventions Testing Program zu NR, Zweifel am NAD-Rückgang mit dem Alter, NR und Long COVID sowie die Frage, ob TMG die Effekte erklärt. https://www.youtube-nocookie.com/embed/lt8Z0fNukBw 538 2025-12-27T16:57:13.000Z 2026-10-23T03:07:30.005Z https://longevityharbor.com/en/watch/m044S-fu-o8 Video description: sleep testing for midlife women with perimenopause or menopause symptoms https://i.ytimg.com/vi/m044S-fu-o8/hqdefault.jpg The description says midlife women in their 40s and 50s often assume fatigue, brain fog, irritability, weight gain, anxiety or poor sleep are simply part of aging, perimenopause or menopause, and that an undiagnosed sleep disorder may contribute. https://www.youtube-nocookie.com/embed/m044S-fu-o8 179 2026-05-31T01:01:44.000Z 2026-10-23T00:18:07.272Z https://longevityharbor.com/de/watch/m044S-fu-o8 Videobeschreibung: Schlaftests für Frauen in der Lebensmitte mit Perimenopause- oder Menopausensympt https://i.ytimg.com/vi/m044S-fu-o8/hqdefault.jpg Laut Beschreibung nehmen Frauen in ihren 40ern und 50ern oft an, Müdigkeit, Brain Fog, Reizbarkeit, Gewichtszunahme, Angst oder schlechter Schlaf seien einfach Teil des Alterns, der Perimenopause oder der Menopause; eine nicht diagnostizierte Schlafstörung könne dazu beitragen. https://www.youtube-nocookie.com/embed/m044S-fu-o8 179 2026-05-31T01:01:44.000Z 2026-10-23T00:18:07.272Z https://longevityharbor.com/en/watch/m19xgux4wWI 5 Foods That Feed Cancer Cells | Dr. Yashwant Explains #shorts #doctor #cancer #cancerprevention https://i.ytimg.com/vi/m19xgux4wWI/hqdefault.jpg Cancer-causing foods to avoid: Dr. Yashwant explains the 5 worst foods for cancer risk — and the exact mechanisms behind each one. In this episode of 'Dr. Yashwant Explains', Dr. Yashwant Singh MBBS, DGO, FRM — founder of Veganism.org, with 25 years experience in clinical medicine and nutrition — breaks down the science of how processed meat, red meat, sugary drinks, alcohol, and ultra-processed foods are linked to cancer risk — backed by peer-reviewed research from The Lancet, The BMJ, and IARC. ⚠️ Important: this video explains associations found in large studies. Diet is one risk factor among many — not a guarantee of cause and effect. Always consult your own physician. 📚 Full peer-reviewed citations are pinned in the comments. 👨‍⚕️ About Dr. Yashwant Singh MBBS, DGO, FRM: founder of Veganism.org — a non-profit research hub on health, nutrition and longevity; he has spent 25 years in the field of women's health, researching and emphasizing the role of healthy eating throughout his clinical practice. 🌿Channel @VeganismOrg provides health tips and nutrition tips via videos presented in simple elementary manner. The channel provides evidence-based health and nutrition information, and promotes vegan whole food plant-based diet. We believe healthy food is the foundation of preventing and reversing lifestyle diseases such as obesity, heart disease, diabetes, cancer, PCOS and others. We specialize in clinical plant nutrition for disease reversal and healthy aging. Encouraging the age old philosophy of food as medicine, we break down the exact biological mechanisms of specific foods and superfoods. 🔔 Subscribe to channel @VeganismOrg for evidence-based health and nutrition science delivered in simple language. #VeganismOrg #DrYashwant #DrYashwantExplains #shorts #doctor #healthtips #nutritiontips #DiseasePrevention #DiseaseReversal #VeganHealth #VeganNutrition #Veganism #ClinicalNutrition #NutritionalMedicine #FoodAsMedicine #HealthyAging #CancerPrevention #ProcessedMeat #NutritionScience #PlantBased # https://www.youtube-nocookie.com/embed/m19xgux4wWI 179 2026-06-09T05:38:53.000Z 2026-10-22T20:11:50.222Z https://longevityharbor.com/de/watch/m19xgux4wWI 5 Foods That Feed Cancer Cells | Dr. Yashwant Explains #shorts #doctor #cancer #cancerprevention https://i.ytimg.com/vi/m19xgux4wWI/hqdefault.jpg Cancer-causing foods to avoid: Dr. Yashwant explains the 5 worst foods for cancer risk — and the exact mechanisms behind each one. In this episode of 'Dr. Yashwant Explains', Dr. Yashwant Singh MBBS, DGO, FRM — founder of Veganism.org, with 25 years experience in clinical medicine and nutrition — breaks down the science of how processed meat, red meat, sugary drinks, alcohol, and ultra-processed foods are linked to cancer risk — backed by peer-reviewed research from The Lancet, The BMJ, and IARC. ⚠️ Important: this video explains associations found in large studies. Diet is one risk factor among many — not a guarantee of cause and effect. Always consult your own physician. 📚 Full peer-reviewed citations are pinned in the comments. 👨‍⚕️ About Dr. Yashwant Singh MBBS, DGO, FRM: founder of Veganism.org — a non-profit research hub on health, nutrition and longevity; he has spent 25 years in the field of women's health, researching and emphasizing the role of healthy eating throughout his clinical practice. 🌿Channel @VeganismOrg provides health tips and nutrition tips via videos presented in simple elementary manner. The channel provides evidence-based health and nutrition information, and promotes vegan whole food plant-based diet. We believe healthy food is the foundation of preventing and reversing lifestyle diseases such as obesity, heart disease, diabetes, cancer, PCOS and others. We specialize in clinical plant nutrition for disease reversal and healthy aging. Encouraging the age old philosophy of food as medicine, we break down the exact biological mechanisms of specific foods and superfoods. 🔔 Subscribe to channel @VeganismOrg for evidence-based health and nutrition science delivered in simple language. #VeganismOrg #DrYashwant #DrYashwantExplains #shorts #doctor #healthtips #nutritiontips #DiseasePrevention #DiseaseReversal #VeganHealth #VeganNutrition #Veganism #ClinicalNutrition #NutritionalMedicine #FoodAsMedicine #HealthyAging #CancerPrevention #ProcessedMeat #NutritionScience #PlantBased # https://www.youtube-nocookie.com/embed/m19xgux4wWI 179 2026-06-09T05:38:53.000Z 2026-10-22T20:11:50.222Z https://longevityharbor.com/en/watch/m38uYJdifuY Intermittent fasting and longevity: what the video description says https://i.ytimg.com/vi/m38uYJdifuY/hqdefault.jpg The description says animal studies link intermittent fasting to longer lifespan, while human evidence is still developing and mostly concerns health markers. https://www.youtube-nocookie.com/embed/m38uYJdifuY 796 2026-07-29T09:45:07.000Z 2026-10-22T23:20:33.321Z https://longevityharbor.com/de/watch/m38uYJdifuY Intervallfasten und Langlebigkeit: was die Videobeschreibung sagt https://i.ytimg.com/vi/m38uYJdifuY/hqdefault.jpg Laut Beschreibung zeigen Tierstudien einen Zusammenhang zwischen Intervallfasten und längerem Leben; die menschliche Evidenz ist noch im Entstehen und betrifft vor allem Gesundheitsmarker. https://www.youtube-nocookie.com/embed/m38uYJdifuY 796 2026-07-29T09:45:07.000Z 2026-10-22T23:20:33.321Z https://longevityharbor.com/en/watch/mAHFn3zptx0 NMN supplement video description: claimed NAD support, no results shown https://i.ytimg.com/vi/mAHFn3zptx0/hqdefault.jpg The description says NMN supports healthy NAD levels for aging and longevity, but it reports no study, dose, outcome or measured result. https://www.youtube-nocookie.com/embed/mAHFn3zptx0 164 2026-09-13T21:07:50.000Z 2026-10-22T22:16:32.780Z https://longevityharbor.com/de/watch/mAHFn3zptx0 NMN-Supplement-Videobeschreibung: behauptete NAD-Unterstützung, keine Ergebnisse gezeigt https://i.ytimg.com/vi/mAHFn3zptx0/hqdefault.jpg Die Beschreibung sagt, NMN unterstütze gesunde NAD-Werte für Altern und Langlebigkeit, nennt aber keine Studie, Dosis, Ergebnisgröße oder Messung. https://www.youtube-nocookie.com/embed/mAHFn3zptx0 164 2026-09-13T21:07:50.000Z 2026-10-22T22:16:32.780Z https://longevityharbor.com/en/watch/mD0qCPCivzo A second Aging, Geroscience and Longevity Symposium – Session one https://i.ytimg.com/vi/mD0qCPCivzo/hqdefault.jpg eLife Reviewing Editors, Sara Hägg and Dario Riccardo Valenzano, chaired this online symposium where authors whose papers have been published in our recent Aging, Geroscience and Longevity Special Issue presented their key findings. These accepted authors presented their research through live and pre-recorded presentations. Session one includes the following speakers: 00:05:18 Brooke Zanco – Monash University, Melbourne, Australia 00:24:25 Fernando Monje-Casas – CABIMER/Spanish National Research Council (CSIC), Spain 00:47:03 Sara Mouton – European Research Institute for the Biology of Ageing, University Medical Center Groningen, the Netherlands 01:06:33 Andrey A Parkhitko – Aging Institute of UPMC and the University of Pittsburgh, Pittsburgh, United States https://www.youtube-nocookie.com/embed/mD0qCPCivzo 5168 2021-03-16T12:29:56.000Z 2026-10-22T17:43:40.099Z https://longevityharbor.com/de/watch/mD0qCPCivzo A second Aging, Geroscience and Longevity Symposium – Session one https://i.ytimg.com/vi/mD0qCPCivzo/hqdefault.jpg eLife Reviewing Editors, Sara Hägg and Dario Riccardo Valenzano, chaired this online symposium where authors whose papers have been published in our recent Aging, Geroscience and Longevity Special Issue presented their key findings. These accepted authors presented their research through live and pre-recorded presentations. Session one includes the following speakers: 00:05:18 Brooke Zanco – Monash University, Melbourne, Australia 00:24:25 Fernando Monje-Casas – CABIMER/Spanish National Research Council (CSIC), Spain 00:47:03 Sara Mouton – European Research Institute for the Biology of Ageing, University Medical Center Groningen, the Netherlands 01:06:33 Andrey A Parkhitko – Aging Institute of UPMC and the University of Pittsburgh, Pittsburgh, United States https://www.youtube-nocookie.com/embed/mD0qCPCivzo 5168 2021-03-16T12:29:56.000Z 2026-10-22T17:43:40.099Z https://longevityharbor.com/en/watch/mFlS5-G726U Metformin and rapamycin for aging: mouse promise, unknown effects in healthy people https://i.ytimg.com/vi/mFlS5-G726U/hqdefault.jpg Dr. Steven Austad says metformin and rapamycin show promise in mice, but their effects on healthy people remain unknown; over 20 clinical trials are underway, and he advises against self-medicating. https://www.youtube-nocookie.com/embed/mFlS5-G726U 173 2026-09-25T07:01:32.000Z 2026-10-22T21:51:01.816Z https://longevityharbor.com/de/watch/mFlS5-G726U Metformin und Rapamycin gegen Altern: vielversprechend bei Mäusen, Wirkung bei gesunden Menschen unb https://i.ytimg.com/vi/mFlS5-G726U/hqdefault.jpg Dr. Steven Austad sagt, Metformin und Rapamycin zeigten bei Mäusen vielversprechende Ergebnisse, doch ihre Wirkung bei gesunden Menschen sei unbekannt; über 20 klinische Studien laufen, und er rät von Selbstmedikation ab. https://www.youtube-nocookie.com/embed/mFlS5-G726U 173 2026-09-25T07:01:32.000Z 2026-10-22T21:51:01.816Z https://longevityharbor.com/en/watch/mGYHqEiywqY WALS NIH Director's Lecture: Dynamic Interplay of Circadian Rhythms and Sleep on Health https://i.ytimg.com/vi/mGYHqEiywqY/hqdefault.jpg At Northwestern University Feinberg School of Medicine, Dr. Phyllis C. Zee is professor of Neurobiology, Benjamin and Virginia T. Boshes Professor in Neurology, and chief of the Division of Sleep Medicine. She also serves as director of the Center for Circadian and Sleep Medicine, where she oversees an interdisciplinary program in basic and translational sleep and circadian rhythm research; findings from her team have paved the way for innovative approaches to improve sleep and circadian health. A central theme of Dr. Zee’s research program is understanding the role of circadian-sleep interactions on the expression and development of cardiometabolic and neurologic disorders. Dr. Zee’s research has focused on the effects of age and neurodegeneration on sleep and circadian rhythms and pathophysiology of circadian sleep-wake disorders. Dr. Zee also has authored more than 300 peer-reviewed original articles, literature reviews, and book chapters on the topics of sleep, circadian rhythms, and sleep-wake disorders. She has trained over 50 pre- and post-doctoral students and has mentored numerous faculty members. For more information go to https://oir.nih.gov/wals/nih-directors-wednesday-afternoon-lecture-series-2023-2024/wals-phyllis-zee https://www.youtube-nocookie.com/embed/mGYHqEiywqY 3787 2024-04-11T13:25:59.000Z 2026-10-22T19:43:48.539Z https://longevityharbor.com/de/watch/mGYHqEiywqY WALS NIH Director's Lecture: Dynamic Interplay of Circadian Rhythms and Sleep on Health https://i.ytimg.com/vi/mGYHqEiywqY/hqdefault.jpg At Northwestern University Feinberg School of Medicine, Dr. Phyllis C. Zee is professor of Neurobiology, Benjamin and Virginia T. Boshes Professor in Neurology, and chief of the Division of Sleep Medicine. She also serves as director of the Center for Circadian and Sleep Medicine, where she oversees an interdisciplinary program in basic and translational sleep and circadian rhythm research; findings from her team have paved the way for innovative approaches to improve sleep and circadian health. A central theme of Dr. Zee’s research program is understanding the role of circadian-sleep interactions on the expression and development of cardiometabolic and neurologic disorders. Dr. Zee’s research has focused on the effects of age and neurodegeneration on sleep and circadian rhythms and pathophysiology of circadian sleep-wake disorders. Dr. Zee also has authored more than 300 peer-reviewed original articles, literature reviews, and book chapters on the topics of sleep, circadian rhythms, and sleep-wake disorders. She has trained over 50 pre- and post-doctoral students and has mentored numerous faculty members. For more information go to https://oir.nih.gov/wals/nih-directors-wednesday-afternoon-lecture-series-2023-2024/wals-phyllis-zee https://www.youtube-nocookie.com/embed/mGYHqEiywqY 3787 2024-04-11T13:25:59.000Z 2026-10-22T19:43:48.539Z https://longevityharbor.com/en/watch/mJm2DunJx-Q Podcast description: Matt Kaeberlein on rapamycin, dogs and longevity hype https://i.ytimg.com/vi/mJm2DunJx-Q/hqdefault.jpg The description says gerontologist Matt Kaeberlein discusses the Dog Aging Project with tens of thousands of dogs, why he sees rapamycin as the field's most promising compound, and how to spot longevity misinformation. https://www.youtube-nocookie.com/embed/mJm2DunJx-Q 5138 2026-08-26T07:00:00.000Z 2026-10-22T22:42:34.033Z https://longevityharbor.com/de/watch/mJm2DunJx-Q Podcast-Beschreibung: Matt Kaeberlein über Rapamycin, Hunde und Longevity-Hype https://i.ytimg.com/vi/mJm2DunJx-Q/hqdefault.jpg Laut Beschreibung spricht Gerontologe Matt Kaeberlein über das Dog Aging Project mit Zehntausenden Hunden, warum er Rapamycin als vielversprechendste Substanz des Feldes sieht und wie man Longevity-Falschinformation erkennt. https://www.youtube-nocookie.com/embed/mJm2DunJx-Q 5138 2026-08-26T07:00:00.000Z 2026-10-22T22:42:34.033Z https://longevityharbor.com/en/watch/mKtgP7XK9AY A longevity drug exists—would you take it? Nir Barzilai, M.D. | mbg Podcast https://i.ytimg.com/vi/mKtgP7XK9AY/hqdefault.jpg Subscribe to the long game to get the best well-being information—no noise: https://newsletters.mindbodygreen.com/the-long-game-signup?utm_source=youtube.com&utm_medium=social&utm_campaign=youtube--4-8-2024&utm_term=health&utm_content=new Watch more videos like this 👇 https://www.youtube.com/watch?v=ADEwtBQHqoI https://www.youtube.com/watch?v=xjKNvt5LsgM https://www.youtube.com/watch?v=_mhJ9XElJaA Today’s featured guest is Nir Barzilai, M.D., a renowned longevity researcher. “We have to spend time on our health rather than spend time on diseases," he says. In this episode, Nir and Jason discuss pharmaceutical interventions to delay aging, plus: 00:00 What are gerotherapeutics? 04:25 What you need to know about antagonistic nutrients 08:55 Why healthcare costs don’t have to increase as people live longer 12:40 SuperAgers vs. Blue Zones 15:14 What are some science-backed longevity genes? 19:54 The hallmarks of aging 22:46 How metformin extends longevity 25:03 Who is the right candidate for longevity drugs? 31:55 The best age to take a longevity drug 34:17 Lifestyle interventions for healthy aging 38:18 Is fasting actually necessary? 41:19 What to know about mTOR 43:10 How to test your biological age 48:16 What to do in your 20s and 30s for healthy aging 53:45 The role of mindset in aging 57:45 How repurposing drugs has saved lives We hope you enjoy this episode! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. ABOUT mbg: mindbodygreen. One word. Here you’ll find a 360-degree approach to wellness that weaves the mental, physical, spiritual, emotional, and environmental aspects of well-being together, because we believe that these pillars of health are all interconnected. Our values: - Science & Research - Committed to the whole you - Quality Sourced You can check us out here: https://www.mindbodygreen.com/​ Follow us on Social - @mindbodygreen Instagram: https://www.instagram.com/mindbodygreen/ F https://www.youtube-nocookie.com/embed/mKtgP7XK9AY 3735 2024-04-08T09:00:28.000Z 2026-10-22T19:32:33.490Z https://longevityharbor.com/de/watch/mKtgP7XK9AY A longevity drug exists—would you take it? Nir Barzilai, M.D. | mbg Podcast https://i.ytimg.com/vi/mKtgP7XK9AY/hqdefault.jpg Subscribe to the long game to get the best well-being information—no noise: https://newsletters.mindbodygreen.com/the-long-game-signup?utm_source=youtube.com&utm_medium=social&utm_campaign=youtube--4-8-2024&utm_term=health&utm_content=new Watch more videos like this 👇 https://www.youtube.com/watch?v=ADEwtBQHqoI https://www.youtube.com/watch?v=xjKNvt5LsgM https://www.youtube.com/watch?v=_mhJ9XElJaA Today’s featured guest is Nir Barzilai, M.D., a renowned longevity researcher. “We have to spend time on our health rather than spend time on diseases," he says. In this episode, Nir and Jason discuss pharmaceutical interventions to delay aging, plus: 00:00 What are gerotherapeutics? 04:25 What you need to know about antagonistic nutrients 08:55 Why healthcare costs don’t have to increase as people live longer 12:40 SuperAgers vs. Blue Zones 15:14 What are some science-backed longevity genes? 19:54 The hallmarks of aging 22:46 How metformin extends longevity 25:03 Who is the right candidate for longevity drugs? 31:55 The best age to take a longevity drug 34:17 Lifestyle interventions for healthy aging 38:18 Is fasting actually necessary? 41:19 What to know about mTOR 43:10 How to test your biological age 48:16 What to do in your 20s and 30s for healthy aging 53:45 The role of mindset in aging 57:45 How repurposing drugs has saved lives We hope you enjoy this episode! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. ABOUT mbg: mindbodygreen. One word. Here you’ll find a 360-degree approach to wellness that weaves the mental, physical, spiritual, emotional, and environmental aspects of well-being together, because we believe that these pillars of health are all interconnected. Our values: - Science & Research - Committed to the whole you - Quality Sourced You can check us out here: https://www.mindbodygreen.com/​ Follow us on Social - @mindbodygreen Instagram: https://www.instagram.com/mindbodygreen/ F https://www.youtube-nocookie.com/embed/mKtgP7XK9AY 3735 2024-04-08T09:00:28.000Z 2026-10-22T19:32:33.490Z https://longevityharbor.com/en/watch/mNoW-LXRFPE Arzt enthüllt: 3 Vitamine, die Ihre Beine nach 60 stärken! https://i.ytimg.com/vi/mNoW-LXRFPE/hqdefault.jpg Herzlich willkommen auf unserem Kanal! ❤️ Wünschen Sie sich auch im Alter kräftige Beine, mehr Beweglichkeit und einen sicheren Gang? Mit zunehmendem Alter können Muskelkraft, Gleichgewicht und Mobilität nachlassen. Doch eine ausgewogene Ernährung, regelmäßige Bewegung und eine ausreichende Versorgung mit wichtigen Nährstoffen können dazu beitragen, Ihre Bein- und allgemeine Gesundheit zu unterstützen. In diesem Video erfahren Sie, welche 3 wichtigen Vitamine für Menschen über 60 besonders interessant sind, welche Funktionen sie im Körper erfüllen und worauf Sie bei Ihrer Ernährung achten sollten. 🔎 Was erwartet Sie in diesem Video? ✅ 1. Vitamin D – wichtig für Knochen und Muskelfunktion Erfahren Sie, warum Vitamin D für die normale Funktion der Muskeln und den Erhalt gesunder Knochen wichtig ist und welche Lebensmittel zur Versorgung beitragen können. ✅ 2. Vitamin B12 – wichtig für Nerven und Blutbildung Vitamin B12 unterstützt die normale Funktion des Nervensystems und die Bildung roter Blutkörperchen. Wir erklären, warum die ausreichende Versorgung im höheren Alter besonders beachtet werden sollte. ✅ 3. Ein weiteres wichtiges Vitamin für den Körper Entdecken Sie, welche Rolle ein weiterer essenzieller Nährstoff für normale Körperfunktionen spielt und wie Sie Ihre Ernährung abwechslungsreich und ausgewogen gestalten können. 🦵 Weitere Themen in diesem Video: * Warum Muskelkraft und Beweglichkeit nach 60 wichtig sind * Welche Nährstoffe für Muskeln, Knochen und Nerven benötigt werden * Wie eine ausgewogene Ernährung die Gesundheit im Alter unterstützt * Welche Lebensmittel wertvolle Vitamine liefern * Warum Vitaminmangel zu gesundheitlichen Problemen beitragen kann * Weshalb Nahrungsergänzungsmittel nicht automatisch mehr Kraft bedeuten * Wie regelmäßige Bewegung und Krafttraining die Beinmuskulatur unterstützen können * Wann Sie mit Ihrem Arzt über einen möglichen Vitaminmangel sprechen sollten 💡 Wichtiger Hinweis: Vitamine sind kein Wundermittel. Eine zusätzliche Einnahme stärkt die Beine nicht auto https://www.youtube-nocookie.com/embed/mNoW-LXRFPE 613 2026-10-11T15:12:00.000Z 2026-10-22T19:54:14.146Z https://longevityharbor.com/de/watch/mNoW-LXRFPE Arzt enthüllt: 3 Vitamine, die Ihre Beine nach 60 stärken! https://i.ytimg.com/vi/mNoW-LXRFPE/hqdefault.jpg Herzlich willkommen auf unserem Kanal! ❤️ Wünschen Sie sich auch im Alter kräftige Beine, mehr Beweglichkeit und einen sicheren Gang? Mit zunehmendem Alter können Muskelkraft, Gleichgewicht und Mobilität nachlassen. Doch eine ausgewogene Ernährung, regelmäßige Bewegung und eine ausreichende Versorgung mit wichtigen Nährstoffen können dazu beitragen, Ihre Bein- und allgemeine Gesundheit zu unterstützen. In diesem Video erfahren Sie, welche 3 wichtigen Vitamine für Menschen über 60 besonders interessant sind, welche Funktionen sie im Körper erfüllen und worauf Sie bei Ihrer Ernährung achten sollten. 🔎 Was erwartet Sie in diesem Video? ✅ 1. Vitamin D – wichtig für Knochen und Muskelfunktion Erfahren Sie, warum Vitamin D für die normale Funktion der Muskeln und den Erhalt gesunder Knochen wichtig ist und welche Lebensmittel zur Versorgung beitragen können. ✅ 2. Vitamin B12 – wichtig für Nerven und Blutbildung Vitamin B12 unterstützt die normale Funktion des Nervensystems und die Bildung roter Blutkörperchen. Wir erklären, warum die ausreichende Versorgung im höheren Alter besonders beachtet werden sollte. ✅ 3. Ein weiteres wichtiges Vitamin für den Körper Entdecken Sie, welche Rolle ein weiterer essenzieller Nährstoff für normale Körperfunktionen spielt und wie Sie Ihre Ernährung abwechslungsreich und ausgewogen gestalten können. 🦵 Weitere Themen in diesem Video: * Warum Muskelkraft und Beweglichkeit nach 60 wichtig sind * Welche Nährstoffe für Muskeln, Knochen und Nerven benötigt werden * Wie eine ausgewogene Ernährung die Gesundheit im Alter unterstützt * Welche Lebensmittel wertvolle Vitamine liefern * Warum Vitaminmangel zu gesundheitlichen Problemen beitragen kann * Weshalb Nahrungsergänzungsmittel nicht automatisch mehr Kraft bedeuten * Wie regelmäßige Bewegung und Krafttraining die Beinmuskulatur unterstützen können * Wann Sie mit Ihrem Arzt über einen möglichen Vitaminmangel sprechen sollten 💡 Wichtiger Hinweis: Vitamine sind kein Wundermittel. Eine zusätzliche Einnahme stärkt die Beine nicht auto https://www.youtube-nocookie.com/embed/mNoW-LXRFPE 613 2026-10-11T15:12:00.000Z 2026-10-22T19:54:14.146Z https://longevityharbor.com/en/watch/mOC-6_xj4aw The healthy aging professor: Too much protein is a big mistake. Gut health = strength! https://i.ytimg.com/vi/mOC-6_xj4aw/hqdefault.jpg How do you build muscle and stay strong as you age? For most of us, muscle loss starts in our 30s. It’s easy to think that you can combat this and stay strong into old age by strength training and eating plenty of protein. Exercise and macros matter, but scientists are uncovering another important piece of the puzzle - a direct connection between your gut health and healthy aging. It could change how we think about staying strong as we get older. In today's episode, Professor Claire Steves - a world-leading expert in ageing and health - and Professor Tim Spector explore the gut-muscle axis - how your gut microbiome influences your muscle health. They explain why maximum protein doesn't mean maximum muscle, how gut bacteria ‘talk’ to muscle tissue, and why an unhealthy gut can make muscles resistant to growth. For listeners looking for simple ways to support their muscles today, this episode includes practical advice you can easily fit into your routine. Claire and Tim share quick daily habits and explain how to get your protein from diverse plant sources. 🌱 Try our science-backed and tasty wholefood supplement Daily30: https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=youtube&utm_campaign=d30 🌿Let your gut microbes snack on the ZOE Gut Health Bar | https://zoe.com/snackbar?utm_medium=zoe_podcast&utm_source=youtube&utm_campaign=GHB Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE: https://zoe.com/buymembership?utm_medium=zoe_podcast&utm_source=youtube&utm_campaign=BAU Follow ZOE on Instagram | https://www.instagram.com/zoe/ Timecodes: 00:00 The protein paradox: why more isn't always better 04:08 Why muscle matters for healthy aging, not just the gym 06:37 The hidden organ: how your muscles talk to your body 10:35 Why it gets harder to keep muscle as you age 11:37 Can you have a 20-year-old's muscles at 70? 13:29 Can muscle loss increase your risk of cancer? 15:51 Why skinny doesn't mean healthy 17:40 What is sarcopenia https://www.youtube-nocookie.com/embed/mOC-6_xj4aw 3661 2026-10-08T15:06:29.000Z 2026-10-22T19:43:45.419Z https://longevityharbor.com/de/watch/mOC-6_xj4aw The healthy aging professor: Too much protein is a big mistake. Gut health = strength! https://i.ytimg.com/vi/mOC-6_xj4aw/hqdefault.jpg How do you build muscle and stay strong as you age? For most of us, muscle loss starts in our 30s. It’s easy to think that you can combat this and stay strong into old age by strength training and eating plenty of protein. Exercise and macros matter, but scientists are uncovering another important piece of the puzzle - a direct connection between your gut health and healthy aging. It could change how we think about staying strong as we get older. In today's episode, Professor Claire Steves - a world-leading expert in ageing and health - and Professor Tim Spector explore the gut-muscle axis - how your gut microbiome influences your muscle health. They explain why maximum protein doesn't mean maximum muscle, how gut bacteria ‘talk’ to muscle tissue, and why an unhealthy gut can make muscles resistant to growth. For listeners looking for simple ways to support their muscles today, this episode includes practical advice you can easily fit into your routine. Claire and Tim share quick daily habits and explain how to get your protein from diverse plant sources. 🌱 Try our science-backed and tasty wholefood supplement Daily30: https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=youtube&utm_campaign=d30 🌿Let your gut microbes snack on the ZOE Gut Health Bar | https://zoe.com/snackbar?utm_medium=zoe_podcast&utm_source=youtube&utm_campaign=GHB Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE: https://zoe.com/buymembership?utm_medium=zoe_podcast&utm_source=youtube&utm_campaign=BAU Follow ZOE on Instagram | https://www.instagram.com/zoe/ Timecodes: 00:00 The protein paradox: why more isn't always better 04:08 Why muscle matters for healthy aging, not just the gym 06:37 The hidden organ: how your muscles talk to your body 10:35 Why it gets harder to keep muscle as you age 11:37 Can you have a 20-year-old's muscles at 70? 13:29 Can muscle loss increase your risk of cancer? 15:51 Why skinny doesn't mean healthy 17:40 What is sarcopenia https://www.youtube-nocookie.com/embed/mOC-6_xj4aw 3661 2026-10-08T15:06:29.000Z 2026-10-22T19:43:45.419Z https://longevityharbor.com/en/watch/mR5u3F8Y60U Your Body Has its Own Clock | Circadian Rhythm Explained https://i.ytimg.com/vi/mR5u3F8Y60U/hqdefault.jpg In this video, we explore the essential reasons why humans need sleep and how it works: 🌍 Biological Rhythms: Just like the cycles of the moon and the Earth’s orbit around the sun, our bodies follow natural cycles, including the sleep-wake cycle. 🕰️ Circadian Rhythms: Learn about your body's internal clock and how it regulates your daily sleep patterns. 🧠 Hypothalamus and Suprachiasmatic Nucleus: Discover the tiny part of your brain that has a massive impact on your sleep and wakefulness. 💡 Role of Light and Melatonin: Find out how light influences your sleep through the production of melatonin. 🌡️ Body Temperature and Sleep: Understand how body temperature affects your alertness and sleepiness, and get tips on optimizing your sleep environment. ⏰ How Much Sleep Do You Need?: Learn about different sleep needs based on age and individual differences. 🚫 Effects of Sleep Deprivation: See what happens when you miss out on sleep and how it impacts your memory and daily tasks. Whether you're a night owl, a morning person, or just curious about the science of sleep, this video is packed with valuable information to help you understand the importance of those precious hours of rest. Support: Patreon: https://buymeacoffee.com/masteryneuro Instagram: https://www.instagram.com/mastery_neuro?igsh=MXU1YWU0YjA5dHVzdQ== Discord | Mastery: https://discord.gg/EZat2VAmkF Discord | Books & Beyond: https://discord.gg/EwBqG7pBbT 🔔 Don't forget to like, subscribe, and hit the bell icon to stay updated with our latest videos! Transcript: Why do we sleep? If somehow you can avoid being unconsciousness for 8 hours every day, you can get more things done or atleast spend more time on Netflix. So why do people need to sleep and how does sleep work? One reason for this is human body’s biological rythms, the natural cycle of activity that the body must follow. Circadian Rhythm Explained Everything in the universe is following a cycle. You go through a cycle of seasons throughout the year that repeat again each year. The moon https://www.youtube-nocookie.com/embed/mR5u3F8Y60U 208 2024-06-19T16:14:54.000Z 2026-10-22T19:43:49.794Z https://longevityharbor.com/de/watch/mR5u3F8Y60U Your Body Has its Own Clock | Circadian Rhythm Explained https://i.ytimg.com/vi/mR5u3F8Y60U/hqdefault.jpg In this video, we explore the essential reasons why humans need sleep and how it works: 🌍 Biological Rhythms: Just like the cycles of the moon and the Earth’s orbit around the sun, our bodies follow natural cycles, including the sleep-wake cycle. 🕰️ Circadian Rhythms: Learn about your body's internal clock and how it regulates your daily sleep patterns. 🧠 Hypothalamus and Suprachiasmatic Nucleus: Discover the tiny part of your brain that has a massive impact on your sleep and wakefulness. 💡 Role of Light and Melatonin: Find out how light influences your sleep through the production of melatonin. 🌡️ Body Temperature and Sleep: Understand how body temperature affects your alertness and sleepiness, and get tips on optimizing your sleep environment. ⏰ How Much Sleep Do You Need?: Learn about different sleep needs based on age and individual differences. 🚫 Effects of Sleep Deprivation: See what happens when you miss out on sleep and how it impacts your memory and daily tasks. Whether you're a night owl, a morning person, or just curious about the science of sleep, this video is packed with valuable information to help you understand the importance of those precious hours of rest. Support: Patreon: https://buymeacoffee.com/masteryneuro Instagram: https://www.instagram.com/mastery_neuro?igsh=MXU1YWU0YjA5dHVzdQ== Discord | Mastery: https://discord.gg/EZat2VAmkF Discord | Books & Beyond: https://discord.gg/EwBqG7pBbT 🔔 Don't forget to like, subscribe, and hit the bell icon to stay updated with our latest videos! Transcript: Why do we sleep? If somehow you can avoid being unconsciousness for 8 hours every day, you can get more things done or atleast spend more time on Netflix. So why do people need to sleep and how does sleep work? One reason for this is human body’s biological rythms, the natural cycle of activity that the body must follow. Circadian Rhythm Explained Everything in the universe is following a cycle. You go through a cycle of seasons throughout the year that repeat again each year. The moon https://www.youtube-nocookie.com/embed/mR5u3F8Y60U 208 2024-06-19T16:14:54.000Z 2026-10-22T19:43:49.794Z https://longevityharbor.com/en/watch/mU6eC6U47lM NMN ab 40: Energie wie mit 30 – realistisch? (Studie) https://i.ytimg.com/vi/mU6eC6U47lM/hqdefault.jpg Sichere dir jetzt dein Premium-NMN und spare 15% mit Code "STEN15" ▶ https://moleqlar.com/products/uthever-nmn?sca_ref=6675416.5GZO8dgHz7 (Der Code gilt lebenslang für alle Produkte von MoleQlar) Höchste Qualität. Hergestellt in Deutschland. Zuverlässiger Partner. 📩 Noch Fragen? Dann schreibe mir gerne: Mein Instagram: https://www.instagram.com/stenschulzetraining Erwähnte Studie: https://pubmed.ncbi.nlm.nih.gov/36482258/ Wichtiger Hinweis: Dieses Video dient ausschließlich der Information und Unterhaltung. Es stellt keine medizinische Beratung, Diagnose oder Behandlungsempfehlung dar. Die dargestellten Inhalte ersetzen nicht das Gespräch mit einem Arzt oder Apotheker. Nahrungsergänzungsmittel sind kein Ersatz für eine ausgewogene Ernährung. Die Einnahme erfolgt auf eigene Verantwortung. https://www.youtube-nocookie.com/embed/mU6eC6U47lM 429 2026-03-01T17:00:00.000Z 2026-10-22T20:11:46.986Z https://longevityharbor.com/de/watch/mU6eC6U47lM NMN ab 40: Energie wie mit 30 – realistisch? (Studie) https://i.ytimg.com/vi/mU6eC6U47lM/hqdefault.jpg Sichere dir jetzt dein Premium-NMN und spare 15% mit Code "STEN15" ▶ https://moleqlar.com/products/uthever-nmn?sca_ref=6675416.5GZO8dgHz7 (Der Code gilt lebenslang für alle Produkte von MoleQlar) Höchste Qualität. Hergestellt in Deutschland. Zuverlässiger Partner. 📩 Noch Fragen? Dann schreibe mir gerne: Mein Instagram: https://www.instagram.com/stenschulzetraining Erwähnte Studie: https://pubmed.ncbi.nlm.nih.gov/36482258/ Wichtiger Hinweis: Dieses Video dient ausschließlich der Information und Unterhaltung. Es stellt keine medizinische Beratung, Diagnose oder Behandlungsempfehlung dar. Die dargestellten Inhalte ersetzen nicht das Gespräch mit einem Arzt oder Apotheker. Nahrungsergänzungsmittel sind kein Ersatz für eine ausgewogene Ernährung. Die Einnahme erfolgt auf eigene Verantwortung. https://www.youtube-nocookie.com/embed/mU6eC6U47lM 429 2026-03-01T17:00:00.000Z 2026-10-22T20:11:46.986Z https://longevityharbor.com/en/watch/mUfJRzRfdHk How calorie restriction could improve lifespan | Peter Attia & Steven Austad https://i.ytimg.com/vi/mUfJRzRfdHk/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/WNKRSiSGvGE Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode #171 of The Drive - Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules | Steve Austad, Ph.D. In this episode, Peter is joined by Steve Austad, Ph.D., a distinguished professor of biology at the University of Alabama and director of one of the Nathan Shock Centers of Excellence in aging biology. In this clip, we discuss: - The history of caloric restriction research - Clive McCay’s breakthrough nutritional studies - What caloric restriction studies in mice studies may tell us about our own health -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 60 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is https://www.youtube-nocookie.com/embed/mUfJRzRfdHk 310 2023-07-07T16:00:41.000Z 2026-10-22T17:43:38.399Z https://longevityharbor.com/de/watch/mUfJRzRfdHk How calorie restriction could improve lifespan | Peter Attia & Steven Austad https://i.ytimg.com/vi/mUfJRzRfdHk/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/WNKRSiSGvGE Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode #171 of The Drive - Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules | Steve Austad, Ph.D. In this episode, Peter is joined by Steve Austad, Ph.D., a distinguished professor of biology at the University of Alabama and director of one of the Nathan Shock Centers of Excellence in aging biology. In this clip, we discuss: - The history of caloric restriction research - Clive McCay’s breakthrough nutritional studies - What caloric restriction studies in mice studies may tell us about our own health -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 60 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is https://www.youtube-nocookie.com/embed/mUfJRzRfdHk 310 2023-07-07T16:00:41.000Z 2026-10-22T17:43:38.399Z https://longevityharbor.com/en/watch/mY3W16oUnpc Video description on 12 hallmarks of aging and longevity science https://i.ytimg.com/vi/mY3W16oUnpc/hqdefault.jpg The description says the video covers the 12 hallmarks of aging and what longevity science shows is breaking down; it credits Chris Mirabile at Novos for the hallmark content and links a waitlist. https://www.youtube-nocookie.com/embed/mY3W16oUnpc 2374 2026-02-14T19:42:34.000Z 2026-10-23T02:33:49.469Z https://longevityharbor.com/de/watch/mY3W16oUnpc Videobeschreibung zu 12 Hallmarks des Alterns und Langlebigkeitsforschung https://i.ytimg.com/vi/mY3W16oUnpc/hqdefault.jpg Laut Beschreibung behandelt das Video die 12 Hallmarks des Alterns und was laut Langlebigkeitsforschung abbaut; die Hallmark-Inhalte werden Chris Mirabile bei Novos zugeschrieben, zudem wird eine Warteliste verlinkt. https://www.youtube-nocookie.com/embed/mY3W16oUnpc 2374 2026-02-14T19:42:34.000Z 2026-10-23T02:33:49.469Z https://longevityharbor.com/en/watch/m_UAVqk5_W8 Video description: NAD⁺ decline, lifestyle boosters and supplement questions https://i.ytimg.com/vi/m_UAVqk5_W8/hqdefault.jpg The description says NAD⁺ declines naturally and links this to metabolic stress, DNA damage and mitochondrial dysfunction as precursors of age-related conditions. It says exercise and fasting are proven to boost NAD⁺ levels and asks whether supplements such as nicotinamide riboside and nicotinamide mononucleotide are a viable path. https://www.youtube-nocookie.com/embed/m_UAVqk5_W8 91 2026-04-17T15:22:54.000Z 2026-10-23T01:33:05.009Z https://longevityharbor.com/de/watch/m_UAVqk5_W8 Videobeschreibung: NAD⁺-Rückgang, Lebensstil-Booster und Supplement-Fragen https://i.ytimg.com/vi/m_UAVqk5_W8/hqdefault.jpg Laut Beschreibung sinkt NAD⁺ auf natürliche Weise und wird mit metabolischem Stress, DNA-Schäden und mitochondrialer Dysfunktion als Vorstufen altersbezogener Zustände verbunden. Sport und Fasten sollen NAD⁺ nachweislich erhöhen; gefragt wird, ob Supplemente wie Nicotinamid-Ribosid und Nicotinamid-Mononukleotid ein gangbarer Weg sind. https://www.youtube-nocookie.com/embed/m_UAVqk5_W8 91 2026-04-17T15:22:54.000Z 2026-10-23T01:33:05.009Z https://longevityharbor.com/en/watch/maErI0s8v8g Gesund altern durch Bewegung - ein Podcast mit unserer Gesundheitsexpertin Jutta Suffner https://i.ytimg.com/vi/maErI0s8v8g/hqdefault.jpg Wer kennt ihn nicht…den „inneren“ Schweinehund, der insbesondere abends in Rudeln vor unserer Couch sitzt. Doch es lohnt sich, diesen liebevoll in sein Körbchen zu verfrachten und die Beine in die Hand zu nehmen. Viele Studien zeigen, dass ein regelmäßiges Kraft- Ausdauertraining die Immunbotenstoffe im Körper ansteigen lässt. Dies reduziert nachweislich die sogenannten stillen Entzündungen, die Ursache (fast) jeder Krankheit sind. https://www.youtube-nocookie.com/embed/maErI0s8v8g 206 2023-01-26T15:59:20.000Z 2026-10-22T18:32:13.286Z https://longevityharbor.com/de/watch/maErI0s8v8g Gesund altern durch Bewegung - ein Podcast mit unserer Gesundheitsexpertin Jutta Suffner https://i.ytimg.com/vi/maErI0s8v8g/hqdefault.jpg Wer kennt ihn nicht…den „inneren“ Schweinehund, der insbesondere abends in Rudeln vor unserer Couch sitzt. Doch es lohnt sich, diesen liebevoll in sein Körbchen zu verfrachten und die Beine in die Hand zu nehmen. Viele Studien zeigen, dass ein regelmäßiges Kraft- Ausdauertraining die Immunbotenstoffe im Körper ansteigen lässt. Dies reduziert nachweislich die sogenannten stillen Entzündungen, die Ursache (fast) jeder Krankheit sind. https://www.youtube-nocookie.com/embed/maErI0s8v8g 206 2023-01-26T15:59:20.000Z 2026-10-22T18:32:13.286Z https://longevityharbor.com/en/watch/mgjYHn-B6d8 Exercise description claims cellular and brain anti-aging effects https://i.ytimg.com/vi/mgjYHn-B6d8/hqdefault.jpg The description presents exercise as a powerful tool against aging at cellular and brain level, citing an exercise–lactate–lactylation pathway and brain-region growth, but gives no study details. https://www.youtube-nocookie.com/embed/mgjYHn-B6d8 389 2026-04-29T20:14:27.000Z 2026-10-23T01:20:03.834Z https://longevityharbor.com/de/watch/mgjYHn-B6d8 Beschreibung behauptet zelluläre und hirnbezogene Anti-Aging-Effekte durch Bewegung https://i.ytimg.com/vi/mgjYHn-B6d8/hqdefault.jpg Die Beschreibung stellt Bewegung als starkes Mittel gegen das Altern auf zellulärer und Hirnebene dar, nennt einen Exercise-Laktat-Laktatylierungs-Weg und Hirnregionen-Wachstum, ohne Studiendetails zu liefern. https://www.youtube-nocookie.com/embed/mgjYHn-B6d8 389 2026-04-29T20:14:27.000Z 2026-10-23T01:20:03.834Z https://longevityharbor.com/en/watch/mhMcnLr7loU You've Been Fasting All Wrong (feat. Dr. Valter Longo) https://i.ytimg.com/vi/mhMcnLr7loU/hqdefault.jpg Dr. Valter Longo recommends just 12 to 13 hours of daily fasting for most people — not the 16+ hour marathons many self-respecting biohackers swear by. He says going longer every day could backfire, triggering nutrient deficiencies and long-term issues. You may find this podcast surprising, and you may change your diet on the back of it. Dr. Valter Longo is one of the world’s leading experts on longevity, fasting, and disease prevention. He’s the creator of the Fasting-Mimicking Diet, author of The Longevity Diet, and a pioneer in nutrition-based healthspan research. Follow Dr. Valter Longo on Instagram: https://www.instagram.com/prof_valterlongo/?hl=en Join 30k+ weekly biohackers who receive the latest tech + techniques + reviews + insider biohacking news by signing up for the weekly newsletter here. https://www.youtube-nocookie.com/embed/mhMcnLr7loU 2192 2025-09-01T12:05:43.000Z 2026-10-22T18:54:08.093Z https://longevityharbor.com/de/watch/mhMcnLr7loU You've Been Fasting All Wrong (feat. Dr. Valter Longo) https://i.ytimg.com/vi/mhMcnLr7loU/hqdefault.jpg Dr. Valter Longo recommends just 12 to 13 hours of daily fasting for most people — not the 16+ hour marathons many self-respecting biohackers swear by. He says going longer every day could backfire, triggering nutrient deficiencies and long-term issues. You may find this podcast surprising, and you may change your diet on the back of it. Dr. Valter Longo is one of the world’s leading experts on longevity, fasting, and disease prevention. He’s the creator of the Fasting-Mimicking Diet, author of The Longevity Diet, and a pioneer in nutrition-based healthspan research. Follow Dr. Valter Longo on Instagram: https://www.instagram.com/prof_valterlongo/?hl=en Join 30k+ weekly biohackers who receive the latest tech + techniques + reviews + insider biohacking news by signing up for the weekly newsletter here. https://www.youtube-nocookie.com/embed/mhMcnLr7loU 2192 2025-09-01T12:05:43.000Z 2026-10-22T18:54:08.093Z https://longevityharbor.com/en/watch/mi2l_JDAe4w Age of a single cell! (epigenetic clocks) https://i.ytimg.com/vi/mi2l_JDAe4w/hqdefault.jpg There are many different biomarkers that have now been used to develop so-called aging clocks that predict biological or chronological age. But one biomarker that has seen the most advances so far are epigenetic clocks that use DNA methylation as a measurement. Currently, these tools work by using "bulk" data however this misses acquisition of heterogeneity in a dataset. But, a new publication in Nature Aging has now developed a framework for predicting age of a single cell! In this video we discuss how. P.S I interviewed the lead author of the paper - you can view here - https://youtu.be/5LcgovlTxIM Find me on Twitter - https://twitter.com/EleanorSheekey Support the channel through PayPal - https://paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB through Patreon - https://www.patreon.com/TheSheekeyScienceShow TIMESTAMPS: Intro - 00:00 Epigenetic clocks - 00:50 Age of a single cell - 03:00 Applications of single cell age - 08:15 References: Trapp, A., Kerepesi, C. & Gladyshev, V.N. Profiling epigenetic age in single cells. Nat Aging 1, 1189–1201 (2021). https://doi.org/10.1038/s43587-021-00134-3 Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com https://www.youtube-nocookie.com/embed/mi2l_JDAe4w 682 2022-01-19T16:01:05.000Z 2026-10-22T17:43:35.162Z https://longevityharbor.com/de/watch/mi2l_JDAe4w Age of a single cell! (epigenetic clocks) https://i.ytimg.com/vi/mi2l_JDAe4w/hqdefault.jpg There are many different biomarkers that have now been used to develop so-called aging clocks that predict biological or chronological age. But one biomarker that has seen the most advances so far are epigenetic clocks that use DNA methylation as a measurement. Currently, these tools work by using "bulk" data however this misses acquisition of heterogeneity in a dataset. But, a new publication in Nature Aging has now developed a framework for predicting age of a single cell! In this video we discuss how. P.S I interviewed the lead author of the paper - you can view here - https://youtu.be/5LcgovlTxIM Find me on Twitter - https://twitter.com/EleanorSheekey Support the channel through PayPal - https://paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB through Patreon - https://www.patreon.com/TheSheekeyScienceShow TIMESTAMPS: Intro - 00:00 Epigenetic clocks - 00:50 Age of a single cell - 03:00 Applications of single cell age - 08:15 References: Trapp, A., Kerepesi, C. & Gladyshev, V.N. Profiling epigenetic age in single cells. Nat Aging 1, 1189–1201 (2021). https://doi.org/10.1038/s43587-021-00134-3 Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com https://www.youtube-nocookie.com/embed/mi2l_JDAe4w 682 2022-01-19T16:01:05.000Z 2026-10-22T17:43:35.162Z https://longevityharbor.com/en/watch/mim6KgNDDb0 5 Science-Backed Exercises That Reverse Aging https://i.ytimg.com/vi/mim6KgNDDb0/hqdefault.jpg 🔥 Get the complete system our students use daily ➡️ https://movesmethodprogram.com/getkit Vanja reveals five scientifically-proven movements that reverse the aging process by rebuilding strength, mobility, and independence - tested on thousands of students from their 30s to 70s. ⭐️ Can't squat properly? Master the fundamentals first ➡️ https://youtu.be/-KICl7fv928?si=7jTtmrhoA7k28BuS =========================== 🎯 TRANSFORM YOUR MOVEMENT Want to work one on one with me and my team to improve your mobility? Go here to apply now 👉🏼 https://movesmethodprogram.com/apply Fuel your Body 👉🏼 https://www.suppleblends.com/ =========================== CONNECT WITH US Vanja ➡️ https://www.instagram.com/vanja.moves/ Josh ➡️ https://www.instagram.com/joshfearfit/ =========================== COMMUNITY & ENGAGEMENT 💬 Tell us which exercise you're starting with today and share this with someone who needs to see it! 📸 Give this video a like if you're ready to reverse your aging story =========================== RESOURCES MENTIONED Chair or door frame for squat assistance Books or step for heel elevation Pull-up bar, tree branch, or sturdy rail for hanging Low stool or box for sit-to-stand progressions =========================== DISCLAIMERS This video is for educational purposes. Some links may be affiliate links which means we earn a small commission at no extra cost to you. Always consult a healthcare professional before starting any new exercise program. ⏰ TIMECODES ⏰ 0:00 Why Your Body Isn't Broken Because of Age 0:57 Exercise #1: Hanging (Grip Strength = Longevity) 2:45 Exercise #2: Deep Squat (Human Resting Position) 4:36 Exercise #3: Sit-to-Stand (Independence Test) 6:07 Exercise #4: Hip Mobility (Fall-Proof Foundation) 7:44 Exercise #5: Isometric Core Stability (Anti-Fall Armor) 9:31 These Are Human Non-Negotiables #MovesMethod #ReverseAging #Vanja #ScienceBackedFitness #HealthyAging Discover how hanging builds grip strength (linked to longevity), squatting maintains independence, and isometric holds creat https://www.youtube-nocookie.com/embed/mim6KgNDDb0 605 2025-10-02T12:01:35.000Z 2026-10-22T17:43:36.957Z https://longevityharbor.com/de/watch/mim6KgNDDb0 5 Science-Backed Exercises That Reverse Aging https://i.ytimg.com/vi/mim6KgNDDb0/hqdefault.jpg 🔥 Get the complete system our students use daily ➡️ https://movesmethodprogram.com/getkit Vanja reveals five scientifically-proven movements that reverse the aging process by rebuilding strength, mobility, and independence - tested on thousands of students from their 30s to 70s. ⭐️ Can't squat properly? Master the fundamentals first ➡️ https://youtu.be/-KICl7fv928?si=7jTtmrhoA7k28BuS =========================== 🎯 TRANSFORM YOUR MOVEMENT Want to work one on one with me and my team to improve your mobility? Go here to apply now 👉🏼 https://movesmethodprogram.com/apply Fuel your Body 👉🏼 https://www.suppleblends.com/ =========================== CONNECT WITH US Vanja ➡️ https://www.instagram.com/vanja.moves/ Josh ➡️ https://www.instagram.com/joshfearfit/ =========================== COMMUNITY & ENGAGEMENT 💬 Tell us which exercise you're starting with today and share this with someone who needs to see it! 📸 Give this video a like if you're ready to reverse your aging story =========================== RESOURCES MENTIONED Chair or door frame for squat assistance Books or step for heel elevation Pull-up bar, tree branch, or sturdy rail for hanging Low stool or box for sit-to-stand progressions =========================== DISCLAIMERS This video is for educational purposes. Some links may be affiliate links which means we earn a small commission at no extra cost to you. Always consult a healthcare professional before starting any new exercise program. ⏰ TIMECODES ⏰ 0:00 Why Your Body Isn't Broken Because of Age 0:57 Exercise #1: Hanging (Grip Strength = Longevity) 2:45 Exercise #2: Deep Squat (Human Resting Position) 4:36 Exercise #3: Sit-to-Stand (Independence Test) 6:07 Exercise #4: Hip Mobility (Fall-Proof Foundation) 7:44 Exercise #5: Isometric Core Stability (Anti-Fall Armor) 9:31 These Are Human Non-Negotiables #MovesMethod #ReverseAging #Vanja #ScienceBackedFitness #HealthyAging Discover how hanging builds grip strength (linked to longevity), squatting maintains independence, and isometric holds creat https://www.youtube-nocookie.com/embed/mim6KgNDDb0 605 2025-10-02T12:01:35.000Z 2026-10-22T17:43:36.957Z https://longevityharbor.com/en/watch/mkRLjhZIVy4 OHBM 2025 symposium talk on circadian sleep, cognition and brain integrity in healthy older adults https://i.ytimg.com/vi/mkRLjhZIVy4/hqdefault.jpg The description lists a symposium talk by Stella de Haan at OHBM 2025 on circadian sleep regulation, cognition and brain structural-functional integrity in healthy older adults. The description gives no methods, results or conclusions. https://www.youtube-nocookie.com/embed/mkRLjhZIVy4 760 2025-12-06T17:30:24.000Z 2026-10-23T03:19:13.086Z https://longevityharbor.com/de/watch/mkRLjhZIVy4 OHBM-2025-Symposiumsvortrag zu zirkadianer Schlafregulation, Kognition und Hirnintegrität bei gesund https://i.ytimg.com/vi/mkRLjhZIVy4/hqdefault.jpg Die Beschreibung nennt einen Symposiumsvortrag von Stella de Haan beim OHBM 2025 zu zirkadianer Schlafregulation, Kognition und strukturell-funktioneller Hirnintegrität bei gesunden älteren Erwachsenen. Methoden, Ergebnisse oder Schlussfolgerungen enthält die Beschreibung nicht. https://www.youtube-nocookie.com/embed/mkRLjhZIVy4 760 2025-12-06T17:30:24.000Z 2026-10-23T03:19:13.086Z https://longevityharbor.com/en/watch/mkXAcIXmm3A Just trying to correct some of the information on NAD versus NMN as a longevity based anti-aging https://i.ytimg.com/vi/mkXAcIXmm3A/hqdefault.jpg Just trying to correct some of the information on NAD versus NMN as a longevity based anti-aging supplement #nad #nmn #nmnsupplement #nadsupplement #supplementsthatwork #supplements https://www.youtube-nocookie.com/embed/mkXAcIXmm3A 95 2024-10-25T18:02:16.000Z 2026-10-22T19:32:37.467Z https://longevityharbor.com/de/watch/mkXAcIXmm3A Just trying to correct some of the information on NAD versus NMN as a longevity based anti-aging https://i.ytimg.com/vi/mkXAcIXmm3A/hqdefault.jpg Just trying to correct some of the information on NAD versus NMN as a longevity based anti-aging supplement #nad #nmn #nmnsupplement #nadsupplement #supplementsthatwork #supplements https://www.youtube-nocookie.com/embed/mkXAcIXmm3A 95 2024-10-25T18:02:16.000Z 2026-10-22T19:32:37.467Z https://longevityharbor.com/en/watch/mmzgvwG5lsQ NMN as a precursor of NAD⁺: a shop series video description https://i.ytimg.com/vi/mmzgvwG5lsQ/hqdefault.jpg The description says NMN is a precursor of NAD⁺, which cells need for energy processes, repair mechanisms and enzyme systems, and that NAD⁺ levels often fall with age; it presents NMN as a possible building block and promises a pragmatic look at the data. https://www.youtube-nocookie.com/embed/mmzgvwG5lsQ 123 2025-12-29T18:30:13.000Z 2026-10-23T03:04:46.630Z https://longevityharbor.com/de/watch/mmzgvwG5lsQ NMN als Vorstufe von NAD⁺: Beschreibung eines Shop-Serienvideos https://i.ytimg.com/vi/mmzgvwG5lsQ/hqdefault.jpg Laut Beschreibung ist NMN eine Vorstufe von NAD⁺, das Zellen unter anderem für Energieprozesse, Reparaturmechanismen und Enzymsysteme brauchen; NAD⁺-Spiegel sinken mit dem Alter häufig. NMN wird als möglicher Baustein vorgestellt, eine pragmatische Einordnung der Datenlage wird angekündigt. https://www.youtube-nocookie.com/embed/mmzgvwG5lsQ 123 2025-12-29T18:30:13.000Z 2026-10-23T03:04:46.630Z https://longevityharbor.com/en/watch/n2eZadOm4y8 Session 5 Healthy Aging Series Align Biological Clocks: Utilizing the Circadian Code for Gut Issues https://i.ytimg.com/vi/n2eZadOm4y8/hqdefault.jpg This 5-part webinar series, presented by Guest Dr. Shilpi Gupta, will include the following talks: Decoding Biological Clocks Leveraging Circadian Rhythms for Optimal Sleep Aligning Your Clock for Weight Loss Hydration Rhythms Utilizing the Circadian Code to address Gut Issues This series delves into the diverse Circadian Rhythms within our bodies, followed by discussions on science-backed techniques to harness our biological clock for enhanced well-being. For this series the speaker will be virtual. You can either attend in-person at the Civic Centre Resource Library, or virtually on Zoom. For more information about Dr. Gupta: curiousandcreativelab.ca Click here to place a hold on her book based on her previous series. Please note that this session is intended for your personal learning purposes and does not provide direct medical advice. Any information learned in this session does not replace information that you receive from your family doctor or healthcare providers. This is a recording of a live virtual program on April 25, 2024. https://www.youtube-nocookie.com/embed/n2eZadOm4y8 3521 2024-05-05T12:45:05.000Z 2026-10-22T18:54:02.061Z https://longevityharbor.com/de/watch/n2eZadOm4y8 Session 5 Healthy Aging Series Align Biological Clocks: Utilizing the Circadian Code for Gut Issues https://i.ytimg.com/vi/n2eZadOm4y8/hqdefault.jpg This 5-part webinar series, presented by Guest Dr. Shilpi Gupta, will include the following talks: Decoding Biological Clocks Leveraging Circadian Rhythms for Optimal Sleep Aligning Your Clock for Weight Loss Hydration Rhythms Utilizing the Circadian Code to address Gut Issues This series delves into the diverse Circadian Rhythms within our bodies, followed by discussions on science-backed techniques to harness our biological clock for enhanced well-being. For this series the speaker will be virtual. You can either attend in-person at the Civic Centre Resource Library, or virtually on Zoom. For more information about Dr. Gupta: curiousandcreativelab.ca Click here to place a hold on her book based on her previous series. Please note that this session is intended for your personal learning purposes and does not provide direct medical advice. Any information learned in this session does not replace information that you receive from your family doctor or healthcare providers. This is a recording of a live virtual program on April 25, 2024. https://www.youtube-nocookie.com/embed/n2eZadOm4y8 3521 2024-05-05T12:45:05.000Z 2026-10-22T18:54:02.061Z https://longevityharbor.com/en/watch/n5kWf0pvEkc Exercise and Healthy Aging: Expert Q&A https://i.ytimg.com/vi/n5kWf0pvEkc/hqdefault.jpg How does exercise play a role in healthy aging? NIA experts Luigi Ferrucci, M.D., Ph.D. and Lyndon Joseph, Ph.D. answer common questions about exercise and physical activity including how much exercise you need as you age, the benefits of exercise for older adults, and how to get started. Learn more about the research on exercise and aging: https://bit.ly/3KWH9BY All comments must conform to NIA's comments policy: https://go.nia.nih.gov/3VazFjD #exercise #healthyaging #aging #physicalactivity https://www.youtube-nocookie.com/embed/n5kWf0pvEkc 1170 2022-09-15T17:14:49.000Z 2026-10-22T17:43:36.933Z https://longevityharbor.com/de/watch/n5kWf0pvEkc Exercise and Healthy Aging: Expert Q&A https://i.ytimg.com/vi/n5kWf0pvEkc/hqdefault.jpg How does exercise play a role in healthy aging? NIA experts Luigi Ferrucci, M.D., Ph.D. and Lyndon Joseph, Ph.D. answer common questions about exercise and physical activity including how much exercise you need as you age, the benefits of exercise for older adults, and how to get started. Learn more about the research on exercise and aging: https://bit.ly/3KWH9BY All comments must conform to NIA's comments policy: https://go.nia.nih.gov/3VazFjD #exercise #healthyaging #aging #physicalactivity https://www.youtube-nocookie.com/embed/n5kWf0pvEkc 1170 2022-09-15T17:14:49.000Z 2026-10-22T17:43:36.933Z https://longevityharbor.com/en/watch/nErEp5JXhjE Book overview: Why We Die on aging biology and longevity claims https://i.ytimg.com/vi/nErEp5JXhjE/hqdefault.jpg This independent audio-podcast overview of Venki Ramakrishnan's book describes aging as interconnected changes and stresses that animal or biomarker results do not prove safe human lifespan or healthspan benefits. https://www.youtube-nocookie.com/embed/nErEp5JXhjE 2291 2026-08-24T10:45:40.000Z 2026-10-22T22:47:16.268Z https://longevityharbor.com/de/watch/nErEp5JXhjE Buchüberblick: Why We Die über Alternsbiologie und Langlebigkeitsaussagen https://i.ytimg.com/vi/nErEp5JXhjE/hqdefault.jpg Dieser unabhängige Audio-Podcast-Überblick über Venki Ramakrishnans Buch beschreibt Altern als miteinander verbundene Veränderungen und betont, dass Tier- oder Biomarker-Ergebnisse keine sicheren Vorteile für menschliche Lebens- oder Gesundheitsspanne belegen. https://www.youtube-nocookie.com/embed/nErEp5JXhjE 2291 2026-08-24T10:45:40.000Z 2026-10-22T22:47:16.268Z https://longevityharbor.com/en/watch/nFFr1bifEkM The Guide to Intermittent Fasting for Health and Longevity https://i.ytimg.com/vi/nFFr1bifEkM/hqdefault.jpg 1. Main Intermittent Fasting Methods 16/8 Fasting (16-Hour Fast): Restricting eating to an 8-hour window (e.g., 12:00 PM to 8:00 PM) and fasting for the remaining 16 hours. 5:2 Diet: Eating normally for 5 days a week and capping daily intake at 500–600 kcal on the remaining 2 days. 24-Hour Fast (Eat-Stop-Eat): Fasting for a full 24-hour period 1–2 times per week. One Meal a Day (OMAD): Consuming only one nutrient-dense meal per day. 2. Health & Longevity Benefits for People Over 40 Weight Loss & Fat Burning: Time-restricted eating naturally reduces calorie intake and lowers insulin levels, prompting the body to burn stored fat for energy while releasing growth hormone to preserve muscle. A study from Beijing Sport University on 600 obese adults aged 40+ showed an average weight loss of ~2 kg and a significant BMI drop over 2 to 6 weeks of 16-hour fasting. Diabetes Prevention: Fasting stabilizes blood sugar and improves insulin sensitivity by giving pancreatic cells periodic rest. Research from Yonsei and Inha Universities found an average reduction in fasting blood glucose of 4.16 mg/dL among fast participants. Cardiovascular Protection: Reducing frequent insulin spikes minimizes vascular inflammation, while activating autophagy (cellular repair) to protect blood vessel health. Boosted Energy & Mood: A study on men aged 50–70 combining twice-weekly fasts with mild calorie restriction showed increased vitality alongside significant reductions in tension, anger, and confusion, likely driven by increased brain serotonin and endorphin production. Cognitive Enhancement: A 2024 study led by the NIH on adults with an average age of 65 demonstrated activated neural connectivity in the hippocampus, suppressed neuroinflammation, and a 12% average score increase on memory tests after 6 months of intermittent fasting. 3. Important Precautions & Success Tips Preserving Muscle Mass: Fasts exceeding 16 hours may increase muscle breakdown; combining fasting with strength training and adequate protein intake helps retain musc https://www.youtube-nocookie.com/embed/nFFr1bifEkM 586 2026-09-24T22:34:28.000Z 2026-10-22T19:54:18.120Z https://longevityharbor.com/de/watch/nFFr1bifEkM The Guide to Intermittent Fasting for Health and Longevity https://i.ytimg.com/vi/nFFr1bifEkM/hqdefault.jpg 1. Main Intermittent Fasting Methods 16/8 Fasting (16-Hour Fast): Restricting eating to an 8-hour window (e.g., 12:00 PM to 8:00 PM) and fasting for the remaining 16 hours. 5:2 Diet: Eating normally for 5 days a week and capping daily intake at 500–600 kcal on the remaining 2 days. 24-Hour Fast (Eat-Stop-Eat): Fasting for a full 24-hour period 1–2 times per week. One Meal a Day (OMAD): Consuming only one nutrient-dense meal per day. 2. Health & Longevity Benefits for People Over 40 Weight Loss & Fat Burning: Time-restricted eating naturally reduces calorie intake and lowers insulin levels, prompting the body to burn stored fat for energy while releasing growth hormone to preserve muscle. A study from Beijing Sport University on 600 obese adults aged 40+ showed an average weight loss of ~2 kg and a significant BMI drop over 2 to 6 weeks of 16-hour fasting. Diabetes Prevention: Fasting stabilizes blood sugar and improves insulin sensitivity by giving pancreatic cells periodic rest. Research from Yonsei and Inha Universities found an average reduction in fasting blood glucose of 4.16 mg/dL among fast participants. Cardiovascular Protection: Reducing frequent insulin spikes minimizes vascular inflammation, while activating autophagy (cellular repair) to protect blood vessel health. Boosted Energy & Mood: A study on men aged 50–70 combining twice-weekly fasts with mild calorie restriction showed increased vitality alongside significant reductions in tension, anger, and confusion, likely driven by increased brain serotonin and endorphin production. Cognitive Enhancement: A 2024 study led by the NIH on adults with an average age of 65 demonstrated activated neural connectivity in the hippocampus, suppressed neuroinflammation, and a 12% average score increase on memory tests after 6 months of intermittent fasting. 3. Important Precautions & Success Tips Preserving Muscle Mass: Fasts exceeding 16 hours may increase muscle breakdown; combining fasting with strength training and adequate protein intake helps retain musc https://www.youtube-nocookie.com/embed/nFFr1bifEkM 586 2026-09-24T22:34:28.000Z 2026-10-22T19:54:18.120Z https://longevityharbor.com/en/watch/nFRrC9gLeXA Does NMN Actually Increase VO2 MAX? https://i.ytimg.com/vi/nFRrC9gLeXA/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Related episodes: Scientists Debate How to Live Longer & Longevity Drugs: https://youtu.be/EebH_taOlAA Supplement Industry Secrets: What They Aren't Telling You About NAD+ & NMN" https://youtu.be/OgsfIUfuyqk NAD+ boosters are supplements designed to enhance levels of nicotinamide adenine dinucleotide (NAD+), a central coenzyme found in all living cells and involved in innumerable biochemical reactions that include DNA repair, glycolysis, stress responses, and more. As we age, NAD+ levels naturally decline. Supplements containing NAD+ precursors such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) aim to counteract this decline by providing the body with the building blocks it needs to restore NAD+ levels. Proponents of these supplements suggest that they may support better energy metabolism, improved cognitive function, and even promote longevity. However, while early research is promising, it's important to approach these supplements with caution and consult healthcare professionals to understand their potential benefits and limitations. For this episode, we examined a 2022 study that looked at the effects of NMN supplementation on VO2 max, or the maximum amount of oxygen a person can use during intense exercise, in amateur runners. Matt and Nick review the study, discuss its limitations, and provide their takes on whether NMN actually improves endurance and aerobic capacity during exercise—and thus whether we should take the claims of NMN supplement sellers seriously. 0:00 Intro 0:26 Introduction to NMN and Supplement Claims (GO2MAX) 4:34 Study Motivation and Context 8:14 Study Design and Methodology 13:52 Study Results - VO2 Max 14:55 VT1, VT2 and Study Limitations 18:00 Conclusion, Future Outlook, Cheaper Alternatives Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor sh https://www.youtube-nocookie.com/embed/nFRrC9gLeXA 1449 2024-09-03T14:00:45.000Z 2026-10-22T19:32:38.664Z https://longevityharbor.com/de/watch/nFRrC9gLeXA Does NMN Actually Increase VO2 MAX? https://i.ytimg.com/vi/nFRrC9gLeXA/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Related episodes: Scientists Debate How to Live Longer & Longevity Drugs: https://youtu.be/EebH_taOlAA Supplement Industry Secrets: What They Aren't Telling You About NAD+ & NMN" https://youtu.be/OgsfIUfuyqk NAD+ boosters are supplements designed to enhance levels of nicotinamide adenine dinucleotide (NAD+), a central coenzyme found in all living cells and involved in innumerable biochemical reactions that include DNA repair, glycolysis, stress responses, and more. As we age, NAD+ levels naturally decline. Supplements containing NAD+ precursors such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) aim to counteract this decline by providing the body with the building blocks it needs to restore NAD+ levels. Proponents of these supplements suggest that they may support better energy metabolism, improved cognitive function, and even promote longevity. However, while early research is promising, it's important to approach these supplements with caution and consult healthcare professionals to understand their potential benefits and limitations. For this episode, we examined a 2022 study that looked at the effects of NMN supplementation on VO2 max, or the maximum amount of oxygen a person can use during intense exercise, in amateur runners. Matt and Nick review the study, discuss its limitations, and provide their takes on whether NMN actually improves endurance and aerobic capacity during exercise—and thus whether we should take the claims of NMN supplement sellers seriously. 0:00 Intro 0:26 Introduction to NMN and Supplement Claims (GO2MAX) 4:34 Study Motivation and Context 8:14 Study Design and Methodology 13:52 Study Results - VO2 Max 14:55 VT1, VT2 and Study Limitations 18:00 Conclusion, Future Outlook, Cheaper Alternatives Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor sh https://www.youtube-nocookie.com/embed/nFRrC9gLeXA 1449 2024-09-03T14:00:45.000Z 2026-10-22T19:32:38.664Z https://longevityharbor.com/en/watch/nJ2iU_cagXY Chronic Stress, Sleep & Circadian Rhythms https://i.ytimg.com/vi/nJ2iU_cagXY/hqdefault.jpg Welcome to Lesson 15 of the Human Biology Masterclass — the final lesson of Section 3: Control and Communication. In the previous lessons, we explored the nervous system, the brain, and the endocrine system. Now we bring these systems together to understand what happens when modern life repeatedly challenges the body's ability to adapt. In this lesson, you'll learn: • What chronic stress is and what the concept of allostatic load means • How repeated stress can affect the cardiovascular, immune, metabolic, and nervous systems • How prolonged stress is associated with changes in brain function and biological ageing • Why sleep is an active biological process rather than simply passive rest • How sleep deprivation affects cognition, mood, cardiovascular function, immunity, and metabolism • Why insufficient sleep is associated with changes in appetite regulation and metabolic health • What the glymphatic system is and how sleep may contribute to brain waste clearance • How circadian rhythms regulate daily patterns of physiology and behaviour • The role of the suprachiasmatic nucleus as a central circadian clock • How environmental light helps synchronize the body's internal clock • Why consistent sleep and wake timing can support healthy circadian regulation • How caffeine, evening light exposure, bedroom environment, and pre-sleep routines can influence sleep • Why chronic stress, sleep disruption, and circadian misalignment can interact with one another Stress is not inherently harmful. Acute stress is an important adaptive response that helps the body respond to challenges. The problem arises when stress becomes persistent and recovery is repeatedly disrupted. Sleep is equally important. During sleep, the brain and body remain biologically active, supporting processes involved in memory, emotional regulation, metabolism, immune function, and physiological recovery. Finally, circadian biology reminds us that human physiology is influenced not only by what we do, but also by when we do it. What's Next? In S https://www.youtube-nocookie.com/embed/nJ2iU_cagXY 513 2026-09-15T11:27:41.000Z 2026-10-22T18:54:02.100Z https://longevityharbor.com/de/watch/nJ2iU_cagXY Chronic Stress, Sleep & Circadian Rhythms https://i.ytimg.com/vi/nJ2iU_cagXY/hqdefault.jpg Welcome to Lesson 15 of the Human Biology Masterclass — the final lesson of Section 3: Control and Communication. In the previous lessons, we explored the nervous system, the brain, and the endocrine system. Now we bring these systems together to understand what happens when modern life repeatedly challenges the body's ability to adapt. In this lesson, you'll learn: • What chronic stress is and what the concept of allostatic load means • How repeated stress can affect the cardiovascular, immune, metabolic, and nervous systems • How prolonged stress is associated with changes in brain function and biological ageing • Why sleep is an active biological process rather than simply passive rest • How sleep deprivation affects cognition, mood, cardiovascular function, immunity, and metabolism • Why insufficient sleep is associated with changes in appetite regulation and metabolic health • What the glymphatic system is and how sleep may contribute to brain waste clearance • How circadian rhythms regulate daily patterns of physiology and behaviour • The role of the suprachiasmatic nucleus as a central circadian clock • How environmental light helps synchronize the body's internal clock • Why consistent sleep and wake timing can support healthy circadian regulation • How caffeine, evening light exposure, bedroom environment, and pre-sleep routines can influence sleep • Why chronic stress, sleep disruption, and circadian misalignment can interact with one another Stress is not inherently harmful. Acute stress is an important adaptive response that helps the body respond to challenges. The problem arises when stress becomes persistent and recovery is repeatedly disrupted. Sleep is equally important. During sleep, the brain and body remain biologically active, supporting processes involved in memory, emotional regulation, metabolism, immune function, and physiological recovery. Finally, circadian biology reminds us that human physiology is influenced not only by what we do, but also by when we do it. What's Next? In S https://www.youtube-nocookie.com/embed/nJ2iU_cagXY 513 2026-09-15T11:27:41.000Z 2026-10-22T18:54:02.100Z https://longevityharbor.com/en/watch/nKhAjUGxpmM Video description: why the body is said to age faster after 75 https://i.ytimg.com/vi/nKhAjUGxpmM/hqdefault.jpg The description attributes faster ageing after 75 to zombie cells that an ageing immune system no longer clears, and links shorter telomeres and a shrinking thymus to inflammaging. It then lists senolytics and six self-help levers, from strength training to sleep. https://www.youtube-nocookie.com/embed/nKhAjUGxpmM 1355 2026-09-28T21:00:36.000Z 2026-10-22T21:39:12.472Z https://longevityharbor.com/de/watch/nKhAjUGxpmM Videobeschreibung: Warum der Körper nach 75 schneller altern soll https://i.ytimg.com/vi/nKhAjUGxpmM/hqdefault.jpg Die Beschreibung führt schnelleres Altern nach 75 auf Zombiezellen zurück, die ein alterndes Immunsystem nicht mehr beseitigt, und verbindet kürzere Telomere und einen schrumpfenden Thymus mit Inflammaging. Danach nennt sie Senolytika und sechs Hebel, von Krafttraining bis Schlaf. https://www.youtube-nocookie.com/embed/nKhAjUGxpmM 1355 2026-09-28T21:00:36.000Z 2026-10-22T21:39:12.472Z https://longevityharbor.com/en/watch/nLK9iL7m7aY Mitochondrial Health, Cellular Wellness, and Longevity with Dr. Anurag Singh https://i.ytimg.com/vi/nLK9iL7m7aY/hqdefault.jpg Your body is a trillion-cell Tesla, and your mitochondria are the batteries. What happens when those batteries start to die? Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition, reveals the secrets to recharging your cellular powerhouses for a longer, healthier life. With a background in immunology and internal medicine, Dr. Singh has led studies showing how diet, exercise, and innovative supplements can help maintain mitochondrial function, the “powerhouses” of our cells. In this episode, Dr. Singh explains how mitophagy, a critical process for cellular cleanup, declines as we age. He shares research-backed strategies for keeping cells younger for longer—such as caloric restriction and targeted nutritional products. Listen as Dr. Singh shares what it means to pursue a robust health span, the power of a resilient microbiome, and his vision for a future where we can stay vibrant well into old age. "Think of mitochondria as the battery of your Tesla car...these are like the batteries in our cells that sort of keep us going." ~Dr. Anurag Singh In This Episode: 00:00 - Intro 03:09 - Dr. Singh's journey into mitochondrial health 05:58 - The hallmarks of aging & mitochondrial dysfunction 07:48 - Mitochondria 101: the powerhouse of your cells 11:51 - The mitochondrial life cycle: biogenesis, optimization, and mitophagy 14:50 - Discovering Urolithin A: from pomegranates to patents 18:48 - Clinical trials and real-world applications 21:43 - Caloric restriction vs. Urolithin A 23:51 - Combining Urolithin A with exercise 28:19 - What enhances or impedes Urolithin A production? 34:28 - C-reactive protein and inflammation 37:44 - Wrap-up Q&A About Dr. Anurag Singh: Dr. Anurag Singh is the Chief Medical Officer at Timeline Nutrition, a company developing advanced nutritional and skincare products targeting improvements in mitochondrial and cellular health. He holds an MD in internal medicine and a PhD in immunology. Dr. Singh's research on Urolithin A and its health benefits has led to the launch of multiple https://www.youtube-nocookie.com/embed/nLK9iL7m7aY 2592 2024-11-15T06:00:29.000Z 2026-10-22T19:32:33.393Z https://longevityharbor.com/de/watch/nLK9iL7m7aY Mitochondrial Health, Cellular Wellness, and Longevity with Dr. Anurag Singh https://i.ytimg.com/vi/nLK9iL7m7aY/hqdefault.jpg Your body is a trillion-cell Tesla, and your mitochondria are the batteries. What happens when those batteries start to die? Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition, reveals the secrets to recharging your cellular powerhouses for a longer, healthier life. With a background in immunology and internal medicine, Dr. Singh has led studies showing how diet, exercise, and innovative supplements can help maintain mitochondrial function, the “powerhouses” of our cells. In this episode, Dr. Singh explains how mitophagy, a critical process for cellular cleanup, declines as we age. He shares research-backed strategies for keeping cells younger for longer—such as caloric restriction and targeted nutritional products. Listen as Dr. Singh shares what it means to pursue a robust health span, the power of a resilient microbiome, and his vision for a future where we can stay vibrant well into old age. "Think of mitochondria as the battery of your Tesla car...these are like the batteries in our cells that sort of keep us going." ~Dr. Anurag Singh In This Episode: 00:00 - Intro 03:09 - Dr. Singh's journey into mitochondrial health 05:58 - The hallmarks of aging & mitochondrial dysfunction 07:48 - Mitochondria 101: the powerhouse of your cells 11:51 - The mitochondrial life cycle: biogenesis, optimization, and mitophagy 14:50 - Discovering Urolithin A: from pomegranates to patents 18:48 - Clinical trials and real-world applications 21:43 - Caloric restriction vs. Urolithin A 23:51 - Combining Urolithin A with exercise 28:19 - What enhances or impedes Urolithin A production? 34:28 - C-reactive protein and inflammation 37:44 - Wrap-up Q&A About Dr. Anurag Singh: Dr. Anurag Singh is the Chief Medical Officer at Timeline Nutrition, a company developing advanced nutritional and skincare products targeting improvements in mitochondrial and cellular health. He holds an MD in internal medicine and a PhD in immunology. Dr. Singh's research on Urolithin A and its health benefits has led to the launch of multiple https://www.youtube-nocookie.com/embed/nLK9iL7m7aY 2592 2024-11-15T06:00:29.000Z 2026-10-22T19:32:33.393Z https://longevityharbor.com/en/watch/nLtDc5-DzhE Doctor's video description lists 15 weekly foods and one harmful everyday food https://i.ytimg.com/vi/nLtDc5-DzhE/hqdefault.jpg In the description, UK emergency medicine doctor Dr Alex says he eats 15 single-ingredient foods weekly for longevity, metabolic health and disease prevention, and names one everyday food as harmful; the description gives no study results. https://www.youtube-nocookie.com/embed/nLtDc5-DzhE 2012 2026-01-10T17:43:51.000Z 2026-10-23T02:56:43.480Z https://longevityharbor.com/de/watch/nLtDc5-DzhE Arzt beschreibt im Video 15 wöchentliche Lebensmittel und ein schädliches Alltagslebensmittel https://i.ytimg.com/vi/nLtDc5-DzhE/hqdefault.jpg In der Beschreibung sagt der britische Notfallmediziner Dr Alex, er esse 15 einzelne Lebensmittel wöchentlich für Langlebigkeit, Stoffwechselgesundheit und Krankheitsvorbeugung, und nennt ein Alltagslebensmittel als schädlich; Studienergebnisse enthält die Beschreibung nicht. https://www.youtube-nocookie.com/embed/nLtDc5-DzhE 2012 2026-01-10T17:43:51.000Z 2026-10-23T02:56:43.480Z https://longevityharbor.com/en/watch/nMkQUlBtFlk Dr. Martin Picard on mitochondria, energy and aging in a Huberman Lab description https://i.ytimg.com/vi/nMkQUlBtFlk/hqdefault.jpg In this episode description, Dr. Martin Picard says mitochondria translate behaviors, mindset and relationships into cellular energy, and that lifestyle factors such as exercise, nutrition, sleep and meditation can influence it. The description also says hair greying from cellular stress is reversible. https://www.youtube-nocookie.com/embed/nMkQUlBtFlk 11806 2025-12-15T13:01:43.000Z 2026-10-23T03:16:42.358Z https://longevityharbor.com/de/watch/nMkQUlBtFlk Dr. Martin Picard über Mitochondrien, Energie und Altern in einer Huberman-Lab-Beschreibung https://i.ytimg.com/vi/nMkQUlBtFlk/hqdefault.jpg In dieser Episodenbeschreibung sagt Dr. Martin Picard, Mitochondrien übersetzen Verhalten, Denkweise und Beziehungen in zelluläre Energie, und Lebensstilfaktoren wie Bewegung, Ernährung, Schlaf und Meditation könnten sie beeinflussen. Die Beschreibung nennt außerdem, dass Haargrauwerden durch zellulären Stress umkehrbar sei. https://www.youtube-nocookie.com/embed/nMkQUlBtFlk 11806 2025-12-15T13:01:43.000Z 2026-10-23T03:16:42.358Z https://longevityharbor.com/en/watch/nPWoUFE76_Q Video description: one unnamed ingredient for senior muscle, without exercise https://i.ytimg.com/vi/nPWoUFE76_Q/hqdefault.jpg The description says the video covers one simple ingredient that may support muscle health in seniors, including people who find exercise difficult; the ingredient is never named and no study is described. https://www.youtube-nocookie.com/embed/nPWoUFE76_Q 956 2026-09-24T01:00:05.000Z 2026-10-22T21:55:41.061Z https://longevityharbor.com/de/watch/nPWoUFE76_Q Videobeschreibung: eine ungenannte Zutat für Seniorenmuskeln, ohne Training https://i.ytimg.com/vi/nPWoUFE76_Q/hqdefault.jpg Laut Beschreibung behandelt das Video eine einfache Zutat, die die Muskelgesundheit von Senioren unterstützen könnte, auch bei Menschen, denen Training schwerfällt; die Zutat wird nie genannt und keine Studie beschrieben. https://www.youtube-nocookie.com/embed/nPWoUFE76_Q 956 2026-09-24T01:00:05.000Z 2026-10-22T21:55:41.061Z https://longevityharbor.com/en/watch/nQ70Xw0PNxo Über 60? Diese 5 Übungen sind besser als Spazierengehen – von Ärzten empfohlen! https://i.ytimg.com/vi/nQ70Xw0PNxo/hqdefault.jpg Senioren-Guide: Bewegung, Ernährung & Lebensfreude https://linktr.ee/SeniorenGesundheit Bleiben Sie stark, sicher und beweglich – ganz ohne Fitnessstudio! 💪 In diesem Video zeige ich Ihnen 5 wissenschaftlich belegte Übungen, die speziell für Menschen über 60 entwickelt wurden. Aktuelle Studien aus Kopenhagen, Harvard und Stanford beweisen: ✅ Weniger Trainingszeit – deutlich bessere Ergebnisse. ✅ Bis zu 73 % weniger Sturzrisiko. ✅ 89 % mehr Kraft und mehr Lebensqualität. Diese Übungen helfen bei: • Gelenkschmerzen und Muskelabbau • Gleichgewichtsproblemen und Sturzprävention • besserer Haltung und stärkerem Rücken • mehr Energie und besserer Durchblutung Perfekt geeignet für Senioren, Einsteiger und alle, die sich wieder jünger und sicherer bewegen wollen. Kein teures Equipment – nur wenige Minuten pro Tag! 📅 Empfohlene Routine: 3–4 × pro Woche, jeweils 20–25 Minuten. Abonnieren Sie jetzt den Kanal für weitere Tipps zu Bewegung, Ernährung und gesunder Alterung. 👉 Bleiben Sie aktiv, bleiben Sie unabhängig – in jedem Alter! 👇 Schreiben Sie in die Kommentare: Welche Bewegung fällt Ihnen heute schwerer als früher? #seniorengesundheit #gesundaltern #bewegung #aktivbleiben #seniorhealth #senioren #gesundheit #wohlbefinden #ernährung Disclaimer: Die Videos auf diesem Kanal bieten allgemeine Informationen zur Seniorengesundheit, sind jedoch keine medizinische Beratung. Bei gesundheitlichen Problemen konsultieren Sie bitte immer einen Arzt. Wir übernehmen keine Haftung für die Anwendung der gezeigten Inhalte. https://www.youtube-nocookie.com/embed/nQ70Xw0PNxo 365 2025-10-11T18:05:02.000Z 2026-10-22T17:43:36.110Z https://longevityharbor.com/de/watch/nQ70Xw0PNxo Über 60? Diese 5 Übungen sind besser als Spazierengehen – von Ärzten empfohlen! https://i.ytimg.com/vi/nQ70Xw0PNxo/hqdefault.jpg Senioren-Guide: Bewegung, Ernährung & Lebensfreude https://linktr.ee/SeniorenGesundheit Bleiben Sie stark, sicher und beweglich – ganz ohne Fitnessstudio! 💪 In diesem Video zeige ich Ihnen 5 wissenschaftlich belegte Übungen, die speziell für Menschen über 60 entwickelt wurden. Aktuelle Studien aus Kopenhagen, Harvard und Stanford beweisen: ✅ Weniger Trainingszeit – deutlich bessere Ergebnisse. ✅ Bis zu 73 % weniger Sturzrisiko. ✅ 89 % mehr Kraft und mehr Lebensqualität. Diese Übungen helfen bei: • Gelenkschmerzen und Muskelabbau • Gleichgewichtsproblemen und Sturzprävention • besserer Haltung und stärkerem Rücken • mehr Energie und besserer Durchblutung Perfekt geeignet für Senioren, Einsteiger und alle, die sich wieder jünger und sicherer bewegen wollen. Kein teures Equipment – nur wenige Minuten pro Tag! 📅 Empfohlene Routine: 3–4 × pro Woche, jeweils 20–25 Minuten. Abonnieren Sie jetzt den Kanal für weitere Tipps zu Bewegung, Ernährung und gesunder Alterung. 👉 Bleiben Sie aktiv, bleiben Sie unabhängig – in jedem Alter! 👇 Schreiben Sie in die Kommentare: Welche Bewegung fällt Ihnen heute schwerer als früher? #seniorengesundheit #gesundaltern #bewegung #aktivbleiben #seniorhealth #senioren #gesundheit #wohlbefinden #ernährung Disclaimer: Die Videos auf diesem Kanal bieten allgemeine Informationen zur Seniorengesundheit, sind jedoch keine medizinische Beratung. Bei gesundheitlichen Problemen konsultieren Sie bitte immer einen Arzt. Wir übernehmen keine Haftung für die Anwendung der gezeigten Inhalte. https://www.youtube-nocookie.com/embed/nQ70Xw0PNxo 365 2025-10-11T18:05:02.000Z 2026-10-22T17:43:36.110Z https://longevityharbor.com/en/watch/nVTEBaEJ46I Podcast description: Stanford nutrition researcher discusses food signals, epigenetics and aging https://i.ytimg.com/vi/nVTEBaEJ46I/hqdefault.jpg According to the description, Dr. Lucia Aronica, a Stanford epigenetics scientist and nutrition researcher, tells Mel that food is information that sends signals shaping energy, metabolism, focus and how fast you age. The description lists topics such as weight loss, inflammation, nutrients and gut health. https://www.youtube-nocookie.com/embed/nVTEBaEJ46I 3826 2026-04-30T09:01:17.000Z 2026-10-23T01:19:54.693Z https://longevityharbor.com/de/watch/nVTEBaEJ46I Podcast-Beschreibung: Stanford-Ernährungsforscherin über Ernährungssignale, Epigenetik und Altern https://i.ytimg.com/vi/nVTEBaEJ46I/hqdefault.jpg Laut Beschreibung sagt Dr. Lucia Aronica, Epigenetik-Wissenschaftlerin und Ernährungsforscherin in Stanford, bei Mel, Nahrung sei Information, die Signale sendet und Energie, Stoffwechsel, Konzentration und das Tempo des Alterns prägt. Die Beschreibung nennt Themen wie Gewichtsabnahme, Entzündung, Nährstoffe und Darmgesundheit. https://www.youtube-nocookie.com/embed/nVTEBaEJ46I 3826 2026-04-30T09:01:17.000Z 2026-10-23T01:19:54.693Z https://longevityharbor.com/en/watch/nWhElv6B-T0 Unlock longevity with nmn? #nmn #nad #biohack https://i.ytimg.com/vi/nWhElv6B-T0/hqdefault.jpg Unlock longevity with nmn? #nmn #nad #biohack #energy #fok https://www.youtube-nocookie.com/embed/nWhElv6B-T0 103 2025-03-17T01:34:49.000Z 2026-10-22T19:32:37.742Z https://longevityharbor.com/de/watch/nWhElv6B-T0 Unlock longevity with nmn? #nmn #nad #biohack https://i.ytimg.com/vi/nWhElv6B-T0/hqdefault.jpg Unlock longevity with nmn? #nmn #nad #biohack #energy #fok https://www.youtube-nocookie.com/embed/nWhElv6B-T0 103 2025-03-17T01:34:49.000Z 2026-10-22T19:32:37.742Z https://longevityharbor.com/en/watch/nWyZChKtvII I Took Anti-Aging Pills for 60 Days (NMN) https://i.ytimg.com/vi/nWyZChKtvII/hqdefault.jpg I Took Longevity Pills (NMN) for 60 Days NMN is a supplement that is supposed to increase your NAD levels which has many benefits such as improved metabolism, sleep, energy and many more. I tried the supplement for 60 days to see if I would experience the potential benefits. #longevity #nmn #supplements - The NMN I Took - https://nmnbio.co.uk - MY FITNESS EBOOK - https://peteonpurpose.gumroad.com/l/nomorediets - Get Myriad 3 by Paul Mottram and over 1M + mainstream tracks here https://go.lickd.co/Music License ID: EX2mnkRYOop License ID: qGBn9WRwMdW - Subscribe - https://www.youtube.com/channel/UCGr9jfuQJ3kV-Sdkt9l_LFg?sub_confirmation=1 - Find me on my other socials: 😊 Instagram: https://www.instagram.com/peteonpurpose Tiktok: https://www.tiktok.com/@ptonpurpose E-mail: peteonpurpose@gmail.com - (MY CAMERA GEAR & PRODUCTS I USE) AMAZON SHOP // https://www.amazon.co.uk/shop/peteonpurpose MOBILITY // Pliability App (7-Day Free Trial) https://pliability.com/app/signup?via=pete BAREFOOT SHOES // BAHE (10% off code PETE10) https://bahe.co MUSIC // EPIDEMIC (Free Trial) https://www.epidemicsound.com/referral/hbcwxg/ *Some of the products I earn an affiliate commission, which helps support the channel. I only post affiliate links for products I actually use and endorse myself. https://www.youtube-nocookie.com/embed/nWyZChKtvII 300 2024-01-11T16:56:08.000Z 2026-10-22T18:43:09.940Z https://longevityharbor.com/de/watch/nWyZChKtvII I Took Anti-Aging Pills for 60 Days (NMN) https://i.ytimg.com/vi/nWyZChKtvII/hqdefault.jpg I Took Longevity Pills (NMN) for 60 Days NMN is a supplement that is supposed to increase your NAD levels which has many benefits such as improved metabolism, sleep, energy and many more. I tried the supplement for 60 days to see if I would experience the potential benefits. #longevity #nmn #supplements - The NMN I Took - https://nmnbio.co.uk - MY FITNESS EBOOK - https://peteonpurpose.gumroad.com/l/nomorediets - Get Myriad 3 by Paul Mottram and over 1M + mainstream tracks here https://go.lickd.co/Music License ID: EX2mnkRYOop License ID: qGBn9WRwMdW - Subscribe - https://www.youtube.com/channel/UCGr9jfuQJ3kV-Sdkt9l_LFg?sub_confirmation=1 - Find me on my other socials: 😊 Instagram: https://www.instagram.com/peteonpurpose Tiktok: https://www.tiktok.com/@ptonpurpose E-mail: peteonpurpose@gmail.com - (MY CAMERA GEAR & PRODUCTS I USE) AMAZON SHOP // https://www.amazon.co.uk/shop/peteonpurpose MOBILITY // Pliability App (7-Day Free Trial) https://pliability.com/app/signup?via=pete BAREFOOT SHOES // BAHE (10% off code PETE10) https://bahe.co MUSIC // EPIDEMIC (Free Trial) https://www.epidemicsound.com/referral/hbcwxg/ *Some of the products I earn an affiliate commission, which helps support the channel. I only post affiliate links for products I actually use and endorse myself. https://www.youtube-nocookie.com/embed/nWyZChKtvII 300 2024-01-11T16:56:08.000Z 2026-10-22T18:43:09.940Z https://longevityharbor.com/en/watch/nXFQnhcqpbs Video description: equal diets, different needs claimed by iPro https://i.ytimg.com/vi/nXFQnhcqpbs/hqdefault.jpg The description argues that two people eating the same healthy food can still differ in individual nutrient needs because sleep, time outdoors and stress differ; it then points to iPro body analysis. https://www.youtube-nocookie.com/embed/nXFQnhcqpbs 141 2026-09-18T05:00:17.000Z 2026-10-22T22:05:11.375Z https://longevityharbor.com/de/watch/nXFQnhcqpbs Videobeschreibung: gleiche Ernährung, unterschiedlicher Bedarf laut iPro https://i.ytimg.com/vi/nXFQnhcqpbs/hqdefault.jpg Die Beschreibung argumentiert, dass zwei Menschen trotz gleicher gesunder Ernährung unterschiedlichen individuellen Nährstoffbedarf haben können, weil Schlaf, Zeit draußen und Stress sich unterscheiden; anschließend verweist sie auf die iPro Körperanalyse. https://www.youtube-nocookie.com/embed/nXFQnhcqpbs 141 2026-09-18T05:00:17.000Z 2026-10-22T22:05:11.375Z https://longevityharbor.com/en/watch/nYLypwZ_KO0 The Only 5 Exercises You Need After 70 to Reverse Aging | Feynman Explained https://i.ytimg.com/vi/nYLypwZ_KO0/hqdefault.jpg The Only 5 Exercises You Need After 70 to Reverse Aging | Feynman Explained Did you know that the number of times you can rise from a chair in thirty seconds predicts your risk of losing independence better than your age does—and that muscle power declines roughly three times faster than muscle strength after sixty? Most people after seventy are not losing muscle so much as losing the ability to use it quickly, and that speed is what keeps you on your feet when a slip happens. Five patterns—push, pull, squat, step, and calf—cover nearly every movement of daily life, and they fit in eighteen minutes, twice a week, with no gym. In this video, you'll learn what actually changes after seventy, why fast, controlled effort beats heavy slow lifting, and how the chair rise test can give you an objective baseline tonight. We'll walk through the five movements one by one, explain why the lowering half of each repetition matters as much as the push, and lay out a simple twelve-week protocol you can run at home with a chair, a wall, a band, and one step. In this video, you'll discover: How the thirty-second chair rise test predicts falls and independence better than age Why muscle power drops about three times faster than strength after sixty How five movement patterns—push, pull, squat, step, calf—cover your entire day Why every repetition should start fast and end with a slow, controlled lowering How one-leg training exposes and fixes the strength gap that causes most falls Why two sessions a week and eighteen minutes each is the whole prescription How walking speed works as the sixth vital sign, and what number to watch A twelve-week plan you can start tonight with equipment you already own Whether you're trying to protect your balance, keep climbing your own stairs, stay independent, or simply understand what your body is really losing after seventy, this video walks you through the science in plain, evidence-first language. If you enjoy science-based health content explained simply, Like, Subscribe, and turn on no https://www.youtube-nocookie.com/embed/nYLypwZ_KO0 1041 2026-09-21T12:56:12.000Z 2026-10-22T19:21:29.578Z https://longevityharbor.com/de/watch/nYLypwZ_KO0 The Only 5 Exercises You Need After 70 to Reverse Aging | Feynman Explained https://i.ytimg.com/vi/nYLypwZ_KO0/hqdefault.jpg The Only 5 Exercises You Need After 70 to Reverse Aging | Feynman Explained Did you know that the number of times you can rise from a chair in thirty seconds predicts your risk of losing independence better than your age does—and that muscle power declines roughly three times faster than muscle strength after sixty? Most people after seventy are not losing muscle so much as losing the ability to use it quickly, and that speed is what keeps you on your feet when a slip happens. Five patterns—push, pull, squat, step, and calf—cover nearly every movement of daily life, and they fit in eighteen minutes, twice a week, with no gym. In this video, you'll learn what actually changes after seventy, why fast, controlled effort beats heavy slow lifting, and how the chair rise test can give you an objective baseline tonight. We'll walk through the five movements one by one, explain why the lowering half of each repetition matters as much as the push, and lay out a simple twelve-week protocol you can run at home with a chair, a wall, a band, and one step. In this video, you'll discover: How the thirty-second chair rise test predicts falls and independence better than age Why muscle power drops about three times faster than strength after sixty How five movement patterns—push, pull, squat, step, calf—cover your entire day Why every repetition should start fast and end with a slow, controlled lowering How one-leg training exposes and fixes the strength gap that causes most falls Why two sessions a week and eighteen minutes each is the whole prescription How walking speed works as the sixth vital sign, and what number to watch A twelve-week plan you can start tonight with equipment you already own Whether you're trying to protect your balance, keep climbing your own stairs, stay independent, or simply understand what your body is really losing after seventy, this video walks you through the science in plain, evidence-first language. If you enjoy science-based health content explained simply, Like, Subscribe, and turn on no https://www.youtube-nocookie.com/embed/nYLypwZ_KO0 1041 2026-09-21T12:56:12.000Z 2026-10-22T19:21:29.578Z https://longevityharbor.com/en/watch/nZfOGLklnBM Why Longevity Experts Are Warning Against Fasting https://i.ytimg.com/vi/nZfOGLklnBM/hqdefault.jpg Why have Peter Attia and Rhonda Patrick, who are both famous doctors in the longevity space, changed their position on fasting? And how should we approach fasting, based on the latest human research, to optimize our health? For weekly health research summaries and extra sights, sign up here 👉 https://drstanfield.com/pages/sign-up 📜 Roadmap - how to look young & feel strong: https://drstanfield.com/pages/roadmap ✔️ Twitter: https://twitter.com/BradStanfieldMD ✔️ Patreon: https://www.patreon.com/bradstanfieldmd Here are the links to the research papers referenced in the video: https://www.youtube.com/watch?v=Si6CGiU62V0&ab_channel=PeterAttiaMD https://www.youtube.com/watch?v=pRM7mler8KQ&ab_channel=ThomasDeLauer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627766/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990190/ https://pubmed.ncbi.nlm.nih.gov/31808043/ https://iris.unito.it/retrieve/handle/2318/1739566/635675/Bo%20et%20al%20Revised.pdf https://www.cochrane.org/CD013496/VASC_does-limiting-times-you-eat-intermittent-fasting-prevent-cardiovascular-disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138754/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024204/ https://pubmed.ncbi.nlm.nih.gov/38639542/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867436/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355425/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151159/ Video edited by Troy Young The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel. https://www.youtube-nocookie.com/embed/nZfOGLklnBM 540 2024-08-07T19:56:31.000Z 2026-10-22T17:43:38.408Z https://longevityharbor.com/de/watch/nZfOGLklnBM Why Longevity Experts Are Warning Against Fasting https://i.ytimg.com/vi/nZfOGLklnBM/hqdefault.jpg Why have Peter Attia and Rhonda Patrick, who are both famous doctors in the longevity space, changed their position on fasting? And how should we approach fasting, based on the latest human research, to optimize our health? For weekly health research summaries and extra sights, sign up here 👉 https://drstanfield.com/pages/sign-up 📜 Roadmap - how to look young & feel strong: https://drstanfield.com/pages/roadmap ✔️ Twitter: https://twitter.com/BradStanfieldMD ✔️ Patreon: https://www.patreon.com/bradstanfieldmd Here are the links to the research papers referenced in the video: https://www.youtube.com/watch?v=Si6CGiU62V0&ab_channel=PeterAttiaMD https://www.youtube.com/watch?v=pRM7mler8KQ&ab_channel=ThomasDeLauer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627766/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990190/ https://pubmed.ncbi.nlm.nih.gov/31808043/ https://iris.unito.it/retrieve/handle/2318/1739566/635675/Bo%20et%20al%20Revised.pdf https://www.cochrane.org/CD013496/VASC_does-limiting-times-you-eat-intermittent-fasting-prevent-cardiovascular-disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138754/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024204/ https://pubmed.ncbi.nlm.nih.gov/38639542/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867436/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355425/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151159/ Video edited by Troy Young The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel. https://www.youtube-nocookie.com/embed/nZfOGLklnBM 540 2024-08-07T19:56:31.000Z 2026-10-22T17:43:38.408Z https://longevityharbor.com/en/watch/nirCmIrGcyE Episode 11 - Exercise and Healthy Aging https://i.ytimg.com/vi/nirCmIrGcyE/hqdefault.jpg Exercise is beneficial for older adults. Those who are physically active report better overall health, lower health care expenditures, and fewer mobility limitations than their sedentary counterparts. This episode features Cathty Turner, Director, Health Promotion and Senior Health, Virginia Hospital Center, who explains why physical activity is a vital part of healthy aging and demonstrates simple exercises older adults can do at home to stay well and improve quality of life. https://www.youtube-nocookie.com/embed/nirCmIrGcyE 1776 2019-08-14T12:54:33.000Z 2026-10-22T19:02:25.499Z https://longevityharbor.com/de/watch/nirCmIrGcyE Episode 11 - Exercise and Healthy Aging https://i.ytimg.com/vi/nirCmIrGcyE/hqdefault.jpg Exercise is beneficial for older adults. Those who are physically active report better overall health, lower health care expenditures, and fewer mobility limitations than their sedentary counterparts. This episode features Cathty Turner, Director, Health Promotion and Senior Health, Virginia Hospital Center, who explains why physical activity is a vital part of healthy aging and demonstrates simple exercises older adults can do at home to stay well and improve quality of life. https://www.youtube-nocookie.com/embed/nirCmIrGcyE 1776 2019-08-14T12:54:33.000Z 2026-10-22T19:02:25.499Z https://longevityharbor.com/en/watch/njWE3Fuu6k8 Warum gerade jeder NMN nimmt... https://i.ytimg.com/vi/njWE3Fuu6k8/hqdefault.jpg beLIVELY NMN - jetzt verfügbar! https://we-are-lively.com/products/nmn-nad-booster Longevity - Made in Germany. https://www.youtube-nocookie.com/embed/njWE3Fuu6k8 119 2026-06-09T20:27:00.000Z 2026-10-22T20:11:47.165Z https://longevityharbor.com/de/watch/njWE3Fuu6k8 Warum gerade jeder NMN nimmt... https://i.ytimg.com/vi/njWE3Fuu6k8/hqdefault.jpg beLIVELY NMN - jetzt verfügbar! https://we-are-lively.com/products/nmn-nad-booster Longevity - Made in Germany. https://www.youtube-nocookie.com/embed/njWE3Fuu6k8 119 2026-06-09T20:27:00.000Z 2026-10-22T20:11:47.165Z https://longevityharbor.com/en/watch/njmWpNJapRc 🧬 NMN: The Anti-Aging Molecule Science Can't Stop Talking About (Dr David Sinclair) https://i.ytimg.com/vi/njmWpNJapRc/hqdefault.jpg NMN: The Anti-Aging Molecule Science Can't Stop Talking About GET YOUR NMN ➡️https://shopsolensis.com/products/nmn-nicotinamide-mononucleotide-15-grams In 2018, the WHO officially classified aging as a disease—opening the door to treatments that could extend human healthspan. At the center of this longevity revolution is NMN (Nicotinamide Mononucleotide), a precursor to NAD+ that may hold the key to reversing cellular aging. In this video, we break down: ✅ Why NAD+ decline drives every hallmark of aging ✅ How NMN restores NAD+ levels and cellular function ✅ The breakthrough Slc12a8 transporter discovery ✅ Comprehensive benefits seen in preclinical studies ✅ What leading Harvard and Washington University researchers say ✅ Safety, absorption, and bioavailability data ✅ The future of liposomal delivery systems Featuring insights from Dr. David Sinclair (Harvard) and Dr. Shin-ichiro Imai (Washington University), this is your complete guide to understanding NMN and NAD+ biology. ⏱️ VIDEO CHAPTERS: 0:00 - 2018 Changed Everything 0:29 - Introduction: The NAD+ Network 1:03 - NAD+ Decline Drives All Aging Hallmarks 1:38 - The Dramatic NAD+ Collapse 2:05 - The Solution: NMN as NAD+ Precursor 2:49 - How Your Body Synthesizes NMN 3:33 - Breakthrough: Direct Cellular Transport 4:18 - Why Supplementation Is Necessary 4:55 - Remarkable Preclinical Results 5:29 - Comprehensive Catalog of Benefits 6:20 - Practical Profile: Stability & Safety 6:56 - Translation to Human Health 7:15 - What Leading Experts Say 7:49 - Conclusion: The Future of Aging Disclaimer: The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel. All materials in these videos are used for educational purposes and fall within the guidelines of fair use. No copyright infringement intended. If you are or https://www.youtube-nocookie.com/embed/njmWpNJapRc 517 2026-01-14T19:53:05.000Z 2026-10-22T18:32:10.823Z https://longevityharbor.com/de/watch/njmWpNJapRc 🧬 NMN: The Anti-Aging Molecule Science Can't Stop Talking About (Dr David Sinclair) https://i.ytimg.com/vi/njmWpNJapRc/hqdefault.jpg NMN: The Anti-Aging Molecule Science Can't Stop Talking About GET YOUR NMN ➡️https://shopsolensis.com/products/nmn-nicotinamide-mononucleotide-15-grams In 2018, the WHO officially classified aging as a disease—opening the door to treatments that could extend human healthspan. At the center of this longevity revolution is NMN (Nicotinamide Mononucleotide), a precursor to NAD+ that may hold the key to reversing cellular aging. In this video, we break down: ✅ Why NAD+ decline drives every hallmark of aging ✅ How NMN restores NAD+ levels and cellular function ✅ The breakthrough Slc12a8 transporter discovery ✅ Comprehensive benefits seen in preclinical studies ✅ What leading Harvard and Washington University researchers say ✅ Safety, absorption, and bioavailability data ✅ The future of liposomal delivery systems Featuring insights from Dr. David Sinclair (Harvard) and Dr. Shin-ichiro Imai (Washington University), this is your complete guide to understanding NMN and NAD+ biology. ⏱️ VIDEO CHAPTERS: 0:00 - 2018 Changed Everything 0:29 - Introduction: The NAD+ Network 1:03 - NAD+ Decline Drives All Aging Hallmarks 1:38 - The Dramatic NAD+ Collapse 2:05 - The Solution: NMN as NAD+ Precursor 2:49 - How Your Body Synthesizes NMN 3:33 - Breakthrough: Direct Cellular Transport 4:18 - Why Supplementation Is Necessary 4:55 - Remarkable Preclinical Results 5:29 - Comprehensive Catalog of Benefits 6:20 - Practical Profile: Stability & Safety 6:56 - Translation to Human Health 7:15 - What Leading Experts Say 7:49 - Conclusion: The Future of Aging Disclaimer: The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel. All materials in these videos are used for educational purposes and fall within the guidelines of fair use. No copyright infringement intended. If you are or https://www.youtube-nocookie.com/embed/njmWpNJapRc 517 2026-01-14T19:53:05.000Z 2026-10-22T18:32:10.823Z https://longevityharbor.com/en/watch/nmXrhl54wpI Rapamycin in mice and other effects outside of longevity | Peter Attia & Rich Miller https://i.ytimg.com/vi/nmXrhl54wpI/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/sZ-krUa6VH0 Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from 281 Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program (ITP) with Rich Miller, M.D., Ph.D. In this clip, Peter and Rich discuss: - The success of rapamycin as a longevity drug - Sex-specific differences in longevity drug tests - Potential issues with drug dose recommendations between men and women - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical https://www.youtube-nocookie.com/embed/nmXrhl54wpI 817 2023-12-06T17:00:45.000Z 2026-10-22T19:54:21.188Z https://longevityharbor.com/de/watch/nmXrhl54wpI Rapamycin in mice and other effects outside of longevity | Peter Attia & Rich Miller https://i.ytimg.com/vi/nmXrhl54wpI/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/sZ-krUa6VH0 Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from 281 Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program (ITP) with Rich Miller, M.D., Ph.D. In this clip, Peter and Rich discuss: - The success of rapamycin as a longevity drug - Sex-specific differences in longevity drug tests - Potential issues with drug dose recommendations between men and women - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical https://www.youtube-nocookie.com/embed/nmXrhl54wpI 817 2023-12-06T17:00:45.000Z 2026-10-22T19:54:21.188Z https://longevityharbor.com/en/watch/ntdRFgWWeUA How do Senolytics Work to Target Senescent Cells | Dr. James Kirkland https://i.ytimg.com/vi/ntdRFgWWeUA/hqdefault.jpg Do you know what senescent (zombie) cells are and how cellular senescence and senolytics impact health? This clip is from an episode of Longevity by Design; Hosts Ashley Reaver and Dr. Gil Blander are joined by Dr. James Kirkland from the Mayo Clinic, one of the world's leading figures in aging research. The episode is a deep dive into aging research, cellular senescence, and senolytics. Dr. Kirkland discusses the impact of cellular aging (senescence) on healthspan and his discovery of the first senolytic agents that remove senescent cells and extend healthspan, illuminating his pioneering work in aging research. In the full discussion, we cover: What is geroscience, and what are fundamental aging processes? What are the differences between targeting aging vs. the traditional medical system of waiting to treat illnesses or diseases after they occur? What are gerotherapeutics, and what is their relevance for healthspan and lifespan?: What are senescent cells? What is the impact of senescent cells on the body and aging: What are senolytics? How do senolytics work to target senescent cells to remove them? How Dr. James Kirkland discovered senolytics such as fisetin, quercetin, and dasatinib? What clinical trials on the effects of senolytics in humans have been done? Discovering biomarkers for senescent cells: What are some important factors to consider on the effects of gerotherapeutics and senolytics on lifespan and healthspan in model organisms compared to humans?: The potential for geroscience and gerotherapeutics, such as senolytics, to transform healthcare. What is the importance and what are some challenges of conducting clinical trials on gerotherapeutics, such as senolytics, to improve healthspan in humans? What is the Translational Geroscience Network, and what are its goals? How might senolytics be used clinically in the future if proven safe and effective? What conditions might they benefit? What are the effects of lifestyle, such as diet and exercise, on senescent cells? What excites Dr. James K https://www.youtube-nocookie.com/embed/ntdRFgWWeUA 476 2024-04-30T20:57:12.000Z 2026-10-22T18:43:13.652Z https://longevityharbor.com/de/watch/ntdRFgWWeUA How do Senolytics Work to Target Senescent Cells | Dr. James Kirkland https://i.ytimg.com/vi/ntdRFgWWeUA/hqdefault.jpg Do you know what senescent (zombie) cells are and how cellular senescence and senolytics impact health? This clip is from an episode of Longevity by Design; Hosts Ashley Reaver and Dr. Gil Blander are joined by Dr. James Kirkland from the Mayo Clinic, one of the world's leading figures in aging research. The episode is a deep dive into aging research, cellular senescence, and senolytics. Dr. Kirkland discusses the impact of cellular aging (senescence) on healthspan and his discovery of the first senolytic agents that remove senescent cells and extend healthspan, illuminating his pioneering work in aging research. In the full discussion, we cover: What is geroscience, and what are fundamental aging processes? What are the differences between targeting aging vs. the traditional medical system of waiting to treat illnesses or diseases after they occur? What are gerotherapeutics, and what is their relevance for healthspan and lifespan?: What are senescent cells? What is the impact of senescent cells on the body and aging: What are senolytics? How do senolytics work to target senescent cells to remove them? How Dr. James Kirkland discovered senolytics such as fisetin, quercetin, and dasatinib? What clinical trials on the effects of senolytics in humans have been done? Discovering biomarkers for senescent cells: What are some important factors to consider on the effects of gerotherapeutics and senolytics on lifespan and healthspan in model organisms compared to humans?: The potential for geroscience and gerotherapeutics, such as senolytics, to transform healthcare. What is the importance and what are some challenges of conducting clinical trials on gerotherapeutics, such as senolytics, to improve healthspan in humans? What is the Translational Geroscience Network, and what are its goals? How might senolytics be used clinically in the future if proven safe and effective? What conditions might they benefit? What are the effects of lifestyle, such as diet and exercise, on senescent cells? What excites Dr. James K https://www.youtube-nocookie.com/embed/ntdRFgWWeUA 476 2024-04-30T20:57:12.000Z 2026-10-22T18:43:13.652Z https://longevityharbor.com/en/watch/ntzDC2RIUYM Video description: five foods discussed for sleep and memory after 60 https://i.ytimg.com/vi/ntzDC2RIUYM/hqdefault.jpg A video description lists kiwi, tart cherries, pumpkin seeds, leafy greens and blueberries as foods discussed for sleep and brain health after 60, and stresses that sleep habits, caffeine, alcohol, activity, diet, medications and health conditions also matter. https://www.youtube-nocookie.com/embed/ntzDC2RIUYM 1306 2026-10-20T13:00:10.000Z 2026-10-22T19:49:28.393Z https://longevityharbor.com/de/watch/ntzDC2RIUYM Videobeschreibung: fünf Lebensmittel zu Schlaf und Gedächtnis ab 60 https://i.ytimg.com/vi/ntzDC2RIUYM/hqdefault.jpg Eine Videobeschreibung nennt Kiwi, Sauerkirschen, Kürbiskerne, Blattgemüse und Heidelbeeren als Lebensmittel, die für Schlaf und Gehirngesundheit ab 60 diskutiert werden, und betont, dass auch Schlafgewohnheiten, Koffein, Alkohol, Bewegung, Ernährung, Medikamente und Gesundheitszustand zählen. https://www.youtube-nocookie.com/embed/ntzDC2RIUYM 1306 2026-10-20T13:00:10.000Z 2026-10-22T19:49:28.393Z https://longevityharbor.com/en/watch/nwdu6iS9bsE Top 5 Things To Do in Your 50s for Longevity https://i.ytimg.com/vi/nwdu6iS9bsE/hqdefault.jpg Are you in your 50s and wondering how to optimize your health for the decades ahead? Discover Dr. Josh Axe's top 5 strategies for thriving in your golden years! In this essential episode of The Dr. Josh Axe Show, learn how to combat the most common health challenges facing adults over 50. With nearly half of adults aged 45-64 battling hypertension and 24% struggling with arthritis, it's crucial to take proactive steps now for a healthier future. Key takeaways from this episode: * Shocking statistics on chronic conditions affecting adults 50+ and how to prevent them * Essential vitamins and supplements tailored for men and women in their 50s * Why one daily activity could slash your mortality risk by 51% * Best diet for supporting heart health and cognitive function * How to navigate common life challenges like empty nest syndrome and caring for aging parents * The importance of staying socially connected and finding purpose in your 50s and beyond Tune in to arm yourself with practical, evidence-based advice for extending your health span and improving your quality of life. Whether you're battling chronic conditions, facing hormonal changes, or simply want to age gracefully, this episode offers invaluable insights to help you thrive in your 50s and beyond. Don't miss this opportunity to take control of your health and set the stage for a vibrant, active future! #antiaging #longevity #fifty #50 #midlifecrisis -------------------- Links: Customize a plan for yourself by working with a functional medicine practitioner. Go to AxeWellness.com https://supplementfirst.com/blogs/supplement-first-healthy-living/common-nutrient-deficiencies-in-people-over-50 https://www.rwjbh.org/blog/2019/august/the-healthy-benefits-of-antioxidants/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912123/ https://news.llu.edu/health-wellness/common-vitamin-deficiencies-women-effects-aging-and-weight-loss#:~:text=Women%20have%20different%20nutritional%20needs,and%20calcium%20even%20more%20critical. https://www.hopkinsmedicine.org https://www.youtube-nocookie.com/embed/nwdu6iS9bsE 2029 2024-07-02T16:00:44.000Z 2026-10-22T19:04:44.845Z https://longevityharbor.com/de/watch/nwdu6iS9bsE Top 5 Things To Do in Your 50s for Longevity https://i.ytimg.com/vi/nwdu6iS9bsE/hqdefault.jpg Are you in your 50s and wondering how to optimize your health for the decades ahead? Discover Dr. Josh Axe's top 5 strategies for thriving in your golden years! In this essential episode of The Dr. Josh Axe Show, learn how to combat the most common health challenges facing adults over 50. With nearly half of adults aged 45-64 battling hypertension and 24% struggling with arthritis, it's crucial to take proactive steps now for a healthier future. Key takeaways from this episode: * Shocking statistics on chronic conditions affecting adults 50+ and how to prevent them * Essential vitamins and supplements tailored for men and women in their 50s * Why one daily activity could slash your mortality risk by 51% * Best diet for supporting heart health and cognitive function * How to navigate common life challenges like empty nest syndrome and caring for aging parents * The importance of staying socially connected and finding purpose in your 50s and beyond Tune in to arm yourself with practical, evidence-based advice for extending your health span and improving your quality of life. Whether you're battling chronic conditions, facing hormonal changes, or simply want to age gracefully, this episode offers invaluable insights to help you thrive in your 50s and beyond. Don't miss this opportunity to take control of your health and set the stage for a vibrant, active future! #antiaging #longevity #fifty #50 #midlifecrisis -------------------- Links: Customize a plan for yourself by working with a functional medicine practitioner. Go to AxeWellness.com https://supplementfirst.com/blogs/supplement-first-healthy-living/common-nutrient-deficiencies-in-people-over-50 https://www.rwjbh.org/blog/2019/august/the-healthy-benefits-of-antioxidants/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912123/ https://news.llu.edu/health-wellness/common-vitamin-deficiencies-women-effects-aging-and-weight-loss#:~:text=Women%20have%20different%20nutritional%20needs,and%20calcium%20even%20more%20critical. https://www.hopkinsmedicine.org https://www.youtube-nocookie.com/embed/nwdu6iS9bsE 2029 2024-07-02T16:00:44.000Z 2026-10-22T19:04:44.845Z https://longevityharbor.com/en/watch/nwhudYwSS6Y Gesunde Ernährung? Klar! Was sie dir bei Hämophilie bringt, erfährst du in dieser Aufzeichnung. https://i.ytimg.com/vi/nwhudYwSS6Y/hqdefault.jpg Ernährung bei Hämophilie. Was tut dir gut? Ein Special für Menschen mit Gerinnungsstörungen. Unsere Experten räumen mit Mythen auf, erklären die Basics ausgewogener Ernährung und beantworten deine Fragen: - Wie viele Proteine brauche ich für den Muskelaufbau? - Welche Folgen hat falsche Ernährung im höheren Alter? - Worauf muss ich bei Diäten achten? Special Guest Prof. Dr. med. Irina Blumenstein Fachärztin für Innere Medizin, Schwerpunkte Gastroenterologie, Ernährungsmedizin, Universitätsmedizin Frankfurt/Main Dr. med. Georg Goldmann Facharzt für Transfusionsmedizin und Hämostaseologie, Oberarzt im Institut für Experimentelle Hämatologie und Transfusionsmedizin (IHT), Universitätsklinikum Bonn PD Dr. Dr. med. Christoph Königs Facharzt für Kinder- und Jugendmedizin, Universitätsklinikum Frankfurt, Gerinnungszentrum PD Dr. Christian Pfrepper Facharzt für Innere Medizin, Hämatologie, Onkologie und Hämostaseologie, Oberarzt der Gerinnungsambulanz, Universitätsklinikum Leipzig Moderation durch die Patientenorganisationen https://www.youtube-nocookie.com/embed/nwhudYwSS6Y 3664 2025-05-21T18:00:48.000Z 2026-10-22T20:11:49.338Z https://longevityharbor.com/de/watch/nwhudYwSS6Y Gesunde Ernährung? Klar! Was sie dir bei Hämophilie bringt, erfährst du in dieser Aufzeichnung. https://i.ytimg.com/vi/nwhudYwSS6Y/hqdefault.jpg Ernährung bei Hämophilie. Was tut dir gut? Ein Special für Menschen mit Gerinnungsstörungen. Unsere Experten räumen mit Mythen auf, erklären die Basics ausgewogener Ernährung und beantworten deine Fragen: - Wie viele Proteine brauche ich für den Muskelaufbau? - Welche Folgen hat falsche Ernährung im höheren Alter? - Worauf muss ich bei Diäten achten? Special Guest Prof. Dr. med. Irina Blumenstein Fachärztin für Innere Medizin, Schwerpunkte Gastroenterologie, Ernährungsmedizin, Universitätsmedizin Frankfurt/Main Dr. med. Georg Goldmann Facharzt für Transfusionsmedizin und Hämostaseologie, Oberarzt im Institut für Experimentelle Hämatologie und Transfusionsmedizin (IHT), Universitätsklinikum Bonn PD Dr. Dr. med. Christoph Königs Facharzt für Kinder- und Jugendmedizin, Universitätsklinikum Frankfurt, Gerinnungszentrum PD Dr. Christian Pfrepper Facharzt für Innere Medizin, Hämatologie, Onkologie und Hämostaseologie, Oberarzt der Gerinnungsambulanz, Universitätsklinikum Leipzig Moderation durch die Patientenorganisationen https://www.youtube-nocookie.com/embed/nwhudYwSS6Y 3664 2025-05-21T18:00:48.000Z 2026-10-22T20:11:49.338Z https://longevityharbor.com/en/watch/nwnCMdT9nNk Gesund alt werden - Was steckt hinter Longevity? https://i.ytimg.com/vi/nwnCMdT9nNk/hqdefault.jpg Longevity ist in aller Munde. Dr. Lüscher geht auf den Trend der Langlebigkeit ein und erklärt, wie man länger und besser leben kann. Der Alterungsprozess wird primär von der Gesundheitsspanne beeinflusst. Chronische Krankheiten spielen dabei eine wichtige Rolle. Im Durchschnitt sind wir, bevor wir sterben, 26 Jahre lang krank. Dr. Lüscher erläutert den Prozess der Seneszenz und das Problem, dass alte seneszente Zellen nicht abgebaut werden. Das eigene Immunsystem baut diese Zellen in jungen Jahren ganz einfach ab. Im Alter jedoch häufen sich diese Zellen an. Wir können den Körper bei der Senolyse mit Produkten wie Senofree unterstützen. Dieses ist in der Lage, alte Zellen zu markieren und das Immunsystem beim Abbau zu unterstützen. Danach müssen aber wieder neue, funktionsfähige Zellen aufgebaut werden. SenoXure unterstützt den Körper dabei, die abgebauten Zellen zu erneuern. Bei der Einnahme wechselt man jeweils ab: Für einen Monat baut man alte Zellen ab, im nächsten Monat baut man neue auf. Dies kann man einige Male wiederholen und so den Alterungsprozess des Körpers positiv beeinflussen. Mehr Informationen zu Longevity: https://longevity-advice.com/ Mehr zum Thema Senolytika: ⭐️ https://www.vitalstoffmedizin.ch/wirkstoff/der-zellalterung-entgegenwirken-mit-senolytika-und-senorevertika/ Mehr Informationen zu Vitalstoffmedizin unter: ⭐️ https://vitalstoffmedizin.ch ⭐️ https://integrative-medicine.info 00:00 Intro 00:25 Was bedeutet Longevity? 02:00 Alterungsprozess und Gesundheitsspanne 03:30 Seneszenz der Grund für die Zellalterung 05:30 Senolyse mit SenoFree 06:00 Wachstum neuer Zellen unterstützen 07:00 Anwendung von Longevity Produkten #vitalstoffe #vitalstoffmedizin #longevity #SenoFree #SenoXure 97 https://www.youtube-nocookie.com/embed/nwnCMdT9nNk 441 2025-02-25T15:01:11.000Z 2026-10-22T18:43:12.567Z https://longevityharbor.com/de/watch/nwnCMdT9nNk Gesund alt werden - Was steckt hinter Longevity? https://i.ytimg.com/vi/nwnCMdT9nNk/hqdefault.jpg Longevity ist in aller Munde. Dr. Lüscher geht auf den Trend der Langlebigkeit ein und erklärt, wie man länger und besser leben kann. Der Alterungsprozess wird primär von der Gesundheitsspanne beeinflusst. Chronische Krankheiten spielen dabei eine wichtige Rolle. Im Durchschnitt sind wir, bevor wir sterben, 26 Jahre lang krank. Dr. Lüscher erläutert den Prozess der Seneszenz und das Problem, dass alte seneszente Zellen nicht abgebaut werden. Das eigene Immunsystem baut diese Zellen in jungen Jahren ganz einfach ab. Im Alter jedoch häufen sich diese Zellen an. Wir können den Körper bei der Senolyse mit Produkten wie Senofree unterstützen. Dieses ist in der Lage, alte Zellen zu markieren und das Immunsystem beim Abbau zu unterstützen. Danach müssen aber wieder neue, funktionsfähige Zellen aufgebaut werden. SenoXure unterstützt den Körper dabei, die abgebauten Zellen zu erneuern. Bei der Einnahme wechselt man jeweils ab: Für einen Monat baut man alte Zellen ab, im nächsten Monat baut man neue auf. Dies kann man einige Male wiederholen und so den Alterungsprozess des Körpers positiv beeinflussen. Mehr Informationen zu Longevity: https://longevity-advice.com/ Mehr zum Thema Senolytika: ⭐️ https://www.vitalstoffmedizin.ch/wirkstoff/der-zellalterung-entgegenwirken-mit-senolytika-und-senorevertika/ Mehr Informationen zu Vitalstoffmedizin unter: ⭐️ https://vitalstoffmedizin.ch ⭐️ https://integrative-medicine.info 00:00 Intro 00:25 Was bedeutet Longevity? 02:00 Alterungsprozess und Gesundheitsspanne 03:30 Seneszenz der Grund für die Zellalterung 05:30 Senolyse mit SenoFree 06:00 Wachstum neuer Zellen unterstützen 07:00 Anwendung von Longevity Produkten #vitalstoffe #vitalstoffmedizin #longevity #SenoFree #SenoXure 97 https://www.youtube-nocookie.com/embed/nwnCMdT9nNk 441 2025-02-25T15:01:11.000Z 2026-10-22T18:43:12.567Z https://longevityharbor.com/en/watch/o2_HMHrKo3g Humans at 150: How Epigenetic Clocks Could Transform Longevity https://i.ytimg.com/vi/o2_HMHrKo3g/hqdefault.jpg #beyondtomorrow #futurology https://www.youtube-nocookie.com/embed/o2_HMHrKo3g 233 2026-03-06T16:01:21.000Z 2026-10-22T19:21:27.764Z https://longevityharbor.com/de/watch/o2_HMHrKo3g Humans at 150: How Epigenetic Clocks Could Transform Longevity https://i.ytimg.com/vi/o2_HMHrKo3g/hqdefault.jpg #beyondtomorrow #futurology https://www.youtube-nocookie.com/embed/o2_HMHrKo3g 233 2026-03-06T16:01:21.000Z 2026-10-22T19:21:27.764Z https://longevityharbor.com/en/watch/o6D8hXayG9M NMN Vs NR For Longevity | Comparing NAD Booster Supplements https://i.ytimg.com/vi/o6D8hXayG9M/hqdefault.jpg NMN and NR are both NAD boosters...so which is better? In this video I will discuss the difference between NAD, NMN and NR, explaining how they work to increase lifespan and improve your overall health. Free Gift: Guide for the 5 best supplements you can take: https://bit.ly/3CaLQCM NAD stands Nicotinamide Adenine Dinucleotide and its important in your mitochondria, helping you convert food into energy. NAD is also important for maintaining your DNA to protect you from ageing and disease. Unfortunately, your levels of NAD naturally decline as you get older Nicotinamide MonoNucleotide (NMN) is a precursor of NAD, & Nicotinamide Riboside (NR) is a precursor of NMN You can take both NMN and NR orally and they both move into your bloodstream and get taken up into all of your cells. NR is nice and small, so it gets taken up into your cells via a transporter, but NMN is medium sized and sometimes it can be taken up your cells...but sometimes it needs to be broken down into NR before it can move into your cells. ANYWAY, once it’s in the cell, NR turns into NMN, NMN turns into NAD, and NAD works to make more energy and it also activates sirtuins, which slow down the ageing process. Studies have shown that Yeast strains can live 30% longer when given NR, and mice have been shown to live 9% longer when given NR. Those mice also had more energy, less inflammation, and were generally healthier than the mice that didn’t receive NR NMN vs NR Website https://www.nmn.com/precursors/nmn-vs-nr Sirtuins and NAD boosters https://www.nature.com/articles/nrm.2016.93 2018 Review of NMN and NR https://www.sciencedirect.com/science/article/pii/S1550413117306708 About NAD https://www.aboutnad.com/nad-precursors NR is orally bioavailable in humans and mice https://pubmed.ncbi.nlm.nih.gov/27721479/ NR increases lifespan in mice https://pubmed.ncbi.nlm.nih.gov/27127236/ NMN & NR research summary https://blog.insidetracker.com/nr-nmn-longevity-supplements-work-humans Similar studies with similar results have been seen with NMN. https://www.youtube-nocookie.com/embed/o6D8hXayG9M 257 2022-06-19T22:56:00.000Z 2026-10-23T00:51:10.536Z https://longevityharbor.com/de/watch/o6D8hXayG9M NMN Vs NR For Longevity | Comparing NAD Booster Supplements https://i.ytimg.com/vi/o6D8hXayG9M/hqdefault.jpg NMN and NR are both NAD boosters...so which is better? In this video I will discuss the difference between NAD, NMN and NR, explaining how they work to increase lifespan and improve your overall health. Free Gift: Guide for the 5 best supplements you can take: https://bit.ly/3CaLQCM NAD stands Nicotinamide Adenine Dinucleotide and its important in your mitochondria, helping you convert food into energy. NAD is also important for maintaining your DNA to protect you from ageing and disease. Unfortunately, your levels of NAD naturally decline as you get older Nicotinamide MonoNucleotide (NMN) is a precursor of NAD, & Nicotinamide Riboside (NR) is a precursor of NMN You can take both NMN and NR orally and they both move into your bloodstream and get taken up into all of your cells. NR is nice and small, so it gets taken up into your cells via a transporter, but NMN is medium sized and sometimes it can be taken up your cells...but sometimes it needs to be broken down into NR before it can move into your cells. ANYWAY, once it’s in the cell, NR turns into NMN, NMN turns into NAD, and NAD works to make more energy and it also activates sirtuins, which slow down the ageing process. Studies have shown that Yeast strains can live 30% longer when given NR, and mice have been shown to live 9% longer when given NR. Those mice also had more energy, less inflammation, and were generally healthier than the mice that didn’t receive NR NMN vs NR Website https://www.nmn.com/precursors/nmn-vs-nr Sirtuins and NAD boosters https://www.nature.com/articles/nrm.2016.93 2018 Review of NMN and NR https://www.sciencedirect.com/science/article/pii/S1550413117306708 About NAD https://www.aboutnad.com/nad-precursors NR is orally bioavailable in humans and mice https://pubmed.ncbi.nlm.nih.gov/27721479/ NR increases lifespan in mice https://pubmed.ncbi.nlm.nih.gov/27127236/ NMN & NR research summary https://blog.insidetracker.com/nr-nmn-longevity-supplements-work-humans Similar studies with similar results have been seen with NMN. https://www.youtube-nocookie.com/embed/o6D8hXayG9M 257 2022-06-19T22:56:00.000Z 2026-10-23T00:51:10.536Z https://longevityharbor.com/en/watch/o6Uc_11TZM0 Pros & cons of GLP-1 weight loss drugs | Dr. Ralph DeFronzo https://i.ytimg.com/vi/o6Uc_11TZM0/hqdefault.jpg This clip is from episode #337 – Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment with Ralph DeFronzo, M.D. In this clip, they discuss: - Are there any concerns with the current generation of GLP-1s other than the economic aspects that come with them? - The fascinating world of GLP-1 drugs and their profound impact on weight loss, muscle mass, and insulin sensitivity. - The potential risks and benefits, the science behind muscle preservation, and the exciting advancements in the pipeline. -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medica https://www.youtube-nocookie.com/embed/o6Uc_11TZM0 116 2025-03-01T17:00:57.000Z 2026-10-22T19:54:15.618Z https://longevityharbor.com/de/watch/o6Uc_11TZM0 Pros & cons of GLP-1 weight loss drugs | Dr. Ralph DeFronzo https://i.ytimg.com/vi/o6Uc_11TZM0/hqdefault.jpg This clip is from episode #337 – Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment with Ralph DeFronzo, M.D. In this clip, they discuss: - Are there any concerns with the current generation of GLP-1s other than the economic aspects that come with them? - The fascinating world of GLP-1 drugs and their profound impact on weight loss, muscle mass, and insulin sensitivity. - The potential risks and benefits, the science behind muscle preservation, and the exciting advancements in the pipeline. -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medica https://www.youtube-nocookie.com/embed/o6Uc_11TZM0 116 2025-03-01T17:00:57.000Z 2026-10-22T19:54:15.618Z https://longevityharbor.com/en/watch/o6hEHPjIHOI Reverse Aging: Dr David Sinclair on NMN & Anti Ageing supplements (including their side effects) https://i.ytimg.com/vi/o6hEHPjIHOI/hqdefault.jpg Looking for more data news? Follow us on Twitter https://twitter.com/worldofdaas 🌐 The trusted news feed on Data-as-a-Service (DaaS) companies and products 🌐 --------------------------------------------------------- David Sinclair is a professor of genetics at Harvard Medical School and the founder of the Sinclair Lab. He’s the author of the bestselling book Lifespan: Why We Age—and Why We Don’t Have To, as well as a founder of several biotech companies. #bestsellingbook #biotechnology #genetics Auren and David discuss the potential to expand the average human lifespan by decades. David challenges traditional notions of aging and emphasizes the need to embrace new technologies. They also discuss the benefits and drawbacks of standard anti-aging practices like interval training, fasting, and stress reduction. David shares his thoughts on what longevity medicines and supplements are most beneficial, and how to talk to your doctor about them. He breaks down which health metrics to monitor in treating and preventing aging. Overall, David offers an incredibly optimistic vision for what the future of aging could look like, and the science it will take to get there. Top podcast episodes: https://www.youtube.com/watch?v=UP3A6kz2fkw https://www.youtube.com/watch?v=QL6BgXUcb_0 https://www.youtube.com/watch?v=lKzwNXeBgjQ https://www.youtube.com/watch?v=7t_W2TcGUZk https://www.youtube.com/watch?v=Onkv42L2B8c https://www.youtube.com/watch?v=uy8LH2WK94M https://www.youtube.com/watch?v=zsMvGZmW9MI https://www.youtube.com/watch?v=-WkynIAKVAU Recent podcast episodes: https://www.youtube.com/watch?v=7mW8r0iwGzM https://www.youtube.com/watch?v=sOfWnBcBdPY https://www.youtube.com/watch?v=cj5Id2stc28 https://www.youtube.com/watch?v=pgVoZmmez1o https://www.youtube.com/watch?v=_qhaJO4EFEI https://www.youtube.com/watch?v=hOsJhLL50qY https://www.youtube.com/watch?v=jyo1rF4iEZ4 https://www.youtube.com/watch?v=p4XBbP1-MSA World of DaaS is brought to you by SafeGraph & Flex Capital. For more episodes, visit safegraph.com/podcas https://www.youtube-nocookie.com/embed/o6hEHPjIHOI 857 2023-08-12T13:00:42.000Z 2026-10-23T00:51:10.552Z https://longevityharbor.com/de/watch/o6hEHPjIHOI Reverse Aging: Dr David Sinclair on NMN & Anti Ageing supplements (including their side effects) https://i.ytimg.com/vi/o6hEHPjIHOI/hqdefault.jpg Looking for more data news? Follow us on Twitter https://twitter.com/worldofdaas 🌐 The trusted news feed on Data-as-a-Service (DaaS) companies and products 🌐 --------------------------------------------------------- David Sinclair is a professor of genetics at Harvard Medical School and the founder of the Sinclair Lab. He’s the author of the bestselling book Lifespan: Why We Age—and Why We Don’t Have To, as well as a founder of several biotech companies. #bestsellingbook #biotechnology #genetics Auren and David discuss the potential to expand the average human lifespan by decades. David challenges traditional notions of aging and emphasizes the need to embrace new technologies. They also discuss the benefits and drawbacks of standard anti-aging practices like interval training, fasting, and stress reduction. David shares his thoughts on what longevity medicines and supplements are most beneficial, and how to talk to your doctor about them. He breaks down which health metrics to monitor in treating and preventing aging. Overall, David offers an incredibly optimistic vision for what the future of aging could look like, and the science it will take to get there. Top podcast episodes: https://www.youtube.com/watch?v=UP3A6kz2fkw https://www.youtube.com/watch?v=QL6BgXUcb_0 https://www.youtube.com/watch?v=lKzwNXeBgjQ https://www.youtube.com/watch?v=7t_W2TcGUZk https://www.youtube.com/watch?v=Onkv42L2B8c https://www.youtube.com/watch?v=uy8LH2WK94M https://www.youtube.com/watch?v=zsMvGZmW9MI https://www.youtube.com/watch?v=-WkynIAKVAU Recent podcast episodes: https://www.youtube.com/watch?v=7mW8r0iwGzM https://www.youtube.com/watch?v=sOfWnBcBdPY https://www.youtube.com/watch?v=cj5Id2stc28 https://www.youtube.com/watch?v=pgVoZmmez1o https://www.youtube.com/watch?v=_qhaJO4EFEI https://www.youtube.com/watch?v=hOsJhLL50qY https://www.youtube.com/watch?v=jyo1rF4iEZ4 https://www.youtube.com/watch?v=p4XBbP1-MSA World of DaaS is brought to you by SafeGraph & Flex Capital. For more episodes, visit safegraph.com/podcas https://www.youtube-nocookie.com/embed/o6hEHPjIHOI 857 2023-08-12T13:00:42.000Z 2026-10-23T00:51:10.552Z https://longevityharbor.com/en/watch/o76OCyOEmVA Video description links poor sleep to faster biological aging https://i.ytimg.com/vi/o76OCyOEmVA/hqdefault.jpg The description says the video explains how sleep quality may affect biological age, cells, skin and brain, and covers circadian rhythm and telomere shortening. The video itself was not reviewed. https://www.youtube-nocookie.com/embed/o76OCyOEmVA 351 2026-10-05T12:46:55.000Z 2026-10-22T21:21:01.970Z https://longevityharbor.com/de/watch/o76OCyOEmVA Videobeschreibung verknüpft schlechten Schlaf mit schnellerem biologischen Altern https://i.ytimg.com/vi/o76OCyOEmVA/hqdefault.jpg Laut Beschreibung erklärt das Video, wie Schlafqualität das biologische Alter, Zellen, Haut und Gehirn beeinflussen kann, und behandelt circadianen Rhythmus sowie Telomerverkürzung. Das Video selbst wurde nicht geprüft. https://www.youtube-nocookie.com/embed/o76OCyOEmVA 351 2026-10-05T12:46:55.000Z 2026-10-22T21:21:01.970Z https://longevityharbor.com/en/watch/oBTS3Cabo54 NMN and NR supplements: what the video says human evidence shows https://i.ytimg.com/vi/oBTS3Cabo54/hqdefault.jpg The description says NMN and NR raise NAD⁺ levels, but whether that improves health, function or aging in humans remains the harder question it addresses. https://www.youtube-nocookie.com/embed/oBTS3Cabo54 97 2026-06-12T13:30:24.000Z 2026-10-23T00:00:04.661Z https://longevityharbor.com/de/watch/oBTS3Cabo54 NMN- und NR-Präparate: Was das Video zur Humanevidenz sagt https://i.ytimg.com/vi/oBTS3Cabo54/hqdefault.jpg Laut Beschreibung erhöhen NMN und NR den NAD⁺-Spiegel; ob das Gesundheit, Funktion oder Altern beim Menschen verbessert, bleibt die schwierigere Frage, die das Video behandelt. https://www.youtube-nocookie.com/embed/oBTS3Cabo54 97 2026-06-12T13:30:24.000Z 2026-10-23T00:00:04.661Z https://longevityharbor.com/en/watch/oC-nXkgz0P4 Rapamycin and lean mass: description claims new data, not proof https://i.ytimg.com/vi/oC-nXkgz0P4/hqdefault.jpg The video description says the idea that mTOR helps muscle but harms aging is too simple, and that new data suggest off-label rapamycin may preserve lean mass; more research is needed. https://www.youtube-nocookie.com/embed/oC-nXkgz0P4 106 2026-06-06T16:17:19.000Z 2026-10-23T00:06:59.668Z https://longevityharbor.com/de/watch/oC-nXkgz0P4 Rapamycin und fettfreie Masse: Beschreibung nennt neue Daten, keinen Beweis https://i.ytimg.com/vi/oC-nXkgz0P4/hqdefault.jpg Die Videobeschreibung sagt, das Bild von mTOR als muskelgünstig, aber alterungsschädlich sei zu einfach, und neue Daten deuteten darauf hin, dass Off-Label-Rapamycin fettfreie Masse erhalten könnte; mehr Forschung sei nötig. https://www.youtube-nocookie.com/embed/oC-nXkgz0P4 106 2026-06-06T16:17:19.000Z 2026-10-23T00:06:59.668Z https://longevityharbor.com/en/watch/oDHa-YyeVCI Video description: 2026 NMN vs NR trials, dosing, safety and supplement quality https://i.ytimg.com/vi/oDHa-YyeVCI/hqdefault.jpg The description says two 2026 human trials compared NMN and NR: in one, the NMN arm was stopped early because NR raised blood NAD+ 2.3 times more effectively, while a second trial found them essentially tied. It also promises coverage of doses, safety, a cancer warning, label-testing failures and whether raising NAD+ extends lifespan. https://www.youtube-nocookie.com/embed/oDHa-YyeVCI 455 2026-05-02T14:30:00.000Z 2026-10-23T01:19:25.747Z https://longevityharbor.com/de/watch/oDHa-YyeVCI Videobeschreibung: NMN-gegen-NR-Studien 2026, Dosierung, Sicherheit und Produktqualität https://i.ytimg.com/vi/oDHa-YyeVCI/hqdefault.jpg Laut Beschreibung verglichen zwei Humanstudien aus 2026 NMN und NR: In einer wurde der NMN-Arm früh beendet, weil NR den NAD+-Blutspiegel 2,3-mal wirksamer erhöhte; eine zweite Studie fand beide im Wesentlichen gleichauf. Zudem werden Dosierungen, Sicherheit, eine Krebswarnung, fehlgeschlagene Etikettentests und die Frage behandelt, ob ein höherer NAD+-Spiegel die Lebensspanne verlängert. https://www.youtube-nocookie.com/embed/oDHa-YyeVCI 455 2026-05-02T14:30:00.000Z 2026-10-23T01:19:25.747Z https://longevityharbor.com/en/watch/oDXYZyXo7-Q UC Berkeley Aging & Longevity Conference Day 2 - Dr Karl R Pfleger (VC & Angel Investor) 3-May-'26 https://i.ytimg.com/vi/oDXYZyXo7-Q/hqdefault.jpg Motivation for, Status of, & Path to Eliminating Aging https://www.youtube-nocookie.com/embed/oDXYZyXo7-Q 1983 2026-05-13T04:31:06.000Z 2026-10-22T19:54:20.200Z https://longevityharbor.com/de/watch/oDXYZyXo7-Q UC Berkeley Aging & Longevity Conference Day 2 - Dr Karl R Pfleger (VC & Angel Investor) 3-May-'26 https://i.ytimg.com/vi/oDXYZyXo7-Q/hqdefault.jpg Motivation for, Status of, & Path to Eliminating Aging https://www.youtube-nocookie.com/embed/oDXYZyXo7-Q 1983 2026-05-13T04:31:06.000Z 2026-10-22T19:54:20.200Z https://longevityharbor.com/en/watch/oFcndSj1dII How to Activate AMPK and Suppress mTOR for Longevity | GlobalRPh https://i.ytimg.com/vi/oFcndSj1dII/hqdefault.jpg How to Activate AMPK and Suppress mTOR for Longevity | GlobalRPh https://globalrph.com/globalrph-video-section/ In this in-depth clinical lecture, we examine two central nutrient-sensing pathways that shape human aging and metabolic resilience: AMPK activation and mTOR suppression. These molecular regulators influence autophagy, mitochondrial efficiency, insulin sensitivity, cellular repair, and long-term cardiometabolic risk. Using current clinical data and mechanistic insights, this session explains how dietary structure directly modulates these longevity pathways. Rather than focusing on trends, we break down the physiology behind meal timing, macronutrient balance, and nutrient signaling so clinicians can translate science into practice. What this lecture covers: • The metabolic rationale behind delayed breakfast and earlier evening meals • How protein quantity and timing influence mTOR activity • The role of time-restricted eating in enhancing autophagy and metabolic flexibility • AMPK as a master regulator of energy balance and mitochondrial function • How polyphenols and plant-forward dietary patterns support cellular stress resistance • Practical counseling strategies for implementing longevity-focused nutrition plans Designed for physicians, nurse practitioners, pharmacists, dietitians, endocrinologists, geriatric specialists, and researchers, this lecture bridges molecular biology and clinical application. If you are working in preventive medicine, metabolic care, aging science, or functional nutrition, this session provides a clear, evidence-based framework for using dietary interventions to influence biological aging pathways. Subscribe to GlobalRPh for clinically rigorous education on pharmacology, metabolic regulation, and translational longevity science. #LongevityMedicine #AMPK #mTOR #Autophagy #TimeRestrictedEating #IntermittentFasting #HealthyAging #ClinicalNutrition #MetabolicHealth #PreventiveMedicine #NutritionScience #FunctionalMedicine #GlobalRPh https://www.youtube-nocookie.com/embed/oFcndSj1dII 362 2025-07-11T16:03:15.000Z 2026-10-22T19:32:35.452Z https://longevityharbor.com/de/watch/oFcndSj1dII How to Activate AMPK and Suppress mTOR for Longevity | GlobalRPh https://i.ytimg.com/vi/oFcndSj1dII/hqdefault.jpg How to Activate AMPK and Suppress mTOR for Longevity | GlobalRPh https://globalrph.com/globalrph-video-section/ In this in-depth clinical lecture, we examine two central nutrient-sensing pathways that shape human aging and metabolic resilience: AMPK activation and mTOR suppression. These molecular regulators influence autophagy, mitochondrial efficiency, insulin sensitivity, cellular repair, and long-term cardiometabolic risk. Using current clinical data and mechanistic insights, this session explains how dietary structure directly modulates these longevity pathways. Rather than focusing on trends, we break down the physiology behind meal timing, macronutrient balance, and nutrient signaling so clinicians can translate science into practice. What this lecture covers: • The metabolic rationale behind delayed breakfast and earlier evening meals • How protein quantity and timing influence mTOR activity • The role of time-restricted eating in enhancing autophagy and metabolic flexibility • AMPK as a master regulator of energy balance and mitochondrial function • How polyphenols and plant-forward dietary patterns support cellular stress resistance • Practical counseling strategies for implementing longevity-focused nutrition plans Designed for physicians, nurse practitioners, pharmacists, dietitians, endocrinologists, geriatric specialists, and researchers, this lecture bridges molecular biology and clinical application. If you are working in preventive medicine, metabolic care, aging science, or functional nutrition, this session provides a clear, evidence-based framework for using dietary interventions to influence biological aging pathways. Subscribe to GlobalRPh for clinically rigorous education on pharmacology, metabolic regulation, and translational longevity science. #LongevityMedicine #AMPK #mTOR #Autophagy #TimeRestrictedEating #IntermittentFasting #HealthyAging #ClinicalNutrition #MetabolicHealth #PreventiveMedicine #NutritionScience #FunctionalMedicine #GlobalRPh https://www.youtube-nocookie.com/embed/oFcndSj1dII 362 2025-07-11T16:03:15.000Z 2026-10-22T19:32:35.452Z https://longevityharbor.com/en/watch/oIr-ofm8cc8 4 4 Epigenetic modifications https://i.ytimg.com/vi/oIr-ofm8cc8/hqdefault.jpg Gene expression is heavily governed by epigenetic modifications that alter chromatin architecture without changing the underlying DNA sequence. Key words: Robbins basic pathology, pathology audiobook, Epigenetic modifications, DNA Methylation, Histone Modifications, Genomic Imprinting https://www.youtube-nocookie.com/embed/oIr-ofm8cc8 94 2026-10-10T10:57:15.000Z 2026-10-22T19:43:50.990Z https://longevityharbor.com/de/watch/oIr-ofm8cc8 4 4 Epigenetic modifications https://i.ytimg.com/vi/oIr-ofm8cc8/hqdefault.jpg Gene expression is heavily governed by epigenetic modifications that alter chromatin architecture without changing the underlying DNA sequence. Key words: Robbins basic pathology, pathology audiobook, Epigenetic modifications, DNA Methylation, Histone Modifications, Genomic Imprinting https://www.youtube-nocookie.com/embed/oIr-ofm8cc8 94 2026-10-10T10:57:15.000Z 2026-10-22T19:43:50.990Z https://longevityharbor.com/en/watch/oMgaqRPEGd8 Video description: intermittent fasting, a claimed 91% heart-death risk and controlled trials https://i.ytimg.com/vi/oMgaqRPEGd8/hqdefault.jpg The description says the video examines a 2025 study claim that intermittent fasting raises cardiovascular death risk by 91 percent, what that research actually showed, and what controlled trials say. https://www.youtube-nocookie.com/embed/oMgaqRPEGd8 582 2026-08-29T09:31:49.000Z 2026-10-22T22:39:41.293Z https://longevityharbor.com/de/watch/oMgaqRPEGd8 Videobeschreibung: Intervallfasten, behauptetes 91-Prozent-Herzrisiko und kontrollierte Studien https://i.ytimg.com/vi/oMgaqRPEGd8/hqdefault.jpg Laut Beschreibung prüft das Video die Aussage einer Studie von 2025, Intervallfasten erhöhe das kardiovaskuläre Sterberisiko um 91 Prozent, was diese Forschung tatsächlich zeigte und was kontrollierte Studien sagen. https://www.youtube-nocookie.com/embed/oMgaqRPEGd8 582 2026-08-29T09:31:49.000Z 2026-10-22T22:39:41.293Z https://longevityharbor.com/en/watch/oXZuYnMmlAE Can Fasting Really Make You Live Longer? #shorts #longevity #livelonger #intermittentfasting https://i.ytimg.com/vi/oXZuYnMmlAE/hqdefault.jpg Can fasting really help you live longer? ⏳ In this short, we break down the science behind fasting and its potential to boost longevity. What do you think? Drop a comment below! 👇 https://www.youtube-nocookie.com/embed/oXZuYnMmlAE 142 2024-11-18T21:00:37.000Z 2026-10-22T19:32:30.934Z https://longevityharbor.com/de/watch/oXZuYnMmlAE Can Fasting Really Make You Live Longer? #shorts #longevity #livelonger #intermittentfasting https://i.ytimg.com/vi/oXZuYnMmlAE/hqdefault.jpg Can fasting really help you live longer? ⏳ In this short, we break down the science behind fasting and its potential to boost longevity. What do you think? Drop a comment below! 👇 https://www.youtube-nocookie.com/embed/oXZuYnMmlAE 142 2024-11-18T21:00:37.000Z 2026-10-22T19:32:30.934Z https://longevityharbor.com/en/watch/oeVfCqlHn_I Tools to Set Your Cortisol Rhythm https://i.ytimg.com/vi/oeVfCqlHn_I/hqdefault.jpg Getting your cortisol rhythm correct is essential to energy and sleep and much more. The new Huberman Lab episode covers everything you need to know about how to get your cortisol rhythm correct. You want high levels of cortisol in the morning and late morning and low levels at night. I teach you how to do that and the biology underlying the protocols. Caffeine surprisingly does not increase cortisol very much if you drink it regularly. If you don’t drink it regularly it will increase cortisol. Deliberate cold exposure does not increase cortisol very much; in fact, it can decrease your cortisol levels if you do it regularly. Yep, you read right. Two times per week or more is regularly. Exercise is best done in the early part of the day to match your circadian cortisol rhythm, but if you can’t do it early in the day (and many of us can’t) exercise in the afternoon or evening should be followed by a few simple things to lower your cortisol. I discussed those in the episode. Otherwise, your next-morning cortisol is reduced and, over time, this can lead to type 2 burnout (explained on the episode and how to overcome it). Licorice root is a potent elevator of cortisol. This can be used early in the day but approach with caution. It can interact with medications. I’ve been using it in the morning and it’s great. Same goes for grapefruit, although grapefruit works through a different mechanism. It increases the duration over which cortisol is active and is less potent than licorice for cortisol. The episode also explains how nutrition impacts cortisol, low-carb diets, and more. Lots in there and it’s all time-stamped so you can navigate quickly to the topic most of interest to you. https://www.youtube-nocookie.com/embed/oeVfCqlHn_I 175 2025-08-06T18:38:06.000Z 2026-10-22T19:21:25.323Z https://longevityharbor.com/de/watch/oeVfCqlHn_I Tools to Set Your Cortisol Rhythm https://i.ytimg.com/vi/oeVfCqlHn_I/hqdefault.jpg Getting your cortisol rhythm correct is essential to energy and sleep and much more. The new Huberman Lab episode covers everything you need to know about how to get your cortisol rhythm correct. You want high levels of cortisol in the morning and late morning and low levels at night. I teach you how to do that and the biology underlying the protocols. Caffeine surprisingly does not increase cortisol very much if you drink it regularly. If you don’t drink it regularly it will increase cortisol. Deliberate cold exposure does not increase cortisol very much; in fact, it can decrease your cortisol levels if you do it regularly. Yep, you read right. Two times per week or more is regularly. Exercise is best done in the early part of the day to match your circadian cortisol rhythm, but if you can’t do it early in the day (and many of us can’t) exercise in the afternoon or evening should be followed by a few simple things to lower your cortisol. I discussed those in the episode. Otherwise, your next-morning cortisol is reduced and, over time, this can lead to type 2 burnout (explained on the episode and how to overcome it). Licorice root is a potent elevator of cortisol. This can be used early in the day but approach with caution. It can interact with medications. I’ve been using it in the morning and it’s great. Same goes for grapefruit, although grapefruit works through a different mechanism. It increases the duration over which cortisol is active and is less potent than licorice for cortisol. The episode also explains how nutrition impacts cortisol, low-carb diets, and more. Lots in there and it’s all time-stamped so you can navigate quickly to the topic most of interest to you. https://www.youtube-nocookie.com/embed/oeVfCqlHn_I 175 2025-08-06T18:38:06.000Z 2026-10-22T19:21:25.323Z https://longevityharbor.com/en/watch/olB7rIpQ0CA Podcast: Brian Kennedy on aging clocks, biomarkers and Singapore's 'blue zone' https://i.ytimg.com/vi/olB7rIpQ0CA/hqdefault.jpg In this podcast description, Brian Kennedy discusses aging clocks, biomarkers, supplements and Singapore's 'blue zone'-like healthy living, plus biobank plans in Singapore and India. The description does not report results. https://www.youtube-nocookie.com/embed/olB7rIpQ0CA 2532 2026-02-02T10:55:17.000Z 2026-10-23T02:41:27.622Z https://longevityharbor.com/de/watch/olB7rIpQ0CA Podcast: Brian Kennedy über Altersuhren, Biomarker und Singapurs „Blue Zone“ https://i.ytimg.com/vi/olB7rIpQ0CA/hqdefault.jpg In dieser Podcast-Beschreibung spricht Brian Kennedy über Altersuhren, Biomarker, Nahrungsergänzungsmittel und Singapurs „Blue-Zone“-ähnliches gesundes Leben sowie Biobank-Pläne in Singapur und Indien. Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/olB7rIpQ0CA 2532 2026-02-02T10:55:17.000Z 2026-10-23T02:41:27.622Z https://longevityharbor.com/en/watch/olaKqwZm5G8 SABCS 2023: Implications of Senescence for Breast Cancer Biology and Treatment https://i.ytimg.com/vi/olaKqwZm5G8/hqdefault.jpg Justin Balko, PharmD, PhD moderates a session focused on the implications of breast cancer cellular senescence on treatment: 1. Cellular senescence: The senescence-associated secretory phenotype (SASP) and immunity: Marcus Ruscetti, PhD 2. Implications of therapy induced senescence in breast cancer: James G. Jackson, PhD 3. Influence clinical trial and new therapeutics: Shom Goel, B Med Sci (Hons), MBBS (Hons), FRACP, PhD https://www.youtube-nocookie.com/embed/olaKqwZm5G8 3984 2024-04-01T15:46:14.000Z 2026-10-22T19:21:22.957Z https://longevityharbor.com/de/watch/olaKqwZm5G8 SABCS 2023: Implications of Senescence for Breast Cancer Biology and Treatment https://i.ytimg.com/vi/olaKqwZm5G8/hqdefault.jpg Justin Balko, PharmD, PhD moderates a session focused on the implications of breast cancer cellular senescence on treatment: 1. Cellular senescence: The senescence-associated secretory phenotype (SASP) and immunity: Marcus Ruscetti, PhD 2. Implications of therapy induced senescence in breast cancer: James G. Jackson, PhD 3. Influence clinical trial and new therapeutics: Shom Goel, B Med Sci (Hons), MBBS (Hons), FRACP, PhD https://www.youtube-nocookie.com/embed/olaKqwZm5G8 3984 2024-04-01T15:46:14.000Z 2026-10-22T19:21:22.957Z https://longevityharbor.com/en/watch/oxFnSykrV5w 2023 Biomarkers of Aging Symposium - Recording 2 of 2 https://i.ytimg.com/vi/oxFnSykrV5w/hqdefault.jpg The full recordings of our 2023 Biomarkers of Aging Symposium are made available to our newsletter audience. Please note that this is recording 2 of 2. Recording 1 of 2 can can be found here: https://youtu.be/bpDI7QpTe2g. Enjoy! ⏰ TIMESTAMPS [00:00] Biomarker Validation Panel [42:30] Short Talk: "Pace of Aging Biomarkers for Geroscience" by Daniel Belsky [1:00:32] Short Talk: "Conceptual Challenges in the Definition and Measurement of Aging via Biomarkers" by Alan Cohen [1:15:10] Short Talk: "Aging & Mental Health: Effects of Stress and Medications" by Albert Higgins-Chen [2:05:05] Industry Panel [2:53:45: Short Talk: "Biomarkers for Human Longevity" by Nir Barzilai [3:13:21] Short Talk: "XPRIZE Healthspan" by Jamie Justice [3:33:35] 2024 Look Ahead: Biomarkers of Aging Challenge and Beyond with Jesse Poganik [3:38:38] Biomarkers of Aging 2024 Challenge Series Announcement with Dane Gobel [3:48:00] Poster Awards [3:50:55] Thank Yous & Wrap Up with Vadim Gladyshev, Jesse Poganik, Dane Gobel, and Mahdi Moqri https://www.youtube-nocookie.com/embed/oxFnSykrV5w 14276 2024-12-11T11:32:53.000Z 2026-10-22T18:32:11.666Z https://longevityharbor.com/de/watch/oxFnSykrV5w 2023 Biomarkers of Aging Symposium - Recording 2 of 2 https://i.ytimg.com/vi/oxFnSykrV5w/hqdefault.jpg The full recordings of our 2023 Biomarkers of Aging Symposium are made available to our newsletter audience. Please note that this is recording 2 of 2. Recording 1 of 2 can can be found here: https://youtu.be/bpDI7QpTe2g. Enjoy! ⏰ TIMESTAMPS [00:00] Biomarker Validation Panel [42:30] Short Talk: "Pace of Aging Biomarkers for Geroscience" by Daniel Belsky [1:00:32] Short Talk: "Conceptual Challenges in the Definition and Measurement of Aging via Biomarkers" by Alan Cohen [1:15:10] Short Talk: "Aging & Mental Health: Effects of Stress and Medications" by Albert Higgins-Chen [2:05:05] Industry Panel [2:53:45: Short Talk: "Biomarkers for Human Longevity" by Nir Barzilai [3:13:21] Short Talk: "XPRIZE Healthspan" by Jamie Justice [3:33:35] 2024 Look Ahead: Biomarkers of Aging Challenge and Beyond with Jesse Poganik [3:38:38] Biomarkers of Aging 2024 Challenge Series Announcement with Dane Gobel [3:48:00] Poster Awards [3:50:55] Thank Yous & Wrap Up with Vadim Gladyshev, Jesse Poganik, Dane Gobel, and Mahdi Moqri https://www.youtube-nocookie.com/embed/oxFnSykrV5w 14276 2024-12-11T11:32:53.000Z 2026-10-22T18:32:11.666Z https://longevityharbor.com/en/watch/oyE_GIppql8 Podcast talk: Michalsen on calorie restriction, food matrix and fructose https://i.ytimg.com/vi/oyE_GIppql8/hqdefault.jpg In this podcast description, Prof. Andreas Michalsen calls calorie restriction the best-supported method for extending life and recommends leaving the table slightly hungry; the conversation also covers fructose, food matrix, fibre, CGM and methionine. https://www.youtube-nocookie.com/embed/oyE_GIppql8 3559 2026-03-01T05:00:06.000Z 2026-10-23T02:19:15.814Z https://longevityharbor.com/de/watch/oyE_GIppql8 Podcast-Gespräch: Michalsen über Kalorienrestriktion, Lebensmittelmatrix und Fruktose https://i.ytimg.com/vi/oyE_GIppql8/hqdefault.jpg In dieser Podcast-Beschreibung nennt Prof. Andreas Michalsen Kalorienrestriktion die am besten gesicherte Methode zur Lebensverlängerung und empfiehlt, den Tisch mit leichtem Hunger zu verlassen; zudem geht es um Fruktose, Lebensmittelmatrix, Ballaststoffe, CGM und Methionin. https://www.youtube-nocookie.com/embed/oyE_GIppql8 3559 2026-03-01T05:00:06.000Z 2026-10-23T02:19:15.814Z https://longevityharbor.com/en/watch/pH7Hkl-NFM0 Title: Rapamycin for Longevity – Latest Science & Practical Insights https://i.ytimg.com/vi/pH7Hkl-NFM0/hqdefault.jpg In this video, I dive into the latest research on rapamycin for longevity, breaking down key findings from a 2024 Lancet Healthy Longevity article on its potential as an anti-aging therapy ( https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(23)00258-1/fulltext ). We’ll discuss how rapamycin works, its effects on mTOR inhibition, and the most common dosing strategies used in longevity protocols. Additionally, I highlight key insights from Peter Attia’s podcast with leading experts David Sabatini & Matt Kaeberlein, where they explore rapamycin’s potential to extend lifespan, its risks, and what human trials are telling us so far ( https://peterattiamd.com/davidsabatini-mattkaeberlein/ ). Topics Covered: ✅ How Rapamycin Works for Longevity & Aging ✅ Latest Clinical Findings & Animal Study Insights ✅ Common Dosing Protocols for Longevity (6-10mg Weekly?) ✅ Risks, Side Effects & Who Should Consider It ✅ What Experts Like Peter Attia, David Sabatini, & Matt Kaeberlein Say ✅ Natural mTOR Inhibitors That Support Longevity Natural Substances That Inhibit mTOR: Several natural compounds have been shown to modulate or inhibit mTOR, potentially mimicking some of rapamycin's longevity effects: 🌱 Resveratrol – Found in grapes and red wine, known for its anti-inflammatory and longevity-promoting effects. 🥦 Sulforaphane – A potent compound in cruciferous vegetables like broccoli, linked to cellular protection and mTOR inhibition. 🫚 Curcumin – The active compound in turmeric, shown to modulate mTOR pathways and reduce inflammation. 🍵 EGCG (Epigallocatechin Gallate) – Found in green tea, supports autophagy and inhibits mTOR. 🌰 Quercetin – A flavonoid in onions and apples that helps reduce inflammation and modulate aging pathways. 🥑 Berberine – A plant alkaloid that mimics some effects of metformin and may influence mTOR signaling. 🍽 Fasting & Caloric Restriction – Naturally inhibits mTOR and promotes autophagy, enhancing cellular repair and longevity. 🔥 Ketogenic Diet & Low Protein Intake – Lowering diet https://www.youtube-nocookie.com/embed/pH7Hkl-NFM0 916 2025-02-11T14:43:45.000Z 2026-10-22T17:43:41.804Z https://longevityharbor.com/de/watch/pH7Hkl-NFM0 Title: Rapamycin for Longevity – Latest Science & Practical Insights https://i.ytimg.com/vi/pH7Hkl-NFM0/hqdefault.jpg In this video, I dive into the latest research on rapamycin for longevity, breaking down key findings from a 2024 Lancet Healthy Longevity article on its potential as an anti-aging therapy ( https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(23)00258-1/fulltext ). We’ll discuss how rapamycin works, its effects on mTOR inhibition, and the most common dosing strategies used in longevity protocols. Additionally, I highlight key insights from Peter Attia’s podcast with leading experts David Sabatini & Matt Kaeberlein, where they explore rapamycin’s potential to extend lifespan, its risks, and what human trials are telling us so far ( https://peterattiamd.com/davidsabatini-mattkaeberlein/ ). Topics Covered: ✅ How Rapamycin Works for Longevity & Aging ✅ Latest Clinical Findings & Animal Study Insights ✅ Common Dosing Protocols for Longevity (6-10mg Weekly?) ✅ Risks, Side Effects & Who Should Consider It ✅ What Experts Like Peter Attia, David Sabatini, & Matt Kaeberlein Say ✅ Natural mTOR Inhibitors That Support Longevity Natural Substances That Inhibit mTOR: Several natural compounds have been shown to modulate or inhibit mTOR, potentially mimicking some of rapamycin's longevity effects: 🌱 Resveratrol – Found in grapes and red wine, known for its anti-inflammatory and longevity-promoting effects. 🥦 Sulforaphane – A potent compound in cruciferous vegetables like broccoli, linked to cellular protection and mTOR inhibition. 🫚 Curcumin – The active compound in turmeric, shown to modulate mTOR pathways and reduce inflammation. 🍵 EGCG (Epigallocatechin Gallate) – Found in green tea, supports autophagy and inhibits mTOR. 🌰 Quercetin – A flavonoid in onions and apples that helps reduce inflammation and modulate aging pathways. 🥑 Berberine – A plant alkaloid that mimics some effects of metformin and may influence mTOR signaling. 🍽 Fasting & Caloric Restriction – Naturally inhibits mTOR and promotes autophagy, enhancing cellular repair and longevity. 🔥 Ketogenic Diet & Low Protein Intake – Lowering diet https://www.youtube-nocookie.com/embed/pH7Hkl-NFM0 916 2025-02-11T14:43:45.000Z 2026-10-22T17:43:41.804Z https://longevityharbor.com/en/watch/pHhloo634s4 The Enzyme mTOR as an Engine of Aging https://i.ytimg.com/vi/pHhloo634s4/hqdefault.jpg Inhibiting mTOR, the “master determinant of lifespan,” is considered the best validated aging regulator. So, how do you slow it down? This is the first video in a three-part series, so stay tuned for Inhibiting mTOR with Rapamycin for Extending Lifespan and Healthspan (https://nutritionfacts.org/video/inhibiting-mtor-with-rapamycin-for-extending-lifespan-and-healthspan) and Is Rapamycin a Universal Anti-Aging Drug? (https://nutritionfacts.org/video/is-rapamycin-a-universal-anti-aging-drug). For more on anti-aging, see: • Dietary Sources of the “Longevity Vitamin” Ergothioneine (https://nutritionfacts.org/video/dietary-sources-of-the-longevity-vitamin-ergothioneine) • Greens, Green Tea, and Nuts Put to the Test for Telomeres (https://nutritionfacts.org/video/greens-green-tea-and-nuts-put-to-the-test-for-telomeres/) • What to Eat to Prevent Telomere Shortening (https://nutritionfacts.org/video/what-to-eat-to-prevent-telomere-shortening/) • The Best Diet for Healthy Aging (https://nutritionfacts.org/video/the-best-diet-for-healthy-aging/) And, for more on aging, check out my longevity book, How Not to Age (https://nutritionfacts.org/book/how-not-to-age/), available in print, e-book, and audio. (All proceeds I receive from the book are donated directly to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/the-enzyme-mtor-as-an-engine-of-aging and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/the-enzyme-mtor-as-an-engine-of-aging. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. Thanks for watching. I hope you’ll join i https://www.youtube-nocookie.com/embed/pHhloo634s4 270 2024-11-18T12:59:51.000Z 2026-10-22T17:43:41.105Z https://longevityharbor.com/de/watch/pHhloo634s4 The Enzyme mTOR as an Engine of Aging https://i.ytimg.com/vi/pHhloo634s4/hqdefault.jpg Inhibiting mTOR, the “master determinant of lifespan,” is considered the best validated aging regulator. So, how do you slow it down? This is the first video in a three-part series, so stay tuned for Inhibiting mTOR with Rapamycin for Extending Lifespan and Healthspan (https://nutritionfacts.org/video/inhibiting-mtor-with-rapamycin-for-extending-lifespan-and-healthspan) and Is Rapamycin a Universal Anti-Aging Drug? (https://nutritionfacts.org/video/is-rapamycin-a-universal-anti-aging-drug). For more on anti-aging, see: • Dietary Sources of the “Longevity Vitamin” Ergothioneine (https://nutritionfacts.org/video/dietary-sources-of-the-longevity-vitamin-ergothioneine) • Greens, Green Tea, and Nuts Put to the Test for Telomeres (https://nutritionfacts.org/video/greens-green-tea-and-nuts-put-to-the-test-for-telomeres/) • What to Eat to Prevent Telomere Shortening (https://nutritionfacts.org/video/what-to-eat-to-prevent-telomere-shortening/) • The Best Diet for Healthy Aging (https://nutritionfacts.org/video/the-best-diet-for-healthy-aging/) And, for more on aging, check out my longevity book, How Not to Age (https://nutritionfacts.org/book/how-not-to-age/), available in print, e-book, and audio. (All proceeds I receive from the book are donated directly to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/the-enzyme-mtor-as-an-engine-of-aging and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/the-enzyme-mtor-as-an-engine-of-aging. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. Thanks for watching. I hope you’ll join i https://www.youtube-nocookie.com/embed/pHhloo634s4 270 2024-11-18T12:59:51.000Z 2026-10-22T17:43:41.105Z https://longevityharbor.com/en/watch/pIS-rfoBO3w Gesunde Ernährung im Alter - eine ganzheitliche Betrachtung mit Verena Mundorf (Teil 1) https://i.ytimg.com/vi/pIS-rfoBO3w/hqdefault.jpg Lässt sich Lebensqualität im Alter durch Ernährung steigern? Welche Komponenten sich günstig auf die Ernährung im Alter auswirken und was genau Ernährungsdichte ist, erklärt die Ernährungsberaterin Verena Mundorf. Im ersten Teil gibt sie ganz konkrete Beispiele für gesunde Komponenten der Ernährung Ihr Regionalbüro Alter, Pflege und Demenz Bergisches Land https://www.youtube-nocookie.com/embed/pIS-rfoBO3w 966 2022-12-14T10:30:58.000Z 2026-10-23T01:21:29.701Z https://longevityharbor.com/de/watch/pIS-rfoBO3w Gesunde Ernährung im Alter - eine ganzheitliche Betrachtung mit Verena Mundorf (Teil 1) https://i.ytimg.com/vi/pIS-rfoBO3w/hqdefault.jpg Lässt sich Lebensqualität im Alter durch Ernährung steigern? Welche Komponenten sich günstig auf die Ernährung im Alter auswirken und was genau Ernährungsdichte ist, erklärt die Ernährungsberaterin Verena Mundorf. Im ersten Teil gibt sie ganz konkrete Beispiele für gesunde Komponenten der Ernährung Ihr Regionalbüro Alter, Pflege und Demenz Bergisches Land https://www.youtube-nocookie.com/embed/pIS-rfoBO3w 966 2022-12-14T10:30:58.000Z 2026-10-23T01:21:29.701Z https://longevityharbor.com/en/watch/pImU6VSR55Q Video description: fasting and longevity research claims https://i.ytimg.com/vi/pImU6VSR55Q/hqdefault.jpg The description says Dr. Max MacCloud examines whether periodic fasting can truly increase longevity and presents research on fasting, time-restricted eating and aging. It states no results, numbers or study details. https://www.youtube-nocookie.com/embed/pImU6VSR55Q 453 2026-04-04T14:45:05.000Z 2026-10-23T01:45:14.561Z https://longevityharbor.com/de/watch/pImU6VSR55Q Videobeschreibung: Fasten und Langlebigkeitsforschung https://i.ytimg.com/vi/pImU6VSR55Q/hqdefault.jpg Laut Beschreibung prüft Dr. Max MacCloud, ob periodisches Fasten die Langlebigkeit wirklich erhöhen kann, und stellt Forschung zu Fasten, zeitlich begrenztem Essen und Altern vor. Ergebnisse, Zahlen oder Studiendetails nennt sie nicht. https://www.youtube-nocookie.com/embed/pImU6VSR55Q 453 2026-04-04T14:45:05.000Z 2026-10-23T01:45:14.561Z https://longevityharbor.com/en/watch/pKupQOqYDww Nr. 1 Muskel-Experte: Das Geheimnis für starke Muskeln in jedem Alter | Prof. Ingo Froböse https://i.ytimg.com/vi/pKupQOqYDww/hqdefault.jpg Die Muskulatur ist unser größtes Stoffwechselorgan – entscheidend für Gesundheit, Leistungsfähigkeit und ein langes Leben. Und doch wird ihre Bedeutung noch immer unterschätzt. Darüber sprechen wir mit Prof. Dr. Ingo Froböse (@formelfroboese), einem der bekanntesten Sportwissenschaftler Deutschlands, Universitätsprofessor an der Deutschen Sporthochschule Köln und Autor von über 40 Büchern. Seit Jahrzehnten erforscht er, wie Bewegung, Prävention und Gesundheit zusammenwirken. Im ERCM Medizin Podcast erklärt er, warum Muskulatur heute als endokrines Organ gilt, welche Botenstoffe aktive Muskeln ausschütten (Myokine) – und wie diese unser Immun-, Hormon- und Herz-Kreislauf-System beeinflussen. Ingo Froböse zeigt auch, weshalb Muskelabbau (Sarkopenie) kein unausweichliches Schicksal ist – und wie Muskeln in jedem Alter gezielt aufgebaut und erhalten werden können, um Vitalität und Selbstständigkeit zu sichern. Wir sprechen außerdem darüber, - wie sich der Zustand Ihrer Muskulatur einfach testen lässt, - wie Muskeln nicht nur den Körper, sondern auch Gehirn und Psyche beeinflussen, - wie optimale Trainingsstrategien – von Kraftübungen bis Ausdauer – aussehen, - wie körperliche Aktivität das Risiko für viele Krebserkrankungen senken kann, - wie richtige Eiweißversorgung und Ernährung Muskelaufbau sowie -erhalt fördern. Der klare Appell: „Gesundheit kann man sich nicht erkaufen, man muss sie sich erarbeiten.“ Denn Muskeln entwickeln sich nur, wenn wir sie aktiv nutzen und trainieren. "Der ERCM Medizin Podcast" Social & Webseite: Instagram: https://www.instagram.com/ercm.podcast/ TikTok: https://www.tiktok.com/@ercm.podcast?lang=de-DE X (Twitter): https://twitter.com/ERCMPodcast Webseite: www.erc-munich.com Kontakt: podcast@erc-munich.com Prof. Dr. Ingo Froböse: Webseite: https://www.ingo-froboese.de/ Bücher: https://www.ingo-froboese.de/buecher/ YouTube: @formelfroboese Über das ERCM: Im Europäischen Radiochirurgie Centrum München (ERCM) setzen wir seit über 20 Jahren auf präzise Tumortherapien: hochmoderne https://www.youtube-nocookie.com/embed/pKupQOqYDww 3934 2025-09-15T06:00:46.000Z 2026-10-22T18:32:07.422Z https://longevityharbor.com/de/watch/pKupQOqYDww Nr. 1 Muskel-Experte: Das Geheimnis für starke Muskeln in jedem Alter | Prof. Ingo Froböse https://i.ytimg.com/vi/pKupQOqYDww/hqdefault.jpg Die Muskulatur ist unser größtes Stoffwechselorgan – entscheidend für Gesundheit, Leistungsfähigkeit und ein langes Leben. Und doch wird ihre Bedeutung noch immer unterschätzt. Darüber sprechen wir mit Prof. Dr. Ingo Froböse (@formelfroboese), einem der bekanntesten Sportwissenschaftler Deutschlands, Universitätsprofessor an der Deutschen Sporthochschule Köln und Autor von über 40 Büchern. Seit Jahrzehnten erforscht er, wie Bewegung, Prävention und Gesundheit zusammenwirken. Im ERCM Medizin Podcast erklärt er, warum Muskulatur heute als endokrines Organ gilt, welche Botenstoffe aktive Muskeln ausschütten (Myokine) – und wie diese unser Immun-, Hormon- und Herz-Kreislauf-System beeinflussen. Ingo Froböse zeigt auch, weshalb Muskelabbau (Sarkopenie) kein unausweichliches Schicksal ist – und wie Muskeln in jedem Alter gezielt aufgebaut und erhalten werden können, um Vitalität und Selbstständigkeit zu sichern. Wir sprechen außerdem darüber, - wie sich der Zustand Ihrer Muskulatur einfach testen lässt, - wie Muskeln nicht nur den Körper, sondern auch Gehirn und Psyche beeinflussen, - wie optimale Trainingsstrategien – von Kraftübungen bis Ausdauer – aussehen, - wie körperliche Aktivität das Risiko für viele Krebserkrankungen senken kann, - wie richtige Eiweißversorgung und Ernährung Muskelaufbau sowie -erhalt fördern. Der klare Appell: „Gesundheit kann man sich nicht erkaufen, man muss sie sich erarbeiten.“ Denn Muskeln entwickeln sich nur, wenn wir sie aktiv nutzen und trainieren. "Der ERCM Medizin Podcast" Social & Webseite: Instagram: https://www.instagram.com/ercm.podcast/ TikTok: https://www.tiktok.com/@ercm.podcast?lang=de-DE X (Twitter): https://twitter.com/ERCMPodcast Webseite: www.erc-munich.com Kontakt: podcast@erc-munich.com Prof. Dr. Ingo Froböse: Webseite: https://www.ingo-froboese.de/ Bücher: https://www.ingo-froboese.de/buecher/ YouTube: @formelfroboese Über das ERCM: Im Europäischen Radiochirurgie Centrum München (ERCM) setzen wir seit über 20 Jahren auf präzise Tumortherapien: hochmoderne https://www.youtube-nocookie.com/embed/pKupQOqYDww 3934 2025-09-15T06:00:46.000Z 2026-10-22T18:32:07.422Z https://longevityharbor.com/en/watch/pZX8ikmWvEU Female-Specific Exercise & Nutrition for Health, Performance & Longevity | Dr. Stacy Sims https://i.ytimg.com/vi/pZX8ikmWvEU/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this episode, my guest is Dr. Stacy Sims, Ph.D., an exercise physiologist, nutrition scientist, and expert in female-specific nutrition and training for health, performance, and longevity. We discuss which exercise and nutrition protocols are ideal for women based on their age and particular goals. We discuss whether women should train fasted, when and what to eat pre- and post-training, and how the menstrual cycle impacts training and nutrition needs. We also explain how to use a combination of resistance, high-intensity, and sprint interval training to effectively improve body composition, hormones, and cardiometabolic health, offset cognitive decline, and promote longevity. We also discuss supplements and caffeine, the unique sleep needs of women based on age, whether women should use deliberate cold exposure, and how saunas can improve symptoms of hot flashes and benefit athletic performance. Dr. Sims challenges common misconceptions about women’s health and fitness and explains why certain types of cardio, caloric restriction, and low-protein diets can be harmful to women’s metabolic health. Listeners will learn a wealth of actionable information on how to improve their training and nutrition to enhance their health and how to age with greater ability, mobility, and vitality. Access the full show notes for this episode: https://www.hubermanlab.com/episode/dr-stacy-sims-female-specific-exercise-nutrition-for-health-performance-longevity Pre-order Andrew's new book, Protocols: https://protocolsbook.com *Thank you to our sponsors* AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman Eight Sleep: https://eightsleep.com/huberman Waking Up: https://wakingup.com/huberman *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https: https://www.youtube-nocookie.com/embed/pZX8ikmWvEU 8918 2024-07-22T12:00:53.000Z 2026-10-22T19:04:44.807Z https://longevityharbor.com/de/watch/pZX8ikmWvEU Female-Specific Exercise & Nutrition for Health, Performance & Longevity | Dr. Stacy Sims https://i.ytimg.com/vi/pZX8ikmWvEU/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event In this episode, my guest is Dr. Stacy Sims, Ph.D., an exercise physiologist, nutrition scientist, and expert in female-specific nutrition and training for health, performance, and longevity. We discuss which exercise and nutrition protocols are ideal for women based on their age and particular goals. We discuss whether women should train fasted, when and what to eat pre- and post-training, and how the menstrual cycle impacts training and nutrition needs. We also explain how to use a combination of resistance, high-intensity, and sprint interval training to effectively improve body composition, hormones, and cardiometabolic health, offset cognitive decline, and promote longevity. We also discuss supplements and caffeine, the unique sleep needs of women based on age, whether women should use deliberate cold exposure, and how saunas can improve symptoms of hot flashes and benefit athletic performance. Dr. Sims challenges common misconceptions about women’s health and fitness and explains why certain types of cardio, caloric restriction, and low-protein diets can be harmful to women’s metabolic health. Listeners will learn a wealth of actionable information on how to improve their training and nutrition to enhance their health and how to age with greater ability, mobility, and vitality. Access the full show notes for this episode: https://www.hubermanlab.com/episode/dr-stacy-sims-female-specific-exercise-nutrition-for-health-performance-longevity Pre-order Andrew's new book, Protocols: https://protocolsbook.com *Thank you to our sponsors* AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman Eight Sleep: https://eightsleep.com/huberman Waking Up: https://wakingup.com/huberman *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https: https://www.youtube-nocookie.com/embed/pZX8ikmWvEU 8918 2024-07-22T12:00:53.000Z 2026-10-22T19:04:44.807Z https://longevityharbor.com/en/watch/paW7sU_bufs Gamifying Longevity Research | The DeSci Podcast https://i.ytimg.com/vi/paW7sU_bufs/hqdefault.jpg In a recent episode of The DeSci Podcast, we welcomed Krister Kauppi, founder Rapamycin Longevity Lab, and Dr Mitchell Lee, CEO and co-founder at Ora Biomedical. The conversation focused on two major themes: how to accelerate research in the longevity space and the potential of gamification and decentralized incentives to push longevity research forward. https://www.youtube-nocookie.com/embed/paW7sU_bufs 3938 2024-10-16T15:25:14.000Z 2026-10-22T19:32:34.374Z https://longevityharbor.com/de/watch/paW7sU_bufs Gamifying Longevity Research | The DeSci Podcast https://i.ytimg.com/vi/paW7sU_bufs/hqdefault.jpg In a recent episode of The DeSci Podcast, we welcomed Krister Kauppi, founder Rapamycin Longevity Lab, and Dr Mitchell Lee, CEO and co-founder at Ora Biomedical. The conversation focused on two major themes: how to accelerate research in the longevity space and the potential of gamification and decentralized incentives to push longevity research forward. https://www.youtube-nocookie.com/embed/paW7sU_bufs 3938 2024-10-16T15:25:14.000Z 2026-10-22T19:32:34.374Z https://longevityharbor.com/en/watch/pgEZNF4cHcI HIV and Aging: A human retrovirus that can advance the Geroscience https://i.ytimg.com/vi/pgEZNF4cHcI/hqdefault.jpg Michael Corley, PhD, MA (he/him) Associate Professor Division of Geriatrics, Gerontology and Palliative Care Department of Medicine University of California San Diego https://www.youtube-nocookie.com/embed/pgEZNF4cHcI 3676 2025-10-13T18:33:45.000Z 2026-10-22T18:32:11.550Z https://longevityharbor.com/de/watch/pgEZNF4cHcI HIV and Aging: A human retrovirus that can advance the Geroscience https://i.ytimg.com/vi/pgEZNF4cHcI/hqdefault.jpg Michael Corley, PhD, MA (he/him) Associate Professor Division of Geriatrics, Gerontology and Palliative Care Department of Medicine University of California San Diego https://www.youtube-nocookie.com/embed/pgEZNF4cHcI 3676 2025-10-13T18:33:45.000Z 2026-10-22T18:32:11.550Z https://longevityharbor.com/en/watch/pjqzNOMYX7o Video description: long-term intermittent fasting and aging claims https://i.ytimg.com/vi/pjqzNOMYX7o/hqdefault.jpg The description of a Core Health video says long-term intermittent fasting affects cellular repair, autophagy and biological aging, and lists fat burning, growth hormone, brain focus and inflammation as topics. No study results are given. https://www.youtube-nocookie.com/embed/pjqzNOMYX7o 906 2026-01-25T00:30:59.000Z 2026-10-23T02:46:20.005Z https://longevityharbor.com/de/watch/pjqzNOMYX7o Videobeschreibung: Langzeit-Intervallfasten und Alternsaussagen https://i.ytimg.com/vi/pjqzNOMYX7o/hqdefault.jpg Die Beschreibung eines Core-Health-Videos behauptet, Langzeit-Intervallfasten beeinflusse Zellreparatur, Autophagie und biologisches Altern, und nennt Fettverbrennung, Wachstumshormon, Hirnleistung und Entzündung als Themen. Studienergebnisse werden nicht genannt. https://www.youtube-nocookie.com/embed/pjqzNOMYX7o 906 2026-01-25T00:30:59.000Z 2026-10-23T02:46:20.005Z https://longevityharbor.com/en/watch/pkL0vLuO0lc Hafer & Hülsenfrüchte Experten Tipps zur gesunden Ernährung! #hafer #tipps #gesundes https://i.ytimg.com/vi/pkL0vLuO0lc/hqdefault.jpg Hafer & Hülsenfrüchte Experten Tipps zur gesunden Ernährung! #hafer #tipps #gesundes https://www.youtube-nocookie.com/embed/pkL0vLuO0lc 157 2025-08-17T18:00:45.000Z 2026-10-22T18:43:10.918Z https://longevityharbor.com/de/watch/pkL0vLuO0lc Hafer & Hülsenfrüchte Experten Tipps zur gesunden Ernährung! #hafer #tipps #gesundes https://i.ytimg.com/vi/pkL0vLuO0lc/hqdefault.jpg Hafer & Hülsenfrüchte Experten Tipps zur gesunden Ernährung! #hafer #tipps #gesundes https://www.youtube-nocookie.com/embed/pkL0vLuO0lc 157 2025-08-17T18:00:45.000Z 2026-10-22T18:43:10.918Z https://longevityharbor.com/en/watch/q-H_eX97M8Q Can Calorie Restriction Slow Aging? – Side Effects of Low Calorie Diet – Dr.Berg https://i.ytimg.com/vi/q-H_eX97M8Q/hqdefault.jpg Check my FREE Calorie Burning Cheat Sheet 👉 https://drbrg.co/3yVOoIq Just so you know, my full line of high-quality supplements is available on Amazon — search Dr. Berg Supplements. For more info on health-related topics, go here: http://bit.ly/2Fu9cYR Take Dr. Berg's Free Keto Mini-Course: http://pxlme.me/-i717vtY or go here: http://bit.ly/2RmaFDS Overview of Healthy Ketogenic Diet and Intermittent Fasting: https://www.youtube.com/watch?v=vMZfyEy_jpI https://www.youtube.com/watch?v=mBqpaAKtnXE https://www.youtube.com/watch?v=3dHcT1-K-tw Download Keto Essentials http://bit.ly/2DH0d6o Today, we’re going to talk about calorie restriction. Can calorie restriction slow aging? You may have heard before that counting calories can have anti-aging effects. But, that conflicts with all of the people who have tried a low-calorie diet in the past.  It has been proven that the more you diet and lower your calories, the more you end up gaining the weight back. It also destroys your metabolism over time. If you’re doing a low-calorie diet with high carbs, you’re going to keep your blood sugars going up and down. If you do a low-calorie diet with low fat, you’re going to be hungry, and it’s not sustainable.  The benefit of calorie restriction is epigenetics.  The two epigenetic triggers for the benefits of calorie restriction are lowering glucose and lowering insulin. The benefits aren’t coming from restricting calories. The benefits are coming from restricting glucose and insulin. The other problem with a low-calorie diet is that people lower their nutrients. This can create nutrient deficiencies which can lead to all kinds of problems. I don’t recommend calorie restriction. I do recommend restricting glucose which will indirectly lower your insulin. I recommend the healthy ketogenic diet and intermittent fasting. This is a low carb, moderate protein, high-fat diet that is comfortable, sustainable, and provides a ton of health benefits including anti-aging effects. Dr. Eric Berg DC Bio: Dr. Berg, 56 years of https://www.youtube-nocookie.com/embed/q-H_eX97M8Q 323 2019-09-16T12:00:11.000Z 2026-10-22T17:43:38.471Z https://longevityharbor.com/de/watch/q-H_eX97M8Q Can Calorie Restriction Slow Aging? – Side Effects of Low Calorie Diet – Dr.Berg https://i.ytimg.com/vi/q-H_eX97M8Q/hqdefault.jpg Check my FREE Calorie Burning Cheat Sheet 👉 https://drbrg.co/3yVOoIq Just so you know, my full line of high-quality supplements is available on Amazon — search Dr. Berg Supplements. For more info on health-related topics, go here: http://bit.ly/2Fu9cYR Take Dr. Berg's Free Keto Mini-Course: http://pxlme.me/-i717vtY or go here: http://bit.ly/2RmaFDS Overview of Healthy Ketogenic Diet and Intermittent Fasting: https://www.youtube.com/watch?v=vMZfyEy_jpI https://www.youtube.com/watch?v=mBqpaAKtnXE https://www.youtube.com/watch?v=3dHcT1-K-tw Download Keto Essentials http://bit.ly/2DH0d6o Today, we’re going to talk about calorie restriction. Can calorie restriction slow aging? You may have heard before that counting calories can have anti-aging effects. But, that conflicts with all of the people who have tried a low-calorie diet in the past.  It has been proven that the more you diet and lower your calories, the more you end up gaining the weight back. It also destroys your metabolism over time. If you’re doing a low-calorie diet with high carbs, you’re going to keep your blood sugars going up and down. If you do a low-calorie diet with low fat, you’re going to be hungry, and it’s not sustainable.  The benefit of calorie restriction is epigenetics.  The two epigenetic triggers for the benefits of calorie restriction are lowering glucose and lowering insulin. The benefits aren’t coming from restricting calories. The benefits are coming from restricting glucose and insulin. The other problem with a low-calorie diet is that people lower their nutrients. This can create nutrient deficiencies which can lead to all kinds of problems. I don’t recommend calorie restriction. I do recommend restricting glucose which will indirectly lower your insulin. I recommend the healthy ketogenic diet and intermittent fasting. This is a low carb, moderate protein, high-fat diet that is comfortable, sustainable, and provides a ton of health benefits including anti-aging effects. Dr. Eric Berg DC Bio: Dr. Berg, 56 years of https://www.youtube-nocookie.com/embed/q-H_eX97M8Q 323 2019-09-16T12:00:11.000Z 2026-10-22T17:43:38.471Z https://longevityharbor.com/en/watch/q1Xh1mrLhUc Talk on inactive X chromosome stability and sex-biased disease https://i.ytimg.com/vi/q1Xh1mrLhUc/hqdefault.jpg The description says Dr. Daniel Andergassen's Milan Longevity Summit 2026 talk covers the inactive X chromosome, its stability over life, and possible links to ageing and sex-biased disease. https://www.youtube-nocookie.com/embed/q1Xh1mrLhUc 1357 2026-08-08T11:14:05.000Z 2026-10-22T23:08:32.215Z https://longevityharbor.com/de/watch/q1Xh1mrLhUc Vortrag zur Stabilität des inaktiven X-Chromosoms und geschlechtsspezifischen Krankheiten https://i.ytimg.com/vi/q1Xh1mrLhUc/hqdefault.jpg Laut Beschreibung behandelt der Vortrag von Dr. Daniel Andergassen beim Milan Longevity Summit 2026 das inaktive X-Chromosom, seine Stabilität im Lebensverlauf und mögliche Bezüge zu Altern und geschlechtsspezifischen Krankheiten. https://www.youtube-nocookie.com/embed/q1Xh1mrLhUc 1357 2026-08-08T11:14:05.000Z 2026-10-22T23:08:32.215Z https://longevityharbor.com/en/watch/q2IYP7w5NhU Video description: epigenetic age, executive lifestyle and an 8-week reversal study https://i.ytimg.com/vi/q2IYP7w5NhU/hqdefault.jpg The description says biological age is measured with epigenetic clocks, that a 48-year-old executive's test showed 57, and that one study reported 3.23 years of reversal in eight weeks through lifestyle intervention alone. These are the creator's claims; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/q2IYP7w5NhU 793 2026-03-26T07:00:43.000Z 2026-10-23T01:51:50.045Z https://longevityharbor.com/de/watch/q2IYP7w5NhU Videobeschreibung: epigenetisches Alter, Führungskräfte-Lebensstil und eine 8-Wochen-Studie https://i.ytimg.com/vi/q2IYP7w5NhU/hqdefault.jpg Laut Beschreibung wird das biologische Alter mit epigenetischen Uhren gemessen, ein Test bei einem 48-jährigen Führungskräft zeigte 57, und eine Studie berichtete über 3,23 Jahre Rückwärtsalterung in acht Wochen allein durch Lebensstil-Intervention. Dies sind Angaben des Erstellers; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/q2IYP7w5NhU 793 2026-03-26T07:00:43.000Z 2026-10-23T01:51:50.045Z https://longevityharbor.com/en/watch/q4Os75kYmm4 Rapamycin: Anti-Aging Molecule #longevity #biohacking #rapamycin https://i.ytimg.com/vi/q4Os75kYmm4/hqdefault.jpg What is Rapamycin, and why are longevity scientists so excited about it? Originally used for organ transplant patients, Rapamycin is now being studied for its potential to slow aging, reduce inflammation, and improve cellular repair. It works by regulating a powerful pathway called mTOR, if you're unfamiliar, check out my video on mTOR fundamentals for the full breakdown: https://www.youtube.com/shorts/2ZG0SkJDL6k This video explains what Rapamycin is, what it does, how it's being studied, and why it may become one of the most important compounds in aging science. Stay informed, stay future-ready. Neoradus. https://www.youtube-nocookie.com/embed/q4Os75kYmm4 156 2025-06-22T13:48:56.000Z 2026-10-22T17:43:41.093Z https://longevityharbor.com/de/watch/q4Os75kYmm4 Rapamycin: Anti-Aging Molecule #longevity #biohacking #rapamycin https://i.ytimg.com/vi/q4Os75kYmm4/hqdefault.jpg What is Rapamycin, and why are longevity scientists so excited about it? Originally used for organ transplant patients, Rapamycin is now being studied for its potential to slow aging, reduce inflammation, and improve cellular repair. It works by regulating a powerful pathway called mTOR, if you're unfamiliar, check out my video on mTOR fundamentals for the full breakdown: https://www.youtube.com/shorts/2ZG0SkJDL6k This video explains what Rapamycin is, what it does, how it's being studied, and why it may become one of the most important compounds in aging science. Stay informed, stay future-ready. Neoradus. https://www.youtube-nocookie.com/embed/q4Os75kYmm4 156 2025-06-22T13:48:56.000Z 2026-10-22T17:43:41.093Z https://longevityharbor.com/en/watch/q5Ssmb_iSSA Video description on telomeres, senescent cells and senolytics https://i.ytimg.com/vi/q5Ssmb_iSSA/hqdefault.jpg The creator says the video covers cellular aging: telomere shortening, DNA damage, apoptosis, BCL 2, cellular senescence and SASP, and introduces senolytics as an emerging approach to selectively eliminate senescent cells. https://www.youtube-nocookie.com/embed/q5Ssmb_iSSA 120 2026-09-12T05:32:25.000Z 2026-10-22T22:18:09.471Z https://longevityharbor.com/de/watch/q5Ssmb_iSSA Videobeschreibung zu Telomeren, seneszenten Zellen und Senolytika https://i.ytimg.com/vi/q5Ssmb_iSSA/hqdefault.jpg Der Ersteller sagt, das Video behandele zelluläres Altern: Telomerverkürzung, DNA-Schäden, Apoptose, BCL 2, zelluläre Seneszenz und SASP, und stelle Senolytika als neuen Ansatz vor, seneszente Zellen gezielt zu beseitigen. https://www.youtube-nocookie.com/embed/q5Ssmb_iSSA 120 2026-09-12T05:32:25.000Z 2026-10-22T22:18:09.471Z https://longevityharbor.com/en/watch/q5ZN_mT-xbw Lifespan Extension With Calorie Restriction, Fasting, And Circadian Alignment https://i.ytimg.com/vi/q5ZN_mT-xbw/hqdefault.jpg Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD Discount Links: NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/ Use Code: ConquerAging At Checkout Green Tea: https://www.ochaandco.com/?ref=conqueraging Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten Epigenetic Testing: Trudiagnostic.pxf.io/R55XDv Use Code: CONQUERAGING At-Home Blood Testing: https://getquantify.io/mlustgarten Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack= If you'd like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/ __________________________________________________________________________________________________ Papers referenced in the video: Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice https://www.nature.com/articles/s42255-021-00466-9 Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice https://pubmed.ncbi.nlm.nih.gov/35511946/ https://www.youtube-nocookie.com/embed/q5ZN_mT-xbw 455 2022-08-07T11:00:11.000Z 2026-10-22T17:43:38.455Z https://longevityharbor.com/de/watch/q5ZN_mT-xbw Lifespan Extension With Calorie Restriction, Fasting, And Circadian Alignment https://i.ytimg.com/vi/q5ZN_mT-xbw/hqdefault.jpg Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD Discount Links: NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/ Use Code: ConquerAging At Checkout Green Tea: https://www.ochaandco.com/?ref=conqueraging Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten Epigenetic Testing: Trudiagnostic.pxf.io/R55XDv Use Code: CONQUERAGING At-Home Blood Testing: https://getquantify.io/mlustgarten Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack= If you'd like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/ __________________________________________________________________________________________________ Papers referenced in the video: Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice https://www.nature.com/articles/s42255-021-00466-9 Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice https://pubmed.ncbi.nlm.nih.gov/35511946/ https://www.youtube-nocookie.com/embed/q5ZN_mT-xbw 455 2022-08-07T11:00:11.000Z 2026-10-22T17:43:38.455Z https://longevityharbor.com/en/watch/q7QD9XVXTbA Your Body’s Master Clock: A Deep Dive into Circadian Coordination https://i.ytimg.com/vi/q7QD9XVXTbA/hqdefault.jpg Every cell in your body runs on a clock and when that rhythm breaks, so does everything else. As a Functional Registered Nutritionist and circadian biology researcher, I’ve spent years studying the connection between internal timing and health. But this new paper truly reframed how I think about ageing. It confirmed what many of us in the field have suspected: from our liver to our lungs, each organ follows its own rhythm (Wang J. et al., 2025). And at the centre of it all sits the SCN, our brain’s master clock, synchronised to daylight and constantly sending timing signals across the body to the liver, kidneys, pancreas, even the prostate (Zhu W-Z. et al., 2023). When this rhythm unravels, the effects are systemic. DNA repair slows. Inflammation rises. Cellular ageing accelerates (López-Otín C., Pietrocola F. et al., 2023). It’s not just about how much we sleep. It’s about when our body carries out vital tasks like immune regulation and hormone release (Wang J. et al., 2025). The study also highlights the role of proteins like BMAL1 and CLOCK, which regulate gene activity in near 24-hour cycles, influencing everything from inflammation to immune strength (Wang J. et al., 2025). They even mapped out how core circadian genes and their SNPs interact with tumour pathways, a major leap forward in our understanding of circadian health and cancer (Wang J. et al., 2025). Improving health isn’t just about what we do, it’s about when we do it (López-Otín C., Blasco M. et al., 2023). If you want to learn how to protect your circadian rhythms and age with greater resilience, read my latest blog post. https://www.youtube-nocookie.com/embed/q7QD9XVXTbA 114 2025-07-30T18:54:29.000Z 2026-10-22T18:54:02.073Z https://longevityharbor.com/de/watch/q7QD9XVXTbA Your Body’s Master Clock: A Deep Dive into Circadian Coordination https://i.ytimg.com/vi/q7QD9XVXTbA/hqdefault.jpg Every cell in your body runs on a clock and when that rhythm breaks, so does everything else. As a Functional Registered Nutritionist and circadian biology researcher, I’ve spent years studying the connection between internal timing and health. But this new paper truly reframed how I think about ageing. It confirmed what many of us in the field have suspected: from our liver to our lungs, each organ follows its own rhythm (Wang J. et al., 2025). And at the centre of it all sits the SCN, our brain’s master clock, synchronised to daylight and constantly sending timing signals across the body to the liver, kidneys, pancreas, even the prostate (Zhu W-Z. et al., 2023). When this rhythm unravels, the effects are systemic. DNA repair slows. Inflammation rises. Cellular ageing accelerates (López-Otín C., Pietrocola F. et al., 2023). It’s not just about how much we sleep. It’s about when our body carries out vital tasks like immune regulation and hormone release (Wang J. et al., 2025). The study also highlights the role of proteins like BMAL1 and CLOCK, which regulate gene activity in near 24-hour cycles, influencing everything from inflammation to immune strength (Wang J. et al., 2025). They even mapped out how core circadian genes and their SNPs interact with tumour pathways, a major leap forward in our understanding of circadian health and cancer (Wang J. et al., 2025). Improving health isn’t just about what we do, it’s about when we do it (López-Otín C., Blasco M. et al., 2023). If you want to learn how to protect your circadian rhythms and age with greater resilience, read my latest blog post. https://www.youtube-nocookie.com/embed/q7QD9XVXTbA 114 2025-07-30T18:54:29.000Z 2026-10-22T18:54:02.073Z https://longevityharbor.com/en/watch/q9-mLMXjcH4 Fasting VS Calorie Restriction (dieting): study finds Health, Longevity Benefits are Different https://i.ytimg.com/vi/q9-mLMXjcH4/hqdefault.jpg A team of scientist conducted a series of laboratory studies to disentangle the benefits of fasting from that of calorie restriction. In brief, they found many of the benefits ascribed to calorie restriction actually depend on simultaneous fasting. Save your seat for the Blood Work MasterClass: https://courses.highintensityhealth.com/store/hgwDdo2p Links to research: https://bit.ly/3wF4eSL Blood work cheat sheet: https://bit.ly/3dyy4zM Support Sleep and Relaxation this updated Myo Relax by MYOXCIENCE Nutrition: https://bit.ly/Inositol-theanine-magnesium-drink Save with code podcast at checkout -------------Sleep & Camera Tools You NEED!----------------------- Best Sleep Mask: http://bit.ly/2AIVbDV Blue Blocking Glasses: http://bit.ly/blueblox A Metabolism Book Should Have:https://amzn.to/2jUiAh5 Best Mouth Tape (Nexcare): https://amzn.to/31qJayh Red Headlamp (wear this at night around your house): https://amzn.to/2YzMGtw Breath Right Strips: https://amzn.to/31t5VSl -----------------------------------------Show Notes-------------------------------------- 0:00 Intro 0:05 Shared Features of Fasting and Calorie Restriction 0:23 New Study 1:23 Big Omission from Calorie Restriction Data 2:40 Blood Work MasterClass 3:53 Testing Fasting VS Calorie Restriction study details 5:53 Metabolic Rate slows 6:40 Fuel Switch with fasting 7:23 Insulin, Glucagon and fat oxidation 08:54 Metabolic profiling of different fasting patterns 10:38 Experiment Number 2 11:03 Lifespan extension in fasting VS CR VS Ad Lib 13:43 Match Carbohydrate intake with exercise 14:10 TRF Feeding pattern practical tips https://www.youtube-nocookie.com/embed/q9-mLMXjcH4 991 2021-11-12T18:37:00.000Z 2026-10-22T17:43:38.393Z https://longevityharbor.com/de/watch/q9-mLMXjcH4 Fasting VS Calorie Restriction (dieting): study finds Health, Longevity Benefits are Different https://i.ytimg.com/vi/q9-mLMXjcH4/hqdefault.jpg A team of scientist conducted a series of laboratory studies to disentangle the benefits of fasting from that of calorie restriction. In brief, they found many of the benefits ascribed to calorie restriction actually depend on simultaneous fasting. Save your seat for the Blood Work MasterClass: https://courses.highintensityhealth.com/store/hgwDdo2p Links to research: https://bit.ly/3wF4eSL Blood work cheat sheet: https://bit.ly/3dyy4zM Support Sleep and Relaxation this updated Myo Relax by MYOXCIENCE Nutrition: https://bit.ly/Inositol-theanine-magnesium-drink Save with code podcast at checkout -------------Sleep & Camera Tools You NEED!----------------------- Best Sleep Mask: http://bit.ly/2AIVbDV Blue Blocking Glasses: http://bit.ly/blueblox A Metabolism Book Should Have:https://amzn.to/2jUiAh5 Best Mouth Tape (Nexcare): https://amzn.to/31qJayh Red Headlamp (wear this at night around your house): https://amzn.to/2YzMGtw Breath Right Strips: https://amzn.to/31t5VSl -----------------------------------------Show Notes-------------------------------------- 0:00 Intro 0:05 Shared Features of Fasting and Calorie Restriction 0:23 New Study 1:23 Big Omission from Calorie Restriction Data 2:40 Blood Work MasterClass 3:53 Testing Fasting VS Calorie Restriction study details 5:53 Metabolic Rate slows 6:40 Fuel Switch with fasting 7:23 Insulin, Glucagon and fat oxidation 08:54 Metabolic profiling of different fasting patterns 10:38 Experiment Number 2 11:03 Lifespan extension in fasting VS CR VS Ad Lib 13:43 Match Carbohydrate intake with exercise 14:10 TRF Feeding pattern practical tips https://www.youtube-nocookie.com/embed/q9-mLMXjcH4 991 2021-11-12T18:37:00.000Z 2026-10-22T17:43:38.393Z https://longevityharbor.com/en/watch/q9BTVfSuoG4 Video description: gut health beyond microbiome composition, with GI-MAP and StoolOMX discussed https://i.ytimg.com/vi/q9BTVfSuoG4/hqdefault.jpg In the description, Dr. Kara Fitzgerald and Dr. Tom Fabian discuss gut health as more than which microbes are present, linking it to digestion, immune balance, gut barrier integrity and metabolic function, and present GI-MAP and the StoolOMX add-on as functional profiling tools. https://www.youtube-nocookie.com/embed/q9BTVfSuoG4 3665 2026-05-20T19:15:33.000Z 2026-10-23T00:37:39.396Z https://longevityharbor.com/de/watch/q9BTVfSuoG4 Videobeschreibung: Darmgesundheit jenseits der Mikrobiom-Zusammensetzung, GI-MAP und StoolOMX erörte https://i.ytimg.com/vi/q9BTVfSuoG4/hqdefault.jpg In der Beschreibung erörtern Dr. Kara Fitzgerald und Dr. Tom Fabian Darmgesundheit als mehr als die Frage, welche Mikroben vorhanden sind, und verknüpfen sie mit Verdauung, Immunbalance, Darmbarriere und Stoffwechselfunktion; GI-MAP und das StoolOMX-Add-on werden als funktionelle Profilierungswerkzeuge vorgestellt. https://www.youtube-nocookie.com/embed/q9BTVfSuoG4 3665 2026-05-20T19:15:33.000Z 2026-10-23T00:37:39.396Z https://longevityharbor.com/en/watch/qAop6GeYF2M Longevity-Expertin: Wie wir unser biologisches Alter zurückdrehen können! | Dr. Simone Koch https://i.ytimg.com/vi/qAop6GeYF2M/hqdefault.jpg Können wir unser biologisches Alter tatsächlich beeinflussen? Warum altern manche Menschen schneller, während andere auch im hohen Alter jugendlich und vital wirken? – Und wie können wir den Alterungsprozess positiv beeinflussen? Dr. med. Simone Koch, Fachärztin für Gynäkologie und Geburtshilfe mit Zusatzqualifikationen in Ernährungs- und Umweltmedizin sowie Spezialisierung auf Longevity-Medizin, gibt in dieser Folge des ERCM Medizin Podcast faszinierende Einblicke in die neuesten wissenschaftlichen Erkenntnisse zum gesunden Altern. Sie erklärt, wie epigenetische Mechanismen und Umweltfaktoren unsere Gene prägen – und warum wir heute wissen: Gesundheit und die Lebensspanne liegen weitaus stärker in unserer eigenen Hand, als lange angenommen wurde. Besonders spannend: Dr. Koch beleuchtet entscheidende Lebensphasen – meist um Mitte 40 sowie um das 60. Lebensjahr –, in denen sich Körper, Vitalität und Wohlbefinden oft spürbar verändern. Sie zeigt konkrete Wege auf, wie jeder diese Phasen aktiv gestalten und optimal für langfristige Gesundheit nutzen kann. Individuelle Longevity-Strategien spielen dabei eine zentrale Rolle: Von der präzisen Bestimmung des biologischen Alters über die Optimierung des Mikronährstoffbedarfs bis hin zu aktuellen Kontroversen rund um Abnehmspritzen wie Ozempic. Simone Koch räumt mit gängigen Mythen auf, teilt persönliche Longevity-Routinen und erklärt, warum ein gezieltes Krafttraining als wichtigster Prädiktor für Langlebigkeit gilt. Kalorienrestriktion, Nahrungsergänzungen oder KI als Longevity-Coach? Sie erfahren, welche Ansätze wirklich sinnvoll sind und welche nicht, um das biologische Alter zu senken – und die persönliche Lebensqualität nachhaltig zu steigern. Wir sprechen über: - Warum unser biologisches Alter nicht festgeschrieben ist - Die entscheidenden Altersphasen um 44 und 60 Jahre - Epigenetik: Wie Umwelt und Lebensstil unsere Gene beeinflussen - Krafttraining als stärkster Prädiktor für gesundes Altern - Mythen und Trends – von Mikronährstoffen bis Abnehmspritzen De https://www.youtube-nocookie.com/embed/qAop6GeYF2M 5878 2025-08-18T06:00:39.000Z 2026-10-22T17:11:30.661Z https://longevityharbor.com/de/watch/qAop6GeYF2M Longevity-Expertin: Wie wir unser biologisches Alter zurückdrehen können! | Dr. Simone Koch https://i.ytimg.com/vi/qAop6GeYF2M/hqdefault.jpg Können wir unser biologisches Alter tatsächlich beeinflussen? Warum altern manche Menschen schneller, während andere auch im hohen Alter jugendlich und vital wirken? – Und wie können wir den Alterungsprozess positiv beeinflussen? Dr. med. Simone Koch, Fachärztin für Gynäkologie und Geburtshilfe mit Zusatzqualifikationen in Ernährungs- und Umweltmedizin sowie Spezialisierung auf Longevity-Medizin, gibt in dieser Folge des ERCM Medizin Podcast faszinierende Einblicke in die neuesten wissenschaftlichen Erkenntnisse zum gesunden Altern. Sie erklärt, wie epigenetische Mechanismen und Umweltfaktoren unsere Gene prägen – und warum wir heute wissen: Gesundheit und die Lebensspanne liegen weitaus stärker in unserer eigenen Hand, als lange angenommen wurde. Besonders spannend: Dr. Koch beleuchtet entscheidende Lebensphasen – meist um Mitte 40 sowie um das 60. Lebensjahr –, in denen sich Körper, Vitalität und Wohlbefinden oft spürbar verändern. Sie zeigt konkrete Wege auf, wie jeder diese Phasen aktiv gestalten und optimal für langfristige Gesundheit nutzen kann. Individuelle Longevity-Strategien spielen dabei eine zentrale Rolle: Von der präzisen Bestimmung des biologischen Alters über die Optimierung des Mikronährstoffbedarfs bis hin zu aktuellen Kontroversen rund um Abnehmspritzen wie Ozempic. Simone Koch räumt mit gängigen Mythen auf, teilt persönliche Longevity-Routinen und erklärt, warum ein gezieltes Krafttraining als wichtigster Prädiktor für Langlebigkeit gilt. Kalorienrestriktion, Nahrungsergänzungen oder KI als Longevity-Coach? Sie erfahren, welche Ansätze wirklich sinnvoll sind und welche nicht, um das biologische Alter zu senken – und die persönliche Lebensqualität nachhaltig zu steigern. Wir sprechen über: - Warum unser biologisches Alter nicht festgeschrieben ist - Die entscheidenden Altersphasen um 44 und 60 Jahre - Epigenetik: Wie Umwelt und Lebensstil unsere Gene beeinflussen - Krafttraining als stärkster Prädiktor für gesundes Altern - Mythen und Trends – von Mikronährstoffen bis Abnehmspritzen De https://www.youtube-nocookie.com/embed/qAop6GeYF2M 5878 2025-08-18T06:00:39.000Z 2026-10-22T17:11:30.661Z https://longevityharbor.com/en/watch/qF42pnGei6g Imagine We Cured Death. Here's Why Immortal Humans Still Couldn't Cross the Galaxy https://i.ytimg.com/vi/qF42pnGei6g/hqdefault.jpg Imagine we cured death. Not slowed it — cured it. The telomeres are stable. The mitochondria repair themselves. The immune system holds indefinitely. Every clinical trial confirms it. You will not age. Not today, not in ten thousand years. Now someone runs the numbers on what that means for crossing the galaxy. The Milky Way is 100,000 light-years in diameter. At the speed of light — which nothing with mass can reach — crossing it takes 100,000 years. At ten percent of light speed, the most optimistic estimate for any propulsion system that uses physics we actually understand, it takes one million years. One million years is three times the total age of Homo sapiens. The light that left the far edge of our own galaxy when our ancestors crossed into Europe is only just arriving now. Immortality doesn't change any of this. You are still a mass. The rocket equation still applies. The physics does not negotiate with biology. Tonight we trace what 100,000 years of continuous consciousness actually does to a human mind — the memory reconsolidation problem that turns your earliest memories into mythology within a few millennia, the hedonic treadmill running out of novelty, the motivational collapse that hyperbolic discounting produces when there is no deadline. We look at what immortality does to the civilization that produces it: the permanent gerontocracy where the founding generation never dies and never makes room, the end of paradigm shifts because the scholars who established the prevailing framework are still alive and still peer-reviewing, the specific reason science advances one funeral at a time — and what happens when the funerals stop. We trace the physical constraints that biology cannot solve: the Tsiolkovsky rocket equation, the radiation environment at relativistic speeds, the communication blackout that is total within centuries of departure. And we ask who steps off the ship after one million years of travel — a being biologically continuous with the person who boarded, and psychologically continuous https://www.youtube-nocookie.com/embed/qF42pnGei6g 7031 2026-05-24T01:23:25.000Z 2026-10-22T19:54:19.416Z https://longevityharbor.com/de/watch/qF42pnGei6g Imagine We Cured Death. Here's Why Immortal Humans Still Couldn't Cross the Galaxy https://i.ytimg.com/vi/qF42pnGei6g/hqdefault.jpg Imagine we cured death. Not slowed it — cured it. The telomeres are stable. The mitochondria repair themselves. The immune system holds indefinitely. Every clinical trial confirms it. You will not age. Not today, not in ten thousand years. Now someone runs the numbers on what that means for crossing the galaxy. The Milky Way is 100,000 light-years in diameter. At the speed of light — which nothing with mass can reach — crossing it takes 100,000 years. At ten percent of light speed, the most optimistic estimate for any propulsion system that uses physics we actually understand, it takes one million years. One million years is three times the total age of Homo sapiens. The light that left the far edge of our own galaxy when our ancestors crossed into Europe is only just arriving now. Immortality doesn't change any of this. You are still a mass. The rocket equation still applies. The physics does not negotiate with biology. Tonight we trace what 100,000 years of continuous consciousness actually does to a human mind — the memory reconsolidation problem that turns your earliest memories into mythology within a few millennia, the hedonic treadmill running out of novelty, the motivational collapse that hyperbolic discounting produces when there is no deadline. We look at what immortality does to the civilization that produces it: the permanent gerontocracy where the founding generation never dies and never makes room, the end of paradigm shifts because the scholars who established the prevailing framework are still alive and still peer-reviewing, the specific reason science advances one funeral at a time — and what happens when the funerals stop. We trace the physical constraints that biology cannot solve: the Tsiolkovsky rocket equation, the radiation environment at relativistic speeds, the communication blackout that is total within centuries of departure. And we ask who steps off the ship after one million years of travel — a being biologically continuous with the person who boarded, and psychologically continuous https://www.youtube-nocookie.com/embed/qF42pnGei6g 7031 2026-05-24T01:23:25.000Z 2026-10-22T19:54:19.416Z https://longevityharbor.com/en/watch/qHNHA3o_Mso Senoskin - So Funktioniert Anti-Aging mit Senolytics und Senomorphics https://i.ytimg.com/vi/qHNHA3o_Mso/hqdefault.jpg In diesem Info-Video werden die Effekte von Seneszenz auf das Altern der haut beschreiben und die Wirkungsweise der neuartigen Anti-Aging Wirkstoffe "Senolytics" und "Senomorphics" erklärt. Diese Wirkstoffe sind in der Hautcreme Formulierung von Senoskin verarbeitet und wirken hier kombiniert mit weiteren Anti-Aging Wirkstoffen. Weitere Infos zu wissenschaftlichen Hintergründen finden sich auf unserer Website: www.senoskin.com https://www.youtube-nocookie.com/embed/qHNHA3o_Mso 94 2025-07-07T14:24:59.000Z 2026-10-23T02:24:27.218Z https://longevityharbor.com/de/watch/qHNHA3o_Mso Senoskin - So Funktioniert Anti-Aging mit Senolytics und Senomorphics https://i.ytimg.com/vi/qHNHA3o_Mso/hqdefault.jpg In diesem Info-Video werden die Effekte von Seneszenz auf das Altern der haut beschreiben und die Wirkungsweise der neuartigen Anti-Aging Wirkstoffe "Senolytics" und "Senomorphics" erklärt. Diese Wirkstoffe sind in der Hautcreme Formulierung von Senoskin verarbeitet und wirken hier kombiniert mit weiteren Anti-Aging Wirkstoffen. Weitere Infos zu wissenschaftlichen Hintergründen finden sich auf unserer Website: www.senoskin.com https://www.youtube-nocookie.com/embed/qHNHA3o_Mso 94 2025-07-07T14:24:59.000Z 2026-10-23T02:24:27.218Z https://longevityharbor.com/en/watch/qJ3uV7coZbA AMA #12: Thoughts on Longevity Supplements (Resveratrol, NR, NMN, Etc.) & How to Improve Memory https://i.ytimg.com/vi/qJ3uV7coZbA/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event Welcome to a preview of the 12th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation. If you're an existing Premium member, you can log in to access the full episode at https://hubermanlab.supercast.com. If you're not a member, you can join Huberman Lab Premium at https://www.hubermanlab.com/premium to enjoy exclusive content, including monthly Ask Me Anything (AMA) episodes, AMA transcripts, podcast episode transcripts, early access to live events and help advance human scientific research. Timestamps 00:00:00 Introduction 00:01:46 Resveratrol and Longevity Supplements 00:26:49 Huberman Lab Premium In the full AMA episode, we discuss: - What Is Working Memory and How to Improve It Social & Website Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter #HubermanLab #Science #AMA Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com The Huberman Lab podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor https://www.youtube-nocookie.com/embed/qJ3uV7coZbA 1748 2023-10-31T18:00:33.000Z 2026-10-22T18:43:09.849Z https://longevityharbor.com/de/watch/qJ3uV7coZbA AMA #12: Thoughts on Longevity Supplements (Resveratrol, NR, NMN, Etc.) & How to Improve Memory https://i.ytimg.com/vi/qJ3uV7coZbA/hqdefault.jpg See Andrew Huberman live in New York, Los Angeles & San Francisco: https://go.hubermanlab.com/protocols-event Welcome to a preview of the 12th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation. If you're an existing Premium member, you can log in to access the full episode at https://hubermanlab.supercast.com. If you're not a member, you can join Huberman Lab Premium at https://www.hubermanlab.com/premium to enjoy exclusive content, including monthly Ask Me Anything (AMA) episodes, AMA transcripts, podcast episode transcripts, early access to live events and help advance human scientific research. Timestamps 00:00:00 Introduction 00:01:46 Resveratrol and Longevity Supplements 00:26:49 Huberman Lab Premium In the full AMA episode, we discuss: - What Is Working Memory and How to Improve It Social & Website Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter #HubermanLab #Science #AMA Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com The Huberman Lab podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor https://www.youtube-nocookie.com/embed/qJ3uV7coZbA 1748 2023-10-31T18:00:33.000Z 2026-10-22T18:43:09.849Z https://longevityharbor.com/en/watch/qK5YWeqMeKc The Next Frontier in Oral Care – Aging, Microbiomes & Circadian Rhythms https://i.ytimg.com/vi/qK5YWeqMeKc/hqdefault.jpg What happens when top minds in oral biology come together for a deep dive into learning, gum health, and the microbiome? In this episode of Dental Formulator’s Playbook, Dr. Robert L. Karlinsey and co-host Tami recap key insights from the 82nd Annual American Institute of Oral Biology Meeting in Palm Springs. From gum recession and age-related microbiome shifts to the future of targeted probiotics, this discussion offers a high-level synthesis of emerging science—with practical takeaways for formulators, brands, and clinicians. Whether you're developing oral-care products, exploring new marketing strategies, or simply curious about what's next in dental science, this is a must-listen. 🔥 Highlights ↠ 🧪 Learning & Product Strategy Research shows that spaced repetition and quality sleep enhance memory and long-term learning. Short, focused R&D sprints (versus prolonged marathons) may yield deeper formulation insights and faster innovation. 🦷 Gum Recession: Surprising Findings Upper gum tissue (maxilla) is easier to repair than lower gum tissue (mandible). Gum recession can, in some cases, reverse naturally—no grafting required. Adults in orthodontic treatment (braces) have an increased risk for gum recession, while teens with orthodontia don’t have an increased risk. Men experience higher rates of gum recession than women—a promising opportunity for male-targeted gum-health products. 🧬 Circadian Clocks & the Oral Microbiome The human clock and the microbiome clock must stay synchronized for optimal health. Oral probiotics may work best before bedtime, when saliva flow slows. Timing matters: aligning delivery with circadian rhythms can amplify efficacy. 🧓 Another Variable – Aging Microbiomes By age 65+, both men and women undergo significant microbiome shifts that influence oral and systemic health. This represents a functional “third phase” of biology, creating formulation needs rarely addressed in current oral-care markets. Probiotics tailored for older adults could mark the next major innovation frontier. https://www.youtube-nocookie.com/embed/qK5YWeqMeKc 1499 2025-11-03T08:01:00.000Z 2026-10-22T19:21:25.227Z https://longevityharbor.com/de/watch/qK5YWeqMeKc The Next Frontier in Oral Care – Aging, Microbiomes & Circadian Rhythms https://i.ytimg.com/vi/qK5YWeqMeKc/hqdefault.jpg What happens when top minds in oral biology come together for a deep dive into learning, gum health, and the microbiome? In this episode of Dental Formulator’s Playbook, Dr. Robert L. Karlinsey and co-host Tami recap key insights from the 82nd Annual American Institute of Oral Biology Meeting in Palm Springs. From gum recession and age-related microbiome shifts to the future of targeted probiotics, this discussion offers a high-level synthesis of emerging science—with practical takeaways for formulators, brands, and clinicians. Whether you're developing oral-care products, exploring new marketing strategies, or simply curious about what's next in dental science, this is a must-listen. 🔥 Highlights ↠ 🧪 Learning & Product Strategy Research shows that spaced repetition and quality sleep enhance memory and long-term learning. Short, focused R&D sprints (versus prolonged marathons) may yield deeper formulation insights and faster innovation. 🦷 Gum Recession: Surprising Findings Upper gum tissue (maxilla) is easier to repair than lower gum tissue (mandible). Gum recession can, in some cases, reverse naturally—no grafting required. Adults in orthodontic treatment (braces) have an increased risk for gum recession, while teens with orthodontia don’t have an increased risk. Men experience higher rates of gum recession than women—a promising opportunity for male-targeted gum-health products. 🧬 Circadian Clocks & the Oral Microbiome The human clock and the microbiome clock must stay synchronized for optimal health. Oral probiotics may work best before bedtime, when saliva flow slows. Timing matters: aligning delivery with circadian rhythms can amplify efficacy. 🧓 Another Variable – Aging Microbiomes By age 65+, both men and women undergo significant microbiome shifts that influence oral and systemic health. This represents a functional “third phase” of biology, creating formulation needs rarely addressed in current oral-care markets. Probiotics tailored for older adults could mark the next major innovation frontier. https://www.youtube-nocookie.com/embed/qK5YWeqMeKc 1499 2025-11-03T08:01:00.000Z 2026-10-22T19:21:25.227Z https://longevityharbor.com/en/watch/qLSvWZqJOjg Does Plant Protein Slow Your Aging? https://i.ytimg.com/vi/qLSvWZqJOjg/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Check out the paper: https://link.springer.com/content/pdf/10.1007/s00394-024-03494-9.pdf We recently came across a study published in the European Journal of Nutrition that examined the relationship between plant and animal protein intake and measures of biological aging. The study, which uses data from the UK Biobank, a long-term database of biological data from half a million participants in the United Kingdom, found that a higher plant protein intake correlates inversely with biological aging. Matt takes us through the study and gives us his take on the results and potential explanations for them as well as on the validity of the biological age measures used, the complexities of nutrition research, and core principles of healthy eating. 2:34 The UK Biobank 4:01 What the researchers did 5:04 Examining a paragraph from the paper 13:17 Key findings 15:18 Likely explanations for the findings 17:53 Final reflections Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twit https://www.youtube-nocookie.com/embed/qLSvWZqJOjg 1227 2024-10-03T13:00:59.000Z 2026-10-22T19:32:34.409Z https://longevityharbor.com/de/watch/qLSvWZqJOjg Does Plant Protein Slow Your Aging? https://i.ytimg.com/vi/qLSvWZqJOjg/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan Check out the paper: https://link.springer.com/content/pdf/10.1007/s00394-024-03494-9.pdf We recently came across a study published in the European Journal of Nutrition that examined the relationship between plant and animal protein intake and measures of biological aging. The study, which uses data from the UK Biobank, a long-term database of biological data from half a million participants in the United Kingdom, found that a higher plant protein intake correlates inversely with biological aging. Matt takes us through the study and gives us his take on the results and potential explanations for them as well as on the validity of the biological age measures used, the complexities of nutrition research, and core principles of healthy eating. 2:34 The UK Biobank 4:01 What the researchers did 5:04 Examining a paragraph from the paper 13:17 Key findings 15:18 Likely explanations for the findings 17:53 Final reflections Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twit https://www.youtube-nocookie.com/embed/qLSvWZqJOjg 1227 2024-10-03T13:00:59.000Z 2026-10-22T19:32:34.409Z https://longevityharbor.com/en/watch/qMMKD5N2txA Video description: collagen-supporting nutrients and foods for healthy aging https://i.ytimg.com/vi/qMMKD5N2txA/hqdefault.jpg The video description says Dr. William Li discusses nutrients and everyday foods that may help the body maintain collagen, support skin elasticity and joint health, and protect existing collagen as we age. It stresses that no food or supplement can stop or reverse aging. https://www.youtube-nocookie.com/embed/qMMKD5N2txA 2295 2026-10-14T14:00:09.000Z 2026-10-22T19:54:40.829Z https://longevityharbor.com/de/watch/qMMKD5N2txA Videobeschreibung: Kollagen-unterstützende Nährstoffe und Lebensmittel für gesundes Altern https://i.ytimg.com/vi/qMMKD5N2txA/hqdefault.jpg Laut Videobeschreibung erläutert Dr. William Li Nährstoffe und Alltagslebensmittel, die dem Körper helfen könnten, Kollagen zu erhalten, die Hautelastizität und Gelenkgesundheit zu unterstützen und vorhandenes Kollagen im Alter zu schützen. Betont wird: Kein Lebensmittel und kein Supplement kann das Altern stoppen oder umkehren. https://www.youtube-nocookie.com/embed/qMMKD5N2txA 2295 2026-10-14T14:00:09.000Z 2026-10-22T19:54:40.829Z https://longevityharbor.com/en/watch/qMVpy0rA-Gc Official Launch of the Geroscience Clinical Trials Units https://i.ytimg.com/vi/qMVpy0rA-Gc/hqdefault.jpg Official Launch of the Geroscience Clinical Trials Units https://www.youtube-nocookie.com/embed/qMVpy0rA-Gc 3456 2026-04-08T21:24:16.000Z 2026-10-22T18:32:11.656Z https://longevityharbor.com/de/watch/qMVpy0rA-Gc Official Launch of the Geroscience Clinical Trials Units https://i.ytimg.com/vi/qMVpy0rA-Gc/hqdefault.jpg Official Launch of the Geroscience Clinical Trials Units https://www.youtube-nocookie.com/embed/qMVpy0rA-Gc 3456 2026-04-08T21:24:16.000Z 2026-10-22T18:32:11.656Z https://longevityharbor.com/en/watch/qNbkQ7TYnU4 Video description: five exercises for strength, balance and mobility with age https://i.ytimg.com/vi/qNbkQ7TYnU4/hqdefault.jpg The description presents five exercises—squats, push-ups, rows, lunges, and walking/cardio—as ways to support strength, balance, mobility, endurance and everyday function with age, and stresses consistency over extreme workouts. https://www.youtube-nocookie.com/embed/qNbkQ7TYnU4 756 2026-09-30T16:44:36.000Z 2026-10-22T21:36:22.075Z https://longevityharbor.com/de/watch/qNbkQ7TYnU4 Videobeschreibung: fünf Übungen für Kraft, Balance und Mobilität im Alter https://i.ytimg.com/vi/qNbkQ7TYnU4/hqdefault.jpg Die Beschreibung stellt fünf Übungen vor – Kniebeugen, Liegestütze, Rudern, Ausfallschritte sowie Gehen/Cardio – als Möglichkeiten, Kraft, Balance, Mobilität, Ausdauer und Alltagsfunktion im Alter zu unterstützen, und betont Beständigkeit statt extremer Workouts. https://www.youtube-nocookie.com/embed/qNbkQ7TYnU4 756 2026-09-30T16:44:36.000Z 2026-10-22T21:36:22.075Z https://longevityharbor.com/en/watch/qR9n5WK9cVg Podcast description: circadian rhythms, meal timing and metabolic health https://i.ytimg.com/vi/qR9n5WK9cVg/hqdefault.jpg In this episode description, nutrition researcher Dr Amy Hutchison discusses metabolic health, the body's 24-hour circadian rhythm and whether meal timing matters; the host also describes her own 10-day continuous glucose monitor observation. https://www.youtube-nocookie.com/embed/qR9n5WK9cVg 2241 2026-03-15T17:25:47.000Z 2026-10-23T02:05:26.431Z https://longevityharbor.com/de/watch/qR9n5WK9cVg Podcast-Beschreibung: circadiane Rhythmen, Essenszeiten und Stoffwechselgesundheit https://i.ytimg.com/vi/qR9n5WK9cVg/hqdefault.jpg In dieser Episodenbeschreibung spricht die Ernährungsforscherin Dr. Amy Hutchison über Stoffwechselgesundheit, den natürlichen 24-Stunden-Rhythmus des Körpers und die Frage, ob Essenszeiten eine Rolle spielen; außerdem schildert die Gastgeberin ihre eigene Beobachtung mit einem kontinuierlichen Glukosemessgerät über 10 Tage. https://www.youtube-nocookie.com/embed/qR9n5WK9cVg 2241 2026-03-15T17:25:47.000Z 2026-10-23T02:05:26.431Z https://longevityharbor.com/en/watch/qRIOaZkS0RI Video description: three foods promoted for seniors, without named evidence https://i.ytimg.com/vi/qRIOaZkS0RI/hqdefault.jpg The description says Dr. William Li explains three foods seniors should eat regularly to support strength, energy and health; the foods themselves are not named, and no study or data is reported. https://www.youtube-nocookie.com/embed/qRIOaZkS0RI 743 2026-05-16T05:00:46.000Z 2026-10-23T00:45:22.825Z https://longevityharbor.com/de/watch/qRIOaZkS0RI Videobeschreibung: drei Lebensmittel für Senioren, ohne benannte Belege https://i.ytimg.com/vi/qRIOaZkS0RI/hqdefault.jpg Laut Beschreibung erklärt Dr. William Li drei Lebensmittel, die Senioren regelmäßig essen sollten, um Kraft, Energie und Gesundheit besser zu unterstützen; die Lebensmittel werden nicht genannt, und es werden keine Studie oder Daten berichtet. https://www.youtube-nocookie.com/embed/qRIOaZkS0RI 743 2026-05-16T05:00:46.000Z 2026-10-23T00:45:22.825Z https://longevityharbor.com/en/watch/qRl4M888jP8 NAD vs NMN which anti aging supplement will be most beneficial as an oral supplement? #nmn https://i.ytimg.com/vi/qRl4M888jP8/hqdefault.jpg NAD vs NMN which anti aging supplement will be most beneficial as an oral supplement? #nmn #newyearnewme #antiaging #tiktokshopjumpstartsale #nad https://www.youtube-nocookie.com/embed/qRl4M888jP8 111 2026-09-30T19:12:02.000Z 2026-10-22T17:43:42.520Z https://longevityharbor.com/de/watch/qRl4M888jP8 NAD vs NMN which anti aging supplement will be most beneficial as an oral supplement? #nmn https://i.ytimg.com/vi/qRl4M888jP8/hqdefault.jpg NAD vs NMN which anti aging supplement will be most beneficial as an oral supplement? #nmn #newyearnewme #antiaging #tiktokshopjumpstartsale #nad https://www.youtube-nocookie.com/embed/qRl4M888jP8 111 2026-09-30T19:12:02.000Z 2026-10-22T17:43:42.520Z https://longevityharbor.com/en/watch/qSt8aKtpDCA The Science of Healthy Aging: Six Keys to a Long, Healthy Life https://i.ytimg.com/vi/qSt8aKtpDCA/hqdefault.jpg Although growing older comes with a number of major life changes, science can help inform the things we do in the here in and now to forestall the most serious features of the aging self, promoting healthspan and not just lifespan. Build Muscle Muscle mass is one the best predictors of health and longevity. Muscle tissue is known to release its own chemicals called myokines, which can have benefits that span cognition, immunity and anti-cancer activity. By performing regular, resistance-based exercise that prioritizes strength, we can delay the loss of bone density and risk of physical injuries. Vitamin D Commonly known as the sunshine vitamin, vitamin D is in fact a critical hormone that helps maintain healthy bones, boost our immune system and improve our cardiovascular function. With age, the production of vitamin D in the skin can become less efficient, so if we don’t spend enough time outdoors, our risk of vitamin D deficiency may increase. Neurodegenerative Diseases One of the most unsettling aspects of aging is the potential for neurodegenerative disease. These conditions are increasingly prevalent in those with diabetes, suggesting that the brain’s blood flow and energy supply may be compromised. Research indicates that regular physical exercise, a healthy whole foods diet and staying intellectually active could at least slow the rate of decline. Mindfulness As we get older, major arteries can become thicker and less flexible, leading to increased blood pressure and undue strain on the heart. A regular mindfulness practice such as yoga or meditation has been shown to stem the release of stress hormones like cortisol and adrenaline. By freeing us from this “fight-or-flight” state, this habit can improve blood flow and reduce the risk of heart attack and stroke. Stay Social As social animals, maintaining a strong sense of community and close personal relationships into old age are underestimated contributors to longevity. While social isolation in seniors can result in significant physical and mental decli https://www.youtube-nocookie.com/embed/qSt8aKtpDCA 168 2021-07-19T13:00:21.000Z 2026-10-22T17:43:36.944Z https://longevityharbor.com/de/watch/qSt8aKtpDCA The Science of Healthy Aging: Six Keys to a Long, Healthy Life https://i.ytimg.com/vi/qSt8aKtpDCA/hqdefault.jpg Although growing older comes with a number of major life changes, science can help inform the things we do in the here in and now to forestall the most serious features of the aging self, promoting healthspan and not just lifespan. Build Muscle Muscle mass is one the best predictors of health and longevity. Muscle tissue is known to release its own chemicals called myokines, which can have benefits that span cognition, immunity and anti-cancer activity. By performing regular, resistance-based exercise that prioritizes strength, we can delay the loss of bone density and risk of physical injuries. Vitamin D Commonly known as the sunshine vitamin, vitamin D is in fact a critical hormone that helps maintain healthy bones, boost our immune system and improve our cardiovascular function. With age, the production of vitamin D in the skin can become less efficient, so if we don’t spend enough time outdoors, our risk of vitamin D deficiency may increase. Neurodegenerative Diseases One of the most unsettling aspects of aging is the potential for neurodegenerative disease. These conditions are increasingly prevalent in those with diabetes, suggesting that the brain’s blood flow and energy supply may be compromised. Research indicates that regular physical exercise, a healthy whole foods diet and staying intellectually active could at least slow the rate of decline. Mindfulness As we get older, major arteries can become thicker and less flexible, leading to increased blood pressure and undue strain on the heart. A regular mindfulness practice such as yoga or meditation has been shown to stem the release of stress hormones like cortisol and adrenaline. By freeing us from this “fight-or-flight” state, this habit can improve blood flow and reduce the risk of heart attack and stroke. Stay Social As social animals, maintaining a strong sense of community and close personal relationships into old age are underestimated contributors to longevity. While social isolation in seniors can result in significant physical and mental decli https://www.youtube-nocookie.com/embed/qSt8aKtpDCA 168 2021-07-19T13:00:21.000Z 2026-10-22T17:43:36.944Z https://longevityharbor.com/en/watch/qVzC7wVsw2c The $101 Million Race to Solve Longevity — XPRIZE Healthspan | Jamie Justice PhD https://i.ytimg.com/vi/qVzC7wVsw2c/hqdefault.jpg What if we could solve longevity — not in mice, but in real humans over 50? Dr. Jamie Justice leads the $101 million XPRIZE Healthspan competition, where 744 teams must prove they can restore muscle, cognition, and immune function by 10–20 years in clinical trials. ⏱️ CHAPTERS: 0:00 - The $101M challenge: restore function in humans over 50 1:00 - Show intro 4:36 - Welcome Dr. Jamie Justice 5:03 - From art and sports therapy to geroscience 8:41 - Tom Johnson vs. Lynn Hayflick debate 11:25 - What drew Jamie to aging research 14:58 - The revolution in longevity science 15:10 - Why aging isn't like an oil tanker wearing out 17:43 - Epigenetic reprogramming and Yamanaka factors 17:54 - Blagosklonny's hyperfunction theory 20:17 - Hallmarks and pillars of aging 23:22 - Geroscience hypothesis explained 25:54 - First senolytic trial — dasatinib + quercetin for IPF 26:46 - Sinclair's epigenetic reprogramming in the eye 27:27 - The ~30% lifespan extension wall in mice 28:48 - Rectangularizing the curve: healthspan = lifespan 30:22 - Negligible senescence in bats and tortoises 32:28 - Partial reprogramming without cancer risk 33:53 - Steve Austad: most interesting man in geroscience 35:01 - The Austad-Olshansky bet on living to 150 37:38 - Longevity escape velocity 39:11 - Maximizing healthspan first 40:29 - XPRIZE Healthspan: $101M competition explained 42:14 - 744 teams — from high schoolers to Harvard 43:38 - Rapamycin, GLP-1 agonists, gene therapy landscape 46:07 - Finals: results-based, multi-system improvements 49:11 - Wildest and most unexpected entries 50:51 - Circadian rhythm team with dramatic results 52:43 - The heterochronic parabiosis dating app 54:07 - Timeline: finalists announced August 2026 55:51 - Winning nodes: metabolism and immune-targeting 57:03 - Reprogramming, mitochondria, and senolytics 58:32 - XPRIZE ovarian health prize 1:01:26 - Closing 📚 REFERENCES: Hallmarks of Aging (López-Otín et al., Cell 2013): https://doi.org/10.1016/j.cell.2013.05.039 XPRIZE Healthspan: https://www.xprize.org/prizes/h https://www.youtube-nocookie.com/embed/qVzC7wVsw2c 3885 2026-03-20T15:13:51.000Z 2026-10-22T19:04:38.619Z https://longevityharbor.com/de/watch/qVzC7wVsw2c The $101 Million Race to Solve Longevity — XPRIZE Healthspan | Jamie Justice PhD https://i.ytimg.com/vi/qVzC7wVsw2c/hqdefault.jpg What if we could solve longevity — not in mice, but in real humans over 50? Dr. Jamie Justice leads the $101 million XPRIZE Healthspan competition, where 744 teams must prove they can restore muscle, cognition, and immune function by 10–20 years in clinical trials. ⏱️ CHAPTERS: 0:00 - The $101M challenge: restore function in humans over 50 1:00 - Show intro 4:36 - Welcome Dr. Jamie Justice 5:03 - From art and sports therapy to geroscience 8:41 - Tom Johnson vs. Lynn Hayflick debate 11:25 - What drew Jamie to aging research 14:58 - The revolution in longevity science 15:10 - Why aging isn't like an oil tanker wearing out 17:43 - Epigenetic reprogramming and Yamanaka factors 17:54 - Blagosklonny's hyperfunction theory 20:17 - Hallmarks and pillars of aging 23:22 - Geroscience hypothesis explained 25:54 - First senolytic trial — dasatinib + quercetin for IPF 26:46 - Sinclair's epigenetic reprogramming in the eye 27:27 - The ~30% lifespan extension wall in mice 28:48 - Rectangularizing the curve: healthspan = lifespan 30:22 - Negligible senescence in bats and tortoises 32:28 - Partial reprogramming without cancer risk 33:53 - Steve Austad: most interesting man in geroscience 35:01 - The Austad-Olshansky bet on living to 150 37:38 - Longevity escape velocity 39:11 - Maximizing healthspan first 40:29 - XPRIZE Healthspan: $101M competition explained 42:14 - 744 teams — from high schoolers to Harvard 43:38 - Rapamycin, GLP-1 agonists, gene therapy landscape 46:07 - Finals: results-based, multi-system improvements 49:11 - Wildest and most unexpected entries 50:51 - Circadian rhythm team with dramatic results 52:43 - The heterochronic parabiosis dating app 54:07 - Timeline: finalists announced August 2026 55:51 - Winning nodes: metabolism and immune-targeting 57:03 - Reprogramming, mitochondria, and senolytics 58:32 - XPRIZE ovarian health prize 1:01:26 - Closing 📚 REFERENCES: Hallmarks of Aging (López-Otín et al., Cell 2013): https://doi.org/10.1016/j.cell.2013.05.039 XPRIZE Healthspan: https://www.xprize.org/prizes/h https://www.youtube-nocookie.com/embed/qVzC7wVsw2c 3885 2026-03-20T15:13:51.000Z 2026-10-22T19:04:38.619Z https://longevityharbor.com/en/watch/qWjy85z6zv8 Podcast description: longevity science, healthspan and prevention https://i.ytimg.com/vi/qWjy85z6zv8/hqdefault.jpg The description presents a podcast episode in which Barry Skillington talks with Martin O'Dea about longevity science, healthy aging, healthspan and disease prevention. It lists topics such as rapamycin, metformin, cellular reprogramming, biomarkers and lifestyle; no results are reported. https://www.youtube-nocookie.com/embed/qWjy85z6zv8 3406 2026-06-23T04:30:19.000Z 2026-10-22T23:49:04.662Z https://longevityharbor.com/de/watch/qWjy85z6zv8 Podcast-Beschreibung: Longevity-Wissenschaft, Healthspan und Prävention https://i.ytimg.com/vi/qWjy85z6zv8/hqdefault.jpg Die Beschreibung stellt eine Podcast-Folge vor, in der Barry Skillington mit Martin O'Dea über Longevity-Wissenschaft, gesundes Altern, Healthspan und Krankheitsprävention spricht. Sie nennt Themen wie Rapamycin, Metformin, zelluläre Reprogrammierung, Biomarker und Lebensstil; Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/qWjy85z6zv8 3406 2026-06-23T04:30:19.000Z 2026-10-22T23:49:04.662Z https://longevityharbor.com/en/watch/qakucyhZW_w Video description on senescent cells, SASP and senolytic supplements https://i.ytimg.com/vi/qakucyhZW_w/hqdefault.jpg The description says a 90-second clinical breakdown by Dr. Ferehan Siraj Nuru MD covers cellular senescence, SASP inflammation and ways to clear cellular debris; it names no results. https://www.youtube-nocookie.com/embed/qakucyhZW_w 98 2026-08-18T21:00:34.000Z 2026-10-22T22:56:17.717Z https://longevityharbor.com/de/watch/qakucyhZW_w Videobeschreibung zu seneszenten Zellen, SASP und senolytischen Präparaten https://i.ytimg.com/vi/qakucyhZW_w/hqdefault.jpg Laut Beschreibung behandelt ein 90-sekündiger klinischer Überblick von Dr. Ferehan Siraj Nuru MD zelluläre Seneszenz, SASP-Entzündung und Wege zum Abbau zellulärer Ablagerungen; Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/qakucyhZW_w 98 2026-08-18T21:00:34.000Z 2026-10-22T22:56:17.717Z https://longevityharbor.com/en/watch/qay0nUwChzw Rapamycin, human longevity and the PEARL study https://i.ytimg.com/vi/qay0nUwChzw/hqdefault.jpg A brief overview of the PEARL study- the longest and largest RCT looking at Rapamycin as a possible treatment for human aging. Watch this space! #longevity #healthspan #rapamycin #antiaging https://www.youtube-nocookie.com/embed/qay0nUwChzw 283 2024-09-18T20:34:50.000Z 2026-10-22T18:43:08.040Z https://longevityharbor.com/de/watch/qay0nUwChzw Rapamycin, human longevity and the PEARL study https://i.ytimg.com/vi/qay0nUwChzw/hqdefault.jpg A brief overview of the PEARL study- the longest and largest RCT looking at Rapamycin as a possible treatment for human aging. Watch this space! #longevity #healthspan #rapamycin #antiaging https://www.youtube-nocookie.com/embed/qay0nUwChzw 283 2024-09-18T20:34:50.000Z 2026-10-22T18:43:08.040Z https://longevityharbor.com/en/watch/qb0BSEH-ijk Fasting Mimicking Diet Cycles, Longevity, & Age-Related Diseases https://i.ytimg.com/vi/qb0BSEH-ijk/hqdefault.jpg Thank you for joining us for "Fasting Mimicking Diet Cycles, Longevity, & Age-Related Diseases," a lecture by Valter Longo, PhD, renowned expert in aging and disease, director of the USC Longevity Institute, and developer of the fasting mimicking diet. Dr. Longo gave the talk as part of the George Washington University School of Medicine & Health Sciences' 8th Annual Patrick & Marguerite Sung Symposium: Intermittent Fasting for Well-being on March 28, 2025. Organized by the GW Office of Integrative Medicine and Health (OIMH), this free online symposium explored the scientific foundations and practical applications of fasting as a tool for enhancing overall health. Dr. Longo is the author of "Fasting Cancer: How Fasting and Nutritechnology Are Creating a Revolution in Cancer Prevention and Treatment." Learn more about Integrative Medicine and the OIMH! https://oimh.smhs.gwu.edu/ https://www.youtube-nocookie.com/embed/qb0BSEH-ijk 2635 2025-04-01T03:20:25.000Z 2026-10-22T18:54:08.135Z https://longevityharbor.com/de/watch/qb0BSEH-ijk Fasting Mimicking Diet Cycles, Longevity, & Age-Related Diseases https://i.ytimg.com/vi/qb0BSEH-ijk/hqdefault.jpg Thank you for joining us for "Fasting Mimicking Diet Cycles, Longevity, & Age-Related Diseases," a lecture by Valter Longo, PhD, renowned expert in aging and disease, director of the USC Longevity Institute, and developer of the fasting mimicking diet. Dr. Longo gave the talk as part of the George Washington University School of Medicine & Health Sciences' 8th Annual Patrick & Marguerite Sung Symposium: Intermittent Fasting for Well-being on March 28, 2025. Organized by the GW Office of Integrative Medicine and Health (OIMH), this free online symposium explored the scientific foundations and practical applications of fasting as a tool for enhancing overall health. Dr. Longo is the author of "Fasting Cancer: How Fasting and Nutritechnology Are Creating a Revolution in Cancer Prevention and Treatment." Learn more about Integrative Medicine and the OIMH! https://oimh.smhs.gwu.edu/ https://www.youtube-nocookie.com/embed/qb0BSEH-ijk 2635 2025-04-01T03:20:25.000Z 2026-10-22T18:54:08.135Z https://longevityharbor.com/en/watch/qdi6myJHe_A Targeting aging with rapamycin: On the path toward 21st Century Medicine https://i.ytimg.com/vi/qdi6myJHe_A/hqdefault.jpg This video is for attendees of the 2022 Aging Research and Drug Discovery (ARDD) conference. It features a lecture given by Matt Kaeberlein in Bregenz, Austria on July 15, 2022. https://www.youtube-nocookie.com/embed/qdi6myJHe_A 2245 2022-08-28T15:05:05.000Z 2026-10-22T17:43:41.784Z https://longevityharbor.com/de/watch/qdi6myJHe_A Targeting aging with rapamycin: On the path toward 21st Century Medicine https://i.ytimg.com/vi/qdi6myJHe_A/hqdefault.jpg This video is for attendees of the 2022 Aging Research and Drug Discovery (ARDD) conference. It features a lecture given by Matt Kaeberlein in Bregenz, Austria on July 15, 2022. https://www.youtube-nocookie.com/embed/qdi6myJHe_A 2245 2022-08-28T15:05:05.000Z 2026-10-22T17:43:41.784Z https://longevityharbor.com/en/watch/qe6dSDq5GV0 How Fasting & Caloric Restriction Impact Health | Dr. Satchin Panda & Dr. Andrew Huberman https://i.ytimg.com/vi/qe6dSDq5GV0/hqdefault.jpg Dr. Satchin Panda and Dr. Andrew Huberman discuss the relationship between caloric restriction and time-restricted feeding, revealing surprising insights into longevity and challenging popular interpretations of intermittent fasting. Satchin Panda, PhD, is a professor and the director of the Regulatory Biology Laboratories at the Salk Institute for Biological Studies. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast. Watch the full episode: https://youtu.be/7R3-3HR6-u4 Show notes: https://www.hubermanlab.com/episode/dr-satchin-panda-intermittent-fasting-to-improve-health-cognition-and-longevity Social & Website Instagram: https://www.instagram.com/hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter #HubermanLab #Fasting #IntermittentFasting The Huberman Lab podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. https://www.youtube-nocookie.com/embed/qe6dSDq5GV0 791 2023-11-01T01:36:34.000Z 2026-10-22T17:43:38.402Z https://longevityharbor.com/de/watch/qe6dSDq5GV0 How Fasting & Caloric Restriction Impact Health | Dr. Satchin Panda & Dr. Andrew Huberman https://i.ytimg.com/vi/qe6dSDq5GV0/hqdefault.jpg Dr. Satchin Panda and Dr. Andrew Huberman discuss the relationship between caloric restriction and time-restricted feeding, revealing surprising insights into longevity and challenging popular interpretations of intermittent fasting. Satchin Panda, PhD, is a professor and the director of the Regulatory Biology Laboratories at the Salk Institute for Biological Studies. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast. Watch the full episode: https://youtu.be/7R3-3HR6-u4 Show notes: https://www.hubermanlab.com/episode/dr-satchin-panda-intermittent-fasting-to-improve-health-cognition-and-longevity Social & Website Instagram: https://www.instagram.com/hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter #HubermanLab #Fasting #IntermittentFasting The Huberman Lab podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. https://www.youtube-nocookie.com/embed/qe6dSDq5GV0 791 2023-11-01T01:36:34.000Z 2026-10-22T17:43:38.402Z https://longevityharbor.com/en/watch/qf8nUkZwgYg Dogs reveal new blood biomarkers of aging: insights from the dog aging project https://i.ytimg.com/vi/qf8nUkZwgYg/hqdefault.jpg This video summarizes the paper “Protein Catabolites as Blood-Based Biomarkers of Aging Physiology: Findings from the Dog Aging Project” by Benjamin R. Harrison et al. (Aging Cell, 2025). Using blood samples from 784 companion dogs across the United States, the researchers performed large-scale plasma metabolomics to uncover how age alters metabolism in real-world genetic and environmental contexts. They found that about 36% of metabolites changed with age, with strong effects in acylcarnitines and post-translationally modified amino acids (ptmAAs), which are molecular by-products of protein breakdown. These ptmAAs increased consistently with age and were tightly linked to clinical markers of kidney function, such as creatinine and blood urea nitrogen, suggesting that slower clearance of protein catabolites contributes to age-related shifts in the blood metabolome. By integrating metabolomics with genomic and clinical data, the Dog Aging Project establishes ptmAAs as robust, diet-independent biomarkers of biological aging in dogs — and potentially in humans. This study highlights how our canine companions can accelerate discoveries in geroscience, bridging laboratory insights and natural aging in complex, diverse populations. https://www.youtube-nocookie.com/embed/qf8nUkZwgYg 345 2025-10-26T07:00:53.000Z 2026-10-22T19:04:38.634Z https://longevityharbor.com/de/watch/qf8nUkZwgYg Dogs reveal new blood biomarkers of aging: insights from the dog aging project https://i.ytimg.com/vi/qf8nUkZwgYg/hqdefault.jpg This video summarizes the paper “Protein Catabolites as Blood-Based Biomarkers of Aging Physiology: Findings from the Dog Aging Project” by Benjamin R. Harrison et al. (Aging Cell, 2025). Using blood samples from 784 companion dogs across the United States, the researchers performed large-scale plasma metabolomics to uncover how age alters metabolism in real-world genetic and environmental contexts. They found that about 36% of metabolites changed with age, with strong effects in acylcarnitines and post-translationally modified amino acids (ptmAAs), which are molecular by-products of protein breakdown. These ptmAAs increased consistently with age and were tightly linked to clinical markers of kidney function, such as creatinine and blood urea nitrogen, suggesting that slower clearance of protein catabolites contributes to age-related shifts in the blood metabolome. By integrating metabolomics with genomic and clinical data, the Dog Aging Project establishes ptmAAs as robust, diet-independent biomarkers of biological aging in dogs — and potentially in humans. This study highlights how our canine companions can accelerate discoveries in geroscience, bridging laboratory insights and natural aging in complex, diverse populations. https://www.youtube-nocookie.com/embed/qf8nUkZwgYg 345 2025-10-26T07:00:53.000Z 2026-10-22T19:04:38.634Z https://longevityharbor.com/en/watch/qhilRCmPgHI Sleep duration, circadian aging and lifespan: claims from a video description https://i.ytimg.com/vi/qhilRCmPgHI/hqdefault.jpg The description links about 7 hours of sleep to the lowest mortality risk, describes circadian and molecular mechanisms of aging, and reports that restoring sleep in young fruit flies extended lifespan but not in older flies. https://www.youtube-nocookie.com/embed/qhilRCmPgHI 2300 2026-02-27T06:44:10.000Z 2026-10-23T02:19:29.278Z https://longevityharbor.com/de/watch/qhilRCmPgHI Schlafdauer, zirkadianes Altern und Lebensspanne: Aussagen einer Videobeschreibung https://i.ytimg.com/vi/qhilRCmPgHI/hqdefault.jpg Die Beschreibung verbindet etwa 7 Stunden Schlaf mit dem niedrigsten Sterberisiko, beschreibt zirkadiane und molekulare Alternsmechanismen und berichtet, dass Schlafwiederherstellung bei jungen Fruchtfliegen die Lebensspanne verlängerte, bei älteren nicht. https://www.youtube-nocookie.com/embed/qhilRCmPgHI 2300 2026-02-27T06:44:10.000Z 2026-10-23T02:19:29.278Z https://longevityharbor.com/en/watch/qiAW3sUoJYA Lecture on rapamycin: from Streptomyces natural product to mTOR inhibitor https://i.ytimg.com/vi/qiAW3sUoJYA/hqdefault.jpg The description says this lecture traces rapamycin from a natural product of Streptomyces found on Rapa Nui to an immunosuppressive and immunomodulatory drug acting through FKBP12-mediated mTOR inhibition, and lists clinical uses, rapalogs, autophagy and aging links as topics. https://www.youtube-nocookie.com/embed/qiAW3sUoJYA 1205 2026-02-08T16:41:02.000Z 2026-10-23T02:36:19.886Z https://longevityharbor.com/de/watch/qiAW3sUoJYA Vortrag über Rapamycin: vom Streptomyces-Naturstoff zum mTOR-Hemmer https://i.ytimg.com/vi/qiAW3sUoJYA/hqdefault.jpg Laut Beschreibung zeichnet der Vortrag Rapamycins Weg vom Naturstoff aus Streptomyces von Rapa Nui zum immunsuppressiven und immunmodulierenden Arzneimittel nach, das über FKBP12-vermitteltes mTOR-Hemmen wirkt, und nennt klinische Anwendungen, Rapaloge, Autophagie und Altern als Themen. https://www.youtube-nocookie.com/embed/qiAW3sUoJYA 1205 2026-02-08T16:41:02.000Z 2026-10-23T02:36:19.886Z https://longevityharbor.com/en/watch/qmNsb5--yTw Dr. Alexander G. Haslberger: Epigenetik und Mikrobiota Marker in der personalisierten Ernährung https://i.ytimg.com/vi/qmNsb5--yTw/hqdefault.jpg Dr. Alexander G. Haslberger studierte Mikrobiologie und Genetik. Seine Forschungsgebiete sind Immunantworten, Mikrobiota, Epigenetik, molekulare Ernährung und gesundes Altern. Gesundheitserhaltung und Krankheitsprävention sind zentrale Ziele der Gesundheitspolitik. Molekulare Mechanismen des Alterns, vorzeitiges Altern und die Entwicklung alterskorrelierter, komplexer Erkrankungen werden von wissenschaftlichen Disziplinen Schritt für Schritt analysiert und in die "hallmarks of aging" integriert. Studien mit der "epigenetischen Uhr" zeigten die positiven Auswirkungen von Fasten und Diäten auf ein gesundes Altern. https://www.youtube-nocookie.com/embed/qmNsb5--yTw 1409 2022-01-24T12:20:51.000Z 2026-10-22T17:11:30.670Z https://longevityharbor.com/de/watch/qmNsb5--yTw Dr. Alexander G. Haslberger: Epigenetik und Mikrobiota Marker in der personalisierten Ernährung https://i.ytimg.com/vi/qmNsb5--yTw/hqdefault.jpg Dr. Alexander G. Haslberger studierte Mikrobiologie und Genetik. Seine Forschungsgebiete sind Immunantworten, Mikrobiota, Epigenetik, molekulare Ernährung und gesundes Altern. Gesundheitserhaltung und Krankheitsprävention sind zentrale Ziele der Gesundheitspolitik. Molekulare Mechanismen des Alterns, vorzeitiges Altern und die Entwicklung alterskorrelierter, komplexer Erkrankungen werden von wissenschaftlichen Disziplinen Schritt für Schritt analysiert und in die "hallmarks of aging" integriert. Studien mit der "epigenetischen Uhr" zeigten die positiven Auswirkungen von Fasten und Diäten auf ein gesundes Altern. https://www.youtube-nocookie.com/embed/qmNsb5--yTw 1409 2022-01-24T12:20:51.000Z 2026-10-22T17:11:30.670Z https://longevityharbor.com/en/watch/qnPPqLvFTFQ Video description: resistance training for age-related muscle loss https://i.ytimg.com/vi/qnPPqLvFTFQ/hqdefault.jpg The description says the video covers sarcopenia, age-related muscle loss, and presents resistance training as a key strategy for prevention and healthy aging. It links to a course and to cited research articles. https://www.youtube-nocookie.com/embed/qnPPqLvFTFQ 130 2026-05-19T20:20:13.000Z 2026-10-23T00:38:06.356Z https://longevityharbor.com/de/watch/qnPPqLvFTFQ Videobeschreibung: Krafttraining gegen altersassoziierten Muskelabbau https://i.ytimg.com/vi/qnPPqLvFTFQ/hqdefault.jpg Laut Beschreibung behandelt das Video Sarkopenie, altersassoziierten Muskelabbau, und stellt Krafttraining als wichtige Strategie zur Vorbeugung und für gesundes Altern dar. Es verweist auf einen Kurs und auf zitierte Forschungsartikel. https://www.youtube-nocookie.com/embed/qnPPqLvFTFQ 130 2026-05-19T20:20:13.000Z 2026-10-23T00:38:06.356Z https://longevityharbor.com/en/watch/qoameU8jNaw Morgan Levine discusses biological versus chronological age and aging research https://i.ytimg.com/vi/qoameU8jNaw/hqdefault.jpg In this video description, Morgan Levine is presented as exploring how biological age is calculated and how fast the body is aging, alongside topics such as epigenetic measurement, lifestyle, caloric restriction and cell reprogramming. https://www.youtube-nocookie.com/embed/qoameU8jNaw 3278 2026-01-23T14:01:23.000Z 2026-10-23T02:46:58.727Z https://longevityharbor.com/de/watch/qoameU8jNaw Morgan Levine über biologisches versus chronologisches Alter und Alternsforschung https://i.ytimg.com/vi/qoameU8jNaw/hqdefault.jpg In dieser Videobeschreibung wird Morgan Levine so vorgestellt, dass sie untersucht, wie das biologische Alter berechnet wird und wie schnell der Körper altert, neben Themen wie epigenetischer Messung, Lebensstil, Kalorienrestriktion und Zell-Reprogrammierung. https://www.youtube-nocookie.com/embed/qoameU8jNaw 3278 2026-01-23T14:01:23.000Z 2026-10-23T02:46:58.727Z https://longevityharbor.com/en/watch/qpBKvLSQcAE Video description: three protein-rich cheeses proposed for muscle after 60 https://i.ytimg.com/vi/qpBKvLSQcAE/hqdefault.jpg The description presents Swiss cheese, cottage cheese and Parmigiano-Reggiano as protein-rich foods that may support muscle maintenance after 60, and stresses that nutrition, resistance exercise, hydration and time all matter. https://www.youtube-nocookie.com/embed/qpBKvLSQcAE 1235 2026-10-05T21:09:54.000Z 2026-10-22T21:18:50.492Z https://longevityharbor.com/de/watch/qpBKvLSQcAE Videobeschreibung: drei proteinreiche Käsesorten als Vorschlag für Muskeln ab 60 https://i.ytimg.com/vi/qpBKvLSQcAE/hqdefault.jpg Die Beschreibung stellt Schweizer Käse, Hüttenkäse und Parmigiano-Reggiano als proteinreiche Lebensmittel vor, die die Muskelerhaltung ab 60 unterstützen könnten, und betont, dass Ernährung, Krafttraining, Flüssigkeit und Zeit alle wichtig sind. https://www.youtube-nocookie.com/embed/qpBKvLSQcAE 1235 2026-10-05T21:09:54.000Z 2026-10-22T21:18:50.492Z https://longevityharbor.com/en/watch/qqIb0qT4670 Video description: three no-equipment leg exercises for adults over 60 https://i.ytimg.com/vi/qqIb0qT4670/hqdefault.jpg The description presents three no-equipment exercises for adults over 60 — sit-to-stand, heel-to-toe stand and standing march — in a 21-day, three-day-a-week routine of ten to fifteen minutes. It attributes strength, balance and coordination goals to them but reports no measured results. https://www.youtube-nocookie.com/embed/qqIb0qT4670 866 2026-08-06T18:24:21.000Z 2026-10-22T23:13:35.275Z https://longevityharbor.com/de/watch/qqIb0qT4670 Videobeschreibung: drei Geräte-freie Beinübungen für Erwachsene über 60 https://i.ytimg.com/vi/qqIb0qT4670/hqdefault.jpg Die Beschreibung stellt drei Geräte-freie Übungen für Erwachsene über 60 vor – Sit-to-Stand, Ferse-an-Zehe-Stand und Standmarsch – in einem 21-Tage-Programm an drei Tagen pro Woche mit zehn bis fünfzehn Minuten. Sie nennt Kraft-, Gleichgewichts- und Koordinationsziele, berichtet aber keine gemessenen Ergebnisse. https://www.youtube-nocookie.com/embed/qqIb0qT4670 866 2026-08-06T18:24:21.000Z 2026-10-22T23:13:35.275Z https://longevityharbor.com/en/watch/r-WgbfTF6q4 Rapamycin: What’s New for Human Longevity? | Rapamycin Update | RobertLufkinMD https://i.ytimg.com/vi/r-WgbfTF6q4/hqdefault.jpg Rapamycin: What’s New for Human Longevity? | Rapamycin Update | RobertLufkinMD Can rapamycin be the key to unlocking a longer, healthier life? Join us as Krister Kauppi, a dedicated health and longevity enthusiast, shares his captivating journey from a personal health scare to discovering the potential of rapamycin as an alternative to intermittent fasting. We delve into the science behind this intriguing compound, focusing on how it inhibits mTOR and activates catabolic processes, potentially slowing down aging and reducing the incidence of age-related diseases. Together, we explore the delicate balance between anabolic and catabolic processes and the significant roles that insulin, insulin-like growth factor, and testosterone play in these pathways. Krister also opens up about his personal experiences with rapamycin, highlighting the crucial importance of personalized dosages and the remarkable benefits he observed, such as improved dental health and reduced inflammation. We discuss the exciting concept of longevity cocktails—combinations of fasting, rapamycin, and other interventions aimed at extending lifespan. Learn about the innovative work being done at the Rapamycin Longevity Lab and their mission to create advanced longevity solutions, leveraging cutting-edge technology like Ora Biomedical's WormBot. This episode is a compelling invitation to join us on a groundbreaking journey towards enhancing human longevity. https://masteronething.com/ https://www.linkedin.com/in/krister-kauppi/recent-activity/all/ These sponsors support this podcast: Siphox Health, at-home health testing for all (15% off with this link): https://pathlongevity.com/ Prolon, maker of the Fasting Mimicking Diet (20% off with this link): https://prolonlife.com/Lufkin Osteoporosis detection without DEXA radiation ($50 off with code LUFKIN50): https://robertlufkinmd.com Download a free sample chapter of Lies I Taught In Medical School here: https://www.robertlufkinmd.com/lies/ https://www.youtube-nocookie.com/embed/r-WgbfTF6q4 2359 2024-09-06T22:08:10.000Z 2026-10-22T19:54:21.250Z https://longevityharbor.com/de/watch/r-WgbfTF6q4 Rapamycin: What’s New for Human Longevity? | Rapamycin Update | RobertLufkinMD https://i.ytimg.com/vi/r-WgbfTF6q4/hqdefault.jpg Rapamycin: What’s New for Human Longevity? | Rapamycin Update | RobertLufkinMD Can rapamycin be the key to unlocking a longer, healthier life? Join us as Krister Kauppi, a dedicated health and longevity enthusiast, shares his captivating journey from a personal health scare to discovering the potential of rapamycin as an alternative to intermittent fasting. We delve into the science behind this intriguing compound, focusing on how it inhibits mTOR and activates catabolic processes, potentially slowing down aging and reducing the incidence of age-related diseases. Together, we explore the delicate balance between anabolic and catabolic processes and the significant roles that insulin, insulin-like growth factor, and testosterone play in these pathways. Krister also opens up about his personal experiences with rapamycin, highlighting the crucial importance of personalized dosages and the remarkable benefits he observed, such as improved dental health and reduced inflammation. We discuss the exciting concept of longevity cocktails—combinations of fasting, rapamycin, and other interventions aimed at extending lifespan. Learn about the innovative work being done at the Rapamycin Longevity Lab and their mission to create advanced longevity solutions, leveraging cutting-edge technology like Ora Biomedical's WormBot. This episode is a compelling invitation to join us on a groundbreaking journey towards enhancing human longevity. https://masteronething.com/ https://www.linkedin.com/in/krister-kauppi/recent-activity/all/ These sponsors support this podcast: Siphox Health, at-home health testing for all (15% off with this link): https://pathlongevity.com/ Prolon, maker of the Fasting Mimicking Diet (20% off with this link): https://prolonlife.com/Lufkin Osteoporosis detection without DEXA radiation ($50 off with code LUFKIN50): https://robertlufkinmd.com Download a free sample chapter of Lies I Taught In Medical School here: https://www.robertlufkinmd.com/lies/ https://www.youtube-nocookie.com/embed/r-WgbfTF6q4 2359 2024-09-06T22:08:10.000Z 2026-10-22T19:54:21.250Z https://longevityharbor.com/en/watch/r1jH7GPzALQ Sleep-audio video description outlines 12 hallmarks of aging https://i.ytimg.com/vi/r1jH7GPzALQ/hqdefault.jpg The description presents a sleep-oriented science audio that promises to explain the 12 hallmarks of aging, from DNA damage and telomeres to senescence and inflammation, and to discuss evidence-based interventions and what is real versus hype. https://www.youtube-nocookie.com/embed/r1jH7GPzALQ 9305 2026-01-22T20:33:56.000Z 2026-10-23T02:48:10.995Z https://longevityharbor.com/de/watch/r1jH7GPzALQ Schlaf-Audio-Beschreibung skizziert 12 Hallmarks des Alterns https://i.ytimg.com/vi/r1jH7GPzALQ/hqdefault.jpg Die Beschreibung stellt ein schlafbegleitendes Wissenschafts-Audio vor, das die 12 Hallmarks des Alterns erklären soll – von DNA-Schäden und Telomeren bis zu Seneszenz und Entzündung – und belegte Interventionen sowie Realität gegenüber Hype besprechen will. https://www.youtube-nocookie.com/embed/r1jH7GPzALQ 9305 2026-01-22T20:33:56.000Z 2026-10-23T02:48:10.995Z https://longevityharbor.com/en/watch/r3KMxw-_Xk0 NMN & NAD explained fast. Aging science is evolving. More info in description. https://i.ytimg.com/vi/r3KMxw-_Xk0/hqdefault.jpg NMN is trending in longevity research right now. People are exploring how it supports NAD levels, cellular energy, and healthy aging. Still evolving science — always research what fits your body. Details in profile. #HealthyAging #LongevityScience #WellnessSupplements #BiohackingBasics #MidlifeWellness Check it out here👉 https://www.tiktok.com/t/ZP9eRRqaNUqfM-dHCo6/ https://www.youtube-nocookie.com/embed/r3KMxw-_Xk0 104 2026-02-19T03:09:14.000Z 2026-10-22T18:43:09.990Z https://longevityharbor.com/de/watch/r3KMxw-_Xk0 NMN & NAD explained fast. Aging science is evolving. More info in description. https://i.ytimg.com/vi/r3KMxw-_Xk0/hqdefault.jpg NMN is trending in longevity research right now. People are exploring how it supports NAD levels, cellular energy, and healthy aging. Still evolving science — always research what fits your body. Details in profile. #HealthyAging #LongevityScience #WellnessSupplements #BiohackingBasics #MidlifeWellness Check it out here👉 https://www.tiktok.com/t/ZP9eRRqaNUqfM-dHCo6/ https://www.youtube-nocookie.com/embed/r3KMxw-_Xk0 104 2026-02-19T03:09:14.000Z 2026-10-22T18:43:09.990Z https://longevityharbor.com/en/watch/rFJF5JBnNN4 Which Diet Extends Your Life? Comparing Mediterranean, Keto, Fasting & Calorie Restriction https://i.ytimg.com/vi/rFJF5JBnNN4/hqdefault.jpg In this evidence-based guide, Dr. Sean Hashmi reveals the science-backed truth about four popular dietary approaches to longevity and shares practical, actionable strategies to extend your healthspan. Learn why controlling mTOR and insulin levels through your diet choices may be the key to living longer and healthier. ABOUT THIS VIDEO Dr. Hashmi analyzes four distinct dietary approaches to healthy aging: calorie restriction, intermittent fasting, Mediterranean diet, and ketogenic diet. Each approach affects cellular pathways differently, but all show promise for extending healthspan through mechanisms involving mTOR reduction, improved insulin sensitivity, and reduced inflammation. Discover which approach might be best for your lifestyle and goals. QUICK NAVIGATION 00:00 - Introduction 00:30 - Lifespan vs. Healthspan Explained 01:05 - Key Molecular Mechanisms of Aging (mTOR) 03:15 - Calorie Restriction: The Most Proven Approach 06:10 - Intermittent Fasting: Benefits Beyond Weight Loss 09:05 - Mediterranean Diet: Plant-Based Longevity 12:05 - Ketogenic Diet: Metabolic Adaptation 14:50 - Common Mechanisms Across All Approaches 17:00 - Practical Implementation Strategies 20:30 - Q&A Session KEY INSIGHTS Calorie restriction of 25% showed significant reduction in biological aging markers in human studies All four dietary approaches (calorie restriction, fasting, Mediterranean, ketogenic) reduce mTOR activity, which is central to aging processes Reducing insulin levels is a key mechanism for extending healthspan across all effective longevity diets The Mediterranean diet offers longevity benefits without calorie restriction through anti-inflammatory effects and improved gut bacteria SCIENTIFIC REFERENCES The CALERIE Trial (2019-2023): Showed significant reduction in biological aging markers with 25% calorie restriction Alternate-Day Fasting Trial (2020-2023): Demonstrated reduced inflammatory markers and pro-aging amino acids ABOUT DR. SEAN HASHMI Dr. Sean Hashmi is a board-certified physician specializing in Ne https://www.youtube-nocookie.com/embed/rFJF5JBnNN4 2109 2024-09-12T12:42:16.000Z 2026-10-22T19:54:18.389Z https://longevityharbor.com/de/watch/rFJF5JBnNN4 Which Diet Extends Your Life? Comparing Mediterranean, Keto, Fasting & Calorie Restriction https://i.ytimg.com/vi/rFJF5JBnNN4/hqdefault.jpg In this evidence-based guide, Dr. Sean Hashmi reveals the science-backed truth about four popular dietary approaches to longevity and shares practical, actionable strategies to extend your healthspan. Learn why controlling mTOR and insulin levels through your diet choices may be the key to living longer and healthier. ABOUT THIS VIDEO Dr. Hashmi analyzes four distinct dietary approaches to healthy aging: calorie restriction, intermittent fasting, Mediterranean diet, and ketogenic diet. Each approach affects cellular pathways differently, but all show promise for extending healthspan through mechanisms involving mTOR reduction, improved insulin sensitivity, and reduced inflammation. Discover which approach might be best for your lifestyle and goals. QUICK NAVIGATION 00:00 - Introduction 00:30 - Lifespan vs. Healthspan Explained 01:05 - Key Molecular Mechanisms of Aging (mTOR) 03:15 - Calorie Restriction: The Most Proven Approach 06:10 - Intermittent Fasting: Benefits Beyond Weight Loss 09:05 - Mediterranean Diet: Plant-Based Longevity 12:05 - Ketogenic Diet: Metabolic Adaptation 14:50 - Common Mechanisms Across All Approaches 17:00 - Practical Implementation Strategies 20:30 - Q&A Session KEY INSIGHTS Calorie restriction of 25% showed significant reduction in biological aging markers in human studies All four dietary approaches (calorie restriction, fasting, Mediterranean, ketogenic) reduce mTOR activity, which is central to aging processes Reducing insulin levels is a key mechanism for extending healthspan across all effective longevity diets The Mediterranean diet offers longevity benefits without calorie restriction through anti-inflammatory effects and improved gut bacteria SCIENTIFIC REFERENCES The CALERIE Trial (2019-2023): Showed significant reduction in biological aging markers with 25% calorie restriction Alternate-Day Fasting Trial (2020-2023): Demonstrated reduced inflammatory markers and pro-aging amino acids ABOUT DR. SEAN HASHMI Dr. Sean Hashmi is a board-certified physician specializing in Ne https://www.youtube-nocookie.com/embed/rFJF5JBnNN4 2109 2024-09-12T12:42:16.000Z 2026-10-22T19:54:18.389Z https://longevityharbor.com/en/watch/rGD1BYD6N2Y AGEs: The Surprising Link Between our Diet and Aging [Advanced Glycation End Products] https://i.ytimg.com/vi/rGD1BYD6N2Y/hqdefault.jpg The second video in my Spring Forward Your Health series is here! In this lecture I'm diving into the world of advanced glycation end products (AGEs), hidden toxins lurking in our food and cooking methods. I'll uncover how these compounds accelerate aging and increase the risk of chronic diseases. Join me as I explore the surprising link between our diet, aging, and disease. After watching you will understand what ages are AGEs and simple changes you can make to your cooking and eating habits to protect your health. Don't let your food age you prematurely! In the coming months there will be a few lectures on various topics. Make sure you’re subscribed to be notified when they are released! I apologize for the audio issues in this lecture, we have it all sorted out for future lectures. Here is a link to download the slides from the presentation: https://orlandocvi.com/AGEs-Lecture-Slides/ Chapters 0:00 Introduction to Advanced Glycation End Products 2:44 What Are Advanced Glycation End Products? 12:38 The Damage From AGEs 17:46 How are AGEs Formed? 26:50 Inhibitors of AGEs 27:52 What foods have AGEs? 31:54 The effects of consuming AGEs 34:13 Measuring AGEs 38:42 How Cooking affects AGEs 56:53 The effects of Fasting 59:41 Receptors of AGEs 1:04:54 Supplements and Take-Home Points 1:08:11 Q&A - 1. What are your thoughts on Honey? 1:09:18 Q&A - 2. Can you please explain What Benfotiamine is? 1:11:32 Q&A - 3. Why is sourdough bread better for you? 1:12:18 Q&A - 4. Does Ghee Cause Cancer? 1:13:12 Q&A - 5. Is fasting unhealthy for Younger people? 1:14:47 Q&A - 6. Is there a way to tell if I am prematurely aging? 1:16:29 Q&A - 7. Can you lower your calcium score? 1:18:58 Q&A - 8. Where do you buy turmeric? Other videos in this series: Evolution of Cardiac Diagnostics - https://youtu.be/buzfmeTpyCw If you're interested in receiving personalized guidance through our fasting program, or would like to learn more about scheduling a consultation with me, please check out https://aristotleeducation.com. My Cardiology prac https://www.youtube-nocookie.com/embed/rGD1BYD6N2Y 4854 2024-05-30T21:00:27.000Z 2026-10-22T19:04:44.857Z https://longevityharbor.com/de/watch/rGD1BYD6N2Y AGEs: The Surprising Link Between our Diet and Aging [Advanced Glycation End Products] https://i.ytimg.com/vi/rGD1BYD6N2Y/hqdefault.jpg The second video in my Spring Forward Your Health series is here! In this lecture I'm diving into the world of advanced glycation end products (AGEs), hidden toxins lurking in our food and cooking methods. I'll uncover how these compounds accelerate aging and increase the risk of chronic diseases. Join me as I explore the surprising link between our diet, aging, and disease. After watching you will understand what ages are AGEs and simple changes you can make to your cooking and eating habits to protect your health. Don't let your food age you prematurely! In the coming months there will be a few lectures on various topics. Make sure you’re subscribed to be notified when they are released! I apologize for the audio issues in this lecture, we have it all sorted out for future lectures. Here is a link to download the slides from the presentation: https://orlandocvi.com/AGEs-Lecture-Slides/ Chapters 0:00 Introduction to Advanced Glycation End Products 2:44 What Are Advanced Glycation End Products? 12:38 The Damage From AGEs 17:46 How are AGEs Formed? 26:50 Inhibitors of AGEs 27:52 What foods have AGEs? 31:54 The effects of consuming AGEs 34:13 Measuring AGEs 38:42 How Cooking affects AGEs 56:53 The effects of Fasting 59:41 Receptors of AGEs 1:04:54 Supplements and Take-Home Points 1:08:11 Q&A - 1. What are your thoughts on Honey? 1:09:18 Q&A - 2. Can you please explain What Benfotiamine is? 1:11:32 Q&A - 3. Why is sourdough bread better for you? 1:12:18 Q&A - 4. Does Ghee Cause Cancer? 1:13:12 Q&A - 5. Is fasting unhealthy for Younger people? 1:14:47 Q&A - 6. Is there a way to tell if I am prematurely aging? 1:16:29 Q&A - 7. Can you lower your calcium score? 1:18:58 Q&A - 8. Where do you buy turmeric? Other videos in this series: Evolution of Cardiac Diagnostics - https://youtu.be/buzfmeTpyCw If you're interested in receiving personalized guidance through our fasting program, or would like to learn more about scheduling a consultation with me, please check out https://aristotleeducation.com. My Cardiology prac https://www.youtube-nocookie.com/embed/rGD1BYD6N2Y 4854 2024-05-30T21:00:27.000Z 2026-10-22T19:04:44.857Z https://longevityharbor.com/en/watch/rHoMPv4a2Pc Rapamycin: approved drug, but no funded human aging trial https://i.ytimg.com/vi/rHoMPv4a2Pc/hqdefault.jpg The description says rapamycin has been FDA-approved for over 25 years and human safety data exist, yet no company will fund the large human trials needed to test aging; one trial runs on a single donor's money. https://www.youtube-nocookie.com/embed/rHoMPv4a2Pc 97 2026-07-23T15:52:08.000Z 2026-10-22T23:23:22.134Z https://longevityharbor.com/de/watch/rHoMPv4a2Pc Rapamycin: zugelassenes Medikament, aber keine finanzierte Alterungsstudie am Menschen https://i.ytimg.com/vi/rHoMPv4a2Pc/hqdefault.jpg Laut Beschreibung ist Rapamycin seit über 25 Jahren FDA-zugelassen und es gibt Sicherheitsdaten am Menschen; doch kein Unternehmen finanziert die großen Studien zur Alterung, und eine Studie läuft allein mit Geld eines Spenders. https://www.youtube-nocookie.com/embed/rHoMPv4a2Pc 97 2026-07-23T15:52:08.000Z 2026-10-22T23:23:22.134Z https://longevityharbor.com/en/watch/rIzgXCuBDBA Podcast proposes modular, systems-based view of aging https://i.ytimg.com/vi/rIzgXCuBDBA/hqdefault.jpg In this podcast description, host Cade Archibald proposes viewing aging as a modular, systems-based process rather than a simple function of time, drawing on the Hallmarks of Aging and geroscience framework. https://www.youtube-nocookie.com/embed/rIzgXCuBDBA 1359 2026-01-21T16:01:18.000Z 2026-10-23T02:48:28.306Z https://longevityharbor.com/de/watch/rIzgXCuBDBA Podcast schlägt modulares, systembasiertes Alternsverständnis vor https://i.ytimg.com/vi/rIzgXCuBDBA/hqdefault.jpg In dieser Podcast-Beschreibung schlägt Gastgeber Cade Archibald vor, Altern als modularen, systembasierten Prozess statt als einfache Funktion der Zeit zu betrachten, gestützt auf die Hallmarks of Aging und den Geroscience-Rahmen. https://www.youtube-nocookie.com/embed/rIzgXCuBDBA 1359 2026-01-21T16:01:18.000Z 2026-10-23T02:48:28.306Z https://longevityharbor.com/en/watch/rKsRd67frXc Dog ageing study description: beagle blood, RNA and protein keywords https://i.ytimg.com/vi/rKsRd67frXc/hqdefault.jpg The description links a paper on ageing in beagles and lists keywords on blood, RNA sequencing, proteomics, DNA repair, inflammation and ageing hallmarks. It gives no results, numbers or design details. https://www.youtube-nocookie.com/embed/rKsRd67frXc 290 2025-12-27T06:28:28.000Z 2026-10-23T03:09:21.034Z https://longevityharbor.com/de/watch/rKsRd67frXc Beschreibung einer Hunde-Alterungsstudie: Beagle-Blut, RNA- und Protein-Stichworte https://i.ytimg.com/vi/rKsRd67frXc/hqdefault.jpg Die Beschreibung verlinkt eine Arbeit zum Altern bei Beagles und nennt Stichworte zu Blut, RNA-Sequenzierung, Proteomik, DNA-Reparatur, Entzündung und Alternsmerkmalen. Ergebnisse, Zahlen oder Studiendesign nennt sie nicht. https://www.youtube-nocookie.com/embed/rKsRd67frXc 290 2025-12-27T06:28:28.000Z 2026-10-23T03:09:21.034Z https://longevityharbor.com/en/watch/rQsMRjAwcFo Fasting for health and longevity with Dr. Jason Fung, MD — Diet Doctor Podcast https://i.ytimg.com/vi/rQsMRjAwcFo/hqdefault.jpg If fasting has been around since the beginning of time, why is it so controversial? Dr. Jason Fung has a different perspective. When done right, fasting should not be controversial at all. In fact, it should be one of our most powerful tools for treating insulin resistance, metabolic syndrome, obesity and diabetes. He also believes insulin resistance has an even further-reaching impact on our health affecting our risk of cancer and our chance for longevity. As the foremost expert on fasting, Dr. Fung has a perspective we can all learn from. Subscribe to our channel if you don't want to miss any of our videos: https://www.youtube.com/c/DietDoctorVideo?sub_confirmation=1 Or start your free trial to get access to our podcasts before they are published here: http://dietdoctor.com/new-member/video?utm_source=youtube&utm_medium=referral&utm_campaign=ytpodcast About us: DietDoctor.com is the world's number one low-carb site. Follow us for delicious recipes, meal plans, and tools to make your low-carb and keto lifestyle simple. But this YouTube channel does not contain all our videos! Visit our website https://www.dietdoctor.com Instagram: https://www.instagram.com/diet_doctor Facebook: https://www.facebook.com/TheDietDoctor https://www.youtube-nocookie.com/embed/rQsMRjAwcFo 3578 2019-07-02T15:11:29.000Z 2026-10-22T17:43:37.723Z https://longevityharbor.com/de/watch/rQsMRjAwcFo Fasting for health and longevity with Dr. Jason Fung, MD — Diet Doctor Podcast https://i.ytimg.com/vi/rQsMRjAwcFo/hqdefault.jpg If fasting has been around since the beginning of time, why is it so controversial? Dr. Jason Fung has a different perspective. When done right, fasting should not be controversial at all. In fact, it should be one of our most powerful tools for treating insulin resistance, metabolic syndrome, obesity and diabetes. He also believes insulin resistance has an even further-reaching impact on our health affecting our risk of cancer and our chance for longevity. As the foremost expert on fasting, Dr. Fung has a perspective we can all learn from. Subscribe to our channel if you don't want to miss any of our videos: https://www.youtube.com/c/DietDoctorVideo?sub_confirmation=1 Or start your free trial to get access to our podcasts before they are published here: http://dietdoctor.com/new-member/video?utm_source=youtube&utm_medium=referral&utm_campaign=ytpodcast About us: DietDoctor.com is the world's number one low-carb site. Follow us for delicious recipes, meal plans, and tools to make your low-carb and keto lifestyle simple. But this YouTube channel does not contain all our videos! Visit our website https://www.dietdoctor.com Instagram: https://www.instagram.com/diet_doctor Facebook: https://www.facebook.com/TheDietDoctor https://www.youtube-nocookie.com/embed/rQsMRjAwcFo 3578 2019-07-02T15:11:29.000Z 2026-10-22T17:43:37.723Z https://longevityharbor.com/en/watch/rTmopv-FGGU Fasting Mimicking Diet described: five-day protocol, protein advice and 12-hour eating window https://i.ytimg.com/vi/rTmopv-FGGU/hqdefault.jpg The description presents the Fasting Mimicking Diet as a five-day, plant-based, low-calorie and low-protein protocol by Valter Longo, plus protein advice by age and a 12-hour eating window; it reports no safety data. https://www.youtube-nocookie.com/embed/rTmopv-FGGU 592 2026-06-09T22:30:33.000Z 2026-10-23T00:05:04.179Z https://longevityharbor.com/de/watch/rTmopv-FGGU Fasting-Mimicking-Diät beschrieben: Fünf-Tage-Protokoll, Proteinempfehlung und 12-Stunden-Essensfens https://i.ytimg.com/vi/rTmopv-FGGU/hqdefault.jpg Die Beschreibung stellt die Fasting-Mimicking-Diät als fünftägiges, pflanzenbasiertes Protokoll mit wenigen Kalorien und wenig Protein von Valter Longo vor, dazu Proteinempfehlungen nach Alter und ein 12-Stunden-Essensfenster; Sicherheitsdaten nennt sie nicht. https://www.youtube-nocookie.com/embed/rTmopv-FGGU 592 2026-06-09T22:30:33.000Z 2026-10-23T00:05:04.179Z https://longevityharbor.com/en/watch/rVA4CO4hsdo Video description: foods for seniors and nutrition from age 60 https://i.ytimg.com/vi/rVA4CO4hsdo/hqdefault.jpg The description says the video covers foods for seniors, vitamins and minerals from age 60, muscle and bone strength, malnutrition and energy. It gives no specific foods, nutrients or results. https://www.youtube-nocookie.com/embed/rVA4CO4hsdo 227 2026-06-30T09:15:13.000Z 2026-10-22T23:41:59.783Z https://longevityharbor.com/de/watch/rVA4CO4hsdo Videobeschreibung: Lebensmittel für Senioren und Ernährung ab 60 https://i.ytimg.com/vi/rVA4CO4hsdo/hqdefault.jpg Laut Beschreibung behandelt das Video Lebensmittel für Senioren, Vitamine und Mineralstoffe ab 60, Muskel- und Knochenkraft, Mangelernährung und Energie. Konkrete Lebensmittel, Nährstoffe oder Ergebnisse nennt sie nicht. https://www.youtube-nocookie.com/embed/rVA4CO4hsdo 227 2026-06-30T09:15:13.000Z 2026-10-22T23:41:59.783Z https://longevityharbor.com/en/watch/rYgmcUMSpRk The Power of Urolithin A for Cellular Energy and Longevity https://i.ytimg.com/vi/rYgmcUMSpRk/hqdefault.jpg This presentation features Jennifer Scheinman, MS, RDN, CDN, Senior Manager of Health Sciences at Timeline. Mitochondria power every cell in the body, yet their function naturally declines with age. In this session, Jennifer Scheinman explores the science of Urolithin A, how it supports mitochondrial health through mitophagy, and what the latest research reveals about its role in healthy aging, energy, and muscle function. Presenter: Jennifer Scheinman, MS, RDN, CDN – Senior Manager of Health Sciences, Timeline Full session replay notes: https://functionalmedicinecoaching.org/blog/urolithin-a-timeline/ #Longevity #MitochondrialHealth #UrolithinA #Timeline #HealthyAging #FunctionalMedicine #healthcoachingtips Chapters: 00:00 Introduction & Guest Bio 00:56 Mitochondrial Health & Longevity Overview 01:28 The 12 Biological Hallmarks of Aging 02:54 Why Mitochondria Are the CEOs of the Cell 05:00 Understanding Mitophagy: Cellular Quality Control 06:54 What Is Urolithin A & Mitopure? 08:43 Why Diet Alone Isn't Enough for Urolithin A 10:11 Clinical Data: Activating Mitophagy in Humans 12:51 Improving Muscle Strength & Endurance 13:41 Urolithin A Benefits for Athletes & Recovery 15:18 Reversing Immune Aging with Urolithin A 17:34 Skin Aging: Cellular Renewal & UV Protection 21:51 Quality Control, FDA GRAS & NSF Certification 24:02 Recommended Dosing & Product Formulations 26:03 Timeline Nutrition DTC & Pro Line Overview 27:35 Expert Endorsements & Real-World Results 28:31 Q&A: Minimum Effective Dose & Delivery Methods 29:48 Closing Remarks & Special Offers https://www.youtube-nocookie.com/embed/rYgmcUMSpRk 1903 2026-07-30T19:59:55.000Z 2026-10-22T19:04:37.568Z https://longevityharbor.com/de/watch/rYgmcUMSpRk The Power of Urolithin A for Cellular Energy and Longevity https://i.ytimg.com/vi/rYgmcUMSpRk/hqdefault.jpg This presentation features Jennifer Scheinman, MS, RDN, CDN, Senior Manager of Health Sciences at Timeline. Mitochondria power every cell in the body, yet their function naturally declines with age. In this session, Jennifer Scheinman explores the science of Urolithin A, how it supports mitochondrial health through mitophagy, and what the latest research reveals about its role in healthy aging, energy, and muscle function. Presenter: Jennifer Scheinman, MS, RDN, CDN – Senior Manager of Health Sciences, Timeline Full session replay notes: https://functionalmedicinecoaching.org/blog/urolithin-a-timeline/ #Longevity #MitochondrialHealth #UrolithinA #Timeline #HealthyAging #FunctionalMedicine #healthcoachingtips Chapters: 00:00 Introduction & Guest Bio 00:56 Mitochondrial Health & Longevity Overview 01:28 The 12 Biological Hallmarks of Aging 02:54 Why Mitochondria Are the CEOs of the Cell 05:00 Understanding Mitophagy: Cellular Quality Control 06:54 What Is Urolithin A & Mitopure? 08:43 Why Diet Alone Isn't Enough for Urolithin A 10:11 Clinical Data: Activating Mitophagy in Humans 12:51 Improving Muscle Strength & Endurance 13:41 Urolithin A Benefits for Athletes & Recovery 15:18 Reversing Immune Aging with Urolithin A 17:34 Skin Aging: Cellular Renewal & UV Protection 21:51 Quality Control, FDA GRAS & NSF Certification 24:02 Recommended Dosing & Product Formulations 26:03 Timeline Nutrition DTC & Pro Line Overview 27:35 Expert Endorsements & Real-World Results 28:31 Q&A: Minimum Effective Dose & Delivery Methods 29:48 Closing Remarks & Special Offers https://www.youtube-nocookie.com/embed/rYgmcUMSpRk 1903 2026-07-30T19:59:55.000Z 2026-10-22T19:04:37.568Z https://longevityharbor.com/en/watch/ra5b7_hYtH8 Caloric Restriction: A Key to Longevity with Rozalyn Anderson https://i.ytimg.com/vi/ra5b7_hYtH8/hqdefault.jpg In this conversation, Rozalyn Anderson and Martin explore the complexities of aging, the impact of caloric restriction on longevity, and the scientific journey that led Rozalyn to her current research. They discuss the intersection of aging and disease, the role of adipose tissue, and the importance of understanding aging in the context of health and disease. The conversation highlights the significance of caloric restriction studies in both animal models and humans, emphasizing the need for a deeper understanding of the aging process. In this conversation, Rozalyn Anderson discusses the implications of caloric restriction studies, the role of GLP-1 in metabolic health, and the challenges of aging in the context of obesity. She highlights the significance of senescent cells in aging and the potential of stem cell therapies. The discussion also touches on the need for more geriatricians and the importance of investing in aging research and healthcare to improve outcomes for older adults. Stay tuned for updates from Longevity Summit Dublin | July 2-4 | Trinity College Dublin Takeaways from this episode - Aging is often perceived negatively, but it brings wisdom and experience. - Caloric restriction can delay aging and improve survival rates. - The study of yeast has provided significant insights into aging. - Geroscience aims to understand the relationship between aging and diseases. - Aging is a gradual decline in bodily systems. - Inflammation increases with age, affecting health responses. - Adipose tissue plays a crucial role in overall health. - Research in monkeys can provide parallels to human aging. - Caloric restriction has been shown to have non-permissive effects on tumor growth. - Understanding aging can lead to better treatments for age-related diseases. Caloric restriction studies show promise but face compliance challenges. - The biology of aging is complex and requires extensive research. - GLP-1 has fascinating implications for metabolic health. - Obesity complicates aging but is not the so https://www.youtube-nocookie.com/embed/ra5b7_hYtH8 2128 2025-05-08T01:03:01.000Z 2026-10-22T17:43:38.420Z https://longevityharbor.com/de/watch/ra5b7_hYtH8 Caloric Restriction: A Key to Longevity with Rozalyn Anderson https://i.ytimg.com/vi/ra5b7_hYtH8/hqdefault.jpg In this conversation, Rozalyn Anderson and Martin explore the complexities of aging, the impact of caloric restriction on longevity, and the scientific journey that led Rozalyn to her current research. They discuss the intersection of aging and disease, the role of adipose tissue, and the importance of understanding aging in the context of health and disease. The conversation highlights the significance of caloric restriction studies in both animal models and humans, emphasizing the need for a deeper understanding of the aging process. In this conversation, Rozalyn Anderson discusses the implications of caloric restriction studies, the role of GLP-1 in metabolic health, and the challenges of aging in the context of obesity. She highlights the significance of senescent cells in aging and the potential of stem cell therapies. The discussion also touches on the need for more geriatricians and the importance of investing in aging research and healthcare to improve outcomes for older adults. Stay tuned for updates from Longevity Summit Dublin | July 2-4 | Trinity College Dublin Takeaways from this episode - Aging is often perceived negatively, but it brings wisdom and experience. - Caloric restriction can delay aging and improve survival rates. - The study of yeast has provided significant insights into aging. - Geroscience aims to understand the relationship between aging and diseases. - Aging is a gradual decline in bodily systems. - Inflammation increases with age, affecting health responses. - Adipose tissue plays a crucial role in overall health. - Research in monkeys can provide parallels to human aging. - Caloric restriction has been shown to have non-permissive effects on tumor growth. - Understanding aging can lead to better treatments for age-related diseases. Caloric restriction studies show promise but face compliance challenges. - The biology of aging is complex and requires extensive research. - GLP-1 has fascinating implications for metabolic health. - Obesity complicates aging but is not the so https://www.youtube-nocookie.com/embed/ra5b7_hYtH8 2128 2025-05-08T01:03:01.000Z 2026-10-22T17:43:38.420Z https://longevityharbor.com/en/watch/rbgEiH9hSPM Video description: six sleep patterns linked to aging hallmarks in 93,000 people https://i.ytimg.com/vi/rbgEiH9hSPM/hqdefault.jpg The description says six sleep patterns were ranked by their link to nine hallmarks of aging, using one week of wrist data and seven years of medical records from 93,000 people. It reports associations, not causes. https://www.youtube-nocookie.com/embed/rbgEiH9hSPM 806 2026-09-11T13:44:39.000Z 2026-10-22T22:18:23.326Z https://longevityharbor.com/de/watch/rbgEiH9hSPM Videobeschreibung: sechs Schlafmuster mit Bezug zu Alternsmerkmalen bei 93.000 Menschen https://i.ytimg.com/vi/rbgEiH9hSPM/hqdefault.jpg Laut Beschreibung wurden sechs Schlafmuster nach ihrem Zusammenhang mit neun Alternsmerkmalen geordnet, anhand einer Woche Handgelenkdaten und sieben Jahren Krankenakten von 93.000 Menschen. Berichtet werden Zusammenhänge, keine Ursachen. https://www.youtube-nocookie.com/embed/rbgEiH9hSPM 806 2026-09-11T13:44:39.000Z 2026-10-22T22:18:23.326Z https://longevityharbor.com/en/watch/reM6peUSTCI Live talk outlines a female longevity framework: testing, tracking and advanced therapies https://i.ytimg.com/vi/reM6peUSTCI/hqdefault.jpg The creator describes a framework covering nervous system, sleep, muscle and bone, cardiovascular fitness, nutrition, toxins, gut health, hormones, advanced therapies and personalized testing, and says women should not automatically reduce training or follow rigid cycle-based protocols. https://www.youtube-nocookie.com/embed/reM6peUSTCI 3560 2026-07-18T16:00:27.000Z 2026-10-22T23:29:45.185Z https://longevityharbor.com/de/watch/reM6peUSTCI Live-Talk stellt einen Rahmen für weibliche Langlebigkeit vor: Testen, Verfolgen und fortgeschritten https://i.ytimg.com/vi/reM6peUSTCI/hqdefault.jpg Die Erstellerin beschreibt einen Rahmen zu Nervensystem, Schlaf, Muskeln und Knochen, Herz-Kreislauf-Fitness, Ernährung, Toxinen, Darmgesundheit, Hormonen, fortgeschrittenen Therapien und personalisierten Tests; Frauen sollten nicht automatisch ihr Training reduzieren oder starre zyklusbasierte Protokolle befolgen. https://www.youtube-nocookie.com/embed/reM6peUSTCI 3560 2026-07-18T16:00:27.000Z 2026-10-22T23:29:45.185Z https://longevityharbor.com/en/watch/rjI6kI1soMQ Podcast description: fasting and calorie restriction alongside cancer treatment https://i.ytimg.com/vi/rjI6kI1soMQ/hqdefault.jpg The description says nutrition and fasting protocols may play a complementary role when guided by data and integrated with standard care, and that patients should bring evidence to their oncologist for a shared decision. https://www.youtube-nocookie.com/embed/rjI6kI1soMQ 111 2026-09-26T12:00:33.000Z 2026-10-22T21:48:29.141Z https://longevityharbor.com/de/watch/rjI6kI1soMQ Podcast-Beschreibung: Fasten und Kalorienrestriktion begleitend zur Krebstherapie https://i.ytimg.com/vi/rjI6kI1soMQ/hqdefault.jpg Laut Beschreibung können Ernährungs- und Fastenprotokolle eine ergänzende Rolle spielen, wenn sie datengestützt und in die Standardversorgung eingebunden sind; Patientinnen und Patienten sollten Belege in das Gespräch mit der Onkologin oder dem Onkologen einbringen, um gemeinsam zu entscheiden. https://www.youtube-nocookie.com/embed/rjI6kI1soMQ 111 2026-09-26T12:00:33.000Z 2026-10-22T21:48:29.141Z https://longevityharbor.com/en/watch/rl6N3i5Ve0s When Mitochondrial DNA goes Nuclear https://i.ytimg.com/vi/rl6N3i5Ve0s/hqdefault.jpg The original review: https://doi.org/10.1016/j.arr.2025.102892 Key-words: 8-oxo-deoxyguanosine, aging, altered cellular communication, apoptosis, BAX/BAK pore, biological aging, carcinogenesis, cellular senescence, chromosomal instability, cognitive decline, cGAS-STING, D-loop, DNA double-strand breaks, DNA repair, DNA methylation, endosymbiosis, epigenetic alterations, evolutionary conservation, gasdermin D, genomic instability, geroscience, hallmarks of aging, horizontal gene transfer, humanin, immunosenescence, inflammaging, inflammation, lifespan, micronuclei, mitochondrial dysfunction, mitochondrial-derived peptides, mitochondrial-nuclear communication, mitophagy, MOTS-c, mtDNA, neurodegeneration, non-homologous end joining, NUMT, NUMTogenesis, oncogenesis, oxidative stress, pseudogenes, rapamycin, reactive oxygen species, resilience, retrograde signaling, somatic mutations, telomere attrition, transposable elements, whole-genome sequencing https://www.youtube-nocookie.com/embed/rl6N3i5Ve0s 349 2025-09-05T13:05:51.000Z 2026-10-22T19:54:20.398Z https://longevityharbor.com/de/watch/rl6N3i5Ve0s When Mitochondrial DNA goes Nuclear https://i.ytimg.com/vi/rl6N3i5Ve0s/hqdefault.jpg The original review: https://doi.org/10.1016/j.arr.2025.102892 Key-words: 8-oxo-deoxyguanosine, aging, altered cellular communication, apoptosis, BAX/BAK pore, biological aging, carcinogenesis, cellular senescence, chromosomal instability, cognitive decline, cGAS-STING, D-loop, DNA double-strand breaks, DNA repair, DNA methylation, endosymbiosis, epigenetic alterations, evolutionary conservation, gasdermin D, genomic instability, geroscience, hallmarks of aging, horizontal gene transfer, humanin, immunosenescence, inflammaging, inflammation, lifespan, micronuclei, mitochondrial dysfunction, mitochondrial-derived peptides, mitochondrial-nuclear communication, mitophagy, MOTS-c, mtDNA, neurodegeneration, non-homologous end joining, NUMT, NUMTogenesis, oncogenesis, oxidative stress, pseudogenes, rapamycin, reactive oxygen species, resilience, retrograde signaling, somatic mutations, telomere attrition, transposable elements, whole-genome sequencing https://www.youtube-nocookie.com/embed/rl6N3i5Ve0s 349 2025-09-05T13:05:51.000Z 2026-10-22T19:54:20.398Z https://longevityharbor.com/en/watch/rnIA7U-bFkY Periodic fasting has the same longevity benefit as caloric restriction (and without emaciation) https://i.ytimg.com/vi/rnIA7U-bFkY/hqdefault.jpg Calorie restriction, a promising strategy to extend lifespan, causes significant weight loss in mice. However, this dietary regimen is very difficult to adhere to. Interestingly, mice that are fed on an intermittent fasting schedule adjust to their restricted regimen and, in the end, tend to weigh as much as mice fed on a normal schedule, but they exhibit many of the physiological responses – including induction of autophagy – as calorie-restricted mice. In this clip, Dr. Guido Kroemer describes how intermittent fasting recapitulates the life-extension benefits of caloric restriction without some of the drawbacks. This clip was taken from the FoundMyFitness interview with Dr. Guido Kroemer found at https://www.youtube.com/watch?v=Gm626MgpveI Original episode published on July 31, 2017 ⏳ #aging #autophagy #cancer 🧫 https://www.youtube-nocookie.com/embed/rnIA7U-bFkY 195 2019-04-07T22:46:43.000Z 2026-10-22T17:43:38.438Z https://longevityharbor.com/de/watch/rnIA7U-bFkY Periodic fasting has the same longevity benefit as caloric restriction (and without emaciation) https://i.ytimg.com/vi/rnIA7U-bFkY/hqdefault.jpg Calorie restriction, a promising strategy to extend lifespan, causes significant weight loss in mice. However, this dietary regimen is very difficult to adhere to. Interestingly, mice that are fed on an intermittent fasting schedule adjust to their restricted regimen and, in the end, tend to weigh as much as mice fed on a normal schedule, but they exhibit many of the physiological responses – including induction of autophagy – as calorie-restricted mice. In this clip, Dr. Guido Kroemer describes how intermittent fasting recapitulates the life-extension benefits of caloric restriction without some of the drawbacks. This clip was taken from the FoundMyFitness interview with Dr. Guido Kroemer found at https://www.youtube.com/watch?v=Gm626MgpveI Original episode published on July 31, 2017 ⏳ #aging #autophagy #cancer 🧫 https://www.youtube-nocookie.com/embed/rnIA7U-bFkY 195 2019-04-07T22:46:43.000Z 2026-10-22T17:43:38.438Z https://longevityharbor.com/en/watch/rpmo2PlGDKc Senolysis of Senescent Cells Modulates Lung Fibroblasts | Aging-US https://i.ytimg.com/vi/rpmo2PlGDKc/hqdefault.jpg Aging-US #published this #trending research #paper on June 29, 2024 in Volume 16, Issue 13, entitled, “Modulating in vitro lung fibroblast activation via senolysis of senescent human alveolar epithelial cells" by researchers from the AbbVie Bioresearch Center, Worcester, MA; Department of Biology, Northeastern University, Boston, MA; AbbVie Inc., North Chicago, IL. @NortheasternCOS @Northeastern #aging #lungs #fibrosis #cells #epithelial #senescence #research #openaccess #openscience #peerreview #journal #publication #publishing #trending #meded DOI - https://doi.org/10.18632/aging.205994 Corresponding author - Tovah A. Day - t.day@northeastern.edu Abstract Idiopathic pulmonary fibrosis (IPF) is an age-related disease with poor prognosis and limited therapeutic options. Activation of lung fibroblasts and differentiation to myofibroblasts are the principal effectors of disease pathology, but damage and senescence of alveolar epithelial cells, specifically type II (ATII) cells, has recently been identified as a potential trigger event for the progressive disease cycle. Targeting ATII senescence and the senescence-associated secretory phenotype (SASP) is an attractive therapeutic strategy; however, translatable primary human cell models that enable mechanistic studies and drug development are lacking. Here, we describe a novel system of conditioned medium (CM) transfer from bleomycin-induced senescent primary alveolar epithelial cells (AEC) onto normal human lung fibroblasts (NHLF) that demonstrates an enhanced fibrotic transcriptional and secretory phenotype compared to non-senescent AEC CM treatment or direct bleomycin damage of the NHLFs. In this system, the bleomycin-treated AECs exhibit classical hallmarks of cellular senescence, including SASP and a gene expression profile that resembles aberrant epithelial cells of the IPF lung. Fibroblast activation by CM transfer is attenuated by pre-treatment of senescent AECs with the senolytic Navitoclax and AD80, but not with the standard of care agent Nintedanib https://www.youtube-nocookie.com/embed/rpmo2PlGDKc 122 2024-07-15T20:18:56.000Z 2026-10-22T19:21:23.299Z https://longevityharbor.com/de/watch/rpmo2PlGDKc Senolysis of Senescent Cells Modulates Lung Fibroblasts | Aging-US https://i.ytimg.com/vi/rpmo2PlGDKc/hqdefault.jpg Aging-US #published this #trending research #paper on June 29, 2024 in Volume 16, Issue 13, entitled, “Modulating in vitro lung fibroblast activation via senolysis of senescent human alveolar epithelial cells" by researchers from the AbbVie Bioresearch Center, Worcester, MA; Department of Biology, Northeastern University, Boston, MA; AbbVie Inc., North Chicago, IL. @NortheasternCOS @Northeastern #aging #lungs #fibrosis #cells #epithelial #senescence #research #openaccess #openscience #peerreview #journal #publication #publishing #trending #meded DOI - https://doi.org/10.18632/aging.205994 Corresponding author - Tovah A. Day - t.day@northeastern.edu Abstract Idiopathic pulmonary fibrosis (IPF) is an age-related disease with poor prognosis and limited therapeutic options. Activation of lung fibroblasts and differentiation to myofibroblasts are the principal effectors of disease pathology, but damage and senescence of alveolar epithelial cells, specifically type II (ATII) cells, has recently been identified as a potential trigger event for the progressive disease cycle. Targeting ATII senescence and the senescence-associated secretory phenotype (SASP) is an attractive therapeutic strategy; however, translatable primary human cell models that enable mechanistic studies and drug development are lacking. Here, we describe a novel system of conditioned medium (CM) transfer from bleomycin-induced senescent primary alveolar epithelial cells (AEC) onto normal human lung fibroblasts (NHLF) that demonstrates an enhanced fibrotic transcriptional and secretory phenotype compared to non-senescent AEC CM treatment or direct bleomycin damage of the NHLFs. In this system, the bleomycin-treated AECs exhibit classical hallmarks of cellular senescence, including SASP and a gene expression profile that resembles aberrant epithelial cells of the IPF lung. Fibroblast activation by CM transfer is attenuated by pre-treatment of senescent AECs with the senolytic Navitoclax and AD80, but not with the standard of care agent Nintedanib https://www.youtube-nocookie.com/embed/rpmo2PlGDKc 122 2024-07-15T20:18:56.000Z 2026-10-22T19:21:23.299Z https://longevityharbor.com/en/watch/rrqk5HrljQ0 Phenotypic and Epigenetic Clocks for Aging and Mortality | Aging-US https://i.ytimg.com/vi/rrqk5HrljQ0/hqdefault.jpg Aging-US #published this #trending review on August 30, 2024 in Volume 16, Issue 17, entitled “A systematic review of phenotypic and epigenetic clocks used for aging and mortality quantification in humans" by researchers from Verseon International Corp., Fremont, CA; Department of IST, University of Houston, Houston, TX; Department of Engineering Management and Systems Engineering, Missouri University of Science and Technology, Rolla, MO. @UHEngineering @MissouriSandT #aging #machinelearning #biomarkers #mortality #epigenetics #DNA #review #research #openaccess #openscience #peerreview #journal #publishing #meded DOI - https://doi.org/10.18632/aging.206098 Corresponding author - Brandon Warner - bwarner@verseon.com Abstract Aging is the leading driver of disease in humans and has profound impacts on mortality. Biological clocks are used to measure the aging process in the hopes of identifying possible interventions. Biological clocks may be categorized as phenotypic or epigenetic, where phenotypic clocks use easily measurable clinical biomarkers and epigenetic clocks use cellular methylation data. In recent years, methylation clocks have attained phenomenal performance when predicting chronological age and have been linked to various age-related diseases. Additionally, phenotypic clocks have been proven to be able to predict mortality better than chronological age, providing intracellular insights into the aging process. This review aimed to systematically survey all proposed epigenetic and phenotypic clocks to date, excluding mitotic clocks (i.e., cancer risk clocks) and those that were modeled using non-human samples. We reported the predictive performance of 33 clocks and outlined the statistical or machine learning techniques used. We also reported the most influential clinical measurements used in the included phenotypic clocks. Our findings provide a systematic reporting of the last decade of biological clock research and indicate possible avenues for future research. Sign up for free Altmetric alerts https://www.youtube-nocookie.com/embed/rrqk5HrljQ0 110 2024-11-19T18:00:40.000Z 2026-10-22T18:54:04.107Z https://longevityharbor.com/de/watch/rrqk5HrljQ0 Phenotypic and Epigenetic Clocks for Aging and Mortality | Aging-US https://i.ytimg.com/vi/rrqk5HrljQ0/hqdefault.jpg Aging-US #published this #trending review on August 30, 2024 in Volume 16, Issue 17, entitled “A systematic review of phenotypic and epigenetic clocks used for aging and mortality quantification in humans" by researchers from Verseon International Corp., Fremont, CA; Department of IST, University of Houston, Houston, TX; Department of Engineering Management and Systems Engineering, Missouri University of Science and Technology, Rolla, MO. @UHEngineering @MissouriSandT #aging #machinelearning #biomarkers #mortality #epigenetics #DNA #review #research #openaccess #openscience #peerreview #journal #publishing #meded DOI - https://doi.org/10.18632/aging.206098 Corresponding author - Brandon Warner - bwarner@verseon.com Abstract Aging is the leading driver of disease in humans and has profound impacts on mortality. Biological clocks are used to measure the aging process in the hopes of identifying possible interventions. Biological clocks may be categorized as phenotypic or epigenetic, where phenotypic clocks use easily measurable clinical biomarkers and epigenetic clocks use cellular methylation data. In recent years, methylation clocks have attained phenomenal performance when predicting chronological age and have been linked to various age-related diseases. Additionally, phenotypic clocks have been proven to be able to predict mortality better than chronological age, providing intracellular insights into the aging process. This review aimed to systematically survey all proposed epigenetic and phenotypic clocks to date, excluding mitotic clocks (i.e., cancer risk clocks) and those that were modeled using non-human samples. We reported the predictive performance of 33 clocks and outlined the statistical or machine learning techniques used. We also reported the most influential clinical measurements used in the included phenotypic clocks. Our findings provide a systematic reporting of the last decade of biological clock research and indicate possible avenues for future research. Sign up for free Altmetric alerts https://www.youtube-nocookie.com/embed/rrqk5HrljQ0 110 2024-11-19T18:00:40.000Z 2026-10-22T18:54:04.107Z https://longevityharbor.com/en/watch/rxdX6k15mQw What You NEED to KNOW About MTOR | Dr. A Explains https://i.ytimg.com/vi/rxdX6k15mQw/hqdefault.jpg Consult with Dr. A- https://www.consultdranderson.com/product/vitamin-c-webinar-bundle/ Are You Accidentally Activating mTOR? 🧬🤔 mTOR controls growth, aging, and metabolism—but is yours helping or harming you? Learn how diet, fasting, and lifestyle impact mTOR and why balancing it is key for longevity. Plus, the truth about rapamycin and its potential in cancer, inflammation, and aging. ____________________________ CHAPTERS 00:00 Introduction 01:07 Discovery of mTOR & Rapamycin 02:56 Understanding mTOR Pathway 04:07 Medical Uses of Rapamycin & mTOR Inhibitors 06:55 mTOR’s Role in the Body 08:38 Balancing mTOR: Diet & Fasting 09:47 Aging, Chronic Illness & mTOR Modulation 10:56 Why Inhibit mTOR in Transplant Patients? 12:03 Lifestyle & Natural mTOR Modulation ___________________________ This video is NOT sponsored. Helpful Links CE COURSES FOR PROFESSIONALS: https://bit.ly/dra-continuingeducation Continuing Education for Professionals: consultdranderson.com Methylene Blue CE Webinar: https://www.consultdranderson.com/product/107-methylene-blue/ Probiotics Research Paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC10470842/ Connect with Dr. Anderson ~ Dr A YouTube Channel: https://www.youtube.com/channel/UC1FLIaKDzkU5Z0knDYYKyPQ Dr A Instagram: https://www.instagram.com/draonline/ Dr A Links: https://linktr.ee/DrAonline Dr A Website: https://dranow.com/ ____________________________ #integrativemedicine #functionalmedicine #doctorsofinstagram #doctor #nmd #nd #naturopathicdoctor #naturopathy #Longevity #AntiAging #mTOR #Rapamycin #CellHealth #Autophagy #DoctorExplains ____________________________ INTEGRATIVE MEDICINE REFERRAL LINKS (Use these to find providers.) [For your reference only – no referral or implication of professional superiority is claimed or intended.] NAEM (Environmental Medicine) Providers: https://envmedicine.com/find-a-provider/ US Naturopathic Physicians: https://naturopathic.org/search/default.asp?m=radius Canadian Naturopathic Physicians: https://www.cand.ca/findm https://www.youtube-nocookie.com/embed/rxdX6k15mQw 772 2025-02-20T14:01:07.000Z 2026-10-22T19:54:21.411Z https://longevityharbor.com/de/watch/rxdX6k15mQw What You NEED to KNOW About MTOR | Dr. A Explains https://i.ytimg.com/vi/rxdX6k15mQw/hqdefault.jpg Consult with Dr. A- https://www.consultdranderson.com/product/vitamin-c-webinar-bundle/ Are You Accidentally Activating mTOR? 🧬🤔 mTOR controls growth, aging, and metabolism—but is yours helping or harming you? Learn how diet, fasting, and lifestyle impact mTOR and why balancing it is key for longevity. Plus, the truth about rapamycin and its potential in cancer, inflammation, and aging. ____________________________ CHAPTERS 00:00 Introduction 01:07 Discovery of mTOR & Rapamycin 02:56 Understanding mTOR Pathway 04:07 Medical Uses of Rapamycin & mTOR Inhibitors 06:55 mTOR’s Role in the Body 08:38 Balancing mTOR: Diet & Fasting 09:47 Aging, Chronic Illness & mTOR Modulation 10:56 Why Inhibit mTOR in Transplant Patients? 12:03 Lifestyle & Natural mTOR Modulation ___________________________ This video is NOT sponsored. Helpful Links CE COURSES FOR PROFESSIONALS: https://bit.ly/dra-continuingeducation Continuing Education for Professionals: consultdranderson.com Methylene Blue CE Webinar: https://www.consultdranderson.com/product/107-methylene-blue/ Probiotics Research Paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC10470842/ Connect with Dr. Anderson ~ Dr A YouTube Channel: https://www.youtube.com/channel/UC1FLIaKDzkU5Z0knDYYKyPQ Dr A Instagram: https://www.instagram.com/draonline/ Dr A Links: https://linktr.ee/DrAonline Dr A Website: https://dranow.com/ ____________________________ #integrativemedicine #functionalmedicine #doctorsofinstagram #doctor #nmd #nd #naturopathicdoctor #naturopathy #Longevity #AntiAging #mTOR #Rapamycin #CellHealth #Autophagy #DoctorExplains ____________________________ INTEGRATIVE MEDICINE REFERRAL LINKS (Use these to find providers.) [For your reference only – no referral or implication of professional superiority is claimed or intended.] NAEM (Environmental Medicine) Providers: https://envmedicine.com/find-a-provider/ US Naturopathic Physicians: https://naturopathic.org/search/default.asp?m=radius Canadian Naturopathic Physicians: https://www.cand.ca/findm https://www.youtube-nocookie.com/embed/rxdX6k15mQw 772 2025-02-20T14:01:07.000Z 2026-10-22T19:54:21.411Z https://longevityharbor.com/en/watch/rybcZjb4O6g Video description on biological age, epigenetic clocks and lifestyle claims https://i.ytimg.com/vi/rybcZjb4O6g/hqdefault.jpg The description says the video explains biological versus chronological age, epigenetic aging clocks, longevity science and whether aging can be slowed or reversed, and links sleep, stress, exercise, nutrition and lifestyle habits to how fast the body ages. No results are reported. https://www.youtube-nocookie.com/embed/rybcZjb4O6g 114 2026-05-13T18:00:50.000Z 2026-10-23T01:05:01.974Z https://longevityharbor.com/de/watch/rybcZjb4O6g Videobeschreibung zu biologischem Alter, epigenetischen Uhren und Lebensstil-Aussagen https://i.ytimg.com/vi/rybcZjb4O6g/hqdefault.jpg Laut Beschreibung erklärt das Video biologisches versus chronologisches Alter, epigenetische Altersuhren, Langlebigkeitsforschung und ob Altern verlangsamt oder umgekehrt werden kann; Schlaf, Stress, Bewegung, Ernährung und Lebensstil werden damit verknüpft, wie schnell der Körper altert. Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/rybcZjb4O6g 114 2026-05-13T18:00:50.000Z 2026-10-23T01:05:01.974Z https://longevityharbor.com/en/watch/s0NpaM1xrWg Podcast reality check: biological aging clocks, mTOR and rapamycin with Dr. Matt Kaeberlein https://i.ytimg.com/vi/s0NpaM1xrWg/hqdefault.jpg In this podcast description, Drs. Nisha and Vikas Patel say they discuss with aging researcher Dr. Matt Kaeberlein why most biological aging clocks fall short, what mTOR does, how rapamycin works and why it is widely misunderstood, and what the description lists as improving healthspan. https://www.youtube-nocookie.com/embed/s0NpaM1xrWg 4545 2025-12-25T13:45:14.000Z 2026-10-23T03:09:59.922Z https://longevityharbor.com/de/watch/s0NpaM1xrWg Podcast-Realitätscheck: biologische Altersuhren, mTOR und Rapamycin mit Dr. Matt Kaeberlein https://i.ytimg.com/vi/s0NpaM1xrWg/hqdefault.jpg In dieser Podcast-Beschreibung geben Drs. Nisha und Vikas Patel an, mit dem Alternsforscher Dr. Matt Kaeberlein zu besprechen, warum die meisten biologischen Altersuhren unzureichend sind, was mTOR tut, wie Rapamycin wirkt und warum es weithin missverstanden wird, sowie was die Beschreibung als gesundheitsfördernd für die Gesundheitsspanne nennt. https://www.youtube-nocookie.com/embed/s0NpaM1xrWg 4545 2025-12-25T13:45:14.000Z 2026-10-23T03:09:59.922Z https://longevityharbor.com/en/watch/s8RTDUQpWa0 Senescence, Senolytics, and IPF https://i.ytimg.com/vi/s8RTDUQpWa0/hqdefault.jpg All eyes are on this season’s new developments in ILD management and diagnosis. Supported by an educational grant from Boehringer Ingelheim Pharmaceuticals, Inc. For more, visit PILOTforPulmonary.org/ https://www.youtube-nocookie.com/embed/s8RTDUQpWa0 264 2019-11-26T03:36:36.000Z 2026-10-23T02:56:02.460Z https://longevityharbor.com/de/watch/s8RTDUQpWa0 Senescence, Senolytics, and IPF https://i.ytimg.com/vi/s8RTDUQpWa0/hqdefault.jpg All eyes are on this season’s new developments in ILD management and diagnosis. Supported by an educational grant from Boehringer Ingelheim Pharmaceuticals, Inc. For more, visit PILOTforPulmonary.org/ https://www.youtube-nocookie.com/embed/s8RTDUQpWa0 264 2019-11-26T03:36:36.000Z 2026-10-23T02:56:02.460Z https://longevityharbor.com/en/watch/sD7ICqENEls Dr. Matt Kaeberlein Presents: Longevity science: From molecules to pets to clinical practice https://i.ytimg.com/vi/sD7ICqENEls/hqdefault.jpg Watch as Dr. Matt Kaeberlein Ph.D. speaks with SENS Research Foundation about the progress of his current projects and a variety of other longevity topics. https://www.youtube-nocookie.com/embed/sD7ICqENEls 5291 2024-06-25T16:42:34.000Z 2026-10-22T19:54:20.330Z https://longevityharbor.com/de/watch/sD7ICqENEls Dr. Matt Kaeberlein Presents: Longevity science: From molecules to pets to clinical practice https://i.ytimg.com/vi/sD7ICqENEls/hqdefault.jpg Watch as Dr. Matt Kaeberlein Ph.D. speaks with SENS Research Foundation about the progress of his current projects and a variety of other longevity topics. https://www.youtube-nocookie.com/embed/sD7ICqENEls 5291 2024-06-25T16:42:34.000Z 2026-10-22T19:54:20.330Z https://longevityharbor.com/en/watch/sFL7Fek8KqE NOVOS founder Chris Mirabile on longevity, healthspan and hallmarks of aging https://i.ytimg.com/vi/sFL7Fek8KqE/hqdefault.jpg In this podcast description, NOVOS founder Chris Mirabile says true longevity means extending healthspan or lifespan beyond what normal healthy living achieves, and describes NOVOS as targeting several aging mechanisms at once. https://www.youtube-nocookie.com/embed/sFL7Fek8KqE 2532 2026-03-06T03:57:53.000Z 2026-10-23T02:12:41.191Z https://longevityharbor.com/de/watch/sFL7Fek8KqE NOVOS-Gründer Chris Mirabile über Langlebigkeit, Healthspan und Hallmarks des Alterns https://i.ytimg.com/vi/sFL7Fek8KqE/hqdefault.jpg In dieser Podcast-Beschreibung sagt NOVOS-Gründer Chris Mirabile, echte Langlebigkeit bedeute, Healthspan oder Lebensspanne über das hinaus zu verlängern, was ein normal gesunder Lebensstil erreicht; NOVOS ziele zugleich auf mehrere Alternsmechanismen. https://www.youtube-nocookie.com/embed/sFL7Fek8KqE 2532 2026-03-06T03:57:53.000Z 2026-10-23T02:12:41.191Z https://longevityharbor.com/en/watch/sIP4wqK-D_o Nutrition and healthy ageing: what the video description says science knows https://i.ytimg.com/vi/sIP4wqK-D_o/hqdefault.jpg The description announces a first part of a longevity double episode on nutrition and healthy ageing. It names topics such as the Mediterranean diet, less meat, more fibre, protein, highly processed foods, red wine and Blue Zones, plus five everyday tips. No results are given. https://www.youtube-nocookie.com/embed/sIP4wqK-D_o 1408 2026-10-10T05:07:54.000Z 2026-10-22T20:46:16.571Z https://longevityharbor.com/de/watch/sIP4wqK-D_o Ernährung und gesundes Altern: Was die Videobeschreibung laut Wissenschaft weiß https://i.ytimg.com/vi/sIP4wqK-D_o/hqdefault.jpg Die Beschreibung kündigt einen ersten Teil einer Longevity-Doppelfolge zu Ernährung und gesundem Altern an. Genannt werden Themen wie mediterrane Ernährung, weniger Fleisch, mehr Ballaststoffe, Protein, hochverarbeitete Lebensmittel, Rotwein und Blue Zones sowie fünf Alltagstipps. Ergebnisse werden nicht genannt. https://www.youtube-nocookie.com/embed/sIP4wqK-D_o 1408 2026-10-10T05:07:54.000Z 2026-10-22T20:46:16.571Z https://longevityharbor.com/en/watch/sIyS4Wd8iEk Rapamycin for slowing of aging. What dose? What is typical schedule for rapamycin? https://i.ytimg.com/vi/sIyS4Wd8iEk/hqdefault.jpg Dr. Matt Kaeberlein explains that while organ transplant patients typically take daily rapamycin to prevent rejection, those using it for health maintenance often follow a once-weekly schedule of four to six milligrams. This lower frequency is based on anecdotal reports and trials with the related drug everolimus, which showed minimal side effects in healthy older adults. Short-term studies suggest this regimen may improve immune response to vaccines without the significant metabolic or infection risks associated with daily immunosuppression. Read the full transcript and related expert articles: https://diagnosticdetectives.com/products/rapamycin-for-slowing-of-aging-what-dose-what-is-typical-schedule-for-rapamycin-12 Related expert videos: - Rapamycin is not a miracle drug for aging. Rapamycin and mTOR in psychiatry.: https://www.youtube.com/watch?v=DkmHsPLPciE - Metformin, rapamycin for slowing of aging. 20 senolytics are in clinical trials. Results?: https://www.youtube.com/watch?v=mFlS5-G726U - Rapamycin in Alzheimer’s disease. Reputational issues in use of rapamycin.: https://www.youtube.com/watch?v=gni04m99nRA - Rapamycin and anti-aging clinical trials. How to use rapamycin safely in humans?: https://www.youtube.com/watch?v=jNxlJep1FfY - Dr. Matt Kaeberlein. Anti-aging, Longevity Expert. Biography.: https://diagnosticdetectives.com/products/dr-matt-kaeberlein-anti-aging-longevity-expert-biography-0 Other languages: this interview is dubbed in Russian, German, French, Chinese, Arabic. Diagnostic Detectives Network publishes video masterclasses for patients: in-depth, plain-language conversations with the world's leading medical experts about the diseases, treatments and decisions patients face. Free, with no advertising, sponsorship or hospital affiliation, in English and 10 other languages. Diagnostic Detectives Network also provides an independent medical second opinion service. For each patient we assemble a panel of leading specialists precisely matched to the diagnosis, from anywhere in the world. https://www.youtube-nocookie.com/embed/sIyS4Wd8iEk 691 2026-09-25T07:01:40.000Z 2026-10-22T19:04:39.718Z https://longevityharbor.com/de/watch/sIyS4Wd8iEk Rapamycin for slowing of aging. What dose? What is typical schedule for rapamycin? https://i.ytimg.com/vi/sIyS4Wd8iEk/hqdefault.jpg Dr. Matt Kaeberlein explains that while organ transplant patients typically take daily rapamycin to prevent rejection, those using it for health maintenance often follow a once-weekly schedule of four to six milligrams. This lower frequency is based on anecdotal reports and trials with the related drug everolimus, which showed minimal side effects in healthy older adults. Short-term studies suggest this regimen may improve immune response to vaccines without the significant metabolic or infection risks associated with daily immunosuppression. Read the full transcript and related expert articles: https://diagnosticdetectives.com/products/rapamycin-for-slowing-of-aging-what-dose-what-is-typical-schedule-for-rapamycin-12 Related expert videos: - Rapamycin is not a miracle drug for aging. Rapamycin and mTOR in psychiatry.: https://www.youtube.com/watch?v=DkmHsPLPciE - Metformin, rapamycin for slowing of aging. 20 senolytics are in clinical trials. Results?: https://www.youtube.com/watch?v=mFlS5-G726U - Rapamycin in Alzheimer’s disease. Reputational issues in use of rapamycin.: https://www.youtube.com/watch?v=gni04m99nRA - Rapamycin and anti-aging clinical trials. How to use rapamycin safely in humans?: https://www.youtube.com/watch?v=jNxlJep1FfY - Dr. Matt Kaeberlein. Anti-aging, Longevity Expert. Biography.: https://diagnosticdetectives.com/products/dr-matt-kaeberlein-anti-aging-longevity-expert-biography-0 Other languages: this interview is dubbed in Russian, German, French, Chinese, Arabic. Diagnostic Detectives Network publishes video masterclasses for patients: in-depth, plain-language conversations with the world's leading medical experts about the diseases, treatments and decisions patients face. Free, with no advertising, sponsorship or hospital affiliation, in English and 10 other languages. Diagnostic Detectives Network also provides an independent medical second opinion service. For each patient we assemble a panel of leading specialists precisely matched to the diagnosis, from anywhere in the world. https://www.youtube-nocookie.com/embed/sIyS4Wd8iEk 691 2026-09-25T07:01:40.000Z 2026-10-22T19:04:39.718Z https://longevityharbor.com/en/watch/sNMVEQjkU1A [Julia Majewska] Senescence upregulates PDL1 to evade immune surveillance and promote lunginflamming https://i.ytimg.com/vi/sNMVEQjkU1A/hqdefault.jpg Speaker: Julia Majewska Talk: Senescent cells up regulate PD-L1 to evade immune surveillance and promote lung inflammation Paper: p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells (Nat Cell Biology, 2024) https://www.nature.com/articles/s41556-024-01465-0 Moderator: Anna Salamero Boix (Open Box Science) https://www.youtube-nocookie.com/embed/sNMVEQjkU1A 1586 2025-08-03T22:00:56.000Z 2026-10-22T19:21:23.114Z https://longevityharbor.com/de/watch/sNMVEQjkU1A [Julia Majewska] Senescence upregulates PDL1 to evade immune surveillance and promote lunginflamming https://i.ytimg.com/vi/sNMVEQjkU1A/hqdefault.jpg Speaker: Julia Majewska Talk: Senescent cells up regulate PD-L1 to evade immune surveillance and promote lung inflammation Paper: p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells (Nat Cell Biology, 2024) https://www.nature.com/articles/s41556-024-01465-0 Moderator: Anna Salamero Boix (Open Box Science) https://www.youtube-nocookie.com/embed/sNMVEQjkU1A 1586 2025-08-03T22:00:56.000Z 2026-10-22T19:21:23.114Z https://longevityharbor.com/en/watch/sP8b72Sr_jk What REALLY Matters when taking NMN and NR supplements https://i.ytimg.com/vi/sP8b72Sr_jk/hqdefault.jpg Did you know that having excessive degraded NAD is bad for health? If you are taking NMN or NR, you must know the most important tricks to make it work for you. Watch this video till the end to learn what you can do to maximise it's benefits. @wellnessbymiri #nmn #nad #nr #health #longevity #energy #antiaging #aging #metabolism #workout #mitochondria #ATP #exercise #muscle #vo2max #lifestyle #lifestylemedicine https://www.youtube-nocookie.com/embed/sP8b72Sr_jk 167 2025-03-14T14:06:44.000Z 2026-10-22T18:43:09.984Z https://longevityharbor.com/de/watch/sP8b72Sr_jk What REALLY Matters when taking NMN and NR supplements https://i.ytimg.com/vi/sP8b72Sr_jk/hqdefault.jpg Did you know that having excessive degraded NAD is bad for health? If you are taking NMN or NR, you must know the most important tricks to make it work for you. Watch this video till the end to learn what you can do to maximise it's benefits. @wellnessbymiri #nmn #nad #nr #health #longevity #energy #antiaging #aging #metabolism #workout #mitochondria #ATP #exercise #muscle #vo2max #lifestyle #lifestylemedicine https://www.youtube-nocookie.com/embed/sP8b72Sr_jk 167 2025-03-14T14:06:44.000Z 2026-10-22T18:43:09.984Z https://longevityharbor.com/en/watch/sRbncoenYpg Video description on lifestyle, ageing hallmarks and five anti-ageing topics https://i.ytimg.com/vi/sRbncoenYpg/hqdefault.jpg The description says 75–95% of lifespan is due to lifestyle and luck, claims ageing hallmarks could be slowed, and lists five topics: strength and muscle, metabolic flexibility and nutrition, movement quality and mobility, recovery, and hormone optimisation through lifestyle. https://www.youtube-nocookie.com/embed/sRbncoenYpg 638 2026-05-06T15:01:28.000Z 2026-10-23T01:07:43.524Z https://longevityharbor.com/de/watch/sRbncoenYpg Videobeschreibung zu Lebensstil, Alternsmerkmalen und fünf Anti-Aging-Themen https://i.ytimg.com/vi/sRbncoenYpg/hqdefault.jpg Laut Beschreibung sind 75–95 % der Lebensspanne auf Lebensstil und Glück zurückzuführen; Alternsmerkmale könnten verlangsamt werden. Genannt werden fünf Themen: Kraft und Muskelerhalt, metabolische Flexibilität und Ernährung, Bewegungsqualität und Mobilität, Erholung sowie Hormonoptimierung durch Lebensstil. https://www.youtube-nocookie.com/embed/sRbncoenYpg 638 2026-05-06T15:01:28.000Z 2026-10-23T01:07:43.524Z https://longevityharbor.com/en/watch/sUC-QX6wDeI Video description: timing tips for astaxanthin and NMN supplements https://i.ytimg.com/vi/sUC-QX6wDeI/hqdefault.jpg The description says astaxanthin and NMN may work better together and gives timing tips, such as taking them in the morning and not past 2pm if sleep is a problem. It calls this general education, not personalized medical advice. https://www.youtube-nocookie.com/embed/sUC-QX6wDeI 121 2026-10-04T15:43:04.000Z 2026-10-22T21:25:24.471Z https://longevityharbor.com/de/watch/sUC-QX6wDeI Videobeschreibung: Einnahmehinweise zu Astaxanthin und NMN https://i.ytimg.com/vi/sUC-QX6wDeI/hqdefault.jpg Die Beschreibung sagt, Astaxanthin und NMN könnten zusammen besser wirken, und gibt Einnahmehinweise, etwa morgens und nicht nach 14 Uhr bei Schlafproblemen. Sie nennt dies allgemeine Bildung, keine persönliche medizinische Beratung. https://www.youtube-nocookie.com/embed/sUC-QX6wDeI 121 2026-10-04T15:43:04.000Z 2026-10-22T21:25:24.471Z https://longevityharbor.com/en/watch/sVYCO_apXMg Ana Maria Cuervo discusses cellular recycling, autophagy and aging in a video description https://i.ytimg.com/vi/sVYCO_apXMg/hqdefault.jpg According to the description, host Eric Verdin talks with Dr. Ana Maria Cuervo about proteostasis, autophagy and her discovery of chaperone-mediated autophagy, and about how sleep, exercise and meal timing may influence these pathways. The description makes no study results or human lifespan claims. https://www.youtube-nocookie.com/embed/sVYCO_apXMg 2804 2026-03-04T13:25:44.000Z 2026-10-23T02:17:23.926Z https://longevityharbor.com/de/watch/sVYCO_apXMg Ana Maria Cuervo über zelluläres Recycling, Autophagie und Altern in einer Videobeschreibung https://i.ytimg.com/vi/sVYCO_apXMg/hqdefault.jpg Laut Beschreibung spricht Gastgeber Eric Verdin mit Dr. Ana Maria Cuervo über Proteostase, Autophagie und ihre Entdeckung der chaperonvermittelten Autophagie sowie darüber, wie Schlaf, Bewegung und Essenszeit diese Wege beeinflussen könnten. Die Beschreibung nennt keine Studienergebnisse oder Aussagen zur menschlichen Lebensspanne. https://www.youtube-nocookie.com/embed/sVYCO_apXMg 2804 2026-03-04T13:25:44.000Z 2026-10-23T02:17:23.926Z https://longevityharbor.com/en/watch/sca847faTug Rapamycin in aging biology: mouse lifespan data, not human longevity proof https://i.ytimg.com/vi/sca847faTug/hqdefault.jpg The description says rapamycin is not a proven human longevity therapy, yet mTOR inhibition has repeatedly extended lifespan in laboratory animals, including mice. https://www.youtube-nocookie.com/embed/sca847faTug 140 2026-08-13T23:35:07.000Z 2026-10-22T23:01:56.470Z https://longevityharbor.com/de/watch/sca847faTug Rapamycin in der Alternsbiologie: Maus-Lebensspandaten, kein Human-Langlebigkeitsbeweis https://i.ytimg.com/vi/sca847faTug/hqdefault.jpg Laut Beschreibung ist Rapamycin keine bewiesene Langlebigkeitstherapie für Menschen, doch mTOR-Hemmung verlängerte im Labor wiederholt die Lebensspanne, auch bei Mäusen. https://www.youtube-nocookie.com/embed/sca847faTug 140 2026-08-13T23:35:07.000Z 2026-10-22T23:01:56.470Z https://longevityharbor.com/en/watch/sdDPhh0wkjM 70: Rapamycin and Longevity: What the Research Really Says with Dr. Ben Bikman https://i.ytimg.com/vi/sdDPhh0wkjM/hqdefault.jpg 📢 Ask Dr. Bikman’s Digital Mind: https://benbikman.com/ben-bikmans-digital-ai-mind In today’s episode of The Metabolic Classroom, Dr. Ben Bikman delivers a lecture focusing on the drug rapamycin and its impact on longevity. The primary discussion revolves around the role of the protein complex mTOR (mammalian target of rapamycin) in the body's aging process. While rapamycin is often touted as a drug that can inhibit mTOR and thereby promote longevity, Ben emphasizes that much of this belief is based on animal studies and lacks solid human evidence. The mTOR pathway is involved in cell growth and protein synthesis, particularly in muscle tissue, making its inhibition controversial when it comes to aging and muscle maintenance. Dr. Bikman highlights that some research suggests reducing mTOR activity by lowering protein intake might promote longevity. However, he pointed out that for older populations, higher protein consumption is correlated with reduced mortality, particularly from animal protein sources. This is especially significant when considering muscle mass, which has been consistently linked to longer lifespan. Inhibiting mTOR might impair muscle growth and maintenance, making rapamycin problematic for those aiming to preserve muscle health as they age. In addition to discussing the potential benefits of rapamycin, Ben underscores its negative side effects, including immune suppression, increased triglycerides (which elevate the risk of heart disease), and the inhibition of muscle protein synthesis. He also raises concerns about the drug’s ability to reduce testosterone levels and hinder reproductive health in both men and women. Given that reproduction is a key element of both evolutionary theory and many religious doctrines, Dr. Bikman questions the wisdom of using a drug that compromises reproductive function. Dr. Bikman concludes by connecting the role of insulin to mTOR activation. He argues that insulin has a much stronger effect on mTOR than dietary protein does, and prolonged elevated insulin https://www.youtube-nocookie.com/embed/sdDPhh0wkjM 1902 2024-09-12T13:24:19.000Z 2026-10-22T17:43:41.057Z https://longevityharbor.com/de/watch/sdDPhh0wkjM 70: Rapamycin and Longevity: What the Research Really Says with Dr. Ben Bikman https://i.ytimg.com/vi/sdDPhh0wkjM/hqdefault.jpg 📢 Ask Dr. Bikman’s Digital Mind: https://benbikman.com/ben-bikmans-digital-ai-mind In today’s episode of The Metabolic Classroom, Dr. Ben Bikman delivers a lecture focusing on the drug rapamycin and its impact on longevity. The primary discussion revolves around the role of the protein complex mTOR (mammalian target of rapamycin) in the body's aging process. While rapamycin is often touted as a drug that can inhibit mTOR and thereby promote longevity, Ben emphasizes that much of this belief is based on animal studies and lacks solid human evidence. The mTOR pathway is involved in cell growth and protein synthesis, particularly in muscle tissue, making its inhibition controversial when it comes to aging and muscle maintenance. Dr. Bikman highlights that some research suggests reducing mTOR activity by lowering protein intake might promote longevity. However, he pointed out that for older populations, higher protein consumption is correlated with reduced mortality, particularly from animal protein sources. This is especially significant when considering muscle mass, which has been consistently linked to longer lifespan. Inhibiting mTOR might impair muscle growth and maintenance, making rapamycin problematic for those aiming to preserve muscle health as they age. In addition to discussing the potential benefits of rapamycin, Ben underscores its negative side effects, including immune suppression, increased triglycerides (which elevate the risk of heart disease), and the inhibition of muscle protein synthesis. He also raises concerns about the drug’s ability to reduce testosterone levels and hinder reproductive health in both men and women. Given that reproduction is a key element of both evolutionary theory and many religious doctrines, Dr. Bikman questions the wisdom of using a drug that compromises reproductive function. Dr. Bikman concludes by connecting the role of insulin to mTOR activation. He argues that insulin has a much stronger effect on mTOR than dietary protein does, and prolonged elevated insulin https://www.youtube-nocookie.com/embed/sdDPhh0wkjM 1902 2024-09-12T13:24:19.000Z 2026-10-22T17:43:41.057Z https://longevityharbor.com/en/watch/sdfZIBph3n4 Valter Longo at ARDD2023: Fasting Mimicking Diets, Multi-system regeneration and Longevity https://i.ytimg.com/vi/sdfZIBph3n4/hqdefault.jpg Valter Longo, USC Davis School of Gerontology, USA presents at the 10th Aging Research and Drug Discovery conference: Fasting Mimicking Diets, Multi-system regeneration and Longevity https://www.youtube-nocookie.com/embed/sdfZIBph3n4 1305 2023-11-22T11:13:08.000Z 2026-10-22T19:32:31.863Z https://longevityharbor.com/de/watch/sdfZIBph3n4 Valter Longo at ARDD2023: Fasting Mimicking Diets, Multi-system regeneration and Longevity https://i.ytimg.com/vi/sdfZIBph3n4/hqdefault.jpg Valter Longo, USC Davis School of Gerontology, USA presents at the 10th Aging Research and Drug Discovery conference: Fasting Mimicking Diets, Multi-system regeneration and Longevity https://www.youtube-nocookie.com/embed/sdfZIBph3n4 1305 2023-11-22T11:13:08.000Z 2026-10-22T19:32:31.863Z https://longevityharbor.com/en/watch/senntZLg8UM Video description claims melatonin rules for cellular youth and longevity https://i.ytimg.com/vi/senntZLg8UM/hqdefault.jpg The description presents melatonin as more than a sleep aid and lists ten rules it says support cellular youth, including micro-dosing, blocking blue light, timing and gut health. These are creator claims from the description only. https://www.youtube-nocookie.com/embed/senntZLg8UM 116 2026-07-19T18:50:12.000Z 2026-10-22T23:29:34.895Z https://longevityharbor.com/de/watch/senntZLg8UM Videobeschreibung behauptet Melatonin-Regeln für Zelljugend und Langlebigkeit https://i.ytimg.com/vi/senntZLg8UM/hqdefault.jpg Die Beschreibung stellt Melatonin als mehr als ein Schlafmittel dar und nennt zehn Regeln, die angeblich die Zelljugend fördern, darunter Mikrodosierung, Blaulichtblockade, Timing und Darmgesundheit. Dies sind Aussagen des Erstellers aus der Beschreibung. https://www.youtube-nocookie.com/embed/senntZLg8UM 116 2026-07-19T18:50:12.000Z 2026-10-22T23:29:34.895Z https://longevityharbor.com/en/watch/sfRN-nb9RrQ Damage vs Repair: The Hallmarks of Aging Explained- with Red O'Laughlin on The Corner Bookstore https://i.ytimg.com/vi/sfRN-nb9RrQ/hqdefault.jpg Damage vs Repair: The Hallmarks of Aging Explained- with Red O'Laughlin on The Corner Bookstore https://www.youtube-nocookie.com/embed/sfRN-nb9RrQ 100 2026-06-06T23:37:37.000Z 2026-10-22T19:04:37.378Z https://longevityharbor.com/de/watch/sfRN-nb9RrQ Damage vs Repair: The Hallmarks of Aging Explained- with Red O'Laughlin on The Corner Bookstore https://i.ytimg.com/vi/sfRN-nb9RrQ/hqdefault.jpg Damage vs Repair: The Hallmarks of Aging Explained- with Red O'Laughlin on The Corner Bookstore https://www.youtube-nocookie.com/embed/sfRN-nb9RrQ 100 2026-06-06T23:37:37.000Z 2026-10-22T19:04:37.378Z https://longevityharbor.com/en/watch/sgY6kYzZ1bM 👉 ProLon Day 5: Final Results & Full Body Reset (Was It Worth It?) https://i.ytimg.com/vi/sgY6kYzZ1bM/hqdefault.jpg Prolon DAY 5 — Cellular Reset (FINAL DAY) ✨ Today marks the completion of my 5-day fasting mimicking journey—and what a transformation it has been. My body has entered a powerful state of deep renewal and repair. Through autophagy, old and damaged cells are cleared, making way for newer, healthier, high-functioning cells. This is what true healing looks like from the inside out: ✔️ Cellular cleanup ✔️ Fat burning at its peak ✔️ Reduced inflammation ✔️ Metabolic reset ✔️ Renewed energy and clarity ✔️Slimmer waistline And the best part? This wasn’t starvation or extreme restriction. This was a science-backed, structured 5-day reboot—supported by over 25+ years of clinical research. Instead of: ❌ Unsustainable water fasts ❌ Chronic low-calorie dieting You can: ✅ Nourish your body ✅ Activate healing pathways ✅ Reset your metabolism safely I’m especially proud because this journey was intentional. I chose to release what no longer serves my body and embrace renewal at a cellular level. And you don’t have to do it alone. 💚 You’ll be guided 💚 You’ll be supported 💚 You’ll have a community walking with you every step of the way If you’ve been thinking about a reset—this is your sign. 👉🏾 Want to learn more? Send me a message 👉🏾 Ready to start? Use the link in the comments for my discount We all deserve to live at our finest well-being—body, mind, and spirit. #ProLon #FastingMimickingDiet #MetabolicHealth #Autophagy #InflammationReduction #CellularHealth #Longevity https://www.youtube-nocookie.com/embed/sgY6kYzZ1bM 177 2026-04-03T17:25:37.000Z 2026-10-22T19:32:32.291Z https://longevityharbor.com/de/watch/sgY6kYzZ1bM 👉 ProLon Day 5: Final Results & Full Body Reset (Was It Worth It?) https://i.ytimg.com/vi/sgY6kYzZ1bM/hqdefault.jpg Prolon DAY 5 — Cellular Reset (FINAL DAY) ✨ Today marks the completion of my 5-day fasting mimicking journey—and what a transformation it has been. My body has entered a powerful state of deep renewal and repair. Through autophagy, old and damaged cells are cleared, making way for newer, healthier, high-functioning cells. This is what true healing looks like from the inside out: ✔️ Cellular cleanup ✔️ Fat burning at its peak ✔️ Reduced inflammation ✔️ Metabolic reset ✔️ Renewed energy and clarity ✔️Slimmer waistline And the best part? This wasn’t starvation or extreme restriction. This was a science-backed, structured 5-day reboot—supported by over 25+ years of clinical research. Instead of: ❌ Unsustainable water fasts ❌ Chronic low-calorie dieting You can: ✅ Nourish your body ✅ Activate healing pathways ✅ Reset your metabolism safely I’m especially proud because this journey was intentional. I chose to release what no longer serves my body and embrace renewal at a cellular level. And you don’t have to do it alone. 💚 You’ll be guided 💚 You’ll be supported 💚 You’ll have a community walking with you every step of the way If you’ve been thinking about a reset—this is your sign. 👉🏾 Want to learn more? Send me a message 👉🏾 Ready to start? Use the link in the comments for my discount We all deserve to live at our finest well-being—body, mind, and spirit. #ProLon #FastingMimickingDiet #MetabolicHealth #Autophagy #InflammationReduction #CellularHealth #Longevity https://www.youtube-nocookie.com/embed/sgY6kYzZ1bM 177 2026-04-03T17:25:37.000Z 2026-10-22T19:32:32.291Z https://longevityharbor.com/en/watch/shZcCl0QUj8 Video description on low-carb, keto and healthy eating for men over 45 https://i.ytimg.com/vi/shZcCl0QUj8/hqdefault.jpg The description says the video examines whether rapid low-carb or keto weight loss can stress the body and affect cell aging in men over 40, and presents strategies for healthy aging. https://www.youtube-nocookie.com/embed/shZcCl0QUj8 633 2026-07-05T08:15:02.000Z 2026-10-22T23:39:50.468Z https://longevityharbor.com/de/watch/shZcCl0QUj8 Videobeschreibung zu Low-Carb, Keto und gesunder Ernährung für Männer ab 45 https://i.ytimg.com/vi/shZcCl0QUj8/hqdefault.jpg Laut Beschreibung untersucht das Video, ob schneller Gewichtsverlust mit Low-Carb oder Keto den Körper stressen und die Zellalterung bei Männern ab 40 beeinflussen kann, und stellt Strategien für gesundes Altern vor. https://www.youtube-nocookie.com/embed/shZcCl0QUj8 633 2026-07-05T08:15:02.000Z 2026-10-22T23:39:50.468Z https://longevityharbor.com/en/watch/sil8stVGPwA Matt Kaeberlein discusses rapamycin, biological clocks and longevity research https://i.ytimg.com/vi/sil8stVGPwA/hqdefault.jpg In this video description, Prof Matt Kaeberlein discusses mTOR biology, rapamycin, caloric restriction, biological clocks and limits of the hallmarks of aging framework; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/sil8stVGPwA 3466 2026-05-25T12:30:02.000Z 2026-10-23T00:26:07.311Z https://longevityharbor.com/de/watch/sil8stVGPwA Matt Kaeberlein über Rapamycin, biologische Uhren und Langlebigkeitsforschung https://i.ytimg.com/vi/sil8stVGPwA/hqdefault.jpg In dieser Videobeschreibung spricht Prof. Matt Kaeberlein über mTOR-Biologie, Rapamycin, Kalorienrestriktion, biologische Uhren und Grenzen des Hallmarks-of-Aging-Konzepts; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/sil8stVGPwA 3466 2026-05-25T12:30:02.000Z 2026-10-23T00:26:07.311Z https://longevityharbor.com/en/watch/sjxhScq7CoM The Added Insights of Proteomic Aging Clocks https://i.ytimg.com/vi/sjxhScq7CoM/hqdefault.jpg NotebookLM: "The sources discuss DamAge and Adaptage as part of a causality-enriched epigenetic framework in the video "Decoding the Ageome", while comparing the broader utility and performance of proteomic aging clocks vs. epigenetic clocks in the clinical trial literature. 1. Understanding DamAge and Adaptage Epigenetic Clocks: According to the video source, epigenetic markers of aging can be separated into two distinct, causality-enriched categories:DamAge: Tracks strictly deleterious, harmful alterations that accumulate on the genome as cells degrade1.Adaptage: Maps the protective adaptations the body intentionally mounts to defend itself in response to that degradation. While these causality-enriched models represent a major evolutionary step over first-generation epigenetic clocks—which failed in clinical trials because they only measured static, stochastic background noise—they are still constrained by the inherent physical and interpretive limitations of DNA methylation-based clocks. 2. Why Proteomic Aging Clocks Demonstrate Superior Characteristics: In contrast to epigenetic models, proteomic clocks offer several distinct advantages in trial performance, interpretability, and biological scope:Immediate Interpretability & Direct Mechanistic Insight: Epigenetic clocks rely on CpG methylation marks whose functional impacts on biological processes are highly indirect, providing limited mechanistic insight into the actual drivers of aging. Conversely, proteins are the immediate effectors of biological change. This allows proteomic clocks to yield immediately interpretable features, making predictions open to direct biological inspection. 3.Systemic vs. Lineage-Specific Signaling: DNA methylation profiles derived from blood samples primarily reflect the responses of human hematopoietic cell lineages to stimuli. On the other hand, circulating proteins in serum or plasma are better positioned to capture systemic physiological responses across different tissues and organ systems throughout the body. Consistency https://www.youtube-nocookie.com/embed/sjxhScq7CoM 552 2026-09-08T17:52:20.000Z 2026-10-22T18:32:06.754Z https://longevityharbor.com/de/watch/sjxhScq7CoM The Added Insights of Proteomic Aging Clocks https://i.ytimg.com/vi/sjxhScq7CoM/hqdefault.jpg NotebookLM: "The sources discuss DamAge and Adaptage as part of a causality-enriched epigenetic framework in the video "Decoding the Ageome", while comparing the broader utility and performance of proteomic aging clocks vs. epigenetic clocks in the clinical trial literature. 1. Understanding DamAge and Adaptage Epigenetic Clocks: According to the video source, epigenetic markers of aging can be separated into two distinct, causality-enriched categories:DamAge: Tracks strictly deleterious, harmful alterations that accumulate on the genome as cells degrade1.Adaptage: Maps the protective adaptations the body intentionally mounts to defend itself in response to that degradation. While these causality-enriched models represent a major evolutionary step over first-generation epigenetic clocks—which failed in clinical trials because they only measured static, stochastic background noise—they are still constrained by the inherent physical and interpretive limitations of DNA methylation-based clocks. 2. Why Proteomic Aging Clocks Demonstrate Superior Characteristics: In contrast to epigenetic models, proteomic clocks offer several distinct advantages in trial performance, interpretability, and biological scope:Immediate Interpretability & Direct Mechanistic Insight: Epigenetic clocks rely on CpG methylation marks whose functional impacts on biological processes are highly indirect, providing limited mechanistic insight into the actual drivers of aging. Conversely, proteins are the immediate effectors of biological change. This allows proteomic clocks to yield immediately interpretable features, making predictions open to direct biological inspection. 3.Systemic vs. Lineage-Specific Signaling: DNA methylation profiles derived from blood samples primarily reflect the responses of human hematopoietic cell lineages to stimuli. On the other hand, circulating proteins in serum or plasma are better positioned to capture systemic physiological responses across different tissues and organ systems throughout the body. Consistency https://www.youtube-nocookie.com/embed/sjxhScq7CoM 552 2026-09-08T17:52:20.000Z 2026-10-22T18:32:06.754Z https://longevityharbor.com/en/watch/slmuEY7eNUg My ultimate guide to senotherapeutics (senolytics vs. senomorphics) https://i.ytimg.com/vi/slmuEY7eNUg/hqdefault.jpg SPONSOR - Longevity.Technology : https://www.longevity.technology/?utm_source=LT&utm_medium=youtube&utm_campaign=senotherapeutics Senotherapeutics are therapeutics strategies that target cellular senescence. These strategies can work by killing senescent cells (senolytics), inhibiting the proinflammatory secretory phenotype of senescent cells (senomorphics) or by activating our endogenous senolytic systems (immune surveillance). But what even are senescent cells, how do senolytics work, and what current human clinical trials provide supporting data? In this video we will begin by discussing what senescent cells are, what causes a cell to become senescent and why targeting senescent cells may provide therapeutic potential for aging and age-related diseases. We will then look at the three main branches of senotherapeutics, senolytics vs. senomorphics and what future work is being conducted to evaluate the safety and efficacy of these strategies. So, in many ways you could consider this video my ultimate guide to senotherapeutics! :D TIMESTAMPS; Intro - 00:00 Senotherapeutics & senescent cells - 00:30 Senolytics - 04:20 Senomorphics - 08:00 Senolytics vs. senomorphics - 10:00 Immune surveillance - 11:55 REFERENCES; Di Micco, R., Krizhanovsky, V., Baker, D. et al. Cellular senescence in ageing: from mechanisms to therapeutic opportunities. Nat Rev Mol Cell Biol 22, 75–95 (2021). https://doi.org/10.1038/s41580-020-00314-w A versatile drug delivery system targeting senescent cells - https://doi.org/10.15252/emmm.201809355 Chan, A., & Narita, M. (2019). Short-term gain, long-term pain: the senescence life cycle and cancer. Genes & development, 33(3-4), 127–143. https://doi.org/10.1101/gad.320937.118 Check out @LongevityScienceNews latest video -- https://www.youtube.com/watch?v=WlmkCTHy7vM Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com https://www.youtube-nocookie.com/embed/slmuEY7eNUg 843 2021-05-07T14:00:12.000Z 2026-10-23T02:24:27.125Z https://longevityharbor.com/de/watch/slmuEY7eNUg My ultimate guide to senotherapeutics (senolytics vs. senomorphics) https://i.ytimg.com/vi/slmuEY7eNUg/hqdefault.jpg SPONSOR - Longevity.Technology : https://www.longevity.technology/?utm_source=LT&utm_medium=youtube&utm_campaign=senotherapeutics Senotherapeutics are therapeutics strategies that target cellular senescence. These strategies can work by killing senescent cells (senolytics), inhibiting the proinflammatory secretory phenotype of senescent cells (senomorphics) or by activating our endogenous senolytic systems (immune surveillance). But what even are senescent cells, how do senolytics work, and what current human clinical trials provide supporting data? In this video we will begin by discussing what senescent cells are, what causes a cell to become senescent and why targeting senescent cells may provide therapeutic potential for aging and age-related diseases. We will then look at the three main branches of senotherapeutics, senolytics vs. senomorphics and what future work is being conducted to evaluate the safety and efficacy of these strategies. So, in many ways you could consider this video my ultimate guide to senotherapeutics! :D TIMESTAMPS; Intro - 00:00 Senotherapeutics & senescent cells - 00:30 Senolytics - 04:20 Senomorphics - 08:00 Senolytics vs. senomorphics - 10:00 Immune surveillance - 11:55 REFERENCES; Di Micco, R., Krizhanovsky, V., Baker, D. et al. Cellular senescence in ageing: from mechanisms to therapeutic opportunities. Nat Rev Mol Cell Biol 22, 75–95 (2021). https://doi.org/10.1038/s41580-020-00314-w A versatile drug delivery system targeting senescent cells - https://doi.org/10.15252/emmm.201809355 Chan, A., & Narita, M. (2019). Short-term gain, long-term pain: the senescence life cycle and cancer. Genes & development, 33(3-4), 127–143. https://doi.org/10.1101/gad.320937.118 Check out @LongevityScienceNews latest video -- https://www.youtube.com/watch?v=WlmkCTHy7vM Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com https://www.youtube-nocookie.com/embed/slmuEY7eNUg 843 2021-05-07T14:00:12.000Z 2026-10-23T02:24:27.125Z https://longevityharbor.com/en/watch/sraCMDpDtgI Understanding aging and ADRD disparities using a representative epigenetic clock https://i.ytimg.com/vi/sraCMDpDtgI/hqdefault.jpg Disadvantaged groups may experience accelerated biological aging, due to the cumulative impact of repeated experiences with socioeconomic adversity and marginalization. This may cause early physical and cognitive health deterioration leading to disparities in aging and Alzheimer's disease and related dementias (ADRD) outcomes, as evident in associations of epigenetic clocks with worse aging and ADRD outcomes. Epigenetic clocks apply machine learning to DNA methylation profiles from blood samples to estimate biological aging. Black American adults show accelerated epigenetic aging compared to White American adults and socioeconomic factors contribute to this racial disparity. However, epigenetic clocks have been developed using non-representative datasets consisting predominantly of White adults and therefore may not provide accurate estimates of epigenetic aging in other racial and ethnic groups. We will use machine learning to develop and validate a representative epigenetic clock (REpiClock) to more accurately predict epigenetic age in Black adults. As the accuracy of epigenetic age estimates may be influenced by the genetic distance of a target individual from the average genotype of the training dataset, we will apply a data-driven method to correct epigenetic age predictions for the individual’s genetic distance from the training set. In a deeply-phenotyped biobank, we will assess the relationship of the REpiClock with ADRD pathology, using plasma biomarkers, and ADRD risk and aging outcomes, using electronic health record data. This will allow us to establish whether a representative, genetic distance-corrected epigenetic clock, more precisely estimates disparities in epigenetic aging and whether these disparities underlie disparities in ADRD pathology and risk. https://www.youtube-nocookie.com/embed/sraCMDpDtgI 508 2025-07-01T03:46:54.000Z 2026-10-22T17:43:35.311Z https://longevityharbor.com/de/watch/sraCMDpDtgI Understanding aging and ADRD disparities using a representative epigenetic clock https://i.ytimg.com/vi/sraCMDpDtgI/hqdefault.jpg Disadvantaged groups may experience accelerated biological aging, due to the cumulative impact of repeated experiences with socioeconomic adversity and marginalization. This may cause early physical and cognitive health deterioration leading to disparities in aging and Alzheimer's disease and related dementias (ADRD) outcomes, as evident in associations of epigenetic clocks with worse aging and ADRD outcomes. Epigenetic clocks apply machine learning to DNA methylation profiles from blood samples to estimate biological aging. Black American adults show accelerated epigenetic aging compared to White American adults and socioeconomic factors contribute to this racial disparity. However, epigenetic clocks have been developed using non-representative datasets consisting predominantly of White adults and therefore may not provide accurate estimates of epigenetic aging in other racial and ethnic groups. We will use machine learning to develop and validate a representative epigenetic clock (REpiClock) to more accurately predict epigenetic age in Black adults. As the accuracy of epigenetic age estimates may be influenced by the genetic distance of a target individual from the average genotype of the training dataset, we will apply a data-driven method to correct epigenetic age predictions for the individual’s genetic distance from the training set. In a deeply-phenotyped biobank, we will assess the relationship of the REpiClock with ADRD pathology, using plasma biomarkers, and ADRD risk and aging outcomes, using electronic health record data. This will allow us to establish whether a representative, genetic distance-corrected epigenetic clock, more precisely estimates disparities in epigenetic aging and whether these disparities underlie disparities in ADRD pathology and risk. https://www.youtube-nocookie.com/embed/sraCMDpDtgI 508 2025-07-01T03:46:54.000Z 2026-10-22T17:43:35.311Z https://longevityharbor.com/en/watch/srxj-7JUwiY Video description: three functional tests instead of commercial biological-age tests https://i.ytimg.com/vi/srxj-7JUwiY/hqdefault.jpg The description says many biological-age tests are scientifically interesting but often of little everyday use, and presents stair climbing, sit-and-rise and grip strength as simple functional checks of physical reserves. https://www.youtube-nocookie.com/embed/srxj-7JUwiY 640 2026-07-05T08:00:23.000Z 2026-10-22T23:39:59.440Z https://longevityharbor.com/de/watch/srxj-7JUwiY Videobeschreibung: drei Funktionstests statt kommerzieller Tests zum biologischen Alter https://i.ytimg.com/vi/srxj-7JUwiY/hqdefault.jpg Die Beschreibung sagt, viele Tests zum biologischen Alter seien wissenschaftlich interessant, für den Alltag aber oft wenig aussagekräftig, und stellt Treppensteigen, Sit-and-Rise und Griffkraft als einfache Funktionsprüfungen körperlicher Reserven vor. https://www.youtube-nocookie.com/embed/srxj-7JUwiY 640 2026-07-05T08:00:23.000Z 2026-10-22T23:39:59.440Z https://longevityharbor.com/en/watch/sudyqPvJI5c Video description: zombie cells, inflammation and senolytics research https://i.ytimg.com/vi/sudyqPvJI5c/hqdefault.jpg The description says some cells do not die when they should and release inflammation signals into their surroundings; it calls this one of the best-supported drivers of aging and announces sections on triggers, the SASP cocktail and senolytics research. https://www.youtube-nocookie.com/embed/sudyqPvJI5c 410 2026-07-24T21:29:10.000Z 2026-10-22T23:22:46.591Z https://longevityharbor.com/de/watch/sudyqPvJI5c Videobeschreibung: Zombie-Zellen, Entzündung und Senolytika-Forschung https://i.ytimg.com/vi/sudyqPvJI5c/hqdefault.jpg Laut Beschreibung sterben manche Zellen nicht, wenn sie sollten, und geben Entzündungssignale an ihre Nachbarschaft ab; dies nennt sie einen der am besten belegten Treiber des Alterns und kündigt Abschnitte zu Auslösern, dem SASP-Cocktail und der Senolytika-Forschung an. https://www.youtube-nocookie.com/embed/sudyqPvJI5c 410 2026-07-24T21:29:10.000Z 2026-10-22T23:22:46.591Z https://longevityharbor.com/en/watch/svAMgR6LBZA Podcast description: centenarians, aging therapies and longevity biotech investing https://i.ytimg.com/vi/svAMgR6LBZA/hqdefault.jpg The description says the discussion covers lessons from centenarians, emerging therapies targeting aging, epigenetic reprogramming and investment opportunities in longevity biotech. https://www.youtube-nocookie.com/embed/svAMgR6LBZA 3637 2026-09-28T19:43:45.000Z 2026-10-22T21:39:20.114Z https://longevityharbor.com/de/watch/svAMgR6LBZA Podcast-Beschreibung: Hundertjährige, Alterungstherapien und Investitionen in Langlebigkeits-Biotech https://i.ytimg.com/vi/svAMgR6LBZA/hqdefault.jpg Laut Beschreibung behandelt die Diskussion Lehren von Hundertjährigen, neue Therapien gegen Alterung, epigenetische Reprogrammierung und Investitionsmöglichkeiten in Langlebigkeits-Biotech. https://www.youtube-nocookie.com/embed/svAMgR6LBZA 3637 2026-09-28T19:43:45.000Z 2026-10-22T21:39:20.114Z https://longevityharbor.com/en/watch/sx-6TIul_dQ Video description: ancient exercises and healthy aging claims https://i.ytimg.com/vi/sx-6TIul_dQ/hqdefault.jpg The description presents a video about ancient movement patterns such as the resting squat, dead hang, balance training and slow breathing, said to support joints, the nervous system and longevity. It lists research areas but reports no results. https://www.youtube-nocookie.com/embed/sx-6TIul_dQ 1289 2026-08-18T16:00:11.000Z 2026-10-22T22:56:36.324Z https://longevityharbor.com/de/watch/sx-6TIul_dQ Videobeschreibung: alte Übungen und Aussagen zum gesunden Altern https://i.ytimg.com/vi/sx-6TIul_dQ/hqdefault.jpg Die Beschreibung stellt ein Video über alte Bewegungsmuster wie Hocke, Hängen, Gleichgewichtstraining und langsames Atmen vor, die Gelenke, Nervensystem und Langlebigkeit unterstützen sollen. Sie nennt Forschungsbereiche, aber keine Ergebnisse. https://www.youtube-nocookie.com/embed/sx-6TIul_dQ 1289 2026-08-18T16:00:11.000Z 2026-10-22T22:56:36.324Z https://longevityharbor.com/en/watch/syRX4SvB5g4 Video description on 12–16-hour fasting, sirtuins and telomeres https://i.ytimg.com/vi/syRX4SvB5g4/hqdefault.jpg The description says the video explains metabolic changes during eating pauses and examines sirtuins, telomeres and calorie restriction, while stating that fasting is not proven to stop ageing or reliably extend human life. https://www.youtube-nocookie.com/embed/syRX4SvB5g4 2458 2026-09-23T16:30:10.000Z 2026-10-22T21:55:58.252Z https://longevityharbor.com/de/watch/syRX4SvB5g4 Videobeschreibung zu 12–16 Stunden Fasten, Sirtuinen und Telomeren https://i.ytimg.com/vi/syRX4SvB5g4/hqdefault.jpg Laut Beschreibung erklärt das Video Stoffwechselveränderungen in Essenspausen und beleuchtet Sirtuine, Telomere und Kalorienrestriktion; zugleich wird betont, dass Fasten den Alterungsprozess nicht nachweislich aufhält oder das menschliche Leben zuverlässig verlängert. https://www.youtube-nocookie.com/embed/syRX4SvB5g4 2458 2026-09-23T16:30:10.000Z 2026-10-22T21:55:58.252Z https://longevityharbor.com/en/watch/syjslWfDtt0 Mayo Clinic maps senescent cells, reversing age-related memory loss in mice #Senolytics #MayoClinic https://i.ytimg.com/vi/syjslWfDtt0/hqdefault.jpg Mayo Clinic's DNA aptamers can now locate senescent cells in human tissue - and a separate team reversed memory deficits in aged mice by blocking immune cells from crossing into the brain. Together, these findings shift aging biology from a measurement problem into a design problem. The aptamers give senolytics its first reliable readout: dosing protocols become biological rather than symptomatic, and the next generation of therapies can be designed against a live signal rather than guesswork. The immune-system pathway the T-cell research opens draws on antibody classes already deployed in other conditions, compressing the distance between mechanism and clinical candidate. The picture forming across both findings is a multi-system failure with multiple addressable levers. The instruments being built this year are the ones the next generation of treatments will be calibrated against. Subscribe to The Century Report for daily coverage of the science reshaping the long arc. Watch the full episode here: https://www.youtube.com/watch?v=nn66zzmnetg Get the full story on all of this and much more - read the full edition of today's Century Report here: https://sharedsapience.com/the-century-report-may-15-2026/ #MayoClinic #Dual #Mayo #Full #Biotech #CleanEnergy #TechNews https://www.youtube-nocookie.com/embed/syjslWfDtt0 119 2026-05-16T00:39:49.000Z 2026-10-22T19:21:23.268Z https://longevityharbor.com/de/watch/syjslWfDtt0 Mayo Clinic maps senescent cells, reversing age-related memory loss in mice #Senolytics #MayoClinic https://i.ytimg.com/vi/syjslWfDtt0/hqdefault.jpg Mayo Clinic's DNA aptamers can now locate senescent cells in human tissue - and a separate team reversed memory deficits in aged mice by blocking immune cells from crossing into the brain. Together, these findings shift aging biology from a measurement problem into a design problem. The aptamers give senolytics its first reliable readout: dosing protocols become biological rather than symptomatic, and the next generation of therapies can be designed against a live signal rather than guesswork. The immune-system pathway the T-cell research opens draws on antibody classes already deployed in other conditions, compressing the distance between mechanism and clinical candidate. The picture forming across both findings is a multi-system failure with multiple addressable levers. The instruments being built this year are the ones the next generation of treatments will be calibrated against. Subscribe to The Century Report for daily coverage of the science reshaping the long arc. Watch the full episode here: https://www.youtube.com/watch?v=nn66zzmnetg Get the full story on all of this and much more - read the full edition of today's Century Report here: https://sharedsapience.com/the-century-report-may-15-2026/ #MayoClinic #Dual #Mayo #Full #Biotech #CleanEnergy #TechNews https://www.youtube-nocookie.com/embed/syjslWfDtt0 119 2026-05-16T00:39:49.000Z 2026-10-22T19:21:23.268Z https://longevityharbor.com/en/watch/t0g5Ve4_-Zo Epigenetic clocks: what the test measures and what it cannot tell you https://i.ytimg.com/vi/t0g5Ve4_-Zo/hqdefault.jpg The podcast description says epigenetic clocks were built for groups, while a test kit measures one person; it also questions how the TRIIM study is read and flags a clock sold with its own supplement. https://www.youtube-nocookie.com/embed/t0g5Ve4_-Zo 627 2026-09-25T14:26:12.000Z 2026-10-22T21:49:03.292Z https://longevityharbor.com/de/watch/t0g5Ve4_-Zo Epigenetische Uhren: Was der Test misst und was er nicht sagen kann https://i.ytimg.com/vi/t0g5Ve4_-Zo/hqdefault.jpg Die Podcast-Beschreibung sagt, epigenetische Uhren seien für Gruppen gebaut, ein Testkit messe aber eine Person; sie hinterfragt auch die Lesart der TRIIM-Studie und nennt eine mit eigenem Supplement verkaufte Uhr ein Warnsignal. https://www.youtube-nocookie.com/embed/t0g5Ve4_-Zo 627 2026-09-25T14:26:12.000Z 2026-10-22T21:49:03.292Z https://longevityharbor.com/en/watch/t0z4MULDr1A Mouse study: senolytic 753b slowed disc aging in males, not females https://i.ytimg.com/vi/t0z4MULDr1A/hqdefault.jpg In aging mice, long-term systemic 753b reduced signs of intervertebral disc degeneration in 22-month-old males but not females, per the description. https://www.youtube-nocookie.com/embed/t0z4MULDr1A 126 2026-07-27T15:15:54.000Z 2026-10-22T23:20:53.850Z https://longevityharbor.com/de/watch/t0z4MULDr1A Mausstudie: Senolytikum 753b verlangsamte Bandscheibenalterung bei Männchen, nicht bei Weibchen https://i.ytimg.com/vi/t0z4MULDr1A/hqdefault.jpg Bei alternden Mäusen verringerte langfristiges systemisches 753b laut Beschreibung Anzeichen der Bandscheibendegeneration bei 22 Monate alten Männchen, nicht bei Weibchen. https://www.youtube-nocookie.com/embed/t0z4MULDr1A 126 2026-07-27T15:15:54.000Z 2026-10-22T23:20:53.850Z https://longevityharbor.com/en/watch/t2VoYw3iHN0 3 Simple Steps to Hack Autophagy Every Night (The Power of Sleep) https://i.ytimg.com/vi/t2VoYw3iHN0/hqdefault.jpg The Ultimate "Cellular Reset": Sleep, Autophagy, and the Anti-Aging Secret [Start with a strong hook & question] You know that feeling of waking up completely refreshed? It's not luck—it's your body's most powerful healing mechanism at work! In this video, we dive deep into the science of Autophagy (the body's internal "self-eating" process) and reveal how your daily sleep routine is the most overlooked and most effective trigger for this cellular cleanup. Forget expensive supplements; your best anti-aging hack is already wired into your biology. [Summary of Key Learnings - Use high-value keywords] Autophagy means "self-eating," and it’s how your cells recycle damaged organelles, wonky proteins, and cellular junk. This essential cellular repair process is crucial for slowing aging, reducing inflammation, and protecting against neurodegenerative diseases like Alzheimer's. We explain the powerful connection between deep sleep, circadian rhythm, and Autophagy activation. Learn exactly when your body cleans house and how disrupting your sleep schedule stops this vital repair cycle, leaving cellular "trash" to accumulate. In this video, you will learn: What Autophagy is and why it's your body's ultimate defense system. Why sleep is an equally powerful Autophagy trigger as fasting. How poor sleep directly contributes to cellular stress and disease risk. Simple, actionable steps to align your circadian rhythm and activate your nightly cellular reset. https://www.youtube-nocookie.com/embed/t2VoYw3iHN0 181 2025-11-10T15:06:35.000Z 2026-10-22T19:21:24.430Z https://longevityharbor.com/de/watch/t2VoYw3iHN0 3 Simple Steps to Hack Autophagy Every Night (The Power of Sleep) https://i.ytimg.com/vi/t2VoYw3iHN0/hqdefault.jpg The Ultimate "Cellular Reset": Sleep, Autophagy, and the Anti-Aging Secret [Start with a strong hook & question] You know that feeling of waking up completely refreshed? It's not luck—it's your body's most powerful healing mechanism at work! In this video, we dive deep into the science of Autophagy (the body's internal "self-eating" process) and reveal how your daily sleep routine is the most overlooked and most effective trigger for this cellular cleanup. Forget expensive supplements; your best anti-aging hack is already wired into your biology. [Summary of Key Learnings - Use high-value keywords] Autophagy means "self-eating," and it’s how your cells recycle damaged organelles, wonky proteins, and cellular junk. This essential cellular repair process is crucial for slowing aging, reducing inflammation, and protecting against neurodegenerative diseases like Alzheimer's. We explain the powerful connection between deep sleep, circadian rhythm, and Autophagy activation. Learn exactly when your body cleans house and how disrupting your sleep schedule stops this vital repair cycle, leaving cellular "trash" to accumulate. In this video, you will learn: What Autophagy is and why it's your body's ultimate defense system. Why sleep is an equally powerful Autophagy trigger as fasting. How poor sleep directly contributes to cellular stress and disease risk. Simple, actionable steps to align your circadian rhythm and activate your nightly cellular reset. https://www.youtube-nocookie.com/embed/t2VoYw3iHN0 181 2025-11-10T15:06:35.000Z 2026-10-22T19:21:24.430Z https://longevityharbor.com/en/watch/t2xZR21b63c The 7 Deadliest Causes of Aging (And How Science Can Stop Them) | Ep. 359 https://i.ytimg.com/vi/t2xZR21b63c/hqdefault.jpg In this episode, I sit down with Dr. Aubrey de Grey, the biogerontologist who pioneered the damage-repair approach to aging, coined the concept of longevity escape velocity, and has spent over 25 years arguing that we don't need to fully understand aging to defeat it. Aubrey explains why the field is moving faster than ever but the money is flowing to the wrong places, with investors chasing low-hanging fruit while the most critical and neglected areas of damage repair remain badly underfunded. He breaks down his seven categories of age-related damage including cell loss, cell accumulation, mitochondrial mutations, intracellular waste, extracellular waste like amyloid, cancer-causing mutations, and loss of extracellular matrix elasticity, and explains why this classification has held up for over two decades while the hallmarks of aging have had to be revised from nine to twelve to fourteen. He walks through the results of his first combination mouse trial which stacked telomerase gene therapy, a senolytic, and heterochronic bone marrow transplant and showed additive lifespan extension but did not beat what calorie restriction alone could achieve. His next study stacks eight interventions including Yamanaka factors for epigenetic reprogramming, MSC-derived exosomes, a next-generation senolytic from a Spanish group that modified navitoclax to eliminate platelet toxicity, anti-IL-11 antibodies, CDC-42 inhibition, and more. The target is robust mouse rejuvenation, defined as doubling the remaining lifespan of middle-aged mice from 12 months to 24. He makes the case that achieving this result is the single domino that will cause the dozen most prominent longevity scientists to start making public timeframe predictions, which will mobilize influencers like Joe Rogan and Mr. Beast, which will mobilize the public, which will force governments to tear up regulatory barriers the same way they did for COVID vaccines. His phrase for this: making aging the new COVID. Join the other 20,000+ high-performers getti https://www.youtube-nocookie.com/embed/t2xZR21b63c 2806 2026-10-08T18:29:02.000Z 2026-10-22T19:54:19.383Z https://longevityharbor.com/de/watch/t2xZR21b63c The 7 Deadliest Causes of Aging (And How Science Can Stop Them) | Ep. 359 https://i.ytimg.com/vi/t2xZR21b63c/hqdefault.jpg In this episode, I sit down with Dr. Aubrey de Grey, the biogerontologist who pioneered the damage-repair approach to aging, coined the concept of longevity escape velocity, and has spent over 25 years arguing that we don't need to fully understand aging to defeat it. Aubrey explains why the field is moving faster than ever but the money is flowing to the wrong places, with investors chasing low-hanging fruit while the most critical and neglected areas of damage repair remain badly underfunded. He breaks down his seven categories of age-related damage including cell loss, cell accumulation, mitochondrial mutations, intracellular waste, extracellular waste like amyloid, cancer-causing mutations, and loss of extracellular matrix elasticity, and explains why this classification has held up for over two decades while the hallmarks of aging have had to be revised from nine to twelve to fourteen. He walks through the results of his first combination mouse trial which stacked telomerase gene therapy, a senolytic, and heterochronic bone marrow transplant and showed additive lifespan extension but did not beat what calorie restriction alone could achieve. His next study stacks eight interventions including Yamanaka factors for epigenetic reprogramming, MSC-derived exosomes, a next-generation senolytic from a Spanish group that modified navitoclax to eliminate platelet toxicity, anti-IL-11 antibodies, CDC-42 inhibition, and more. The target is robust mouse rejuvenation, defined as doubling the remaining lifespan of middle-aged mice from 12 months to 24. He makes the case that achieving this result is the single domino that will cause the dozen most prominent longevity scientists to start making public timeframe predictions, which will mobilize influencers like Joe Rogan and Mr. Beast, which will mobilize the public, which will force governments to tear up regulatory barriers the same way they did for COVID vaccines. His phrase for this: making aging the new COVID. Join the other 20,000+ high-performers getti https://www.youtube-nocookie.com/embed/t2xZR21b63c 2806 2026-10-08T18:29:02.000Z 2026-10-22T19:54:19.383Z https://longevityharbor.com/en/watch/t374XaXwvD8 Explaining mTOR and the biology behind rapamycin | Peter Attia & David Sabatini https://i.ytimg.com/vi/t374XaXwvD8/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/O67pvKxio10?si=iPjkfkor3el22ImO Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from The Drive, 272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more In this episode, Peter is joined by guests David Sabatini & Matt Kaeberlein, two world-leading experts on rapamycin & mTOR. In this clip, they discuss: - How mTOR works - The biology behind rapamycin - Lifespan and the aging process - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or dela https://www.youtube-nocookie.com/embed/t374XaXwvD8 627 2023-11-15T17:00:45.000Z 2026-10-22T17:43:41.049Z https://longevityharbor.com/de/watch/t374XaXwvD8 Explaining mTOR and the biology behind rapamycin | Peter Attia & David Sabatini https://i.ytimg.com/vi/t374XaXwvD8/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/O67pvKxio10?si=iPjkfkor3el22ImO Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from The Drive, 272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more In this episode, Peter is joined by guests David Sabatini & Matt Kaeberlein, two world-leading experts on rapamycin & mTOR. In this clip, they discuss: - How mTOR works - The biology behind rapamycin - Lifespan and the aging process - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or dela https://www.youtube-nocookie.com/embed/t374XaXwvD8 627 2023-11-15T17:00:45.000Z 2026-10-22T17:43:41.049Z https://longevityharbor.com/en/watch/t7VlhUUm2jM Video description: longer cell fats with age, sleep vs exercise, and lab-panel aging https://i.ytimg.com/vi/t7VlhUUm2jM/hqdefault.jpg A video description reports three studies: fats in cells shift to longer chains with age across species, with lifespan extension only in worms; in UK Biobank adults, swapping sleep for activity was tied to lower death risk only in people already sleeping enough; and uneven aging across five routine lab values predicted faster cognitive decline in older adults. https://www.youtube-nocookie.com/embed/t7VlhUUm2jM 270 2026-10-15T13:15:31.000Z 2026-10-22T19:52:37.396Z https://longevityharbor.com/de/watch/t7VlhUUm2jM Videobeschreibung: längere Zellfette im Alter, Schlaf vs. Bewegung und Laborwerte https://i.ytimg.com/vi/t7VlhUUm2jM/hqdefault.jpg Eine Videobeschreibung berichtet über drei Studien: Zellfette werden mit dem Alter länger, die Lebensspanne verlängerte sich nur bei Würmern; bei UK-Biobank-Erwachsenen war Schlaf gegen Bewegung zu tauschen nur bei ausreichend Schlafenden mit geringerem Sterberisiko verbunden; und ungleichmäßige Alterung bei fünf Routine-Laborwerten sagte bei Älteren einen schnelleren kognitiven Abbau voraus. https://www.youtube-nocookie.com/embed/t7VlhUUm2jM 270 2026-10-15T13:15:31.000Z 2026-10-22T19:52:37.396Z https://longevityharbor.com/en/watch/tJBLYAxpShw Video description: three simple exercises for staying mobile in old age https://i.ytimg.com/vi/tJBLYAxpShw/hqdefault.jpg According to the description, the creator presents three simple exercises to encourage older people to start moving, aiming to stay mobile and active and to avoid losing muscle mass; the description gives no measured results. https://www.youtube-nocookie.com/embed/tJBLYAxpShw 99 2026-03-15T15:39:33.000Z 2026-10-23T02:05:34.625Z https://longevityharbor.com/de/watch/tJBLYAxpShw Videobeschreibung: drei einfache Übungen für Beweglichkeit im Alter https://i.ytimg.com/vi/tJBLYAxpShw/hqdefault.jpg Laut Beschreibung zeigt die Erstellerin drei einfache Übungen, um ältere Menschen zum Anfangen zu ermutigen, mit dem Ziel, beweglich und aktiv zu bleiben und keine Muskelmasse zu verlieren; messbare Ergebnisse nennt die Beschreibung nicht. https://www.youtube-nocookie.com/embed/tJBLYAxpShw 99 2026-03-15T15:39:33.000Z 2026-10-23T02:05:34.625Z https://longevityharbor.com/en/watch/tK6z3yOxVOg Clearing Senescent Cells: The Next Frontier in Longevity Medicine https://i.ytimg.com/vi/tK6z3yOxVOg/hqdefault.jpg In this masterclass, Dr. Andrea Pryce discusses the exciting field of senolytics and their role in longevity science. She explains the mechanisms of aging, particularly focusing on senescent cells and their impact on health. The conversation covers the evidence from animal studies and human clinical trials, highlighting the effectiveness of senolytics in improving physical function and health span. Dr. Pryce explores natural senolytics, dosing protocols, and the future of anti-aging medicine, emphasizing the importance of actively managing senescent cells as part of a comprehensive health strategy. She also reviews the ProHealth Senolytic product portfolio and associated senolytic cleanse strategies. #senolytics #aging #longevity #senescentcells #healthspan #naturalcompounds #clinicaltrials #antiagingmedicine #healthbenefits #cellularhealth #prohealth #prohealthlongevity https://www.youtube-nocookie.com/embed/tK6z3yOxVOg 4038 2026-01-23T22:51:35.000Z 2026-10-22T19:43:47.678Z https://longevityharbor.com/de/watch/tK6z3yOxVOg Clearing Senescent Cells: The Next Frontier in Longevity Medicine https://i.ytimg.com/vi/tK6z3yOxVOg/hqdefault.jpg In this masterclass, Dr. Andrea Pryce discusses the exciting field of senolytics and their role in longevity science. She explains the mechanisms of aging, particularly focusing on senescent cells and their impact on health. The conversation covers the evidence from animal studies and human clinical trials, highlighting the effectiveness of senolytics in improving physical function and health span. Dr. Pryce explores natural senolytics, dosing protocols, and the future of anti-aging medicine, emphasizing the importance of actively managing senescent cells as part of a comprehensive health strategy. She also reviews the ProHealth Senolytic product portfolio and associated senolytic cleanse strategies. #senolytics #aging #longevity #senescentcells #healthspan #naturalcompounds #clinicaltrials #antiagingmedicine #healthbenefits #cellularhealth #prohealth #prohealthlongevity https://www.youtube-nocookie.com/embed/tK6z3yOxVOg 4038 2026-01-23T22:51:35.000Z 2026-10-22T19:43:47.678Z https://longevityharbor.com/en/watch/tO8fpK1GWQE From muscle in motion to exercise in ageing HD https://i.ytimg.com/vi/tO8fpK1GWQE/hqdefault.jpg This summer will see elite athletes in action in events such as the Commonwealth Games and the football World Cup. Improving performance at the highest levels is a serious multi-million industry where the scientific study of exercise can turn the movements of also-rans into the motions of winners. But understanding the fundamental biomechanics and physiology of the human body can benefit millions of people, not just sports stars, as they age. A major new BBSRC-funded study is now investigating the link between exercise tolerance and muscle metabolism. It's an area ripe for discovery and application, because the way we react to the stresses and strains of exercise is a strong predictor of mortality -- better as measured by some studies than factors such as having been a smoker, having high blood pressure, being obese or diabetic, or having high cholesterol. Read the full video feature at: http://bit.ly/Tt9dSN Please share and embed this video with credit to BBSRC. See BBSRC News for the latest news, features and events: http://www.bbsrc.ac.uk/news Follow BBSRC on Twitter: http://twitter.com/bbsrc https://www.youtube-nocookie.com/embed/tO8fpK1GWQE 268 2014-05-21T08:30:07.000Z 2026-10-22T17:43:36.892Z https://longevityharbor.com/de/watch/tO8fpK1GWQE From muscle in motion to exercise in ageing HD https://i.ytimg.com/vi/tO8fpK1GWQE/hqdefault.jpg This summer will see elite athletes in action in events such as the Commonwealth Games and the football World Cup. Improving performance at the highest levels is a serious multi-million industry where the scientific study of exercise can turn the movements of also-rans into the motions of winners. But understanding the fundamental biomechanics and physiology of the human body can benefit millions of people, not just sports stars, as they age. A major new BBSRC-funded study is now investigating the link between exercise tolerance and muscle metabolism. It's an area ripe for discovery and application, because the way we react to the stresses and strains of exercise is a strong predictor of mortality -- better as measured by some studies than factors such as having been a smoker, having high blood pressure, being obese or diabetic, or having high cholesterol. Read the full video feature at: http://bit.ly/Tt9dSN Please share and embed this video with credit to BBSRC. See BBSRC News for the latest news, features and events: http://www.bbsrc.ac.uk/news Follow BBSRC on Twitter: http://twitter.com/bbsrc https://www.youtube-nocookie.com/embed/tO8fpK1GWQE 268 2014-05-21T08:30:07.000Z 2026-10-22T17:43:36.892Z https://longevityharbor.com/en/watch/tPtKUMUarSU Exercise science scholar explains resistance training’s effects on aging muscles https://i.ytimg.com/vi/tPtKUMUarSU/hqdefault.jpg How does aging impact muscles, and how can people reduce the risk of muscle loss as they get older? Ashley Herda, assistant professor of exercise science at the University of Kansas, is investigating how resistance training can fight muscle loss in individuals as they age. Learn more about health, sport & exercise sciences at KU: hses.ku.edu https://www.youtube-nocookie.com/embed/tPtKUMUarSU 123 2023-02-06T19:42:58.000Z 2026-10-22T17:43:36.972Z https://longevityharbor.com/de/watch/tPtKUMUarSU Exercise science scholar explains resistance training’s effects on aging muscles https://i.ytimg.com/vi/tPtKUMUarSU/hqdefault.jpg How does aging impact muscles, and how can people reduce the risk of muscle loss as they get older? Ashley Herda, assistant professor of exercise science at the University of Kansas, is investigating how resistance training can fight muscle loss in individuals as they age. Learn more about health, sport & exercise sciences at KU: hses.ku.edu https://www.youtube-nocookie.com/embed/tPtKUMUarSU 123 2023-02-06T19:42:58.000Z 2026-10-22T17:43:36.972Z https://longevityharbor.com/en/watch/tTx6KuuQp20 How To Keep Your Immune System Young For Longer! https://i.ytimg.com/vi/tTx6KuuQp20/hqdefault.jpg How to reverse the ageing of the immune system. 👉 Gain FREE access to my exclusive 'Longevity Cheat Sheet'? Subscribe to my weekly newsletter https://www.lisatamati.com/lisa/ Shop our science backed longevity, Immune, gut and cellular health formulation "Rejuvenate Pro" by Aevum Labs. https://shop.lisatamati.com/pages/rejuvenate -------------------------------------------- ➡️ Are you ready to take control of your health & unlock the secrets to a longer, healthier & more vibrant life? https://www.lisatamati.com/healthspan-hacks-course/ Description: Immunosenescence: How Immune Aging Drives Whole-Body Decline 🧬 Your immune system doesn't just protect you—it regulates everything. As we age, immunosenescence quietly accelerates all 12 hallmarks of aging, from DNA damage to stem cell exhaustion. In this video, we explore the eye-opening research of Dr. David Furman and the 1000 Immunomes Project from The Buck Institute, revealing how immune decline is a root cause of chronic disease and aging. 🔍 We dive into: The loss of naïve immune cells and rise of exhausted memory cells Shrinking thymus gland = immune imbalance and chronic inflammation Cytokine storms, "inflammaging," and how this wears down your body How Rejuvenate Pro helps reverse the tide 🌿 What makes Rejuvenate Pro different? It’s scientifically formulated with Immunel®, a high-grade colostrum extract rich in Immune Defense Proteins from Quantec. These proteins help: Repair and seal the gut lining, addressing leaky gut Restore microbial balance, disrupted by toxins and inflammation Boost the immune system's regulatory capacity, improving barrier function By targeting gut-immune dysfunction, Rejuvenate Pro reduces chronic inflammation, supports detoxification, and revitalizes immune resilience from the inside out. 👉 Discover how to truly rejuvenate your immunity. 🔗 Learn more or shop Rejuvenate Pro https://shop.lisatamati.com/pages/rejuvenate www.aevumlabs.co.nz For all the research papers visit: https://aevumlabs.co.nz/pages/research https://www.youtube-nocookie.com/embed/tTx6KuuQp20 1533 2025-07-16T03:38:09.000Z 2026-10-22T19:32:33.364Z https://longevityharbor.com/de/watch/tTx6KuuQp20 How To Keep Your Immune System Young For Longer! https://i.ytimg.com/vi/tTx6KuuQp20/hqdefault.jpg How to reverse the ageing of the immune system. 👉 Gain FREE access to my exclusive 'Longevity Cheat Sheet'? Subscribe to my weekly newsletter https://www.lisatamati.com/lisa/ Shop our science backed longevity, Immune, gut and cellular health formulation "Rejuvenate Pro" by Aevum Labs. https://shop.lisatamati.com/pages/rejuvenate -------------------------------------------- ➡️ Are you ready to take control of your health & unlock the secrets to a longer, healthier & more vibrant life? https://www.lisatamati.com/healthspan-hacks-course/ Description: Immunosenescence: How Immune Aging Drives Whole-Body Decline 🧬 Your immune system doesn't just protect you—it regulates everything. As we age, immunosenescence quietly accelerates all 12 hallmarks of aging, from DNA damage to stem cell exhaustion. In this video, we explore the eye-opening research of Dr. David Furman and the 1000 Immunomes Project from The Buck Institute, revealing how immune decline is a root cause of chronic disease and aging. 🔍 We dive into: The loss of naïve immune cells and rise of exhausted memory cells Shrinking thymus gland = immune imbalance and chronic inflammation Cytokine storms, "inflammaging," and how this wears down your body How Rejuvenate Pro helps reverse the tide 🌿 What makes Rejuvenate Pro different? It’s scientifically formulated with Immunel®, a high-grade colostrum extract rich in Immune Defense Proteins from Quantec. These proteins help: Repair and seal the gut lining, addressing leaky gut Restore microbial balance, disrupted by toxins and inflammation Boost the immune system's regulatory capacity, improving barrier function By targeting gut-immune dysfunction, Rejuvenate Pro reduces chronic inflammation, supports detoxification, and revitalizes immune resilience from the inside out. 👉 Discover how to truly rejuvenate your immunity. 🔗 Learn more or shop Rejuvenate Pro https://shop.lisatamati.com/pages/rejuvenate www.aevumlabs.co.nz For all the research papers visit: https://aevumlabs.co.nz/pages/research https://www.youtube-nocookie.com/embed/tTx6KuuQp20 1533 2025-07-16T03:38:09.000Z 2026-10-22T19:32:33.364Z https://longevityharbor.com/en/watch/tX2hz-LqAio Gesunde Ernährung – Gesunde Zellen – Gesundes Altern https://i.ytimg.com/vi/tX2hz-LqAio/hqdefault.jpg Das Team am Institut für Altersforschung der LFUI beschäftigt sich mit biochemischen Prozessen in Zellen, die zu vorzeitigen Alterungsprozessen im menschlichen Körper führen. In diesem sehr weiten Wissenschaftsfeld liegt deren Fokus speziell auf den Alterungsprozessen, die durch Funktionsstörungen von sogenannten Mitochondrien ausgelöst werden. Ähnlich wie unser Körper aus diversen Organen besteht, finden sich in unseren Zellen sogenannte Organellen, die individuelle Aufgaben in der Zelle übernehmen. Mitochondrien sind solche Organellen, die für unsere Zellen chemische Energie herstellen. Wir wissen heute, dass viele Erkrankungen durch gestörte Mitochondrien Funktionen zumindest mitverursacht werden. Im Zuge der Forschung interessiert das Team speziell auf die Rolle von ausgewählten Proteinen in der möglichen Entstehung von mitochondrialer Dysfunktion und natürlich auch der Aspekt der möglichen Medikation im Alter, aber auch der Vorbeugung in jüngeren Jahren. Diverse Lebensmittel enthalten Wirkstoffe, die sich positiv auf den Zustand unserer Mitochondrien auswirken können. Bisher ist der Mensch noch nicht in den Jungbrunnen gefallen, aber wir arbeiten daran! Im zweiten Teil des Vortrags präsentiert sich das Unternehmen spermidinLIFE von The Longevity Labs. Das Unternehmen beschäftigt sich mit Nahrungsergänzungsmitteln, die die Zellerneuerung positiv beeinflussen. https://www.youtube-nocookie.com/embed/tX2hz-LqAio 2965 2021-10-06T16:05:11.000Z 2026-10-23T01:21:29.604Z https://longevityharbor.com/de/watch/tX2hz-LqAio Gesunde Ernährung – Gesunde Zellen – Gesundes Altern https://i.ytimg.com/vi/tX2hz-LqAio/hqdefault.jpg Das Team am Institut für Altersforschung der LFUI beschäftigt sich mit biochemischen Prozessen in Zellen, die zu vorzeitigen Alterungsprozessen im menschlichen Körper führen. In diesem sehr weiten Wissenschaftsfeld liegt deren Fokus speziell auf den Alterungsprozessen, die durch Funktionsstörungen von sogenannten Mitochondrien ausgelöst werden. Ähnlich wie unser Körper aus diversen Organen besteht, finden sich in unseren Zellen sogenannte Organellen, die individuelle Aufgaben in der Zelle übernehmen. Mitochondrien sind solche Organellen, die für unsere Zellen chemische Energie herstellen. Wir wissen heute, dass viele Erkrankungen durch gestörte Mitochondrien Funktionen zumindest mitverursacht werden. Im Zuge der Forschung interessiert das Team speziell auf die Rolle von ausgewählten Proteinen in der möglichen Entstehung von mitochondrialer Dysfunktion und natürlich auch der Aspekt der möglichen Medikation im Alter, aber auch der Vorbeugung in jüngeren Jahren. Diverse Lebensmittel enthalten Wirkstoffe, die sich positiv auf den Zustand unserer Mitochondrien auswirken können. Bisher ist der Mensch noch nicht in den Jungbrunnen gefallen, aber wir arbeiten daran! Im zweiten Teil des Vortrags präsentiert sich das Unternehmen spermidinLIFE von The Longevity Labs. Das Unternehmen beschäftigt sich mit Nahrungsergänzungsmitteln, die die Zellerneuerung positiv beeinflussen. https://www.youtube-nocookie.com/embed/tX2hz-LqAio 2965 2021-10-06T16:05:11.000Z 2026-10-23T01:21:29.604Z https://longevityharbor.com/en/watch/tYuSOIwwy-A Video description: six daily habits proposed for healthy aging after 70 https://i.ytimg.com/vi/tYuSOIwwy-A/hqdefault.jpg The description presents six daily habits said to support heart, brain, muscles, mobility, energy, sleep and well-being after 70; it reports no study results. https://www.youtube-nocookie.com/embed/tYuSOIwwy-A 1932 2026-09-30T18:53:20.000Z 2026-10-22T21:34:32.068Z https://longevityharbor.com/de/watch/tYuSOIwwy-A Videobeschreibung: sechs Alltagsgewohnheiten für gesundes Altern ab 70 https://i.ytimg.com/vi/tYuSOIwwy-A/hqdefault.jpg Die Beschreibung nennt sechs Alltagsgewohnheiten, die Herz, Gehirn, Muskeln, Mobilität, Energie, Schlaf und Wohlbefinden ab 70 unterstützen sollen; Studienergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/tYuSOIwwy-A 1932 2026-09-30T18:53:20.000Z 2026-10-22T21:34:32.068Z https://longevityharbor.com/en/watch/t_XRTCCdUFg Protein and exercise: The secrets of healthy aging? https://i.ytimg.com/vi/t_XRTCCdUFg/hqdefault.jpg As we age, our bodies undergo numerous changes, including a decline in muscle mass and cognitive function. For many of us, exercise and diet play crucial roles in maintaining our health and well-being. But how can the protein we eat affect our abilities to exercise and stay healthy as we age? It can be difficult to separate fact from fiction when it comes to the effects of protein. How much do we need? Is it better to eat protein before or after exercise? And what roles do protein and exercise play in brain function? In today’s episode, Jonathan is joined by Prof. Ben Wall, an expert in nutritional physiology at the University of Exeter. Together, they unpack the latest scientific research on the connection between protein consumption and exercise. Prof. Ben Wall shares his insights into the optimal amount and timing of protein intake for building and maintaining muscle mass, as well as the potential impact of exercise on cognitive function and brain health into later life. If you want to uncover the right foods for your body, head to joinZOE.com/podcast and get 10% off your personalized nutrition program. Mentioned in today’s episode: Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men: https://pubmed.ncbi.nlm.nih.gov/19056590/ Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle: https://pubmed.ncbi.nlm.nih.gov/15596483/ Food for our future: The nutritional science behind the sustainable fungal protein — mycoprotein: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131050/ Follow Ben on Twitter : https://twitter.com/benjamintwall Follow ZOE on Instagram: https://www.instagram.com/zoe/ Have an idea for a podcast? Contact Fascinate Productions to bring it to life. Episode transcripts are available here: https://joinzoe.com/learn/category/nutrition/podcast Is there a nutrition topic you’d like us to explore? Get in touch, and we’ll do our best to cover it: https://fascinateproductions.co.uk/contact/ Timecodes: 0 https://www.youtube-nocookie.com/embed/t_XRTCCdUFg 3629 2023-05-29T10:30:27.000Z 2026-10-22T17:43:36.928Z https://longevityharbor.com/de/watch/t_XRTCCdUFg Protein and exercise: The secrets of healthy aging? https://i.ytimg.com/vi/t_XRTCCdUFg/hqdefault.jpg As we age, our bodies undergo numerous changes, including a decline in muscle mass and cognitive function. For many of us, exercise and diet play crucial roles in maintaining our health and well-being. But how can the protein we eat affect our abilities to exercise and stay healthy as we age? It can be difficult to separate fact from fiction when it comes to the effects of protein. How much do we need? Is it better to eat protein before or after exercise? And what roles do protein and exercise play in brain function? In today’s episode, Jonathan is joined by Prof. Ben Wall, an expert in nutritional physiology at the University of Exeter. Together, they unpack the latest scientific research on the connection between protein consumption and exercise. Prof. Ben Wall shares his insights into the optimal amount and timing of protein intake for building and maintaining muscle mass, as well as the potential impact of exercise on cognitive function and brain health into later life. If you want to uncover the right foods for your body, head to joinZOE.com/podcast and get 10% off your personalized nutrition program. Mentioned in today’s episode: Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men: https://pubmed.ncbi.nlm.nih.gov/19056590/ Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle: https://pubmed.ncbi.nlm.nih.gov/15596483/ Food for our future: The nutritional science behind the sustainable fungal protein — mycoprotein: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131050/ Follow Ben on Twitter : https://twitter.com/benjamintwall Follow ZOE on Instagram: https://www.instagram.com/zoe/ Have an idea for a podcast? Contact Fascinate Productions to bring it to life. Episode transcripts are available here: https://joinzoe.com/learn/category/nutrition/podcast Is there a nutrition topic you’d like us to explore? Get in touch, and we’ll do our best to cover it: https://fascinateproductions.co.uk/contact/ Timecodes: 0 https://www.youtube-nocookie.com/embed/t_XRTCCdUFg 3629 2023-05-29T10:30:27.000Z 2026-10-22T17:43:36.928Z https://longevityharbor.com/en/watch/ta8s6YP8L_o Can Calorie Restriction Prolong Your Life? | Leonard Guarente | Big Think https://i.ytimg.com/vi/ta8s6YP8L_o/hqdefault.jpg Can Calorie Restriction Prolong Your Life? New videos DAILY: https://bigth.ink/youtube Join Big Think Edge for exclusive videos: https://bigth.ink/Edge ---------------------------------------------------------------------------------- There is no direct evidence yet that calorie-restricted diets retard human aging, but there are promising signs. However, if a 1,000-calorie diet makes you grumpy and lowers your sex drive, it may undo any good. ---------------------------------------------------------------------------------- Leonard Guarente: Dr. Leonard P. Guarente is an American biologist and director of MIT's Glenn Laboratory for the Science of Aging, where he is also a Novartis Professor of Biology. He is best known for his research on longevity and specifically for uncovering the gene in yeast that governs the organism's life span. He is the author of "Ageless Quest: One Scientist's Search for Genes That Prolong Youth," which was published in 2003 by Cold Spring Harbor Press. ---------------------------------------------------------------------------------- TRANSCRIPT: Question: What's the best diet for long life? Leonard Guarente: Well, I mean I think a low-calorie diet is probably a good thing. I think in humans we don't know; there's no data on what a low-calorie diet does in terms of diseases and longevity, as I said before. By analogy to rodents, you would think it would be a good thing. On the other hand, if it made you really miserable to eat 1,000 calories a day -- and people who are on that diet tend to be cold; they tend to have very low sex drive; they tend to in some cases be irritable -- and so if you're not happy, then that gets back to what we were saying earlier. You may be undoing some of the good that that diet would otherwise produce. So my feeling is to live sensibly. I mean, a word of advice that I think is good -- it's hard to follow -- but I think what everybody should do, if everybody could do this, it's the best you can do right now -- is decide what is your perfect weigh https://www.youtube-nocookie.com/embed/ta8s6YP8L_o 350 2012-04-24T01:06:48.000Z 2026-10-22T17:43:38.458Z https://longevityharbor.com/de/watch/ta8s6YP8L_o Can Calorie Restriction Prolong Your Life? | Leonard Guarente | Big Think https://i.ytimg.com/vi/ta8s6YP8L_o/hqdefault.jpg Can Calorie Restriction Prolong Your Life? New videos DAILY: https://bigth.ink/youtube Join Big Think Edge for exclusive videos: https://bigth.ink/Edge ---------------------------------------------------------------------------------- There is no direct evidence yet that calorie-restricted diets retard human aging, but there are promising signs. However, if a 1,000-calorie diet makes you grumpy and lowers your sex drive, it may undo any good. ---------------------------------------------------------------------------------- Leonard Guarente: Dr. Leonard P. Guarente is an American biologist and director of MIT's Glenn Laboratory for the Science of Aging, where he is also a Novartis Professor of Biology. He is best known for his research on longevity and specifically for uncovering the gene in yeast that governs the organism's life span. He is the author of "Ageless Quest: One Scientist's Search for Genes That Prolong Youth," which was published in 2003 by Cold Spring Harbor Press. ---------------------------------------------------------------------------------- TRANSCRIPT: Question: What's the best diet for long life? Leonard Guarente: Well, I mean I think a low-calorie diet is probably a good thing. I think in humans we don't know; there's no data on what a low-calorie diet does in terms of diseases and longevity, as I said before. By analogy to rodents, you would think it would be a good thing. On the other hand, if it made you really miserable to eat 1,000 calories a day -- and people who are on that diet tend to be cold; they tend to have very low sex drive; they tend to in some cases be irritable -- and so if you're not happy, then that gets back to what we were saying earlier. You may be undoing some of the good that that diet would otherwise produce. So my feeling is to live sensibly. I mean, a word of advice that I think is good -- it's hard to follow -- but I think what everybody should do, if everybody could do this, it's the best you can do right now -- is decide what is your perfect weigh https://www.youtube-nocookie.com/embed/ta8s6YP8L_o 350 2012-04-24T01:06:48.000Z 2026-10-22T17:43:38.458Z https://longevityharbor.com/en/watch/taZPhOz-mTU Human skin cells and a reported reset of age markers https://i.ytimg.com/vi/taZPhOz-mTU/hqdefault.jpg The creator describes a laboratory experiment in human skin cells: after temporary reprogramming, molecular age measurements reportedly fell by about 30 years. This is a claim about cultured cells and their markers, not people becoming 30 years younger. https://www.youtube-nocookie.com/embed/taZPhOz-mTU 842 2026-10-21T17:12:27.000Z 2026-10-22T20:11:23.479Z https://longevityharbor.com/de/watch/taZPhOz-mTU Menschliche Hautzellen und veränderte Altersmarker https://i.ytimg.com/vi/taZPhOz-mTU/hqdefault.jpg Der Ersteller beschreibt ein Laborexperiment mit menschlichen Hautzellen: Nach einer vorübergehenden Reprogrammierung sanken molekulare Altersmesswerte laut Beschreibung um etwa 30 Jahre. Es geht um kultivierte Zellen und ihre Marker, nicht um Menschen, die 30 Jahre jünger wurden. https://www.youtube-nocookie.com/embed/taZPhOz-mTU 842 2026-10-21T17:12:27.000Z 2026-10-22T20:11:23.479Z https://longevityharbor.com/en/watch/teGD6nrhIas Joan Mannick at ARDD2023 - Longevity Medicine Day: Longevity medicine therapeutics applied gero... https://i.ytimg.com/vi/teGD6nrhIas/hqdefault.jpg Joan Mannick, Co-Founder and CEO, Tornado Therapeutics, presents at the 10th Aging Research and Drug Discovery conference - Longevity Medicine Day: Longevity medicine therapeutics: applied geroprotective interventions, drug repurposing and discovery, RCTs https://www.youtube-nocookie.com/embed/teGD6nrhIas 1425 2023-10-26T18:50:03.000Z 2026-10-22T19:04:38.689Z https://longevityharbor.com/de/watch/teGD6nrhIas Joan Mannick at ARDD2023 - Longevity Medicine Day: Longevity medicine therapeutics applied gero... https://i.ytimg.com/vi/teGD6nrhIas/hqdefault.jpg Joan Mannick, Co-Founder and CEO, Tornado Therapeutics, presents at the 10th Aging Research and Drug Discovery conference - Longevity Medicine Day: Longevity medicine therapeutics: applied geroprotective interventions, drug repurposing and discovery, RCTs https://www.youtube-nocookie.com/embed/teGD6nrhIas 1425 2023-10-26T18:50:03.000Z 2026-10-22T19:04:38.689Z https://longevityharbor.com/en/watch/tk3aEJRl-vs The Science Behind Strength Training: What Research Tells Us About Healthy Aging https://i.ytimg.com/vi/tk3aEJRl-vs/hqdefault.jpg We all know that exercise is good for us, but what exactly are we supposed to do? In this one-hour presentation, you'll learn about the latest scientific evidence on the optimal exercise prescription to improve strength and function. You'll learn some of the best exercises you can do to promote healthy aging. This presentation is led by Dr. Katie Starr, assistant professor at the Duke School of Medicine and scientific advisor for Vivo (teamvivo.com). She received a B.A. in Exercise Science, M.S.M.A in Nutrition and Ph.D. in Nutrition from the University of Georgia. She served as a postdoctoral scholar at Duke University’s Center for Aging and Human Development and Geriatric Fellow at Durham VA Health Care System. Dr. Starr is a leader in the field of aging, nutrition and exercise and has published extensively on subjects spanning nutrition and exercise. She has also received grants to study such areas as perihabilitation in older veterans undergoing surgery, muscle health during obesity reduction, maintaining physical function using telehealth and joint health including osteoarthritis and rheumatoid arthritis. https://www.youtube-nocookie.com/embed/tk3aEJRl-vs 4263 2023-02-13T17:13:56.000Z 2026-10-22T19:02:25.517Z https://longevityharbor.com/de/watch/tk3aEJRl-vs The Science Behind Strength Training: What Research Tells Us About Healthy Aging https://i.ytimg.com/vi/tk3aEJRl-vs/hqdefault.jpg We all know that exercise is good for us, but what exactly are we supposed to do? In this one-hour presentation, you'll learn about the latest scientific evidence on the optimal exercise prescription to improve strength and function. You'll learn some of the best exercises you can do to promote healthy aging. This presentation is led by Dr. Katie Starr, assistant professor at the Duke School of Medicine and scientific advisor for Vivo (teamvivo.com). She received a B.A. in Exercise Science, M.S.M.A in Nutrition and Ph.D. in Nutrition from the University of Georgia. She served as a postdoctoral scholar at Duke University’s Center for Aging and Human Development and Geriatric Fellow at Durham VA Health Care System. Dr. Starr is a leader in the field of aging, nutrition and exercise and has published extensively on subjects spanning nutrition and exercise. She has also received grants to study such areas as perihabilitation in older veterans undergoing surgery, muscle health during obesity reduction, maintaining physical function using telehealth and joint health including osteoarthritis and rheumatoid arthritis. https://www.youtube-nocookie.com/embed/tk3aEJRl-vs 4263 2023-02-13T17:13:56.000Z 2026-10-22T19:02:25.517Z https://longevityharbor.com/en/watch/tke71MaAays Behind the Study: Drug Combo Targets Cancer & Senescent Cells, Extends Lifespan in Old Mice | Aging https://i.ytimg.com/vi/tke71MaAays/hqdefault.jpg Aging Editorial Board member Dr. Irina Conboy and Dr. Zachery Robinson from the Department of Bioengineering and QB3 Institute at the University of California, Berkeley, present their findings in the research paper, “Selective targeting of cancer and senescence via shared metabolic shifts extends lifespan of old mice.” #Aging #Lifespan #Presentation #Cancer #Senolytics #CellularSenescence #OpenAccess #PeerReviewed #Publishing #MedEd DOI - https://doi.org/10.18632/aging.206399 Corresponding author - Irina M. Conboy - irina@generationlab.co Longevity & Aging Series interview - https://www.youtube.com/watch?v=wllQRXPq_sY Abstract video - https://www.youtube.com/watch?v=7p5JMvy9Twg Abstract Eliminating both senescent and cancer cells through pharmacological intervention presents a powerful therapeutic strategy against aging and tumor progression. Navitoclax has emerged as a promising candidate with both senolytic and antitumor activity, but its clinical application remains limited due to dose-dependent thrombocytopenia and tumor-specific resistance. To overcome these limitations, we combined dichloroacetate and metformin with a 10-fold reduced dose of Navitoclax (ABT-263) and show that this pharmacology, termed, DMA, selectively targets the metabolic vulnerabilities underlying senescent and malignant cells. We demonstrate that DMA effectively ablates different types of senescent and cancer cells in vitro by exacerbating their defects in ATP production. Notably, the treatment is well tolerated by healthy human cells and in mice in vivo, and in fact improves the functional performance of aged mice after acute administration and extends lifespan after prolonged dosing. While the in vivo effects of DMA are yet to be fully explored, our findings suggest that it might represent a new, clinically viable way to combat cancer and senescence without toxicity to healthy cells and tissues. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206399 https://www.youtube-nocookie.com/embed/tke71MaAays 699 2026-10-15T17:40:36.000Z 2026-10-22T19:21:23.167Z https://longevityharbor.com/de/watch/tke71MaAays Behind the Study: Drug Combo Targets Cancer & Senescent Cells, Extends Lifespan in Old Mice | Aging https://i.ytimg.com/vi/tke71MaAays/hqdefault.jpg Aging Editorial Board member Dr. Irina Conboy and Dr. Zachery Robinson from the Department of Bioengineering and QB3 Institute at the University of California, Berkeley, present their findings in the research paper, “Selective targeting of cancer and senescence via shared metabolic shifts extends lifespan of old mice.” #Aging #Lifespan #Presentation #Cancer #Senolytics #CellularSenescence #OpenAccess #PeerReviewed #Publishing #MedEd DOI - https://doi.org/10.18632/aging.206399 Corresponding author - Irina M. Conboy - irina@generationlab.co Longevity & Aging Series interview - https://www.youtube.com/watch?v=wllQRXPq_sY Abstract video - https://www.youtube.com/watch?v=7p5JMvy9Twg Abstract Eliminating both senescent and cancer cells through pharmacological intervention presents a powerful therapeutic strategy against aging and tumor progression. Navitoclax has emerged as a promising candidate with both senolytic and antitumor activity, but its clinical application remains limited due to dose-dependent thrombocytopenia and tumor-specific resistance. To overcome these limitations, we combined dichloroacetate and metformin with a 10-fold reduced dose of Navitoclax (ABT-263) and show that this pharmacology, termed, DMA, selectively targets the metabolic vulnerabilities underlying senescent and malignant cells. We demonstrate that DMA effectively ablates different types of senescent and cancer cells in vitro by exacerbating their defects in ATP production. Notably, the treatment is well tolerated by healthy human cells and in mice in vivo, and in fact improves the functional performance of aged mice after acute administration and extends lifespan after prolonged dosing. While the in vivo effects of DMA are yet to be fully explored, our findings suggest that it might represent a new, clinically viable way to combat cancer and senescence without toxicity to healthy cells and tissues. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206399 https://www.youtube-nocookie.com/embed/tke71MaAays 699 2026-10-15T17:40:36.000Z 2026-10-22T19:21:23.167Z https://longevityharbor.com/en/watch/tpIu5kHwqRk Dunedin study description: epigenetic clocks and differing biological aging at age 38 https://i.ytimg.com/vi/tpIu5kHwqRk/hqdefault.jpg The description presents the Dunedin long-term study with over 1000 participants: two 38-year-olds can be biologically 28 and 61, and epigenetic clocks in DNA are said to reveal aging speed. https://www.youtube-nocookie.com/embed/tpIu5kHwqRk 515 2026-09-13T13:00:21.000Z 2026-10-22T22:16:39.479Z https://longevityharbor.com/de/watch/tpIu5kHwqRk Dunedin-Studienbeschreibung: epigenetische Uhren und unterschiedliches biologisches Altern mit 38 https://i.ytimg.com/vi/tpIu5kHwqRk/hqdefault.jpg Die Beschreibung stellt die Dunedin-Langzeitstudie mit über 1000 Teilnehmenden vor: Zwei 38-Jährige können biologisch 28 und 61 sein, und epigenetische Uhren in der DNA sollen die Alterungsgeschwindigkeit zeigen. https://www.youtube-nocookie.com/embed/tpIu5kHwqRk 515 2026-09-13T13:00:21.000Z 2026-10-22T22:16:39.479Z https://longevityharbor.com/en/watch/ts6BBSTrPvs Muscle aging study previewed: exercise, mitochondria and healthy aging https://i.ytimg.com/vi/ts6BBSTrPvs/hqdefault.jpg The description announces a video about a new muscle study on exercise, mitochondria and healthy aging, plus tips on training, nutrition and sleep and a look at substances still being researched. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/ts6BBSTrPvs 1493 2026-10-11T13:56:24.000Z 2026-10-22T20:34:44.209Z https://longevityharbor.com/de/watch/ts6BBSTrPvs Muskelalterungs-Studie angekündigt: Bewegung, Mitochondrien und gesundes Altern https://i.ytimg.com/vi/ts6BBSTrPvs/hqdefault.jpg Die Beschreibung kündigt ein Video über eine neue Muskelstudie zu Bewegung, Mitochondrien und gesundem Altern an, dazu Tipps zu Training, Ernährung und Schlaf und einen Blick auf noch erforschte Wirkstoffe. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/ts6BBSTrPvs 1493 2026-10-11T13:56:24.000Z 2026-10-22T20:34:44.209Z https://longevityharbor.com/en/watch/tsdpUvAjdWo Valter Longo: Fasting for Health and Longevity https://i.ytimg.com/vi/tsdpUvAjdWo/hqdefault.jpg What is the relationship between diet, chronic disease, and aging? Can we delay or reverse the effects of aging at the cellular level by following a fasting-mimicking diet? Listen in as Gordon speaks with Valter Longo of the Longevity Institute at USC about epigenetic reprogramming, turning on Yamanaka factors, and restoring our cells to a youthful state based on over 30 years of research on diet and fasting. Dr. Valter Longo is the Edna M. Jones Professor of Gerontology and Biological Sciences and Director of the Longevity Institute at the University of Southern California –Leonard Davis School of Gerontology, Los Angeles, one of the leading centers for research on aging and age-related disease. Dr. Longo is also the Director of the Longevity and Cancer Program at the IFOM Institute of Molecular Oncology in Milan, Italy. His studies focus on the fundamental mechanisms of aging in simple organisms and mice and on how these mechanisms can be translated to humans. The Longo laboratory recently published key findings on a 5 day periodic dietary intervention called Fasting Mimicking Diet (FMD), and showed in randomized clinical trials that FMD reduces the risk factors and markers associated with aging and diseases. Dr. Longo’s most recent studies focus on the use of FMD interventions to activate stem cell- based regeneration to promote longevity. He is the author of The Longevity Diet. Support the show (https://www.buckinstitute.org/donate/) https://www.youtube-nocookie.com/embed/tsdpUvAjdWo 1751 2024-05-01T12:17:23.000Z 2026-10-22T18:32:09.987Z https://longevityharbor.com/de/watch/tsdpUvAjdWo Valter Longo: Fasting for Health and Longevity https://i.ytimg.com/vi/tsdpUvAjdWo/hqdefault.jpg What is the relationship between diet, chronic disease, and aging? Can we delay or reverse the effects of aging at the cellular level by following a fasting-mimicking diet? Listen in as Gordon speaks with Valter Longo of the Longevity Institute at USC about epigenetic reprogramming, turning on Yamanaka factors, and restoring our cells to a youthful state based on over 30 years of research on diet and fasting. Dr. Valter Longo is the Edna M. Jones Professor of Gerontology and Biological Sciences and Director of the Longevity Institute at the University of Southern California –Leonard Davis School of Gerontology, Los Angeles, one of the leading centers for research on aging and age-related disease. Dr. Longo is also the Director of the Longevity and Cancer Program at the IFOM Institute of Molecular Oncology in Milan, Italy. His studies focus on the fundamental mechanisms of aging in simple organisms and mice and on how these mechanisms can be translated to humans. The Longo laboratory recently published key findings on a 5 day periodic dietary intervention called Fasting Mimicking Diet (FMD), and showed in randomized clinical trials that FMD reduces the risk factors and markers associated with aging and diseases. Dr. Longo’s most recent studies focus on the use of FMD interventions to activate stem cell- based regeneration to promote longevity. He is the author of The Longevity Diet. Support the show (https://www.buckinstitute.org/donate/) https://www.youtube-nocookie.com/embed/tsdpUvAjdWo 1751 2024-05-01T12:17:23.000Z 2026-10-22T18:32:09.987Z https://longevityharbor.com/en/watch/txTYAPOnwQ4 Carina Kern on aging as a systems problem, necrosis and proposed anti-necrotic therapy https://i.ytimg.com/vi/txTYAPOnwQ4/hqdefault.jpg In this conversation description, Carina Kern presents aging as a multifactorial systems problem and discusses necrosis as a possible driver of aging and chronic disease, plus a proposed first-in-class anti-necrotic therapy and AI use. https://www.youtube-nocookie.com/embed/txTYAPOnwQ4 3421 2026-01-05T17:01:35.000Z 2026-10-23T02:57:41.017Z https://longevityharbor.com/de/watch/txTYAPOnwQ4 Carina Kern über Altern als Systemproblem, Nekrose und eine vorgeschlagene Anti-Nekrose-Therapie https://i.ytimg.com/vi/txTYAPOnwQ4/hqdefault.jpg In dieser Gesprächsbeschreibung stellt Carina Kern Altern als multifaktorielles Systemproblem dar und erörtert Nekrose als möglichen Treiber von Altern und chronischen Krankheiten sowie eine vorgeschlagene Anti-Nekrose-Therapie der ersten Klasse und den Einsatz von KI. https://www.youtube-nocookie.com/embed/txTYAPOnwQ4 3421 2026-01-05T17:01:35.000Z 2026-10-23T02:57:41.017Z https://longevityharbor.com/en/watch/tzRvd2O47BU NMN is shown to have anti aging benefits and is the precursor to NAD https://i.ytimg.com/vi/tzRvd2O47BU/hqdefault.jpg NMN is shown to have anti aging benefits and is the precursor to NAD. Please do your research! #protecttheom #berdealzz https://www.youtube-nocookie.com/embed/tzRvd2O47BU 154 2025-12-14T01:52:21.000Z 2026-10-22T19:32:38.654Z https://longevityharbor.com/de/watch/tzRvd2O47BU NMN is shown to have anti aging benefits and is the precursor to NAD https://i.ytimg.com/vi/tzRvd2O47BU/hqdefault.jpg NMN is shown to have anti aging benefits and is the precursor to NAD. Please do your research! #protecttheom #berdealzz https://www.youtube-nocookie.com/embed/tzRvd2O47BU 154 2025-12-14T01:52:21.000Z 2026-10-22T19:32:38.654Z https://longevityharbor.com/en/watch/u3Ug-frt_wQ Podcast description links 90–120 weekly minutes of strength training to longevity in a 30-year study https://i.ytimg.com/vi/u3Ug-frt_wQ/hqdefault.jpg The description says a 30-year study of nearly 150,000 adults found 90–120 minutes of weekly strength training was associated with some of the greatest longevity benefits. It presents muscle as key to staying capable and independent after 40. https://www.youtube-nocookie.com/embed/u3Ug-frt_wQ 1409 2026-08-12T08:05:17.000Z 2026-10-22T23:06:16.135Z https://longevityharbor.com/de/watch/u3Ug-frt_wQ Podcast-Beschreibung verknüpft 90–120 wöchentliche Krafttrainingsminuten mit Langlebigkeit in einer https://i.ytimg.com/vi/u3Ug-frt_wQ/hqdefault.jpg Laut Beschreibung ergab eine 30-Jahres-Studie mit fast 150.000 Erwachsenen, dass 90–120 Minuten Krafttraining pro Woche mit einigen der größten Langlebigkeitsvorteilen verbunden waren. Sie stellt Muskeln als wichtig für Fähigkeit und Selbstständigkeit nach 40 dar. https://www.youtube-nocookie.com/embed/u3Ug-frt_wQ 1409 2026-08-12T08:05:17.000Z 2026-10-22T23:06:16.135Z https://longevityharbor.com/en/watch/uDAmKdjw_d4 Longevity einfach erklärt: 5 Säulen für gesundes Altern https://i.ytimg.com/vi/uDAmKdjw_d4/hqdefault.jpg **Longevity einfach erklärt: Wie kannst du möglichst lange gesund, fit und selbstständig bleiben?** Erfahre, welche fünf Säulen für gesundes Altern wichtig sind und warum Muskeltraining dabei eine besondere Rolle spielt. **Du möchtest deine Fitness langfristig verbessern?** Informiere dich über unsere Trainings- und Beratungsmöglichkeiten bei active – therapie + training: https://active-mosel.de/?utm_source=youtube&utm_medium=video&utm_campaign=longevity_5_saeulen ## Was bedeutet Longevity? Longevity bedeutet Langlebigkeit. Doch entscheidend ist nicht nur, wie lange wir leben, sondern auch, wie gesund, beweglich und selbstständig wir diese Jahre verbringen. In diesem Video erklären wir, warum Longevity weit mehr ist als Nahrungsergänzungsmittel, Eisbäder oder aufwendige Gesundheitsroutinen. Wir beschäftigen uns mit den wissenschaftlichen Grundlagen des gesunden Alterns und zeigen dir, welche Bereiche du selbst beeinflussen kannst. ## Lifespan und Healthspan – was ist der Unterschied? Die Lifespan beschreibt die gesamte Lebensdauer eines Menschen. Die Healthspan bezeichnet die Lebensjahre, die wir bei möglichst guter Gesundheit verbringen. Das Ziel einer gesundheitsorientierten Lebensweise ist deshalb nicht nur eine möglichst hohe Lebenserwartung, sondern vor allem eine möglichst lange Phase körperlicher und geistiger Selbstständigkeit. ## Die 5 Säulen für gesundes Altern **1. Bewegung und Muskeltraining** Unsere Muskulatur ist nicht nur für Kraft und Bewegung wichtig. Sie spielt auch eine wesentliche Rolle im Stoffwechsel. Regelmäßiges Krafttraining kann helfen, Muskelmasse, körperliche Leistungsfähigkeit und Selbstständigkeit im Alter zu erhalten. **2. Ernährung und Stoffwechsel** Eine ausgewogene Ernährung und langfristig sinnvolle Gewohnheiten sind wichtiger als kurzfristige Diäten oder einzelne vermeintliche Superfoods. **3. Schlaf und Regeneration** Ausreichender Schlaf unterstützt zahlreiche körperliche und geistige Regenerationsprozesse. Auch Stressmanagement gehört zu einer nachhaltigen G https://www.youtube-nocookie.com/embed/uDAmKdjw_d4 398 2026-10-16T08:48:35.000Z 2026-10-22T17:43:36.028Z https://longevityharbor.com/de/watch/uDAmKdjw_d4 Longevity einfach erklärt: 5 Säulen für gesundes Altern https://i.ytimg.com/vi/uDAmKdjw_d4/hqdefault.jpg **Longevity einfach erklärt: Wie kannst du möglichst lange gesund, fit und selbstständig bleiben?** Erfahre, welche fünf Säulen für gesundes Altern wichtig sind und warum Muskeltraining dabei eine besondere Rolle spielt. **Du möchtest deine Fitness langfristig verbessern?** Informiere dich über unsere Trainings- und Beratungsmöglichkeiten bei active – therapie + training: https://active-mosel.de/?utm_source=youtube&utm_medium=video&utm_campaign=longevity_5_saeulen ## Was bedeutet Longevity? Longevity bedeutet Langlebigkeit. Doch entscheidend ist nicht nur, wie lange wir leben, sondern auch, wie gesund, beweglich und selbstständig wir diese Jahre verbringen. In diesem Video erklären wir, warum Longevity weit mehr ist als Nahrungsergänzungsmittel, Eisbäder oder aufwendige Gesundheitsroutinen. Wir beschäftigen uns mit den wissenschaftlichen Grundlagen des gesunden Alterns und zeigen dir, welche Bereiche du selbst beeinflussen kannst. ## Lifespan und Healthspan – was ist der Unterschied? Die Lifespan beschreibt die gesamte Lebensdauer eines Menschen. Die Healthspan bezeichnet die Lebensjahre, die wir bei möglichst guter Gesundheit verbringen. Das Ziel einer gesundheitsorientierten Lebensweise ist deshalb nicht nur eine möglichst hohe Lebenserwartung, sondern vor allem eine möglichst lange Phase körperlicher und geistiger Selbstständigkeit. ## Die 5 Säulen für gesundes Altern **1. Bewegung und Muskeltraining** Unsere Muskulatur ist nicht nur für Kraft und Bewegung wichtig. Sie spielt auch eine wesentliche Rolle im Stoffwechsel. Regelmäßiges Krafttraining kann helfen, Muskelmasse, körperliche Leistungsfähigkeit und Selbstständigkeit im Alter zu erhalten. **2. Ernährung und Stoffwechsel** Eine ausgewogene Ernährung und langfristig sinnvolle Gewohnheiten sind wichtiger als kurzfristige Diäten oder einzelne vermeintliche Superfoods. **3. Schlaf und Regeneration** Ausreichender Schlaf unterstützt zahlreiche körperliche und geistige Regenerationsprozesse. Auch Stressmanagement gehört zu einer nachhaltigen G https://www.youtube-nocookie.com/embed/uDAmKdjw_d4 398 2026-10-16T08:48:35.000Z 2026-10-22T17:43:36.028Z https://longevityharbor.com/en/watch/uG1EESkr5vY Fasten-Geheimnis: Mehr Energie & Muskeln! (So geht's richtig!) https://i.ytimg.com/vi/uG1EESkr5vY/hqdefault.jpg Entdecke, wie **Fasten** deine Muskelgesundheit und Langlebigkeit fördert! Wir erklären den metabolischen Schalter, Muskelspareffekte und wie du richtig fastest. Vermeide Energietiefs und erreiche maximale Ketose. Werde Teil unserer Telegram-Gruppe für exklusive Inhalte! #Fasten #Muskelgesundheit #Langlebigkeit #MetabolischerSchalter #Ketose #Ernährung #Gesundheit #Wohlbefinden #TelegramGruppe #Energietief https://www.youtube-nocookie.com/embed/uG1EESkr5vY 102 2025-05-02T08:45:38.000Z 2026-10-22T17:43:37.685Z https://longevityharbor.com/de/watch/uG1EESkr5vY Fasten-Geheimnis: Mehr Energie & Muskeln! (So geht's richtig!) https://i.ytimg.com/vi/uG1EESkr5vY/hqdefault.jpg Entdecke, wie **Fasten** deine Muskelgesundheit und Langlebigkeit fördert! Wir erklären den metabolischen Schalter, Muskelspareffekte und wie du richtig fastest. Vermeide Energietiefs und erreiche maximale Ketose. Werde Teil unserer Telegram-Gruppe für exklusive Inhalte! #Fasten #Muskelgesundheit #Langlebigkeit #MetabolischerSchalter #Ketose #Ernährung #Gesundheit #Wohlbefinden #TelegramGruppe #Energietief https://www.youtube-nocookie.com/embed/uG1EESkr5vY 102 2025-05-02T08:45:38.000Z 2026-10-22T17:43:37.685Z https://longevityharbor.com/en/watch/uGNLrWxsTiw How Micronutrients & Exercise Ameliorate Aging | Dr. Rhonda Patrick https://i.ytimg.com/vi/uGNLrWxsTiw/hqdefault.jpg This episode comes from my keynote lecture at the American Academy of Anti-Aging Medicine LongevityFest 2023, in which I describe several powerful health habits that delay biological aging and improve healthspan. The core idea: You don't have to move mountains to make a big impact on aging. Starting with a few key areas of focus (vitamin D, magnesium, omega-3s, and vigorous exercise) can make a big difference. Thanks @A4MEvents for having me! *Get the 9-page Cognitive Enhancement Blueprint:* https://bdnfprotocols.com/ *CHAPTERS:* (01:38) Vitamin D (05:58) How vitamin D deficiency affects mortality risk (09:24) Optimal vitamin D levels & supplementation (11:10) Why magnesium deficiency impairs DNA damage repair (14:50) Dangers of inadequate omega-3 intake (17:07) The correct omega-3 index level (21:32) How to correct vitamin D, omega-3, & magnesium inadequacies (23:17) Vigorous exercise is the best longevity drug (24:50) How increasing VO2 max affects life expectancy (29:36) Protocols for increasing VO2 max (32:27) How to measure VO2 max (33:34) What it takes to reverse 20 years of heart aging (36:31) Blood pressure benefits of vigorous exercise (37:48) The BDNF brain benefits of vigorous exercise (40:58) How vigorous exercise improves focus & attention (42:11) Exercise protocols for maximizing BDNF (43:13) Anti-cancer effects of vigorous exercise (45:30) Exercise snacks ​ EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/micronutrients-exercise-ameliorate-aging?utm_source=youtube&utm_medium=youtube&utm_campaign=longevity_fest_podcast PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=longevity_fest_podcast Apple Podcasts: https://podcasts.apple.com/us/podcast/086-how-micronutrients-exercise-ameliorate-aging-dr/id818198322?i=1000648204449 Spotify: https://open.spotify.com/episode/10VXKSmTQj2ZbAQrPylM24?si=1380eccf28d24dcc RSS: https://podcast.foundmyfitness.com/rss.xml Just Me playlist: https://www.youtube.com/play https://www.youtube-nocookie.com/embed/uGNLrWxsTiw 3141 2024-03-06T16:00:06.000Z 2026-10-22T17:24:38.505Z https://longevityharbor.com/de/watch/uGNLrWxsTiw How Micronutrients & Exercise Ameliorate Aging | Dr. Rhonda Patrick https://i.ytimg.com/vi/uGNLrWxsTiw/hqdefault.jpg This episode comes from my keynote lecture at the American Academy of Anti-Aging Medicine LongevityFest 2023, in which I describe several powerful health habits that delay biological aging and improve healthspan. The core idea: You don't have to move mountains to make a big impact on aging. Starting with a few key areas of focus (vitamin D, magnesium, omega-3s, and vigorous exercise) can make a big difference. Thanks @A4MEvents for having me! *Get the 9-page Cognitive Enhancement Blueprint:* https://bdnfprotocols.com/ *CHAPTERS:* (01:38) Vitamin D (05:58) How vitamin D deficiency affects mortality risk (09:24) Optimal vitamin D levels & supplementation (11:10) Why magnesium deficiency impairs DNA damage repair (14:50) Dangers of inadequate omega-3 intake (17:07) The correct omega-3 index level (21:32) How to correct vitamin D, omega-3, & magnesium inadequacies (23:17) Vigorous exercise is the best longevity drug (24:50) How increasing VO2 max affects life expectancy (29:36) Protocols for increasing VO2 max (32:27) How to measure VO2 max (33:34) What it takes to reverse 20 years of heart aging (36:31) Blood pressure benefits of vigorous exercise (37:48) The BDNF brain benefits of vigorous exercise (40:58) How vigorous exercise improves focus & attention (42:11) Exercise protocols for maximizing BDNF (43:13) Anti-cancer effects of vigorous exercise (45:30) Exercise snacks ​ EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/micronutrients-exercise-ameliorate-aging?utm_source=youtube&utm_medium=youtube&utm_campaign=longevity_fest_podcast PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=longevity_fest_podcast Apple Podcasts: https://podcasts.apple.com/us/podcast/086-how-micronutrients-exercise-ameliorate-aging-dr/id818198322?i=1000648204449 Spotify: https://open.spotify.com/episode/10VXKSmTQj2ZbAQrPylM24?si=1380eccf28d24dcc RSS: https://podcast.foundmyfitness.com/rss.xml Just Me playlist: https://www.youtube.com/play https://www.youtube-nocookie.com/embed/uGNLrWxsTiw 3141 2024-03-06T16:00:06.000Z 2026-10-22T17:24:38.505Z https://longevityharbor.com/en/watch/uHRSMzNdOi8 Review: Opposing and Synergistic Roles of Cellular Senescence and Stemness https://i.ytimg.com/vi/uHRSMzNdOi8/hqdefault.jpg A review published May 30, 2026, describes senescence and stemness as opposing yet homeostatic forces, with synergy mainly in cancer. https://www.youtube-nocookie.com/embed/uHRSMzNdOi8 93 2026-06-29T14:42:09.000Z 2026-10-22T23:42:19.870Z https://longevityharbor.com/de/watch/uHRSMzNdOi8 Review: Gegenläufige und synergistische Rollen von zellulärer Seneszenz und Stammzellcharakter https://i.ytimg.com/vi/uHRSMzNdOi8/hqdefault.jpg Ein am 30. Mai 2026 veröffentlichtes Review beschreibt Seneszenz und Stammzellcharakter als gegenläufige, aber homöostatische Kräfte, mit Synergie vor allem bei Krebs. https://www.youtube-nocookie.com/embed/uHRSMzNdOi8 93 2026-06-29T14:42:09.000Z 2026-10-22T23:42:19.870Z https://longevityharbor.com/en/watch/uK3hXXaXr-4 Video description: biological age clocks, lifestyle factors and drug research https://i.ytimg.com/vi/uK3hXXaXr-4/hqdefault.jpg The description says the video explains how scientists measure biological versus chronological age, what epigenetic clocks predict, which lifestyle factors are linked to faster or slower aging, and why metformin and rapamycin are not yet established anti-aging interventions. https://www.youtube-nocookie.com/embed/uK3hXXaXr-4 3239 2026-08-20T22:00:01.000Z 2026-10-22T22:54:07.047Z https://longevityharbor.com/de/watch/uK3hXXaXr-4 Videobeschreibung: biologische Altersuhren, Lebensstilfaktoren und Arzneimittelforschung https://i.ytimg.com/vi/uK3hXXaXr-4/hqdefault.jpg Laut Beschreibung erklärt das Video, wie Wissenschaftler biologisches und chronologisches Alter messen, was epigenetische Uhren vorhersagen, welche Lebensstilfaktoren mit schnellerem oder langsamerem Altern zusammenhängen und warum Metformin und Rapamycin noch keine etablierten Anti-Aging-Interventionen sind. https://www.youtube-nocookie.com/embed/uK3hXXaXr-4 3239 2026-08-20T22:00:01.000Z 2026-10-22T22:54:07.047Z https://longevityharbor.com/en/watch/uKAscTpNbXE Exploring the Science of Aging and Longevity by Suramya at Zugrama Longevity Week https://i.ytimg.com/vi/uKAscTpNbXE/hqdefault.jpg The session provided a comprehensive overview of aging, longevity research, and the latest advancements in the field. Suramya structured the talk into four key areas: 1. Introduction to Longevity Science - Defined longevity medicine and its interdisciplinary nature, covering geroscience (the biology of aging), biomarkers, and therapeutic development. - Highlighted the WHO's "Decade of Healthy Aging" initiative, emphasizing the global shift toward an aging population and the importance of maintaining functional and intrinsic capacity (e.g., mobility, cognition, independence) in older adults. 2. Markers of Aging - Discussed the hallmarks of aging, including telomere shortening, genomic instability, epigenetic changes, mitochondrial dysfunction, and cellular senescence (cells that stop dividing but remain metabolically active). - Explained how these markers contribute to age-related diseases and systemic decline. 3. Targeting Aging for Therapeutics - Explored strategies like senolytics (drugs that eliminate senescent cells), lifestyle interventions (diet, exercise, sleep), and emerging therapies such as CAR T-cell therapy and cellular reprogramming. - Stressed the need for personalized approaches due to heterogeneity in aging across individuals and populations. 4. Future of Longevity Research - Highlighted large-scale global studies (e.g., UK Biobank, Longitudinal Aging Study in India) and the role of AI in biomarker discovery and drug development. - Emphasized gaps in research, such as the lack of Indian-specific health data and the need for cross-disciplinary collaboration between longevity science and lifestyle medicine. Key Takeaways: - Aging is driven by interconnected biological processes at molecular, cellular, and systemic levels. - Interventions like reducing inflammation, optimizing sleep, and maintaining gut health can promote healthy aging. - Cutting-edge therapies (e.g., senolytics, stem cell treatments) hold promise but require further validat https://www.youtube-nocookie.com/embed/uKAscTpNbXE 5763 2025-04-26T11:09:15.000Z 2026-10-22T17:43:40.202Z https://longevityharbor.com/de/watch/uKAscTpNbXE Exploring the Science of Aging and Longevity by Suramya at Zugrama Longevity Week https://i.ytimg.com/vi/uKAscTpNbXE/hqdefault.jpg The session provided a comprehensive overview of aging, longevity research, and the latest advancements in the field. Suramya structured the talk into four key areas: 1. Introduction to Longevity Science - Defined longevity medicine and its interdisciplinary nature, covering geroscience (the biology of aging), biomarkers, and therapeutic development. - Highlighted the WHO's "Decade of Healthy Aging" initiative, emphasizing the global shift toward an aging population and the importance of maintaining functional and intrinsic capacity (e.g., mobility, cognition, independence) in older adults. 2. Markers of Aging - Discussed the hallmarks of aging, including telomere shortening, genomic instability, epigenetic changes, mitochondrial dysfunction, and cellular senescence (cells that stop dividing but remain metabolically active). - Explained how these markers contribute to age-related diseases and systemic decline. 3. Targeting Aging for Therapeutics - Explored strategies like senolytics (drugs that eliminate senescent cells), lifestyle interventions (diet, exercise, sleep), and emerging therapies such as CAR T-cell therapy and cellular reprogramming. - Stressed the need for personalized approaches due to heterogeneity in aging across individuals and populations. 4. Future of Longevity Research - Highlighted large-scale global studies (e.g., UK Biobank, Longitudinal Aging Study in India) and the role of AI in biomarker discovery and drug development. - Emphasized gaps in research, such as the lack of Indian-specific health data and the need for cross-disciplinary collaboration between longevity science and lifestyle medicine. Key Takeaways: - Aging is driven by interconnected biological processes at molecular, cellular, and systemic levels. - Interventions like reducing inflammation, optimizing sleep, and maintaining gut health can promote healthy aging. - Cutting-edge therapies (e.g., senolytics, stem cell treatments) hold promise but require further validat https://www.youtube-nocookie.com/embed/uKAscTpNbXE 5763 2025-04-26T11:09:15.000Z 2026-10-22T17:43:40.202Z https://longevityharbor.com/en/watch/uPagbVAMKZo Healthy aging – Was gibt es Neues vom Chef des Buck Instituts Eric Verdin? https://i.ytimg.com/vi/uPagbVAMKZo/hqdefault.jpg Sponsor dieser Folge ist Kaneka Erfahre hier mehr: https://www.kaneka-ubiquinol.com/ Wir danken Kaneka für die Unterstützung. Die Podcast-Inhalte bleiben aber stets unabhängig, das ist uns wichtig. ____________________________________________________________________________________________ Heute spreche ich mit Professor Eric Verdin, einem der weltweit führenden Altersforscher und Präsidenten des Buck Institute for Research on Aging. Wir sprechen über nichts Geringeres als die Zukunft der Medizin: Wie KI, komplexe Biomarker und präventive Diagnostik unsere Gesundheit revolutionieren könnten – lange bevor Krankheiten entstehen. Eric gibt Einblicke in die PATH-Studie, diskutiert die Potenziale von Ketonkörpern gegen Alzheimer und erklärt, warum GLP-1-Rezeptor-Agonisten als erste globale Anti-Aging-Medikamente gelten könnten. Wissenschaft zum Staunen – verständlich und mitreißend erklärt. In dieser Folge sprechen wir u.a. über folgende Themen: - Wie können KI und Big Data die präventive Medizin revolutionieren? - Warum sind klassische Blutwerte nicht mehr ausreichend für eine moderne Gesundheitsdiagnostik? - Wie lassen sich Herzinfarkt und Alzheimer schon 15 Jahre im Voraus vorhersagen? - Was macht Ketonkörper und Ketoneester zu potenziellen Schutzfaktoren gegen Demenz? - Sind ketogene Diäten alltagstauglich – oder braucht es neue Wege zur Ketose? - Könnten GLP-1-Rezeptor-Agonisten wie Ozempic das erste echte Anti-Aging-Medikament sein? - Warum könnte die Insulinsensitivität der Schlüssel zur Lebensverlängerung sein? - Sind Mäuse als Modellorganismen für die Alternsforschung noch zeitgemäß – oder brauchen wir mehr Humanstudien? - Welche Bedeutung haben Biomarker des Alterns für personalisierte Medizin? - Weshalb wird chronische Entzündung als zentrales Kennzeichen des Alterns angesehen? - Welche Rolle spielt das Immunsystem beim biologischen Altern – und wie können wir es gezielt unterstützen? - Warum ist die Kommunikation wissenschaftlicher Erkenntnisse heute wichtiger denn je? Weitere Infor https://www.youtube-nocookie.com/embed/uPagbVAMKZo 2276 2025-07-25T04:59:32.000Z 2026-10-22T17:43:39.278Z https://longevityharbor.com/de/watch/uPagbVAMKZo Healthy aging – Was gibt es Neues vom Chef des Buck Instituts Eric Verdin? https://i.ytimg.com/vi/uPagbVAMKZo/hqdefault.jpg Sponsor dieser Folge ist Kaneka Erfahre hier mehr: https://www.kaneka-ubiquinol.com/ Wir danken Kaneka für die Unterstützung. Die Podcast-Inhalte bleiben aber stets unabhängig, das ist uns wichtig. ____________________________________________________________________________________________ Heute spreche ich mit Professor Eric Verdin, einem der weltweit führenden Altersforscher und Präsidenten des Buck Institute for Research on Aging. Wir sprechen über nichts Geringeres als die Zukunft der Medizin: Wie KI, komplexe Biomarker und präventive Diagnostik unsere Gesundheit revolutionieren könnten – lange bevor Krankheiten entstehen. Eric gibt Einblicke in die PATH-Studie, diskutiert die Potenziale von Ketonkörpern gegen Alzheimer und erklärt, warum GLP-1-Rezeptor-Agonisten als erste globale Anti-Aging-Medikamente gelten könnten. Wissenschaft zum Staunen – verständlich und mitreißend erklärt. In dieser Folge sprechen wir u.a. über folgende Themen: - Wie können KI und Big Data die präventive Medizin revolutionieren? - Warum sind klassische Blutwerte nicht mehr ausreichend für eine moderne Gesundheitsdiagnostik? - Wie lassen sich Herzinfarkt und Alzheimer schon 15 Jahre im Voraus vorhersagen? - Was macht Ketonkörper und Ketoneester zu potenziellen Schutzfaktoren gegen Demenz? - Sind ketogene Diäten alltagstauglich – oder braucht es neue Wege zur Ketose? - Könnten GLP-1-Rezeptor-Agonisten wie Ozempic das erste echte Anti-Aging-Medikament sein? - Warum könnte die Insulinsensitivität der Schlüssel zur Lebensverlängerung sein? - Sind Mäuse als Modellorganismen für die Alternsforschung noch zeitgemäß – oder brauchen wir mehr Humanstudien? - Welche Bedeutung haben Biomarker des Alterns für personalisierte Medizin? - Weshalb wird chronische Entzündung als zentrales Kennzeichen des Alterns angesehen? - Welche Rolle spielt das Immunsystem beim biologischen Altern – und wie können wir es gezielt unterstützen? - Warum ist die Kommunikation wissenschaftlicher Erkenntnisse heute wichtiger denn je? Weitere Infor https://www.youtube-nocookie.com/embed/uPagbVAMKZo 2276 2025-07-25T04:59:32.000Z 2026-10-22T17:43:39.278Z https://longevityharbor.com/en/watch/uZiv_0nzv24 Cellular Senescence & Cancer https://i.ytimg.com/vi/uZiv_0nzv24/hqdefault.jpg Judith Campisi, PhD and professor at the Buck Institute, sits down with Culminant Health to break down the evolution of senescent cells in the human body. https://www.youtube-nocookie.com/embed/uZiv_0nzv24 146 2018-03-23T18:17:44.000Z 2026-10-23T02:56:02.483Z https://longevityharbor.com/de/watch/uZiv_0nzv24 Cellular Senescence & Cancer https://i.ytimg.com/vi/uZiv_0nzv24/hqdefault.jpg Judith Campisi, PhD and professor at the Buck Institute, sits down with Culminant Health to break down the evolution of senescent cells in the human body. https://www.youtube-nocookie.com/embed/uZiv_0nzv24 146 2018-03-23T18:17:44.000Z 2026-10-23T02:56:02.483Z https://longevityharbor.com/en/watch/ujS1BHmA1n4 Rapamycin vs. Metformin: Description Compares Two Anti-Aging Drugs https://i.ytimg.com/vi/ujS1BHmA1n4/hqdefault.jpg The description frames rapamycin and metformin as serving different purposes rather than naming one winner; it reports no trial results and gives no dosing. https://www.youtube-nocookie.com/embed/ujS1BHmA1n4 618 2026-08-30T14:15:03.000Z 2026-10-22T22:39:14.938Z https://longevityharbor.com/de/watch/ujS1BHmA1n4 Rapamycin gegen Metformin: Beschreibung vergleicht zwei Anti-Aging-Mittel https://i.ytimg.com/vi/ujS1BHmA1n4/hqdefault.jpg Die Beschreibung ordnet Rapamycin und Metformin unterschiedlichen Zwecken zu, statt einen Sieger zu nennen; sie berichtet keine Studienergebnisse und keine Dosierung. https://www.youtube-nocookie.com/embed/ujS1BHmA1n4 618 2026-08-30T14:15:03.000Z 2026-10-22T22:39:14.938Z https://longevityharbor.com/en/watch/un3--vdM4bE Celebrity Nutritionist Ryan Fernando Delves into Anti-Aging, Sugar Craving&Restaurant Food Concerns https://i.ytimg.com/vi/un3--vdM4bE/hqdefault.jpg In this podcast, Ryan Fernando delves into optimal food choices for gut health and youthful appearance, sugar consumption trends, the significance of fermented foods, and the rationale behind avoiding restaurant dining! @celebritynutritionistryan #GutFeeling #DrPal #ryanfernando #gutfeelingpodcast #healthyeating #healthyhabits #timerestrictedeating #intermittentfasting #eatclean #askdocpal #gutarmy Subscribe to my channel: @DrPal to never miss a notification! Follow me on Instagram: https://www.instagram.com/dr.pal.manickam/ Medical comedy (Medcom) shows: I love doing medical comedy (medcom) stand-up shows. This is a wonderful opportunity to meet you all in person and also to promote awareness of a healthy lifestyle. My upcoming show details: 📍Raleigh - 16th March 2024 🔗 https://www.tugoz.com/events/bldg18/medcom-show-raleigh 📍Charlotte - 17th March 2024 🔗https://www.tugoz.com/events/bldg18/medcom-show-charlotte 📍San Antonio - 6th April 2024 🔗 https://www.tugoz.com/events/bldg18/medcom-show-sa 📍Austin - 7th April 2024 🔗https://www.tugoz.com/events/bldg18/medcom-show-austin #medcom #DrPalMedcomShow For Collabs & Enquiries: Email: askdocpal@gmail.com Also, you can listen to my podcast on your favourite audio platforms: ✅ Spotify: https://podcasters.spotify.com/pod/show/gut-feeling-with-drpal ✅ Amazon Music: https://music.amazon.co.uk/podcasts/77d5c815-b58e-4b78-a7ab-db39b4753ffc/gut-feeling-with-dr-pal Subscribe to our 2 new channels for Podcast Shorts & Clips: @GutFeelingPodcastShorts @DrPalPodcast 00:00 Coming up on the podcast 01:37 Dr.Ryan Fernando's secret to staying young 06:02 Controlling your visceral fat is the key 08:00 Visceral Fat 09:23 The difference between subcutaneous and visceral fat 11:28 The dangers of Palm oil 13:24 Your body is your most expensive real estate 14:29 We are eating more than we require! 16:44 How celebrities plan their schedule to stay fit 18:24 Checking your body age through visceral fat 21:00 The ideal body fat percentage! 24:35 How to manage weight https://www.youtube-nocookie.com/embed/un3--vdM4bE 4157 2024-03-15T10:01:38.000Z 2026-10-22T19:04:44.838Z https://longevityharbor.com/de/watch/un3--vdM4bE Celebrity Nutritionist Ryan Fernando Delves into Anti-Aging, Sugar Craving&Restaurant Food Concerns https://i.ytimg.com/vi/un3--vdM4bE/hqdefault.jpg In this podcast, Ryan Fernando delves into optimal food choices for gut health and youthful appearance, sugar consumption trends, the significance of fermented foods, and the rationale behind avoiding restaurant dining! @celebritynutritionistryan #GutFeeling #DrPal #ryanfernando #gutfeelingpodcast #healthyeating #healthyhabits #timerestrictedeating #intermittentfasting #eatclean #askdocpal #gutarmy Subscribe to my channel: @DrPal to never miss a notification! Follow me on Instagram: https://www.instagram.com/dr.pal.manickam/ Medical comedy (Medcom) shows: I love doing medical comedy (medcom) stand-up shows. This is a wonderful opportunity to meet you all in person and also to promote awareness of a healthy lifestyle. My upcoming show details: 📍Raleigh - 16th March 2024 🔗 https://www.tugoz.com/events/bldg18/medcom-show-raleigh 📍Charlotte - 17th March 2024 🔗https://www.tugoz.com/events/bldg18/medcom-show-charlotte 📍San Antonio - 6th April 2024 🔗 https://www.tugoz.com/events/bldg18/medcom-show-sa 📍Austin - 7th April 2024 🔗https://www.tugoz.com/events/bldg18/medcom-show-austin #medcom #DrPalMedcomShow For Collabs & Enquiries: Email: askdocpal@gmail.com Also, you can listen to my podcast on your favourite audio platforms: ✅ Spotify: https://podcasters.spotify.com/pod/show/gut-feeling-with-drpal ✅ Amazon Music: https://music.amazon.co.uk/podcasts/77d5c815-b58e-4b78-a7ab-db39b4753ffc/gut-feeling-with-dr-pal Subscribe to our 2 new channels for Podcast Shorts & Clips: @GutFeelingPodcastShorts @DrPalPodcast 00:00 Coming up on the podcast 01:37 Dr.Ryan Fernando's secret to staying young 06:02 Controlling your visceral fat is the key 08:00 Visceral Fat 09:23 The difference between subcutaneous and visceral fat 11:28 The dangers of Palm oil 13:24 Your body is your most expensive real estate 14:29 We are eating more than we require! 16:44 How celebrities plan their schedule to stay fit 18:24 Checking your body age through visceral fat 21:00 The ideal body fat percentage! 24:35 How to manage weight https://www.youtube-nocookie.com/embed/un3--vdM4bE 4157 2024-03-15T10:01:38.000Z 2026-10-22T19:04:44.838Z https://longevityharbor.com/en/watch/uquZph42iSU DNA Methylation: Timekeeper of Biological Age. Epigenetic clock https://i.ytimg.com/vi/uquZph42iSU/hqdefault.jpg Webinar by Steve Horvath on the epigenetic clock method from July 26, 2018. DNA methylation data have enabled accurate age estimates for any tissue across the entire life course. These 'epigenetic clocks' link developmental and maintenance processes to biological ageing, giving rise to a unified theory of life course. Citations a) Horvath (2013) DNA methylation age of human tissues and cell types. Genome Biology.PMID: 24138928 PMCID: PMC4015143 DOI: 10.1186/gb-2013-14-10-r115 https://www.ncbi.nlm.nih.gov/pubmed/24138928 b) Horvath and Raj (2018) DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nat Rev Genet. PMID: 29643443 DOI: 10.1038/s41576-018-0004-3 https://www.youtube-nocookie.com/embed/uquZph42iSU 4836 2018-07-27T19:57:44.000Z 2026-10-22T17:43:35.156Z https://longevityharbor.com/de/watch/uquZph42iSU DNA Methylation: Timekeeper of Biological Age. Epigenetic clock https://i.ytimg.com/vi/uquZph42iSU/hqdefault.jpg Webinar by Steve Horvath on the epigenetic clock method from July 26, 2018. DNA methylation data have enabled accurate age estimates for any tissue across the entire life course. These 'epigenetic clocks' link developmental and maintenance processes to biological ageing, giving rise to a unified theory of life course. Citations a) Horvath (2013) DNA methylation age of human tissues and cell types. Genome Biology.PMID: 24138928 PMCID: PMC4015143 DOI: 10.1186/gb-2013-14-10-r115 https://www.ncbi.nlm.nih.gov/pubmed/24138928 b) Horvath and Raj (2018) DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nat Rev Genet. PMID: 29643443 DOI: 10.1038/s41576-018-0004-3 https://www.youtube-nocookie.com/embed/uquZph42iSU 4836 2018-07-27T19:57:44.000Z 2026-10-22T17:43:35.156Z https://longevityharbor.com/en/watch/urKZM7bkBy0 Video description: DNA methylation clocks and whether biological age can move both ways https://i.ytimg.com/vi/urKZM7bkBy0/hqdefault.jpg The description says biological age can differ from chronological age and be estimated from DNA methylation markers, and that research suggests it can move in both directions. It names lifestyle factors and cited studies but gives no results or numbers. https://www.youtube-nocookie.com/embed/urKZM7bkBy0 623 2026-05-27T10:30:26.000Z 2026-10-23T00:25:26.272Z https://longevityharbor.com/de/watch/urKZM7bkBy0 Videobeschreibung: DNA-Methylierungs-Uhren und ob biologisches Alter sich in beide Richtungen bewege https://i.ytimg.com/vi/urKZM7bkBy0/hqdefault.jpg Laut Beschreibung kann das biologische Alter vom chronologischen abweichen und über DNA-Methylierungsmarker geschätzt werden; Forschung deute darauf hin, dass es sich in beide Richtungen bewegen kann. Sie nennt Lebensstilfaktoren und zitierte Studien, aber keine Ergebnisse oder Zahlen. https://www.youtube-nocookie.com/embed/urKZM7bkBy0 623 2026-05-27T10:30:26.000Z 2026-10-23T00:25:26.272Z https://longevityharbor.com/en/watch/usS8rmgd-zU โปรตีนพิษ ต้นเหตุความจำเสื่อม https://i.ytimg.com/vi/usS8rmgd-zU/hqdefault.jpg Hallmarks of aging ตอนที่ 4 การเสียสมดุลการสร้างและการสลายโปรตีน ทำให้เกิดการสะสมโปรตีนพิษ Proteotoxic ในร่างกาย โดยเฉพาะในสมองและหัวใจ ต้นเหตุการเกิดโรคความจำเสื่อม #Longevity #Thelongevist #hallmarksofaging #ความจำเสื่อม https://www.youtube-nocookie.com/embed/usS8rmgd-zU 2378 2023-12-18T07:58:28.000Z 2026-10-22T19:54:19.435Z https://longevityharbor.com/de/watch/usS8rmgd-zU โปรตีนพิษ ต้นเหตุความจำเสื่อม https://i.ytimg.com/vi/usS8rmgd-zU/hqdefault.jpg Hallmarks of aging ตอนที่ 4 การเสียสมดุลการสร้างและการสลายโปรตีน ทำให้เกิดการสะสมโปรตีนพิษ Proteotoxic ในร่างกาย โดยเฉพาะในสมองและหัวใจ ต้นเหตุการเกิดโรคความจำเสื่อม #Longevity #Thelongevist #hallmarksofaging #ความจำเสื่อม https://www.youtube-nocookie.com/embed/usS8rmgd-zU 2378 2023-12-18T07:58:28.000Z 2026-10-22T19:54:19.435Z https://longevityharbor.com/en/watch/ut5ADc2eewE Knochen, Muskeln, Gelenke – so funktioniert der Stütz- und Bewegungsapparat https://i.ytimg.com/vi/ut5ADc2eewE/hqdefault.jpg Zum Stütz- und Bewegungsapparat gehören unter anderem das Skelett und die Skelettmuskulatur. Das Skelett besteht aus Knochen, die durch Gelenke beweglich miteinander verbunden sind. Vor allem die Gelenkform und stabilisierende Bänder bestimmen, in welche Richtungen verschiedene Körperteile bewegt werden können. Das Schultergelenk erlaubt beispielsweise mehr Richtungen als das Kniegelenk. Die meisten Bewegungen werden vom Gehirn gesteuert. Je komplexer die Bewegung wird, desto mehr Gelenke sind beteiligt und umso mehr Muskeln müssen in einer genauen Abfolge zusammenarbeiten. Dieses Zusammenspiel aus Knochen, Muskeln und Gelenken funktioniert so gut, dass wir nicht einmal darüber nachdenken müssen. Mehr dazu, wie der Stütz- und Bewegungsapparat funktioniert, können Sie auch auf dem Gesundheitsportal der Stiftung Gesundheitswissen nachlesen: https://www.stiftung-gesundheitswissen.de/gesundes-leben/koerper-wissen/knochen-gelenke-muskeln-wie-funktioniert-der-stuetz-und Dort finden Sie auch alle Angaben zu den Quellen, auf denen dieser Film beruht. #Bewegungsapparat #StiftungGesundheitswissen #Wissenistgesund https://www.youtube-nocookie.com/embed/ut5ADc2eewE 142 2022-07-28T06:15:20.000Z 2026-10-22T17:43:36.118Z https://longevityharbor.com/de/watch/ut5ADc2eewE Knochen, Muskeln, Gelenke – so funktioniert der Stütz- und Bewegungsapparat https://i.ytimg.com/vi/ut5ADc2eewE/hqdefault.jpg Zum Stütz- und Bewegungsapparat gehören unter anderem das Skelett und die Skelettmuskulatur. Das Skelett besteht aus Knochen, die durch Gelenke beweglich miteinander verbunden sind. Vor allem die Gelenkform und stabilisierende Bänder bestimmen, in welche Richtungen verschiedene Körperteile bewegt werden können. Das Schultergelenk erlaubt beispielsweise mehr Richtungen als das Kniegelenk. Die meisten Bewegungen werden vom Gehirn gesteuert. Je komplexer die Bewegung wird, desto mehr Gelenke sind beteiligt und umso mehr Muskeln müssen in einer genauen Abfolge zusammenarbeiten. Dieses Zusammenspiel aus Knochen, Muskeln und Gelenken funktioniert so gut, dass wir nicht einmal darüber nachdenken müssen. Mehr dazu, wie der Stütz- und Bewegungsapparat funktioniert, können Sie auch auf dem Gesundheitsportal der Stiftung Gesundheitswissen nachlesen: https://www.stiftung-gesundheitswissen.de/gesundes-leben/koerper-wissen/knochen-gelenke-muskeln-wie-funktioniert-der-stuetz-und Dort finden Sie auch alle Angaben zu den Quellen, auf denen dieser Film beruht. #Bewegungsapparat #StiftungGesundheitswissen #Wissenistgesund https://www.youtube-nocookie.com/embed/ut5ADc2eewE 142 2022-07-28T06:15:20.000Z 2026-10-22T17:43:36.118Z https://longevityharbor.com/en/watch/uvFb5rqczV4 The Hallmarks of Aging Ep 1 Introduction to Longevity and the Hallmarks of Aging https://i.ytimg.com/vi/uvFb5rqczV4/hqdefault.jpg The Hallmarks of Aging Ep 1 Introduction to Longevity and the Hallmarks of Aging "Welcome to the first episode of our series on longevity and the hallmarks of aging! Join Dr. Narinthorn Surasinthon as he introduces the concept of longevity, explores the nine hallmarks of aging, and explains why understanding these biological processes is key to living a longer, healthier life. Discover how scientific research and lifestyle choices can enhance your lifespan and healthspan. Don't forget to subscribe and stay tuned for more insights and practical tips on how to age well." The Longevist Clinic, Sukhumvit 36, Bangkok #longevity #hallmarksofaging #thelongevist . ติดตามช่องทางต่าง ๆ TIKTOK: https://www.tiktok.com/@thelongevist ปรึกษาหมอผ่าน LINE: lin.ee/XQzdB8h หรือ @Thelongevist Facebook: The Longevist https://www.youtube-nocookie.com/embed/uvFb5rqczV4 730 2024-07-25T04:08:26.000Z 2026-10-22T18:32:11.691Z https://longevityharbor.com/de/watch/uvFb5rqczV4 The Hallmarks of Aging Ep 1 Introduction to Longevity and the Hallmarks of Aging https://i.ytimg.com/vi/uvFb5rqczV4/hqdefault.jpg The Hallmarks of Aging Ep 1 Introduction to Longevity and the Hallmarks of Aging "Welcome to the first episode of our series on longevity and the hallmarks of aging! Join Dr. Narinthorn Surasinthon as he introduces the concept of longevity, explores the nine hallmarks of aging, and explains why understanding these biological processes is key to living a longer, healthier life. Discover how scientific research and lifestyle choices can enhance your lifespan and healthspan. Don't forget to subscribe and stay tuned for more insights and practical tips on how to age well." The Longevist Clinic, Sukhumvit 36, Bangkok #longevity #hallmarksofaging #thelongevist . ติดตามช่องทางต่าง ๆ TIKTOK: https://www.tiktok.com/@thelongevist ปรึกษาหมอผ่าน LINE: lin.ee/XQzdB8h หรือ @Thelongevist Facebook: The Longevist https://www.youtube-nocookie.com/embed/uvFb5rqczV4 730 2024-07-25T04:08:26.000Z 2026-10-22T18:32:11.691Z https://longevityharbor.com/en/watch/uxqQgancF3U Video description: circadian rhythms, light and biological age with Deanna Minich https://i.ytimg.com/vi/uxqQgancF3U/hqdefault.jpg The description says the episode covers light as a signal for the body's internal clock and discusses morning light, daytime brightness, evening darkness and nighttime habits, plus social jet lag and healthy aging. https://www.youtube-nocookie.com/embed/uxqQgancF3U 2501 2026-09-18T15:00:12.000Z 2026-10-22T22:04:54.498Z https://longevityharbor.com/de/watch/uxqQgancF3U Videobeschreibung: circadiane Rhythmen, Licht und biologisches Alter mit Deanna Minich https://i.ytimg.com/vi/uxqQgancF3U/hqdefault.jpg Laut Beschreibung behandelt die Episode Licht als Signal für die innere Uhr und bespricht Morgenlicht, Tageshelligkeit, Abenddunkelheit und Nachtgewohnheiten sowie sozialen Jetlag und gesundes Altern. https://www.youtube-nocookie.com/embed/uxqQgancF3U 2501 2026-09-18T15:00:12.000Z 2026-10-22T22:04:54.498Z https://longevityharbor.com/en/watch/uzG7Jwxf9v0 Panel on translating geroscience into FDA-satisfying aging trials https://i.ytimg.com/vi/uzG7Jwxf9v0/hqdefault.jpg A panel discusses how geroscience evidence from animals and growing human data could become an approved therapy, focusing on trial design, endpoints, regulation and funding. https://www.youtube-nocookie.com/embed/uzG7Jwxf9v0 2328 2026-08-20T22:28:56.000Z 2026-10-22T22:49:40.966Z https://longevityharbor.com/de/watch/uzG7Jwxf9v0 Podium zur Übersetzung der Gerowissenschaft in FDA-konforme Alterungstests https://i.ytimg.com/vi/uzG7Jwxf9v0/hqdefault.jpg Ein Podium erörtert, wie gerowissenschaftliche Belege aus Tiermodellen und wachsenden Humandaten zu einer zugelassenen Therapie werden könnten, mit Fokus auf Studiendesign, Endpunkte, Regulierung und Finanzierung. https://www.youtube-nocookie.com/embed/uzG7Jwxf9v0 2328 2026-08-20T22:28:56.000Z 2026-10-22T22:49:40.966Z https://longevityharbor.com/en/watch/v1pmy2XJYEU Video description: transplanted hearts and the recipient's biological age https://i.ytimg.com/vi/v1pmy2XJYEU/hqdefault.jpg The description says a new heart-transplant study found the recipient's body sets the transplanted organ's age, not the reverse, and it links further research on young and old organs. https://www.youtube-nocookie.com/embed/v1pmy2XJYEU 912 2026-10-02T11:58:58.000Z 2026-10-22T21:30:56.597Z https://longevityharbor.com/de/watch/v1pmy2XJYEU Videobeschreibung: transplantierte Herzen und das biologische Alter der Empfänger https://i.ytimg.com/vi/v1pmy2XJYEU/hqdefault.jpg Die Beschreibung berichtet, eine neue Herztransplantations-Studie habe ergeben, dass der Körper der Empfängerin oder des Empfängers das Alter des transplantierten Organs bestimmt und nicht umgekehrt; zudem verweist sie auf weitere Forschung zu jungen und alten Organen. https://www.youtube-nocookie.com/embed/v1pmy2XJYEU 912 2026-10-02T11:58:58.000Z 2026-10-22T21:30:56.597Z https://longevityharbor.com/en/watch/v4O1Pe2brEI Longevity specialist's description of her cellular-aging method for women after menopause https://i.ytimg.com/vi/v4O1Pe2brEI/hqdefault.jpg In this video description, longevity specialist Alejandra Garcia presents her five-pillar MIDAS Method for women after menopause; the description reports no study results. https://www.youtube-nocookie.com/embed/v4O1Pe2brEI 2577 2026-05-28T18:56:07.000Z 2026-10-23T00:18:54.694Z https://longevityharbor.com/de/watch/v4O1Pe2brEI Beschreibung der Zellalterungs-Methode einer Longevity-Spezialistin für Frauen nach der Menopause https://i.ytimg.com/vi/v4O1Pe2brEI/hqdefault.jpg In dieser Videobeschreibung stellt Longevity-Spezialistin Alejandra Garcia ihre fünfsäulige MIDAS-Methode für Frauen nach der Menopause vor; die Beschreibung berichtet keine Studienergebnisse. https://www.youtube-nocookie.com/embed/v4O1Pe2brEI 2577 2026-05-28T18:56:07.000Z 2026-10-23T00:18:54.694Z https://longevityharbor.com/en/watch/v5A5Qx0rxdQ Comparing aging clocks https://i.ytimg.com/vi/v5A5Qx0rxdQ/hqdefault.jpg Aging is a dynamic, non-linear process, but there is much hype around determining biomarkers for aging as this could help us understand what causes aging and assess the efficacy of anti-aging treatments. Watch the vid for more. Paper reference; https://doi.org/10.1016/j.arr.2020.101050 Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities https://www.youtube-nocookie.com/embed/v5A5Qx0rxdQ 834 2020-05-21T20:06:38.000Z 2026-10-22T17:43:44.500Z https://longevityharbor.com/de/watch/v5A5Qx0rxdQ Comparing aging clocks https://i.ytimg.com/vi/v5A5Qx0rxdQ/hqdefault.jpg Aging is a dynamic, non-linear process, but there is much hype around determining biomarkers for aging as this could help us understand what causes aging and assess the efficacy of anti-aging treatments. Watch the vid for more. Paper reference; https://doi.org/10.1016/j.arr.2020.101050 Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities https://www.youtube-nocookie.com/embed/v5A5Qx0rxdQ 834 2020-05-21T20:06:38.000Z 2026-10-22T17:43:44.500Z https://longevityharbor.com/en/watch/v6_nVjaiaqk Rapamycin in longevity research: a video description overview https://i.ytimg.com/vi/v6_nVjaiaqk/hqdefault.jpg The description says rapamycin is moving from transplant medicine into longevity research and presents a balanced look at risks, potential benefits and differing views between longevity clinics and primary care physicians. https://www.youtube-nocookie.com/embed/v6_nVjaiaqk 531 2026-08-28T15:00:13.000Z 2026-10-22T22:39:58.272Z https://longevityharbor.com/de/watch/v6_nVjaiaqk Rapamycin in der Langlebigkeitsforschung: ein Überblick der Videobeschreibung https://i.ytimg.com/vi/v6_nVjaiaqk/hqdefault.jpg Die Beschreibung sagt, Rapamycin wechsle von der Transplantationsmedizin in die Langlebigkeitsforschung, und verspricht einen ausgewogenen Blick auf Risiken, mögliche Nutzen und unterschiedliche Sichtweisen von Langlebigkeitskliniken und Hausärzten. https://www.youtube-nocookie.com/embed/v6_nVjaiaqk 531 2026-08-28T15:00:13.000Z 2026-10-22T22:39:58.272Z https://longevityharbor.com/en/watch/vDfqXtuNcPI Video description: circadian phasing and epigenetic rewriting linked to healthy aging https://i.ytimg.com/vi/vDfqXtuNcPI/hqdefault.jpg The description says the video examines how circadian phasing drives rewriting of the epigenome and discusses transcriptional plasticity in healthy aging and longevity. It gives no results, data or safety evidence. https://www.youtube-nocookie.com/embed/vDfqXtuNcPI 376 2026-04-21T01:23:30.000Z 2026-10-23T01:30:00.760Z https://longevityharbor.com/de/watch/vDfqXtuNcPI Videobeschreibung: zirkadiane Phasierung und epigenetisches Umschreiben mit gesundem Altern verknüpf https://i.ytimg.com/vi/vDfqXtuNcPI/hqdefault.jpg Laut Beschreibung untersucht das Video, wie zirkadiane Phasierung das Umschreiben des Epigenoms antreibt, und behandelt transkriptionelle Plastizität bei gesundem Altern und Langlebigkeit. Ergebnisse, Daten oder Sicherheitsbelege nennt sie nicht. https://www.youtube-nocookie.com/embed/vDfqXtuNcPI 376 2026-04-21T01:23:30.000Z 2026-10-23T01:30:00.760Z https://longevityharbor.com/en/watch/vEfqdNQMBnc Genetik und Epigenetik in der Langlebigkeit ❘ TECH Universität https://i.ytimg.com/vi/vEfqdNQMBnc/hqdefault.jpg 🔹In diesem Video erforschen wir, wie Genetik und Epigenetik den Alterungsprozess beeinflussen – von der Rolle der Telomere und der Telomerase bis hin zu epigenetischen Regulationsmechanismen, die die Zellreparatur und die Langlebigkeit bestimmen. Die Untersuchung der Telomerverkürzung, der Telomeraseaktivität und epigenetischer Modifikationen wie DNA-Methylierung oder MikroRNAs zeigt, wie unser Körper auf Umwelt- und Lebensstilfaktoren reagiert. Diese Prozesse bestimmen nicht nur die interne “biologische Uhr”, sondern auch die Anfälligkeit für chronische Krankheiten, die mit dem Altern verbunden sind. 🚀 Der Master in Ästhetischer Medizin an der TECH Universität integriert die neuesten Fortschritte in der Altersbiologie, der klinischen Epigenetik und den Präventionsstrategien und bietet Ärzten eine fundierte und praxisnahe Ausbildung zur Optimierung der Lebensqualität ihrer Patienten. 👉 Werden Sie ein Experte in ästhetischer und Anti-Aging-Medizin! https://tinyurl.com/bddtezas #techglobaluniversity #Epigenetik #ÄsthetischeMedizin 🗓️ 1 Jahr | ✅ 99 % Beschäftigungsfähigkeit | 🌐 100 % online Folgen Sie uns in unseren sozialen Netzwerken! 🎵 TikTok: https://www.tiktok.com/@techglobaleuniversyde 📸 Instagram: https://www.instagram.com/techglobaleuniversitat/ 📘 Facebook: https://www.facebook.com/TECHUniversitat/ 🌐 LinkedIn: https://www.linkedin.com/school/tech-universidad https://www.youtube-nocookie.com/embed/vEfqdNQMBnc 127 2025-09-05T13:01:50.000Z 2026-10-22T17:11:30.669Z https://longevityharbor.com/de/watch/vEfqdNQMBnc Genetik und Epigenetik in der Langlebigkeit ❘ TECH Universität https://i.ytimg.com/vi/vEfqdNQMBnc/hqdefault.jpg 🔹In diesem Video erforschen wir, wie Genetik und Epigenetik den Alterungsprozess beeinflussen – von der Rolle der Telomere und der Telomerase bis hin zu epigenetischen Regulationsmechanismen, die die Zellreparatur und die Langlebigkeit bestimmen. Die Untersuchung der Telomerverkürzung, der Telomeraseaktivität und epigenetischer Modifikationen wie DNA-Methylierung oder MikroRNAs zeigt, wie unser Körper auf Umwelt- und Lebensstilfaktoren reagiert. Diese Prozesse bestimmen nicht nur die interne “biologische Uhr”, sondern auch die Anfälligkeit für chronische Krankheiten, die mit dem Altern verbunden sind. 🚀 Der Master in Ästhetischer Medizin an der TECH Universität integriert die neuesten Fortschritte in der Altersbiologie, der klinischen Epigenetik und den Präventionsstrategien und bietet Ärzten eine fundierte und praxisnahe Ausbildung zur Optimierung der Lebensqualität ihrer Patienten. 👉 Werden Sie ein Experte in ästhetischer und Anti-Aging-Medizin! https://tinyurl.com/bddtezas #techglobaluniversity #Epigenetik #ÄsthetischeMedizin 🗓️ 1 Jahr | ✅ 99 % Beschäftigungsfähigkeit | 🌐 100 % online Folgen Sie uns in unseren sozialen Netzwerken! 🎵 TikTok: https://www.tiktok.com/@techglobaleuniversyde 📸 Instagram: https://www.instagram.com/techglobaleuniversitat/ 📘 Facebook: https://www.facebook.com/TECHUniversitat/ 🌐 LinkedIn: https://www.linkedin.com/school/tech-universidad https://www.youtube-nocookie.com/embed/vEfqdNQMBnc 127 2025-09-05T13:01:50.000Z 2026-10-22T17:11:30.669Z https://longevityharbor.com/en/watch/vGyFkLmRbAs Video description claims NMN supplements may revitalize cells and combat aging https://i.ytimg.com/vi/vGyFkLmRbAs/hqdefault.jpg The description says NAD+ science is about health and longevity and that NMN supplements can help revitalize cells and combat aging. It gives no study, dose or outcome data, and the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/vGyFkLmRbAs 125 2026-09-27T06:04:49.000Z 2026-10-22T21:43:49.601Z https://longevityharbor.com/de/watch/vGyFkLmRbAs Videobeschreibung behauptet, NMN-Präparate könnten Zellen beleben und Altern bekämpfen https://i.ytimg.com/vi/vGyFkLmRbAs/hqdefault.jpg Die Beschreibung sagt, NAD+-Wissenschaft betreffe Gesundheit und Langlebigkeit, und NMN-Präparate könnten helfen, Zellen zu beleben und das Altern zu bekämpfen. Sie nennt keine Studie, Dosis oder Ergebnisse; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/vGyFkLmRbAs 125 2026-09-27T06:04:49.000Z 2026-10-22T21:43:49.601Z https://longevityharbor.com/en/watch/vISuYDeCPEI How I Slowed My Ovarian Age (And How You Can Too) https://i.ytimg.com/vi/vISuYDeCPEI/hqdefault.jpg For the first time in history, ovarian biological age can be measured, and I became the first woman in the world to take the test. Until now, women have had no real way to understand how their ovaries are aging beyond rough estimates like AMH. But this new machine-learning algorithm, trained on over 40,000 real women across different life stages, analyzes hormone biomarkers, body composition, and reproductive history to estimate ovarian age relative to chronological age. This is a massive step forward in female longevity science. In this episode, I walk through what the test measures, how the algorithm works, and what becoming the first data point actually means, not just for me, but for women collectively. We also explore what may be driving ovarian aging in the first place. I also share how I’m now testing specific interventions in isolation, including hyperbaric oxygen therapy, to determine whether we can meaningfully influence ovarian aging over time. Ovarian lifespan is significantly shorter than overall lifespan and once we can measure it, we can begin to understand it. This is only the first step in redefining female longevity. See my full ovarian protocol here: https://www.protocol.kaylabarnes.com/#ovarian Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/female-longevity-community Chapters: 00:00:00 I Became the First Woman in the World to Test Her Ovarian Age 00:02:25 Why Ovarian Age Matters More Than AMH Alone 00:04:03 My Full Longevity Protocol Recap 00:05:01 Why I’m Isolating Hyperbaric Oxygen 00:07:07 The Hallmarks of Ovarian Aging: A New Framework 00:07:23 Hallmark #1: Mitochondrial Dysfunction 00: https://www.youtube-nocookie.com/embed/vISuYDeCPEI 1126 2026-02-14T10:01:25.000Z 2026-10-22T19:54:19.184Z https://longevityharbor.com/de/watch/vISuYDeCPEI How I Slowed My Ovarian Age (And How You Can Too) https://i.ytimg.com/vi/vISuYDeCPEI/hqdefault.jpg For the first time in history, ovarian biological age can be measured, and I became the first woman in the world to take the test. Until now, women have had no real way to understand how their ovaries are aging beyond rough estimates like AMH. But this new machine-learning algorithm, trained on over 40,000 real women across different life stages, analyzes hormone biomarkers, body composition, and reproductive history to estimate ovarian age relative to chronological age. This is a massive step forward in female longevity science. In this episode, I walk through what the test measures, how the algorithm works, and what becoming the first data point actually means, not just for me, but for women collectively. We also explore what may be driving ovarian aging in the first place. I also share how I’m now testing specific interventions in isolation, including hyperbaric oxygen therapy, to determine whether we can meaningfully influence ovarian aging over time. Ovarian lifespan is significantly shorter than overall lifespan and once we can measure it, we can begin to understand it. This is only the first step in redefining female longevity. See my full ovarian protocol here: https://www.protocol.kaylabarnes.com/#ovarian Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/female-longevity-community Chapters: 00:00:00 I Became the First Woman in the World to Test Her Ovarian Age 00:02:25 Why Ovarian Age Matters More Than AMH Alone 00:04:03 My Full Longevity Protocol Recap 00:05:01 Why I’m Isolating Hyperbaric Oxygen 00:07:07 The Hallmarks of Ovarian Aging: A New Framework 00:07:23 Hallmark #1: Mitochondrial Dysfunction 00: https://www.youtube-nocookie.com/embed/vISuYDeCPEI 1126 2026-02-14T10:01:25.000Z 2026-10-22T19:54:19.184Z https://longevityharbor.com/en/watch/vKjqIWwCXA8 Astaxanthin and Aging Muscle: What a Video Description Says the Research Shows https://i.ytimg.com/vi/vKjqIWwCXA8/hqdefault.jpg A video description says astaxanthin from microalgae acts inside cells and may support muscle endurance, strength and blood vessel flexibility in older adults. It names several studies but gives no results, numbers or study details, so no benefit can be judged from it. https://www.youtube-nocookie.com/embed/vKjqIWwCXA8 707 2026-10-22T10:25:49.000Z 2026-10-22T19:45:33.678Z https://longevityharbor.com/de/watch/vKjqIWwCXA8 Astaxanthin und alternde Muskeln: Was eine Videobeschreibung zur Forschung sagt https://i.ytimg.com/vi/vKjqIWwCXA8/hqdefault.jpg Eine Videobeschreibung sagt, Astaxanthin aus Mikroalgen wirke in Zellen und könne bei älteren Erwachsenen Muskelausdauer, Kraft und Gefäßflexibilität unterstützen. Sie nennt mehrere Studien, aber keine Ergebnisse, Zahlen oder Studiendetails; ein Nutzen lässt sich daraus nicht beurteilen. https://www.youtube-nocookie.com/embed/vKjqIWwCXA8 707 2026-10-22T10:25:49.000Z 2026-10-22T19:45:33.678Z https://longevityharbor.com/en/watch/vPcIgfKWG-I Epitalon for sleep and circadian rhythm: claims versus evidence https://i.ytimg.com/vi/vPcIgfKWG-I/hqdefault.jpg The description says Epitalon is a synthetic tetrapeptide studied in laboratory and limited human research; claims about melatonin, circadian rhythm, telomeres, recovery and longevity remain investigational, and the creator shares personal sleep experience, not medical advice. https://www.youtube-nocookie.com/embed/vPcIgfKWG-I 103 2026-08-26T14:17:19.000Z 2026-10-22T22:42:15.787Z https://longevityharbor.com/de/watch/vPcIgfKWG-I Epitalon für Schlaf und circadianen Rhythmus: Behauptungen und Belege https://i.ytimg.com/vi/vPcIgfKWG-I/hqdefault.jpg Laut Beschreibung ist Epitalon ein synthetisches Tetrapeptid, das in Labor- und begrenzter Humanforschung untersucht wurde; Aussagen zu Melatonin, circadianem Rhythmus, Telomeren, Erholung und Langlebigkeit bleiben investigativ, und der Ersteller schildert persönliche Schlaf-Erfahrungen, keine medizinische Beratung. https://www.youtube-nocookie.com/embed/vPcIgfKWG-I 103 2026-08-26T14:17:19.000Z 2026-10-22T22:42:15.787Z https://longevityharbor.com/en/watch/vT0jQMiL6fk Lecture description: mTOR, brain aging after 40 and blood or CSF markers https://i.ytimg.com/vi/vT0jQMiL6fk/hqdefault.jpg The description says the lecture covers evidence that excessive mTOR pathway activation from dietary branched chain amino acids may harm the brain, that brain function declines progressively after age 40 alongside gray matter and synapse reductions, and that molecular markers of brain aging are being identified in blood and cerebrospinal fluid. https://www.youtube-nocookie.com/embed/vT0jQMiL6fk 4749 2025-12-10T18:23:11.000Z 2026-10-23T03:17:15.361Z https://longevityharbor.com/de/watch/vT0jQMiL6fk Vortragsbeschreibung: mTOR, Gehirnalterung ab 40 und Marker in Blut oder Nervenwasser https://i.ytimg.com/vi/vT0jQMiL6fk/hqdefault.jpg Laut Beschreibung behandelt der Vortrag Hinweise, dass eine übermäßige mTOR-Aktivierung durch verzweigtkettige Aminosäuren in der Nahrung dem Gehirn schaden kann, dass die Gehirnfunktion ab 40 Jahren fortschreitend abnimmt und dabei graue Substanz und Synapsen abnehmen, und dass molekulare Marker der Gehirnalterung in Blut und Nervenwasser identifiziert werden. https://www.youtube-nocookie.com/embed/vT0jQMiL6fk 4749 2025-12-10T18:23:11.000Z 2026-10-23T03:17:15.361Z https://longevityharbor.com/en/watch/vTyjiuOQ8I8 The Effects of Cellular Senescence and Senolytics on Healthspan with Dr. James Kirkland https://i.ytimg.com/vi/vTyjiuOQ8I8/hqdefault.jpg Do you know what senescent (zombie) cells are and how cellular senescence and senolytics impact health? In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander are joined by Dr. James Kirkland from the Mayo Clinic, one of the world's leading figures in aging research. This episode is a deep dive into aging research, cellular senescence, and senolytics. Dr. Kirkland discusses the impact of cellular aging (senescence) on healthspan and his discovery of the first senolytic agents that remove senescent cells and extend healthspan, illuminating his pioneering work in aging research. Dr. Kirkland shares insights into the science of cellular senescence and how targeting these cells could revolutionize the treatment of age-related chronic diseases. He sheds light on the mechanisms behind senolytics and their promise for extending healthspan. The discussion also touches on the importance of lifestyle factors like diet and exercise in managing senescent cells. Dr. Kirkland also discusses geroscience, a research paradigm that seeks to understand the mechanisms that make aging a major risk factor for and driver of common chronic conditions and diseases of older people. This knowledge can be used to slow the rate of aging, reverse its effects, delay or even cure age-related diseases, and extend healthspan. The conversation also highlights the emerging evidence and potential of using gerotherapeutics (treatments) that target aging biology to combat aging-related diseases and increase healthspan and lifespan. Dr. Kirkland also covers the challenges and opportunities in translating these scientific discoveries into clinical applications, emphasizing the critical role of interdisciplinary efforts in advancing our understanding and management of aging. This is an enlightening episode with Dr. Kirkland on aging research and the opportunities to revolutionize healthcare by combating aging-related diseases and increasing people’s healthspan and lifespan. Introduction: 00:00-03:49 What led Dr. James Kirkla https://www.youtube-nocookie.com/embed/vTyjiuOQ8I8 4334 2024-04-17T17:00:37.000Z 2026-10-22T18:43:13.556Z https://longevityharbor.com/de/watch/vTyjiuOQ8I8 The Effects of Cellular Senescence and Senolytics on Healthspan with Dr. James Kirkland https://i.ytimg.com/vi/vTyjiuOQ8I8/hqdefault.jpg Do you know what senescent (zombie) cells are and how cellular senescence and senolytics impact health? In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander are joined by Dr. James Kirkland from the Mayo Clinic, one of the world's leading figures in aging research. This episode is a deep dive into aging research, cellular senescence, and senolytics. Dr. Kirkland discusses the impact of cellular aging (senescence) on healthspan and his discovery of the first senolytic agents that remove senescent cells and extend healthspan, illuminating his pioneering work in aging research. Dr. Kirkland shares insights into the science of cellular senescence and how targeting these cells could revolutionize the treatment of age-related chronic diseases. He sheds light on the mechanisms behind senolytics and their promise for extending healthspan. The discussion also touches on the importance of lifestyle factors like diet and exercise in managing senescent cells. Dr. Kirkland also discusses geroscience, a research paradigm that seeks to understand the mechanisms that make aging a major risk factor for and driver of common chronic conditions and diseases of older people. This knowledge can be used to slow the rate of aging, reverse its effects, delay or even cure age-related diseases, and extend healthspan. The conversation also highlights the emerging evidence and potential of using gerotherapeutics (treatments) that target aging biology to combat aging-related diseases and increase healthspan and lifespan. Dr. Kirkland also covers the challenges and opportunities in translating these scientific discoveries into clinical applications, emphasizing the critical role of interdisciplinary efforts in advancing our understanding and management of aging. This is an enlightening episode with Dr. Kirkland on aging research and the opportunities to revolutionize healthcare by combating aging-related diseases and increasing people’s healthspan and lifespan. Introduction: 00:00-03:49 What led Dr. James Kirkla https://www.youtube-nocookie.com/embed/vTyjiuOQ8I8 4334 2024-04-17T17:00:37.000Z 2026-10-22T18:43:13.556Z https://longevityharbor.com/en/watch/vV4wsBB36hA NAD⁺ and aging: what NR, NMN and infusions actually show https://i.ytimg.com/vi/vV4wsBB36hA/hqdefault.jpg A pharmacist's video description separates NAD⁺ biology from anti-aging promises: human studies show NAD⁺ precursors can influence NAD⁺ metabolism, but relevant health benefits or slowed human aging are not sufficiently proven. https://www.youtube-nocookie.com/embed/vV4wsBB36hA 812 2026-09-06T07:09:05.000Z 2026-10-22T22:28:11.141Z https://longevityharbor.com/de/watch/vV4wsBB36hA NAD⁺ und Altern: Was NR, NMN und Infusionen wirklich zeigen https://i.ytimg.com/vi/vV4wsBB36hA/hqdefault.jpg Die Beschreibung eines Apothekerinnen-Videos trennt NAD⁺-Biologie von Anti-Aging-Versprechen: Humanstudien zeigen, dass NAD⁺-Vorstufen den NAD⁺-Stoffwechsel beeinflussen können, doch relevante Gesundheitsvorteile oder eine Verlangsamung des menschlichen Alterns sind nicht ausreichend belegt. https://www.youtube-nocookie.com/embed/vV4wsBB36hA 812 2026-09-06T07:09:05.000Z 2026-10-22T22:28:11.141Z https://longevityharbor.com/en/watch/vV5R3lW2_Zc NMN or NAD? Here are my thoughts! #nad #nmn #antiaging #tiktokshopcreatorpicks #tiktokshopstockup https://i.ytimg.com/vi/vV5R3lW2_Zc/hqdefault.jpg NMN or NAD? Here are my thoughts! #nad #nmn #antiaging #tiktokshopcreatorpicks #tiktokshopstockup https://www.youtube-nocookie.com/embed/vV5R3lW2_Zc 156 2026-09-04T21:08:24.000Z 2026-10-22T17:43:42.553Z https://longevityharbor.com/de/watch/vV5R3lW2_Zc NMN or NAD? Here are my thoughts! #nad #nmn #antiaging #tiktokshopcreatorpicks #tiktokshopstockup https://i.ytimg.com/vi/vV5R3lW2_Zc/hqdefault.jpg NMN or NAD? Here are my thoughts! #nad #nmn #antiaging #tiktokshopcreatorpicks #tiktokshopstockup https://www.youtube-nocookie.com/embed/vV5R3lW2_Zc 156 2026-09-04T21:08:24.000Z 2026-10-22T17:43:42.553Z https://longevityharbor.com/en/watch/vWrzH4IBs-Q Growing MUSCLES over 50 Years of Age https://i.ytimg.com/vi/vWrzH4IBs-Q/hqdefault.jpg Did you know that weight loss can sometimes shorten your lifespan? But how can that be? In this video, we’ll talk about muscle mass and longevity and preserving muscle as you age. Not all weight loss is good weight loss! Just so you know, my full line of high-quality supplements is available on Amazon — search Dr. Berg Supplements. How to Fix Your Gut: ▶️ https://youtu.be/nZV1oYv5Ddo How to Make L. Reuteri Yogurt: https://drbrg.co/42YvAUg [Affiliate links] Yogurt Maker: https://drbrg.co/yogurt-maker2 Yogurt Jars: https://drbrg.co/yogurtjars Yogurt Containers: https://drbrg.co/yogurt-containers Organic Inulin: https://drbrg.co/organicinulin 0:00 Introduction: How to prevent muscle loss 0:22 Ozempic for weight loss 1:25 Sarcopenia 1:56 How to avoid age-related muscle loss 3:07 Sleep and muscle recovery 4:47 The muscle reserve 5:23 Other types of muscle loss 5:36 Top anti-aging tips 7:22 The #1 anti-aging secret! Losing weight should help you live longer, but it’s not always that simple. As you age, it’s vital to maintain a healthy amount of lean muscle mass. Ozempic is very popular for weight loss, but trials have shown that it can cause muscle loss, not just fat loss. One study compared the use of Ozempic to a decade or more of aging. Preserving muscle mass is one of the best things you can do for longevity. Your muscles help regulate your blood sugar and support your metabolism. Sarcopenia is the term for age-related muscle loss. When you develop sarcopenia, your risk for diabetes, immune problems, and your mortality rate increases. Exercise is the best thing you can do for your muscles. Protein is the raw material for muscle-building, so it’s essential to ensure you’re getting enough and spreading your intake throughout the day. Grass-fed red meat is the best source of protein. Poor sleep drains muscle mass more than poor diet because muscle recovery occurs when you’re sleeping. In summary, focus on the following as you age: •Increase lean muscle mass •Ensure adequate protein intake •Consum https://www.youtube-nocookie.com/embed/vWrzH4IBs-Q 482 2025-01-10T11:30:39.000Z 2026-10-22T18:32:08.299Z https://longevityharbor.com/de/watch/vWrzH4IBs-Q Growing MUSCLES over 50 Years of Age https://i.ytimg.com/vi/vWrzH4IBs-Q/hqdefault.jpg Did you know that weight loss can sometimes shorten your lifespan? But how can that be? In this video, we’ll talk about muscle mass and longevity and preserving muscle as you age. Not all weight loss is good weight loss! Just so you know, my full line of high-quality supplements is available on Amazon — search Dr. Berg Supplements. How to Fix Your Gut: ▶️ https://youtu.be/nZV1oYv5Ddo How to Make L. Reuteri Yogurt: https://drbrg.co/42YvAUg [Affiliate links] Yogurt Maker: https://drbrg.co/yogurt-maker2 Yogurt Jars: https://drbrg.co/yogurtjars Yogurt Containers: https://drbrg.co/yogurt-containers Organic Inulin: https://drbrg.co/organicinulin 0:00 Introduction: How to prevent muscle loss 0:22 Ozempic for weight loss 1:25 Sarcopenia 1:56 How to avoid age-related muscle loss 3:07 Sleep and muscle recovery 4:47 The muscle reserve 5:23 Other types of muscle loss 5:36 Top anti-aging tips 7:22 The #1 anti-aging secret! Losing weight should help you live longer, but it’s not always that simple. As you age, it’s vital to maintain a healthy amount of lean muscle mass. Ozempic is very popular for weight loss, but trials have shown that it can cause muscle loss, not just fat loss. One study compared the use of Ozempic to a decade or more of aging. Preserving muscle mass is one of the best things you can do for longevity. Your muscles help regulate your blood sugar and support your metabolism. Sarcopenia is the term for age-related muscle loss. When you develop sarcopenia, your risk for diabetes, immune problems, and your mortality rate increases. Exercise is the best thing you can do for your muscles. Protein is the raw material for muscle-building, so it’s essential to ensure you’re getting enough and spreading your intake throughout the day. Grass-fed red meat is the best source of protein. Poor sleep drains muscle mass more than poor diet because muscle recovery occurs when you’re sleeping. In summary, focus on the following as you age: •Increase lean muscle mass •Ensure adequate protein intake •Consum https://www.youtube-nocookie.com/embed/vWrzH4IBs-Q 482 2025-01-10T11:30:39.000Z 2026-10-22T18:32:08.299Z https://longevityharbor.com/en/watch/vg0CS12k_2Q Episode 2 - the Hallmarks of Ageing https://i.ytimg.com/vi/vg0CS12k_2Q/hqdefault.jpg Hallmarks of Ageing - Episode 2 in my video series 'Stop Ageing'. https://www.youtube-nocookie.com/embed/vg0CS12k_2Q 149 2024-12-02T21:47:30.000Z 2026-10-22T19:04:38.594Z https://longevityharbor.com/de/watch/vg0CS12k_2Q Episode 2 - the Hallmarks of Ageing https://i.ytimg.com/vi/vg0CS12k_2Q/hqdefault.jpg Hallmarks of Ageing - Episode 2 in my video series 'Stop Ageing'. https://www.youtube-nocookie.com/embed/vg0CS12k_2Q 149 2024-12-02T21:47:30.000Z 2026-10-22T19:04:38.594Z https://longevityharbor.com/en/watch/vhTqXUnRn5Y 🌟 Zombie Cell Killers New Hope for Aging Bones! 🌟 https://i.ytimg.com/vi/vhTqXUnRn5Y/hqdefault.jpg 🌟 Zombie Cell Killers: New Hope for Aging Bones! 🌟 🔬 Revolutionizing Anti-Aging Treatments with Senolytic Drugs 🔬 🌱 Mayo Clinic Study Reveals Promising Results for Bone Health 🌱 Join us as we explore groundbreaking research from the Mayo Clinic that shows how senolytic drugs, particularly a combination of dasatinib and quercetin, can enhance bone health in older women with high senescent cell counts. Learn about the importance of tailored treatments and the potential benefits of targeting "zombie cells" to reduce age-related health issues. Discover the future of anti-aging treatments and the broader implications for disease treatment. Don't miss this exciting development in the field of aging and bone health! 🌟 #MayoClinic #Aging #BoneHealth #SenolyticDrugs #AntiAging #Health #Research #Science #Medicine #Healthcare📚 Interested in learning more? Check out these amazing science books and resources on Amazon that I've handpicked for you! Dive deeper into the subject and expand your knowledge. 📚 🛍️ Shop my recommendations: https://amzn.to/3AuBl1r 💡 Remember, when you purchase through my link, you're supporting my channel and helping me create more engaging science content for you! It doesn't cost you anything extra, but it means a lot to me. 😊 ⬇️ Don't forget to: Like this video if you enjoyed it! Subscribe for more bite-sized science content! #ScienceInAMinute #LearnWithMe #AmazonFinds https://www.youtube-nocookie.com/embed/vhTqXUnRn5Y 1122 2024-11-01T08:12:06.000Z 2026-10-22T19:43:47.758Z https://longevityharbor.com/de/watch/vhTqXUnRn5Y 🌟 Zombie Cell Killers New Hope for Aging Bones! 🌟 https://i.ytimg.com/vi/vhTqXUnRn5Y/hqdefault.jpg 🌟 Zombie Cell Killers: New Hope for Aging Bones! 🌟 🔬 Revolutionizing Anti-Aging Treatments with Senolytic Drugs 🔬 🌱 Mayo Clinic Study Reveals Promising Results for Bone Health 🌱 Join us as we explore groundbreaking research from the Mayo Clinic that shows how senolytic drugs, particularly a combination of dasatinib and quercetin, can enhance bone health in older women with high senescent cell counts. Learn about the importance of tailored treatments and the potential benefits of targeting "zombie cells" to reduce age-related health issues. Discover the future of anti-aging treatments and the broader implications for disease treatment. Don't miss this exciting development in the field of aging and bone health! 🌟 #MayoClinic #Aging #BoneHealth #SenolyticDrugs #AntiAging #Health #Research #Science #Medicine #Healthcare📚 Interested in learning more? Check out these amazing science books and resources on Amazon that I've handpicked for you! Dive deeper into the subject and expand your knowledge. 📚 🛍️ Shop my recommendations: https://amzn.to/3AuBl1r 💡 Remember, when you purchase through my link, you're supporting my channel and helping me create more engaging science content for you! It doesn't cost you anything extra, but it means a lot to me. 😊 ⬇️ Don't forget to: Like this video if you enjoyed it! Subscribe for more bite-sized science content! #ScienceInAMinute #LearnWithMe #AmazonFinds https://www.youtube-nocookie.com/embed/vhTqXUnRn5Y 1122 2024-11-01T08:12:06.000Z 2026-10-22T19:43:47.758Z https://longevityharbor.com/en/watch/vjT6Tgc-1e4 Young Goose founders discuss skin longevity, exosomes and red light in a video description https://i.ytimg.com/vi/vjT6Tgc-1e4/hqdefault.jpg In the supplied description, the Young Goose co-founders and host Dave Asprey discuss cellular skin aging, ingredients such as methylene blue and NAD+ precursors, platelet-derived exosomes and red light therapy. The description reports topics discussed, not tested outcomes. https://www.youtube-nocookie.com/embed/vjT6Tgc-1e4 3035 2026-10-01T20:03:36.000Z 2026-10-22T21:31:32.921Z https://longevityharbor.com/de/watch/vjT6Tgc-1e4 Young-Goose-Gründer sprechen in einer Videobeschreibung über Haut-Longevity, Exosomen und Rotlicht https://i.ytimg.com/vi/vjT6Tgc-1e4/hqdefault.jpg In der vorliegenden Beschreibung erörtern die Young-Goose-Mitgründer und Gastgeber Dave Asprey zelluläre Hautalterung, Inhaltsstoffe wie Methylenblau und NAD+-Vorstufen, aus Blutplättchen gewonnene Exosomen und Rotlichttherapie. Die Beschreibung nennt besprochene Themen, keine geprüften Ergebnisse. https://www.youtube-nocookie.com/embed/vjT6Tgc-1e4 3035 2026-10-01T20:03:36.000Z 2026-10-22T21:31:32.921Z https://longevityharbor.com/en/watch/vnetuCPQ9S8 How Rapamycin/metformin As Rejuvinating Drug? https://i.ytimg.com/vi/vnetuCPQ9S8/hqdefault.jpg Rapamycin is a naturally occurring compound found in the bacterium Streptomyces hygroscopicus. It has been widely used in medicine and research due to its unique properties and effects on various cellular processes. Rapamycin's main uses and effects include: 1. Immunosuppression: Rapamycin is used to prevent organ rejection in transplant patients by suppressing the immune system. 2. Anti-cancer properties: Rapamycin has been shown to inhibit tumor growth and induce apoptosis (cell death) in cancer cells. 3. Anti-aging research: Rapamycin has been studied for its potential to extend lifespan and improve age-related health issues, as it activates cellular pathways that promote longevity. 4. Autophagy induction: Rapamycin stimulates autophagy, a natural process in which cells recycle damaged or dysfunctional components. 5. mTOR inhibition: Rapamycin inhibits the mechanistic target of rapamycin (mTOR) pathway, which regulates cell growth, metabolism, and protein synthesis. Research on rapamycin continues to explore its potential applications in various fields, including: 1. Neurodegenerative diseases (e.g., Alzheimer's, Parkinson's) 2. Metabolic disorders (e.g., diabetes, obesity) 3. Cardiovascular disease 4. Regenerative medicine Please consult a healthcare professional for medical advice or treatment. Metformin, a medication typically used to treat type 2 diabetes, has been studied for its potential anti-aging effects. Research suggests that metformin may: 1. Improve insulin sensitivity and glucose metabolism 2. Reduce oxidative stress and inflammation 3. Activate cellular pathways that promote longevity (e.g., AMPK, SIRT1) 4. Inhibit cellular senescence and aging 5. Enhance autophagy, a natural cellular recycling process Some potential anti-aging benefits of metformin include: 1. Improved cardiovascular health 2. Enhanced cognitive function and neuroprotection 3. Reduced cancer risk 4. Improved immune function 5. Increased lifespan (in animal studies) However, it's important to note that: 1. Human tria https://www.youtube-nocookie.com/embed/vnetuCPQ9S8 277 2024-04-30T08:52:25.000Z 2026-10-22T19:32:35.521Z https://longevityharbor.com/de/watch/vnetuCPQ9S8 How Rapamycin/metformin As Rejuvinating Drug? https://i.ytimg.com/vi/vnetuCPQ9S8/hqdefault.jpg Rapamycin is a naturally occurring compound found in the bacterium Streptomyces hygroscopicus. It has been widely used in medicine and research due to its unique properties and effects on various cellular processes. Rapamycin's main uses and effects include: 1. Immunosuppression: Rapamycin is used to prevent organ rejection in transplant patients by suppressing the immune system. 2. Anti-cancer properties: Rapamycin has been shown to inhibit tumor growth and induce apoptosis (cell death) in cancer cells. 3. Anti-aging research: Rapamycin has been studied for its potential to extend lifespan and improve age-related health issues, as it activates cellular pathways that promote longevity. 4. Autophagy induction: Rapamycin stimulates autophagy, a natural process in which cells recycle damaged or dysfunctional components. 5. mTOR inhibition: Rapamycin inhibits the mechanistic target of rapamycin (mTOR) pathway, which regulates cell growth, metabolism, and protein synthesis. Research on rapamycin continues to explore its potential applications in various fields, including: 1. Neurodegenerative diseases (e.g., Alzheimer's, Parkinson's) 2. Metabolic disorders (e.g., diabetes, obesity) 3. Cardiovascular disease 4. Regenerative medicine Please consult a healthcare professional for medical advice or treatment. Metformin, a medication typically used to treat type 2 diabetes, has been studied for its potential anti-aging effects. Research suggests that metformin may: 1. Improve insulin sensitivity and glucose metabolism 2. Reduce oxidative stress and inflammation 3. Activate cellular pathways that promote longevity (e.g., AMPK, SIRT1) 4. Inhibit cellular senescence and aging 5. Enhance autophagy, a natural cellular recycling process Some potential anti-aging benefits of metformin include: 1. Improved cardiovascular health 2. Enhanced cognitive function and neuroprotection 3. Reduced cancer risk 4. Improved immune function 5. Increased lifespan (in animal studies) However, it's important to note that: 1. Human tria https://www.youtube-nocookie.com/embed/vnetuCPQ9S8 277 2024-04-30T08:52:25.000Z 2026-10-22T19:32:35.521Z https://longevityharbor.com/en/watch/vqHkP4oHQ7g Circadian Rhythm – The Ancient Clock of Rejuvenation https://i.ytimg.com/vi/vqHkP4oHQ7g/hqdefault.jpg In this episode, discover the hidden power of your circadian rhythm — your body’s ancient biological clock that governs sleep, energy, mood, and longevity. Learn how aligning your daily habits with nature’s light and dark cycles can reverse fatigue, slow aging, and awaken cellular rejuvenation. You’ll learn how to: • Reset your body’s natural clock for deeper sleep and higher energy • Use morning sunlight to reprogram your hormones naturally • Eat and rest in sync with your internal rhythm for faster cellular repair • Avoid common habits that silently accelerate aging • Unlock the genetic keys that make your body biologically younger This isn’t just about sleep — it’s about returning to your natural timing, where your mind, body, and spirit move in harmony with life itself. ✨ Stay till the end for a guided reflection to help you reconnect with your body’s ancient rhythm of rejuvenation. 🎧 Subscribe to Ageless Secrets for more episodes on longevity, healing, and the true science of ageless living. #AgelessSecrets #CircadianRhythm #Longevity #ReverseAging #SleepScience #NaturalHealing #WellnessJourney #Biohacking #HealthyHabits #MindBodyBalance https://www.youtube-nocookie.com/embed/vqHkP4oHQ7g 544 2025-10-26T01:38:38.000Z 2026-10-22T19:21:25.233Z https://longevityharbor.com/de/watch/vqHkP4oHQ7g Circadian Rhythm – The Ancient Clock of Rejuvenation https://i.ytimg.com/vi/vqHkP4oHQ7g/hqdefault.jpg In this episode, discover the hidden power of your circadian rhythm — your body’s ancient biological clock that governs sleep, energy, mood, and longevity. Learn how aligning your daily habits with nature’s light and dark cycles can reverse fatigue, slow aging, and awaken cellular rejuvenation. You’ll learn how to: • Reset your body’s natural clock for deeper sleep and higher energy • Use morning sunlight to reprogram your hormones naturally • Eat and rest in sync with your internal rhythm for faster cellular repair • Avoid common habits that silently accelerate aging • Unlock the genetic keys that make your body biologically younger This isn’t just about sleep — it’s about returning to your natural timing, where your mind, body, and spirit move in harmony with life itself. ✨ Stay till the end for a guided reflection to help you reconnect with your body’s ancient rhythm of rejuvenation. 🎧 Subscribe to Ageless Secrets for more episodes on longevity, healing, and the true science of ageless living. #AgelessSecrets #CircadianRhythm #Longevity #ReverseAging #SleepScience #NaturalHealing #WellnessJourney #Biohacking #HealthyHabits #MindBodyBalance https://www.youtube-nocookie.com/embed/vqHkP4oHQ7g 544 2025-10-26T01:38:38.000Z 2026-10-22T19:21:25.233Z https://longevityharbor.com/en/watch/vsNhfGI4jYA Biomarkers of aging: How close are we, really? - A conversation with Sara Hägg https://i.ytimg.com/vi/vsNhfGI4jYA/hqdefault.jpg Sara Hägg, PhD is an associate professor at Karolinska Institutet, where she leads the Molecular Epidemiology of Aging Group. Her work focuses on human biomarkers of aging - especially biological age “clocks” built from epigenetic, proteomic, and metabolomic data - and on turning Nordic registry resources into clinically useful aging measures. In this episode you'll learn more about: * What biological/epigenetic age clocks actually measure (and what they don’t) * Accuracy, error bars, and why clocks aren’t clinic-ready yet * Epigenetic vs. proteomic vs. metabolomic clocks - strengths and trade-offs * Organ-specific clocks (liver, ovary, kidney) and what they reveal * Why uncertainty spikes at life transitions; menopause as a natural “stress test” * PC (principal-component) clocks and noise reduction * Nordic registry & Swedish Twin Registry advantages; UK Biobank use * Direct-to-consumer tests: interpreting results and common pitfalls * AI’s role in building/validating clocks and handling uncertainty * What would move the field fastest (data, standards, trials) and where Sweden stands ---- 👋🏼 Want to show your support? Subscribe to our channel, hit the notification bell and/or send us a Super Thanks! 👋🏼👋🏼👋🏼 Want to show your support and get some extra perks? Become a member! https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA/join Show notes for this episode will be available after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: reachlevity.com LEVITY is co-hosted by Patrick Linden, philosopher and author, and Peter Ottsjö, journalist and author. ----- CHAPTERS 00:00 Introduction 03:27 Why Sweden lags behind in longevity science 08:04 Nordic registry & Swedish twin registry advantages; UK Biobank use 10:05 What is biological age? 16:33 The rise of epigenetic clocks 24:22 The importance of aging clocks 32:04 Beyond methylation: proteomic and metabolomic clocks 35:12 Organ clocks 39:37 Do aging clocks generalize? 54:37 The cost of aging clocks 01:03:18 Uncertain https://www.youtube-nocookie.com/embed/vsNhfGI4jYA 5783 2025-10-28T17:01:40.000Z 2026-10-22T19:32:34.499Z https://longevityharbor.com/de/watch/vsNhfGI4jYA Biomarkers of aging: How close are we, really? - A conversation with Sara Hägg https://i.ytimg.com/vi/vsNhfGI4jYA/hqdefault.jpg Sara Hägg, PhD is an associate professor at Karolinska Institutet, where she leads the Molecular Epidemiology of Aging Group. Her work focuses on human biomarkers of aging - especially biological age “clocks” built from epigenetic, proteomic, and metabolomic data - and on turning Nordic registry resources into clinically useful aging measures. In this episode you'll learn more about: * What biological/epigenetic age clocks actually measure (and what they don’t) * Accuracy, error bars, and why clocks aren’t clinic-ready yet * Epigenetic vs. proteomic vs. metabolomic clocks - strengths and trade-offs * Organ-specific clocks (liver, ovary, kidney) and what they reveal * Why uncertainty spikes at life transitions; menopause as a natural “stress test” * PC (principal-component) clocks and noise reduction * Nordic registry & Swedish Twin Registry advantages; UK Biobank use * Direct-to-consumer tests: interpreting results and common pitfalls * AI’s role in building/validating clocks and handling uncertainty * What would move the field fastest (data, standards, trials) and where Sweden stands ---- 👋🏼 Want to show your support? Subscribe to our channel, hit the notification bell and/or send us a Super Thanks! 👋🏼👋🏼👋🏼 Want to show your support and get some extra perks? Become a member! https://www.youtube.com/channel/UCQ2g_IsL0inKrkc6omolPdA/join Show notes for this episode will be available after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: reachlevity.com LEVITY is co-hosted by Patrick Linden, philosopher and author, and Peter Ottsjö, journalist and author. ----- CHAPTERS 00:00 Introduction 03:27 Why Sweden lags behind in longevity science 08:04 Nordic registry & Swedish twin registry advantages; UK Biobank use 10:05 What is biological age? 16:33 The rise of epigenetic clocks 24:22 The importance of aging clocks 32:04 Beyond methylation: proteomic and metabolomic clocks 35:12 Organ clocks 39:37 Do aging clocks generalize? 54:37 The cost of aging clocks 01:03:18 Uncertain https://www.youtube-nocookie.com/embed/vsNhfGI4jYA 5783 2025-10-28T17:01:40.000Z 2026-10-22T19:32:34.499Z https://longevityharbor.com/en/watch/vuqYTGcQPHk Podcast description: 12 hallmarks of aging and age-related decline https://i.ytimg.com/vi/vuqYTGcQPHk/hqdefault.jpg The description says aging arises from a network of biological changes called the 12 hallmarks of aging, and that the episode discusses how they interact and which may be influenced by lifestyle and medical interventions. https://www.youtube-nocookie.com/embed/vuqYTGcQPHk 3926 2026-09-21T04:42:00.000Z 2026-10-22T22:03:04.604Z https://longevityharbor.com/de/watch/vuqYTGcQPHk Podcast-Beschreibung: 12 Hallmarks des Alterns und altersbezogener Abbau https://i.ytimg.com/vi/vuqYTGcQPHk/hqdefault.jpg Laut Beschreibung entsteht Altern durch ein Netzwerk biologischer Veränderungen, die 12 Hallmarks des Alterns, und die Folge behandelt, wie sie zusammenwirken und welche durch Lebensstil und medizinische Interventionen beeinflusst werden könnten. https://www.youtube-nocookie.com/embed/vuqYTGcQPHk 3926 2026-09-21T04:42:00.000Z 2026-10-22T22:03:04.604Z https://longevityharbor.com/en/watch/vvmMY2td_kk Age Later: Health Span, Life Span, and the New… by Nir Barzilai, M.D. · Audiobook preview https://i.ytimg.com/vi/vvmMY2td_kk/hqdefault.jpg PURCHASE ON GOOGLE PLAY BOOKS ►► https://g.co/booksYT/AQAAAEDsOC540M Age Later: Health Span, Life Span, and the New Science of Longevity Authored by Nir Barzilai, M.D. Narrated by Sean Pratt 0:00 Intro 0:03 Age Later: Health Span, Life Span, and the New Science of Longevity 0:36 Introduction 12:27 One: One Hundred Years Young 15:36 Outro #nirbarzilaimd #agelaterhealthspanlifespanandthenewscienceoflongevity — GOOGLE PLAY BOOKS Find your next great read with Google Play Books. Google Play Books is a global digital bookstore offering ebooks, audiobooks, comics, and manga. Discover book recommendations personalized just for you. Get the iOS app: https://goo.gle/books-ios Get the Android app: https://goo.gle/books-android — BOOK DESCRIPTION How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties? Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age–related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s. One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers—individuals who maintain active lives well into their nineties and even beyond—and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline. In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye–opening and inspirational audiobook will help you think of aging not as a certainty, but as a phenomenon—li https://www.youtube-nocookie.com/embed/vvmMY2td_kk 958 2024-01-31T08:11:05.000Z 2026-10-22T19:54:20.337Z https://longevityharbor.com/de/watch/vvmMY2td_kk Age Later: Health Span, Life Span, and the New… by Nir Barzilai, M.D. · Audiobook preview https://i.ytimg.com/vi/vvmMY2td_kk/hqdefault.jpg PURCHASE ON GOOGLE PLAY BOOKS ►► https://g.co/booksYT/AQAAAEDsOC540M Age Later: Health Span, Life Span, and the New Science of Longevity Authored by Nir Barzilai, M.D. Narrated by Sean Pratt 0:00 Intro 0:03 Age Later: Health Span, Life Span, and the New Science of Longevity 0:36 Introduction 12:27 One: One Hundred Years Young 15:36 Outro #nirbarzilaimd #agelaterhealthspanlifespanandthenewscienceoflongevity — GOOGLE PLAY BOOKS Find your next great read with Google Play Books. Google Play Books is a global digital bookstore offering ebooks, audiobooks, comics, and manga. Discover book recommendations personalized just for you. Get the iOS app: https://goo.gle/books-ios Get the Android app: https://goo.gle/books-android — BOOK DESCRIPTION How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties? Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age–related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s. One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers—individuals who maintain active lives well into their nineties and even beyond—and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline. In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye–opening and inspirational audiobook will help you think of aging not as a certainty, but as a phenomenon—li https://www.youtube-nocookie.com/embed/vvmMY2td_kk 958 2024-01-31T08:11:05.000Z 2026-10-22T19:54:20.337Z https://longevityharbor.com/en/watch/vyilDPH2KPA The Promise of Senolytics to Treat Aging with Dr. James L. Kirkland https://i.ytimg.com/vi/vyilDPH2KPA/hqdefault.jpg In this episode, renowned aging researcher Dr. James L. Kirkland discusses cutting-edge research on cellular senescence and senolytics in aging. He explains how senescent cells accumulate over time, accelerating aging and contributing to age-related diseases. Dr. Kirkland highlights the potential of senolytic drugs to selectively eliminate these cells, potentially delaying or preventing age-related conditions such as osteoarthritis, Alzheimer's disease, and even the impact of coronavirus infections. The episode explores challenges with senolytic therapies and how senolytic research could extend healthspan and potentially address the societal challenges of an aging population. Note: This lecture was recorded in February 2023. Learn more about Dr. James L. Kirkland’s work: https://www.mayo.edu/research/faculty/kirkland-james-l-m-d-ph-d/bio-00096544 Learn more about Dr. David Dodick: https://www.atria.org/doctors/dr-david-w-dodick/ Time stamps: 00:00:17: Intro 00:03:05: Dr. James Kirkland on why geroscience is focused on improving healthspan as opposed to lifespan 00:05:30: The factors that impact the rate of aging 00:09:00: Cellular senescence explained 00:18:38: Developing drugs for cellular senescence 00:24:01: The role of senescent cells in pregnancy 00:24:44: Challenges to developing senolytics 00:25:36: Experimentation with senescent cells in mice 00:30:45: The spread of senescence in obesity and its effects on the brain 00:32:43: How senescent cells interact with SARS-CoV-2 00:35:20: Efforts to translate senolytic drugs to humans 00:42:00: Gerogiagnostics: Developing biomarkers that can guide interventions for targeting aging 00:46:00: Alpha-Klotho protein as a geroprotective factor and its relation to senolytics 00:48:30: Risks and benefits of clinical trials for people with serious conditions 00:53:00: The impact of senescence on childhood cancer survivors and the promise for other conditions beyond old age 00:54:44: Trials related to space travel 00:57:02: Conclusions on persistent senescent cells https://www.youtube-nocookie.com/embed/vyilDPH2KPA 3890 2025-05-05T04:01:09.000Z 2026-10-22T18:43:13.528Z https://longevityharbor.com/de/watch/vyilDPH2KPA The Promise of Senolytics to Treat Aging with Dr. James L. Kirkland https://i.ytimg.com/vi/vyilDPH2KPA/hqdefault.jpg In this episode, renowned aging researcher Dr. James L. Kirkland discusses cutting-edge research on cellular senescence and senolytics in aging. He explains how senescent cells accumulate over time, accelerating aging and contributing to age-related diseases. Dr. Kirkland highlights the potential of senolytic drugs to selectively eliminate these cells, potentially delaying or preventing age-related conditions such as osteoarthritis, Alzheimer's disease, and even the impact of coronavirus infections. The episode explores challenges with senolytic therapies and how senolytic research could extend healthspan and potentially address the societal challenges of an aging population. Note: This lecture was recorded in February 2023. Learn more about Dr. James L. Kirkland’s work: https://www.mayo.edu/research/faculty/kirkland-james-l-m-d-ph-d/bio-00096544 Learn more about Dr. David Dodick: https://www.atria.org/doctors/dr-david-w-dodick/ Time stamps: 00:00:17: Intro 00:03:05: Dr. James Kirkland on why geroscience is focused on improving healthspan as opposed to lifespan 00:05:30: The factors that impact the rate of aging 00:09:00: Cellular senescence explained 00:18:38: Developing drugs for cellular senescence 00:24:01: The role of senescent cells in pregnancy 00:24:44: Challenges to developing senolytics 00:25:36: Experimentation with senescent cells in mice 00:30:45: The spread of senescence in obesity and its effects on the brain 00:32:43: How senescent cells interact with SARS-CoV-2 00:35:20: Efforts to translate senolytic drugs to humans 00:42:00: Gerogiagnostics: Developing biomarkers that can guide interventions for targeting aging 00:46:00: Alpha-Klotho protein as a geroprotective factor and its relation to senolytics 00:48:30: Risks and benefits of clinical trials for people with serious conditions 00:53:00: The impact of senescence on childhood cancer survivors and the promise for other conditions beyond old age 00:54:44: Trials related to space travel 00:57:02: Conclusions on persistent senescent cells https://www.youtube-nocookie.com/embed/vyilDPH2KPA 3890 2025-05-05T04:01:09.000Z 2026-10-22T18:43:13.528Z https://longevityharbor.com/en/watch/w-hcQeKMGSU Senolytic Compounds Reduce Epigenetic Age of Blood Samples in Vitro https://i.ytimg.com/vi/w-hcQeKMGSU/hqdefault.jpg Senolytics are a group of small molecules that specifically target senescent cells by interfering with their anti-apoptotic signaling pathways and inducing apoptosis. Studies have shown that senolytic treatments can selectively remove senescent cells, reduce proinflammatory cytokines and prolong t #senolytics Rationale behind our study Most of the in vitro studies performed to date have been based on modelling the senescence system by artificially inducing DNA damage through radiation or inflammatory cytokines to show that senolytics have the potential to eliminate these cells. There is a lack of studies to quantify and understand senolytic treatment in primary blood samples and especially in healthy aging humans. Therefore, we hypothesized that targeting these cells with senolytic drugs may have the potential to reduce epigenetic aging and other markers associated with senescence. Key Findings Epigenetic age reduction: A three-day senolytic treatment of human peripheral blood mononuclear cells (PBMCs) in vitro showed a reduction in epigenetic age as measured by DNA methylation changes in age-associated regions. Elimination of senescent cells: Senolytic treatment resulted in a decrease in senescent markers such as senescence-associated β-galactosidase with C12FDG and p16INK4a expression, as well as a shift within blood cell composition. Effective senolytic compounds: Four drugs showed an overall effect on both epigenetic age and cellular senescence: JQ1 is an effective inhibitor of the BET family that targets the DNA repair pathway of the non-homologous end joining. The other three drugs, RG7112, AMG232 and nutlin-3a, are MDM2 inhibitors that disrupt with the interaction between p53 and MDM2, leading to a stabilized p53 and promoting apoptosis in senescent cells. Dr. Noor Gajraj is a leading educator and physician in his field. He has practiced medicine for more than 25 years in the United Kingdom and the United States. He has been an Associate Professor of Anesthesiology and Pain Management at U.T. Southw https://www.youtube-nocookie.com/embed/w-hcQeKMGSU 838 2025-03-13T13:08:12.000Z 2026-10-22T18:43:13.540Z https://longevityharbor.com/de/watch/w-hcQeKMGSU Senolytic Compounds Reduce Epigenetic Age of Blood Samples in Vitro https://i.ytimg.com/vi/w-hcQeKMGSU/hqdefault.jpg Senolytics are a group of small molecules that specifically target senescent cells by interfering with their anti-apoptotic signaling pathways and inducing apoptosis. Studies have shown that senolytic treatments can selectively remove senescent cells, reduce proinflammatory cytokines and prolong t #senolytics Rationale behind our study Most of the in vitro studies performed to date have been based on modelling the senescence system by artificially inducing DNA damage through radiation or inflammatory cytokines to show that senolytics have the potential to eliminate these cells. There is a lack of studies to quantify and understand senolytic treatment in primary blood samples and especially in healthy aging humans. Therefore, we hypothesized that targeting these cells with senolytic drugs may have the potential to reduce epigenetic aging and other markers associated with senescence. Key Findings Epigenetic age reduction: A three-day senolytic treatment of human peripheral blood mononuclear cells (PBMCs) in vitro showed a reduction in epigenetic age as measured by DNA methylation changes in age-associated regions. Elimination of senescent cells: Senolytic treatment resulted in a decrease in senescent markers such as senescence-associated β-galactosidase with C12FDG and p16INK4a expression, as well as a shift within blood cell composition. Effective senolytic compounds: Four drugs showed an overall effect on both epigenetic age and cellular senescence: JQ1 is an effective inhibitor of the BET family that targets the DNA repair pathway of the non-homologous end joining. The other three drugs, RG7112, AMG232 and nutlin-3a, are MDM2 inhibitors that disrupt with the interaction between p53 and MDM2, leading to a stabilized p53 and promoting apoptosis in senescent cells. Dr. Noor Gajraj is a leading educator and physician in his field. He has practiced medicine for more than 25 years in the United Kingdom and the United States. He has been an Associate Professor of Anesthesiology and Pain Management at U.T. Southw https://www.youtube-nocookie.com/embed/w-hcQeKMGSU 838 2025-03-13T13:08:12.000Z 2026-10-22T18:43:13.540Z https://longevityharbor.com/en/watch/w-zkwbAFHG0 Video description: AI-based epigenetic skin clocks for measuring skin aging https://i.ytimg.com/vi/w-zkwbAFHG0/hqdefault.jpg According to the description, researchers use artificial intelligence to analyse DNA methylation patterns in skin cells and thereby estimate age more precisely than traditional methods; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/w-zkwbAFHG0 360 2026-04-24T03:03:36.000Z 2026-10-23T01:29:53.302Z https://longevityharbor.com/de/watch/w-zkwbAFHG0 Videobeschreibung: KI-basierte epigenetische Hautuhren zur Messung der Hautalterung https://i.ytimg.com/vi/w-zkwbAFHG0/hqdefault.jpg Laut Beschreibung nutzen Forschende künstliche Intelligenz, um DNA-Methylierungsmuster in Hautzellen zu analysieren und so das Alter genauer als mit traditionellen Methoden zu schätzen; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/w-zkwbAFHG0 360 2026-04-24T03:03:36.000Z 2026-10-23T01:29:53.302Z https://longevityharbor.com/en/watch/w11vY25csdw Zombie Cells Explained: Senescence & Aging | YB50 Ep. 20 https://i.ytimg.com/vi/w11vY25csdw/hqdefault.jpg I just turned 57 — and I’ve learned that staying young is less about what’s in the mirror and more about what’s going on inside. Today we’re talking about “zombie cells” — cells that have stopped working but haven’t died. They linger, build up, and cause inflammation that accelerates aging in your joints, skin, energy levels, and even your brain. The good news? Senolytic supplements — made from natural, plant-based nutrients — help your body sweep out these damaged cells, making room for fresh growth and renewed vitality. 🌿 What are zombie cells and why do they matter? 🧬 What senescence is doing to your body behind the scenes 🧹 How senolytics work like a cellular clean-up crew 💊 Why I take one capsule a day to support this process You can’t stop aging — but you can support your body’s ability to age well. #YouthBeyond50 #WellnessWednesday #Senolytics Disclaimer: Testimonials shared in this video reflect individual experiences. They do not guarantee specific results, and outcomes can vary from person to person. https://www.youtube-nocookie.com/embed/w11vY25csdw 131 2026-03-18T16:45:11.000Z 2026-10-22T19:43:46.484Z https://longevityharbor.com/de/watch/w11vY25csdw Zombie Cells Explained: Senescence & Aging | YB50 Ep. 20 https://i.ytimg.com/vi/w11vY25csdw/hqdefault.jpg I just turned 57 — and I’ve learned that staying young is less about what’s in the mirror and more about what’s going on inside. Today we’re talking about “zombie cells” — cells that have stopped working but haven’t died. They linger, build up, and cause inflammation that accelerates aging in your joints, skin, energy levels, and even your brain. The good news? Senolytic supplements — made from natural, plant-based nutrients — help your body sweep out these damaged cells, making room for fresh growth and renewed vitality. 🌿 What are zombie cells and why do they matter? 🧬 What senescence is doing to your body behind the scenes 🧹 How senolytics work like a cellular clean-up crew 💊 Why I take one capsule a day to support this process You can’t stop aging — but you can support your body’s ability to age well. #YouthBeyond50 #WellnessWednesday #Senolytics Disclaimer: Testimonials shared in this video reflect individual experiences. They do not guarantee specific results, and outcomes can vary from person to person. https://www.youtube-nocookie.com/embed/w11vY25csdw 131 2026-03-18T16:45:11.000Z 2026-10-22T19:43:46.484Z https://longevityharbor.com/en/watch/w1GIImsNmIA Making Sense of Senolytics https://i.ytimg.com/vi/w1GIImsNmIA/hqdefault.jpg Making Sense of Senolytics https://www.youtube-nocookie.com/embed/w1GIImsNmIA 239 2021-08-26T21:35:39.000Z 2026-10-23T02:56:02.504Z https://longevityharbor.com/de/watch/w1GIImsNmIA Making Sense of Senolytics https://i.ytimg.com/vi/w1GIImsNmIA/hqdefault.jpg Making Sense of Senolytics https://www.youtube-nocookie.com/embed/w1GIImsNmIA 239 2021-08-26T21:35:39.000Z 2026-10-23T02:56:02.504Z https://longevityharbor.com/en/watch/w8MTM3zKsSA Podcast description: strength training for women, muscles and menopause https://i.ytimg.com/vi/w8MTM3zKsSA/hqdefault.jpg The description says the podcast episode with Sonja Schlarb of Kieser Schweiz covers why strength training matters for women at every age, how much is needed, and its links to metabolism, bones, osteoporosis and menopause. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/w8MTM3zKsSA 3743 2026-08-23T07:00:03.000Z 2026-10-22T22:48:50.333Z https://longevityharbor.com/de/watch/w8MTM3zKsSA Podcast-Beschreibung: Krafttraining für Frauen, Muskeln und Wechseljahre https://i.ytimg.com/vi/w8MTM3zKsSA/hqdefault.jpg Laut Beschreibung behandelt die Podcast-Folge mit Sonja Schlarb von Kieser Schweiz, warum Krafttraining für Frauen in jedem Alter wichtig ist, wie viel nötig ist und was es mit Stoffwechsel, Knochen, Osteoporose und Wechseljahren zu tun hat. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/w8MTM3zKsSA 3743 2026-08-23T07:00:03.000Z 2026-10-22T22:48:50.333Z https://longevityharbor.com/en/watch/wEQok0oIZBs Lecture description: sleep, dreaming and circadian rhythms in psychiatry https://i.ytimg.com/vi/wEQok0oIZBs/hqdefault.jpg The description says this psychiatry lecture covers the biological basis of sleep, neurotransmitters in sleep and wakefulness, perceptual disengagement, sleep architecture across the lifespan, and the clinical significance of REM and NREM sleep. https://www.youtube-nocookie.com/embed/wEQok0oIZBs 752 2026-07-10T15:19:43.000Z 2026-10-22T23:35:38.608Z https://longevityharbor.com/de/watch/wEQok0oIZBs Vorlesungsbeschreibung: Schlaf, Träume und zirkadiane Rhythmen in der Psychiatrie https://i.ytimg.com/vi/wEQok0oIZBs/hqdefault.jpg Laut Beschreibung behandelt diese Psychiatrie-Vorlesung die biologischen Grundlagen des Schlafs, Neurotransmitter bei Schlaf und Wachheit, perzeptuelle Abkopplung, die Schlafarchitektur über die Lebensspanne und die klinische Bedeutung von REM- und NREM-Schlaf. https://www.youtube-nocookie.com/embed/wEQok0oIZBs 752 2026-07-10T15:19:43.000Z 2026-10-22T23:35:38.608Z https://longevityharbor.com/en/watch/wFYXd7Q0aUU Food for Thought: The Role of Nutrition in Healthy Aging (CC) https://i.ytimg.com/vi/wFYXd7Q0aUU/hqdefault.jpg The way we eat throughout our lives impacts the way we age. Science has proven that a well-balanced and varied diet full of nutritious foods like fruits and veggies, whole grains, legumes, nuts, and lean proteins; and limited in sugar, salt, saturated or solid fats, and alcoholic beverages; is critical to good health. This means we all have the power to maximize and improve our health, add vitality to our years, reduce the risk of disease, and increase our healthspans—the number of years we live in good health. And research shows that it’s never too late to make improvements. Without proper nutrition our bodies can’t stay healthy, fight off disease, or deal with illnesses that we already have. Poor nutrition weakens our immune systems and leaves us vulnerable to infections, and slower recovery and wound healing. It also causes unhealthy weight changes and muscle loss that can lead to frailty, falls, broken bones, disability, loss of independence, and disease complications. It can also lead to nutrition-related diseases and conditions. The latest Dietary Guidelines from the U.S. Department of Agriculture, address nutrition at various life stages and provide important recommendations on achieving a well-rounded diet. The guidelines emphasize that the foods and beverages we consume have a profound impact on our health—now and in the years to come—but MOST Americans don’t follow a healthy dietary pattern. They also highlight the fact that our nutrition decisions add up “bite by bite” and are important at every age. Also available in Spanish at https://www.youtube.com/watch?v=GGZmwN0kEqU. https://www.youtube-nocookie.com/embed/wFYXd7Q0aUU 391 2021-05-10T15:37:01.000Z 2026-10-23T01:53:57.173Z https://longevityharbor.com/de/watch/wFYXd7Q0aUU Food for Thought: The Role of Nutrition in Healthy Aging (CC) https://i.ytimg.com/vi/wFYXd7Q0aUU/hqdefault.jpg The way we eat throughout our lives impacts the way we age. Science has proven that a well-balanced and varied diet full of nutritious foods like fruits and veggies, whole grains, legumes, nuts, and lean proteins; and limited in sugar, salt, saturated or solid fats, and alcoholic beverages; is critical to good health. This means we all have the power to maximize and improve our health, add vitality to our years, reduce the risk of disease, and increase our healthspans—the number of years we live in good health. And research shows that it’s never too late to make improvements. Without proper nutrition our bodies can’t stay healthy, fight off disease, or deal with illnesses that we already have. Poor nutrition weakens our immune systems and leaves us vulnerable to infections, and slower recovery and wound healing. It also causes unhealthy weight changes and muscle loss that can lead to frailty, falls, broken bones, disability, loss of independence, and disease complications. It can also lead to nutrition-related diseases and conditions. The latest Dietary Guidelines from the U.S. Department of Agriculture, address nutrition at various life stages and provide important recommendations on achieving a well-rounded diet. The guidelines emphasize that the foods and beverages we consume have a profound impact on our health—now and in the years to come—but MOST Americans don’t follow a healthy dietary pattern. They also highlight the fact that our nutrition decisions add up “bite by bite” and are important at every age. Also available in Spanish at https://www.youtube.com/watch?v=GGZmwN0kEqU. https://www.youtube-nocookie.com/embed/wFYXd7Q0aUU 391 2021-05-10T15:37:01.000Z 2026-10-23T01:53:57.173Z https://longevityharbor.com/en/watch/wHbEYwQbIh8 mTOR in Aging Ep4 - Rapamycin and Rapalogs | Dr David Sabatini Interview Series https://i.ytimg.com/vi/wHbEYwQbIh8/hqdefault.jpg In this video Dr. Sabatini discusses rapamycin, how it acts on mTORC1 and mTORC2 and the rapalogs, drugs which are similar to rapamycin but may be more clinically effective. Dr. David Sabatini is an American scientist and Professor of Biology at the Massachusetts Institute of Technology as well as a member of the Whitehead Institute for Biomedical Research. He is known for his important contributions in the areas of cell signaling and cancer metabolism, most notably the discovery of mTOR, more than 20 years ago. Since then Dr. Sabatini has continued to work on better understanding this complex regulator of our metabolism Some key references. Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction https://www.biorxiv.org/content/10.1101/2020.10.22.351361v1.full.pdf Twenty-five years of mTOR: Uncovering the link from nutrients to growth https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692607/ mTOR introduction YouTube Series with Dr. Sabatini https://www.youtube.com/watch?v=EnIerDljc7g https://www.youtube.com/watch?v=defOfBEuw_M https://www.youtube.com/watch?v=tGA9RALG66s #rapamycin #rapalogs #mtor #davidsabatini #MIT #healthspan https://www.youtube-nocookie.com/embed/wHbEYwQbIh8 524 2020-12-14T23:04:11.000Z 2026-10-22T17:43:41.076Z https://longevityharbor.com/de/watch/wHbEYwQbIh8 mTOR in Aging Ep4 - Rapamycin and Rapalogs | Dr David Sabatini Interview Series https://i.ytimg.com/vi/wHbEYwQbIh8/hqdefault.jpg In this video Dr. Sabatini discusses rapamycin, how it acts on mTORC1 and mTORC2 and the rapalogs, drugs which are similar to rapamycin but may be more clinically effective. Dr. David Sabatini is an American scientist and Professor of Biology at the Massachusetts Institute of Technology as well as a member of the Whitehead Institute for Biomedical Research. He is known for his important contributions in the areas of cell signaling and cancer metabolism, most notably the discovery of mTOR, more than 20 years ago. Since then Dr. Sabatini has continued to work on better understanding this complex regulator of our metabolism Some key references. Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction https://www.biorxiv.org/content/10.1101/2020.10.22.351361v1.full.pdf Twenty-five years of mTOR: Uncovering the link from nutrients to growth https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692607/ mTOR introduction YouTube Series with Dr. Sabatini https://www.youtube.com/watch?v=EnIerDljc7g https://www.youtube.com/watch?v=defOfBEuw_M https://www.youtube.com/watch?v=tGA9RALG66s #rapamycin #rapalogs #mtor #davidsabatini #MIT #healthspan https://www.youtube-nocookie.com/embed/wHbEYwQbIh8 524 2020-12-14T23:04:11.000Z 2026-10-22T17:43:41.076Z https://longevityharbor.com/en/watch/wIAC0ecA1l8 Hallmarks of Aging Ep.12 Chronic iniflammation https://i.ytimg.com/vi/wIAC0ecA1l8/hqdefault.jpg Chronic inflammation เป็นสาเหตุหนึ่งของการเสื่อมชราในระดับเซลล์และมีความสัมพันธ์อย่างมากกับ hallmarks อื่นๆ การจัดการกับการอักเสบเรื้อรังในร่างกายจะเป็นตัวช่วยที่ทำให้ชะลอความเสื่อมในระดับเซลล์ได้ #Hallmarksofaging #chronicinflammation #inflammation #longevity #THELONGEVIST #สุขภาพดี #อายุยืน https://www.youtube-nocookie.com/embed/wIAC0ecA1l8 3027 2023-11-19T21:53:30.000Z 2026-10-22T19:54:19.398Z https://longevityharbor.com/de/watch/wIAC0ecA1l8 Hallmarks of Aging Ep.12 Chronic iniflammation https://i.ytimg.com/vi/wIAC0ecA1l8/hqdefault.jpg Chronic inflammation เป็นสาเหตุหนึ่งของการเสื่อมชราในระดับเซลล์และมีความสัมพันธ์อย่างมากกับ hallmarks อื่นๆ การจัดการกับการอักเสบเรื้อรังในร่างกายจะเป็นตัวช่วยที่ทำให้ชะลอความเสื่อมในระดับเซลล์ได้ #Hallmarksofaging #chronicinflammation #inflammation #longevity #THELONGEVIST #สุขภาพดี #อายุยืน https://www.youtube-nocookie.com/embed/wIAC0ecA1l8 3027 2023-11-19T21:53:30.000Z 2026-10-22T19:54:19.398Z https://longevityharbor.com/en/watch/wL2QOuMWMSg Video description: rapamycin as a possible future anti-aging drug https://i.ytimg.com/vi/wL2QOuMWMSg/hqdefault.jpg In the description, Dr A presents rapamycin as a drug being studied for anti-aging effects, says it works by reducing mTOR, and stresses that use requires a doctor's supervision because unsupervised use can have side effects. https://www.youtube-nocookie.com/embed/wL2QOuMWMSg 158 2026-07-01T20:00:01.000Z 2026-10-22T23:41:43.846Z https://longevityharbor.com/de/watch/wL2QOuMWMSg Videobeschreibung: Rapamycin als mögliches künftiges Anti-Aging-Mittel https://i.ytimg.com/vi/wL2QOuMWMSg/hqdefault.jpg In der Beschreibung stellt Dr A Rapamycin als ein Mittel dar, das auf Anti-Aging-Wirkungen untersucht wird, sagt, es wirke durch Verringerung von mTOR, und betont, dass die Anwendung ärztliche Aufsicht erfordert, weil eine Anwendung ohne Aufsicht Nebenwirkungen haben kann. https://www.youtube-nocookie.com/embed/wL2QOuMWMSg 158 2026-07-01T20:00:01.000Z 2026-10-22T23:41:43.846Z https://longevityharbor.com/en/watch/wQx-xJdPFtU UC Berkeley Aging & Longevity Conference Day 2 - Dr. Felipe Sierra (Geroscience) 3-May-'26 https://i.ytimg.com/vi/wQx-xJdPFtU/hqdefault.jpg A Focus on Health Dr. Felipe Sierra https://www.youtube-nocookie.com/embed/wQx-xJdPFtU 1720 2026-05-13T02:02:21.000Z 2026-10-22T17:43:40.174Z https://longevityharbor.com/de/watch/wQx-xJdPFtU UC Berkeley Aging & Longevity Conference Day 2 - Dr. Felipe Sierra (Geroscience) 3-May-'26 https://i.ytimg.com/vi/wQx-xJdPFtU/hqdefault.jpg A Focus on Health Dr. Felipe Sierra https://www.youtube-nocookie.com/embed/wQx-xJdPFtU 1720 2026-05-13T02:02:21.000Z 2026-10-22T17:43:40.174Z https://longevityharbor.com/en/watch/wWCn8u-JCbU Video description: intermittent fasting and claimed metabolic, brain and gut effects https://i.ytimg.com/vi/wWCn8u-JCbU/hqdefault.jpg The description attributes to scientific sources claims that fasting triggers a switch to ketone use, boosts growth hormone, supports brain plasticity, reduces oxidative stress, improves insulin sensitivity and may reshape gut microbiota; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/wWCn8u-JCbU 425 2026-02-17T15:01:47.000Z 2026-10-23T02:28:29.528Z https://longevityharbor.com/de/watch/wWCn8u-JCbU Videobeschreibung: Intervallfasten und behauptete Stoffwechsel-, Hirn- und Darmeffekte https://i.ytimg.com/vi/wWCn8u-JCbU/hqdefault.jpg Die Beschreibung schreibt wissenschaftlichen Quellen zu, dass Fasten einen Wechsel zur Ketonnutzung auslöst, Wachstumshormon steigert, Hirnplastizität fördert, oxidativen Stress senkt, die Insulinempfindlichkeit verbessert und die Darmflora umformen kann; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/wWCn8u-JCbU 425 2026-02-17T15:01:47.000Z 2026-10-23T02:28:29.528Z https://longevityharbor.com/en/watch/wYTkiCL8ImU Video description: fasting, metabolism and longevity claims https://i.ytimg.com/vi/wYTkiCL8ImU/hqdefault.jpg The description says the video covers how fasting affects metabolism and longevity, including fat burning, insulin sensitivity, autophagy and cellular repair, and how ancient fasting practices are said to align with modern research. It also invites viewers to contact a clinic. https://www.youtube-nocookie.com/embed/wYTkiCL8ImU 1082 2026-03-25T17:30:08.000Z 2026-10-23T01:52:09.332Z https://longevityharbor.com/de/watch/wYTkiCL8ImU Videobeschreibung: Fasten, Stoffwechsel und Langlebigkeitsaussagen https://i.ytimg.com/vi/wYTkiCL8ImU/hqdefault.jpg Laut Beschreibung behandelt das Video, wie Fasten den Stoffwechsel und die Langlebigkeit beeinflusst, darunter Fettverbrennung, Insulinempfindlichkeit, Autophagie und Zellreparatur, und wie alte Fastenpraktiken mit moderner Forschung übereinstimmen sollen. Zudem lädt sie zur Kontaktaufnahme mit einer Klinik ein. https://www.youtube-nocookie.com/embed/wYTkiCL8ImU 1082 2026-03-25T17:30:08.000Z 2026-10-23T01:52:09.332Z https://longevityharbor.com/en/watch/w_KUXSIJYoQ Podcast description: Verdin on metabolism, immunity and aging biology https://i.ytimg.com/vi/w_KUXSIJYoQ/hqdefault.jpg In this podcast description, Dr. Eric Verdin of the Buck Institute discusses what drives aging, covering metabolism, NAD+, ketone bodies, insulin signaling, inflammation, immune aging, longevity drugs, lifestyle and biomarkers. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/w_KUXSIJYoQ 3012 2026-05-27T16:30:28.000Z 2026-10-23T00:19:18.322Z https://longevityharbor.com/de/watch/w_KUXSIJYoQ Podcast-Beschreibung: Verdin über Stoffwechsel, Immunsystem und Alternsbiologie https://i.ytimg.com/vi/w_KUXSIJYoQ/hqdefault.jpg In dieser Podcast-Beschreibung spricht Dr. Eric Verdin vom Buck Institute darüber, was das Altern antreibt: Stoffwechsel, NAD+, Ketonkörper, Insulinsignale, Entzündung, Immunaltern, Longevity-Medikamente, Lebensstil und Biomarker. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/w_KUXSIJYoQ 3012 2026-05-27T16:30:28.000Z 2026-10-23T00:19:18.322Z https://longevityharbor.com/en/watch/w_dL4DtpdY8 Senior Muscle video proposes glute and thigh exercises for adults over 50 https://i.ytimg.com/vi/w_dL4DtpdY8/hqdefault.jpg The description presents one lower-body exercise with glute- and thigh-focused variations for adults over 50, aiming to support strength, balance and daily movement; it reports no study results. https://www.youtube-nocookie.com/embed/w_dL4DtpdY8 795 2026-05-29T12:05:26.000Z 2026-10-23T00:18:38.930Z https://longevityharbor.com/de/watch/w_dL4DtpdY8 Senior-Muscle-Video schlägt Übungen für Gesäß und Oberschenkel für Erwachsene über 50 vor https://i.ytimg.com/vi/w_dL4DtpdY8/hqdefault.jpg Die Beschreibung stellt eine Unterkörperübung mit Varianten für Gesäß und Oberschenkel für Erwachsene über 50 vor, um Kraft, Gleichgewicht und Alltagsbewegung zu unterstützen; Studienergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/w_dL4DtpdY8 795 2026-05-29T12:05:26.000Z 2026-10-23T00:18:38.930Z https://longevityharbor.com/en/watch/w_x5VH9DfOg Human Longevity Research: Stem Cells, Hormones & NMN | Peter Diamandis https://i.ytimg.com/vi/w_x5VH9DfOg/hqdefault.jpg In this insightful episode, we explore cutting-edge human longevity research, with a focus on stem cell therapies, hormone replacement, and NMN. In our conversation, we cover how these innovations are helping to restore balance, fight muscle loss, and extend healthspan. Discover the future of anti-aging medicine and learn what you can do today to optimize your health for the long term. 00:00 - 00:25: Evolutionary legacies and the decline of hormones and enzymes. 00:35 - 01:12: The importance of hormone and peptide therapy for achieving homeostasis. 01:27 - 03:29: Overview of stem cell therapies and their potential in regenerative medicine. 03:41 - 05:01: Global availability and the future of stem cell treatments. 05:17 - 05:48: Scientific measures and the importance of data collection in stem cell therapy. 05:59 - 06:33: Stem cell exhaustion as a hallmark of aging and its implications. 06:45 - 08:14: The role of NAD and NMN in mitochondrial health and ongoing research. 08:24 - 08:51: Future breakthroughs in anti-aging research and maintaining a positive mindset. #Longevity #AntiAging #StemCells #HormoneTherapy #NAD #NMN #HealthOptimization #Biohacking #Healthspan #regenerativemedicine #peterdiamandis 🔔 Subscribe to my channel for more episodes 👍 Like and share this video 💬 Comment below with your thoughts on longevity Discover my NEW BOOK and listen to Chapter 1 FREE here: https://drstephensideroff.com/lp/first-chapter/ Connect with me: ► Facebook: https://www.facebook.com/stephen.sideroff ► Instagram: https://www.instagram.com/drstephensideroff/ ► Linkedin: https://www.linkedin.com/in/drstephensideroff/ Through my online programs and social communities, we’ve helped countless people break free from frozen beliefs, thinking, and feelings to find more joy and success in their lives. Ready to master your stress and create the life you always wanted? I want to help you do the same with my 9 pillars of resilience. SUBSCRIBE TO MY NEWSLETTER Discover the latest discoveries and breakthroughs on transfor https://www.youtube-nocookie.com/embed/w_x5VH9DfOg 533 2024-08-29T22:01:47.000Z 2026-10-22T20:11:48.128Z https://longevityharbor.com/de/watch/w_x5VH9DfOg Human Longevity Research: Stem Cells, Hormones & NMN | Peter Diamandis https://i.ytimg.com/vi/w_x5VH9DfOg/hqdefault.jpg In this insightful episode, we explore cutting-edge human longevity research, with a focus on stem cell therapies, hormone replacement, and NMN. In our conversation, we cover how these innovations are helping to restore balance, fight muscle loss, and extend healthspan. Discover the future of anti-aging medicine and learn what you can do today to optimize your health for the long term. 00:00 - 00:25: Evolutionary legacies and the decline of hormones and enzymes. 00:35 - 01:12: The importance of hormone and peptide therapy for achieving homeostasis. 01:27 - 03:29: Overview of stem cell therapies and their potential in regenerative medicine. 03:41 - 05:01: Global availability and the future of stem cell treatments. 05:17 - 05:48: Scientific measures and the importance of data collection in stem cell therapy. 05:59 - 06:33: Stem cell exhaustion as a hallmark of aging and its implications. 06:45 - 08:14: The role of NAD and NMN in mitochondrial health and ongoing research. 08:24 - 08:51: Future breakthroughs in anti-aging research and maintaining a positive mindset. #Longevity #AntiAging #StemCells #HormoneTherapy #NAD #NMN #HealthOptimization #Biohacking #Healthspan #regenerativemedicine #peterdiamandis 🔔 Subscribe to my channel for more episodes 👍 Like and share this video 💬 Comment below with your thoughts on longevity Discover my NEW BOOK and listen to Chapter 1 FREE here: https://drstephensideroff.com/lp/first-chapter/ Connect with me: ► Facebook: https://www.facebook.com/stephen.sideroff ► Instagram: https://www.instagram.com/drstephensideroff/ ► Linkedin: https://www.linkedin.com/in/drstephensideroff/ Through my online programs and social communities, we’ve helped countless people break free from frozen beliefs, thinking, and feelings to find more joy and success in their lives. Ready to master your stress and create the life you always wanted? I want to help you do the same with my 9 pillars of resilience. SUBSCRIBE TO MY NEWSLETTER Discover the latest discoveries and breakthroughs on transfor https://www.youtube-nocookie.com/embed/w_x5VH9DfOg 533 2024-08-29T22:01:47.000Z 2026-10-22T20:11:48.128Z https://longevityharbor.com/en/watch/wdtCTC-FSKA Video description: immune decline with age called only half true https://i.ytimg.com/vi/wdtCTC-FSKA/hqdefault.jpg The description says immune decline with age is only half true: chronic inflammation rises as the immune system hyperactivates against the wrong targets. It links to a full episode; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/wdtCTC-FSKA 98 2026-08-07T16:32:21.000Z 2026-10-22T23:09:24.588Z https://longevityharbor.com/de/watch/wdtCTC-FSKA Videobeschreibung: Immunabbau im Alter nur halb wahr genannt https://i.ytimg.com/vi/wdtCTC-FSKA/hqdefault.jpg Die Beschreibung nennt den Immunabbau im Alter nur halb wahr: Chronische Entzündung steigt, während das Immunsystem gegen die falschen Ziele überaktiv wird. Sie verweist auf eine ganze Folge; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/wdtCTC-FSKA 98 2026-08-07T16:32:21.000Z 2026-10-22T23:09:24.588Z https://longevityharbor.com/en/watch/weUrA9Tk_yA Video description lists five exercises for strength with age https://i.ytimg.com/vi/weUrA9Tk_yA/hqdefault.jpg The description presents five basic movements—hanging and grip, deep squat, sit-to-stand and floor-to-stand, hip mobility, and isometric strength and balance—as ways to support strength, mobility and independence with age. https://www.youtube-nocookie.com/embed/weUrA9Tk_yA 547 2026-09-30T17:00:16.000Z 2026-10-22T21:36:01.877Z https://longevityharbor.com/de/watch/weUrA9Tk_yA Videobeschreibung nennt fünf Übungen für Kraft im Alter https://i.ytimg.com/vi/weUrA9Tk_yA/hqdefault.jpg Die Beschreibung stellt fünf Grundbewegungen vor – Hängen und Griffkraft, tiefe Kniebeuge, Aufstehen vom Stuhl und vom Boden, Hüftmobilität sowie isometrische Kraft und Balance – als Wege, Kraft, Mobilität und Selbstständigkeit im Alter zu unterstützen. https://www.youtube-nocookie.com/embed/weUrA9Tk_yA 547 2026-09-30T17:00:16.000Z 2026-10-22T21:36:01.877Z https://longevityharbor.com/en/watch/wiIdFAWqmcQ Webinar description: circadian rhythm, intermittent fasting and type-2 diabetes https://i.ytimg.com/vi/wiIdFAWqmcQ/hqdefault.jpg The description announces an AFAR webinar from June 29, 2022 in which Satchin Panda discussed his research on intermittent fasting and circadian cycles to promote healthy aging, framed by the question whether following the body's circadian rhythm can help manage and avoid type-2 diabetes. https://www.youtube-nocookie.com/embed/wiIdFAWqmcQ 3249 2026-01-20T20:36:10.000Z 2026-10-23T02:49:08.932Z https://longevityharbor.com/de/watch/wiIdFAWqmcQ Webinar-Beschreibung: circadianer Rhythmus, Intervallfasten und Typ-2-Diabetes https://i.ytimg.com/vi/wiIdFAWqmcQ/hqdefault.jpg Die Beschreibung kündigt ein AFAR-Webinar vom 29. Juni 2022 an, in dem Satchin Panda seine Forschung zu Intervallfasten und circadianen Zyklen zur Förderung gesunden Alterns vorstellte, gerahmt von der Frage, ob das Befolgen des circadianen Rhythmus des Körpers helfen kann, Typ-2-Diabetes zu managen und zu vermeiden. https://www.youtube-nocookie.com/embed/wiIdFAWqmcQ 3249 2026-01-20T20:36:10.000Z 2026-10-23T02:49:08.932Z https://longevityharbor.com/en/watch/wiR49TjiE3U “The Science Behind NMN: How It Boosts Energy and Slows Aging” https://i.ytimg.com/vi/wiR49TjiE3U/hqdefault.jpg This video shares information about NMN (Nicotinamide Mononucleotide) and the science behind how it works in our body — helping support energy, cell repair, and healthy aging. This content is for educational purposes only, intended to help viewers understand the role of NMN in boosting NAD+ levels and promoting better health. #NMN #AntiAging #HealthScience #CellEnergy #WellnessJourney https://www.youtube-nocookie.com/embed/wiR49TjiE3U 372 2025-10-23T16:29:57.000Z 2026-10-22T20:11:48.241Z https://longevityharbor.com/de/watch/wiR49TjiE3U “The Science Behind NMN: How It Boosts Energy and Slows Aging” https://i.ytimg.com/vi/wiR49TjiE3U/hqdefault.jpg This video shares information about NMN (Nicotinamide Mononucleotide) and the science behind how it works in our body — helping support energy, cell repair, and healthy aging. This content is for educational purposes only, intended to help viewers understand the role of NMN in boosting NAD+ levels and promoting better health. #NMN #AntiAging #HealthScience #CellEnergy #WellnessJourney https://www.youtube-nocookie.com/embed/wiR49TjiE3U 372 2025-10-23T16:29:57.000Z 2026-10-22T20:11:48.241Z https://longevityharbor.com/en/watch/wkoLdwssHRs Epigenetic clocks described for measuring biological aging across mammals https://i.ytimg.com/vi/wkoLdwssHRs/hqdefault.jpg The description outlines microarray-based DNA methylation measurement, first- and second-generation epigenetic clocks, a clock spanning many mammalian species, and possible applications; it reports no new study results. https://www.youtube-nocookie.com/embed/wkoLdwssHRs 673 2026-09-07T10:34:37.000Z 2026-10-22T22:28:02.629Z https://longevityharbor.com/de/watch/wkoLdwssHRs Beschriebene epigenetische Uhren zur Messung biologischen Alterns bei Säugetieren https://i.ytimg.com/vi/wkoLdwssHRs/hqdefault.jpg Die Beschreibung skizziert microarraybasierte DNA-Methylierungsmessung, epigenetische Uhren der ersten und zweiten Generation, eine Uhr für viele Säugetierarten und mögliche Anwendungen; neue Studienergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/wkoLdwssHRs 673 2026-09-07T10:34:37.000Z 2026-10-22T22:28:02.629Z https://longevityharbor.com/en/watch/wlGV083XFe4 Video description on NAD⁺ as a cellular coenzyme and its role in longevity discussions https://i.ytimg.com/vi/wlGV083XFe4/hqdefault.jpg According to the description, NAD⁺ is a central coenzyme in cell metabolism that supports energy processes, including in mitochondria, and is linked to repair and stress-response systems. The description says NAD⁺ levels can decline with age in many models and that this changes cell capacity. https://www.youtube-nocookie.com/embed/wlGV083XFe4 139 2025-12-29T18:23:52.000Z 2026-10-23T03:04:55.851Z https://longevityharbor.com/de/watch/wlGV083XFe4 Videobeschreibung zu NAD⁺ als zelluläres Coenzym und seiner Rolle in Longevity-Diskussionen https://i.ytimg.com/vi/wlGV083XFe4/hqdefault.jpg Laut Beschreibung ist NAD⁺ ein zentrales Coenzym im Zellstoffwechsel, das Energieprozesse unterstützt, unter anderem in den Mitochondrien, und mit Reparatur- und Stressantwort-Systemen zusammenhängt. Die Beschreibung sagt, NAD⁺-Spiegel können im Alter in vielen Modellen abnehmen und das verändere die Zell-Kapazität. https://www.youtube-nocookie.com/embed/wlGV083XFe4 139 2025-12-29T18:23:52.000Z 2026-10-23T03:04:55.851Z https://longevityharbor.com/en/watch/wnlrRSqGayA Mouse myografts that contract under the skin: described benefits, not a human anti-aging implant https://i.ytimg.com/vi/wnlrRSqGayA/hqdefault.jpg The description reports a Nature Aging mouse study in which small vascularized muscle grafts called myografts contracted under the skin and were associated with several whole-body changes. The creator stresses this is not an anti-aging implant for humans. https://www.youtube-nocookie.com/embed/wnlrRSqGayA 146 2026-08-27T08:46:52.000Z 2026-10-22T22:41:50.515Z https://longevityharbor.com/de/watch/wnlrRSqGayA Maus-Myografts, die unter der Haut kontrahieren: beschriebene Effekte, kein menschliches Anti-Aging- https://i.ytimg.com/vi/wnlrRSqGayA/hqdefault.jpg Die Beschreibung berichtet über eine Mausstudie in Nature Aging: Kleine vaskularisierte Muskeltransplantate, sogenannte Myografts, kontrahierten unter der Haut und waren mit mehreren systemischen Veränderungen assoziiert. Der Ersteller betont, dies sei kein Anti-Aging-Implantat für Menschen. https://www.youtube-nocookie.com/embed/wnlrRSqGayA 146 2026-08-27T08:46:52.000Z 2026-10-22T22:41:50.515Z https://longevityharbor.com/en/watch/wsLnPRUUGhQ Living for Longevity: The Nutrition Connection - Research on Aging https://i.ytimg.com/vi/wsLnPRUUGhQ/hqdefault.jpg Learn the right balance of foods to maximize your health and energy level through an anti-inflammatory eating plan. Vicky Newman, MS, RD, will provide practical tips for controlling your weight, maintaining bone strength, and reducing the risk of common chronic diseases associated with aging. Learn about foods that support the body’s immune and detoxification systems, how to maintain a healthy (and happy) gut, and balance your fats to support your health and well-being. [4/2013] [Show ID: 24547] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/wsLnPRUUGhQ 5371 2013-04-04T19:03:55.000Z 2026-10-23T01:53:57.244Z https://longevityharbor.com/de/watch/wsLnPRUUGhQ Living for Longevity: The Nutrition Connection - Research on Aging https://i.ytimg.com/vi/wsLnPRUUGhQ/hqdefault.jpg Learn the right balance of foods to maximize your health and energy level through an anti-inflammatory eating plan. Vicky Newman, MS, RD, will provide practical tips for controlling your weight, maintaining bone strength, and reducing the risk of common chronic diseases associated with aging. Learn about foods that support the body’s immune and detoxification systems, how to maintain a healthy (and happy) gut, and balance your fats to support your health and well-being. [4/2013] [Show ID: 24547] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/wsLnPRUUGhQ 5371 2013-04-04T19:03:55.000Z 2026-10-23T01:53:57.244Z https://longevityharbor.com/en/watch/x0gZHzSTdhg Epigenetic clocks and predictors of lifespan https://i.ytimg.com/vi/x0gZHzSTdhg/hqdefault.jpg Lecture by Steve Horvath on several epigenetic clocks. July 2019 https://www.youtube-nocookie.com/embed/x0gZHzSTdhg 5207 2019-08-10T17:55:18.000Z 2026-10-22T17:43:35.225Z https://longevityharbor.com/de/watch/x0gZHzSTdhg Epigenetic clocks and predictors of lifespan https://i.ytimg.com/vi/x0gZHzSTdhg/hqdefault.jpg Lecture by Steve Horvath on several epigenetic clocks. July 2019 https://www.youtube-nocookie.com/embed/x0gZHzSTdhg 5207 2019-08-10T17:55:18.000Z 2026-10-22T17:43:35.225Z https://longevityharbor.com/en/watch/x1lWwZuNCs4 EP20: Optimal Sleep Science: Master Your Circadian Clock for Health & Longevity #sleep https://i.ytimg.com/vi/x1lWwZuNCs4/hqdefault.jpg Unlock the science of optimal sleep! Learn how light, diet, and consistent schedules reset your biological clock. Plus, discover surprising risks of daytime napping and how to beat insomnia. Sleep smarter, live healthier! References: 1. Cortical activity upon awakening from sleep reveals consistent spatio-temporal gradients across sleep stages in human EEG. (2025). Current Biology, 35( ), 3812–3824. (https://doi.org/10.1016/j.cub.2025.06.064) 2. Naps and cardiovascular disease risk in different age and sex groups: evidence from a large community cohort. (2024). Journal of Clinical Sleep Medicine, 20(8), 1339–1348. 3. Association of outdoor artificial light at night with mental disorders and sleep patterns among US adolescents. (2020). JAMA Psychiatry, 77(12), 1266–1275. (https://doi.org/10.1001/jamapsychiatry.2020.1935) 4. Early morning university classes are associated with impaired sleep and academic performance. (2023). Nature Human Behaviour, X( ), X–X. (https://doi.org/10.1038/s41562-023-01531-x) 5. Preventing postpartum insomnia: findings from a three-arm randomized-controlled trial of cognitive behavioral therapy for insomnia, a responsive bassinet, and sleep hygiene. (2024). Sleep, X( ), X–X. (https://doi.org/10.1093/sleep/zsae106) 6. Altered sleep architecture following consecutive nights of presleep alcohol. (2024). Sleep, 47(4), X–X. (https://doi.org/10.1093/sleep/zsae003) 7. induced by mechanosensory stimulation provides cognitive and health benefits in Drosophila. (2024). Sleep, X( ), X–X. (https://doi.org/10.1093/sleep/zsae226) https://www.youtube-nocookie.com/embed/x1lWwZuNCs4 840 2025-10-21T01:01:05.000Z 2026-10-22T19:21:25.198Z https://longevityharbor.com/de/watch/x1lWwZuNCs4 EP20: Optimal Sleep Science: Master Your Circadian Clock for Health & Longevity #sleep https://i.ytimg.com/vi/x1lWwZuNCs4/hqdefault.jpg Unlock the science of optimal sleep! Learn how light, diet, and consistent schedules reset your biological clock. Plus, discover surprising risks of daytime napping and how to beat insomnia. Sleep smarter, live healthier! References: 1. Cortical activity upon awakening from sleep reveals consistent spatio-temporal gradients across sleep stages in human EEG. (2025). Current Biology, 35( ), 3812–3824. (https://doi.org/10.1016/j.cub.2025.06.064) 2. Naps and cardiovascular disease risk in different age and sex groups: evidence from a large community cohort. (2024). Journal of Clinical Sleep Medicine, 20(8), 1339–1348. 3. Association of outdoor artificial light at night with mental disorders and sleep patterns among US adolescents. (2020). JAMA Psychiatry, 77(12), 1266–1275. (https://doi.org/10.1001/jamapsychiatry.2020.1935) 4. Early morning university classes are associated with impaired sleep and academic performance. (2023). Nature Human Behaviour, X( ), X–X. (https://doi.org/10.1038/s41562-023-01531-x) 5. Preventing postpartum insomnia: findings from a three-arm randomized-controlled trial of cognitive behavioral therapy for insomnia, a responsive bassinet, and sleep hygiene. (2024). Sleep, X( ), X–X. (https://doi.org/10.1093/sleep/zsae106) 6. Altered sleep architecture following consecutive nights of presleep alcohol. (2024). Sleep, 47(4), X–X. (https://doi.org/10.1093/sleep/zsae003) 7. induced by mechanosensory stimulation provides cognitive and health benefits in Drosophila. (2024). Sleep, X( ), X–X. (https://doi.org/10.1093/sleep/zsae226) https://www.youtube-nocookie.com/embed/x1lWwZuNCs4 840 2025-10-21T01:01:05.000Z 2026-10-22T19:21:25.198Z https://longevityharbor.com/en/watch/x2OdTx-JC3I Six daily habits for healthy ageing after 55: what the video description covers https://i.ytimg.com/vi/x2OdTx-JC3I/hqdefault.jpg The video description lists six everyday habits for adults over 55 to 70: sleep without pressure, knowing your health values, protein and a Mediterranean diet, good hearing, social contact, and strength and balance. It names studies but reports no results. https://www.youtube-nocookie.com/embed/x2OdTx-JC3I 1645 2026-10-19T13:00:34.000Z 2026-10-22T19:50:28.426Z https://longevityharbor.com/de/watch/x2OdTx-JC3I Sechs Alltagsgewohnheiten für gesundes Älterwerden ab 55: Was die Videobeschreibung abdeckt https://i.ytimg.com/vi/x2OdTx-JC3I/hqdefault.jpg Die Videobeschreibung nennt sechs Alltagsgewohnheiten für Erwachsene über 55 bis 70: Schlaf ohne Druck, die eigenen Gesundheitswerte kennen, Eiweiß und mediterrane Ernährung, gutes Hören, soziale Kontakte sowie Kraft und Gleichgewicht. Sie nennt Studien, berichtet aber keine Ergebnisse. https://www.youtube-nocookie.com/embed/x2OdTx-JC3I 1645 2026-10-19T13:00:34.000Z 2026-10-22T19:50:28.426Z https://longevityharbor.com/en/watch/x553ShjmgYs If Exercise Were a Drug, Every Doctor Would Prescribe It (They Don't) | Dr. Mark Hyman https://i.ytimg.com/vi/x553ShjmgYs/hqdefault.jpg Imagine a new drug that offers a multitude of health benefits. This hypothetical drug dramatically improves blood pressure, blood sugar control, and aids in weight loss. It also supports heart health, boosts brain health, and contributes to muscle building, leading to increased strength. These health tips highlight the potential for a single intervention to impact numerous bodily functions, enhancing overall cognitive function and well-being. In this video, Dr. Mark Hyman breaks down the incredible science behind movement, nutrition, and the "Hallmarks of Aging." You'll learn exactly how physical activity regulates your longevity switches (like AMPK and sirtuins), protects your telomeres, and boosts cognitive function. Dr. Hyman also dives deep into the core principles of the Pegan Diet, explaining how food acts as biological information to reduce inflammation, heal your gut, and help you live a longer, more vibrant life. Whether you're looking to start a simple 10-minute daily movement routine or want a masterclass on cellular health and clearing out "zombie cells," this guide gives you the actionable, science-backed steps you need to take control of your biology today. #HealthAndWellness #FunctionalMedicine #Longevity #benefitsofexercise (0:00) Introduction and exercise as powerful, free medicine (2:17) Exercise’s impact on biological systems and aging (3:15) Types, amounts, and cognitive benefits of exercise (7:36) Real-life benefits and incorporating movement daily (12:53) Essential elements of eating well (14:50) Personalization and principles of the PEEKIN diet (24:23) Hallmarks of aging (27:11) Disrupted nutrient sensing and longevity switches (33:12) AMPK, sirtuins, and DNA damage (37:11) Telomere shortening and damaged proteins (41:21) Epigenetic damage and senescent (zombie) cells (45:26) Mitochondrial health and energy depletion (47:16) Importance of gut health (49:21) Stem cell exhaustion (50:46) Inflammaging and chronic inflammation (52:40) Reducing inflammation thr https://www.youtube-nocookie.com/embed/x553ShjmgYs 3183 2024-05-20T13:06:19.000Z 2026-10-22T19:54:19.264Z https://longevityharbor.com/de/watch/x553ShjmgYs If Exercise Were a Drug, Every Doctor Would Prescribe It (They Don't) | Dr. Mark Hyman https://i.ytimg.com/vi/x553ShjmgYs/hqdefault.jpg Imagine a new drug that offers a multitude of health benefits. This hypothetical drug dramatically improves blood pressure, blood sugar control, and aids in weight loss. It also supports heart health, boosts brain health, and contributes to muscle building, leading to increased strength. These health tips highlight the potential for a single intervention to impact numerous bodily functions, enhancing overall cognitive function and well-being. In this video, Dr. Mark Hyman breaks down the incredible science behind movement, nutrition, and the "Hallmarks of Aging." You'll learn exactly how physical activity regulates your longevity switches (like AMPK and sirtuins), protects your telomeres, and boosts cognitive function. Dr. Hyman also dives deep into the core principles of the Pegan Diet, explaining how food acts as biological information to reduce inflammation, heal your gut, and help you live a longer, more vibrant life. Whether you're looking to start a simple 10-minute daily movement routine or want a masterclass on cellular health and clearing out "zombie cells," this guide gives you the actionable, science-backed steps you need to take control of your biology today. #HealthAndWellness #FunctionalMedicine #Longevity #benefitsofexercise (0:00) Introduction and exercise as powerful, free medicine (2:17) Exercise’s impact on biological systems and aging (3:15) Types, amounts, and cognitive benefits of exercise (7:36) Real-life benefits and incorporating movement daily (12:53) Essential elements of eating well (14:50) Personalization and principles of the PEEKIN diet (24:23) Hallmarks of aging (27:11) Disrupted nutrient sensing and longevity switches (33:12) AMPK, sirtuins, and DNA damage (37:11) Telomere shortening and damaged proteins (41:21) Epigenetic damage and senescent (zombie) cells (45:26) Mitochondrial health and energy depletion (47:16) Importance of gut health (49:21) Stem cell exhaustion (50:46) Inflammaging and chronic inflammation (52:40) Reducing inflammation thr https://www.youtube-nocookie.com/embed/x553ShjmgYs 3183 2024-05-20T13:06:19.000Z 2026-10-22T19:54:19.264Z https://longevityharbor.com/en/watch/x8bhKEFLzqA Cell Cycle Status Influences Senescent Cell Responses to Senolytic Treatment | Aging-US https://i.ytimg.com/vi/x8bhKEFLzqA/hqdefault.jpg Aging-US #published this #research paper on August 7, 2025, in Volume 17, Issue 8, entitled “Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction" by #researchers from the Buck Institute for Research on Aging, Novato, CA; USC Leonard Davis School of Gerontology, Los Angeles, CA; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD; California Pacific Medical Center Research Institute, San Francisco, CA; Johns Hopkins Physical Sciences–Oncology Center and Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD. @HopkinsEngineer @buckinstituteforresearchon4229 #aging #cellularsenescence #senolytics #cellcycle #paperspotlight #openaccess #openscience #peerreviewed #journal #publication #publishing #meded DOI - https://doi.org/10.18632/aging.206299 Corresponding authors - Denis Wirtz — wirtz@jhu.edu, Pei-Hsun Wu — pwu@jhu.edu, and Birgit Schilling — bschilling@buckinstitute.org Abstract Cellular senescence has been strongly linked to aging and age-related diseases. It is well established that the phenotype of senescent cells is highly heterogeneous and influenced by their cell type and senescence-inducing stimulus. Recent single-cell RNA-sequencing studies identified heterogeneity within senescent cell populations. However, proof of functional differences between such subpopulations is lacking. To identify functionally distinct senescent cell subpopulations, we employed high-content image analysis to measure senescence marker expression in primary human endothelial cells and fibroblasts. We found that G2-arrested senescent cells feature higher senescence marker expression than G1-arrested senescent cells. To investigate functional differences, we compared IL-6 secretion and response to ABT263 senolytic treatment in G1 and G2 senescent cells. We determined that G2-arrested senescent cells secrete more IL-6 and are more sensitive to ABT263 than G1-arrested cells. We hypothesize that ce https://www.youtube-nocookie.com/embed/x8bhKEFLzqA 128 2025-09-22T18:09:16.000Z 2026-10-22T19:21:23.097Z https://longevityharbor.com/de/watch/x8bhKEFLzqA Cell Cycle Status Influences Senescent Cell Responses to Senolytic Treatment | Aging-US https://i.ytimg.com/vi/x8bhKEFLzqA/hqdefault.jpg Aging-US #published this #research paper on August 7, 2025, in Volume 17, Issue 8, entitled “Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction" by #researchers from the Buck Institute for Research on Aging, Novato, CA; USC Leonard Davis School of Gerontology, Los Angeles, CA; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD; California Pacific Medical Center Research Institute, San Francisco, CA; Johns Hopkins Physical Sciences–Oncology Center and Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD. @HopkinsEngineer @buckinstituteforresearchon4229 #aging #cellularsenescence #senolytics #cellcycle #paperspotlight #openaccess #openscience #peerreviewed #journal #publication #publishing #meded DOI - https://doi.org/10.18632/aging.206299 Corresponding authors - Denis Wirtz — wirtz@jhu.edu, Pei-Hsun Wu — pwu@jhu.edu, and Birgit Schilling — bschilling@buckinstitute.org Abstract Cellular senescence has been strongly linked to aging and age-related diseases. It is well established that the phenotype of senescent cells is highly heterogeneous and influenced by their cell type and senescence-inducing stimulus. Recent single-cell RNA-sequencing studies identified heterogeneity within senescent cell populations. However, proof of functional differences between such subpopulations is lacking. To identify functionally distinct senescent cell subpopulations, we employed high-content image analysis to measure senescence marker expression in primary human endothelial cells and fibroblasts. We found that G2-arrested senescent cells feature higher senescence marker expression than G1-arrested senescent cells. To investigate functional differences, we compared IL-6 secretion and response to ABT263 senolytic treatment in G1 and G2 senescent cells. We determined that G2-arrested senescent cells secrete more IL-6 and are more sensitive to ABT263 than G1-arrested cells. We hypothesize that ce https://www.youtube-nocookie.com/embed/x8bhKEFLzqA 128 2025-09-22T18:09:16.000Z 2026-10-22T19:21:23.097Z https://longevityharbor.com/en/watch/x8dyOg6F-qI Doctor's video: green leafy vegetables before sleep for eye health in older age https://i.ytimg.com/vi/x8dyOg6F-qI/hqdefault.jpg In the description, Dr. Markus Stein presents a three-step evening routine with cooked green leafy vegetables and a fat source, plus a five-minute eye ritual, as suggestions for eye health in older age. https://www.youtube-nocookie.com/embed/x8dyOg6F-qI 902 2026-09-04T10:14:28.000Z 2026-10-22T22:30:07.123Z https://longevityharbor.com/de/watch/x8dyOg6F-qI Arztvideo: grünes Blattgemüse vor dem Schlafen für gesunde Augen im Alter https://i.ytimg.com/vi/x8dyOg6F-qI/hqdefault.jpg In der Beschreibung stellt Dr. Markus Stein ein dreischrittiges Abendprotokoll mit gegartem grünem Blattgemüse und einer Fettquelle sowie ein Fünf-Minuten-Augenritual als Anregungen für die Augengesundheit im Alter vor. https://www.youtube-nocookie.com/embed/x8dyOg6F-qI 902 2026-09-04T10:14:28.000Z 2026-10-22T22:30:07.123Z https://longevityharbor.com/en/watch/xBCPRhYxrgg Senolytics explained: what the video description says about senescent cells https://i.ytimg.com/vi/xBCPRhYxrgg/hqdefault.jpg According to the description, senescent cells stop dividing but stay active and can release inflammatory signals; researchers are studying senolytics that may target them, mainly in early laboratory work. https://www.youtube-nocookie.com/embed/xBCPRhYxrgg 317 2026-03-11T09:26:27.000Z 2026-10-23T02:10:25.467Z https://longevityharbor.com/de/watch/xBCPRhYxrgg Senolytika erklärt: Was die Videobeschreibung über seneszente Zellen sagt https://i.ytimg.com/vi/xBCPRhYxrgg/hqdefault.jpg Laut Beschreibung teilen sich seneszente Zellen nicht mehr, bleiben aber aktiv und können entzündliche Signale abgeben; Forschende untersuchen Senolytika, die auf sie abzielen könnten, vor allem in frühen Laborarbeiten. https://www.youtube-nocookie.com/embed/xBCPRhYxrgg 317 2026-03-11T09:26:27.000Z 2026-10-23T02:10:25.467Z https://longevityharbor.com/en/watch/xBWdGO3RAUs Video description: does weakness drive faster aging via biological pathways? https://i.ytimg.com/vi/xBWdGO3RAUs/hqdefault.jpg The description says the creator argues weakness both predicts and mechanistically drives faster aging, walking through metabolic, inflammatory, behavioral, mitochondrial, hormonal, vascular, nutritional, sleep and psychological pathways, and presents resistance training as interrupting these pathways. https://www.youtube-nocookie.com/embed/xBWdGO3RAUs 1417 2026-09-04T22:00:00.000Z 2026-10-22T22:29:49.212Z https://longevityharbor.com/de/watch/xBWdGO3RAUs Videobeschreibung: Treibt Schwäche über biologische Wege schnelleres Altern voran? https://i.ytimg.com/vi/xBWdGO3RAUs/hqdefault.jpg Laut Beschreibung vertritt der Ersteller die These, dass Schwäche schnelleres Altern sowohl vorhersagt als auch mechanistisch antreibt; er geht metabolische, entzündliche, verhaltensbezogene, mitochondriale, hormonelle, vaskuläre, ernährungsbezogene, Schlaf- und psychologische Wege durch und stellt Krafttraining als Unterbrechung dieser Wege dar. https://www.youtube-nocookie.com/embed/xBWdGO3RAUs 1417 2026-09-04T22:00:00.000Z 2026-10-22T22:29:49.212Z https://longevityharbor.com/en/watch/xDovsfIdobg Semaglutide in aged female mice: lifespan and ageing markers https://i.ytimg.com/vi/xDovsfIdobg/hqdefault.jpg A description of a study in aged female mice reports that late-life semaglutide improved cognition, physical function and glucose control and raised median lifespan from 742 to 834 days. This is animal evidence, not a human lifespan benefit. https://www.youtube-nocookie.com/embed/xDovsfIdobg 128 2026-09-03T09:04:02.000Z 2026-10-22T22:30:42.989Z https://longevityharbor.com/de/watch/xDovsfIdobg Semaglutid bei gealterten weiblichen Mäusen: Lebensspanne und Alternsmarker https://i.ytimg.com/vi/xDovsfIdobg/hqdefault.jpg Eine Beschreibung einer Studie an gealterten weiblichen Mäusen berichtet, dass Semaglutid im späten Leben Kognition, körperliche Funktion und Glukosekontrolle verbesserte und die mediane Lebensspanne von 742 auf 834 Tage erhöhte. Das sind Tierdaten, kein menschlicher Lebensspannen-Nutzen. https://www.youtube-nocookie.com/embed/xDovsfIdobg 128 2026-09-03T09:04:02.000Z 2026-10-22T22:30:42.989Z https://longevityharbor.com/en/watch/xGhCy14YShs My Review of Peter Attia’s AMA: What I Agree & Disagree With https://i.ytimg.com/vi/xGhCy14YShs/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan In this episode, Matt shares his thoughts on Peter Attia's AMA , exploring areas of agreement and differing perspectives on health and longevity. Topics include the significance of grip strength, biomarkers for health assessment, exercise strategies while traveling, and advancements in longevity research like Klotho and GLP-1 agonists. Matt also discusses the role of AI in healthcare and addresses concerns about direct-to-consumer biological age tests. The episode concludes with a discussion of foundational exercises and the interconnected nature of aging and health. Timestamps: 0:00 Introduction 1:24 Why grip strength matters for longevity 5:50 Exercise strategies while traveling 9:34 Most important biomarkers for health 12:58 Advancements in longevity research: GLP-1 agonists and Klotho 20:05 The role of AI in healthcare and longevity 25:15 Debunking myths about biological age tests 30:45 Top 10 foundational exercises for fitness 36:13 Concluding thoughts and reflections on Peter Attia’s AMA Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified https://www.youtube-nocookie.com/embed/xGhCy14YShs 2769 2024-12-26T15:01:05.000Z 2026-10-22T19:32:34.276Z https://longevityharbor.com/de/watch/xGhCy14YShs My Review of Peter Attia’s AMA: What I Agree & Disagree With https://i.ytimg.com/vi/xGhCy14YShs/hqdefault.jpg Subscribe to our channel: https://www.youtube.com/@optispan In this episode, Matt shares his thoughts on Peter Attia's AMA , exploring areas of agreement and differing perspectives on health and longevity. Topics include the significance of grip strength, biomarkers for health assessment, exercise strategies while traveling, and advancements in longevity research like Klotho and GLP-1 agonists. Matt also discusses the role of AI in healthcare and addresses concerns about direct-to-consumer biological age tests. The episode concludes with a discussion of foundational exercises and the interconnected nature of aging and health. Timestamps: 0:00 Introduction 1:24 Why grip strength matters for longevity 5:50 Exercise strategies while traveling 9:34 Most important biomarkers for health 12:58 Advancements in longevity research: GLP-1 agonists and Klotho 20:05 The role of AI in healthcare and longevity 25:15 Debunking myths about biological age tests 30:45 Top 10 foundational exercises for fitness 36:13 Concluding thoughts and reflections on Peter Attia’s AMA Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified https://www.youtube-nocookie.com/embed/xGhCy14YShs 2769 2024-12-26T15:01:05.000Z 2026-10-22T19:32:34.276Z https://longevityharbor.com/en/watch/xHlNXzfCv0o The Biology of Aging https://i.ytimg.com/vi/xHlNXzfCv0o/hqdefault.jpg It is the greatest inevitability of life - aging. Have you ever wondered what happens within your body, that leads to its gradual decline in function and ultimately #aging? The longer we live, the more likely we are to develop age-related diseases; including cancer. In recent years, #science has taken big steps in understanding the biology of aging. Scientists have discovered nine biological hallmarks that contribute to the aging process. Here's how it works. More videos coming soon. Please rate☝️, comment👇, and subscribe☝️ if you like them, so that I can make more! Please send through requests for topics to cover as well. What do you want to learn about? #scienceinmotion   Check out other socials: TikTok - https://www.tiktok.com/@scienceinmotion Instagram - https://www.instagram.com/scienceinmotiongram/ Twitter - https://twitter.com/ScienceMotioner Facebook - https://www.facebook.com/Science-in-Motion-114470440455167 Website - https://scienceinmotion.wixsite.com/scienceinmotion Music thanks to:   Music by Adam Vitovský DOWNLOAD LINK: https://www.adamvitovsky.com/one-story Creative Commons — Attribution 3.0 Unported — CC BY 3.0   Images thanks to:   Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License.   Some images designed by Freepik/vectorpouch/pch.vector/vectorpocket . Available from: www.freepik.com Some images adapted from BioRender. Created with BioRender.com. Available from: https://biorender.com/ Some images designed by Pixabay, licensed under Creative Commons Attribution 3.0 Unported License. Available from: https://pixabay.com/   Some images purchased from Shutterstock. Available from: https://www.shutterstock.com/ Some footage/images purchased from Storyblocks. Available from: https://www.storyblocks.com/ References: Efeyan A, Comb WC, Sabatini DM. Nutrient-sensing mechanisms and pathways. Nature. 2015;517(7534):302-10. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013;153(6):1194-217. Hoeijm https://www.youtube-nocookie.com/embed/xHlNXzfCv0o 835 2020-12-10T19:56:01.000Z 2026-10-22T17:43:40.172Z https://longevityharbor.com/de/watch/xHlNXzfCv0o The Biology of Aging https://i.ytimg.com/vi/xHlNXzfCv0o/hqdefault.jpg It is the greatest inevitability of life - aging. Have you ever wondered what happens within your body, that leads to its gradual decline in function and ultimately #aging? The longer we live, the more likely we are to develop age-related diseases; including cancer. In recent years, #science has taken big steps in understanding the biology of aging. Scientists have discovered nine biological hallmarks that contribute to the aging process. Here's how it works. More videos coming soon. Please rate☝️, comment👇, and subscribe☝️ if you like them, so that I can make more! Please send through requests for topics to cover as well. What do you want to learn about? #scienceinmotion   Check out other socials: TikTok - https://www.tiktok.com/@scienceinmotion Instagram - https://www.instagram.com/scienceinmotiongram/ Twitter - https://twitter.com/ScienceMotioner Facebook - https://www.facebook.com/Science-in-Motion-114470440455167 Website - https://scienceinmotion.wixsite.com/scienceinmotion Music thanks to:   Music by Adam Vitovský DOWNLOAD LINK: https://www.adamvitovsky.com/one-story Creative Commons — Attribution 3.0 Unported — CC BY 3.0   Images thanks to:   Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License.   Some images designed by Freepik/vectorpouch/pch.vector/vectorpocket . Available from: www.freepik.com Some images adapted from BioRender. Created with BioRender.com. Available from: https://biorender.com/ Some images designed by Pixabay, licensed under Creative Commons Attribution 3.0 Unported License. Available from: https://pixabay.com/   Some images purchased from Shutterstock. Available from: https://www.shutterstock.com/ Some footage/images purchased from Storyblocks. Available from: https://www.storyblocks.com/ References: Efeyan A, Comb WC, Sabatini DM. Nutrient-sensing mechanisms and pathways. Nature. 2015;517(7534):302-10. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013;153(6):1194-217. Hoeijm https://www.youtube-nocookie.com/embed/xHlNXzfCv0o 835 2020-12-10T19:56:01.000Z 2026-10-22T17:43:40.172Z https://longevityharbor.com/en/watch/xKKKGs72xOA Video description links mitochondrial decline to hallmarks of aging https://i.ytimg.com/vi/xKKKGs72xOA/hqdefault.jpg The description says Dr. V explains how declining mitochondrial function and cellular energy relate to the hallmarks of aging, fatigue, brain fog and chronic disease, and cites a Columbia and UCSF study on emotions and mitochondrial health. These are creator claims, not verified results. https://www.youtube-nocookie.com/embed/xKKKGs72xOA 376 2026-03-16T20:27:44.000Z 2026-10-23T02:05:15.353Z https://longevityharbor.com/de/watch/xKKKGs72xOA Videobeschreibung verknüpft Mitochondrienabbau mit Alternsmerkmalen https://i.ytimg.com/vi/xKKKGs72xOA/hqdefault.jpg Laut Beschreibung erklärt Dr. V, wie nachlassende Mitochondrienfunktion und zelluläre Energie mit Alternsmerkmalen, Fatigue, Brain Fog und chronischen Krankheiten zusammenhängen, und nennt eine Columbia- und UCSF-Studie zu Emotionen und Mitochondriengesundheit. Das sind Aussagen des Erstellers, keine geprüften Ergebnisse. https://www.youtube-nocookie.com/embed/xKKKGs72xOA 376 2026-03-16T20:27:44.000Z 2026-10-23T02:05:15.353Z https://longevityharbor.com/en/watch/xLmbHZyFP7k Longevity Supplement Ep.6 Minerals for longevity https://i.ytimg.com/vi/xLmbHZyFP7k/hqdefault.jpg ตอนนี้เล่าถึงวิตามินแร่ธาตุ ที่ช่วยในหลายกลไกใน Hallmarks of aging #Longevity #theLongevist #hallmarksofaging #หมออั๋น https://www.youtube-nocookie.com/embed/xLmbHZyFP7k 3577 2024-01-28T15:41:13.000Z 2026-10-22T19:54:19.301Z https://longevityharbor.com/de/watch/xLmbHZyFP7k Longevity Supplement Ep.6 Minerals for longevity https://i.ytimg.com/vi/xLmbHZyFP7k/hqdefault.jpg ตอนนี้เล่าถึงวิตามินแร่ธาตุ ที่ช่วยในหลายกลไกใน Hallmarks of aging #Longevity #theLongevist #hallmarksofaging #หมออั๋น https://www.youtube-nocookie.com/embed/xLmbHZyFP7k 3577 2024-01-28T15:41:13.000Z 2026-10-22T19:54:19.301Z https://longevityharbor.com/en/watch/xNz8s1qiziI Epigenetic Clocks and Anti-Aging Interventions with Brian Kennedy https://i.ytimg.com/vi/xNz8s1qiziI/hqdefault.jpg Can we bring the precision of modern medicine into the fight against aging? In this new episode of Decoding Longevity, host Macsue Jacques welcomes Prof. Brian Kennedy (National University of Singapore, Healthy Longevity Translation Research Program) to discuss the next frontier: aging clocks and personalized longevity strategies. 🔑 Key highlights: ✔️ LeanAge 2 Clock: a new biomarker tool that predicts biological aging and mortality risk. ✔️ Lipidomic (Dolly) Clock: how lipid changes reveal insights into cognitive decline and Alzheimer’s disease. ✔️ Why “one-size-fits-all” interventions don’t work in geroscience. ✔️ The dangers of combining supplements without clinical evidence. ✔️ How biological age measurement is moving into clinical trials and practice. This episode is perfect for anyone interested in longevity research, healthy aging, biomarkers, and the future of personalized health. 👉 Subscribe and share if you want to stay at the cutting edge of longevity science. https://www.youtube-nocookie.com/embed/xNz8s1qiziI 1767 2025-09-24T17:40:05.000Z 2026-10-22T17:43:35.242Z https://longevityharbor.com/de/watch/xNz8s1qiziI Epigenetic Clocks and Anti-Aging Interventions with Brian Kennedy https://i.ytimg.com/vi/xNz8s1qiziI/hqdefault.jpg Can we bring the precision of modern medicine into the fight against aging? In this new episode of Decoding Longevity, host Macsue Jacques welcomes Prof. Brian Kennedy (National University of Singapore, Healthy Longevity Translation Research Program) to discuss the next frontier: aging clocks and personalized longevity strategies. 🔑 Key highlights: ✔️ LeanAge 2 Clock: a new biomarker tool that predicts biological aging and mortality risk. ✔️ Lipidomic (Dolly) Clock: how lipid changes reveal insights into cognitive decline and Alzheimer’s disease. ✔️ Why “one-size-fits-all” interventions don’t work in geroscience. ✔️ The dangers of combining supplements without clinical evidence. ✔️ How biological age measurement is moving into clinical trials and practice. This episode is perfect for anyone interested in longevity research, healthy aging, biomarkers, and the future of personalized health. 👉 Subscribe and share if you want to stay at the cutting edge of longevity science. https://www.youtube-nocookie.com/embed/xNz8s1qiziI 1767 2025-09-24T17:40:05.000Z 2026-10-22T17:43:35.242Z https://longevityharbor.com/en/watch/xO-Ab8WsKxg Ancient Wisdom, Modern Science, and the Emerging Keys to Healthy Aging and Longevity https://i.ytimg.com/vi/xO-Ab8WsKxg/hqdefault.jpg Examine how what we eat and how we live can promote wellness, enhance immunity, combat age-related diseases, and promote longevity. Gordon Saxe, M.D., Ph.D., and Anthony Lim, M.D., J.D., share a timeless perspective, supported by their own research and clinical experience, on how optimal nourishment, purposeful reflection, health movement, and generosity of spirit can improve age-related conditions and slow the aging process. They present evidence-based recommendations for diet and lifestyle, as well as a practical and simple framework to help foster extending healthy aging behavioral changes. [12/2024] [Show ID: 40049] 0:00 Start 0:51 Gordon Saxe, M.D., Ph.D. 32:57 Anthony Lim, M.D., J.D. 1:02:24 Q&A Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/xO-Ab8WsKxg 5992 2024-11-27T03:00:47.000Z 2026-10-22T18:43:11.677Z https://longevityharbor.com/de/watch/xO-Ab8WsKxg Ancient Wisdom, Modern Science, and the Emerging Keys to Healthy Aging and Longevity https://i.ytimg.com/vi/xO-Ab8WsKxg/hqdefault.jpg Examine how what we eat and how we live can promote wellness, enhance immunity, combat age-related diseases, and promote longevity. Gordon Saxe, M.D., Ph.D., and Anthony Lim, M.D., J.D., share a timeless perspective, supported by their own research and clinical experience, on how optimal nourishment, purposeful reflection, health movement, and generosity of spirit can improve age-related conditions and slow the aging process. They present evidence-based recommendations for diet and lifestyle, as well as a practical and simple framework to help foster extending healthy aging behavioral changes. [12/2024] [Show ID: 40049] 0:00 Start 0:51 Gordon Saxe, M.D., Ph.D. 32:57 Anthony Lim, M.D., J.D. 1:02:24 Q&A Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: Stein Institute for Research on Aging (https://www.uctv.tv/stein) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) https://www.youtube-nocookie.com/embed/xO-Ab8WsKxg 5992 2024-11-27T03:00:47.000Z 2026-10-22T18:43:11.677Z https://longevityharbor.com/en/watch/xRhX5zrGfyg Can Science Help Us Age Better? Inside the Growing Field of Geroscience https://i.ytimg.com/vi/xRhX5zrGfyg/hqdefault.jpg What if aging itself is the biggest risk factor for diseases like Alzheimer’s, cancer, and heart disease? In this animated explainer, we break down *geroscience,* a growing field of research focused on _understanding the biology of aging_ and how slowing the aging process could help prevent multiple chronic diseases at once. Rather than treating Alzheimer’s or heart disease individually, geroscience asks a bigger question: what if we target aging itself? With populations aging worldwide, geroscience could reshape how we think about medicine, prevention, and longevity, not to help people live forever, but to help them live *healthier for longer.* This animation is designed for anyone curious about aging, longevity science, Alzheimer’s research, and the future of preventative medicine. https://www.youtube-nocookie.com/embed/xRhX5zrGfyg 146 2025-10-28T22:01:17.000Z 2026-10-22T17:43:40.190Z https://longevityharbor.com/de/watch/xRhX5zrGfyg Can Science Help Us Age Better? Inside the Growing Field of Geroscience https://i.ytimg.com/vi/xRhX5zrGfyg/hqdefault.jpg What if aging itself is the biggest risk factor for diseases like Alzheimer’s, cancer, and heart disease? In this animated explainer, we break down *geroscience,* a growing field of research focused on _understanding the biology of aging_ and how slowing the aging process could help prevent multiple chronic diseases at once. Rather than treating Alzheimer’s or heart disease individually, geroscience asks a bigger question: what if we target aging itself? With populations aging worldwide, geroscience could reshape how we think about medicine, prevention, and longevity, not to help people live forever, but to help them live *healthier for longer.* This animation is designed for anyone curious about aging, longevity science, Alzheimer’s research, and the future of preventative medicine. https://www.youtube-nocookie.com/embed/xRhX5zrGfyg 146 2025-10-28T22:01:17.000Z 2026-10-22T17:43:40.190Z https://longevityharbor.com/en/watch/xSV-VUfiibw Biologisches Alter: Was es dir verrät | Quarks https://i.ytimg.com/vi/xSV-VUfiibw/hqdefault.jpg Diese Methode beweist, was wir alle schon immer vermuten: Menschen altern ungleich schnell. Ein Tropfen Blut genügt und ein Labor kann daraus das biologische Alter bestimmen. Doch ist so ein Test wirklich sinnvoll? Ranga Yogeshwar findet es heraus. Autor: Jakob Kneser --- Danke fürs Zuschauen! Hat dir das Video gefallen? Dann abonniere jetzt den einzigen offiziellen Quarks-Kanal auf YouTube: https://www.youtube.com/Quarks?sub_confirmation=1 Quarks auf Facebook: https://www.facebook.com/quarks.de/ Besuche auch: https://www.quarks.de Quarks auf Instagram: https://www.instagram.com/quarks.de/ https://www.instagram.com/beautyquarks/ Hier gelangst du zum Clip in der WDR-Mediathek: https://www1.wdr.de/mediathek/video/sendungen/quarks-und-co/video-wie-alt-ist-ranga-wirklich-100.html https://www.youtube-nocookie.com/embed/xSV-VUfiibw 297 2018-06-26T14:09:09.000Z 2026-10-22T17:11:30.659Z https://longevityharbor.com/de/watch/xSV-VUfiibw Biologisches Alter: Was es dir verrät | Quarks https://i.ytimg.com/vi/xSV-VUfiibw/hqdefault.jpg Diese Methode beweist, was wir alle schon immer vermuten: Menschen altern ungleich schnell. Ein Tropfen Blut genügt und ein Labor kann daraus das biologische Alter bestimmen. Doch ist so ein Test wirklich sinnvoll? Ranga Yogeshwar findet es heraus. Autor: Jakob Kneser --- Danke fürs Zuschauen! Hat dir das Video gefallen? Dann abonniere jetzt den einzigen offiziellen Quarks-Kanal auf YouTube: https://www.youtube.com/Quarks?sub_confirmation=1 Quarks auf Facebook: https://www.facebook.com/quarks.de/ Besuche auch: https://www.quarks.de Quarks auf Instagram: https://www.instagram.com/quarks.de/ https://www.instagram.com/beautyquarks/ Hier gelangst du zum Clip in der WDR-Mediathek: https://www1.wdr.de/mediathek/video/sendungen/quarks-und-co/video-wie-alt-ist-ranga-wirklich-100.html https://www.youtube-nocookie.com/embed/xSV-VUfiibw 297 2018-06-26T14:09:09.000Z 2026-10-22T17:11:30.659Z https://longevityharbor.com/en/watch/xTRV49w0x4I Hilka de Groot "Gesund alt werden! Die Bedeutung von Ernährung, Bewegung und Sexualität" https://i.ytimg.com/vi/xTRV49w0x4I/hqdefault.jpg Hallo zusammen 👋 Willkommen zu einem weiteren Video Hilka de Groot "Gesund alt werden! Die Bedeutung von Ernährung, Bewegung und Sexualität" 📖 In diesem Vortrag stellt die bekannte Wissenschaftsjournalistin und Buchautorin Hilka de Groot die Bedeutung des eigenen Verhaltens für die Gesundheit im Alter in den Mittelpunkt. 👉 Wir lernen, wie 🍎 Ernährung, 🏃‍♀️ Bewegung und ❤️ Sexualität die Lebensqualität im Alter steigern kann. Frau de Groot liest auch längere Passagen aus ihrem Spiegel Bestseller „Gesund über 90 werden“, den sie gemeinsam mit Prof. Dr. Claus Leitzmann geschrieben hat. Im Anschluss gibt es eine lebhafte Diskussion. 🔗 Links: 📚 Bücher von Hilka de Groot: https://www.amazon.de/s?k=Hilka+de+Groot 🗂️ Programm und Archiv des Freitagsclubs: https://seniorentreff.de/blog/programm-und-archiv-der-online-vortraege-im-seniorentreff/1008156 🌐 Seniorentreff im Internet: https://seniorentreff.de 📺 Bitte abonniere kostenlos unseren YouTube-Kanal: 👉 https://www.youtube.com/seniorentreff?sub_confirmation=1 🔔✨ ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ Wenn Du neu auf unserem Kanal bist, freuen wir uns, dass Du auf unser Video geklickt hast! Ich hoffe, Dir gefällt das heutige Video. Bitte zeige Deine Unterstützung 🤝, indem Du jetzt der „Seniorentreff“-Community beitrittst, indem Du Dich anmeldest und die Glocke (🔔) drückst, um über neue Uploads benachrichtigt zu werden. Wenn Du Fragen oder Wünsche hast, hinterlasse gerne einen Kommentar unten. 🔴 𝐀𝐛𝐨𝐧𝐧𝐢𝐞𝐫𝐞 𝐮𝐧𝐬 𝐡𝐢𝐞𝐫: https://www.youtube.com/@seniorentreff/featured 👍 Like das Video (es hilft sehr!) 💬 Kommentiere unten, um Deine Meinung mitzuteilen! 🔗 Teile das Video mit allen, von denen Du glaubst, dass sie Interesse haben. ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ 🎬𝐕𝐎𝐑𝐆𝐄𝐒𝐂𝐇𝐋𝐀𝐆𝐄𝐍𝐄 𝐕𝐈𝐃𝐄𝐎𝐒 𝐅Ü𝐑 𝐃𝐈𝐂𝐇: Vergesse nicht, 📽 unsere anderen Videos anzuschauen. Bitte schaue Dir z. B. diese an: ▶️ 📖 MEMINTO ERKLÄRT:: GESCHICHTEN BEWAHREN, BEVOR ES ZU SPÄT IST ✅ https://youtu.be/bv3IkwcnY6c ▶️ 🤖 Künstliche Intelligenz erklärt: Wie DU sie privat nutzen kan https://www.youtube-nocookie.com/embed/xTRV49w0x4I 4582 2025-09-06T18:23:29.000Z 2026-10-22T19:43:44.120Z https://longevityharbor.com/de/watch/xTRV49w0x4I Hilka de Groot "Gesund alt werden! Die Bedeutung von Ernährung, Bewegung und Sexualität" https://i.ytimg.com/vi/xTRV49w0x4I/hqdefault.jpg Hallo zusammen 👋 Willkommen zu einem weiteren Video Hilka de Groot "Gesund alt werden! Die Bedeutung von Ernährung, Bewegung und Sexualität" 📖 In diesem Vortrag stellt die bekannte Wissenschaftsjournalistin und Buchautorin Hilka de Groot die Bedeutung des eigenen Verhaltens für die Gesundheit im Alter in den Mittelpunkt. 👉 Wir lernen, wie 🍎 Ernährung, 🏃‍♀️ Bewegung und ❤️ Sexualität die Lebensqualität im Alter steigern kann. Frau de Groot liest auch längere Passagen aus ihrem Spiegel Bestseller „Gesund über 90 werden“, den sie gemeinsam mit Prof. Dr. Claus Leitzmann geschrieben hat. Im Anschluss gibt es eine lebhafte Diskussion. 🔗 Links: 📚 Bücher von Hilka de Groot: https://www.amazon.de/s?k=Hilka+de+Groot 🗂️ Programm und Archiv des Freitagsclubs: https://seniorentreff.de/blog/programm-und-archiv-der-online-vortraege-im-seniorentreff/1008156 🌐 Seniorentreff im Internet: https://seniorentreff.de 📺 Bitte abonniere kostenlos unseren YouTube-Kanal: 👉 https://www.youtube.com/seniorentreff?sub_confirmation=1 🔔✨ ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ Wenn Du neu auf unserem Kanal bist, freuen wir uns, dass Du auf unser Video geklickt hast! Ich hoffe, Dir gefällt das heutige Video. Bitte zeige Deine Unterstützung 🤝, indem Du jetzt der „Seniorentreff“-Community beitrittst, indem Du Dich anmeldest und die Glocke (🔔) drückst, um über neue Uploads benachrichtigt zu werden. Wenn Du Fragen oder Wünsche hast, hinterlasse gerne einen Kommentar unten. 🔴 𝐀𝐛𝐨𝐧𝐧𝐢𝐞𝐫𝐞 𝐮𝐧𝐬 𝐡𝐢𝐞𝐫: https://www.youtube.com/@seniorentreff/featured 👍 Like das Video (es hilft sehr!) 💬 Kommentiere unten, um Deine Meinung mitzuteilen! 🔗 Teile das Video mit allen, von denen Du glaubst, dass sie Interesse haben. ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ 🎬𝐕𝐎𝐑𝐆𝐄𝐒𝐂𝐇𝐋𝐀𝐆𝐄𝐍𝐄 𝐕𝐈𝐃𝐄𝐎𝐒 𝐅Ü𝐑 𝐃𝐈𝐂𝐇: Vergesse nicht, 📽 unsere anderen Videos anzuschauen. Bitte schaue Dir z. B. diese an: ▶️ 📖 MEMINTO ERKLÄRT:: GESCHICHTEN BEWAHREN, BEVOR ES ZU SPÄT IST ✅ https://youtu.be/bv3IkwcnY6c ▶️ 🤖 Künstliche Intelligenz erklärt: Wie DU sie privat nutzen kan https://www.youtube-nocookie.com/embed/xTRV49w0x4I 4582 2025-09-06T18:23:29.000Z 2026-10-22T19:43:44.120Z https://longevityharbor.com/en/watch/xYvfDHcBffU Die besten Übungen für deinen Muskelaufbau im Alter! | Teil 1 https://i.ytimg.com/vi/xYvfDHcBffU/hqdefault.jpg Ja, im Alter ist das eine Sache mit den Muskelübungen: Die 100 Kilogramm auf der Bank sind gar nicht mal so einfach gedrückt. Doch was tun, welche Alternativen gibt es für Muskelaufbau im Alter? Das Video liefert die antworten dazu! Zum zweiten Teil gelangt ihr hier: https://youtu.be/PKK1eDnNsno Wollt ihr regelmäßig mit Infos zu den Themen Bewegung, Ernährung und Regeneration Fitness versorgt werden? Dann abonniert den Kanal: https://www.youtube.com/@formelfroboese __________ Formel Froböse Website: http://formel-froboese.de/ Formel Froböse auf Instagram: https://www.instagram.com/formel_froboese/ Ingo Froböse auf Facebook: https://www.facebook.com/IngoFroboese ___________ Ihr habt Hunger und wollt noch einen Nachschlag? Mehr zum Thema Ernährung findet ihr hier in der gesammelten Ernährungsplaylist: https://youtube.com/playlist?list=PLxC-D9Ac4VYNHYSlWfr_7QkQUsFUPaBT2 Der Bewegungsdrang lässt euch nicht los, aber ihr wollt noch mehr Infos, bevor es zum Sport geht? Hier findet ihr alles zu Bewegung & Sport: https://youtube.com/playlist?list=PLxC-D9Ac4VYN_ZB0Zd3IDJfjXOPY5U_Tl Ihr seid so richtig geschlaucht von Alltag, Sport und Stress? Dann schaut Mal in die Regenerationsplaylist rein: https://youtube.com/playlist?list=PLxC-D9Ac4VYMWRvBKNyJytaQ-JUf_WCgd ___________ Kapitel: 00:00 Einleitung 00:21 Übung 1 01:34 Übung 2 02:16 Übung 3 03:15 Übung 4 04:11 Übung 5 __________ #formelfroböse #ingofroböse #muskelübungen #training https://www.youtube-nocookie.com/embed/xYvfDHcBffU 300 2024-04-08T17:06:58.000Z 2026-10-22T17:43:36.063Z https://longevityharbor.com/de/watch/xYvfDHcBffU Die besten Übungen für deinen Muskelaufbau im Alter! | Teil 1 https://i.ytimg.com/vi/xYvfDHcBffU/hqdefault.jpg Ja, im Alter ist das eine Sache mit den Muskelübungen: Die 100 Kilogramm auf der Bank sind gar nicht mal so einfach gedrückt. Doch was tun, welche Alternativen gibt es für Muskelaufbau im Alter? Das Video liefert die antworten dazu! Zum zweiten Teil gelangt ihr hier: https://youtu.be/PKK1eDnNsno Wollt ihr regelmäßig mit Infos zu den Themen Bewegung, Ernährung und Regeneration Fitness versorgt werden? Dann abonniert den Kanal: https://www.youtube.com/@formelfroboese __________ Formel Froböse Website: http://formel-froboese.de/ Formel Froböse auf Instagram: https://www.instagram.com/formel_froboese/ Ingo Froböse auf Facebook: https://www.facebook.com/IngoFroboese ___________ Ihr habt Hunger und wollt noch einen Nachschlag? Mehr zum Thema Ernährung findet ihr hier in der gesammelten Ernährungsplaylist: https://youtube.com/playlist?list=PLxC-D9Ac4VYNHYSlWfr_7QkQUsFUPaBT2 Der Bewegungsdrang lässt euch nicht los, aber ihr wollt noch mehr Infos, bevor es zum Sport geht? Hier findet ihr alles zu Bewegung & Sport: https://youtube.com/playlist?list=PLxC-D9Ac4VYN_ZB0Zd3IDJfjXOPY5U_Tl Ihr seid so richtig geschlaucht von Alltag, Sport und Stress? Dann schaut Mal in die Regenerationsplaylist rein: https://youtube.com/playlist?list=PLxC-D9Ac4VYMWRvBKNyJytaQ-JUf_WCgd ___________ Kapitel: 00:00 Einleitung 00:21 Übung 1 01:34 Übung 2 02:16 Übung 3 03:15 Übung 4 04:11 Übung 5 __________ #formelfroböse #ingofroböse #muskelübungen #training https://www.youtube-nocookie.com/embed/xYvfDHcBffU 300 2024-04-08T17:06:58.000Z 2026-10-22T17:43:36.063Z https://longevityharbor.com/en/watch/x_DR2FgbLBo Diabetes beeinflusst unser biologisches Alter: Wie uns Krankheiten alt machen - Dr. Carsten Carlberg https://i.ytimg.com/vi/x_DR2FgbLBo/hqdefault.jpg Diabetes überwinden - Digitales Kongresspaket👉 https://digitalewelt.spitzen-praevention.com/kmm-diabetes/?utm_source=dw-produkt📃 ----------- Diabetes ist der Überbegriff für Erkrankungen, die mit der Dysregulation von Glukose- und Lipidhomeostase einhergehen. Typ 1 Diabetes (T1D) ist eine Autoimmunerkrankung, die innerhalb von Wochen bis Monaten die b-Zellen der Bauchspeicheldrüse zerstört (zumeist von Kindern und Jugendlichen) und die Insulinproduktion unmöglich macht. Sie macht jedoch weniger als 5% aller Diabetesfälle aus und basiert auf der Fehlfunktion von T Zellen des Immunsystems. Somit erklärt sich die genetische Prädisposition für T1D in erster Linie durch Variationen von Genen des Immunsystems. Darüber hinaus gibt es eine Reihe von monogenetischen Formen von Typ 2 Diabetes (T2D), die zusammengenommen jedoch nur 1-2% aller T2D Fälle repräsentieren. Hier sind im wesentlichen Gene von Transkriptionsfaktoren betroffen, die in b-Zellen wirken. Für die klassische polygenetische Form von T2D, die im Alter ab 40 Jahren auftritt, sind durch genomweite Assoziationsstudien (GWAS) mehr als 100 Gene bekannt, die in allen metabolischen Organen wirken. Das macht T2D zu einer sehr heterogenen Erkrankung, die eine personalisierte Behandlung auf der Basis des individuellen Genotyps der Patienten erfordert. Trotz umfangreicher Studien können bisher nur etwa 10% des Risiko an T2D zu erkranken durch genetischen Variationen, wie SNPs, erklärt werden. Das lässt die Vermutung zu, dass der Großteil der T2D Fälle eine epigenetische Ursache hat. Epigenetik betrifft die “Verpackung” der Gene innerhalb des Zellkerns mit Chromatin und bestimmt, ob ein Gen genutzt werden kann oder nicht. Epigenetik ist sehr dynamisch (Genetik dagegen nicht), d.h. sie reagiert sehr empfindlich auf Veränderungen im Lebensstil, wie Zusammensetzung unserer Nahrung, unser Gewicht und das Ausmaß an körperlicher Aktivität. Während der Embryonalphase zeigen sich die stärksten epigenetischen Effekte, wie z.B. in Reaktion auf Mangel- oder Fehlernährung in u https://www.youtube-nocookie.com/embed/x_DR2FgbLBo 565 2024-10-04T14:22:15.000Z 2026-10-22T17:11:30.663Z https://longevityharbor.com/de/watch/x_DR2FgbLBo Diabetes beeinflusst unser biologisches Alter: Wie uns Krankheiten alt machen - Dr. Carsten Carlberg https://i.ytimg.com/vi/x_DR2FgbLBo/hqdefault.jpg Diabetes überwinden - Digitales Kongresspaket👉 https://digitalewelt.spitzen-praevention.com/kmm-diabetes/?utm_source=dw-produkt📃 ----------- Diabetes ist der Überbegriff für Erkrankungen, die mit der Dysregulation von Glukose- und Lipidhomeostase einhergehen. Typ 1 Diabetes (T1D) ist eine Autoimmunerkrankung, die innerhalb von Wochen bis Monaten die b-Zellen der Bauchspeicheldrüse zerstört (zumeist von Kindern und Jugendlichen) und die Insulinproduktion unmöglich macht. Sie macht jedoch weniger als 5% aller Diabetesfälle aus und basiert auf der Fehlfunktion von T Zellen des Immunsystems. Somit erklärt sich die genetische Prädisposition für T1D in erster Linie durch Variationen von Genen des Immunsystems. Darüber hinaus gibt es eine Reihe von monogenetischen Formen von Typ 2 Diabetes (T2D), die zusammengenommen jedoch nur 1-2% aller T2D Fälle repräsentieren. Hier sind im wesentlichen Gene von Transkriptionsfaktoren betroffen, die in b-Zellen wirken. Für die klassische polygenetische Form von T2D, die im Alter ab 40 Jahren auftritt, sind durch genomweite Assoziationsstudien (GWAS) mehr als 100 Gene bekannt, die in allen metabolischen Organen wirken. Das macht T2D zu einer sehr heterogenen Erkrankung, die eine personalisierte Behandlung auf der Basis des individuellen Genotyps der Patienten erfordert. Trotz umfangreicher Studien können bisher nur etwa 10% des Risiko an T2D zu erkranken durch genetischen Variationen, wie SNPs, erklärt werden. Das lässt die Vermutung zu, dass der Großteil der T2D Fälle eine epigenetische Ursache hat. Epigenetik betrifft die “Verpackung” der Gene innerhalb des Zellkerns mit Chromatin und bestimmt, ob ein Gen genutzt werden kann oder nicht. Epigenetik ist sehr dynamisch (Genetik dagegen nicht), d.h. sie reagiert sehr empfindlich auf Veränderungen im Lebensstil, wie Zusammensetzung unserer Nahrung, unser Gewicht und das Ausmaß an körperlicher Aktivität. Während der Embryonalphase zeigen sich die stärksten epigenetischen Effekte, wie z.B. in Reaktion auf Mangel- oder Fehlernährung in u https://www.youtube-nocookie.com/embed/x_DR2FgbLBo 565 2024-10-04T14:22:15.000Z 2026-10-22T17:11:30.663Z https://longevityharbor.com/en/watch/xv3GwSNYJeM Video description: geroscience and rejuvenation claims explained https://i.ytimg.com/vi/xv3GwSNYJeM/hqdefault.jpg The description says the video contrasts evidence-based rejuvenation therapies with ineffective trends and explains why conventional medicine has been slow to focus on aging biology. https://www.youtube-nocookie.com/embed/xv3GwSNYJeM 445 2026-08-16T16:23:05.000Z 2026-10-22T22:58:20.977Z https://longevityharbor.com/de/watch/xv3GwSNYJeM Videobeschreibung: Geroscience und Verjüngungsversprechen erklärt https://i.ytimg.com/vi/xv3GwSNYJeM/hqdefault.jpg Laut Beschreibung vergleicht das Video belegte Verjüngungstherapien mit unwirksamen Trends und erklärt, warum die konventionelle Medizin die Biologie des Alterns lange wenig beachtet hat. https://www.youtube-nocookie.com/embed/xv3GwSNYJeM 445 2026-08-16T16:23:05.000Z 2026-10-22T22:58:20.977Z https://longevityharbor.com/en/watch/xxTUogH4GK4 What are senolytics (and should you be taking them)? https://i.ytimg.com/vi/xxTUogH4GK4/hqdefault.jpg These compounds are said to fight aging by clearing “zombie cells” out of your body. Is there any science to back this up? References Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial - PubMed (https://pubmed.ncbi.nlm.nih.gov/38956196/) A pilot study of senolytics to improve cognition and mobility in older adults at risk for Alzheimer’s disease - ScienceDirect (https://www.sciencedirect.com/science/article/pii/S2352396425000568) JCI - Strategies targeting cellular senescence (https://www.jci.org/articles/view/95149) Targeting senescent cells: approaches, opportunities, challenges - PMC (https://pmc.ncbi.nlm.nih.gov/articles/PMC6949083/) Targeting cellular senescence with senotherapeutics: senolytics and senomorphics - Zhang - 2023 - The FEBS Journal - Wiley Online Library (https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16350) New to Nutrition Diva? Check out our special Spotify playlist (https://open.spotify.com/playlist/59vwhJqu3bTvSCRsXmbqY6) for a collection of the best episodes curated by our team and Monica herself!  We've also curated some great playlists on specific episode topics including Staying Strong as We Age (https://open.spotify.com/playlist/1w4QoYhyNeiNXmG8i36n5r?si=fEPfi3EyR8SpTSGrOMCsWw) , Diabetes (https://open.spotify.com/playlist/4ElNfNcs5JNgFEKA9TCW1d) , Weight Loss That Lasts (https://open.spotify.com/playlist/5qNro1QNdnjz8BIUq8DA44?si=Wx4vacCtTzWFsCmYsJqQrg&nd=1&dlsi=cc716db299654817) and Gut Health (https://open.spotify.com/playlist/72UY4cxujSxcOcRiPflsyi) ! Also, find a playlist of our bone health series, Stronger Bones at Every Age (https://open.spotify.com/playlist/40l1EDvXS55Ar1YdN0dolA?si=nw7KfroLQq2LUqlkYydlkA) .  Have a nutrition question? Send an email to nutrition@quickanddirtytips.com. Follow Nutrition Diva on Facebook (https://facebook.com/qdtnutrition) and subscribe to the newsletter (https://www.quickanddirtytips.com/nutrition-diva-newsletter) for more diet and nu https://www.youtube-nocookie.com/embed/xxTUogH4GK4 575 2025-04-16T06:19:20.000Z 2026-10-22T19:21:23.324Z https://longevityharbor.com/de/watch/xxTUogH4GK4 What are senolytics (and should you be taking them)? https://i.ytimg.com/vi/xxTUogH4GK4/hqdefault.jpg These compounds are said to fight aging by clearing “zombie cells” out of your body. Is there any science to back this up? References Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial - PubMed (https://pubmed.ncbi.nlm.nih.gov/38956196/) A pilot study of senolytics to improve cognition and mobility in older adults at risk for Alzheimer’s disease - ScienceDirect (https://www.sciencedirect.com/science/article/pii/S2352396425000568) JCI - Strategies targeting cellular senescence (https://www.jci.org/articles/view/95149) Targeting senescent cells: approaches, opportunities, challenges - PMC (https://pmc.ncbi.nlm.nih.gov/articles/PMC6949083/) Targeting cellular senescence with senotherapeutics: senolytics and senomorphics - Zhang - 2023 - The FEBS Journal - Wiley Online Library (https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16350) New to Nutrition Diva? Check out our special Spotify playlist (https://open.spotify.com/playlist/59vwhJqu3bTvSCRsXmbqY6) for a collection of the best episodes curated by our team and Monica herself!  We've also curated some great playlists on specific episode topics including Staying Strong as We Age (https://open.spotify.com/playlist/1w4QoYhyNeiNXmG8i36n5r?si=fEPfi3EyR8SpTSGrOMCsWw) , Diabetes (https://open.spotify.com/playlist/4ElNfNcs5JNgFEKA9TCW1d) , Weight Loss That Lasts (https://open.spotify.com/playlist/5qNro1QNdnjz8BIUq8DA44?si=Wx4vacCtTzWFsCmYsJqQrg&nd=1&dlsi=cc716db299654817) and Gut Health (https://open.spotify.com/playlist/72UY4cxujSxcOcRiPflsyi) ! Also, find a playlist of our bone health series, Stronger Bones at Every Age (https://open.spotify.com/playlist/40l1EDvXS55Ar1YdN0dolA?si=nw7KfroLQq2LUqlkYydlkA) .  Have a nutrition question? Send an email to nutrition@quickanddirtytips.com. Follow Nutrition Diva on Facebook (https://facebook.com/qdtnutrition) and subscribe to the newsletter (https://www.quickanddirtytips.com/nutrition-diva-newsletter) for more diet and nu https://www.youtube-nocookie.com/embed/xxTUogH4GK4 575 2025-04-16T06:19:20.000Z 2026-10-22T19:21:23.324Z https://longevityharbor.com/en/watch/xywbRn_fE10 Reset Your Biological Age? The Science of the Fasting Mimicking Diet https://i.ytimg.com/vi/xywbRn_fE10/hqdefault.jpg What if you could turn back your biological clock without extreme dieting, pills, or biohacking gimmicks? In this premiere episode, we unpack the cutting-edge research behind the Fasting Mimicking Diet (FMD). Based on clinical trials from Dr. Valter Longo and others, we explore how this short-term, plant-based protocol can trigger deep cellular renewal, reduce visceral fat, improve metabolic health, and even rejuvenate the immune system. You’ll learn: • Why aging is more about your immune system than your wrinkles • How FMD mimics fasting without full deprivation • What biomarkers actually improved in human studies • The difference between chronological age and biological age • Risks, limitations, and how often to do it Whether you’re 40 or 70, curious or committed, this deep dive gives you the knowledge to think differently about longevity and healthspan. Let this be your gateway to informed, science-backed transformation. https://www.youtube-nocookie.com/embed/xywbRn_fE10 1025 2025-07-28T01:10:28.000Z 2026-10-22T19:54:18.192Z https://longevityharbor.com/de/watch/xywbRn_fE10 Reset Your Biological Age? The Science of the Fasting Mimicking Diet https://i.ytimg.com/vi/xywbRn_fE10/hqdefault.jpg What if you could turn back your biological clock without extreme dieting, pills, or biohacking gimmicks? In this premiere episode, we unpack the cutting-edge research behind the Fasting Mimicking Diet (FMD). Based on clinical trials from Dr. Valter Longo and others, we explore how this short-term, plant-based protocol can trigger deep cellular renewal, reduce visceral fat, improve metabolic health, and even rejuvenate the immune system. You’ll learn: • Why aging is more about your immune system than your wrinkles • How FMD mimics fasting without full deprivation • What biomarkers actually improved in human studies • The difference between chronological age and biological age • Risks, limitations, and how often to do it Whether you’re 40 or 70, curious or committed, this deep dive gives you the knowledge to think differently about longevity and healthspan. Let this be your gateway to informed, science-backed transformation. https://www.youtube-nocookie.com/embed/xywbRn_fE10 1025 2025-07-28T01:10:28.000Z 2026-10-22T19:54:18.192Z https://longevityharbor.com/en/watch/y-C_WA65uTE This DNA Test Says You're OLDER Than You Think (Epigenetic Clock Strikes Midnight) https://i.ytimg.com/vi/y-C_WA65uTE/hqdefault.jpg #EpigeneticClock #BiologicalAge #AntiAging #DNAMethylation #AgeReversal https://www.youtube-nocookie.com/embed/y-C_WA65uTE 248 2026-02-08T06:30:27.000Z 2026-10-22T19:21:27.630Z https://longevityharbor.com/de/watch/y-C_WA65uTE This DNA Test Says You're OLDER Than You Think (Epigenetic Clock Strikes Midnight) https://i.ytimg.com/vi/y-C_WA65uTE/hqdefault.jpg #EpigeneticClock #BiologicalAge #AntiAging #DNAMethylation #AgeReversal https://www.youtube-nocookie.com/embed/y-C_WA65uTE 248 2026-02-08T06:30:27.000Z 2026-10-22T19:21:27.630Z https://longevityharbor.com/en/watch/y1DLy5Zkrdw 6 Health Experts Reveal #1 Key to Aging Well, Burning Fat & Building Muscle Over 40 https://i.ytimg.com/vi/y1DLy5Zkrdw/hqdefault.jpg Want to live a longer, healthier life? It all starts with building and maintaining muscle. In this compilation episode of The Model Health Show, top experts like Mark Sisson, Dr. Gabrielle Lyon, and Dr. Andrew Huberman share powerful insights on why muscle matters — from boosting immunity and brain health to improving disease resilience and metabolism. Learn the science behind muscle-building and get practical strategies to do it efficiently. This episode is packed with tips to help you stay strong, functional, and healthy for life. Enjoy! Guest(s): Mark Sisson, Dr. Gabrielle Lyon, Alan Aragon, Dr. Andrew Huberman, JJ Virgin, Mark Bell. Subscribe: https://www.youtube.com/TheShawnModel?sub_confirmation=1 Watch more videos like this: INSTANTLY Boost Energy, Reduce Fatigue & SLEEP BETTER At Night! | Dr. Andrew Huberman: https://youtu.be/AXkESILHqm4 How To LOSE WEIGHT, Stay Young, & Be Fit Forever | JJ Virgin & Shawn Stevenson: https://youtu.be/avf1e3wt-dM Build Muscle Faster & Have Endless Exercise Motivation | Mark Bell & Shawn Stevenson: https://youtu.be/7oLBY9477ZE Build Muscle & Burn Fat Faster Over 40 with Jay Ferruggia: https://youtu.be/ZbfQeRp95e4 Playlist: https://www.youtube.com/playlist?list=PL3zvw5sD7WKyUHLrE3d9x_fRBnOPxqmM- Timestamps: 00:00 - Introduction 00:43 - How Muscle Helps you Live Longer 07:32 - Why Muscle is the Organ of Longevity 18:43 - Muscle is the Metabolic Engine of the Body 22:40 - How Strength Training Makes You Smarter 28:02 - Focus on Muscle First 35:19 - More Ways to Use Your Muscles for Longevity Shawn Stevenson is the author of the USA Today National bestsellers Eat Smarter and the Eat Smarter Family Cookbook, as well as the international bestselling book Sleep Smarter. He’s also the creator of The Model Health Show, featured as the number #1 health podcast in the U.S. with millions of listener downloads each year. A graduate of the University of Missouri–St. Louis, Shawn studied business, biology, and nutritional science and became the cofounder of Advanced Integrative Heal https://www.youtube-nocookie.com/embed/y1DLy5Zkrdw 3227 2025-04-17T12:01:47.000Z 2026-10-22T19:43:45.400Z https://longevityharbor.com/de/watch/y1DLy5Zkrdw 6 Health Experts Reveal #1 Key to Aging Well, Burning Fat & Building Muscle Over 40 https://i.ytimg.com/vi/y1DLy5Zkrdw/hqdefault.jpg Want to live a longer, healthier life? It all starts with building and maintaining muscle. In this compilation episode of The Model Health Show, top experts like Mark Sisson, Dr. Gabrielle Lyon, and Dr. Andrew Huberman share powerful insights on why muscle matters — from boosting immunity and brain health to improving disease resilience and metabolism. Learn the science behind muscle-building and get practical strategies to do it efficiently. This episode is packed with tips to help you stay strong, functional, and healthy for life. Enjoy! Guest(s): Mark Sisson, Dr. Gabrielle Lyon, Alan Aragon, Dr. Andrew Huberman, JJ Virgin, Mark Bell. Subscribe: https://www.youtube.com/TheShawnModel?sub_confirmation=1 Watch more videos like this: INSTANTLY Boost Energy, Reduce Fatigue & SLEEP BETTER At Night! | Dr. Andrew Huberman: https://youtu.be/AXkESILHqm4 How To LOSE WEIGHT, Stay Young, & Be Fit Forever | JJ Virgin & Shawn Stevenson: https://youtu.be/avf1e3wt-dM Build Muscle Faster & Have Endless Exercise Motivation | Mark Bell & Shawn Stevenson: https://youtu.be/7oLBY9477ZE Build Muscle & Burn Fat Faster Over 40 with Jay Ferruggia: https://youtu.be/ZbfQeRp95e4 Playlist: https://www.youtube.com/playlist?list=PL3zvw5sD7WKyUHLrE3d9x_fRBnOPxqmM- Timestamps: 00:00 - Introduction 00:43 - How Muscle Helps you Live Longer 07:32 - Why Muscle is the Organ of Longevity 18:43 - Muscle is the Metabolic Engine of the Body 22:40 - How Strength Training Makes You Smarter 28:02 - Focus on Muscle First 35:19 - More Ways to Use Your Muscles for Longevity Shawn Stevenson is the author of the USA Today National bestsellers Eat Smarter and the Eat Smarter Family Cookbook, as well as the international bestselling book Sleep Smarter. He’s also the creator of The Model Health Show, featured as the number #1 health podcast in the U.S. with millions of listener downloads each year. A graduate of the University of Missouri–St. Louis, Shawn studied business, biology, and nutritional science and became the cofounder of Advanced Integrative Heal https://www.youtube-nocookie.com/embed/y1DLy5Zkrdw 3227 2025-04-17T12:01:47.000Z 2026-10-22T19:43:45.400Z https://longevityharbor.com/en/watch/y3gidy0fva8 Wie gesund ist vegane Ernährung? https://i.ytimg.com/vi/y3gidy0fva8/hqdefault.jpg Wie gesund ist eine vegane Ernährung? In diesem Video reagieren der Mediziner Maximilian Huttasch und der Ernährungswissenschaftler Niko Rittenau auf einen Beitrag des MDR über den Senioren Friedhelm Wegner, der kürzlich 90 Jahre alt wurde, bereits seit über 60 Jahren vegan lebt und seinem Alter entsprechend bei guter Gesundheit ist. Seither kursiert dieses Video in der veganen Bewegung und wird als Argument herangezogen, dass sich jede Person vegan ernähren kann und man damit sogar bis ins hohe Alter hinein gesund bleibt. Warum ein einzelner Fallbericht nur eine sehr begrenzte Aussagekraft aufweist und was die wissenschaftliche Daten zu veganer Ernährung zeigen, wird in diesem Video besprochen. Wenn man sich vegan ernähren möchte, sollte man Augenmerk auf die Kompensation jener Nährstoffe legen, die man überwiegend oder ausschließlich in tierischen Lebensmitteln findet. Laut der Deutschen Gesellschaft für Ernährung (DGE) sowie der ‘Academy of Nutrition and Dietetics’ (AND) in den USA sind folgende Nährstoffe kritisch: Vitamin A, B12, B2, Jod, Selen, Eisen, Zink, Calcium, das Vitaminoid Cholin sowie die Omega-3-Fettsäuren EPA und DHA. Darüber hinaus kann laut DGE und AND die Proteinzufuhr allgemein bzw. die Zufuhr gewisser Aminosäuren wie Lysin bei veganer Ernährung kritisch sein. In der wissenschaftlichen Datenlage finden sich darüber hinaus Hinweise darauf, dass die Bedarfsdeckung mit weiteren Nährstoffen wie Arachidonsäure (ARA), Kreatin, Carnitin, Taurin, Carnosin und weitere Carninutrients - vor allem in Phasen des erhöhten Bedarfs wie der Schwangerschaft, Stillzeit und dem Kindesalter - oft nicht ausreichend stattfindet. Der einfachste Weg zur Kompensation dieser kritischen Nährstoffe ist ein auf vegane Ernährung zugeschnittener, laborgeprüfter Multinährstoff sowie ein passendes Algen-Pilz-Öl für EPA, DHA und ARA sowie eine ausgewogene Kostzusammenstellung auf Basis der pflanzlichen Hauptlebensmittelgruppen Vollkorngetreide, Hülsenfrüchte, Gemüse, Obst, Nüsse und Saaten mit einem Fokus auf einer ausre https://www.youtube-nocookie.com/embed/y3gidy0fva8 178 2025-11-07T08:05:39.000Z 2026-10-22T19:43:44.376Z https://longevityharbor.com/de/watch/y3gidy0fva8 Wie gesund ist vegane Ernährung? https://i.ytimg.com/vi/y3gidy0fva8/hqdefault.jpg Wie gesund ist eine vegane Ernährung? In diesem Video reagieren der Mediziner Maximilian Huttasch und der Ernährungswissenschaftler Niko Rittenau auf einen Beitrag des MDR über den Senioren Friedhelm Wegner, der kürzlich 90 Jahre alt wurde, bereits seit über 60 Jahren vegan lebt und seinem Alter entsprechend bei guter Gesundheit ist. Seither kursiert dieses Video in der veganen Bewegung und wird als Argument herangezogen, dass sich jede Person vegan ernähren kann und man damit sogar bis ins hohe Alter hinein gesund bleibt. Warum ein einzelner Fallbericht nur eine sehr begrenzte Aussagekraft aufweist und was die wissenschaftliche Daten zu veganer Ernährung zeigen, wird in diesem Video besprochen. Wenn man sich vegan ernähren möchte, sollte man Augenmerk auf die Kompensation jener Nährstoffe legen, die man überwiegend oder ausschließlich in tierischen Lebensmitteln findet. Laut der Deutschen Gesellschaft für Ernährung (DGE) sowie der ‘Academy of Nutrition and Dietetics’ (AND) in den USA sind folgende Nährstoffe kritisch: Vitamin A, B12, B2, Jod, Selen, Eisen, Zink, Calcium, das Vitaminoid Cholin sowie die Omega-3-Fettsäuren EPA und DHA. Darüber hinaus kann laut DGE und AND die Proteinzufuhr allgemein bzw. die Zufuhr gewisser Aminosäuren wie Lysin bei veganer Ernährung kritisch sein. In der wissenschaftlichen Datenlage finden sich darüber hinaus Hinweise darauf, dass die Bedarfsdeckung mit weiteren Nährstoffen wie Arachidonsäure (ARA), Kreatin, Carnitin, Taurin, Carnosin und weitere Carninutrients - vor allem in Phasen des erhöhten Bedarfs wie der Schwangerschaft, Stillzeit und dem Kindesalter - oft nicht ausreichend stattfindet. Der einfachste Weg zur Kompensation dieser kritischen Nährstoffe ist ein auf vegane Ernährung zugeschnittener, laborgeprüfter Multinährstoff sowie ein passendes Algen-Pilz-Öl für EPA, DHA und ARA sowie eine ausgewogene Kostzusammenstellung auf Basis der pflanzlichen Hauptlebensmittelgruppen Vollkorngetreide, Hülsenfrüchte, Gemüse, Obst, Nüsse und Saaten mit einem Fokus auf einer ausre https://www.youtube-nocookie.com/embed/y3gidy0fva8 178 2025-11-07T08:05:39.000Z 2026-10-22T19:43:44.376Z https://longevityharbor.com/en/watch/y5PKU3X4TUo Gesund essen? Die Wahrheit über die Ernährungsempfehlungen der DGE | Quarks Studio Q https://i.ytimg.com/vi/y5PKU3X4TUo/hqdefault.jpg Wie geht gesunde Ernährung? Die Deutsche Gesellschaft für Ernährung (DGE) gibt darauf eine klare Antwort und versorgte uns dieses Jahr mit neuen Empfehlungen zu gesunden Lebensmitteln, die nicht nur für Kantinen und Krankenhäuser, sondern auch für jeden Einzelnen relevant sind. Aber wie gesund sind die Ernährungsempfehlungen der DGE wirklich? Bis zu 300 Gramm Fleisch pro Woche empfiehlt die DGE. Ist das zuviel? Immerhin spielt bei den DGE-Empfehlungen nicht nur die Gesundheit eine Rolle, sondern auch die Umwelt. Wären pflanzliche Lebensmittel wie Hülsenfrüchte am Ende nicht gesünder und dazu klimafreundlicher? Wieso die DGE trotzdem nicht weniger Fleisch empfiehlt, erfahrt ihr im Video. Eine weitere Kritik: Die DGE-Empfehlungen richten sich vor allem an gesunde Erwachsene. Und die machen in Deutschland weniger als die Hälfte der Bevölkerung aus. Schließlich gibt es viele Menschen mit Diabetes, Übergewicht und anderen Vorerkrankungen oder Lebensmittel-Allergien. Und was ist mit Kindern, Jugendlichen, Schwangeren und Senioren, die ebenfalls besondere Nährstoffzusammensetzungen benötigen. // Kapitel 0:00 Sind die DGE-Empfehlungen ungesund? 0:40 Was ist eigentlich gesundes Essen? 3:18 Was empfiehlt die DGE? - Auch das Klima spielt dabei eine Rolle 5:18 Warum nicht noch weniger Fleisch und mehr Hülsenfrüchte? 8:29 Solltest du dich an die Empfehlungen halten? - Kritik am Ernährungskreis // Unser Team Autor: Mathias Tertilt Kamera und Schnitt: Carolin Grimm Grafik: Judith Bornmann Redaktion: Max Ostendorf // Hier geht's zum Quellendokument https://docs.google.com/document/d/1dPm1buVK9HE5h7RuFDdUOGOpNGnV143KKmCseHeU9jk // Mehr zum Thema Noch mehr Informationen und Einordnung zur DGE und den Empfehlungen gibt es auf quarks.de: https://www.quarks.de/gesundheit/ernaehrung/dge-empfehlung/ Warum Ernährungsstudien tricky sind, erfährst du auf quarks.de: https://www.quarks.de/gesundheit/darum-solltest-du-nicht-jeder-studie-glauben/ Vegan ist nicht automatisch gesund - Was du beachten solltest, erzähle https://www.youtube-nocookie.com/embed/y5PKU3X4TUo 670 2024-11-08T08:32:00.000Z 2026-10-22T19:04:43.925Z https://longevityharbor.com/de/watch/y5PKU3X4TUo Gesund essen? Die Wahrheit über die Ernährungsempfehlungen der DGE | Quarks Studio Q https://i.ytimg.com/vi/y5PKU3X4TUo/hqdefault.jpg Wie geht gesunde Ernährung? Die Deutsche Gesellschaft für Ernährung (DGE) gibt darauf eine klare Antwort und versorgte uns dieses Jahr mit neuen Empfehlungen zu gesunden Lebensmitteln, die nicht nur für Kantinen und Krankenhäuser, sondern auch für jeden Einzelnen relevant sind. Aber wie gesund sind die Ernährungsempfehlungen der DGE wirklich? Bis zu 300 Gramm Fleisch pro Woche empfiehlt die DGE. Ist das zuviel? Immerhin spielt bei den DGE-Empfehlungen nicht nur die Gesundheit eine Rolle, sondern auch die Umwelt. Wären pflanzliche Lebensmittel wie Hülsenfrüchte am Ende nicht gesünder und dazu klimafreundlicher? Wieso die DGE trotzdem nicht weniger Fleisch empfiehlt, erfahrt ihr im Video. Eine weitere Kritik: Die DGE-Empfehlungen richten sich vor allem an gesunde Erwachsene. Und die machen in Deutschland weniger als die Hälfte der Bevölkerung aus. Schließlich gibt es viele Menschen mit Diabetes, Übergewicht und anderen Vorerkrankungen oder Lebensmittel-Allergien. Und was ist mit Kindern, Jugendlichen, Schwangeren und Senioren, die ebenfalls besondere Nährstoffzusammensetzungen benötigen. // Kapitel 0:00 Sind die DGE-Empfehlungen ungesund? 0:40 Was ist eigentlich gesundes Essen? 3:18 Was empfiehlt die DGE? - Auch das Klima spielt dabei eine Rolle 5:18 Warum nicht noch weniger Fleisch und mehr Hülsenfrüchte? 8:29 Solltest du dich an die Empfehlungen halten? - Kritik am Ernährungskreis // Unser Team Autor: Mathias Tertilt Kamera und Schnitt: Carolin Grimm Grafik: Judith Bornmann Redaktion: Max Ostendorf // Hier geht's zum Quellendokument https://docs.google.com/document/d/1dPm1buVK9HE5h7RuFDdUOGOpNGnV143KKmCseHeU9jk // Mehr zum Thema Noch mehr Informationen und Einordnung zur DGE und den Empfehlungen gibt es auf quarks.de: https://www.quarks.de/gesundheit/ernaehrung/dge-empfehlung/ Warum Ernährungsstudien tricky sind, erfährst du auf quarks.de: https://www.quarks.de/gesundheit/darum-solltest-du-nicht-jeder-studie-glauben/ Vegan ist nicht automatisch gesund - Was du beachten solltest, erzähle https://www.youtube-nocookie.com/embed/y5PKU3X4TUo 670 2024-11-08T08:32:00.000Z 2026-10-22T19:04:43.925Z https://longevityharbor.com/en/watch/y739v6h_low Fasting and biological aging: what a video description says it covers https://i.ytimg.com/vi/y739v6h_low/hqdefault.jpg The description says the video asks whether fasting can slow or reverse biological aging and discusses autophagy, ketones, cellular clean-up and human evidence, citing a reported 2.5-year reduction in a median biological age measurement. The video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/y739v6h_low 499 2026-10-10T15:04:58.000Z 2026-10-22T20:27:51.917Z https://longevityharbor.com/de/watch/y739v6h_low Fasten und biologisches Altern: Was eine Videobeschreibung laut eigener Angabe behandelt https://i.ytimg.com/vi/y739v6h_low/hqdefault.jpg Laut Beschreibung fragt das Video, ob Fasten biologisches Altern verlangsamen oder rückgängig machen kann, und behandelt Autophagie, Ketone, zelluläre Aufräumprozesse und menschliche Evidenz, mit einem berichteten Rückgang einer medianen biologischen Altersmessung um 2,5 Jahre. Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/y739v6h_low 499 2026-10-10T15:04:58.000Z 2026-10-22T20:27:51.917Z https://longevityharbor.com/en/watch/y7_y_VKh1QU Rapamycin from Easter Island: described anti-aging research https://i.ytimg.com/vi/y7_y_VKh1QU/hqdefault.jpg The description says rapamycin, originally from Easter Island, was found to slow cell division and is now studied for possibly slowing aging and delaying age-related diseases by inhibiting mTOR. https://www.youtube-nocookie.com/embed/y7_y_VKh1QU 179 2026-07-16T23:32:41.000Z 2026-10-22T23:30:11.842Z https://longevityharbor.com/de/watch/y7_y_VKh1QU Rapamycin von der Osterinsel: beschriebene Alternsforschung https://i.ytimg.com/vi/y7_y_VKh1QU/hqdefault.jpg Laut Beschreibung wurde Rapamycin, ursprünglich von der Osterinsel, dabei entdeckt, die Zellteilung zu verlangsamen; heute wird es daraufhin untersucht, ob es durch Hemmung von mTOR das Altern verlangsamen und altersbezogene Krankheiten verzögern könnte. https://www.youtube-nocookie.com/embed/y7_y_VKh1QU 179 2026-07-16T23:32:41.000Z 2026-10-22T23:30:11.842Z https://longevityharbor.com/en/watch/yBKDp9CHdLk MITs 7-Minuten-„Fasten-Atem“ löst Autophagie aus (Keine Diät erforderlich) https://i.ytimg.com/vi/yBKDp9CHdLk/hqdefault.jpg #Autophagie #FastenAtem #MIT Entdecken Sie, wie die 7-minütige „Fasten-Atem“-Technik des MIT die Autophagie auslöst, ohne dass eine strenge Diät erforderlich ist. Diese revolutionäre Atemübung hilft, Ihre Zellen zu reinigen und Ihre Langlebigkeit auf natürliche Weise zu fördern. In diesem Video tauchen wir tief in die Wissenschaft hinter dem von Forschern entwickelten 7-minütigen Fasten-Atem ein. Erfahren Sie, wie kontrollierte Atemmuster die Vorteile des intermittierenden Fastens nachahmen können. Wir erklären den Schritt-für-Schritt-Prozess, damit Sie die Zellerneuerung täglich ganz einfach aktivieren können. Abonnieren Sie unseren Kanal für weitere wissenschaftlich fundierte Gesundheits- und Wellness-Tipps! #Zellerneuerung #IntermittierendesFasten #Atemuebungen #Langlebigkeit #GesundLeben https://www.youtube-nocookie.com/embed/yBKDp9CHdLk 785 2026-08-13T17:00:29.000Z 2026-10-22T18:32:09.032Z https://longevityharbor.com/de/watch/yBKDp9CHdLk MITs 7-Minuten-„Fasten-Atem“ löst Autophagie aus (Keine Diät erforderlich) https://i.ytimg.com/vi/yBKDp9CHdLk/hqdefault.jpg #Autophagie #FastenAtem #MIT Entdecken Sie, wie die 7-minütige „Fasten-Atem“-Technik des MIT die Autophagie auslöst, ohne dass eine strenge Diät erforderlich ist. Diese revolutionäre Atemübung hilft, Ihre Zellen zu reinigen und Ihre Langlebigkeit auf natürliche Weise zu fördern. In diesem Video tauchen wir tief in die Wissenschaft hinter dem von Forschern entwickelten 7-minütigen Fasten-Atem ein. Erfahren Sie, wie kontrollierte Atemmuster die Vorteile des intermittierenden Fastens nachahmen können. Wir erklären den Schritt-für-Schritt-Prozess, damit Sie die Zellerneuerung täglich ganz einfach aktivieren können. Abonnieren Sie unseren Kanal für weitere wissenschaftlich fundierte Gesundheits- und Wellness-Tipps! #Zellerneuerung #IntermittierendesFasten #Atemuebungen #Langlebigkeit #GesundLeben https://www.youtube-nocookie.com/embed/yBKDp9CHdLk 785 2026-08-13T17:00:29.000Z 2026-10-22T18:32:09.032Z https://longevityharbor.com/en/watch/yDmvjq4Pjus Epigenetic clocks: DNA tags used to estimate biological age https://i.ytimg.com/vi/yDmvjq4Pjus/hqdefault.jpg The description says epigenetic clocks read chemical tags on DNA to estimate biological age, which may differ from chronological age; it credits Horvath's 2013 clock and later tools such as GrimAge and DunedinPACE. https://www.youtube-nocookie.com/embed/yDmvjq4Pjus 282 2026-07-20T08:00:26.000Z 2026-10-22T23:28:02.540Z https://longevityharbor.com/de/watch/yDmvjq4Pjus Epigenetische Uhren: DNA-Markierungen zur Schätzung des biologischen Alters https://i.ytimg.com/vi/yDmvjq4Pjus/hqdefault.jpg Laut Beschreibung lesen epigenetische Uhren chemische Markierungen auf der DNA, um das biologische Alter zu schätzen, das vom chronologischen Alter abweichen kann; genannt werden Horvaths Uhr von 2013 und spätere Werkzeuge wie GrimAge und DunedinPACE. https://www.youtube-nocookie.com/embed/yDmvjq4Pjus 282 2026-07-20T08:00:26.000Z 2026-10-22T23:28:02.540Z https://longevityharbor.com/en/watch/yFO20NIEAlo So geht eiweißreiche Ernährung: Warum der Proteinbedarf im Alter steigt I ARD Gesund https://i.ytimg.com/vi/yFO20NIEAlo/hqdefault.jpg Ein Film des NDR. Proteine sind unter anderem ein wichtiger Nährstoff für den Erhalt und den Aufbau der Muskeln. Ohne das Eiweiß drohen Muskel-, Kraft- und Funktionsverlust. Im Alter sinkt der Kalorienbedarf zwar um ein Viertel, der Proteinbedarf dagegen steigt deutlich an. Der Grund: Muskeln bauen im Alter schneller ab und Entzündungsprozesse, z.B. durch chronische Krankheiten, steigern den Bedarf an Eiweißen zusätzlich. Eine proteinreiche Ernährung sowie Krafttraining können dem entgegenwirken. Wie hoch muss die Eiweißzufuhr in welchem Alter jedoch sein? Ist tierisches oder pflanzliches Eiweiß sinnvoller und sind Nahrungsergänzungsmittel eine Alternative? Das erfahren Sie in der Visite. 00:00 Wie entsteht ein Proteinmangel? 02:00 Wofür brauchen wir Proteine? 03:15 Pflanzliche und tierische Proteine 05:50 Wer sollte bei zu hoher Eiweißaufnahme aufpassen? 06:30 So kann man seine Proteinmenge steigern Autor: Niels Walker Redaktion: Renate Schüssler Kamera: C. Janssen, D. Sealand Schnitt: Benjamin Jakobs Grafik: Andreas Werner Expertin und Experte aus dem Beitrag: Alina Kistenmacher Ökotrophologin und zertifizierte Ernährungstherapeutin, Lübeck Dr. Martin Willkomm, Facharzt für innere Medizin und Chefarzt Geesthacht Mehr Infos zum Thema Proteine findet ihr hier: https://www.ndr.de/ratgeber/gesundheit/Wie-viel-Eiweiss-ist-gesund,eiweiss102.html Und noch mehr spannende Dokus & Reportagen über das Gesundsein und Gesundbleiben findet ihr in der ARD Mediathek: https://www.ardmediathek.de/gesundheit ___________________________________________________ ARD GESUND mit Dr. Julia Fischer ist ein YouTube-Kanal von ARD GESUND https://www.youtube-nocookie.com/embed/yFO20NIEAlo 437 2025-11-24T15:02:06.000Z 2026-10-22T18:43:10.844Z https://longevityharbor.com/de/watch/yFO20NIEAlo So geht eiweißreiche Ernährung: Warum der Proteinbedarf im Alter steigt I ARD Gesund https://i.ytimg.com/vi/yFO20NIEAlo/hqdefault.jpg Ein Film des NDR. Proteine sind unter anderem ein wichtiger Nährstoff für den Erhalt und den Aufbau der Muskeln. Ohne das Eiweiß drohen Muskel-, Kraft- und Funktionsverlust. Im Alter sinkt der Kalorienbedarf zwar um ein Viertel, der Proteinbedarf dagegen steigt deutlich an. Der Grund: Muskeln bauen im Alter schneller ab und Entzündungsprozesse, z.B. durch chronische Krankheiten, steigern den Bedarf an Eiweißen zusätzlich. Eine proteinreiche Ernährung sowie Krafttraining können dem entgegenwirken. Wie hoch muss die Eiweißzufuhr in welchem Alter jedoch sein? Ist tierisches oder pflanzliches Eiweiß sinnvoller und sind Nahrungsergänzungsmittel eine Alternative? Das erfahren Sie in der Visite. 00:00 Wie entsteht ein Proteinmangel? 02:00 Wofür brauchen wir Proteine? 03:15 Pflanzliche und tierische Proteine 05:50 Wer sollte bei zu hoher Eiweißaufnahme aufpassen? 06:30 So kann man seine Proteinmenge steigern Autor: Niels Walker Redaktion: Renate Schüssler Kamera: C. Janssen, D. Sealand Schnitt: Benjamin Jakobs Grafik: Andreas Werner Expertin und Experte aus dem Beitrag: Alina Kistenmacher Ökotrophologin und zertifizierte Ernährungstherapeutin, Lübeck Dr. Martin Willkomm, Facharzt für innere Medizin und Chefarzt Geesthacht Mehr Infos zum Thema Proteine findet ihr hier: https://www.ndr.de/ratgeber/gesundheit/Wie-viel-Eiweiss-ist-gesund,eiweiss102.html Und noch mehr spannende Dokus & Reportagen über das Gesundsein und Gesundbleiben findet ihr in der ARD Mediathek: https://www.ardmediathek.de/gesundheit ___________________________________________________ ARD GESUND mit Dr. Julia Fischer ist ein YouTube-Kanal von ARD GESUND https://www.youtube-nocookie.com/embed/yFO20NIEAlo 437 2025-11-24T15:02:06.000Z 2026-10-22T18:43:10.844Z https://longevityharbor.com/en/watch/yKifVyGud4c Dr. Steve Horvath Interview of Epigenetic Clock by Dr. Min Seob Lee https://i.ytimg.com/vi/yKifVyGud4c/hqdefault.jpg Title: Revealing the Secrets of the Horvath Clock — Dr. Steve Horvath & Dr. Min Seob Lee (EDGC) Description: In this exclusive interview, Dr. Min Seob Lee, CEO of EDGC, sits down with Dr. Steve Horvath, the world-renowned scientist behind the Horvath Epigenetic Clock — one of the most groundbreaking discoveries in aging research. Dr. Horvath shares how DNA methylation patterns can precisely measure biological age across all human tissues and even multiple mammalian species. He explains why he sees aging as a continuation of development, how his 2013 epigenetic clock achieved unmatched accuracy, and where the future of longevity science is headed. From anti-aging human trials to pan-mammalian clocks, this conversation explores how cutting-edge science can inspire healthier lifestyles, predict disease risk, and potentially reverse aspects of aging. Dr. Horvath also reveals his personal longevity routine — from daily exercise and a plant-rich diet to supplements and sleep habits. Key topics in this interview: The science and accuracy of the Horvath Clock Why DNA methylation is the most versatile aging biomarker Breakthroughs in reversing biological age Future applications for humans and companion animals South Korea’s unique role in global longevity research Dr. Horvath’s own anti-aging practices Whether you’re a researcher, health enthusiast, or simply curious about the future of aging science, this interview offers rare insight from one of the field’s most influential figures. https://www.youtube-nocookie.com/embed/yKifVyGud4c 1637 2025-08-12T14:31:24.000Z 2026-10-22T18:54:04.135Z https://longevityharbor.com/de/watch/yKifVyGud4c Dr. Steve Horvath Interview of Epigenetic Clock by Dr. Min Seob Lee https://i.ytimg.com/vi/yKifVyGud4c/hqdefault.jpg Title: Revealing the Secrets of the Horvath Clock — Dr. Steve Horvath & Dr. Min Seob Lee (EDGC) Description: In this exclusive interview, Dr. Min Seob Lee, CEO of EDGC, sits down with Dr. Steve Horvath, the world-renowned scientist behind the Horvath Epigenetic Clock — one of the most groundbreaking discoveries in aging research. Dr. Horvath shares how DNA methylation patterns can precisely measure biological age across all human tissues and even multiple mammalian species. He explains why he sees aging as a continuation of development, how his 2013 epigenetic clock achieved unmatched accuracy, and where the future of longevity science is headed. From anti-aging human trials to pan-mammalian clocks, this conversation explores how cutting-edge science can inspire healthier lifestyles, predict disease risk, and potentially reverse aspects of aging. Dr. Horvath also reveals his personal longevity routine — from daily exercise and a plant-rich diet to supplements and sleep habits. Key topics in this interview: The science and accuracy of the Horvath Clock Why DNA methylation is the most versatile aging biomarker Breakthroughs in reversing biological age Future applications for humans and companion animals South Korea’s unique role in global longevity research Dr. Horvath’s own anti-aging practices Whether you’re a researcher, health enthusiast, or simply curious about the future of aging science, this interview offers rare insight from one of the field’s most influential figures. https://www.youtube-nocookie.com/embed/yKifVyGud4c 1637 2025-08-12T14:31:24.000Z 2026-10-22T18:54:04.135Z https://longevityharbor.com/en/watch/yMCe3tk0H8s Session 2 Healthy Aging Series Align Biological Clocks: Leveraging Circadian Rhythms for Sleep https://i.ytimg.com/vi/yMCe3tk0H8s/hqdefault.jpg This 5-part webinar series, presented by Guest Dr. Shilpi Gupta, will include the following talks: Decoding Biological Clocks Leveraging Circadian Rhythms for Optimal Sleep Aligning Your Clock for Weight Loss Hydration Rhythms Utilizing the Circadian Code to address Gut Issues This series delves into the diverse Circadian Rhythms within our bodies, followed by discussions on science-backed techniques to harness our biological clock for enhanced well-being. For this series the speaker will be virtual. You can either attend in-person at the Civic Centre Resource Library, or virtually on Zoom. For more information about Dr. Gupta: curiousandcreativelab.ca Click here to place a hold on her book based on her previous series. Please note that this session is intended for your personal learning purposes and does not provide direct medical advice. Any information learned in this session does not replace information that you receive from your family doctor or healthcare providers. This is a recording of a live virtual program on April 4, 2024. https://www.youtube-nocookie.com/embed/yMCe3tk0H8s 3734 2024-05-02T12:00:54.000Z 2026-10-22T18:54:01.957Z https://longevityharbor.com/de/watch/yMCe3tk0H8s Session 2 Healthy Aging Series Align Biological Clocks: Leveraging Circadian Rhythms for Sleep https://i.ytimg.com/vi/yMCe3tk0H8s/hqdefault.jpg This 5-part webinar series, presented by Guest Dr. Shilpi Gupta, will include the following talks: Decoding Biological Clocks Leveraging Circadian Rhythms for Optimal Sleep Aligning Your Clock for Weight Loss Hydration Rhythms Utilizing the Circadian Code to address Gut Issues This series delves into the diverse Circadian Rhythms within our bodies, followed by discussions on science-backed techniques to harness our biological clock for enhanced well-being. For this series the speaker will be virtual. You can either attend in-person at the Civic Centre Resource Library, or virtually on Zoom. For more information about Dr. Gupta: curiousandcreativelab.ca Click here to place a hold on her book based on her previous series. Please note that this session is intended for your personal learning purposes and does not provide direct medical advice. Any information learned in this session does not replace information that you receive from your family doctor or healthcare providers. This is a recording of a live virtual program on April 4, 2024. https://www.youtube-nocookie.com/embed/yMCe3tk0H8s 3734 2024-05-02T12:00:54.000Z 2026-10-22T18:54:01.957Z https://longevityharbor.com/en/watch/yPK9o3CfXJA This is Growing Old: The Role of Nutrition in Healthy Aging https://i.ytimg.com/vi/yPK9o3CfXJA/hqdefault.jpg Alliance for Aging Research President and CEO Sue Peschin interviews Lindsay Clarke, the Alliance’s Vice President of Health Education and Advocacy, about the importance of good nutrition for healthy aging. Listen and subscribe to This is Growing Old, a podcast from the Alliance for Aging Research: https://anchor.fm/allianceforagingresearch https://www.youtube-nocookie.com/embed/yPK9o3CfXJA 882 2021-06-30T19:58:25.000Z 2026-10-23T01:53:57.200Z https://longevityharbor.com/de/watch/yPK9o3CfXJA This is Growing Old: The Role of Nutrition in Healthy Aging https://i.ytimg.com/vi/yPK9o3CfXJA/hqdefault.jpg Alliance for Aging Research President and CEO Sue Peschin interviews Lindsay Clarke, the Alliance’s Vice President of Health Education and Advocacy, about the importance of good nutrition for healthy aging. Listen and subscribe to This is Growing Old, a podcast from the Alliance for Aging Research: https://anchor.fm/allianceforagingresearch https://www.youtube-nocookie.com/embed/yPK9o3CfXJA 882 2021-06-30T19:58:25.000Z 2026-10-23T01:53:57.200Z https://longevityharbor.com/en/watch/yQUr0s-V8M0 445. Breakthroughs in Anti-Aging: Senolytics and Cellular Health Revealed https://i.ytimg.com/vi/yQUr0s-V8M0/hqdefault.jpg My guest in this cutting edge episode is Greg Kelly from Qualia Senolytic. Greg will be diving into cellular senescence – and together we're unveiling the secrets behind reversing age. Why? Because with the latest studies and emerging research, it’s clear that tackling senescent cells could be a game-changer in the quest to slow down the aging process. These "zombie" cells don’t just age us, they wreak havoc on our health, setting the stage for age related issues. And believe me, I was as curious as anyone about how we could possibly combat these senescent cells until we started peeling back the layers. It turns out, the answer might be senolytics – natural and pharmaceutical compounds showing promise in eliminating these problematic cells. We're talking about quercetin, fisetin, and other potent allies that can pave the way for healthier, longer lives. So, we're here to pass on this crucial information to you – chew on it, see where it fits, and maybe get started on your own journey of age reversal. Connect with Qualia Senolytic: http://neurohacker.com/thyroid Use the code THYROID for 15% off your order Shop ALL of Dr. Amie's Fixxr® Supplements: betterlifedoctor.com (https://dramiehornaman.com/collections/all) LET'S GET YOUR LIFE BACK...Connect with Dr. Amie Hornaman Book a free application call: https://dramiehornaman.com/pages/book-a-call FREE DOWNLOADS… What Are the Optimal Lab Ranges? What Steps Can I Take? (https://dramie.ac-page.com/get-these-labs) Don't know where to start...don't know which labs are useful? And what to do when you get your results? “How To” Guide For Supplements (https://dramie.ac-page.com/how-to-guide-for-supplements) Here’s your Fixxr® supplement timeline and guide. Fix Your Thyroid and Adrenals To Fix Your Life (https://dramie.ac-page.com/lab-and-symptom-checklist) Check your symptoms of hypothyroidism and know OPTIMAL thyroid lab values. Learn why you are being told you’re “NORMAL” by your doctor. Can Supplements Help wi https://www.youtube-nocookie.com/embed/yQUr0s-V8M0 3676 2024-08-16T05:42:08.000Z 2026-10-22T19:21:23.225Z https://longevityharbor.com/de/watch/yQUr0s-V8M0 445. Breakthroughs in Anti-Aging: Senolytics and Cellular Health Revealed https://i.ytimg.com/vi/yQUr0s-V8M0/hqdefault.jpg My guest in this cutting edge episode is Greg Kelly from Qualia Senolytic. Greg will be diving into cellular senescence – and together we're unveiling the secrets behind reversing age. Why? Because with the latest studies and emerging research, it’s clear that tackling senescent cells could be a game-changer in the quest to slow down the aging process. These "zombie" cells don’t just age us, they wreak havoc on our health, setting the stage for age related issues. And believe me, I was as curious as anyone about how we could possibly combat these senescent cells until we started peeling back the layers. It turns out, the answer might be senolytics – natural and pharmaceutical compounds showing promise in eliminating these problematic cells. We're talking about quercetin, fisetin, and other potent allies that can pave the way for healthier, longer lives. So, we're here to pass on this crucial information to you – chew on it, see where it fits, and maybe get started on your own journey of age reversal. Connect with Qualia Senolytic: http://neurohacker.com/thyroid Use the code THYROID for 15% off your order Shop ALL of Dr. Amie's Fixxr® Supplements: betterlifedoctor.com (https://dramiehornaman.com/collections/all) LET'S GET YOUR LIFE BACK...Connect with Dr. Amie Hornaman Book a free application call: https://dramiehornaman.com/pages/book-a-call FREE DOWNLOADS… What Are the Optimal Lab Ranges? What Steps Can I Take? (https://dramie.ac-page.com/get-these-labs) Don't know where to start...don't know which labs are useful? And what to do when you get your results? “How To” Guide For Supplements (https://dramie.ac-page.com/how-to-guide-for-supplements) Here’s your Fixxr® supplement timeline and guide. Fix Your Thyroid and Adrenals To Fix Your Life (https://dramie.ac-page.com/lab-and-symptom-checklist) Check your symptoms of hypothyroidism and know OPTIMAL thyroid lab values. Learn why you are being told you’re “NORMAL” by your doctor. Can Supplements Help wi https://www.youtube-nocookie.com/embed/yQUr0s-V8M0 3676 2024-08-16T05:42:08.000Z 2026-10-22T19:21:23.225Z https://longevityharbor.com/en/watch/yVmnHA4UGZk Video description outlines 12 aging hallmarks and lifestyle factors https://i.ytimg.com/vi/yVmnHA4UGZk/hqdefault.jpg The description says the video explains 12 hallmarks of aging, from cellular senescence to telomeres, and discusses diet, exercise and sleep as ways to influence cellular pathways. It claims habits affect biological age but does not report study results. https://www.youtube-nocookie.com/embed/yVmnHA4UGZk 172 2025-12-20T13:06:28.000Z 2026-10-23T03:14:54.861Z https://longevityharbor.com/de/watch/yVmnHA4UGZk Videobeschreibung skizziert 12 Hallmarks des Alterns und Lebensstilfaktoren https://i.ytimg.com/vi/yVmnHA4UGZk/hqdefault.jpg Laut Beschreibung erklärt das Video 12 Hallmarks des Alterns, von zellulärer Seneszenz bis Telomeren, und behandelt Ernährung, Bewegung und Schlaf als Wege, zelluläre Pfade zu beeinflussen. Es behauptet, Gewohnheiten beeinflussten das biologische Alter, nennt aber keine Studienergebnisse. https://www.youtube-nocookie.com/embed/yVmnHA4UGZk 172 2025-12-20T13:06:28.000Z 2026-10-23T03:14:54.861Z https://longevityharbor.com/en/watch/yWmAEaqQ5To Age Backwards? The Truth About NMN and Longevity https://i.ytimg.com/vi/yWmAEaqQ5To/hqdefault.jpg NAD+ boosters, such as NAD+ IV and NMN-NR supplements, are gaining attention in the longevity space, with Hollywood stars turning to them to maintain youthfulness and extend their lifespan. In this video, we dive deep into the science of NAD+ and its fascinating connection to longevity. https://decodeage.com/products/nmn500?utm_source=Youtube&utm_medium=NMN Topics we’ll cover: ✅ Why do we age? ✅ Is aging inevitable, or can it be reversed? ✅ How the discovery of sirtuin genes is revolutionizing the field of longevity. ✅ The link between sirtuins, NAD+, and longevity explained. ✅ Comparing ways to boost NAD+ levels: NAD+ IV, NMN, and NR supplements. ✅ The FDA's ban on NMN: What it means and why it happened. ✅ The benefits of NMN supplementation for health and longevity. Stay connected to learn more about longevity and healthy aging. Like, share, and subscribe to our channel. Social Media and Website: Instagram: instagram.com/decodeage Facebook: facebook.com/DecodeAge Twitter: twitter.com/DecodeAge Pinterest: in.pinterest.com/decodeage LinkedIn: linkedin.com/company/decogeage Website: https://decodeage.com/ Timestamps: 0:17: Why is NAD so popular? 1:24: Why can't humans live longer? 1:50: Lifespan vs Healthspan 2:26: Why does our health get worse with age? 2:53: Why does age increase the risk of dementia? 3:41: Other examples of diseases caused by cellular damage 4:05: Is aging an inevitable process? 5:32: The longevity breakthrough: Sirtuin genes 6:35: Sirtuins, NAD and Longevity: Link explained 7:31: How to boost NAD+ levels? 8:19: NAD+ supplements: NMN vs NR 9:21: Is NMN safe to take? 10:07: Why did the FDA ban NMN? 10:43: What are the benefits of NMN? 12:23: Decode Age: India's Pioneers in Longevity #NMN #NAD+ #Healthyageing https://www.youtube-nocookie.com/embed/yWmAEaqQ5To 788 2024-12-26T16:24:26.000Z 2026-10-22T20:11:48.430Z https://longevityharbor.com/de/watch/yWmAEaqQ5To Age Backwards? The Truth About NMN and Longevity https://i.ytimg.com/vi/yWmAEaqQ5To/hqdefault.jpg NAD+ boosters, such as NAD+ IV and NMN-NR supplements, are gaining attention in the longevity space, with Hollywood stars turning to them to maintain youthfulness and extend their lifespan. In this video, we dive deep into the science of NAD+ and its fascinating connection to longevity. https://decodeage.com/products/nmn500?utm_source=Youtube&utm_medium=NMN Topics we’ll cover: ✅ Why do we age? ✅ Is aging inevitable, or can it be reversed? ✅ How the discovery of sirtuin genes is revolutionizing the field of longevity. ✅ The link between sirtuins, NAD+, and longevity explained. ✅ Comparing ways to boost NAD+ levels: NAD+ IV, NMN, and NR supplements. ✅ The FDA's ban on NMN: What it means and why it happened. ✅ The benefits of NMN supplementation for health and longevity. Stay connected to learn more about longevity and healthy aging. Like, share, and subscribe to our channel. Social Media and Website: Instagram: instagram.com/decodeage Facebook: facebook.com/DecodeAge Twitter: twitter.com/DecodeAge Pinterest: in.pinterest.com/decodeage LinkedIn: linkedin.com/company/decogeage Website: https://decodeage.com/ Timestamps: 0:17: Why is NAD so popular? 1:24: Why can't humans live longer? 1:50: Lifespan vs Healthspan 2:26: Why does our health get worse with age? 2:53: Why does age increase the risk of dementia? 3:41: Other examples of diseases caused by cellular damage 4:05: Is aging an inevitable process? 5:32: The longevity breakthrough: Sirtuin genes 6:35: Sirtuins, NAD and Longevity: Link explained 7:31: How to boost NAD+ levels? 8:19: NAD+ supplements: NMN vs NR 9:21: Is NMN safe to take? 10:07: Why did the FDA ban NMN? 10:43: What are the benefits of NMN? 12:23: Decode Age: India's Pioneers in Longevity #NMN #NAD+ #Healthyageing https://www.youtube-nocookie.com/embed/yWmAEaqQ5To 788 2024-12-26T16:24:26.000Z 2026-10-22T20:11:48.430Z https://longevityharbor.com/en/watch/yWolvlYQkRg NMN & Trans-Resveratrol – The Ultimate Anti-Aging Breakthrough https://i.ytimg.com/vi/yWolvlYQkRg/hqdefault.jpg 🔥 Can NMN & Trans-Resveratrol Reverse Aging? Scientists are uncovering the powerful anti-aging effects of these two longevity compounds, and the results are mind-blowing! 🧬✨ In this video, we break down the latest groundbreaking studies on NMN (Nicotinamide Mononucleotide) and Trans-Resveratrol—and how they work together to boost energy, improve brain function, and support cellular health. But does the science hold up? Let’s find out! 🎥 What You’ll Learn in This Video: ✅ What is NMN & why is it linked to longevity & energy? ✅ The shocking Harvard studies on NAD+ & aging 👀 ✅ How NMN & Trans-Resveratrol work together for maximum impact! ✅ The real benefits people are seeing from these supplements ✅ Should YOU start taking NMN & Resveratrol? 🤔 🔗 Related Content & Supplements: 🌱 Check out premium NMN & Trans-Resveratrol supplements here: https://www.vegishake.co.uk 🎯 Read more on NMN & longevity here: [Insert blog link] 🧠 Watch our other longevity videos: [Insert playlist link] 📢 💥 Limited-Time Offer! Use code FIRSTTIME for 10% OFF your first order at Vegishake! --- 🔥 Call to Action – Engage with Us! 💬 What are your thoughts on NMN & Trans-Resveratrol? Have you tried them? Comment below and let’s discuss! 👍 Like this video? Smash that LIKE button! 🔔 Subscribe & Turn on Notifications so you never miss an update on longevity science! --- 🔍 Frequently Asked Questions (FAQs): 💡 Q: What does NMN do for your body? A: NMN is a precursor to NAD+, a vital coenzyme that fuels cellular energy, metabolism, and DNA repair. 💡 Q: What is Trans-Resveratrol? A: A powerful polyphenol found in grapes & berries, known for its antioxidant & anti-inflammatory properties, and linked to longevity support. 💡 Q: Is it safe to take NMN daily? A: Most research suggests NMN is safe & well-tolerated at standard doses, but always consult a healthcare provider before starting a new supplement. 💡 Q: How long does it take to see results? A: Many users report feeling increased energy and mental clarity within a few https://www.youtube-nocookie.com/embed/yWolvlYQkRg 143 2025-03-16T16:55:00.000Z 2026-10-22T19:04:42.040Z https://longevityharbor.com/de/watch/yWolvlYQkRg NMN & Trans-Resveratrol – The Ultimate Anti-Aging Breakthrough https://i.ytimg.com/vi/yWolvlYQkRg/hqdefault.jpg 🔥 Can NMN & Trans-Resveratrol Reverse Aging? Scientists are uncovering the powerful anti-aging effects of these two longevity compounds, and the results are mind-blowing! 🧬✨ In this video, we break down the latest groundbreaking studies on NMN (Nicotinamide Mononucleotide) and Trans-Resveratrol—and how they work together to boost energy, improve brain function, and support cellular health. But does the science hold up? Let’s find out! 🎥 What You’ll Learn in This Video: ✅ What is NMN & why is it linked to longevity & energy? ✅ The shocking Harvard studies on NAD+ & aging 👀 ✅ How NMN & Trans-Resveratrol work together for maximum impact! ✅ The real benefits people are seeing from these supplements ✅ Should YOU start taking NMN & Resveratrol? 🤔 🔗 Related Content & Supplements: 🌱 Check out premium NMN & Trans-Resveratrol supplements here: https://www.vegishake.co.uk 🎯 Read more on NMN & longevity here: [Insert blog link] 🧠 Watch our other longevity videos: [Insert playlist link] 📢 💥 Limited-Time Offer! Use code FIRSTTIME for 10% OFF your first order at Vegishake! --- 🔥 Call to Action – Engage with Us! 💬 What are your thoughts on NMN & Trans-Resveratrol? Have you tried them? Comment below and let’s discuss! 👍 Like this video? Smash that LIKE button! 🔔 Subscribe & Turn on Notifications so you never miss an update on longevity science! --- 🔍 Frequently Asked Questions (FAQs): 💡 Q: What does NMN do for your body? A: NMN is a precursor to NAD+, a vital coenzyme that fuels cellular energy, metabolism, and DNA repair. 💡 Q: What is Trans-Resveratrol? A: A powerful polyphenol found in grapes & berries, known for its antioxidant & anti-inflammatory properties, and linked to longevity support. 💡 Q: Is it safe to take NMN daily? A: Most research suggests NMN is safe & well-tolerated at standard doses, but always consult a healthcare provider before starting a new supplement. 💡 Q: How long does it take to see results? A: Many users report feeling increased energy and mental clarity within a few https://www.youtube-nocookie.com/embed/yWolvlYQkRg 143 2025-03-16T16:55:00.000Z 2026-10-22T19:04:42.040Z https://longevityharbor.com/en/watch/yqjuWdWtJF8 Ageing, Cellular Senescence and Senolytics: The Path to Translation | Prof James Kirkland https://i.ytimg.com/vi/yqjuWdWtJF8/hqdefault.jpg In this #webinar, Prof James Kirkland, Director of the Robert and Arlene Kogod Centre on Ageing at Mayo Clinic, talked about about cellular senescence in ageing, therapeutic potential of senolytics, current clinical trials and the path to translation. Register for upcoming #HealthyLongevity #webinar​​ sessions at https://nus-sg.zoom.us/webinar/register/3016397215018/WN__sypkX6ZSomc7cGAkK3LbA #NUSMedicine​​​​​ #webinarseries​​​​​ References: - Closing video source: https://www.youtube.com/watch?v=aFGkthyNjLk --- Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material. https://www.youtube-nocookie.com/embed/yqjuWdWtJF8 3933 2021-12-10T02:46:31.000Z 2026-10-23T02:56:02.647Z https://longevityharbor.com/de/watch/yqjuWdWtJF8 Ageing, Cellular Senescence and Senolytics: The Path to Translation | Prof James Kirkland https://i.ytimg.com/vi/yqjuWdWtJF8/hqdefault.jpg In this #webinar, Prof James Kirkland, Director of the Robert and Arlene Kogod Centre on Ageing at Mayo Clinic, talked about about cellular senescence in ageing, therapeutic potential of senolytics, current clinical trials and the path to translation. Register for upcoming #HealthyLongevity #webinar​​ sessions at https://nus-sg.zoom.us/webinar/register/3016397215018/WN__sypkX6ZSomc7cGAkK3LbA #NUSMedicine​​​​​ #webinarseries​​​​​ References: - Closing video source: https://www.youtube.com/watch?v=aFGkthyNjLk --- Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material. https://www.youtube-nocookie.com/embed/yqjuWdWtJF8 3933 2021-12-10T02:46:31.000Z 2026-10-23T02:56:02.647Z https://longevityharbor.com/en/watch/yrs0MXxPv5g Explainer describes epigenetic clocks that estimate biological age from DNA changes https://i.ytimg.com/vi/yrs0MXxPv5g/hqdefault.jpg According to the description, the video explains the epigenetic clock, a technology that estimates biological age from chemical changes in DNA, and asks how it could reshape healthspan and medicine as AI, regenerative medicine and cell reprogramming advance. https://www.youtube-nocookie.com/embed/yrs0MXxPv5g 370 2026-02-22T15:01:38.000Z 2026-10-23T02:25:56.516Z https://longevityharbor.com/de/watch/yrs0MXxPv5g Erklärvideo beschreibt epigenetische Uhren, die biologisches Alter aus DNA-Veränderungen schätzen https://i.ytimg.com/vi/yrs0MXxPv5g/hqdefault.jpg Laut Beschreibung erklärt das Video die epigenetische Uhr, eine Technologie, die biologisches Alter aus chemischen Veränderungen der DNA schätzt, und fragt, wie sie Healthspan und Medizin verändern könnte, während KI, regenerative Medizin und Zellreprogrammierung voranschreiten. https://www.youtube-nocookie.com/embed/yrs0MXxPv5g 370 2026-02-22T15:01:38.000Z 2026-10-23T02:25:56.516Z https://longevityharbor.com/en/watch/yu3BBZAiVvY Video Description: 15 Everyday Foods Claimed to Support Healthy Aging After 50 https://i.ytimg.com/vi/yu3BBZAiVvY/hqdefault.jpg This video description lists 15 everyday foods said to contain nutrients that may support skin, cells and brain as people age. It stresses that no single food reverses aging and that consistent nutrition, movement and sleep matter. No studies, numbers or outcomes are reported. https://www.youtube-nocookie.com/embed/yu3BBZAiVvY 579 2026-10-22T19:19:37.000Z 2026-10-22T19:52:45.867Z https://longevityharbor.com/de/watch/yu3BBZAiVvY Videobeschreibung: 15 Alltagslebensmittel, die gesundes Altern nach 50 unterstützen sollen https://i.ytimg.com/vi/yu3BBZAiVvY/hqdefault.jpg Diese Videobeschreibung nennt 15 Alltagslebensmittel, die Nährstoffe enthalten sollen, die Haut, Zellen und Gehirn beim Altern unterstützen könnten. Sie betont, dass kein einzelnes Lebensmittel das Altern umkehrt und dass beständige Ernährung, Bewegung und Schlaf zählen. Studien, Zahlen oder Ergebnisse werden nicht berichtet. https://www.youtube-nocookie.com/embed/yu3BBZAiVvY 579 2026-10-22T19:19:37.000Z 2026-10-22T19:52:45.867Z https://longevityharbor.com/en/watch/yuKrtQZWoQQ Why We Study Senescence https://i.ytimg.com/vi/yuKrtQZWoQQ/hqdefault.jpg So, i am currently working on designing our lab website and it was suggested to do a video just describing senescence as opposed to my previous videos where i briefly mention it before jumping into the depths of a recent publication. So, here we are with a video all about senescence. References; Baker, D., Wijshake, T., Tchkonia, T. et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 479, 232–236 (2011). [https://doi.org/10.1038/nature10600](https://doi.org/10.1038/nature10600) Short-term gain, long-term pain: the senescence life cycle and cancer doi:10.1101/gad.320937.118 *Genes & Dev.* 2019. 33: 127-143 Cellular Senescence: Defining a Path Forward [https://doi.org/10.1016/j.cell.2019.10.005](https://doi.org/10.1016/j.cell.2019.10.005) https://www.youtube-nocookie.com/embed/yuKrtQZWoQQ 646 2020-06-06T16:03:12.000Z 2026-10-23T02:56:02.525Z https://longevityharbor.com/de/watch/yuKrtQZWoQQ Why We Study Senescence https://i.ytimg.com/vi/yuKrtQZWoQQ/hqdefault.jpg So, i am currently working on designing our lab website and it was suggested to do a video just describing senescence as opposed to my previous videos where i briefly mention it before jumping into the depths of a recent publication. So, here we are with a video all about senescence. References; Baker, D., Wijshake, T., Tchkonia, T. et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 479, 232–236 (2011). [https://doi.org/10.1038/nature10600](https://doi.org/10.1038/nature10600) Short-term gain, long-term pain: the senescence life cycle and cancer doi:10.1101/gad.320937.118 *Genes & Dev.* 2019. 33: 127-143 Cellular Senescence: Defining a Path Forward [https://doi.org/10.1016/j.cell.2019.10.005](https://doi.org/10.1016/j.cell.2019.10.005) https://www.youtube-nocookie.com/embed/yuKrtQZWoQQ 646 2020-06-06T16:03:12.000Z 2026-10-23T02:56:02.525Z https://longevityharbor.com/en/watch/yvV_9zb309o Does Caloric Restriction Increase Lifespan? | Two RCTs and future directions https://i.ytimg.com/vi/yvV_9zb309o/hqdefault.jpg Vinay Prasad, MD MPH; Physician & Professor Hematologist/ Oncologist Professor of Epidemiology, Biostatistics and Medicine Author of 500+ Peer Reviewed papers, 2 Books, 2 Podcasts, 100+ op-eds. If you want to contact me, do it here: http://www.vinayakkprasad.com/contact Instagram: https://www.instagram.com/vprasadmdmph/ Google Scholar: https://scholar.google.com/citations?user=ym4rwk0AAAAJ&hl=en Substack: https://vinayprasadmdmph.substack.com/ Podcast: https://podcasts.apple.com/us/podcast/plenary-session/id1429998903 Personal Website: www.vinayakkprasad.com Laboratory Website: www.vkprasadlab.com Podcast Website: www.plenarysessionpodcast.com Academic Publications: http://www.vinayakkprasad.com/papers Follow me on: Twitter @vprasadmdmph https://www.youtube-nocookie.com/embed/yvV_9zb309o 1344 2026-06-04T20:13:10.000Z 2026-10-22T17:43:38.417Z https://longevityharbor.com/de/watch/yvV_9zb309o Does Caloric Restriction Increase Lifespan? | Two RCTs and future directions https://i.ytimg.com/vi/yvV_9zb309o/hqdefault.jpg Vinay Prasad, MD MPH; Physician & Professor Hematologist/ Oncologist Professor of Epidemiology, Biostatistics and Medicine Author of 500+ Peer Reviewed papers, 2 Books, 2 Podcasts, 100+ op-eds. If you want to contact me, do it here: http://www.vinayakkprasad.com/contact Instagram: https://www.instagram.com/vprasadmdmph/ Google Scholar: https://scholar.google.com/citations?user=ym4rwk0AAAAJ&hl=en Substack: https://vinayprasadmdmph.substack.com/ Podcast: https://podcasts.apple.com/us/podcast/plenary-session/id1429998903 Personal Website: www.vinayakkprasad.com Laboratory Website: www.vkprasadlab.com Podcast Website: www.plenarysessionpodcast.com Academic Publications: http://www.vinayakkprasad.com/papers Follow me on: Twitter @vprasadmdmph https://www.youtube-nocookie.com/embed/yvV_9zb309o 1344 2026-06-04T20:13:10.000Z 2026-10-22T17:43:38.417Z https://longevityharbor.com/en/watch/ywXQ-u1X6tY Creator credits David Sinclair's work as early longevity inspiration https://i.ytimg.com/vi/ywXQ-u1X6tY/hqdefault.jpg The creator says David Sinclair's work sparked early interest in longevity and aging biology, including NAD and NMN, and stresses following evidence rather than trends. https://www.youtube-nocookie.com/embed/ywXQ-u1X6tY 90 2026-10-05T19:29:42.000Z 2026-10-22T21:19:05.866Z https://longevityharbor.com/de/watch/ywXQ-u1X6tY Ersteller nennt David Sinclairs Arbeit als frühe Inspiration für Langlebigkeit https://i.ytimg.com/vi/ywXQ-u1X6tY/hqdefault.jpg Der Ersteller sagt, David Sinclairs Arbeit habe früh Interesse an Langlebigkeit und Alternsbiologie geweckt, auch an NAD und NMN, und betont, der Evidenz statt Trends zu folgen. https://www.youtube-nocookie.com/embed/ywXQ-u1X6tY 90 2026-10-05T19:29:42.000Z 2026-10-22T21:19:05.866Z https://longevityharbor.com/en/watch/yzmIe76ShRU Critical Findings From 15 Key NMN Human Studies https://i.ytimg.com/vi/yzmIe76ShRU/hqdefault.jpg 👇Unbeatable SAVINGS on NMN Must-Haves!👇 🚨GenuinePurity NMN (Use code HEALTHFRIDAY15 and get 15% OFF) https://hlth.news/GenP-NMN-LIMITED/ 🚨ProHealth NMN (Subscribe to ProHealth's newsletter and get 30% OFF) https://hlth.news/ProHealth-NMN-DEAL/ 🚨partiQlar NMN (Use code healthnews10 and get 10% OFF) https://hlth.news/Grab-PartiQlar-NMN/ NMN, or Nicotinamide Mononucleotide, received significant attention as a potential anti-aging product. NMN is a precursor to NAD+, a coenzyme vital for cellular energy production and metabolism. Longevity enthusiasts claim that NMN can extend lifespan, enhance metabolic functions, and reverse aspects of aging. However, with the popularity comes a need for critical NMN evaluation. NMN human trials often have limitations like small sample sizes and short durations, making it challenging to draw definitive conclusions about NMN's efficacy and safety. This video is an in-depth analysis of 15 significant human studies on Nicotinamide Mononucleotide (NMN). We break down the findings of NMN human studies, focusing on NMN's impact on various health markers, including metabolic health, muscle insulin sensitivity, physical performance, and overall longevity. However, further research is needed to fully explore NMN's efficacy and safety across broader and more diverse populations. #nmn #humanstudies #nmnhumanstudies #nmnresearch #longevity #healthnews 🔔 Subscribe to our YouTube channel @HealthnewsOfficial to always stay in the loop! 🔔 🎬Check out our other videos🎬 How to Replace NMN: Top 4 NMN Alternatives ➡️ https://youtu.be/v5XsgtLAOw4 Best NMN Products in 2024 ➡️ https://youtu.be/r30GbD_cAIY What Science Says About RED LIGHT THERAPY ➡️ https://youtu.be/IarHcgfO4nc What Longevity Experts Take for Longevity? ➡️ https://youtu.be/eLYl76EcoQk 📚 Sources and material 📚 https://pubmed.ncbi.nlm.nih.gov/33888596/ https://pubmed.ncbi.nlm.nih.gov/34238308/ https://pubmed.ncbi.nlm.nih.gov/34238308/ https://pubmed.ncbi.nlm.nih.gov/35215405/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC90 https://www.youtube-nocookie.com/embed/yzmIe76ShRU 597 2024-09-08T14:00:53.000Z 2026-10-22T20:11:48.179Z https://longevityharbor.com/de/watch/yzmIe76ShRU Critical Findings From 15 Key NMN Human Studies https://i.ytimg.com/vi/yzmIe76ShRU/hqdefault.jpg 👇Unbeatable SAVINGS on NMN Must-Haves!👇 🚨GenuinePurity NMN (Use code HEALTHFRIDAY15 and get 15% OFF) https://hlth.news/GenP-NMN-LIMITED/ 🚨ProHealth NMN (Subscribe to ProHealth's newsletter and get 30% OFF) https://hlth.news/ProHealth-NMN-DEAL/ 🚨partiQlar NMN (Use code healthnews10 and get 10% OFF) https://hlth.news/Grab-PartiQlar-NMN/ NMN, or Nicotinamide Mononucleotide, received significant attention as a potential anti-aging product. NMN is a precursor to NAD+, a coenzyme vital for cellular energy production and metabolism. Longevity enthusiasts claim that NMN can extend lifespan, enhance metabolic functions, and reverse aspects of aging. However, with the popularity comes a need for critical NMN evaluation. NMN human trials often have limitations like small sample sizes and short durations, making it challenging to draw definitive conclusions about NMN's efficacy and safety. This video is an in-depth analysis of 15 significant human studies on Nicotinamide Mononucleotide (NMN). We break down the findings of NMN human studies, focusing on NMN's impact on various health markers, including metabolic health, muscle insulin sensitivity, physical performance, and overall longevity. However, further research is needed to fully explore NMN's efficacy and safety across broader and more diverse populations. #nmn #humanstudies #nmnhumanstudies #nmnresearch #longevity #healthnews 🔔 Subscribe to our YouTube channel @HealthnewsOfficial to always stay in the loop! 🔔 🎬Check out our other videos🎬 How to Replace NMN: Top 4 NMN Alternatives ➡️ https://youtu.be/v5XsgtLAOw4 Best NMN Products in 2024 ➡️ https://youtu.be/r30GbD_cAIY What Science Says About RED LIGHT THERAPY ➡️ https://youtu.be/IarHcgfO4nc What Longevity Experts Take for Longevity? ➡️ https://youtu.be/eLYl76EcoQk 📚 Sources and material 📚 https://pubmed.ncbi.nlm.nih.gov/33888596/ https://pubmed.ncbi.nlm.nih.gov/34238308/ https://pubmed.ncbi.nlm.nih.gov/34238308/ https://pubmed.ncbi.nlm.nih.gov/35215405/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC90 https://www.youtube-nocookie.com/embed/yzmIe76ShRU 597 2024-09-08T14:00:53.000Z 2026-10-22T20:11:48.179Z https://longevityharbor.com/en/watch/z3-j0Gasazc Surgeon's video description: creatine after 50 for muscle, strength and aging https://i.ytimg.com/vi/z3-j0Gasazc/hqdefault.jpg The description says creatine monohydrate may help healthy adults who resistance train preserve strength and muscle with age, but it cannot replace training, protein or medical care. https://www.youtube-nocookie.com/embed/z3-j0Gasazc 558 2026-10-07T20:34:09.000Z 2026-10-22T21:11:38.909Z https://longevityharbor.com/de/watch/z3-j0Gasazc Chirurgen-Videobeschreibung: Kreatin ab 50 für Muskeln, Kraft und Altern https://i.ytimg.com/vi/z3-j0Gasazc/hqdefault.jpg Laut Beschreibung kann Kreatinmonohydrat gesunden Erwachsenen, die Krafttraining machen, helfen, Kraft und Muskeln im Alter zu erhalten; Training, Protein und medizinische Versorgung ersetzt es aber nicht. https://www.youtube-nocookie.com/embed/z3-j0Gasazc 558 2026-10-07T20:34:09.000Z 2026-10-22T21:11:38.909Z https://longevityharbor.com/en/watch/zKdzc943joA Podcast description: sleep needs, circadian shifts and sleep-hygiene tips after 50 https://i.ytimg.com/vi/zKdzc943joA/hqdefault.jpg The description says older adults still need 7 to 9 hours of sleep, that aging shifts the internal clock earlier, and that the hosts offer sleep-hygiene practices; these are creator claims, not reviewed findings. https://www.youtube-nocookie.com/embed/zKdzc943joA 1513 2026-05-18T22:23:28.000Z 2026-10-23T00:38:34.403Z https://longevityharbor.com/de/watch/zKdzc943joA Podcast-Beschreibung: Schlafbedarf, circadiane Verschiebung und Schlafhygiene-Tipps ab 50 https://i.ytimg.com/vi/zKdzc943joA/hqdefault.jpg Laut Beschreibung brauchen ältere Erwachsene weiterhin 7 bis 9 Stunden Schlaf, das Altern verschiebt die innere Uhr nach früher, und die Gastgeber bieten Schlafhygiene-Praktiken an; dies sind Aussagen der Macher, keine geprüften Ergebnisse. https://www.youtube-nocookie.com/embed/zKdzc943joA 1513 2026-05-18T22:23:28.000Z 2026-10-23T00:38:34.403Z https://longevityharbor.com/en/watch/zKv7rtQG3yw AVEA NMN: NAD+ – Das Schlüsselmolekül für Langlebigkeit (verzögert das Altern) https://i.ytimg.com/vi/zKv7rtQG3yw/hqdefault.jpg 🎁 Spare jetzt 15 % auf alle Produkte von AVEA! Nutze einfach meinen exklusiven Rabatt-Code: MARVINSEIDEL 👉 https://avea-life.com/de/products/nmn?aff=marvinseidel 💊 Ich nehme täglich 1 Kapsel NMN – für mehr Energie auf Zellebene ✔️ Füllt dein NAD⁺ auf – ein essentielles Coenzym, das mit dem Alter abnimmt ✔️ Doppelt getestet in der Schweiz – 99 % Reinheit ✔️ 90-Tage-Geld-zurück-Garantie – völlig risikofrei testen Inhalt: Intro: 0:00 Meine persönlichen Erfahrungen: 0:36 Was ist NMN?: 2:38 Die Rolle von NAD+: Der Schlüssel zu jugendlicher Vitalität: 2:58 Das Problem mit NAD+: 3:37 Warum ist NMN so effektiv?: 4:27 Die Vorteile von NMN – Detaillierte Einblicke 1. Mehr Energie und Vitalität: 4:45 2. Verlangsamung des Alterungsprozesses: 6:42 3. Verbesserte Fitness und Regeneration: 8:06 4. Schutz vor Alterskrankheiten – Langfristige Gesundheit sichern: 9:02 4.1 Gehirngesundheit – Schutz vor Alzheimer und Demenz: 9:39 4.3 Diabetes und Stoffwechsel – Regulierung des Blutzuckers: 10:48 4.4 Gelenk- und Knochengesundheit – Beweglich bleiben im Alter: 11:52 5. Kritische Punkte zum Thema NMN: 12:57 5. Warum genau NMN von Avea?: 14:41 Studien: DNA Reparatur: https://pubmed.ncbi.nlm.nih.gov/28336669/ https://pubmed.ncbi.nlm.nih.gov/30930169/ https://www.sciencedirect.com/science/article/pii/S1756464623005856#:~:text=We%20found%20that%20NMN%20significantly,51%20%25)%20in%20atherosclerotic%20lesions. https://pubmed.ncbi.nlm.nih.gov/38333051/ Stoffwechsel: https://pubmed.ncbi.nlm.nih.gov/36740954/ https://pubmed.ncbi.nlm.nih.gov/37344088/ https://www.toukastress.jp/webj/article/2022/GS22-16.pdf https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-024-05614-9#:~:text=Neuroprotection%3A%20There%20is%20evidence%20to,NAD%20%2B%20levels%20%5B77%5D. Altern und Longevity: https://pubmed.ncbi.nlm.nih.gov/34912838/ https://pubmed.ncbi.nlm.nih.gov/28068222/ https://www.nature.com/articles/s41467-019-13172-8#citeas https://www.nature.com/articles/nrm.2016.93 https://pmc.ncbi.nlm.nih.gov/articles/PMC5668137/ ht https://www.youtube-nocookie.com/embed/zKv7rtQG3yw 1067 2025-02-04T17:01:12.000Z 2026-10-22T17:43:42.533Z https://longevityharbor.com/de/watch/zKv7rtQG3yw AVEA NMN: NAD+ – Das Schlüsselmolekül für Langlebigkeit (verzögert das Altern) https://i.ytimg.com/vi/zKv7rtQG3yw/hqdefault.jpg 🎁 Spare jetzt 15 % auf alle Produkte von AVEA! Nutze einfach meinen exklusiven Rabatt-Code: MARVINSEIDEL 👉 https://avea-life.com/de/products/nmn?aff=marvinseidel 💊 Ich nehme täglich 1 Kapsel NMN – für mehr Energie auf Zellebene ✔️ Füllt dein NAD⁺ auf – ein essentielles Coenzym, das mit dem Alter abnimmt ✔️ Doppelt getestet in der Schweiz – 99 % Reinheit ✔️ 90-Tage-Geld-zurück-Garantie – völlig risikofrei testen Inhalt: Intro: 0:00 Meine persönlichen Erfahrungen: 0:36 Was ist NMN?: 2:38 Die Rolle von NAD+: Der Schlüssel zu jugendlicher Vitalität: 2:58 Das Problem mit NAD+: 3:37 Warum ist NMN so effektiv?: 4:27 Die Vorteile von NMN – Detaillierte Einblicke 1. Mehr Energie und Vitalität: 4:45 2. Verlangsamung des Alterungsprozesses: 6:42 3. Verbesserte Fitness und Regeneration: 8:06 4. Schutz vor Alterskrankheiten – Langfristige Gesundheit sichern: 9:02 4.1 Gehirngesundheit – Schutz vor Alzheimer und Demenz: 9:39 4.3 Diabetes und Stoffwechsel – Regulierung des Blutzuckers: 10:48 4.4 Gelenk- und Knochengesundheit – Beweglich bleiben im Alter: 11:52 5. Kritische Punkte zum Thema NMN: 12:57 5. Warum genau NMN von Avea?: 14:41 Studien: DNA Reparatur: https://pubmed.ncbi.nlm.nih.gov/28336669/ https://pubmed.ncbi.nlm.nih.gov/30930169/ https://www.sciencedirect.com/science/article/pii/S1756464623005856#:~:text=We%20found%20that%20NMN%20significantly,51%20%25)%20in%20atherosclerotic%20lesions. https://pubmed.ncbi.nlm.nih.gov/38333051/ Stoffwechsel: https://pubmed.ncbi.nlm.nih.gov/36740954/ https://pubmed.ncbi.nlm.nih.gov/37344088/ https://www.toukastress.jp/webj/article/2022/GS22-16.pdf https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-024-05614-9#:~:text=Neuroprotection%3A%20There%20is%20evidence%20to,NAD%20%2B%20levels%20%5B77%5D. Altern und Longevity: https://pubmed.ncbi.nlm.nih.gov/34912838/ https://pubmed.ncbi.nlm.nih.gov/28068222/ https://www.nature.com/articles/s41467-019-13172-8#citeas https://www.nature.com/articles/nrm.2016.93 https://pmc.ncbi.nlm.nih.gov/articles/PMC5668137/ ht https://www.youtube-nocookie.com/embed/zKv7rtQG3yw 1067 2025-02-04T17:01:12.000Z 2026-10-22T17:43:42.533Z https://longevityharbor.com/en/watch/zL3XujbI06s Is rapamycin worth taking? https://i.ytimg.com/vi/zL3XujbI06s/hqdefault.jpg Here’s the truth… #DaveAsprey #biohacking #biohacker #biohacked #longevity #antiaging #aging #rapamycin #health #wellness #wellbeing https://www.youtube-nocookie.com/embed/zL3XujbI06s 91 2025-03-24T21:30:09.000Z 2026-10-22T19:54:21.213Z https://longevityharbor.com/de/watch/zL3XujbI06s Is rapamycin worth taking? https://i.ytimg.com/vi/zL3XujbI06s/hqdefault.jpg Here’s the truth… #DaveAsprey #biohacking #biohacker #biohacked #longevity #antiaging #aging #rapamycin #health #wellness #wellbeing https://www.youtube-nocookie.com/embed/zL3XujbI06s 91 2025-03-24T21:30:09.000Z 2026-10-22T19:54:21.213Z https://longevityharbor.com/en/watch/zNQLkhydojM NAD vs NMN? The powerful anti-aging tools each have their benefits https://i.ytimg.com/vi/zNQLkhydojM/hqdefault.jpg NAD vs NMN? The powerful anti-aging tools each have their benefits. #nmn #newyearnewme #antiaging #tiktokshopjumpstartsale #over40 https://www.youtube-nocookie.com/embed/zNQLkhydojM 117 2026-09-23T21:08:11.000Z 2026-10-22T17:43:42.538Z https://longevityharbor.com/de/watch/zNQLkhydojM NAD vs NMN? The powerful anti-aging tools each have their benefits https://i.ytimg.com/vi/zNQLkhydojM/hqdefault.jpg NAD vs NMN? The powerful anti-aging tools each have their benefits. #nmn #newyearnewme #antiaging #tiktokshopjumpstartsale #over40 https://www.youtube-nocookie.com/embed/zNQLkhydojM 117 2026-09-23T21:08:11.000Z 2026-10-22T17:43:42.538Z https://longevityharbor.com/en/watch/zVdjdocl3xI Hallmarks of aging – time for a paradigm shift? https://i.ytimg.com/vi/zVdjdocl3xI/hqdefault.jpg If you’re like me, then possibly your first introduction to the field of biogerontology is the 2013 review articles “The hallmarks of aging” by Lopez-Otin et al. This most cited review in the field of aging defines common denominators of aging in different organisms into 9 different hallmarks and is a pretty common reference point for the field. I’ve always liked the hallmarks as an introduction to the field, so much so that I described the hallmarks in some of my earliest videos. Speaking of my earliest videos, given that it’s almost my 2-year birthday on YouTube, I’d thought I’d revisit the hallmarks of aging given that there has been some recent criticism on them suggesting that maybe we should start to look beyond them. So in this video, I’ll first explain why models and paradigms are useful and then show you the different models used to explain aging (as the hallmarks is not the only model), will then look at the limitations of the hallmarks as discussed in this recent critique paper and lastly look at their solution and see if it is time for a paradigm shift. And just to let you know, I have also made this video in tandem with @LongevityScienceNews show whose video you can check out here; https://www.youtube.com/watch?v=DiufT9dvSaI TIMESTAMPS Intro - 00:00 Scientific Paradigms (Thomas Kuhn) - 01:10 Hallmarks of aging - 03:00 Hallmarks of cancer - 06:20 Issues with the hallmarks - 08:20 How to improve the hallmarks - 09:50 My thoughts - 11:00 References: The Hallmarks of Aging - https://doi.org/10.1016/j.cell.2013.05.039 Gems, D.; de Magalhães, J.P. The Hoverfly and the Wasp: A Critique of the Hallmarks of Aging as a Paradigm. Preprints 2021, 2021050310 (doi: 10.20944/preprints202105.0310.v1). The Hallmarks of Cancer - https://doi.org/10.1016/S0092-8674(00)81683-9 Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com https://www.youtube-nocookie.com/embed/zVdjdocl3xI 786 2021-06-11T15:00:28.000Z 2026-10-22T17:43:40.166Z https://longevityharbor.com/de/watch/zVdjdocl3xI Hallmarks of aging – time for a paradigm shift? https://i.ytimg.com/vi/zVdjdocl3xI/hqdefault.jpg If you’re like me, then possibly your first introduction to the field of biogerontology is the 2013 review articles “The hallmarks of aging” by Lopez-Otin et al. This most cited review in the field of aging defines common denominators of aging in different organisms into 9 different hallmarks and is a pretty common reference point for the field. I’ve always liked the hallmarks as an introduction to the field, so much so that I described the hallmarks in some of my earliest videos. Speaking of my earliest videos, given that it’s almost my 2-year birthday on YouTube, I’d thought I’d revisit the hallmarks of aging given that there has been some recent criticism on them suggesting that maybe we should start to look beyond them. So in this video, I’ll first explain why models and paradigms are useful and then show you the different models used to explain aging (as the hallmarks is not the only model), will then look at the limitations of the hallmarks as discussed in this recent critique paper and lastly look at their solution and see if it is time for a paradigm shift. And just to let you know, I have also made this video in tandem with @LongevityScienceNews show whose video you can check out here; https://www.youtube.com/watch?v=DiufT9dvSaI TIMESTAMPS Intro - 00:00 Scientific Paradigms (Thomas Kuhn) - 01:10 Hallmarks of aging - 03:00 Hallmarks of cancer - 06:20 Issues with the hallmarks - 08:20 How to improve the hallmarks - 09:50 My thoughts - 11:00 References: The Hallmarks of Aging - https://doi.org/10.1016/j.cell.2013.05.039 Gems, D.; de Magalhães, J.P. The Hoverfly and the Wasp: A Critique of the Hallmarks of Aging as a Paradigm. Preprints 2021, 2021050310 (doi: 10.20944/preprints202105.0310.v1). The Hallmarks of Cancer - https://doi.org/10.1016/S0092-8674(00)81683-9 Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com https://www.youtube-nocookie.com/embed/zVdjdocl3xI 786 2021-06-11T15:00:28.000Z 2026-10-22T17:43:40.166Z https://longevityharbor.com/en/watch/zVpGrKqCoQc Länger leben mit NMN? (wissenschaftlich untersucht!) https://i.ytimg.com/vi/zVpGrKqCoQc/hqdefault.jpg In diesem Video schauen wir uns zusammen NMN als eine potentielle Langlebigkeitssubstanz an. Zeitmarken: 00:00 Einleitung 02:16 Funktion von NMN im Körper 06:38 NMN Supplementierung 07:45 Einfache Tipps & Tricks ========================================================================= Unsere Webseite: https://www.cellventrix.com Impressum: https://www.cellventrix.com/impressum Musik: Anthem of Inspiration, RomanSenykMusic/Pond5.com (Stock-Musik) Haftungsausschluss: Die hier angebotenen Inhalte dienen ausschließlich der allgemeinen Information und persönlichen Weiterbildung. Die Inhalte dieses Videos sind sauber recherchiert. Es kann jedoch nicht ausgeschlossen werden, dass sich Fehler eingeschlichen haben. Die Inhalte erheben keinen Anspruch auf Vollständigkeit. Sie ersetzen in keinem Fall die persönliche Beratung durch einen Arzt oder eine qualifizierte medizinische Fachkraft. Es wird keine Haftung übernommen für Schäden oder Unannehmlichkeiten, die als Folge dieser Inhalte entstanden sind. https://www.youtube-nocookie.com/embed/zVpGrKqCoQc 702 2024-02-04T08:22:47.000Z 2026-10-22T17:43:42.535Z https://longevityharbor.com/de/watch/zVpGrKqCoQc Länger leben mit NMN? (wissenschaftlich untersucht!) https://i.ytimg.com/vi/zVpGrKqCoQc/hqdefault.jpg In diesem Video schauen wir uns zusammen NMN als eine potentielle Langlebigkeitssubstanz an. Zeitmarken: 00:00 Einleitung 02:16 Funktion von NMN im Körper 06:38 NMN Supplementierung 07:45 Einfache Tipps & Tricks ========================================================================= Unsere Webseite: https://www.cellventrix.com Impressum: https://www.cellventrix.com/impressum Musik: Anthem of Inspiration, RomanSenykMusic/Pond5.com (Stock-Musik) Haftungsausschluss: Die hier angebotenen Inhalte dienen ausschließlich der allgemeinen Information und persönlichen Weiterbildung. Die Inhalte dieses Videos sind sauber recherchiert. Es kann jedoch nicht ausgeschlossen werden, dass sich Fehler eingeschlichen haben. Die Inhalte erheben keinen Anspruch auf Vollständigkeit. Sie ersetzen in keinem Fall die persönliche Beratung durch einen Arzt oder eine qualifizierte medizinische Fachkraft. Es wird keine Haftung übernommen für Schäden oder Unannehmlichkeiten, die als Folge dieser Inhalte entstanden sind. https://www.youtube-nocookie.com/embed/zVpGrKqCoQc 702 2024-02-04T08:22:47.000Z 2026-10-22T17:43:42.535Z https://longevityharbor.com/en/watch/zXsT5hxAqv8 Here’s how NMN can help boost NAD levels and how to choose a great quality supplement! #nmn https://i.ytimg.com/vi/zXsT5hxAqv8/hqdefault.jpg Here’s how NMN can help boost NAD levels and how to choose a great quality supplement! #nmn #newyearnewme #antiaging #tiktokshopcreatorpicks #over40 https://www.youtube-nocookie.com/embed/zXsT5hxAqv8 126 2026-10-05T15:12:10.000Z 2026-10-22T17:43:42.544Z https://longevityharbor.com/de/watch/zXsT5hxAqv8 Here’s how NMN can help boost NAD levels and how to choose a great quality supplement! #nmn https://i.ytimg.com/vi/zXsT5hxAqv8/hqdefault.jpg Here’s how NMN can help boost NAD levels and how to choose a great quality supplement! #nmn #newyearnewme #antiaging #tiktokshopcreatorpicks #over40 https://www.youtube-nocookie.com/embed/zXsT5hxAqv8 126 2026-10-05T15:12:10.000Z 2026-10-22T17:43:42.544Z https://longevityharbor.com/en/watch/z_FGe_N95Bo Video description: Kaeberlein on biological age, mTOR, rapamycin and longevity hype https://i.ytimg.com/vi/z_FGe_N95Bo/hqdefault.jpg In the description, aging scientist Matt Kaeberlein is presented as discussing biological age, mTOR, rapamycin, GLP-1s, supplements, peptides and the Dog Aging Project, and naming exercise, sleep, nutrition and social connection as the biggest levers for healthspan. https://www.youtube-nocookie.com/embed/z_FGe_N95Bo 6139 2026-08-07T13:30:06.000Z 2026-10-22T23:13:25.837Z https://longevityharbor.com/de/watch/z_FGe_N95Bo Videobeschreibung: Kaeberlein über biologisches Alter, mTOR, Rapamycin und Longevity-Hype https://i.ytimg.com/vi/z_FGe_N95Bo/hqdefault.jpg In der Beschreibung wird der Alternsforscher Matt Kaeberlein so vorgestellt, dass er biologisches Alter, mTOR, Rapamycin, GLP-1-Präparate, Nahrungsergänzungsmittel, Peptide und das Dog Aging Project bespricht und Bewegung, Schlaf, Ernährung und soziale Verbundenheit als größte Hebel für die Gesundheitsspanne nennt. https://www.youtube-nocookie.com/embed/z_FGe_N95Bo 6139 2026-08-07T13:30:06.000Z 2026-10-22T23:13:25.837Z https://longevityharbor.com/en/watch/zch0CqHuSOI Longevity Labs video description on blue light, sleep and biohacking topics https://i.ytimg.com/vi/zch0CqHuSOI/hqdefault.jpg The description of this Longevity Labs video names blue light and sleep in its title and lists sleep science, circadian rhythm and biological age among the channel's topics. It gives no study results, numbers or protocols; the video and transcript were not reviewed. https://www.youtube-nocookie.com/embed/zch0CqHuSOI 951 2026-01-31T13:31:12.000Z 2026-10-23T02:41:42.345Z https://longevityharbor.com/de/watch/zch0CqHuSOI Longevity-Labs-Videobeschreibung zu Blaulicht, Schlaf und Biohacking-Themen https://i.ytimg.com/vi/zch0CqHuSOI/hqdefault.jpg Die Beschreibung dieses Longevity-Labs-Videos nennt Blaulicht und Schlaf im Titel und führt Schlafwissenschaft, zirkadianen Rhythmus und biologisches Alter unter den Themen des Kanals. Sie enthält keine Studienergebnisse, Zahlen oder Protokolle; Video und Transkript wurden nicht geprüft. https://www.youtube-nocookie.com/embed/zch0CqHuSOI 951 2026-01-31T13:31:12.000Z 2026-10-23T02:41:42.345Z https://longevityharbor.com/en/watch/zgAjInpDYEs NMN video description: disclaimer and topic tags only https://i.ytimg.com/vi/zgAjInpDYEs/hqdefault.jpg The description of this NMN video contains only a disclaimer, a note that the information reflects the state of research at publication in 2026, and hashtags such as NMN, NAD and longevity. It reports no study, results or safety findings. https://www.youtube-nocookie.com/embed/zgAjInpDYEs 92 2026-03-16T22:31:42.000Z 2026-10-23T02:00:20.328Z https://longevityharbor.com/de/watch/zgAjInpDYEs NMN-Videobeschreibung: nur Haftungsausschluss und Themen-Tags https://i.ytimg.com/vi/zgAjInpDYEs/hqdefault.jpg Die Beschreibung dieses NMN-Videos enthält nur einen Haftungsausschluss, den Hinweis auf den Forschungsstand zum Veröffentlichungszeitpunkt 2026 und Hashtags wie NMN, NAD und Longevity. Sie berichtet keine Studie, keine Ergebnisse und keine Sicherheitsbefunde. https://www.youtube-nocookie.com/embed/zgAjInpDYEs 92 2026-03-16T22:31:42.000Z 2026-10-23T02:00:20.328Z https://longevityharbor.com/en/watch/zhcBSoue4hs Doctor's video description on nutrients claimed to slow aging from age 30 https://i.ytimg.com/vi/zhcBSoue4hs/hqdefault.jpg In the description, the doctor says nutrients and bioactive substances such as secondary plant compounds may help people stay fit and partly counter natural aging, but cannot stop aging. He lists omega-3 fatty acids, vitamin D, coenzyme Q10, vitamins C and E, polyphenols, magnesium, B vitamins, zinc, selenium, protein and antioxidants. https://www.youtube-nocookie.com/embed/zhcBSoue4hs 1169 2025-12-22T16:15:06.000Z 2026-10-23T03:14:14.116Z https://longevityharbor.com/de/watch/zhcBSoue4hs Arzt-Videobeschreibung zu Nährstoffen, die ab 30 das Altern bremsen sollen https://i.ytimg.com/vi/zhcBSoue4hs/hqdefault.jpg In der Beschreibung sagt der Arzt, Nährstoffe und bioaktive Substanzen wie sekundäre Pflanzenstoffe könnten helfen, lange fit zu bleiben und dem natürlichen Altern teilweise entgegenzuwirken; aufhalten lasse sich das Altern aber nicht. Er nennt Omega-3-Fettsäuren, Vitamin D, Coenzym Q10, Vitamin C und E, Polyphenole, Magnesium, B-Vitamine, Zink, Selen, Proteine und Antioxidantien. https://www.youtube-nocookie.com/embed/zhcBSoue4hs 1169 2025-12-22T16:15:06.000Z 2026-10-23T03:14:14.116Z https://longevityharbor.com/en/watch/ziSI62AFA5I Does Fasting Really Extend Your Life? — A Top Aging Scientist Weighs In https://i.ytimg.com/vi/ziSI62AFA5I/hqdefault.jpg For nearly a century, one intervention has shown more consistent promise in aging research than almost any diet trend: eating less. In this clip, Dr. Pankaj Kapahi of the Buck Institute for Research on Aging explains why dietary restriction extends lifespan in the lab — and why there's no single "fasting pill" that works the same for everyone. We get into the metabolic shift from burning sugar to burning fat, the glycation process that has our bodies slowly "toasting" with age, and the everyday habits the research points toward: a 10–12 hour eating window, more fiber, fewer simple carbohydrates, whole foods, and the Japanese principle of eating to roughly 80% full. What works depends on age, sex, metabolism, and health history, and the science here is still evolving. This isn't medical advice — evidence is suggestive, not prescriptive, so talk with your physician before changing how or when you eat. CHAPTERS: 00:00 Beyond the diet noise 00:21 Dr. Pankaj Kapahi: why dietary restriction extends lifespan 01:06 Why there's no universal "fasting pill" 01:48 Metabolic flexibility and aging 02:03 The Warburg effect: burning sugar vs. fat 02:37 Glycation and AGEs: how the body "toasts" with age 03:16 What the research points to: timing, fiber, and the 80% rule ABOUT FOREVER YOUNG Forever Young is an award-winning documentary that provides insider access to the longevity revolution — and the deeply human questions it forces us to face. The film features leading aging researchers from across the globe. ▶ Watch the trailer: https://youtu.be/gT2V-USKm6g ▶ Coming to Apple TV on May 26th https://tv.apple.com/us/movie/forever-young/umc.cmc.4t1561uviumw4ofcri0ufql7v ▶ Go deeper on the science at our Substack: https://foreveryoungfilm.substack.com ▶ More about the film: https://foreveryoung.film ▶ Instagram: @foreveryoungdoc #Longevity #Fasting #ForeverYoung #HealthyAging #CaloricRestriction https://www.youtube-nocookie.com/embed/ziSI62AFA5I 237 2026-05-18T09:18:04.000Z 2026-10-22T18:32:09.907Z https://longevityharbor.com/de/watch/ziSI62AFA5I Does Fasting Really Extend Your Life? — A Top Aging Scientist Weighs In https://i.ytimg.com/vi/ziSI62AFA5I/hqdefault.jpg For nearly a century, one intervention has shown more consistent promise in aging research than almost any diet trend: eating less. In this clip, Dr. Pankaj Kapahi of the Buck Institute for Research on Aging explains why dietary restriction extends lifespan in the lab — and why there's no single "fasting pill" that works the same for everyone. We get into the metabolic shift from burning sugar to burning fat, the glycation process that has our bodies slowly "toasting" with age, and the everyday habits the research points toward: a 10–12 hour eating window, more fiber, fewer simple carbohydrates, whole foods, and the Japanese principle of eating to roughly 80% full. What works depends on age, sex, metabolism, and health history, and the science here is still evolving. This isn't medical advice — evidence is suggestive, not prescriptive, so talk with your physician before changing how or when you eat. CHAPTERS: 00:00 Beyond the diet noise 00:21 Dr. Pankaj Kapahi: why dietary restriction extends lifespan 01:06 Why there's no universal "fasting pill" 01:48 Metabolic flexibility and aging 02:03 The Warburg effect: burning sugar vs. fat 02:37 Glycation and AGEs: how the body "toasts" with age 03:16 What the research points to: timing, fiber, and the 80% rule ABOUT FOREVER YOUNG Forever Young is an award-winning documentary that provides insider access to the longevity revolution — and the deeply human questions it forces us to face. The film features leading aging researchers from across the globe. ▶ Watch the trailer: https://youtu.be/gT2V-USKm6g ▶ Coming to Apple TV on May 26th https://tv.apple.com/us/movie/forever-young/umc.cmc.4t1561uviumw4ofcri0ufql7v ▶ Go deeper on the science at our Substack: https://foreveryoungfilm.substack.com ▶ More about the film: https://foreveryoung.film ▶ Instagram: @foreveryoungdoc #Longevity #Fasting #ForeverYoung #HealthyAging #CaloricRestriction https://www.youtube-nocookie.com/embed/ziSI62AFA5I 237 2026-05-18T09:18:04.000Z 2026-10-22T18:32:09.907Z https://longevityharbor.com/en/watch/zkTDTQrNIr8 Talk description: Horvath on epigenetic clocks and biological ageing https://i.ytimg.com/vi/zkTDTQrNIr8/hqdefault.jpg According to the description, Steve Horvath gave an in-person talk on epigenetic clocks, biological ageing and longevity, covering what clocks such as PhenoAge and GrimAge have revealed about biological age, ageing trajectories, and the impact of lifestyle, environment and chronic disease. https://www.youtube-nocookie.com/embed/zkTDTQrNIr8 6118 2026-03-18T08:55:49.000Z 2026-10-23T02:00:12.437Z https://longevityharbor.com/de/watch/zkTDTQrNIr8 Vortragsbeschreibung: Horvath über epigenetische Uhren und biologisches Altern https://i.ytimg.com/vi/zkTDTQrNIr8/hqdefault.jpg Laut Beschreibung hielt Steve Horvath einen Präsenzvortrag über epigenetische Uhren, biologisches Altern und Langlebigkeit. Behandelt wurde, was Uhren wie PhenoAge und GrimAge über biologisches Alter, Alternsverläufe sowie den Einfluss von Lebensstil, Umwelt und chronischen Erkrankungen gezeigt haben. https://www.youtube-nocookie.com/embed/zkTDTQrNIr8 6118 2026-03-18T08:55:49.000Z 2026-10-23T02:00:12.437Z https://longevityharbor.com/en/watch/zksfXVkYw-w Epigenetic clocks: model outputs, not a second birthday https://i.ytimg.com/vi/zksfXVkYw-w/hqdefault.jpg The description says an epigenetic clock applies a statistical model to specimen measurements; it does not directly count the age of every body part. Repeatability, biological variation and a changed score need different evidence. https://www.youtube-nocookie.com/embed/zksfXVkYw-w 152 2026-09-21T22:00:29.000Z 2026-10-22T21:58:38.414Z https://longevityharbor.com/de/watch/zksfXVkYw-w Epigenetische Uhren: Modellwerte, kein zweiter Geburtstag https://i.ytimg.com/vi/zksfXVkYw-w/hqdefault.jpg Laut Beschreibung wendet eine epigenetische Uhr ein statistisches Modell auf Messungen einer Probe an; sie zählt nicht direkt das Alter jedes Körperteils. Wiederholbarkeit, biologische Variation und ein veränderter Wert brauchen unterschiedliche Belege. https://www.youtube-nocookie.com/embed/zksfXVkYw-w 152 2026-09-21T22:00:29.000Z 2026-10-22T21:58:38.414Z https://longevityharbor.com/en/watch/zla42AW-rYI The Role of mTOR in Neurodegenerative Disorders: Exploring the Therapeutic Potential of Rapamycin https://i.ytimg.com/vi/zla42AW-rYI/hqdefault.jpg In this video, we dive deep into the molecular intricacies of mTOR pathways and their potentially profound implications in neurodegenerative diseases. Moreover, we delve into the therapeutic promise of rapamycin, a molecule that may herald a paradigm shift in neurodegenerative disease management and prophylaxis. To learn more visit our blog at https://gethealthspan.com/science sign up for healthspan now: https://gethealthspan.com/ To stay up to date with all the latest longevity research follow us on all our channels https://twitter.com/healthspanmed https://www.instagram.com/healthspan/ join our community: https://community.gethealthspan.com/faq https://www.youtube-nocookie.com/embed/zla42AW-rYI 516 2024-01-24T22:06:27.000Z 2026-10-22T18:43:07.195Z https://longevityharbor.com/de/watch/zla42AW-rYI The Role of mTOR in Neurodegenerative Disorders: Exploring the Therapeutic Potential of Rapamycin https://i.ytimg.com/vi/zla42AW-rYI/hqdefault.jpg In this video, we dive deep into the molecular intricacies of mTOR pathways and their potentially profound implications in neurodegenerative diseases. Moreover, we delve into the therapeutic promise of rapamycin, a molecule that may herald a paradigm shift in neurodegenerative disease management and prophylaxis. To learn more visit our blog at https://gethealthspan.com/science sign up for healthspan now: https://gethealthspan.com/ To stay up to date with all the latest longevity research follow us on all our channels https://twitter.com/healthspanmed https://www.instagram.com/healthspan/ join our community: https://community.gethealthspan.com/faq https://www.youtube-nocookie.com/embed/zla42AW-rYI 516 2024-01-24T22:06:27.000Z 2026-10-22T18:43:07.195Z https://longevityharbor.com/en/watch/zs1a8tFsvdc 18 Longevity Secrets to Live a Healthy 100 Years https://i.ytimg.com/vi/zs1a8tFsvdc/hqdefault.jpg Living to 100 isn’t just about good genes. I’ll share 18 science-backed longevity tips you can start today to boost your chances of living to 100 years and beyond. Just so you know, my full line of high-quality supplements is available on Amazon — search Dr. Berg Supplements. 👉 Get Dr.Berg’s Daily Routine as a free download: https://drbrg.co/49fboC1 HOW TO MAKE L. REUTERI YOGURT: ➡️ https://drbrg.co/46bMQqU [Affiliate links] Yogurt Maker: https://amzn.to/4k1LO71 Yogurt Jars: https://amzn.to/411hSPw Yogurt Containers: https://amzn.to/411eXX0 Curious about prolonged fasting? Watch my other videos to learn more: ▶️ https://youtu.be/O1zKV3eqevc ▶️ https://youtu.be/ig3l3I4PARA ▶️ https://youtu.be/EX_kg6Nimbc ▶️ https://youtu.be/06KgXfwu99c What else can hypoxia training do? Find out here: ▶️ https://youtu.be/3QVPkrYO57g Discover the importance of testosterone here: ▶️ https://youtu.be/Ap90NXxSS0g ▶️ https://youtu.be/Tqwvm5RsHRM 0:00 Introduction: How to live to 100 years old 1:18 Did medicine and science slow aging and help extend life? 4:19 Focus on healthy living to stop aging 6:20 The country where more people live to 100 than anywhere else 7:05 Japan’s longevity secrets 14:37 The Blue Zones of longevity 15:49 18 scientifically proven tips for living a long life DATA: https://www.theguardian.com/science/2022/dec/09/academy-nutrition-financial-ties-processed-food-companies-contributions https://www.eviemagazine.com/post/influencer-dietitians-paid-off-corrupt-companies-promote-unhealthy-foods There are various areas across the globe known as the Blue Zones where more people live for more than 100 years than anywhere else. I wanted to know what’s their secret and how can I live for a long time? The dietary and lifestyle patterns in these Blue Zones offer fascinating insight into habits that can help reverse aging and support life well beyond 100 years. Japan has the most centenarians in the world, thanks to a powerful mix of a longevity diet and a healthy lifestyle. This includes fermente https://www.youtube-nocookie.com/embed/zs1a8tFsvdc 1967 2025-09-06T11:01:44.000Z 2026-10-22T18:43:11.748Z https://longevityharbor.com/de/watch/zs1a8tFsvdc 18 Longevity Secrets to Live a Healthy 100 Years https://i.ytimg.com/vi/zs1a8tFsvdc/hqdefault.jpg Living to 100 isn’t just about good genes. I’ll share 18 science-backed longevity tips you can start today to boost your chances of living to 100 years and beyond. Just so you know, my full line of high-quality supplements is available on Amazon — search Dr. Berg Supplements. 👉 Get Dr.Berg’s Daily Routine as a free download: https://drbrg.co/49fboC1 HOW TO MAKE L. REUTERI YOGURT: ➡️ https://drbrg.co/46bMQqU [Affiliate links] Yogurt Maker: https://amzn.to/4k1LO71 Yogurt Jars: https://amzn.to/411hSPw Yogurt Containers: https://amzn.to/411eXX0 Curious about prolonged fasting? Watch my other videos to learn more: ▶️ https://youtu.be/O1zKV3eqevc ▶️ https://youtu.be/ig3l3I4PARA ▶️ https://youtu.be/EX_kg6Nimbc ▶️ https://youtu.be/06KgXfwu99c What else can hypoxia training do? Find out here: ▶️ https://youtu.be/3QVPkrYO57g Discover the importance of testosterone here: ▶️ https://youtu.be/Ap90NXxSS0g ▶️ https://youtu.be/Tqwvm5RsHRM 0:00 Introduction: How to live to 100 years old 1:18 Did medicine and science slow aging and help extend life? 4:19 Focus on healthy living to stop aging 6:20 The country where more people live to 100 than anywhere else 7:05 Japan’s longevity secrets 14:37 The Blue Zones of longevity 15:49 18 scientifically proven tips for living a long life DATA: https://www.theguardian.com/science/2022/dec/09/academy-nutrition-financial-ties-processed-food-companies-contributions https://www.eviemagazine.com/post/influencer-dietitians-paid-off-corrupt-companies-promote-unhealthy-foods There are various areas across the globe known as the Blue Zones where more people live for more than 100 years than anywhere else. I wanted to know what’s their secret and how can I live for a long time? The dietary and lifestyle patterns in these Blue Zones offer fascinating insight into habits that can help reverse aging and support life well beyond 100 years. Japan has the most centenarians in the world, thanks to a powerful mix of a longevity diet and a healthy lifestyle. This includes fermente https://www.youtube-nocookie.com/embed/zs1a8tFsvdc 1967 2025-09-06T11:01:44.000Z 2026-10-22T18:43:11.748Z https://longevityharbor.com/en/watch/zuf6Bw4hGCk 51 intervention studies: epigenetic clocks respond, per a Yale-led analysis https://i.ytimg.com/vi/zuf6Bw4hGCk/hqdefault.jpg The description says a Yale-led analysis of 51 longitudinal intervention studies found epigenetic clocks, especially mortality- or pace-of-aging-trained ones, respond to interventions; this is described as a basis for surrogate endpoints, not proof of longer life. https://www.youtube-nocookie.com/embed/zuf6Bw4hGCk 2990 2026-08-25T18:00:06.000Z 2026-10-22T22:46:37.725Z https://longevityharbor.com/de/watch/zuf6Bw4hGCk 51 Interventionsstudien: epigenetische Uhren reagieren laut Yale-geführter Analyse https://i.ytimg.com/vi/zuf6Bw4hGCk/hqdefault.jpg Laut Beschreibung fand eine Yale-geführte Analyse von 51 longitudinalen Interventionsstudien, dass epigenetische Uhren – besonders auf Sterblichkeit oder Alterungstempo trainierte – auf Interventionen reagieren; dies wird als Grundlage für Surrogatendpunkte beschrieben, nicht als Beweis für ein längeres Leben. https://www.youtube-nocookie.com/embed/zuf6Bw4hGCk 2990 2026-08-25T18:00:06.000Z 2026-10-22T22:46:37.725Z https://longevityharbor.com/en/watch/zz_DVkg_zsA The role of epigenetics in aging | Peter Attia and Alex Aravanis https://i.ytimg.com/vi/zz_DVkg_zsA/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/9RaQyvI-Rgg Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 290 - Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the more with Alex Aravanis, M.D., Ph.D. Alex Aravanis is a leader in research and development of technologies and clinical tests utilizing the latest tools in DNA analysis and data science. In this clip, Alex and Peter discuss: - A primer on methylation of our genome - Why epigenetic alterations are one of the 12 hallmarks of aging - Lifestyle factors that influence epigenetic changes - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not https://www.youtube-nocookie.com/embed/zz_DVkg_zsA 444 2024-02-21T17:00:48.000Z 2026-10-22T17:43:39.301Z https://longevityharbor.com/de/watch/zz_DVkg_zsA The role of epigenetics in aging | Peter Attia and Alex Aravanis https://i.ytimg.com/vi/zz_DVkg_zsA/hqdefault.jpg Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/9RaQyvI-Rgg Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 290 - Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the more with Alex Aravanis, M.D., Ph.D. Alex Aravanis is a leader in research and development of technologies and clinical tests utilizing the latest tools in DNA analysis and data science. In this clip, Alex and Peter discuss: - A primer on methylation of our genome - Why epigenetic alterations are one of the 12 hallmarks of aging - Lifestyle factors that influence epigenetic changes - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. 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