Podcast with Dr. Nir Barzilai on biological age, longevity genes and aging drugs
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Automatic summary · not editorially reviewedIn this podcast description, Dr. Nir Barzilai discusses genetic factors in people over 100, growth hormone and IGF-1, drugs such as metformin, GLP-1 and SGLT2 inhibitors, peptides, biological age tests and the evidence level of hyperbaric oxygen and stem cell treatments. [1]
Dr. Barzilai researches protective genes that delay aging and age-related diseases in people over 100. [1]
The description names metformin, GLP-1 and SGLT2 inhibitors as drugs with longevity potential. [1]
The episode is said to discuss the evidence levels of hyperbaric oxygen and stem cell treatments. [1]
Barzilai's research on people over 100
According to the description, Dr. Nir Barzilai is Professor of Medicine and Genetics at Albert Einstein College of Medicine and Director of the Geroscience Institute. He studies protective genes that delay aging and age-related diseases in people over 100. The description says his research shows that healthy, long life cannot be explained by nutrition, exercise and supplements alone, and it asks how some people pass 100 despite not following healthy-living rules. [1]
Hormones, drugs and peptides discussed
The description lists growth hormone and IGF-1 and their effects that change with age, and why hormone effects shift after age 50. It names metformin, GLP-1 and SGLT2 inhibitors as drugs with longevity potential, and says the risks of the peptides MOTS-c and Humanin and unnecessary supplement use are covered. Barzilai is described as a pioneer of the TAME study, which examines metformin's effect on aging. [1]
Biological age tests and treatment evidence
The description says the episode covers the future of biological age tests, the evidence levels of hyperbaric oxygen and stem cell treatments, and why aging biology rather than individual diseases should be targeted. It also lists longevity clinics, rapamycin, the question whether a 120-year human lifespan is possible, Barzilai's own longevity routine and intermittent fasting. The stated goal is not only longer life but staying healthy until the end of life. [1]
Context & limits
This is only the video description; the video and transcript were not reviewed. The description announces topics and questions but reports no study design, sample, follow-up, results or effect sizes. Statements about longevity potential and evidence levels are attributed to the description and are not established here.
Based on the creator’s description; the full video and transcript were not analyzed.
Quoted passages in the original language
Yüz yaşını aşan kişilerde yaşlanmayı ve yaşa
metformin, GLP-1 ve SGLT2 inhibitörleri gibi ilaçların
hiperbarik oksijen ve kök hücre tedavilerinin kanıt
About this video
Creator description · original textText language: Turkish
Ayık Kafa · 63 min · Source published: 2026-10-16
Added to Harbor: 10/23/2026
Original on YouTube ↗Automatically categorized source. Creator statements are not an independent evidence review or personal medical guidance.