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Video library· Jeff Heidelberger

NMN & NR: The NAD+ Precursors That Could Change Aging

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There are two supplements that billionaires take, researchers argue about, and the FDA treats completely differently. NMN and NR both boost NAD+ — the molecule David Sinclair calls "the fuel of longevity." In this video, we break down: • What NAD+ is and why it declines with age • How NMN and NR work (and the difference between them) • The animal science — healthspan vs lifespan • What human trials actually show • The NMN vs NR debate (Sinclair vs Brenner) • Dosing, safety, and the regulatory reality Timestamps: 0:00 — Hook 0:35 — What Is NAD+? 1:25 — NMN vs NR 2:15 — The Animal Science 3:15 — What Human Trials Show 4:20 — The NMN vs NR Debate 5:20 — Dosing and Safety 6:10 — Bottom Line Subscribe for more evidence-based longevity content: https://www.youtube.com/@jeffheidelberger #longevity #NMN #NR #NAD #antiaging #supplements #science Tags: NMN, NR, NAD+, longevity, anti-aging, David Sinclair, nicotinamide riboside, nicotinamide mononucleotide, supplements, biohacking, longevity science, healthspan

Jeff Heidelberger · 8 min · Source published: 2026-05-07

Added to Harbor: 10/22/2026

Original on YouTube ↗

Automatically categorized source. Creator statements are not an independent evidence review or personal medical guidance.

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