David Sinclair's $720 Million Anti-Aging Flop (What NMN Fans Should Know, Part 3)

David Sinclair co-founded Sirtris, the anti-aging company GSK bought for about 720 million dollars, and it flopped. Here is that honest story and what it means for NAD and NMN fans today. Part 3 is the cautionary tale every longevity fan should know before spending a cent. Resveratrol, the red wine molecule, had an even bigger story than NMN: it was said to switch on your longevity enzymes, a pharma giant paid around 720 million dollars for it, and then careful science found the headline effect was largely an artifact of how it was measured. By 2013 the whole effort was quietly shut down. It is almost exactly the template NAD boosters follow today. The good news: the most proven ways to raise your own NAD are free. Part 3, the finale of the NAD longevity series. Chapters: 0:00 The cautionary tale 0:19 Resveratrol, the red wine miracle 1:04 The $720 million bet 1:39 When the careful science arrived 2:31 The 2013 shutdown 2:58 The same template as NMN today 3:29 The free ways to raise your NAD 3:44 Exercise 4:10 Eating, sleep and daily rhythm 4:36 The drains: alcohol and sun 5:09 The punchline and honest close IMPORTANT, PLEASE READ. This video is educational only. It is not medical advice, and nothing here is a recommendation to take, buy, or avoid any supplement. NMN and NR are sold as dietary supplements; the anti-aging claims on the label are not proven in humans. Always talk to a qualified doctor before starting anything. What we cover: The resveratrol hype and the roughly 720 million dollar Sirtris deal Why the headline sirtuin result was largely a measurement artifact How the human trials disappointed, and the 2013 shutdown Why this is the template NMN and NR are following now The free, proven ways to raise and protect your own NAD Free guide: tinyurl.com/SecondOpinionGuide Smart ideas are shared by smart people. If this whole series helped, follow and share. Sources: GSK's acquisition of Sirtris (about 720 million dollars, 2008) and its 2013 wind-down; the sirtuin fluorophore assay-artifact critique (Pfizer and others); disappointing human resveratrol trials; exercise, fasting, circadian and NAD-consuming-pathway literature on raising and preserving NAD. This channel cites primary research. #resveratrol #nmn #longevity