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Video library· Modern HealthspanAudio: English

Should You Take a Multivitamin? A Harvard Researcher’s Verdict | Dr Howard Sesso & Dr Li Sidong

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Creator description · original textText language: English

Dr. Howard Sesso of Harvard explains the results of the COSMOS trial, identifying who actually benefits from a daily multivitamin and how it impacts biological aging. Some links are affiliate links so we will earn a commission when they are used to purchase products. If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan ~~~~~~~~~~~~~~ *Qualia* (15% off: MODERN) Creatine+ https://tinyurl.com/mr3z35jd Senolytic https://bit.ly/4jlaibe *Renue By Science* (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR *BiOptimizers* (15% off: MHBIO) https://bit.ly/47VAa8f - Magnesium Breakthrough, Gluten Guardian *Seeking Health* (10% off: Richard10) https://crrnt.app/SEEK/-dm0MyrQ, Histamine Nutrients https://crrnt.app/SEEK/EpM7paAO *Stemregen* (15% off: MODERN) *US only* https://tinyurl.com/45z968yr *MitoQ* https://tinyurl.com/5n93fm3f MitoQ Pure https://tinyurl.com/3hxy9s7x *Wellness Extract* (10% off: MODERNWE) http://wellnessextract.com/RICHARDWE Geranylgeraniol • Vit E *n1o1* (10% off: Modern) https://tidd.ly/3IczGRW - Nitric Oxide Lozenges *AX3 Life* (20% off: MODERN20) https://tinyurl.com/2t3w26nw - Astaxanthin *Qitone* (10% off: HEALTH10) https://tidd.ly/4jGklry Qitone Esters Powder *Oxford Healthspan* (15% off: MHS) https://tinyurl.com/hrxfnzpn - Spermidine *ProHealth* (15% off: MODERN) https://prohealth.pxf.io/aObQRR NMNH 500mg These are affiliate links - using them supports the channel at no extra cost to you. ~~~~~~~~~~~~~~ Is a daily multivitamin a life-extending "insurance policy" or just a waste of money? In this clip, Dr. Howard Sesso, Co-Principal Investigator of the landmark COSMOS trial, breaks down the clinical evidence from over 21,000 participants. We explore the "sweet spot" of nutritional insufficiency; where you aren't clinically deficient but lack the levels needed for optimal healthspan. Dr. Sesso and Dr. Sidong Li discuss how multivitamins specifically slowed the "epigenetic clock" in individuals with existing risk factors like hypertension and accelerated biological aging. We also cover the importance of "precision nutrition" and why the synergy of essential vitamins and minerals may be more effective than high-dose single supplements. If you’re looking for a common-sense, evidence-based approach to basic supplementation, this deep dive into the Harvard-led COSMOS data provides the answers you need. 📚 Chapters 0:00 The "Insurance Policy" Strategy for Supplements 0:55 Is a Multivitamin a Waste of Money? 1:57 Who Benefits Most? (Sub-Analysis Results) 4:04 The Impact of Hypertension & Health Risks 6:25 Nutritional Insufficiency vs. Overt Deficiency 8:36 Evidence: Do Biomarkers Actually Change? 🌐Links in this video COSMOS Trial home page https://cosmostrial.org/ Effects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial https://www.nature.com/articles/s41591-026-04239-3 #EpigeneticAging #Multivitamins #BiologicalAge

Modern Healthspan · 10 min · Source published: 2026-04-19

Added to Harbor: 10/23/2026

Original on YouTube ↗

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