Creatine Fights Brain Aging's Energy Crisis | Dr Dan Pardi

Dr. Dan Pardi explains how declining cellular energy is a core driver of brain aging—and why creatine, NAD+, and urolithin A target this mechanism Some links are affiliate links so we will earn a commission when they are used to purchase products. If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan ~~~~~~~~~~~~~~ *Qualia* (15% off: MODERN) Creatine+ https://tinyurl.com/mr3z35jd MIND https://tinyurl.com/3j3xmrhw Senolytic https://bit.ly/4jlaibe These are affiliate links - using them supports the channel at no extra cost to you. ~~~~~~~~~~~~~~ One of the core hallmarks of aging is declining energy production. Your mitochondria become less efficient, NAD+ levels drop by 50% by your 50s, and every cell in your body struggles to maintain the energy needed for basic functions. Dr. Dan Pardi explains why this matters especially for the brain—and why a multi-pronged energy support strategy makes sense. He covers how creatine acts as an energy buffer (not a source), how it complements NAD+ support and urolithin A for mitochondrial health, and why gut integrity problems in aging are fundamentally energy problems. The key insight: creatine doesn't fix the root cause of declining mitochondrial function, but it helps cells maintain performance despite it. Combined with other interventions targeting energy metabolism, it may help preserve cognitive function longer. This is the biological rationale for why older adults may benefit from creatine supplementation, even without direct clinical trials yet. 📚 Chapters 0:00 - Energy Decline: The Core Aging Problem 2:15 - NAD+ Decline and Mitochondrial Dysfunction 3:45 - How Creatine Facilitates Energy Transfer in Cells 5:00 - Gut Integrity: An Energy Problem in Aging 6:30 - Leaky Gut, Oxygen, and Dysbiosis 7:15 - Why We Need More Research in Older Adults 8:45 - The 89-Year-Old Question: Safety Across Age Groups 🌐Links in this video Qualia Life Sciences web page https://www.qualialife.com/ Human OS website https://humanos.me/ #creatine #jetlag #longevity