This Nasal Spray Destroys Inflammation

This week longevity researcher Ryker Black breaks the news on a new nasal spray that is set to redefine how we deal with systemic inflammation, or inflammaging as it's now commonly referred to. -------------- Exclusive DoNotAge 10% Discount Code: RYKER https://donotage.org/products This code will work for all DoNotAge products including subscriptions, special offers, and even the upcoming Black Friday sale. Enjoy! -------------- PEER REVIEWED STUDIES REFERENCED: Primary Studies (Cited in Script) 1. The 12 Hallmarks of Aging (2023) Full Citation: López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. "Hallmarks of aging: An expanding universe." Cell. 2023 Jan 19;186(2):243-278. Links: Publisher: https://www.cell.com/cell/fulltext/S0092-8674(22 )01377-0 PubMed: https://pubmed.ncbi.nlm.nih.gov/36599349/ Cited by: 4,688+ papers Relevance: This is THE definitive paper that officially added dysbiosis and chronic inflammation to the 12 Hallmarks of Aging in 2023. Essential foundation for the entire script. 2. Chronic Inflammation and the Hallmarks of Aging (2023 ) Full Citation: Baechle JJ, Chen N, Makhijani P, Winer S, Furman D, Winer DA. "Chronic inflammation and the hallmarks of aging." Molecular Metabolism. 2023 Aug;74:101755. Links: PubMed Central: https://pmc.ncbi.nlm.nih.gov/articles/PMC10359950/ Publisher: https://www.sciencedirect.com/science/article/pii/S2212877823000893 PubMed: https://pubmed.ncbi.nlm.nih.gov/37393021/ Cited by: 271+ papers 3. Maxwell Biosciences' Peptoid Antiviral Research (2023 ) Links: PubMed Central: https://pmc.ncbi.nlm.nih.gov/articles/PMC10425984/ Publisher: https://pubs.acs.org/doi/10.1021/acsinfecdis.3c00063 PubMed: https://pubmed.ncbi.nlm.nih.gov/37530426/ Cited by: 18+ papers Relevance: Maxwell Biosciences' own peer-reviewed research (Joshua McClure is a co-author ). Demonstrates how CLAROMER® peptoids target phosphatidylserine in pathogen membranes, providing the scientific basis for the "microscopic assassins" mechanism. Supporting Studies (Background Research) 4. Aging, Frailty, and the Microbiome: How Dysbiosis Influences Human Aging (2020) Links: PubMed Central: https://pmc.ncbi.nlm.nih.gov/articles/PMC7856216/ Cited by: 198+ papers 5. The Aging Gut Microbiome and Its Impact on Host Immunity (2021 ) Full Citation: Bosco N, Noti M. "The aging gut microbiome and its impact on host immunity." Genes & Immunity. 2021;22:289-303. Links: Publisher: https://www.nature.com/articles/s41435-021-00126-8 PubMed: https://pubmed.ncbi.nlm.nih.gov/33833439/ Cited by: 429+ papers 6. The Gut Microbiome as a Modulator of Healthy Ageing (2022 ) Full Citation: Ghosh TS, Rampelli S, Jeffery IB, et al. "The gut microbiome as a modulator of healthy ageing." Nature Reviews Gastroenterology & Hepatology. 2022;19:565-584. Links: Publisher: https://www.nature.com/articles/s41575-022-00605-x PubMed: https://pubmed.ncbi.nlm.nih.gov/35461002/ Cited by: 660+ papers 7. The Gut Microbiome, Aging, and Longevity: A Systematic Review (2020 ) Full Citation: Badal VD, Vaccariello ED, Murray ER, et al. "The Gut Microbiome, Aging, and Longevity: A Systematic Review." Nutrients. 2020 Dec;12(12):3759. Links: PubMed Central: https://pmc.ncbi.nlm.nih.gov/articles/PMC7762384/ Publisher: https://www.mdpi.com/2072-6643/12/12/3759 PubMed: https://pubmed.ncbi.nlm.nih.gov/33297486/ Cited by: 480+ papers 8. Inflammation and Aging: Signaling Pathways and Intervention Therapies (2023 ) Full Citation: Li X, Li C, Zhang W, et al. "Inflammation and aging: signaling pathways and intervention therapies." Signal Transduction and Targeted Therapy. 2023;8:239. Links: Publisher: https://www.nature.com/articles/s41392-023-01502-8 PubMed Central: https://pmc.ncbi.nlm.nih.gov/articles/PMC10267451/ PubMed: https://pubmed.ncbi.nlm.nih.gov/37291105/ Cited by: 990+ papers 9. Gut Dysbiosis: A Potential Link Between Increased Cancer Risk in Ageing and Inflammaging (2018 ) Full Citation: Biragyn A, Ferrucci L. "Gut dysbiosis: a potential link between increased cancer risk in ageing and inflammaging." The Lancet Oncology. Links: Publisher: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18 )30095-0/fulltext PubMed: https://pubmed.ncbi.nlm.nih.gov/29893270/ Cited by: 225+ papers Additional Maxwell Biosciences Research 10. Peptoids Against HSV-1 and SARS-CoV-2 (2021 ) Full Citation: Diamond G, Molchanova N, Herlan C, et al. "Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids." Pharmaceuticals (Basel). 2021 Apr 5;14(4):304. Links: PubMed Central: https://pmc.ncbi.nlm.nih.gov/articles/PMC8066196/ Publisher: https://www.mdpi.com/1424-8247/14/4/304 PubMed: https://pubmed.ncbi.nlm.nih.gov/33916450/ 11. Self-Assembly of Antimicrobial Peptoids on ESKAPE Pathogens (2022 ) Full Citation: Ryge TS, Frimodt-Møller N, Hansen PR. "New Strategies to Combat Bacterial Infections: Antimicrobial Peptides and Peptidomimetics." ACS Infectious Diseases. 2022. DOI: 10.1021/acsinfecdis.1c00629