Brad Stanfield on Rapamycin Longevity Series | Rapamycin, mTOR and the importance of muscle in life

Dr Brad Stanfield works as a medical doctor in New Zealand and beside his work in primary-care he has his own Youtube channel, in which he goes through the latest research and clinical guidelines on preventative medicine and longevity. In today’s podcast we are going to talk about Brad’s upcoming Rapamycin trial, the importance of muscle when we get older, sarcopenia and lots of other interesting longevity topics. 00:00 Intro 01:45 Common health problems in the clinic 04:01 When does muscle decline start? 05:09 How to minimize muscle decline 08:47 Low protein or high protein diet? 11:44 Animal or plant based protein? 14:08 Methionine restriction 15:23 Why Brad started his Rapamycin trial 16:04 Rapamycin and human research 17:35 Rapamycin, mTOR and muscle building 19:15 The Rapamycin trial design 21:21 Rapamycin blunts the effects of exercise? 22:28 Dose regime in the Rapamycin trial 23:56 Difference between the PEARL trial 24:39 Status of Brad's Rapamycin trial 26:38 Trial donation possibilities 29:13 Navigate better among all health claims 32:01 The evidence pyramid 34:36 Benefits of randomized controlled trials 39:38 Why Brad started his Youtube channel 40:51 Brad's supplement stack 48:25 The compound Taurine 50:05 Verify supplement quality and purity 51:09 Brad's view on Rapamycin 53:23 Rapamycin risks 55:05 Definition of blunt of exercise 55:40 Metformin have blunting effects of exercise 56:48 Weak points around Rapamycin 58:03 How well will Rapamycin translate to humans 59:07 The most promising longevity interventions 1:02:00 Brad's longevity interventions 1:05:03 How combine longevity interventions 1:07:17 How to find the mTOR sweet spot 1:11:07 Brad's longevity intervention when he is old 1:12:24 How to keep updated in the longevity field 1:12:50 People Brad follows Links - Brad Stanfield's Youtube https://www.youtube.com/@DrBradStanfield - Donate to Brad's Rapamycin clinical trial https://drstanfield.com/pages/ongoing-clinical-studies - Brad's MicroVitamin supplement https://drstanfield.com/products/microvitamin - Brad's twitter https://twitter.com/BradStanfieldMD Rapamycin resources - Rapamycin Longevity Lab https://masteronething.com - Rapamycin.news https://www.rapamycin.news - Rapamycin Facebook group https://www.facebook.com/groups/rapamycin - Rapamycin Reddit group https://www.reddit.com/r/Rapamycin Connect with Krister on: Twitter: https://twitter.com/KristerKauppi Instagram: https://www.instagram.com/longevity.lifestyle.hacker Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.