Can Spermidine Boost Muscle Repair in Older Adults? | Søren Wilton Kudahl-Laursen

🔬 Explore Pure Spermidine: https://donotage.org/pure-spermidine As we age, our muscles lose more than size. They also lose some of their ability to repair themselves. Could spermidine help? At the DoNotAge Conference 2026 in London, Søren Wilton Kudahl-Laursen of Aarhus University, Denmark, shares how his team is testing that question in a new human clinical trial using DoNotAge.org Pure Spermidine. In this talk he covers: Why skeletal muscle matters for movement, balance and metabolic health Sarcopenia, and how muscle quality changes with age Muscle stem cells, the body’s own repair crew, and why they slow down as we get older Early research linking spermidine and autophagy to better muscle stem cell function A new trial in adults aged 65 and over, testing 40 mg of DoNotAge.org Pure Spermidine a day against a placebo PolyCAD, a separate Aarhus trial of DoNotAge.org Pure Spermidine in 180 people with heart disease, with results expected soon The session closes with a plain-English summary from DoNotAge.org founder Alan Graves. Chapters 0:00 Introduction 0:16 Does spermidine improve muscle stem cell function? 1:02 Why skeletal muscle matters 1:48 Sarcopenia and age-related muscle loss 3:06 Muscle regeneration and stem cells 5:16 How ageing affects muscle stem cells 6:18 Spermidine and autophagy 9:32 The new clinical trial in older adults 11:18 How the muscle injury model works 12:50 What the trial will measure 14:52 The PolyCAD heart trial 17:24 The research team 18:10 Session summary with Alan Graves DoNotAge.org is a Health Research Organisation on a mission to extend the healthy lifespan of as many people as possible. #Spermidine #HealthyAgeing #Longevity