Top 7 ways to reverse aging and outlive Bryan Johnson

Linked playlists and videos: https://www.youtube.com/playlist?list=PLXoKcD0kKb9a3-1lEbfZtMlk0ztARQj5x https://www.youtube.com/playlist?list=PLXoKcD0kKb9a5Yekwx9Xu_Sf8yreQuIPd https://youtu.be/oXHJlukGSw4 https://youtu.be/3c5rWOBqXPE https://youtu.be/Q2XvKn0Uq1Q https://youtu.be/e1A7px7lt9k https://youtu.be/KNmUlbaI5_k https://youtu.be/l5Y1OHiBm2c https://youtu.be/mKPg5tFxd64 Sources (partial, rest in comment): 1. 161385360554578. Common pill taken by millions could “slash risk of dementia and dying young.” The Sun. August 7, 2025. Accessed August 10, 2025. https://www.thesun.co.uk/health/36190130/common-pill-metformin-diabetes-slash-risk-dementia-dying/ 2. Bannister CA, Holden SE, Jenkins-Jones S, et al. Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls. Diabetes Obes Metab. 2014;16(11):1165-1173. doi:10.1111/dom.12354 3. Barzilai DA. Mikhail ‘Misha’ Blagosklonny’s enduring legacy in geroscience: the hyperfunction theory and the therapeutic potential of rapamycin. Aging. 2025;17(1):1-15. doi:10.18632/aging.206189 4. Bitto A, Ito TK, Pineda VV, et al. Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice. eLife. 5:e16351. doi:10.7554/eLife.16351 5. Brandhorst S, Choi IY, Wei M, et al. A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance and healthspan. Cell Metab. 2015;22(1):86-99. doi:10.1016/j.cmet.2015.05.012 6. Cheng FF, Liu YL, Du J, Lin JT. Metformin’s Mechanisms in Attenuating Hallmarks of Aging and Age-Related Disease. Aging Dis. 2022;13(4):970-986. doi:10.14336/AD.2021.1213 7. D’Onofrio G, Kirschner J, Prather H, Goldman D, Rozanski A. Musculoskeletal exercise: Its role in promoting health and longevity. Prog Cardiovasc Dis. 2023;77:25-36. doi:10.1016/j.pcad.2023.02.006 8. de Cabo R, Mattson MP. Effects of Intermittent Fasting on Health, Aging, and Disease. Longo DL, ed. N Engl J Med. 2019;381(26):2541-2551. doi:10.1056/NEJMra1905136 9. Ding D, Nguyen B, Nau T, et al. Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis. The Lancet Public Health. 2025;10(8):e668-e681. doi:10.1016/S2468-2667(25)00164-1 10. Ehninger D, Neff F, Xie K. Longevity, aging and rapamycin. Cell Mol Life Sci. 2014;71(22):4325-4346. doi:10.1007/s00018-014-1677-1 11. Ference BA, Ginsberg HN, Graham I, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. European Heart Journal. 2017;38(32):2459-2472. doi:10.1093/eurheartj/ehx144 12. Forni MF, Peloggia J, Braga TT, et al. Caloric Restriction Promotes Structural and Metabolic Changes in the Skin. Cell Reports. 2017;20(11):2678-2692. doi:10.1016/j.celrep.2017.08.052 13. Gremeaux V, Gayda M, Lepers R, Sosner P, Juneau M, Nigam A. Exercise and longevity. Maturitas. 2012;73(4):312-317. doi:10.1016/j.maturitas.2012.09.012 14. Harrison DE, Strong R, Sharp ZD, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009;460(7253):392-395. doi:10.1038/nature08221 15. Harrison DE, Strong R, Sharp ZD, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009;460(7253):392-395. doi:10.1038/nature08221 16. Hughes MCB, Williams GM, Baker P, Green AC. Sunscreen and prevention of skin aging: a randomized trial. Ann Intern Med. 2013;158(11):781-790. doi:10.7326/0003-4819-158-11-201306040-00002 17. Jean-Louis G, Grandner MA, Pandi-Perumal SR. Sleep Health and Longevity—Considerations for Personalizing Existing Recommendations. JAMA Netw Open. 2021;4(9):e2124387. doi:10.1001/jamanetworkopen.2021.24387 18. Kaeberlein M. Rapamycin and aging: When, for how long, and how much? J Genet Genomics. 2014;41(9):459-463. doi:10.1016/j.jgg.2014.06.009 19. Kargin D, Tomaino L, Serra-Majem L. Experimental Outcomes of the Mediterranean Diet: Lessons Learned from the Predimed Randomized Controlled Trial. Nutrients. 2019;11(12):2991. doi:10.3390/nu11122991 20. Kawanishi K, Dhar C, Do R, Varki N, Gordts PLSM, Varki A. Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms. Proceedings of the National Academy of Sciences. 2019;116(32):16036-16045. doi:10.1073/pnas.1902902116 :