Longevity supplements promise to reverse aging—what the trials really show

Longevity supplements promise to reverse aging—what the trials really show. NAD+ levels naturally fall as we age, and a January 2026 study proved that NMN and NR can double circulating NAD+ in just two weeks. That part is solid. But no human trial has ever demonstrated these compounds extend lifespan, and the longest study lasted only twelve weeks. Senolytics such as dasatinib + quercetin or fisetin aim to clear senescent cells, yet human data remain tiny pilot studies. Meanwhile, basics like vitamin D, omega‑3, magnesium, and adequate protein are backed by decades of human research. Red flags: “reverse” without specifying what, mouse data presented as human proof, and testimonial‑driven claims. Would you spend on an unproven anti‑aging pill or stick to evidence‑based basics? Share your thoughts in the comments or tag someone who’s considering these supplements.