Lucy Costantino | Emerging Technologies Shaping Longevity | Milan Longevity Summit 2026

*Epigenetic Regulation of Aging* If our DNA stays largely the same throughout life, why does the way our genes behave change as we age? In this session from *Emerging Technologies Shaping Longevity* at the *Milan Longevity Summit 2026*, *Dr. Lucy Costantino* explores epigenetic regulation and its fundamental role in the biology of ageing. Epigenetic mechanisms influence which genes are activated or silenced without altering the underlying DNA sequence. Over time, these regulatory patterns change, affecting cellular identity, repair, metabolism, inflammation, and other processes associated with ageing and age-related disease. Dr. Costantino examines how understanding these changes can provide new insights into biological age, individual health trajectories, and the development of increasingly personalised approaches to prevention and longevity medicine. Dr. Lucy Costantino is a geneticist at *Centro Diagnostico Italiano (CDI)*, where her work focuses on genetics, molecular diagnostics, and the application of genomic and epigenetic knowledge to human health. The Milan Longevity Summit brings together global leaders across science, medicine, policy, business, technology and society to rethink the future of health through a *One Health* perspective—recognising that the wellbeing of people, planet and economies is deeply interconnected. *Learn more about the Milan Longevity Summit:* https://www.milanlongevitysummit.org/it/speakers26/lucy-costantino #MilanLongevitySummit #Longevity #OneHealth #LucyCostantino #Epigenetics #Genetics #BiologicalAge #PrecisionMedicine #HealthyAgeing #Healthspan