Review: mitochondrial dysfunction in aged horses and links to human ageing research
This review synthesises current findings on mitochondrial dysfunction in aged horses, draws parallels with human medicine and identifies knowledge gaps; it proposes that combining human and equine research could support translational ageing models and better care of geriatric horses. [1]
Automatic summary · not editorially reviewed
The key findings
The review synthesises current findings on mitochondrial dysfunction in aged equines and draws parallels with human medicine. [1]
Integrating human and equine findings may offer new opportunities, including novel translational models for ageing research. [1]
The review highlights the need for mitochondrial research in aged horses to support prevention, treatment and management of geriatric horses. [1]
The source at a glance
- Study type / format
- Review (abstract)
- Population / context
- Aged equines (geriatric horses), with parallels drawn to ageing humans.
- Summary based on
- Study abstract
- Original publication
- May 11, 2026
Aged horses and mitochondrial dysfunction review
The source is a review of current findings on mitochondrial dysfunction in aged equines. It frames ageing as a complex biological process affecting a growing geriatric human and equine population worldwide, and describes mitochondrial dysfunction as one of the hallmarks of ageing and as a multifaceted process. The review draws parallels with human medicine.
Supporting source [1]
Proposed translational models and identified gaps
According to the abstract, integrating findings from human and equine research may bridge existing challenges and offer new opportunities, including the development of novel translational models for ageing research. The review also identifies current knowledge gaps and highlights the need for mitochondrial research in aged horses.
Supporting source [1]
Stated aims for geriatric horse care
The abstract states that such research is needed to enable accurate prevention strategies, treatment plans and management of geriatric horses, ensuring their welfare. These are stated aims of the review, not results of a study; the abstract reports no measured outcomes, sample or follow-up.
Supporting source [1]
How to interpret this
Abstract only; the full text was not reviewed. The abstract reports no study design, sample, follow-up or measured outcomes, and the proposed translational models and care implications are not validated results.
Based on the study abstract; the full paper, tables and supplementary data were not reviewed.
Source & supporting passages
Maria Puchalska, Olga Witkowska‐Piłaszewicz · doi.org · May 11, 2026