Spermidine & Autophagy: The Key to Healthy Aging | Leslie Kenny

Save 20% off your first Oxford Healthspan order with code CYNTHIATHURLOW: https://www.oxfordhealthspan.com/CYNTHIATHURLOW 🎙️ What if one of the keys to healthy aging lies in your body’s ability to clean up and recycle damaged cellular components? In this BONUS episode of the Everyday Wellness Podcast, Cynthia Thurlow sits down with Leslie Kenny, Oxford-based longevity entrepreneur, healthspan advocate, founder of Oxford Healthspan, creator of Primeadine®, and co-founder of the Oxford Longevity Project. After being diagnosed with rheumatoid arthritis and lupus and being told she was unlikely to have biological children, Leslie began exploring nutrition and lifestyle changes and later conceived naturally at age 43. Her personal health journey eventually led to a research collaboration with Oxford immunologist Professor Katya Simon, where Leslie was introduced to spermidine and its relationship with autophagy—the body’s cellular recycling and cleanup process. In this fascinating conversation, Cynthia and Leslie explore the emerging science of spermidine, autophagy, mitophagy, cellular health, healthy aging, and longevity. They also discuss gut health, intermittent fasting, circadian biology, perimenopause and menopause, biological versus chronological age, and the lifestyle habits that may help support healthspan as we age. Highlights from this conversation: ✨ Leslie’s nutrition and lifestyle changes after her rheumatoid arthritis and lupus diagnoses ✨ Why self-advocacy and collaboration with your healthcare team matter ✨ Navigating symptoms during the transition from perimenopause to menopause ✨ Spermidine and its connection to autophagy and cellular renewal ✨ The difference between autophagy and mitophagy ✨ Spermidine’s emerging role in healthy aging and longevity research ✨ How spermidine levels change with age and its natural food sources ✨ The relationship between gut health, ultra-processed foods, and spermidine ✨ Reported benefits of Primeadine® for memory, cognition, hair, skin, and nails ✨ The difference between biological age and chronological age ✨ How clock genes and circadian biology influence health and aging ✨ Why intermittent fasting may affect women differently ✨ Muscle, sleep, stress reduction, and whole foods for healthy aging 🌿 One of the biggest takeaways: Healthy aging is not about one supplement, one diet, or one intervention. The everyday choices we make—building muscle, eating whole foods, prioritizing sleep, managing stress, and supporting our body’s natural cellular processes—can compound over time. 🎧 Watch the full conversation with Leslie Kenny to learn more about spermidine, autophagy, cellular renewal, intermittent fasting, and the science of supporting a longer, healthier life. About Leslie Kenny Leslie Kenny is an Oxford-based longevity entrepreneur, TEDx Oxford speaker, and healthspan advocate. She is the founder of Oxford Healthspan, creator of Primeadine®, co-founder of the Oxford Longevity Project, and Global Executive Ambassador for the Japan Autophagy Consortium. Leslie is a frequent international speaker and moderator on longevity, biological aging, and the future of preventive medicine, with a particular focus on translating emerging research into practical, evidence-based strategies for extending healthspan. GET CYNTHIA THURLOW’S BOOK The Menopause Gut is available here: → https://www.cynthiathurlow.com/the-menopause-gut/ SHOP CYNTHIA’S SUPPLEMENTS The supplements I formulated for women in midlife, from The Midlife Pause: → https://themidlifepause.com Connect with Leslie Kenny Oxford Longevity Project: →https://oxfordlongevityproject.org/ Oxford Healthspan: → https://oxfordhealthspan.com/ Save 20% off your first Oxford Healthspan order with code CYNTHIATHURLOW: → https://www.oxfordhealthspan.com/CYNTHIATHURLOW Leslie’s New Prime: → https://lesliesnewprime.com/ For more information please visit me here: https://cynthiathurlow.com/ This video is for educational and informational purposes only and solely as a self-help tool for your own use. I am not providing medical, psychological, or nutrition therapy advice. You should not use this information to diagnose or treat any health problems or illnesses without consulting your own medical practitioner. Always seek the advice of your own medical practitioner and/or mental health provider about your specific health situation.