The Real Reason You Age (And How to Slow It Down) | Dr. Eric Verdin & Dr. Mark Hyman

Discover the real reason you age and exactly how to slow it down. Dr. Mark Hyman and Dr. Eric Verdin reveal why aging is the root cause of chronic disease and how to reverse it. We tend to think of heart disease, cancer, and Alzheimer’s as completely separate problems. But what if they all stem from the exact same underlying process? In this episode, I sit down with Dr. Eric Verdin, President and CEO of the Buck Institute for Research on Aging, to discuss the "geroscience hypothesis" and why targeting your biological age is the ultimate secret to long-term health. We explore the fascinating connection between "inflammaging"—how your immune system becomes both overactive and less effective over time—and the decline of cellular energy. Dr. Verdin breaks down exactly what chronic inflammation is doing inside your body, how your gut microbiome and mitochondria constantly communicate, and why taking care of these cellular energy factories is crucial for repair and recovery. Moving beyond treating symptoms to fixing the root cause, we also dive into the daily habits that actually impact longevity. From eating the right prebiotics to feed your gut, to the science behind compounds like Urolithin A (and how it revitalizes your T-cells), this conversation will completely reshape how you approach aging. The waitlist is open! Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health - https://drhyman.com/pages/brainshaping-academy-waitlist?utm_source=Podcast&utm_medium=YouTube&utm_campaign=brainshaping-waitlist View Show Notes From This Episode https://drhyman.com/blogs/content/podcast-ep1139 Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, Seed, BIOptimizers, BON CHARGE, Paleovalley and Big Bold Health. Visit https://timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Go to https://seed.com/hyman and use code 20HYMAN to get 20% off your first month. Head to https://bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Head to https://boncharge.com/hyman and use code HYMAN for 15% off. Head to https://paleovalley.com/hyman to save 15% off your first order today. Go to https://bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. #Longevity #DrMarkHyman #Inflammaging #AntiAging #Mitochondria (0:00) Targeting aging and its role as the biggest risk factor for chronic diseases (2:12) Conservative approach to longevity medicine and primary features of aging (3:21) Geoscience hypothesis and unmodifiable risk factors (age, gender) (5:23) Aging as the root cause of diseases and realistic life extension projections (10:20) Acute vs. chronic inflammation (13:44) Mitochondria, inflammation, and hallmarks of aging (17:02) Mitochondria as bacterial descendants and immune response to mitochondrial DNA (19:02) Bidirectional effects of inflammation and mitochondria, immune system decline (20:31) Innate and adaptive immune systems explained (24:23) Impact of aging on immune response and vaccinations (26:22) Importance of maintaining immune health (29:42) Organs as predictors of lifespan and mitigating inflammation (33:04) Gut health, fiber intake, and microbiome in longevity (37:04) Foundations of longevity medicine and social connections affecting immunity (40:28) Mitochondria, cellular energy, and repair mechanisms in aging (45:22) Energy allocation, postbiotics, and cellular health (49:51) Urolithin A’s impact on mitochondrial function and immunity (1:00:07) Longevity interventions, systemic medicine, and functional medicine integration (1:02:57) Advances in medical data, biological age, and health monitoring (1:09:36) Future of continuous health monitoring and episode conclusion What if you could change your biological age to some degree? The video discusses how aging is a primary driver of diseases like heart attack and stroke, making age a more significant factor than cholesterol for heart health. This means targeting aging could have a substantial impact on your risk for heart disease, fundamentally shifting our approach to cardiovascular health and how to live longer.