EAPC statement proposes healthspan measures for physical activity research
This EAPC Scientific Statement notes that observational data link regular physical activity to lower all-cause mortality, but Mendelian randomization studies and randomized trials did not confirm this. It proposes healthspan measures as outcomes. [1]
Automatic summary · not editorially reviewed
The key findings
Observational data suggest regular physical activity lowers all-cause mortality, but Mendelian randomization studies and randomized controlled trials did not confirm this. [1]
The authors argue that limitations of observational data and controlled trials may compromise effects of exercise on mortality. [1]
The statement proposes physical function, mental and cognitive health, chronic disease prevention and quality of life as healthspan measures. [1]
The source at a glance
- Study type / format
- Scientific Statement (abstract)
- Population / context
- General populations addressed by the EAPC statement on physical activity and mortality
- Summary based on
- Study abstract
- Original publication
- September 1, 2026
Mortality link in observational data only
European Society of Cardiology prevention guidelines stress the benefits of exercise and an active lifestyle for cardiovascular risk reduction. Beyond that, observational data suggest regular physical activity lowers all-cause mortality. The statement says Mendelian randomization studies and randomized controlled trials did not confirm this.
Supporting source [1]
Proposed limits of observational and trial data
The authors argue that limitations of observational data, such as recall and recruitment bias, Hawthorne effects and possibly reverse causation, may distort effects of exercise on mortality. For controlled trials they name healthy volunteer bias and short follow-up. They add that modern medical care ensures longer survival despite high cardiovascular disease incidence, further reducing the potential impact of exercise on lifespan.
Supporting source [1]
Healthspan measures proposed as outcomes
The statement contrasts healthspan, life years in good health, with lifespan or mortality, which focus on longevity alone. It proposes healthspan measures to quantify effects of exercise and physical activity: physical function, mental and cognitive health, chronic disease prevention and quality of life. These could be assessed at population level with scalable, reliable, valid and non-invasive methods.
Supporting source [1]
How to interpret this
Abstract only; the full text was not reviewed. This is a Scientific Statement proposing a framework, not a validated or approved product. The proposed healthspan measures are suggestions, not tested outcomes.
Based on the study abstract; the full paper, tables and supplementary data were not reviewed.
Source & supporting passages
Bahls M, Kavousi M, Bakker EA, Kränkel N, Baurecht H, Timmermans EJ, van Craenenbroeck E, Hanssen H. · europepmc.org · September 1, 2026