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Video library· DoNotAgeAudio language not provided

Talk on a crowdfunded replication of a 2020 young-plasma rat ageing claim

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At a glance

Automatic summary · not editorially reviewed

The description says Nicolás Cherñavsky tells how he and his wife tried to independently check a 2020 claim that old rats were made biologically younger with tiny particles from young pig plasma; the first replication attempt did not show rejuvenation, and further mouse and rat experiments would come before any human use. [1]

  1. The description says a 2020 study claimed old rats were made biologically younger using tiny particles from young pig plasma, with epigenetic clock analysis by Steve Horvath. [1]

  2. According to the description, the first crowdfunded replication attempt did not show rejuvenation, and something was missing from the original paper. [1]

  3. The description mentions next experiments in mice and rats and what would need to happen before any human use. [1]

Cherñavsky recounts the 2020 rat claim

According to the description, a 2020 study claimed that old rats had been made biologically younger using tiny particles taken from young pig plasma. The description attributes the study to Harold Katcher, with epigenetic clock analysis by Steve Horvath, and says it claimed a dramatic reversal of biological age in rats. Cherñavsky, co-founder of the Rejuvenation Science Institute in Brazil, presents this story at the DoNotAge Conference 2026 in London. The description does not report the study's sample size, design details or measured outcomes beyond the claim itself. [1]

First replication attempt showed no rejuvenation

The description says Cherñavsky and his wife set out to check the claim independently, and that patents and secrecy slowed the research, which led them to found a non-profit institute to publish everything openly. It describes a crowdfunded replication study, with DoNotAge.org giving the first major donation. According to the description, the first attempt did not show rejuvenation, and something was missing from the original paper. The description does not specify what was missing or how the replication was designed. [1]

Next mouse and rat work before any human use

The description lists next experiments in mice and rats and says what would need to happen before any human use, including safety testing and next steps. It does not report results from those experiments or a timeline. The session closes with a short summary from DoNotAge.org founder Alan Graves. The description frames the work as ongoing preclinical research; it gives no evidence of benefit in humans and no safety conclusion for human use. [1]

Context & limits

This is based only on the video description; the video and transcript were not reviewed. The description gives no sample sizes, study designs, measured outcomes or replication details, and reports no human data.

Based on the creator’s description; the full video and transcript were not analyzed.

[1] Could Young Blood Reverse Ageing? | Nicolás Cherñavsky
Quoted passages in the original language
tiny particles taken from young pig plasma
the first attempt didn’t show rejuvenation
before any human use

About this video

Creator description · original textText language: English

In 2020, a study claimed that old rats had been made biologically younger using tiny particles taken from young pig plasma. Can the results be replicated? At the DoNotAge Conference 2026 in London, Nicolás Cherñavsky, co-founder of the Rejuvenation Science Institute in Brazil, shares the story of trying to find out. Nicolas covers: The 2020 study by Harold Katcher, with epigenetic clock analysis by Steve Horvath, that claimed a dramatic reversal of biological age in rats Why he and his wife, set out to check the claim independently How patents and secrecy slowed the research, and why they founded a non-profit institute to publish everything openly The crowdfunded replication study, where DoNotAge.org gave the first major donation Why the first attempt didn’t show rejuvenation, and what was missing from the original paper The next experiments in mice and rats, and what would need to happen before any human use The session closes with a short summary from DoNotAge.org founder Alan Graves. Chapters 0:00 Was rejuvenation invented in 2020? 1:34 Checking an extraordinary claim 3:22 Asking Steve Horvath and Aubrey de Grey 5:36 Harold Katcher and the young plasma experiment 7:36 How patents slowed progress 10:06 Founding the Rejuvenation Science Institute 11:52 Crowdfunding the replication study 13:22 The first results 14:24 What the original paper left out 15:00 Next experiments in mice and rats 17:00 Safety testing and next steps 18:52 Why this work matters 19:52 Session summary with Alan Graves Learn more about the Rejuvenation Science Institute: rejuvenescimento.org DoNotAge.org is a Health Research Organisation on a mission to extend the healthy lifespan of as many people as possible. #Longevity #Rejuvenation #AgeingResearch

DoNotAge · 21 min · Source published: 2026-10-20

Added to Harbor: 10/23/2026

Original on YouTube ↗

Automatically categorized source. Creator statements are not an independent evidence review or personal medical guidance.

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