What are senolytics (and should you be taking them)?

These compounds are said to fight aging by clearing “zombie cells” out of your body. Is there any science to back this up? References Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial - PubMed (https://pubmed.ncbi.nlm.nih.gov/38956196/) A pilot study of senolytics to improve cognition and mobility in older adults at risk for Alzheimer’s disease - ScienceDirect (https://www.sciencedirect.com/science/article/pii/S2352396425000568) JCI - Strategies targeting cellular senescence (https://www.jci.org/articles/view/95149) Targeting senescent cells: approaches, opportunities, challenges - PMC (https://pmc.ncbi.nlm.nih.gov/articles/PMC6949083/) Targeting cellular senescence with senotherapeutics: senolytics and senomorphics - Zhang - 2023 - The FEBS Journal - Wiley Online Library (https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16350) New to Nutrition Diva? Check out our special Spotify playlist (https://open.spotify.com/playlist/59vwhJqu3bTvSCRsXmbqY6) for a collection of the best episodes curated by our team and Monica herself!  We've also curated some great playlists on specific episode topics including Staying Strong as We Age (https://open.spotify.com/playlist/1w4QoYhyNeiNXmG8i36n5r?si=fEPfi3EyR8SpTSGrOMCsWw) , Diabetes (https://open.spotify.com/playlist/4ElNfNcs5JNgFEKA9TCW1d) , Weight Loss That Lasts (https://open.spotify.com/playlist/5qNro1QNdnjz8BIUq8DA44?si=Wx4vacCtTzWFsCmYsJqQrg&nd=1&dlsi=cc716db299654817) and Gut Health (https://open.spotify.com/playlist/72UY4cxujSxcOcRiPflsyi) ! Also, find a playlist of our bone health series, Stronger Bones at Every Age (https://open.spotify.com/playlist/40l1EDvXS55Ar1YdN0dolA?si=nw7KfroLQq2LUqlkYydlkA) .  Have a nutrition question? Send an email to nutrition@quickanddirtytips.com. Follow Nutrition Diva on Facebook (https://facebook.com/qdtnutrition) and subscribe to the newsletter (https://www.quickanddirtytips.com/nutrition-diva-newsletter) for more diet and nutrition tips.  Find out about Monica's keynotes and other programs at WellnessWorksHere.com (https://wellnessworkshere.com) Nutrition Diva is a part of the Quick and Dirty Tips (https://quickanddirtytips.com) podcast network.