From Paper to Plate Ep. 1 — How Food Controls Cellular Aging

What if your food could talk to your cells? 🧬 In Episode 1, we break down how nutrient sensing (mTOR, insulin/IGF-1, sirtuins) controls aging — and what it means in your kitchen.👇 Watch now + grab the Longevity Reset Soup recipe! 🧠 EPISODE OVERVIEW Nutrient sensing pathways (mTOR, insulin/IGF-1, sirtuins) The growth vs. longevity trade-off Longevity Reset Soup recipe Fasting Mimicking Diet (FMD) explained 🔬 RESEARCH PAPERS López-Otín et al. (2013) The Hallmarks of Aging —https://pmc.ncbi.nlm.nih.gov/articles/PMC3836174/ López-Otín et al. (2023) Hallmarks of Aging: An Expanding Universe — https://www.sciencedirect.com/science/article/pii/S0092867422013770 Fontana & Partridge (2015) Promoting Health and Longevity Through Diet — https://www.sciencedirect.com/science/article/pii/S0092867415001865 If link doesn’t open, search the paper title through several links — free versions often exist. 🕒 TIMESTAMPS 0:00 Intro & Series Overview 1:20 Paper #1: The Hallmarks of Aging 5:00 The 12 Hallmarks Explained 7:00 Nutrient Sensing 7:30 Insulin/IGF-1: The Energy Sensor 7:50 mTOR: The Protein Sensor 8:50 Sirtuins: The Scarcity Sensor13:00 Growth vs. Longevity 15:30 Paper #2: Promoting Health and Longevity Through Diet 16:30 What matters about diet 17:15 Dietary restriction 19:00 Time restricted feeding 20:30 Portein restriction 22:20 Gut microbiome 30:00 FMD Diet 32:30 Longevity Reset Soup 53:45 Wrap-Up 📋 RESOURCES 📄 Download: Longevity Reset Soup + 5-Day FMD Plan (PDF): https://drive.google.com/file/d/1cDfPB2hoMbI8OH7bRqjs7Q6-IozgwIvL/view?usp=sharing 🧪 ProLon FMD System (recommended for first-timers): https://amzn.to/47e1Y8Z 📘 Valter Longo – The Longevity Diet: https://amzn.to/47e1Y8Z ⚖️ Kitchen Scale: https://amzn.to/4oFo0qW 🎥 My 5-Day FMD Video: https://youtu.be/1rs0uEWo4co 📖 Better Broths and Healing Tonics (for a veggie broth recipe): https://amzn.to/48Pd45x ⚠️ DISCLAIMER The 5-Day FMD protocol isn’t right for everyone. Avoid if underweight, pregnant, breastfeeding, have an eating disorder history, or certain medical conditions. Always consult your doctor before starting. Educational content only — not medical advice. 🗺️ SERIES ROADMAP Ep. 2 → Mitochondrial Power Plants (11/26)Ep. 3 → Disabled MacroautophagyEp. 4 → Chronic InflammationEp. 5 → Loss of Proteostasis…and more through all 12 Hallmarks of Aging. 💬 JOIN THE CONVERSATION Which nutrient-sensing pathway surprised you most? Drop your thoughts below 👇 📸 Instagram: @JulieGibsonClark - for longevity terms defined (or sign up for my email over at www.juliegibsonclark.com) 🎓 ABOUT THIS SERIES I’m not a scientist (I failed chemistry twice 😅). However, I did beat some billionaires spending under $150 a month on biohacking: https://youtu.be/kxYI20JV3O8?si=dfnyHkFp8EnJqbyw I’m creating my own “degree” in longevity science — reading research papers and translating them into simple, practical kitchen strategies. Every episode = 1–2 papers · Plain English · Real food applications. 🔔 NEXT EPISODE: COMING 11/26 Ep. 2 – Mitochondrial Power PlantsPapers: Andreux et al. (2019) Urolithin A & Mitophagy — Nature Metabolism Palikaras et al. (2015) Mitophagy & Age-Related Pathologies — Cell Death & Differentiation 🧬 From Paper to Plate 🫀 Juls