Episode 10: Blue Zones Blueprint: India-Singapore Aging Breakthroughs | Brian Kennedy

In this episode, Mr. Prashant Prakash and Prof. Deepak Saini are joined by Prof. Brian Kennedy, and the conversation spans the science and systems shaping healthy longevity today — from second-generation aging clocks, biomarkers, peptides, stem cells, and omics-driven personalization, to what these advances mean for India’s biologically and culturally diverse population. Prof. Kennedy also shares insights from Singapore’s ABIOS biobank (400+ participants), India’s ambition to build 5,000+ profiles, and why collaboration between Bengaluru and Singapore could be critical for the future of longevity science. Beyond biology, the episode unpacks Singapore’s “blue zone–like” success through urban design, green spaces, and active living, and traces Prof. Kennedy’s journey from foundational discoveries in yeast to human health-span trials. The discussion also examines evidence-backed interventions such as spermidine, AKG, Ashwagandha, and Brahmi, alongside emerging questions around NAD+, AI, and aging clocks. Timestamps 00:00 – Introduction 01:50 – Introduction to Prof. Brian Kennedy 02:42 – Singapore as a “Blue Zone” 05:00 – Diet and health shifts 05:50 – Longevity impact 06:10 – Research and trials 08:55 – India and aging research 11:10 – ABIOS and the BHARAT study 13:00 – AI in longevity science 17:20 – Biomarkers and omics 19:10 – Vitamins, supplements, and interventions 22:45 – Spermidine 24:25 – Ayurveda 28:10 – NAD+, AKG, and indicators 31:45 – Aging clocks 34:25 – Key biological pathways Prof. Kennedy is a Director of the Healthy Longevity Translational Research Programme at the Luan School of Medicine, National University of Singapore. He unpacks Singapore’s “blue zone” success through urban design, green spaces, and active living, and the episode traces Prof. Kennedy’s journey from foundational discoveries in yeast to human health-span trials. The discussion also examines interventions such as spermidine, AKG, Ashwagandha, and Brahmi, alongside emerging questions around NAD+, AI, and aging clocks. About Biopeak: Biopeak is a deep science-led longevity organization focused on personalized, precise, predictive, and preventive healthcare. Built for South Asia, our approach blends cutting-edge diagnostics with systems science to craft personalised health plans. Biopeak helps you not just live longer—but live without limits. Biopeak. Decode your path to Limitless Living. Follow Us: Longevity India: https://www.longevity.iisc.ac.in/ Biopeak: https://biopeak.com/ LinkedIn: https://www.linkedin.com/company/longevity-india-iisc/ Instagram: https://www.instagram.com/longevity_iisc/ Spotify: https://open.spotify.com/show/0NXTdG0fBIfmKIHV2vkxbV Disclaimers: The content shared on the Biopeak Live podcast is intended for general educational purposes only and should not be considered as medical advice. We strongly recommend consulting a licensed healthcare professional for any health-related concerns, especially before making any lifestyle, dietary, or medical changes based on the content provided in this podcast. References: https://www.youtube.com/watch?v=5KvXrVmYWlY Biomarkers of aging for the identification and evaluation of longevity interventions Validation of biomarkers of aging Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity Hallmarks of female reproductive aging in physiologic aging mice