Age of a single cell! (epigenetic clocks)
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Creator description · original language
There are many different biomarkers that have now been used to develop so-called aging clocks that predict biological or chronological age. But one biomarker that has seen the most advances so far are epigenetic clocks that use DNA methylation as a measurement.
Currently, these tools work by using "bulk" data however this misses acquisition of heterogeneity in a dataset. But, a new publication in Nature Aging has now developed a framework for predicting age of a single cell! In this video we discuss how.
P.S I interviewed the lead author of the paper - you can view here - https://youtu.be/5LcgovlTxIM
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TIMESTAMPS:
Intro - 00:00
Epigenetic clocks - 00:50
Age of a single cell - 03:00
Applications of single cell age - 08:15
References:
Trapp, A., Kerepesi, C. & Gladyshev, V.N. Profiling epigenetic age in single cells. Nat Aging 1, 1189–1201 (2021). https://doi.org/10.1038/s43587-021-00134-3
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The Sheekey Science Show · 11 min · Source published: 2022-01-19
Added to Harbor: 10/22/2026
Original on YouTube ↗Automatically categorized source. Creator statements are not an independent evidence review or personal medical guidance.