Translational Geroscience: Can rapamycin extend healthy longevity in humans? -Adam R. Konopka, PhD

In this presentation, Adam R. Konopka, PhD, Assistant Professor of Medicine in the Division of Geriatrics & Gerontology at UW–Madison, explores the exciting field of translational geroscience and investigates a key question: Can rapamycin extend healthy longevity in humans? Dr. Konopka reviews his team’s ongoing human clinical trials at UW–Madison that are examining whether rapamycin—a well-studied, FDA-approved drug—can safely support aspects of healthy aging. He introduces the foundational concepts of geroscience, provides background on rapamycin, and highlights compelling research showing its ability to extend lifespan and delay age-related conditions in multiple animal models. The talk concludes with the scientific rationale and research approach behind translating these animal findings to humans, offering valuable insight into one of the most promising areas of longevity research. To view subtitles or Closed Captions, click the CC button.