The Mitochondrial Supplement in The XPRIZE Semi-Finals | Dr Anurag Singh

Dr. Anurag Singh discusses urolithin A's Healthspan XPrize semi-finalist status, ongoing blood-brain barrier research, and future brain health trials. Learn about mitochondrial transplantation, mitophagy biomarkers, and why mitochondrial dysfunction may be the root cause of aging. Some links are affiliate links so we will earn a commission when they are used to purchase products. If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan ~~~~~~~~~~~~~~ Time-Line Mitopure Urolithin A, 10% off Code MODERN https://timeline.sjv.io/k4JrNx ~~~~~~~~~~~~~~ Timeline and urolithin A are semi-finalists in the $80 million Healthspan XPrize. Dr. Anurag Singh reveals they're currently testing whether urolithin A penetrates the blood-brain barrier - the critical first step before brain health trials. He discusses upcoming neurodegeneration research with leading scientists and the challenge of developing practical mitophagy biomarkers. Dr Singh also explores the future of mitochondrial medicine, including mitochondrial transplantation and how it might combine with mitophagy activation. He agrees with Dr. Luigi Ferrucci that mitochondrial dysfunction is "the mother of all hallmarks of aging" - the central station in the aging process. If you're interested in the cutting edge of longevity research, brain health interventions, or the future of mitochondrial medicine, this conversation reveals where the science is headed next. 🌐Links in this video Time-Line home page https://www.timeline.com/ ATLAS Trial: Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults https://pubmed.ncbi.nlm.nih.gov/35584623/ Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial https://www.nature.com/articles/s43587-025-00996-x