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Video library· TimePie

Hongbing Zhang: Targeting Mechanistic Target of Rapamycin (mTOR) in Precision Medicine

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Dr. Hongbing Zhang talked about the clinical applications of mTOR and rapamycin at the 5th Timepie Longevity Forum. Dr. Hongbing Zhang is a distinguished scientist with a notable academic and research career. He earned the Outstanding Dissertation Award from the Perelman School of Medicine at the University of Pennsylvania and completed his postdoctoral training at the National Institutes of Health (NIH) and Harvard Medical School, where he also served as a lecturer. Currently, he is a tenured professor at the Chinese Academy of Medical Sciences & Peking Union Medical College, a Distinguished Professor of the China Medical Board, a recipient of the National Science Fund for Distinguished Young Scholars, and a member of the State Key Laboratory of Common Mechanisms for Major Diseases. From 2014 to 2023, he has been recognized as one of China's Highly Cited Researchers and is currently ranked among the World's Top 2% Scientists. His research primarily focuses on the dysregulation of the mTOR signaling pathway and its role in the onset, diagnosis, and treatment of diseases such as cancer. His work encompasses a wide range of conditions from rare diseases, such as hereditary breast cancer and tuberous sclerosis complex, to common cancers like liver, pancreatic, and lung cancer. By simulating human gene mutations in animal models and constructing disease models, Dr. Zhang explores the mechanisms underlying tumor development and other diseases, aiming to identify effective therapeutic strategies. His research efforts have led to the advancement of clinical trials and provided a foundation for the translation of basic medical research into clinical practice, promoting precision medicine. Notably, his work has made significant strides in making tuberous sclerosis complex and similar conditions preventable and treatable, thus alleviating the lack of medical care and treatments for some patients. #mTOR #rapamycin Timepie Longevity Forum is China's premier longevity innovation summit, focuses on longevity popularization and healthy life extension, and brings together the world's best minds decoding aging mechanisms and seeking anti-aging intervention measures. Find out more about Timepie Longevity Forum: https://www.timepielongevityforum.com/ Follow TimePie on: X -- https://x.com/TimePieChina Linkedin -- https://www.linkedin.com/company/timepie/

TimePie · 40 min · Source published: 2025-07-10

Added to Harbor: 10/22/2026

Original on YouTube ↗

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