Episode 7: Living by the Clock: How Time Shapes Your Health | Satchin Panda

In this episode, we’re joined by Dr. Satchidananda Panda, Professor at the Regulatory Biology Laboratory, Salk Institute, California, to dive into the fascinating science of the circadian rhythm and its powerful impact on our health. We explore the importance of circadian rhythm for the body’s daily functioning and how it works, along with the health risks that come from disrupting it, something common among shift workers, students, and new mothers. Dr. Panda also explains how hormones, light, and food influence our internal clock, and shares practical tips to reset and restore balance when our rhythm gets off track. He emphasizes why aligning with the circadian rhythm is key for lifestyle changes, better health, and long-term longevity. When your circadian rhythm is in sync, it boosts overall health, but when disrupted, it can raise the risk of chronic disease and poor health. Time stamp: 00:00- Introduction 01:41- Introduction to Dr. Satchin Panda 06:09- Fundamental functions of circadian clock 08:45- Circadian Clock gene 11:59- Hormonal regulation of circadian clock 14:55- Technology to measure circadian clock 19:01- Shift worker 26:35- Time restricted eating 31:07- Sleep and food timing 38:35- Effect on pathologies and life incidence 40:58- Night Owl 45:34- Entrepreneurship in the circadian rhythm space 50:24- Rapid fire questions #health, #longevity, #biologicalclock, #circadianrhythm, #stress, #sleep, #metabolism, #aging The Guest : Dr. Satchidananda (Satchin) Panda, is a Professor at the Salk Institute in California, where he conducts groundbreaking research on circadian rhythms and their impact on behaviour, physiology, and metabolism. He has been recognized with prestigious awards, including the Julie Martin Mid-Career Award in Aging Research and the Dana Foundation Award in Brain and Immune System Imaging. Discovered blue-light sensing cells in the retina which influence our circadian clock and related behaviours. His work has highlighted time-restricted feeding and its potential in preventing and reversing metabolic diseases. Connect with Dr. Satchidananda Panda: Panda Lab: https://panda.salk.edu Ontime Health: https://getontimehealth.com Reference: 1.Manoogian ENC, Zadourian A, Lo HC, Gutierrez NR, Shoghi A, Rosander A, Pazargadi A, Ormiston CK, Wang X, Sui J, Hou Z, Fleischer JG, Golshan S, Taub PR, Panda S. Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: The Healthy Heroes randomized control trial. Cell Metab. 2022 Oct 4;34(10):1442-1456.e7. doi: 10.1016/j.cmet.2022.08.018. PMID: 36198291; PMCID: PMC9536325. 2.Manoogian ENC, Panda S. Circadian rhythms, time-restricted feeding, and healthy aging. Ageing Res Rev. 2017 Oct;39:59-67. doi: 10.1016/j.arr.2016.12.006. Epub 2016 Dec 23. PMID: 28017879; PMCID: PMC5814245. 3.Longo VD, Panda S. Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan. Cell Metab. 2016 Jun 14;23(6):1048-1059. doi: 10.1016/j.cmet.2016.06.001. PMID: 27304506; PMCID: PMC5388543. 4.Panda S. Circadian physiology of metabolism. Science. 2016 Nov 25;354(6315):1008-1015. doi: 10.1126/science.aah4967. PMID: 27885007; PMCID: PMC7261592. Know more: The Circadian Code: https://www.penguinrandomhouse.com/books/592260/the-circadian-code-by-satchin-panda-phd/ About Biopeak : Biopeak is a deep science-led longevity organization focused on personalized, precise, predictive, and preventive healthcare. Built for South Asia, our approach blends cutting-edge diagnostics with systems science to craft personalised health plans. Biopeak helps you not just live longer—but live without limits. Biopeak. Decode your path to Limitless Living. Follow Us: Longevity India: https://www.longevity.iisc.ac.in/ Biopeak: https://www.biopeak.com/ LinkedIn: https://www.linkedin.com/company/longevity-india-iisc/ Instagram: https://www.instagram.com/longevity_iisc/ Spotify: https://open.spotify.com/show/0NXTdG0fBIfmKIHV2vkxbV