Jamie Justice: The New Metrics of Functional Aging

XPRIZE Healthspan Executive Director Jamie Justice joins Brianna Stubbs to discuss the $101 million race to restore 10 years of muscle, cognitive, and immune function within a single year. Moving past binary "alive or dead" metrics—famously called the "toes test" in animal research—the conversation focuses on reclaiming functional independence through clinical trial innovation. Together they explore the potential of accessible markers like RDW (Red Cell Distribution Width), the risks of overlapping treatments, and how unlocking "dark data" can help shift medicine from treating isolated diseases to scaling human healthspan globally. Jamie is the Executive Vice President of the Health Domain at XPRIZE Foundation, and Adjunct Professor in Internal Medicine Section on Gerontology and Geriatric Medicine, and Sticht Center on Healthy Aging and Alzheimer’s Prevention at Wake Forest University School of Medicine (WFUSM). She is dedicated to Geroscience research that advances the hypothesis that by targeting the basic biology of aging the incidence of multiple age-related diseases can be delayed or prevented.  Support the show (https://www.buckinstitute.org/donate/)