Possible osteosarcopenia linked to lower intrinsic capacity and early cognitive deficits in Singapore older adults
In a Singapore household survey of 2,291 older adults, possible osteosarcopenia was common and was associated with lower intrinsic capacity at baseline and poorer cognition at 6 months. [1]
Automatic summary · not editorially reviewed
The key findings
Possible osteosarcopenia, defined as concurrent possible osteoporosis and possible sarcopenia, was observed among 50.3% of the cohort. [1]
Possible osteosarcopenia was associated with lower intrinsic capacity at baseline, including cognition capacity. [1]
Baseline possible osteosarcopenia was associated with poor cognitive function at 6 months after baseline, particularly among those with loss in cognitive capacity at baseline. [1]
The source at a glance
- Study type / format
- Longitudinal observational study (abstract).
- Population / context
- 2,291 older adults recruited through a national household survey in Singapore.
- Summary based on
- Study abstract
- Original publication
- October 1, 2026
Singapore survey of 2,291 older adults
Participants were recruited through a national household survey of older adults in Singapore. Questionnaires and physical assessments at baseline collected socio-demographic, health and psychosocial variables. Possible osteosarcopenia was defined as the concurrent presence of possible osteoporosis and possible sarcopenia. The study reports that this possible osteosarcopenia was observed among 50.3% of the cohort.
Supporting source [1]
Lower intrinsic capacity at baseline, poorer cognition at 6 months
Using multilevel mixed-effects regression models, the authors examined associations of possible osteosarcopenia with intrinsic capacity at baseline and with cognitive function at 6 months after baseline. Possible osteosarcopenia was associated with lower intrinsic capacity at baseline, including cognition capacity. Baseline possible osteosarcopenia was also associated with poor cognitive function at 6 months, particularly among those with loss in cognitive capacity at baseline. This was driven by impaired delayed recall and poor orientation abilities.
Supporting source [1]
Education, social networks and resilience linked to better capacity
The authors also report that higher education, social networks, resilience and quality of life were associated with better intrinsic capacity at baseline and better cognition at baseline and at 6 months after baseline. These are associations, not evidence that any factor causes better capacity or cognition. The abstract does not report effect sizes, confidence intervals or adjustment details, and the full text was not reviewed.
Supporting source [1]
How to interpret this
Abstract only; the full text was not reviewed. The abstract reports associations, not causes, and gives no effect sizes, confidence intervals or adjustment details.
Based on the study abstract; the full paper, tables and supplementary data were not reviewed.
Source & supporting passages
Koh VJW, Khong TMT, Troeung L, Malhotra R, Jha D, Praveen AD, Liu YX, Helgason B, Singh NB, Chan AWM. · europepmc.org · October 1, 2026