The Anti-Aging Supplement Scam (New Evidence)
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Creator description Β· original textText language: English
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Timestamps:
00:00 The Interventions Testing Program
03:41 The Breakthrough: Rapamycin
05:21 The Excitement Around Astaxanthin and AKG
09:44 The ITP's Latest Results
11:16 Conclusion and Key Takeaways
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Here are the links to the research papers referenced in the video:
Astaxanthin/meclizine ITP 2023 β https://link.springer.com/article/10.1007/s11357-023-01011-0
Rejuvant "longevity escape velocity" press release β https://www.globenewswire.com/news-release/2023/03/28/2635803/0/en/67-Year-Old-Founder-of-Ponce-De-Leon-Health-Achieves-Longevity-Escape-Velocity-with-Rejuvant.html
ITP 2026 paper (all 11 compounds fail) β https://link.springer.com/article/10.1007/s11357-026-02201-2
NIA ITP overview β https://www.nia.nih.gov/research/dab/interventions-testing-program-itp
NIA ITP about page (UM-HET3 mice) β https://www.nia.nih.gov/research/dab/interventions-testing-program-itp/about-itp
NR extends lifespan in mice (Zhang 2016) β https://www.science.org/doi/10.1126/science.aaf2693
NR fails ITP (17-a-estradiol paper) β https://pmc.ncbi.nlm.nih.gov/articles/PMC8135004/
Rapamycin discovery (Easter Island) β https://pmc.ncbi.nlm.nih.gov/articles/PMC9494524/
Rapamycin extends lifespan (Harrison 2009, Nature) β https://www.nature.com/articles/nature08221
Science top 10 breakthroughs 2009 β https://www.science.org/doi/10.1126/science.326.5960.1600
ITP supported interventions list β https://www.nia.nih.gov/research/dab/interventions-testing-program-itp/supported-interventions
AKG extends lifespan (Buck Institute 2020) β https://pmc.ncbi.nlm.nih.gov/articles/PMC8508957/
Lithgow quote (Buck press release) β https://www.buckinstitute.org/news/a-metabolite-produced-by-the-body-increases-lifespan-and-dramatically-compresses-late-life-morbidity-in-mice/
Sinclair AKG tweet β https://x.com/davidasinclair/status/1300868036023459841
Rejuvant "8 year" study (Demidenko 2021) β https://www.aging-us.com/article/203736/text
Horvath clock comparison β https://www.mdpi.com/2673-8856/5/2/28
Resveratrol in mice (Sinclair 2006, Nature) β https://www.nature.com/articles/nature05354
GSK acquires Sirtris for $720M β https://www.fiercebiotech.com/biotech/glaxosmithkline-gsk-to-acquire-sirtris-pharmaceuticals-a-world-leader-sirtuin-research-and
Resveratrol not a direct SIRT1 activator β https://pmc.ncbi.nlm.nih.gov/articles/PMC2832984
SRT501 trial halted (kidney damage) β https://www.fiercebiotech.com/biotech/safety-concerns-force-glaxo-to-suspend-enrollment-srt501-trial
GSK shuts down Sirtris β https://www.bioworld.com/articles/438084
Kaeberlein "most debunked" quote β https://www.levels.com/blog/matt-kaeberlein-longevity-science
Astaxanthin skin meta-analysis β https://pmc.ncbi.nlm.nih.gov/articles/PMC8472736/
Thumbnail by James Kelly
Video edited by Troy Young
Script by John Milliken
The content contained in this video, and its accompanying description, is not intended to replace viewersβ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.
Dr Brad Stanfield Β· 13 min Β· Source published: 2026-04-07
Added to Harbor: 10/23/2026
Original on YouTube βAutomatically categorized source. Creator statements are not an independent evidence review or personal medical guidance.