Microplastics, Rapamycin, NAD, and Quantum Energy: Reactions to Day One of AGE2026

Subscribe to our channel: https://www.youtube.com/@mkaeberlein What happens when you leave a wellness-focused longevity conference in Berlin and fly straight into one of the world's premier scientific aging research meetings? In this special recap from Day 1 of the 2026 American Aging Association (AGE) Annual Meeting, I sit down with Dr. Kevin White to discuss the biggest themes emerging from the conference and what they tell us about the current state of the longevity field. One theme stood out above all others: rapamycin and mTOR biology continue to dominate the scientific conversation around aging. From immune function and inflammation to ovarian aging, brain health, and metabolism, the evidence supporting mTOR as a central regulator of aging appears stronger than ever. We also discuss the growing disconnect between evidence-based aging science and the broader wellness industry. While scientific meetings like AGE focus on rigorous basic, translational, and clinical research, much of the public conversation around longevity is increasingly driven by influencers, untested interventions, and marketing hype. Other topics include: New research on rapamycin and immune resilience Why mTOR remains one of the most important pathways in aging biology The decline of the NAD/sirtuin narrative and where the field is heading next Microplastics and what the science actually says about risk Gut microbiome research and healthy aging Circadian biology, sleep, and longevity The importance of clinical trials in longevity medicine Why scientists and clinicians need to work more closely together If you're interested in separating evidence-based longevity science from hype, this conversation provides an inside look at what leading researchers are actually discussing today. In This Episode 00:00 Introduction and conference overview 01:20 Science vs. wellness: two very different longevity worlds 05:40 Why biotech involvement at AGE is a positive sign 07:00 Rapamycin, mTOR, and immune aging 11:00 Is the field moving away from NAD and sirtuins? 14:00 Microplastics: what should we really worry about? 17:00 Gut microbiome, metabolism, and circadian biology 18:30 Why sleep may be more important than you think Subscribe for evidence-based discussions on aging biology, longevity medicine, and the science of healthy aging. #Longevity #Aging #Rapamycin #mTOR #HealthyAging #Microplastics #NAD #Sleep #CircadianRhythm #LongevityScience #Healthspan #AgingResearch DISCLAIMER: The information provided on this channel is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find me: Instagram: https://www.instagram.com/mkaeberlein/ LinkedIn: https://www.linkedin.com/in/mkaeberlein/ Twitter: https://twitter.com/mkaeberlein Facebook: https://www.facebook.com/matt.kaeberlein/ --- Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this channel I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!